let’s play gene mutations chromosomal mutations

75

Upload: hubert-brooks

Post on 18-Dec-2015

225 views

Category:

Documents


3 download

TRANSCRIPT

Page 1: Let’s Play Gene Mutations Chromosomal Mutations
Page 2: Let’s Play Gene Mutations Chromosomal Mutations

Let’s Play

Page 3: Let’s Play Gene Mutations Chromosomal Mutations

Gene Gene MutationsMutations

Page 4: Let’s Play Gene Mutations Chromosomal Mutations

ChromosoChromosomal mal

MutationsMutations

Page 5: Let’s Play Gene Mutations Chromosomal Mutations

Gene Gene Expression Expression

Part 1Part 1

Page 6: Let’s Play Gene Mutations Chromosomal Mutations

Gene Gene Expression Expression

Part 2Part 2

Page 7: Let’s Play Gene Mutations Chromosomal Mutations

DNADNA

Page 8: Let’s Play Gene Mutations Chromosomal Mutations

RNARNA

Page 9: Let’s Play Gene Mutations Chromosomal Mutations

200

300

400

500

Gene Mutation

Chromosomal

Mutation

Gene Expression

1

Gene Expression

2DNA RNA

100

200

300

400

500

100

200

300

400

500

100

200

300

400

500

100

200

300

400

500

100

200

300

400

500

100

Page 10: Let’s Play Gene Mutations Chromosomal Mutations

The type of gene mutation that only

affects a single amino acid.

Page 11: Let’s Play Gene Mutations Chromosomal Mutations

What is a substitution mutation?

Page 12: Let’s Play Gene Mutations Chromosomal Mutations

The type of gene mutation that causes

all of the following nucleotides to move to the left one space.

Page 13: Let’s Play Gene Mutations Chromosomal Mutations

What is a deletion mutation?

Page 14: Let’s Play Gene Mutations Chromosomal Mutations

DailyDouble!

Page 15: Let’s Play Gene Mutations Chromosomal Mutations

Where is at the third base

(nucleotide) in the codon?

Page 16: Let’s Play Gene Mutations Chromosomal Mutations

Gene mutation that causes all the

nucleotides that follow to move to the right one

space.

Page 17: Let’s Play Gene Mutations Chromosomal Mutations

What is an insertion

mutation?

Page 18: Let’s Play Gene Mutations Chromosomal Mutations

The term for the two types of mutations that affect all the remaining amino

acids in the polypeptide.

Page 19: Let’s Play Gene Mutations Chromosomal Mutations

What is a Frameshift mutation?

Page 20: Let’s Play Gene Mutations Chromosomal Mutations

When a chromosome has a portion of genetic information repeated, this type of mutation

has occurred.

Page 21: Let’s Play Gene Mutations Chromosomal Mutations

What is a duplication mutation?

Page 22: Let’s Play Gene Mutations Chromosomal Mutations

The type of mutation that involves the

removal of a part of the chromosome.

Page 23: Let’s Play Gene Mutations Chromosomal Mutations

What is a deletion mutation?

Page 24: Let’s Play Gene Mutations Chromosomal Mutations

This series of images illustrates this type of

chromosomal mutation.> >

Page 25: Let’s Play Gene Mutations Chromosomal Mutations

What is DNA helicase?

What is an inversion mutation?

Page 26: Let’s Play Gene Mutations Chromosomal Mutations

This is image is displaying this type

of mutation.

Page 27: Let’s Play Gene Mutations Chromosomal Mutations

What is an inversion mutation?

What is a translocation

mutation?

Page 28: Let’s Play Gene Mutations Chromosomal Mutations

DailyDouble!

There have been cases of Males with

chromosome XX. This is possible because of the

translocation of this region.

Page 29: Let’s Play Gene Mutations Chromosomal Mutations

What is the SRY gene?

Page 30: Let’s Play Gene Mutations Chromosomal Mutations

The complementary base pair for Adenine

in RNA.

Page 31: Let’s Play Gene Mutations Chromosomal Mutations

What is Uracil?

Page 32: Let’s Play Gene Mutations Chromosomal Mutations

The process of copying DNA onto

mRNA.

Page 33: Let’s Play Gene Mutations Chromosomal Mutations

What is transcription?

Page 34: Let’s Play Gene Mutations Chromosomal Mutations

The first step of gene expression

occurs here.

Page 35: Let’s Play Gene Mutations Chromosomal Mutations

Where is the nucleus?

Page 36: Let’s Play Gene Mutations Chromosomal Mutations

This enzyme creates mRNA by assembling free ribonucleotides

complementary to the DNA.

Page 37: Let’s Play Gene Mutations Chromosomal Mutations

What is RNA Polymerase?

Page 38: Let’s Play Gene Mutations Chromosomal Mutations

These noncoding regions must be

removed from the mRNA before it

leaves the nucleus.

Page 39: Let’s Play Gene Mutations Chromosomal Mutations

What are introns?

Page 40: Let’s Play Gene Mutations Chromosomal Mutations

This step of gene expression when the polypeptide is

assembled.

Page 41: Let’s Play Gene Mutations Chromosomal Mutations

What is translation?

