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    Anatomy of

    Liver, Biliary system

    &Portal vein

    Dr Mohamad Aris Mohd Moklas (PhD)Department of Human AnatomyFPSK [email protected] 8947 2330/2331/2783

    mailto:[email protected]:[email protected]:[email protected]:[email protected]:[email protected]:[email protected]:[email protected]:[email protected]
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    LIVER

    It is the largest gland in

    the body. Liver is a soft, dark

    brown highly vascularorgan. It is readily torn inabdominal injur ies

    causing severe intra-abdominal bleeding.

    In adult it is

    approximately 2% of the

    body weight.

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    LIVER

    LocationMainly

    present in right

    hypochondriac region . It

    also extends to epigastricregion.

    Weight-

    1400

    1800 gms in males.12001400 gms in females.

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    Lobes of liver Liver is divided into a large right lobe and a

    small left lobe by the attachment of falciformligament , which extends from liver to theanterior abdominal wall.

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    Lobes of liver

    Right lobe is further divided into quadratelobe and caudate lobe.

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    Surfaces of l iver

    Five surfaces,anterior, posterior,superior, inferior and

    right surfaces.

    A sharp inferior

    border separates theanterior from the

    inferior surface.

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    Relations of l iver:

    Per itoneal relations

    &

    Visceral relations

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    Relations of l iver :

    Peritoneal relations

    Liver is covered by the visceral layer of peritoneumexcept the bare area of liver.

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    Relations of liver:

    Visceral relations

    Superiorly the liver is related to the diaphragm.

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    Relations of liver:

    Visceral relations

    Posteroinferiorsurface: (Posteriorand inferior)

    It is related toabdominal part ofoesophagus, the

    stomach, the

    duodenum, theright colic flexure,the right kidney,right suprarenaland the gallbladder.

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    Relations of liver:

    Visceral relations

    Posteroinferiorsurface: (Posteriorand inferior)

    Groove for Inferiorvena cava lodgesthe upper part of

    I.V.C.

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    Abdominal part of oesophagus is related to theposterior surface of the left lobe.

    Bare area is related to the posterior surface of rightlobe .

    Stomach is related to the inferior surface of the left

    lobe.

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    Right kidney and right colic flexure are related to theinferior surface of the right lobe .

    Gall bladder fossa lodges the gall bladder on theinferior surface .

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    Gastric

    Colic

    Renal

    Left triangular ligament

    Ligamentum teres

    Bare area

    Coronary ligamentsHepatic vein

    Quadratelobe

    Porta hepatis

    Fissure for

    ligamentum

    venosum

    Fissure for

    ligamentumteres hepatis

    Falciform ligament

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    Porta hepatis of l iver (H ilum)

    It is present on theposteroinferior surface andlies inbetween caudate and quadrate lobes.

    Free edge of the lesser omentum is attached to its

    margins.

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    Porta hepatis of

    liver (H ilum)

    Right and lefthepatic ducts, right

    and left branches ofhepatic artery andportal vein are passing

    throughthe porta

    hepatis.

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    Vascular segments of Liver

    On the basis of blood supply and biliary drainagethere are four main hepatic segments.

    Left lateral (left lobe) Left medial (Left lobe) Right anterior (right lobe) Right posterior (right lobe)

    Each of these main segments are furthersubdivided into upper and lower parts.

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    Peritoneal l igaments of l iver

    1. Falciform ligamentIt is a two- layered fold ofperitoneum.

    It extends from the anterior abdominal wall to theanterior surface of liver.

    I t contains the l igamentum teres, which is theremains of the umbilical vein.

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    The right layer of falciform ligament forms theupper layer of the coronary ligament and its left layer

    forms the upper layer of the left triangular ligament.

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    Peritoneal ligaments of

    liver

    2. The lesser omentum -

    It extends from theedges of theportahepatis and passes to

    the lessercurvature ofstomach.

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    Lesser omentum

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    Bare areaof liver

    This is the area of l iver which is devoid ofperitoneum.

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    Bare areaof liver

    To the right of the I.V.C the posterior part of thediaphragmatic surface is broad and a large part of itbetween the superior and inferior layers of the coronary

    ligament is not covered by peritoneum

    This is the bare area. Groove for I.V.C and the fossa for gall bladder are

    also devoid of peritoneum.

