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    LOWER RESPIRATORY

    TRACT INFECTIONS

    MANALI H SOLANKIF.Y.M.SC.NURSING

    J G COLLEGE OF NURSING

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    TERMINOLOGY:

    BRONCHITIS

    PNEUMONIA

    PULMONARY TUBERCULOSIS

    HAEMOPTISIS

    HAEMATEMESIS

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    INTRODUCTION

    Lower respiratory tract infection

    comprises an array of diseases ranging

    from bronchitis to pneumonia.

    Non-pneumonic LRTI is described as

    lower respiratory tract symptoms in a

    patient who has no history of these or anyother chest signs related with infection,

    by all of the major respiratory viral

    groups.

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    ANATOMY AND PHYSIOLOGY

    OF RESPIRATORY SYSTEM

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    BRONCHITIS:

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    DEFINITION:

    Bronchitis is an inflammationof the bronchial tubes, the

    airways that carry air to lungs

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    TYPES:

    There are two types of bronchitis

    1.Acute bronchitis2.Chronic bronchitis

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    Acute bronchitis

    Acute (i.e. recent onset) bronchitis is

    an inflammation of the lowerrespiratory passages (bronchi).

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    Chronic bronchitis

    Chronic bronchitis is defined

    as a cough that occurs every

    day with sputum productionthat lasts for at least 3

    months, two years in a row.

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    CAUSES:

    Viral infection that causes the

    inner lining of the bronchial tubes

    to become inflamed and undergothe changes that occur with any

    inflammation in the body.

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    Bacteria can also cause bronchitis (a

    few examples include, Mycoplasma,

    Pneumococcus, Klebsiella,Haemophilus).

    Chemical irritants (for example,

    tobacco smoke, gastric reflux

    solvents) can cause acute bronchitis

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    RISK FACTORS:

    Smokers

    People who are exposed to a lot of

    second-hand smoke

    People with weakened immune systems

    The elderly and infants

    People with gastroesophageal refluxdisease (GERD)

    Those who are exposed to irritants at work

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    SIGN AND SYMPTOMS

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    Coughing

    Production of clear, white, yellow,grey, or green mucus (sputum)

    Shortness of breath

    Wheezing

    Fatigue

    Fever and chills Chest pain or discomfort

    Blocked or runny nose

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    ASSESSMENT AND

    DIAGNOSTIC FINDINGS

    Patient history

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    Physical examination

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    Pulmonary function tests

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    Spirometry

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    Peak flow monitoring (PFM)

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    Pulse oximetry

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    X-ray

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    MEDICAL MANAGEMENT:

    Ibuprofen or acetaminophen

    Cough suppressantE.g. Delsym, Robitussin Cough,

    Dextromethorphan

    Steroid medicine

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    Nasal decongestants: like Naphazoline,

    Phenylephrine Oxymetazoline ,

    Propylhexedrine, Phenylpropanolamine

    Antiviral medicine

    Like amantadine, oseltamivir

    Antibiotics: Antibiotics may be given to

    help treat or prevent an infection caused

    by bacteria

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    PREVENTION:

    Avoid alcohol

    Avoid irritants in the air

    Drink more liquids Get more rest

    Eat healthy foods

    Use a humidifier or vaporizer

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    Avoiding people who are sick with colds or

    the flu

    Getting a yearly flu vaccine

    Getting a pneumonia vaccine (especially

    for those over 60 years of age)

    Washing hands regularly

    Avoiding cold, damp locations or areas

    with a lot of air pollution

    Wearing a mask around people who are

    coughing and sneezing

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    NURSING MANAGEMENT

    Monitor for adverse effects of bronchodilators-

    tremulousness, tachycardia, cardiac

    arrhythmias, central nervous system stimulation,

    hypertension. Monitor oxygen saturation at rest and with

    activity.

    Eliminate all pulmonary irritants, particularly

    cigarette smoke. Smoking cessation usually

    reduces pulmonary irritation, sputum production,

    and cough. Keep the patients room as dust-free

    as possible.

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    Use postural drainage positions to help

    clear secretions responsible for airway

    obstruction. Teach controlled coughing.

    Encourage high level of fluid intake (8 to

    10 glasses; 2 to 2.5 L daily) within level ofcardiac reserve.

    Give inhalations of nebulized saline to

    humidify bronchial tree and liquefysputum. Add moisture (humidifier,

    vaporizer) to indoor air.

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    Avoid dairy products if these increase

    sputum production.

    Encourage the patient to assumecomfortable position to decrease

    dyspnoea.

    Use pursed lip breathing at intervals andduring periods of dyspnoea to control rate

    and depth of respiration and improve

    respiratory muscle coordination.

    Discuss and demonstrates relaxation

    exercises to reduce stress, tension, and

    anxiety.

