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MILLIPLEX Analyst Luminex TM FLEXMAP 3D LX 200 NEW! MAGPIX MILLIPLEX ® MAP Your Source for: Luminex ® xMAP ® Technology

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As a Luminex partner, Millipore is a distributor of the entire Luminex portfolio of instruments, including the LX 200™, FLEXMAP™ 3D and the MAGPIX® platforms. Millipore offers a powerful combination software package for data acquisition with the xPONENT® software and data analysis with MILLIPLEX Analyst; enabling you to manage, track and analyze your multiplex assays so you can focus your time on what’s most important—advancing your research.We were there at the beginning to help validate Luminex as the standard of multiplexing. And our ongoing dedication and experience in this technology enable you to gain more information faster, without compromising reliability.

TRANSCRIPT

Page 1: Luminex xMAP Technology

MILLIPLEXAnalyst

®

Luminex

TM

TM

FLEXMA

P 3D

LX 20

0

NEW

! MA

GPIX

MILLIPLEX® MAPYour Source for: Luminex® xMAP® Technology

Page 2: Luminex xMAP Technology

2

NOW EVERYTHING YOU NEED—ALL IN ONE PLACE• Millipore offers MILLIPLEX Analyst software, a data

analysis package to help you do your best work with

increased speed and efficiency.

• The Luminex platform and the latest xPONENT software

is designed to help you manage and track all of your

multiplex assays—spend less time running your assays

and more time advancing your research.

• Benefit from the ability to simultaneously quantitate 1 up

to potentially 500 analytes in a single sample, saving you

time, money and precious sample volume.

• We offer the broadest range of multiplex analytes for the

Luminex xMAP platform to meet your precise needs.

• Advance your multiplexing research at Millipore—all the

tools you need including kits, instrumentation, software

and service.

HOW xMAP TECHNOLOGY WORKSThe Luminex system is the combination of three core

xMAP technologies:

• xMAP microspheres, a family of 80 - 500 fluorescently

dye’d 5.6 μm polystyrene or 6.45 magnetic microspheres

that act as both the identifier and the solid surface to

build the assay.

• The Luminex analyzer, a flow cytometry-based

instrument that integrates key xMAP detection

components, such as lasers, optics, advanced fluidics and

high-speed digital signal processors.

• xPONENT software, designed for template-based data

acquisition that offers robust data regression analysis.

The rapidly growing knowledge base in drug discovery

and protein research has placed increased pressure on

researchers to quickly gain a greater understanding of

protein-protein interactions, cell signaling pathways and

markers of metabolic processes. Increasingly, this

information is difficult or impractical to obtain using

traditional “singleplex” protein detection methods, such as

ELISA or Western blotting.

By enabling you to differentiate between up to 500

analytes in each sample, xMAP technology lets

you obtain multiple results for fast, flexible, affordable

and high throughput biological testing technology. What’s

more, the open-architecture xMAP technology enables

multiplexing of many types of bioassays, reducing time,

labor and costs over traditional methods.

xMAP Technology offers many advantages compared with other immunoassay products:• Speed/High Throughput: Simultaneously measure the

concentration of a large number of different

analytes, allowing you to do more faster, gaining early

and comprehensive data so critical to your work.

• Accuracy: xMAP technology generates real-time

analysis and accurate quantification of the

biological interactions.

• Reproducibility: High-volume production of xMAP

microspheres allows assay standardization that

solid-phased flat arrays cannot provide.

• Low Sample Volume: With minimal hands-on time, you

can screen more than 40 analytes in a single sample

using as little as 25 μL or less.

Millipore, the industry’s original Luminex

thought leader, offers you the power of

MILLIPLEX map multiplex immunodetection

kits and reagents for use with Luminex xMAP

technology—one of the fastest growing and

most respected multiplex technologies for

biomarker screening and analysis in protein

research.

As a Luminex partner, Millipore is a distributor of the entire

Luminex portfolio of instruments, including the

LX 200™, FLEXMAP™ 3D and the MAGPIX® platforms. Millipore

offers a powerful combination software package for data

acquisition with the xPONENT® software and data analysis

with MILLIPLEX Analyst; enabling you to manage, track and

analyze your multiplex assays so you can focus your time

on what’s most important—advancing your research.

