THE GLYTOL TRAIT IN COTTON

As the first season-long glyphosate-tolerant alternative to Roundup Ready Flex®, GlyTol provides cotton farmers the option to choose any brand of glyphosate labeled for use on cotton, allowing them greater flexibility in their weed management decisions. GlyTol glyphosate-tolerant technology gives growers a competitive edge with a wide window of application and additional trait combinations.

Extensive laboratory, greenhouse and field trials across the Cotton Belt have been conducted to evaluate crop tolerance and agronomic characteristics of cotton containing GlyTol technology including germination, emergence, plant growth, vigor, yield, harvestability and fiber quality.

Research and development activities have shown that GlyTol technology offers:

• Proven crop safety to various glyphosate formulations with no impact on yield, quality or plant height.

• A wide application window for over-the-top applications of glyphosate.

• Production efficiency and flexibility to allow growers to make the right decisions for their farm.

THE LIBERTYLINK TRAIT IN COTTON

• Using Liberty herbicide on cotton varieties with the LibertyLink trait provides effective weed management and enables nonselective herbicide rotation.

• Liberty is a nonselective contact herbicide that provides postemergence control of broadleaf and grass weeds in LibertyLink cotton, including weeds resistant to glyphosate and other herbicide classes.

• As part of a LibertyLink cotton system, Liberty provides fast control of weeds within days vs. weeks, minimizing competition with early season weeds and maximizing potential for high yield and quality.

• Liberty has a unique mode of action (Group 10) that offers a nonselective alternative for Integrated Weed Management plans.

THE GLYTOL LIBERTYLINK TRAIT STACK IN COTTON

GlyTol LibertyLink (GL) technology in cotton brings an industry first—the ability for growers to make over-the-top applications of either glyphosate or Liberty herbicide with full commercial tolerance to both herbicides. This innovation provides even greater flexibility in weed management and management of glyphosate-resistant weeds. GL-traited cotton also protects against the potential for damage due to off-target movement of glyphosate or Liberty from nearby fields.

TWINLINK* TRAIT STACK IN COTTON

TwinLink technology offers two-gene Bt (Bacillus thuringiensis) protection against worm pests plus LibertyLink technology that gives full tolerance to Liberty herbicide. TwinLink is stacked with GlyTol to provide double-herbicide tolerance to Liberty and glyphosate for effective crop and insect resistance management. TwinLink cotton contains two Bayer CropScience proprietary Bt genes that encode production of insecticidal proteins, Cry1Ab and Cry2Ae. This two-gene insect protection system provides season-long protection from important leaf- and fruit-feeding Lepidopteran pests. TwinLink facilitates better insect management in your cotton crop by controlling key pests, including tobacco budworm, pink bollworm and bollworm. TwinLink also controls beet armyworm, fall armyworm, cabbage looper, soybean looper and other occasional and secondary leaf- or fruit-feeding caterpillar pests of cotton. Insecticide applications to manage caterpillar pests are significantly reduced with TwinLink. Cotton stacked with GlyTol, LibertyLink and TwinLink will be a powerful weed and insect management tool for growers.

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INSEED™ TRAIT IDENTIFICATION SYSTEM

The InSeed™ trait identification system consists of the following traits, easily identified on bags appropriate for each unique need.

HERBICIDE TOLERANCE

This icon illustrates herbicide tolerance and indicates which herbicides can be used. LibertyLink indicates that the herbicide Liberty can be applied to cotton. GlyTol indicates that glyphosate herbicides can be sprayed. When LibertyLink and GlyTol are indicated, it means that both Liberty and glyphosate herbicides can be used in a program, conferring a double herbicide-tolerant property to cotton.

INSECT RESISTANCE

This icon illustrates insect resistance. TwinLink is a new Bayer CropScience insect resistance product providing two-gene insect-resistant protection against Lepidopteran pests (budworm/bollworm complex). In the future, other pests (aphids, Lygus, etc.) will be controlled by new traits.

HERBICIDE TOLERANCE/INSECT RESISTANCE

The insect resistance icon paired with the herbicide tolerance icon indicates that this cottonseed has both properties. GlyTol and LibertyLink stacked with TwinLink provides two-gene insect-resistant protection and double herbicide tolerance.