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    Encourage frequent small meals if the patient is

    dyspnoeic; en a small increase in abdominal

    contents may press on diaphragm and impede

    breathing.

    Offer liquid nutritional supplements to improve

    caloric intake and counteract weight loss.

    Avoid foods producing abdominal discomfort.

    Encourage use of portable oxygen system for

    ambulation for patients with hypoxemia and

    marked disability.

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    PNEUMONIA

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    DEFINITION

    Pneumonia is an inflammation of the

    lungs caused by bacteria, viruses, or

    chemical irritants. It is a seriousinfection or inflammation in which the

    air sacs fill with pus and other liquid.

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    TYPES:

    Bacterial pneumonia

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    Viral pneumonia

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    Mycoplasma pneumonia

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    Aspiration pneumonia

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    Fungal pneumonia

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    Hospital acquired pneumonia

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    Community acquired pneumonia

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    CAUSES:

    Bacterial

    Viral

    Fungal

    Nosocomial and others

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    RISK FACTORS

    Smoke.

    Abuse alcohol.

    Have other medical conditions, such as

    chronic obstructive pulmonary disease

    (COPD), emphysema, asthma, or

    HIV/AIDS.

    Are younger than 1 year of age or older

    than 65

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    Have a weakened or impaired immune system.

    Take medicines for gastroesophageal refluxdisease (GERD).

    Have recently recovered from a cold or influenza

    infection.

    Are malnourished.

    Have been recently hospitalized in an intensive

    care unit.

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    Have been exposed to certain

    chemicals or pollutants. Are Native Alaskan or certain Native

    American ethnicity.

    Have any increased risk of breathingmucus or saliva from the nose or

    mouth, liquids, or food from the

    stomach into the lungs.

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    SIGN AND SYMPTOMS

    Cough

    Rusty or green mucus (sputum) coughed up from lungs

    Fever

    Fast breathing and shortness of breath Shaking chills

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    Chest pain that usually worsens when

    taking a deep breath (pleuritic pain)

    Fast heartbeat

    Fatigue and feeling very weak

    Nausea and vomiting

    Diarrhoea

    Sweating

    Headache

    Muscle pain

    ASSESSMENT AND DIAGNOSTIC

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    ASSESSMENT AND DIAGNOSTIC

    FINDINGS

    Chest x ray

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    Blood tests

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    Sputum culture

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    Pulse oximetry

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    chest CT scan

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    bronchoscopy

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    Pleural fluid culture

    Th t i

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    Thoracentesis

    MEDICAL MANAGEMENT

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    MEDICAL MANAGEMENT

    MACROLIDES

    TETRACYCLINES

    FLUOROQUINOLONES

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    SURGICAL MANAGEMENT

    Thoracotomy

    Chest Tubes

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    Chest Tubes

    COMPLICATIONS OF PNEUMONIA:

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    COMPLICATIONS OF PNEUMONIA:

    Abscesses

    Respiratory Failure

    Bacteraemia Empyema and Pleural Effusions

    Collapsed Lung

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    NURSING MANAGEMENT

    Maintain a patent airway and adequate

    oxygenation.

    Obtain sputum specimens as needed.

    Use suction if the patient cant produce a

    specimen

    Provide a high calorie, high protein diet of

    soft foods

    T t i ti d i

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    To prevent aspiration during

    nasogastric tube feedings, check the

    position of tube, and administerfeedings slowly.

    To control the spread of infection,

    dispose secretions properly.

    Provide a quiet, calm environment,

    with frequent rest periods.

    M it th ti t ABG l l

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    Monitor the patients ABG levels,

    especially if hes hypoxic.

    Assess the patients respiratory status.Auscultate breath sounds at least every 4

    hours.

    Monitor fluid and intake output. Evaluate the effectiveness of administered

    medications.

    Explain all procedures to the patient andfamily

    PREVENTION

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    PREVENTION

    Good Hygiene and Preventing

    Transmission

    Changing Hospital Practices

    Vaccines

    Viral Influenza Vaccines (Flu Shot)

    Pneumococcal Vaccines Vitamins

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    PULMONARY TUBERCULOSIS

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    DEFINITION

    Pulmonary tuberculosis is a chronic

    infectious inflammation of the lung, as

    well as a special pneumonia.