Page 42: Let’s Play Gene Mutations Chromosomal Mutations

Locations in cytoplasm where translation takes

place.~two answers~

DailyDouble!

Page 43: Let’s Play Gene Mutations Chromosomal Mutations

What are the free floating

ribosomes and Rough ER?

Page 44: Let’s Play Gene Mutations Chromosomal Mutations

This RNA brings the monomers of

proteins to the site of protein

synthesis.

Page 45: Let’s Play Gene Mutations Chromosomal Mutations

What is the tRNA?

Page 46: Let’s Play Gene Mutations Chromosomal Mutations

The organelle where translation

occurs.

Page 47: Let’s Play Gene Mutations Chromosomal Mutations

What is the ribosome?

Page 48: Let’s Play Gene Mutations Chromosomal Mutations

These codons signal to the

ribosome that the polypeptide has been finished.

Page 49: Let’s Play Gene Mutations Chromosomal Mutations

What are UGA, UAA, and UAG?

Page 50: Let’s Play Gene Mutations Chromosomal Mutations

The term we use to refer to the

structure of DNA.

Page 51: Let’s Play Gene Mutations Chromosomal Mutations

What is a double helix or twisted

ladder?

Page 52: Let’s Play Gene Mutations Chromosomal Mutations

This sugar, found in DNA, lacks an

oxygen when compared to the

sugar of RNA.

Page 53: Let’s Play Gene Mutations Chromosomal Mutations

What is deoxyribose

sugar?

Page 54: Let’s Play Gene Mutations Chromosomal Mutations

These are the four possible bases on

DNA.

Page 55: Let’s Play Gene Mutations Chromosomal Mutations

What are adenine, thymine, cytosine,

and guanine?

Page 56: Let’s Play Gene Mutations Chromosomal Mutations

Organelle that stores and

protects DNA.

Page 57: Let’s Play Gene Mutations Chromosomal Mutations

What is the nucleus?

Page 58: Let’s Play Gene Mutations Chromosomal Mutations

These are the building blocks of

nucleic acids.

Page 59: Let’s Play Gene Mutations Chromosomal Mutations

What are nucleotides?

Page 60: Let’s Play Gene Mutations Chromosomal Mutations

When compared to DNA the

structure of the RNA molecule is referred to as…

Page 61: Let’s Play Gene Mutations Chromosomal Mutations

What is single stranded?

Page 62: Let’s Play Gene Mutations Chromosomal Mutations

The sugar of ribonucleic acid.

Page 63: Let’s Play Gene Mutations Chromosomal Mutations

What is ribose?

Page 64: Let’s Play Gene Mutations Chromosomal Mutations

These four nitrogen bases

are found in ribonucleic acids.

Page 65: Let’s Play Gene Mutations Chromosomal Mutations

What are adenine, uracil, cytosine, and guanine?

Page 66: Let’s Play Gene Mutations Chromosomal Mutations

This is the role of-mRNA-rRNA-tRNA

DailyDouble!

Page 67: Let’s Play Gene Mutations Chromosomal Mutations

What are to copy the info from DNA, a component of the

ribosome, and brings the amino acid to the

ribosome?

Page 68: Let’s Play Gene Mutations Chromosomal Mutations

These are the three types of

RNA.~Full word, not just letter abbreviation~

Page 69: Let’s Play Gene Mutations Chromosomal Mutations

What are messenger RNA, ribosomal RNA,

and transfer RNA?

Page 70: Let’s Play Gene Mutations Chromosomal Mutations
Page 71: Let’s Play Gene Mutations Chromosomal Mutations

Topic:

Mutations

Page 72: Let’s Play Gene Mutations Chromosomal Mutations

The mutation The mutation between these two between these two DNADNA standsstands will will

have this result on have this result on the final polypeptide.the final polypeptide.Original: TAC-CAT-GTC-Original: TAC-CAT-GTC-

AGC-ATTAGC-ATTMutated: TAC-GAT-GTC-Mutated: TAC-GAT-GTC-

AGC-ATTAGC-ATT

Page 73: Let’s Play Gene Mutations Chromosomal Mutations

Original DNA: TAC-CAT-GTC-Original DNA: TAC-CAT-GTC-AGC-ATTAGC-ATT

Mutated DNA: TAC-GAT-GTC-Mutated DNA: TAC-GAT-GTC-AGC-ATTAGC-ATT

Page 74: Let’s Play Gene Mutations Chromosomal Mutations

Original: TAC-CAT-GTC-Original: TAC-CAT-GTC-AGC-ATTAGC-ATT

mRNA: AUG-GUA-CAG-mRNA: AUG-GUA-CAG-UCG-UAAUCG-UAA

AAs: Met-Val-Glu-Ser AAs: Met-Val-Glu-Ser

Mutated: TAC-GAT-GTC-Mutated: TAC-GAT-GTC-AGC-ATTAGC-ATT

mRNA: AUG-CUA-CAG-mRNA: AUG-CUA-CAG-UCG-UAAUCG-UAA

AAs: Met-Leu-Glu-SerAAs: Met-Leu-Glu-Ser

Page 75: Let’s Play Gene Mutations Chromosomal Mutations

DailyDouble!