We were there at the beginning to help validate

Luminex as the standard of multiplexing. And our ongoing

dedication and experience in this technology enable you

to gain more information faster, without compromising

reliability.

Page 3: Luminex xMAP Technology

3

Luminex 200 and Luminex XYP™The Luminex 200 system is a compact analyzer that

performs up to 100 immunoassays simultaneously using a

single drop of fluid, therefore requiring very small samples

when compared with other testing technologies. This

system utilizes version 3.1 xPONENT of the xMAP technology

operating system.

The Luminex XY Platform (Luminex XYP) complements

the Luminex 100 and 200 systems by automating the

sequential positioning of each well of a microtiter plate.

This enables you to perform a total of up to 9,600

unattended tests per plate in less than one hour.

FLEXMAP 3DThe FLEXMAP 3D system makes it possible to multiplex up

to 500 analytes through the combination of differentially

dyed fluorescent microsphere sets and an innovative

instrument design. Features such as automated probe height

adjustment, simplified routine maintenance operations and

an intuitive software interface make FLEXMAP 3D a flexible

and user-friendly multiplexing platform capable of performing

a variety of protein and nucleic acid applications. The new

xPONENT 4.0 software controls the FLEXMAP 3D system

and offers interfacing options for laboratory information

systems (LIS) as well as automation.

Millipore offers the full line of multiplexing instruments from Luminex

to meet all of your multiplexing needs.

Luminex Instruments

The total system includes the Luminex 200 instrument, the Luminex XY plate handling platform and the Luminex SD sheath fluid delivery system and 3.1 xPONENT and MILLIPLEX Analyst software.

TM

The high throughput, high multiplexing FLEXMAP 3D system enables scientists to simultaneously perform up to 500 tests on a single sample.

FLEXMAP 3D System Highlights

• Higher throughput with up to 500 analytes per well

The new bead set features three internal dyes.

Monitoring the relative intensity of the three signals

enables the system to discriminate up to 500 different

microspheres for even more multiplexing options.

• Enhanced pipetting for fast turnaround time

Run up to 48,000 analytes in less than one hour—it’s

possible with dual sample fluidics paths and increased

syringe injection speed.

• Works with 96- and 384-well plates

Enjoy the flexibility of sample number and volume

flexibility and increased throughput. The sample plate

heating control also enables the user to run thermally

sensitive applications such as nucleic acids.

• Automation/LIS compatible

The new xPONENT 4.0 software offers interfacing

options for laboratory information systems (LIS) as

well as automation. An optional swivel base for

the system further simplifies integration with

third-party liquid handlers.

• Simplified maintenance

The FLEXMAP 3D system has multiple features

allowing walk-away start-up, shutdown, maintenance

operations and greatly enhances usability for high

throughput screening (HTS) applications.

Page 4: Luminex xMAP Technology

4

Advantages:• Easy-to-use, magnetic bead-based technology

• Simultaneously measure up to 50 analytes in as little as 25 μL of sample

• Small footprint – saves space on your lab bench

• Portable – easily moves from bench to bench, or lab to lab, self installed

• Lower-cost platform

• More than 25 MILLIPLEX mag Panels – the largest offering of magnetic bead immunoassay panels for

metabolic disease, inflammation, toxicity, neuroscience, and cell signaling research

MAGPIX vs. LUMINEX 200Luminex instrument comparison dataStandard curve for two representative analytes within the MILLIPLEX mag (magnetic) Human Metabolic Panel

100,000

MFI

s

MFI

s

Luminex 200MAGPIX

C-Peptide

10,000

1,000

100

1010 100 1,000

Standard (pg/mL)

10,000 100,000

10,000

Luminex 200MAGPIX

Glucagon

1,000

10010 100 1,000

Standard (pg/mL)

10,000

Introducing: MAGPIX InstrumentThe new wave in multiplexing

You’ll make breakthrough discoveries faster when you

perform multiple, quantitative immunoassays using a single

sample, revealing complex networks and complete systems in

a single experiment.

Millipore’s new MAGPIX instrumentation, combined

with our MILLIPLEX mag magnetic bead-based multi-

analyte panels, analysis software, and technical support,

provides a complete solution for rapid, accurate biomarker

quantification.

