linking assertions to evidence with the micropublications ontology wg evidence 2014-03-26
DESCRIPTION
How can we link assertions to evidence in the scientific literature? Discussion about the MicroPublications ontology (http://purl.org/mp/ & see http://arxiv.org/abs/1305.3506 ) Presented to the WG Evidence Panel of the Addressing PDDI Evidence Gaps project https://sites.google.com/site/ddikrandir/home/wg-evidence-panelTRANSCRIPT
Linking assertions to evidence with the MicroPublications ontology
Jodi Schneiderhttp://jodischneider.com/jodi.html
WG Evidence - Addressing PDDI Evidence GapsMarch 26, 2014
goalRecord relationships between assertions and evidence
Assertions: “there (is/is not) an interaction between A & B”“Enzyme E reduces clearance of drug D by 25%”
Evidence: Scientific literature, drug product labeling, FDA guidance documents
Boyce’s DIKB
DIKB Assertions (siocns:content) “The aim of this study was to compare the pharmacokinetics of diltiazem its major metabolites in healthy human volunteers representing different CYP2D6 genotypes.”
Evidence type (dikbEvidence:Evidence_type)
dikbEvidence:EV_CT_PK_Genotypesupports (is swanco:citesAsSupportingEvidence of)<http://dbmi-icode-01.dbmi.pitt.edu/dikb/resource/Assertions/9>
desacetyldiltiazem_substrate_of_cyp2d6
• Evidence
MicropublicationsModel the relationship between assertions and evidence
Features:Designed for bioinformaticsImproves on previous modelsIntegrates annotation (Domeo)Enhanced argumentative reasoning
Micropublications
Micropublications
Micropublications: a Semantic Model for Claims, Evidence, Arguments and Annotations in Biomedical CommunicationsTim Clark, Paolo N. Ciccarese, Carole A. Goblehttp://arxiv.org/abs/1305.3506
Micropublications: a Semantic Model for Claims, Evidence, Arguments and Annotations in Biomedical CommunicationsTim Clark, Paolo N. Ciccarese, Carole A. Goblehttp://arxiv.org/abs/1305.3506
Micropublications
Micropublications: a Semantic Model for Claims, Evidence, Arguments and Annotations in Biomedical CommunicationsTim Clark, Paolo N. Ciccarese, Carole A. Goblehttp://arxiv.org/abs/1305.3506
Micropublications as a new evidence model
Can micropublications be used in the next version of the DIKB?
Micropublications: a Semantic Model for Claims, Evidence, Arguments and Annotations in Biomedical CommunicationsTim Clark, Paolo N. Ciccarese, Carole A. Goblehttp://arxiv.org/abs/1305.3506