* It is anticipated that the first varieties with TwinLink will be available in both FiberMax and Stoneville brands in the United States beginning in 2014, pending international import approvals. 28

THE FUTURE IS FILLING UP

Keep an eye on our pipeline—this is only the beginning. The InSeed trait identification system will continue to grow, because Bayer CropScience is committed to bringing the latest innovations in cotton to growers each and every day. InSeed is just the latest step in a process that starts in our pipeline and ends with quality products.

WHERE TO FIND COTTON VARIETIES WITH GLYTOL, LIBERTYLINK AND TWINLINK TRAITS

• The LibertyLink trait technology is currently available in high-yielding, high-quality FiberMax and Stoneville cotton seed varieties.

• GlyTol trait technology is currently available in high-yielding, high-quality FiberMax varieties.

• GlyTol LibertyLink stacked technology is available in elite, high-performing FiberMax cotton varieties and will soon be available in Stoneville varieties.

• GlyTol LibertyLink Bollgard II® is available in high-yielding FiberMax and Stoneville varieties.

• For more information about FiberMax and Stoneville cotton seed varieties, go to www.FiberMax.com or www.Stoneville.com

Download the Variety Selector Tool™ from there or get it as an app on your smart phone.

• Contact your local seed dealer/distributor or Bayer CropScience representative about where to find the latest varieties available.

COMPLIANCE MONITORING PROGRAM

The U.S. EPA requires Bayer CropScience to take corrective action in response to a finding of noncompliance by growers to the refuge requirements of GlyTol LibertyLink TwinLink cotton. Bayer CropScience or an approved agent of Bayer CropScience is required to monitor compliance with refuge requirements. The Bayer Grower Technology Agreement stipulates that, upon request by Bayer CropScience or an approved agent, a grower must provide the location of all fields planted with Bayer CropScience biotechnologies and the locations of all associated required refuge areas so that they may be verified to be in compliance with GlyTol LibertyLink TwinLink registration requirements. Bayer CropScience will provide the grower advance notice of any inspec-tions, and such inspections will be performed dur-ing regular working hours to accommodate the grower’s schedule so the grower may be present if desired.

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1. Start Clean. Start with a clean, weed-free field by using an effective burndown application or conventional tillage.

2. Stay Clean. Use an Overlapping Residual Weed Control Program. Be aggressive with early season weed management to avoid yield loss and weed escapes. Residual herbicides applied at burndown, pre-emergence and/or tankmixed in the first post application help ensure optimal weed management, particularly if environmental conditions delay timely post applications. Consider expected weed species and populations as well as environmental variables in the area when selecting a residual herbicide.

3. Scenario One—Residual Used Pre-emergence, PPI or At Planting:

a. Apply Liberty at 29 fl oz/A over the top of LibertyLink cotton from crop emergence to 14 days after crop emergence or when weeds are no more than 3 inches to 4 inches tall.

b. Apply Liberty at 29 fl oz/A on as-needed basis following the first application at 29 fl oz/A.

4. Scenario Two—Environmental Conditions Prevent Timely Application:

a. If environmental conditions prevent timely Liberty application, a single application of up to 43 fl oz/A may be made in the first application.

b. If 43 fl oz/A is used for the first application, a second application of 29 fl oz/A should be made 10 days after the first application. Increase water and shorten interval between post applications if canopy is heavy.

c. A third application of 29 fl oz/A can also be made in cotton on an as-needed basis, only if the previous two applications did not exceed 29 fl oz/A in either application.

5. Maximum Seasonal Use: Up to 72 fl oz/A or 87 fl oz/A of Liberty can be applied on cotton per growing season. See Liberty label for guidelines on maximum seasonal use rates.

6. Additional Use Directions: a. Liberty and glyphosate tankmixes are

antagonistic and may reduce overall weed control. Therefore, tankmixes of these two products are NOT recommended.

b. Do NOT apply glyphosate within seven days following a Liberty application or reduced herbicide efficacy may occur.

c. Full rates of Liberty are recommended regardless of tankmix herbicide.

d. Make all applications when wind speeds are less than 10 mph, and not during periods of temperature inversions.

e. Do not exceed 87 fl oz/A of Liberty per season.

f. Do not apply within 70 days of harvest.

g. Consult product label for full use directions and restrictions.