Accelerate your research at a price you can

afford using xMAP technology you trust. The

new MAGPIX instrument offers your lab the

benefits of multiplexing at a more compact size

and price.

The MAGPIX innovative design is based on CCD imaging technology, creates a compact, more robust system. Streamlined start-up and shut-down protocols and minimal maintenance requirements make the system easy to operate and maintain.

Page 5: Luminex xMAP Technology

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Instrument MAGPIX Luminex 100/200 FLEXMAP 3D

Software xPONENT 4.1 xPONENT 3.1 xPONENT 4.0

Optic LED/ CCD Camera Lasers/ APDs/ PMTs Lasers/ APDs/ PMTs

Hardware Fluorescent Imager Flow Cytometry based Flow Cytometry based

Bead Compatibility Magnetic Magnetic and non-Magnetic Magnetic and non-Magnetic

Multiplex Capacity 50 100 (80 for MagPlex) 500

Read Time ~ 60 mins/96 well plate ~40 mins/96well plate ~20 mins/96well plate

Applications Protein/ Nucleic Acid Protein/ Nucleic Acid Protein/ Nucleic Acid

Dynamic Range 3.5 logs 3.5 logs 4.5 logs

Microtiter Plate 96 well 96 well 96 well & 384 well

Footprint including PC (linear bench space)

64.8 cm (24”) 80.0 cm (32”) 64.8 cm (24”)

Weight (Analyzer) 17.5 kg (38.5 lbs) 49 kg (113 lbs) 77.1 kg (170 lbs)

Specifications

LX 200 & FLEXMAP 3D Flow Cytometry-Based Analysis

MAGPIX LED/Image-Based Analysis

Magneticcapture

Interrogate label with green laser (525 nm)

Quantify Binding Events

Interrogate label with green LED (525 nm)

Identify and quantify with CCD imager

Interrogate bead with red LED (635 nm)

Identify bead region based on internal dye concentrations

Interrogate bead with red laser (635 nm)

Sheath Fluid

CHOOSE THE INSTRUMENT THAT’S RIGHT FOR YOU

MAGPIX takes advantage of a new lighting and detection mechanism to reduce costs and improve reliability. Unlike

flow cytometry which leverages the physics of fluid flow to align beads single file through a cuvette, where they

can be illuminated with higher cost lasers, MAGPIX flows beads with considerably less fluid volume into a chamber.

There they are held in a monolayer with a magnet. LEDs are focused on the chamber to illuminate the beads. In

flow cytometry, the fluorescence of the beads is measured with a Photo Multiplier Tube. MAGPIX, takes an image

of the beads in the chamber with a CCD camera. Image processing algorithms are run to deliver the assay results.

MAGPIX xMAP DETECTION COMPARISON

Page 6: Luminex xMAP Technology

6

Millipore offers a low cost alternative to automated washing

of MILLIPLEX mag Immunoassays without loss in assay

performance. The hand-held magnetic separator allows the

liquid contents of the 96-well plate to be removed by simply

decanting or “flicking” the contents into a sink and blotting off

the remainder on a paper towel. Magnetic beads are securely

held to the sides by 9 magnets surrounding each well.

• Top magnetic frame

is white polycarbonate, with a

corrosion resistant steel plate

underneath, all mounted to a

polypropylene base

• Adjustable clip system holds

a wide variety of microplates

to the separator block

• O-Ring on Base Plate facilitates gripping for all sizes of hands

Millipore, in partnership with BioTek, is now offering the

newest ELx405 enhancement: full plate biomagnetic

separation, washing and vacuum filtration for magnetic

bead assays. As your source for multiplexing reagents,

Millipore offers a complete selection of MILLIPLEX map

kits, instruments, software, and service, in addition to the

new magnetic bead kits and the BioTek washer, hand-held

magnetic separation and multi-screen vacuum manifold.

