lower your viral load. and make undetectable a possibility ... · a possibility again. if you have...

Ask your healthcare provider about TROGARZO® A first in HIV-1 treatment

LOWER YOUR VIRAL LOAD. AND MAKE UNDETECTABLE

A POSSIBILITY AGAIN.

Please see Important Safety Information throughout, and the enclosed full Prescribing Information for TROGARZO®

*Undetectable viral load is defined as fewer than 50 copies of HIV RNA per mL of blood.

MAKE UNDETECTABLE* A POSSIBILITY AGAIN.

If you have been living with HIV-1 for a while, you may know that treatment can fail you because HIV-1 can develop resistance. Once treatment fails, it may feel like getting your viral load back to undetectable* levels is out of reach.

IMAGINE REGAINING VIRAL SUPPRESSION, EVEN IF OTHER TREATMENTS HAVE FAILED YOU.

BRINGING VIRAL SUPPRESSION BACK WITHIN REACHTo combat HIV-1 when treatment fails, a regimen should be modified as soon as possible to avoid further resistance.

The most effective HIV-1 treatment regimen is one that combines 3 active antiretroviral medicines. An active antiretroviral medicine could be a new type you didn’t try before.

If treatment failure is part of your journey, you deserve to know about all of your treatment options, including TROGARZO® – HIV-1 treatment designed specifically for those with treatment failures.

Together, you and your healthcare provider can decide if TROGARZO® should be part of your treatment regimen to help keep your viral load in check.

All you have to do is ask.

IMPORTANT SAFETY INFORMATION Immune Reconstitution Inflammatory Syndrome is a side effect that can happen when you start taking HIV-1 medicines. Your immune system might get stronger and begin to fight infections that have been hidden in your body for a long time. This may result in an inflammatory response which may require further evaluation and treatment. Tell your healthcare provider right away if you experience any new symptoms after starting TROGARZO®.

Also tell your healthcare provider about all the medicines you take, including all prescription and over-the-counter medicines, vitamins, and herbal supplements.

Possible side effects of TROGARZO®

The most common side effects of TROGARZO® include:• Diarrhea • Nausea • Dizziness • Rash

TROGARZO® may cause serious side effects, including changes in your immune system.

Please see the back cover for complete safety details.

TROGARZO®, A BREAKTHROUGH IN HIV-1 TREATMENT.Given once every 2 weeks, TROGARZO® is the first and only long-acting antiviral against HIV-1 – a breakthrough in a class of its own.

TROGARZO® works differently. Unlike antiretroviral medicines that aim to prevent HIV-1 from multiplying inside the immune system’s T-cells, it is a biologic - an antibody bioengineered specifically to protect your T-cells from the virus. TROGARZO® binds to the T-cell’s surface to block HIV-1 from entering.

THIS CAN HELP PROTECT THE T-CELL AND REDUCE OR "LIGHTEN" YOUR VIRAL LOAD

WHAT IS TROGARZO®?TROGARZO® is a medicine that’s used in combination with other antiretroviral medicines to treat HIV-1 infection in adults who:

+ +Have been on different

HIV-1 treatment regimens in the past, and

Have HIV-1 that is resistant to antiretroviral

medicines, and

Are currently on an HIV-1 treatment

regimen that is failing







TROGARZO® is not a daily pill. It’s an intravenous (IV) infusion given over 15–30 minutes every 2 weeks.

Infusion appointments can be a great time to ask any questions you may have about your treatment, or simply keep in touch with your care provider.

Given once every 2 weeks

Appointments arranged by your personal Patient

Care coordinator

Given by a healthcare provider at home, an infusion

center or office

LIGHTEN THE VIRAL LOADIn a clinical study, TROGARZO® was proven to have a significant and long-lasting impact on the amount HIV-1 in the body, reducing or “lightening” viral load.

TAKEN EVERY TWO WEEKS

83% OF PATIENTS WERE ABLE TO REDUCE THEIR HIV-1 VIRAL LOAD AFTER RECEIVING A SINGLE DOSE OF TROGARZO®.

Also, studies showed that patients who reached undetectable were able to remain undetectable over time.

TROGARZO® does not interact with other drugs, so you can take it with other medications you may be taking. Be sure to discuss other medications you may be taking with your healthcare provider before taking TROGARZO®.