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    Blood supply

    Hepatic artery, abranch of celiacartery. It divides intoright and left

    terminal branchesthat enter the portahepatis.

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    VeinsPortal vein divides into right and left

    branches that enter the porta hepatis.

    The hepatic veins emerge from the posteriorsurface of liver and drain into the I.V.C.

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    Blood vessels of liver

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    Nerve supplySympathetic and

    parasympatheticfrom the celiac plexus.

    Lymphatic drainageThe efferent vessels pass

    to the celiac nodes.

    A few vessels from the bare area pass to the

    posterior mediastinal nodes.

    Bil i t

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    Bil iary system

    It consists of thefollowing structures.

    Right and left hepaticducts.

    Common hepatic duct.

    Gall bladder.

    Cystic duct.

    Common bile duct (bileduct).

    Bil i t

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    Bil iary system

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    Right and left hepatic ducts

    Emerge from the right and left lobes of the liver inthe porta hepatis.

    The hepatic ducts unite to form the common hepatic

    duct.

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    Common hepatic duct

    It is about 4 cm long. It descends within the freemargin of the lesser omentum. It is joined on the rightside by the cystic duct from the gall bladderto form

    the bile duct.

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    Gall bladder

    It is a pear-shaped sac.

    Lies on the undersurface of liver.

    Capacity 3050 ml.

    It has three partsFundus, bodyand neck. .

    Fundus usually projects below the

    inferior margin of liver and comesin contact with the anteriorabdominal wall .

    E t h ti t f th bil i t

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    Extr ahepatic parts of the bil iary system

    The bile ducts and the Gall bladder

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    Sur face marking of fundus of gal l bladder:

    Fundus can be surface marked on the anteriorabdominal wall at the level of the tip of the r ight 9th

    costal carti lage.

    The body of gall bladder lies in contact with the

    visceral surface of liver.

    The neck is continuous with the cystic duct.

    Theperitoneum completely surrounds the fundus ofgall bladder.

    Blood supply Cystic artery a branch of right hepatic artery

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    Blood supplyCystic artery a branch of right hepaticartery.

    VeinsCystic vein which drains into portal vein.

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    Lymphatic drainageDrains into cystic lymph node. From

    here the lymph vessels pass to hepatic nodes and then tocel iac nodes.

    Nerve supplySympathetic and parasympathetic.

    Parasympathetic is the vagus nerve. Sympathetic and parasympathetic form the celiac plexus.

    Thepain fibres from the gall bladder and bile ducts ascendthrough the celiac plexus

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    Cystic duct

    It is about 4 cm long.

    It connects the neck ofgall bladder to commonhepatic duct to form the bileduct.

    It descends in the freemargin of lesser omentum.

    Extrahepatic biliary apparatus

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    Bile duct (Common bile

    duct)

    It is about 8 cm long.

    It lies in the right free

    margin of lesser omentum.

    Here it lies in front of the

    portal vein and on the right of

    hepatic artery.

    Bile duct (Common bile

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    Bile duct (Common bile

    duct)

    Itpasses behind the firstpart of the duodenum .

    In the lower part of itscourse i t is poster ior tohead of pancreas.

    The bile duct is joined by the main pancreatic duct

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    The bile duct is joined by the main pancreatic ductto form hepatopancreatic ampul la(ampulla ofVater).

    The ampulla opens in the second part of the

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    The ampulla opens in the second part of theduodenum halfway down its length by means of asmall papilla major duodenal papilla.

    The terminal parts of both ducts and ampulla aresurrounded by asphincter of Oddi.

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    CLINICAL FEATURES

    1.Errors in gall bladder surgery is due to the failure to

    appreciate the variations in the anatomy of biliarysystem.

    It is therefore important to identify all the threebiliary ducts together with the cystic and hepaticarteries before dividing any structures and removing

    the gall bladder.

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    2.Haemorrhage during cholecystectomy can

    be controlled by compressing the hepaticartery between the finger and thumb when itlies in the anterior wall of the foramen of

    Winslow (epiploic foramen).