BioTek’s® New Elx405 Microplate Washer For 96-Well Biomagnetic Separation

Handheld Magnetic Separator Block for 96-Well Flat Bottom or Conical Well Plates

Washing Solutions For Magnetic & Non-Magnetic Bead Assays

BioTek Advantage• Assays – Magnetic Beads, MILLIPLEX map Multiplex Assays

and ELISA

• Microplate Type – 96-well, standard height and low profile

• Magnet – optimized for flat-bottom microplates,

incorporated into carrier and removable for non-magnetic

washing

• Residual Volume - ≤ 2 μL/well and vacuum filtration,

Average increased weight of the plate is ≤ 1.2 grams

after dispensing 300 μL of deionized water per well into a

Millipore MSHVN4450 96-well 0.45 μm plate and vacuum

aspirated for 30 seconds at a vent diameter 0.047” (no

plug) and blotted on a paper towel

• Manifold Type – 96-well washing (96 tube (8 x 12) manifold

• Washing Speed - <30 seconds, 3 aspirate/dispense cycles,

300 μL/well and final aspirate

MultiScreen®HTS Vacuum Manifold

Developed for Maximum Versatility• Configurations for deep well or standard receiver plates

• ANSI/SBS compliant footprint allows for

easy robotic deck integration

• Solvent-resistant

The MultiScreenHTS

vacuum manifold is ideal for multiwell

filter plate applications in both manual and automated

laboratory environments. The manifold supports a wide

variety of MultiScreen platforms, including 96-well and 384-

well filter plates for bioassays, and deep well Solvinert™

filter plates for sample preparation. Built with flexibility in

mind, it can be easily configured to support applications

that require flow to waste as well as analyte collection.

As part of the standard equipment, you receive a vacuum

pressure indicator allowing you to set and reliably measure

vacuum pressure. Controls include an external on/off

valve and a vacuum level adjustment valve for optimizing

filtration performance. You also have the choice of vacuum

source options, including the use of a Millipore vacuum

pump, available separately, or house vacuum.

For more information go online at:

www.millipore.com/catalogue/module/C9206.

BioTek’s new ELx405 Microplate Washer for 96-Well Biomagnetic Sepa-ration offers the convenience of full plate washing for magnetic bead assays as well as standard ELISA’s. The ELx405 Magnetic Bead Washer uses high-energy neodymium iron boron magnets for rapid separation of micrometer and nanometer beads with superior retention.

Page 7: Luminex xMAP Technology

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MILLIPLEX ANALYST MULTIPLEX DATA ANALYSTS SOFTWARE FOR THE LUMINEX XPONENT SYSTEM—YOUR PERFECT ANALYTIC SOLUTIONMILLIPLEX Analyst software provides a whole new level of

data analysis. Even Microsoft Excel® or text files with large

data sets are seamlessly imported into MILLIPLEX Analyst

software, and your results are calculated in seconds with

a quick plate setup and very user-friendly features. This

data analysis software package incorporates tried-and-true

algorithms to provide the performance you need, even when

faced with the most challenging multiplexing data sets. Also

included are report formats and enhanced presentation

features that you’ve requested to display your information

clearly and accurately.

MILLIPLEX Analyst Software Provides a Superior Data Analysis Solution:• Simple integration with the Luminex xPONENT System

– Import Microsoft Excel or text files

– User-friendly plate setup features let you work with

speed and efficiency

• Benefit from the ability to calculate your results in

seconds with large data sets

• Unique algorithms work on even the most challenging

data sets, giving you the performance you need for

complex analysis

• Get the report formats and enhanced presentation

features you’ve requested—plus, many options for

advanced users

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Luminex xPonent and MILLIPLEX Analyst SoftwareMillipore offers the complete software solution for your multiplexing assays with xPONENT for data

acquisition and MILLIPLEX Analyst for data analysis.

xPONENT’s many features create an instrument platform

that steps up your research by reducing time spent running

assays, increasing walk-away time and the ability to automate.

MILLIPLEX Analyst seamlessly integrates with xPONENT

to quickly analyze with unique algorithms even the largest

data sets. Reports are easily created in multiple formats

for enhanced presentation. This combination generates the

information for your next big discovery.

MILLIPLEX map STAT Panel: Daudi, HepG2 and HeLa Cell LinesData generated with the MILLIPLEX Analyst and illustrated with the 3D tool for reports powered by VigeneTech® software exclusively for Millipore.