A PROVEN SAFETY PROFILETROGARZO® is generally well tolerated, with a low incidence of adverse reactions. Of the adverse reactions that were reported, 90% were mild or moderate in severity, including diarrhea, dizziness, nausea and rash.



YOUR THERAPY. YOUR CHOICE.LOCATIONS AVAILABLE FOR INFUSIONS

WHAT TO EXPECT WITH YOUR INFUSIONSBefore your infusion

• Ask your Patient Care coordinator if you should bring any documents (like insurance info) to your appointment

During your infusion

• Someone will monitor your therapy during the 15-30 minute infusion.

• Take the opportunity to discuss HIV-1 related topic with your care provider

After your infusion

• You’ll also be monitored afterwards for a short period of time to ensure that your body tolerates your treatment well.

INFUSION CENTER YOUR HOME YOUR HEATHCARE PROVIDER’S OFFICE

Depending on your insurance coverage, your Patient Care coordinator will arrange for your infusions to be given at a location of your choosing – at an infusion center, in your own home, or at your healthcare provider’s office. If you decide, over time, that another location would be more convenient for you, simply let them know.

You can also reach them by phone to ask any questions you may have about your treatment.







ASK YOUR HEALTHCARE PROVIDER ABOUT TROGARZO® When your HIV-1 treatment fails, it’s important to stay on top of your treatment and know all of your options. Because you deserve to know.

START THE CONVERSATION Get the conversation started with your healthcare provider to get the most from your HIV-1 treatment.

Ask:• What is my HIV-1 viral load?• What is resistance?• Do I need resistance testing?• Which classes of HIV-1 treatments am I resistant to?• What fully active agents are available to me?• Am I currently on two or three fully active agents?• How many HIV-1 treatment options do I have left?• Could I benefit from adding TROGARZO® to my treatment plan?

MEET THERA PATIENT SUPPORT™ We’re here to help make your journey as smooth as possible and answer any questions you may have.

Once TROGARZO® becomes a part of your regimen, you’ll receive a welcome call from your dedicated Patient care coordinator.

We can also assist with your private or government insurance coverage, including ADAP and will also assist in applying any eligible co-pay assistance.

From appointment reminders to insurance coverage assistance, and anything in between, our knowledgeable team is here to help.

LEARN MORE AT THERAPATIENTSUPPORT.COM


TROGARZO® is a registered trademark of TaiMed Biologics Inc., under license to Theratechnologies Inc. © 2019 Theratechnologies Inc. All rights reserved. 550-01-06/19

IMPORTANT SAFETY INFORMATION

Before you receive TROGARZO® (ibalizumab-uiyk)

Tell your healthcare provider about all of your medical conditions, including if you are:• Pregnant or plan to become pregnant. It is

not known if TROGARZO® may harm your unborn baby. Tell your healthcare provider if you become pregnant during treatment with TROGARZO®.

• Breastfeeding or plan to breastfeed. Do not breastfeed if you are receiving TROGARZO® or have HIV-1. Talk with your healthcare provider about the best way to feed your baby during treatment.





Immune Reconstitution Inflammatory Syndrome is a side effect that can happen when you start taking HIV medicines. Your immune system might get stronger and begin to fight infections that have been hidden in your body for a long time. This may result in an inflammatory response which may require further evaluation and treatment. Tell your healthcare provider right away if you experience any new symptoms after starting TROGARZO®.

Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of TROGARZO®.

For more information or medical advice about side effects, ask your healthcare provider. You may report side effects to the FDA at 1-800-FDA-1088 or the THERA patient support™ program at 1-833-238-4372.

FOR MORE INFORMATION ABOUT TROGARZO® GO TO TROGARZO.COM

If you have any questions, call the THERA patient support™ program at 1-833-23-THERA (1-833-238-4372),

Monday–Friday, 8AM–8PM ET.

THERA supportTMpatient

ASK YOUR HEALTHCARE PROVIDER ABOUT TROGARZO® When your HIV-1 treatment fails, it’s important to stay on top of your treatment and know all of your options. Because you deserve to know.

lower your viral load. and make undetectable a possibility ... · a possibility again. if you have...

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