RECOMMENDATIONS FOR WEED MANAGEMENT IN FIBERMAX AND STONEVILLE COTTON WITH LIBERTYLINK TECHNOLOGY

Weed Control Program 1st Post Application (Emergence to 14 days)

2nd Post Application

Scenario OneResidual pre-emergence, PPI or at planting

Liberty at 29 fl oz/A plus residual herbicide

If needed, Liberty at 29 fl oz/A

Scenario TwoEnvironmental conditions prevent timely application

Liberty at 43 fl oz/A plus residual herbicide

Liberty at 29 fl oz/A applied 10 days after the first application

APPLICATION INFORMATION AND BEST WEED MANAGEMENT PRACTICES

POSTEMERGENCE OVER-THE-TOP TANKMIX PARTNERS FOR LIBERTY ON LIBERTYLINK COTTON

Assure II (1*) clethodim (1) Fusilade DX (1) Fusion (1)

metolachlor (15) Poast Plus (1) Select Max (1) Staple (2)

* Numbers in parentheses denote herbicide MOA as designated by the Weed Science Society of America.

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KEY APPLICATION POINTS TO REMEMBER

• Uniform, thorough spray coverage is essential to achieve consistent performance.

• Use nozzles and pressure that generate a medium-size spray droplet.

• Use 15 GPA (in dense canopies, increase water volume).

• Maximum performance is achieved when applications are made to actively growing weeds.

• Apply from emergence to early bloom growth stage.

• Sequential applications should be applied at 10 days after the first application.

• Liberty is rainfast in four hours.

TOP 10 MOST FREqUENTLY SPRAYED WEEDS IN COTTON

YIELD LOSS DUE TO COMPETITION

Weeds that emerge with the crop, or shortly thereafter, have the greatest potential to adversely impact yields. The yield loss associated with this flush of weeds is strongly influenced by how long weeds are allowed to remain in the field and compete with crops for light, water and nutrients. Weed scientists state that effective weed control during the first nine weeks after emergence is critical to produce optimum cotton yields.

Residual herbicides improve weed control, reduce problematic weeds and extend the time period between planting and the first postemergence treatment of Liberty herbicide. Furthermore, the use of residual herbicides increases application flexibility in case of unfavorable weather conditions. Use a residual herbicide in your weed control program to introduce another herbicide mode of action in the field and enhance your resistance management program.

According to a 2010 University of Tennessee study4, cotton and soybean growers lost nearly $138 million due to glyphosate-resistant Palmer amaranth. Their weed control costs also increased as follows:

• $78.5 million in increased herbicide costs $35 per acre on 1.6 million soybean acres $55 per acre on 0.4 million cotton acres

• $10 million in increased application costs $5 per acre on 2 million acres

• $49.35 million due to glyphosate-resistant weed competition 30 percent of soybean acres at 17 percent loss 15 percent of cotton acres at 25 percent loss

YIELD LOSS EXAMPLES

Research in Georgia8 in 2006 and 2007 noted that two glyphosate-resistant Palmer amaranth spaced every 7 meters of row (91-cm row spacing) reduced cotton yield by 23 percent.

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1If more than 29 fl oz/A is used in any single application, the season total may not exceed 72 fl oz/A, including all application timings. 2For best control, do not apply before weeds reach 6 inches tall. 3Sequential applications may be needed for populations of weeds with mixed heights. 4Treat prior to tiller.

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Max. Weed Height with Liberty at 29 fl oz/A1

Confirmed Glyphosate-Resistant Weeds

Amaranth (Palmer, redroot and tumbleweed)

4” ✔

Morningglory 8”

Johnsongrass4 5” ✔

Cocklebur 14”

Crabgrass4 5”

Marestail2,3 6”-12” ✔

Russian thistle2,3 6”-12”

Sicklepod 6”

Texas panicum 6”

Barnyardgrass 5” ✔

*Start yield at 1,000 lb/A. **Represents CCC Loan Rate.

$/Pound

$0.52** $0.60 $0.65

Lost $/A from Palmer amaranth*

$119.60 $138 $149.50

Lost $/1000 A* $119,600 $138,000 $149,500

4,8 See page 36 for source information.

“Resistance is a real concern. It’s a problem. It’s not going to go away. It’s something we’re going to have to learn to

live with and manage.” – Dr. Alan York, North Carolina State University