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    CAUSES AND RISK FACTORS

    Alcoholism

    IV drug abuse

    Crowded living conditions Homelessness

    Poverty

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    Immigration from certain countries

    Low body weight

    Certain medical treatments (such ascorticosteroid treatment or organ

    transplants)

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    SIGN AND SYMPTOMS

    Cough (usually cough up mucus)

    Coughing up blood

    Excessive sweating, especially at night

    Fatigue

    Fever

    Unintentional weight loss

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    Other symptoms that may occur with

    this disease: Breathing difficulty

    Chest pain

    Wheezing

    ASSESSMENT AND DIAGNOSTIC

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    ASSESSMENT AND DIAGNOSTIC

    FINDINGS

    Biopsy of the affected tissue (rare)

    Bronchoscopy

    Chest CT scan

    Chest x-ray

    Interferon-gamma blood test such as the

    QFT-Gold test to test for TB infection

    Sputum examination and cultures

    Thoracentesis

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    Tuberculin skin test

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    MEDICAL MANAGEMENT

    1st line drugs

    DRUG DOSEIsoniazide (INH) 300 mg/dayRifampicin 600 mg/dayPyrazinamide 1500 mg/day 25 mg/kg/dayEthambutol 1200 mg/day 15-25

    mg/kg/dayStreptomycin 0.751gm/day 25 mg/kg/day

    2nd line drugs

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    2nd line drugs

    Amikacin (AG) 15 mg/kg/dayAminosalicylic acid 8-12 gm/dayCapreomycin 15 mg/kg/dayCiprofloxacin

    1500 mg/day (divided)

    Clofazimine 200 mg/dayCycloserine 500-1000 mg/day

    (divided)Ethionamide 500-750 mg/dayLevofloxacin 500 mg/dayRifabutin 300 mg/day

    Current recommended treatment for

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    Cu e t eco e ded t eat e t o

    pulmonary TB has three regimens

    6 Month Regimenvirtually 100% effective,

    more expensive. (usually only used inpulmonary TB)

    Fi t 2 th

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    First 2 months

    DRUG DOSEIsoniazide300mg 1 tablet daily (300mg)Rifampicin300mg 2 tablets daily (600mg)Pyrazinamide

    500mg 3 tablets daily (1500mg)

    Ethambutol400mg 3 tablets daily (1200mg)

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    Next 4 months

    DRUG DOSEIsoniazide300mg 1 tablet daily (300mg)Rifampicin300mg 2 tablets daily (600mg)Pyridoxine10mg 1 tablet daily (10mg) for 6

    months

    9 M th R i

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    9 Months Regimen

    First 2 months

    DRUG DOSEIsoniazide300mg 1 tablet daily (300mg)Rifampicin

    300mg

    2 tablets daily (600mg)

    Ethambutol400mg 3 tablets daily(1200mg)

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    Next 7 months

    DRUG DOSEIsoniazide300mg 1 tablet daily (300mg)Rifampicin300mg 2 tablets daily

    (600mg)Pyridoxine10mg 1 tablet daily (10mg)

    12 Months Regimen

    inexpensive

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    and reasonably effective.

    Regimen 1effectiveness is nearly 100%

    InjectionStreptomycin 1gm (IM)TwiceWeeklyTablet Isoniazide 15 mg/kg/dayTablet Pyridoxine 1 tablet of 10mg daily

    Regimen 2

    very cheap,

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    effectiveness is 80-90%

    Isoniazide 1 tablet daily(300mg)

    Tablet Thiocetazone 1 tablet daily (150mg)Pyridoxine 1 tablet daily (10mg)

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    Prophylactic Dose

    Isoniazide is indicated for the prophylacticuse of TB, the dose is 300mg/day

    (5mg/kg/day) or 900mg twice weekly for 6

    months in most cases and 12 months incase of immuno-compromised patients

    ADVERSE EFFECT OF DRUGS

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    ADVERSE EFFECT OF DRUGS

    Isoniazide Peripheral NeuropathyRifampicin Cholestatic jaundice +

    renal toxicity + Flu like

    syndromePyrazinamide Hepatotoxicity + Hyper-

    UricaemiaEthambutol Retinobulbar optic neuritis

    Prevention

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    DIETARY MANAGEMENT

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    DIETARY MANAGEMENT

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    NURSING MANAGEMENT

    Ineffective Airway Clearance may berelated to excessive, thickened mucous

    secretions, possibly evidenced by

    presence of rhonchi, tachypnea, andineffective cough.

    Acute pain related to localizedinflammation and persistent cough.

    Imbalance nutrition less than body

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    Imbalance nutrition less than body

    requirement related to frequent cough,

    anorexia and fatigue.

    Risk for infection related to inadequate

    primary defences and decreased cilliaryaction

    Anxiety related to outcome of diseases asevidenced by poor concentration on work,

    isolation from others, rude behaviour

    Activity Intolerance related to

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    Activity Intolerance related to

    imbalance between O2 supply and

    demand, possibly evidenced byreports of fatigue, dyspnoea, and

    abnormal vital sign response to

    activity.

    Knowledge deficit regarding thetreatment modalities and prognosis

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    ABSTRACT

    Lower respiratory tract infection and rapidexpansion of an abdominal aortic

    aneurysm: a case report

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    SUMMARY:

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    BIBLIOGRAPHY:

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