    3 St i th bil d t can s all be

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    3.Stones in the common bile ductcan usually beremoved through an incision in the supraduodenal

    part of the common bile duct.

    4. Bi liary colicSpasmodic pain in abdomen

    relating to bile passage. Biliary colic is mostintense when the calculus (stone) is impactedeither at the cystic duct or at the lower end of thebile duct.

    Biliary colic referred pain is felt in the right

    upper quadrant or the epigastrium.

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    5.Liver biopsyHepatic tissue may be

    obtained for diagnostic purposes by liverbiopsy.

    6.Rupture of liverLiver may be torn by afractured rib.

    7.HepatomegalyMany diseases cause liverenlargement, orhepatomegaly.

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    8.Cirrhosis of liverDestruction of hepatocytes and

    replacement of them by fibrous tissue.

    9.Liver transplantationA person with end stage

    liver disease may opt to have his liver removed to be

    replaced with a normal liver.

    10. Imaging of the biliary tractGall bladder and

    biliary tract can be demonstrated by ultrasound.

    --------------------------

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    Portal vein

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    Portal vein

    Portal vein drains blood from abdominal part ofthe gastrointestinal tract, from the lower third of

    oesophagus to half way down the anal canal.

    It also drains blood from thespleen, pancreas and

    gall bladder.

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    The portal circulationbegins as capillary plexusand ends by emptying blood into the sinusoids ofliver.

    Theportal vein enters the liver through the portahepatis.

    Bloodfrom liver is collected by hepatic veins. Hepatic veins join the I.V.C.

    Fig 20 The composition of the Portal system

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    Fig.20 The composition of the Portal system

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    Formation

    By the joining ofsuperiormesenter ic and splenicveins.

    Site of formationPosterior to neck ofpancreas.

    Length - 6 to 8 cm.

    Formation of portal Vein

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    Formation of portal Vein

    Relation of portal vein at its formation

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    Relations

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    At its formation, portal vein isposterior to neck ofpancreas.

    It passes upwards poster ior to first part of duodenum

    and enters the lesser omentum.

    In lesser omentum it is related anter ior ly to bi le

    duct (r ight), and hepatic artery (left). At the porta hepatis it divides into right and left

    branches.

    Relations of portal Vein

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    Portal Vein relations (In lesser omentum)

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    Portal Vein Tr ibutaries:

    i.Splenic vein It receives the inferiormesenteric vein.

    ii. Superior mesenteric vein

    iii. Left gastric veiniv. Right gastric vein

    v. Cystic vein.

    Tributaries of portal vein.

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    Portal - systemic anastomosis

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    Portal systemic anastomosis

    Smaller communications exist between the portal

    and systemic veins and they become importantwhen the direct route becomes blocked.

    These sites are,

    1. At the lower end of oesophagusThe

    oesophageal tributaries of the left gastric vein

    (Portal tributary) anastomose with oesophagealveins (systemic tributary).

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    2. Super ior rectal veinsdraining the upper part

    of the anal canal (Portal tributary)anastomose with middle and inferior rectalveins (systemic tributaries).

    3. Paraumbil ical veinsconnect the left branch

    of portal vein with superficial veins of

    anterior abdominal wall (systemictributaries).

    Portal-systemic anastomosis

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    CLINICAL FEATURES

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    CLINICAL FEATURES

    1. Portal hypertension

    Liver cirrhosis obstruct the portal vein resulting in

    increased pressure in portal vein causing portalhypertension.

    At the sites of portal caval anastomosis portal

    hypertension produces varicose veins. The veinsmay become so dilated that their walls ruptureresul ting in haemorrhage.

    Bleeding from oesophageal varices, extremelydilated submucosal veins in oesophagus (at

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    d ated sub ucosa ve s oesop agus (atthe distal end of the oesophagus) is often

    severe and may be fatal .Oesophageal varices

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    3. Paraumbil ical veinsmay become varicose

    and look like small snakes radiating underthe skin around the umbilicus.

    This condition is referred to as Caput

    medusae.

    Caput medusae

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    4.Collateral circulation through the portal-

    systemic communications formshaemorrhoids(piles) in the anal canal.

    It may be responsible forrepeated

    bleeding per rectum.

    Haemorrhoids in anal canal

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