Page 8: Luminex xMAP Technology

8

Spend Less Time Running Your Assays and More Time Advancing Your Research:• Calibration kit, verification kit and a new Automated

Maintenance Plate (AMP) included; enabling automation

of daily system maintenance operations; increasing

walk-away time; and providing a significant time savings

• Intuitive graphical user interface for simplified workflow

• Modules available include LIS integration which enables

bidirectional interface connectivity via ASTM protocol

• Assay-specific reporter gain levels feature allows you to

optimize assay sensitivity by using gain adjustment

• Flexible data archiving lets you archive by batch,

protocol, kits or lots

• XML data output provides easy-to-capture data

regression and more system log information

• Real-time system status indication on the main menu

provides immediate updates all from the same screen

• Plate layout report reduces errors, allowing you to print

out and use as a guide when pipetting

• Compatible with magnetic bead (MagPlex bead) assays

Luminex has designed xPONENT software solutions based

on suggestions from our valued customers. Now you

can customize your own software solution by adding

individual modules. (See ordering information for

additional software modules.)

Easy Integration:• PDF and Microsoft Excel export compatible

• Optional 21 CFR part 11 compilant module available

• Compatible with Luminex 1.7 and 2.3 file formats

• Import data in Microsoft Excel/text formats from

Bio-Plex®, Miraibio™, and other Luminex software programs

Powerful Analysis:• 5-PL, 4-PL, cubic spline, and linear curve-fitting

capabilities

• Multiplate analysis capabilities

• Options for QC input and acceptance range reporting

• Up to 4 standard report options with enhanced graphing

for standards curves as well as sample points

• Standard curve fitting parameters and reporting for

R2, CV, minDC, maxDC, and % recovery

• Sample reporting to include concentration and

standard deviations

• 2D and 3D bar chart displays

• Qualitative data analysis as well as reference/

normalization capabilities

LUMINEX XPONENT SOFTWARE—SYSTEM CONTROL AT YOUR FINGERTIPSManage and track all your multiplex assays with the new

xPONENT system control software. Millipore is one of the

few Luminex partners to offer this intuitive new system.

xPONENT software brings the power of integration

and automation to your laboratory to improve workflow

efficiency. This system control software combines ease

of use with the flexibility to perform both protein and nucleic

acid testing on one system. It’s also compatible with magnetic

bead (MagPlex™ beads) assays and will be moving forward

with compatible future instrument platforms.

Page 9: Luminex xMAP Technology

9

Description Qty/Pk Catalogue No.

Luminex 200 3.1 xPONENT System w/MILLLIPLEX Analyst EA 40-013

xPONENT 3.1 Option: 21CFR Part 11 EA 40-270

xPONENT 3.1 Option: Automation Module EA 40-271

xPONENT 3.1 Option: LIS/LIMS Module EA 40-272

xPONENT 3.1 Option: Basic Security Module EA 40-273

xPONENT 3.1 Option: Extra Seat Licenses (3) EA 40-274

Luminex 200 Calibration Kit (25 doses) EA 40-275

Luminex 200 Performance Verfication Kit (25 doses) EA 40-276

Automated Maintenance Plate EA 40-277

xPONENT Option: New PC EA 40-261

xPONENT Option:Touch Screen Monitor EA 40-262

xPONENT Option: Flat Panel Monitor EA 40-263

FLEXMAP 3D with MILLIPLEX Analyst EA 40-022

xPONENT Option: 21CFR Part 11 for FLEXMAP 3D EA 40-023

xPONENT Option: Automation Module for FLEXMAP 3D EA 40-024

xPONENT Option: LIS/LIMS Module for FLEXMAP 3D EA 40-025

xPONENT Option: Basic Security Module for FLEXMAP3D EA 40-041

xPONENT Option: Extra Seat Licenses (3) for FLEXMAP 3D EA 40-026

Swivel Base for FLEXMAP 3D EA 40-027

FLEXMAP 3D Calibration Kit EA 40-028

FLEXMAP 3D Performance Verification Kit EA 40-029

MILLIPLEX Analyst Base Package EA 40-265

MILLIPLEX Analyst Extra Seat License EA 40-266

MILLIPLEX Analyst 21 CFR Part 11 EA 40-267

MAGPIX xPONENT 4.1 System with MILLIPLEX Analyst Single Seat EA 40-043

xPONENT 4.1 Option: Basic Security Module EA 40-044

xPONENT 4.1 Option: 21CFR Part 11 EA 40-045

xPONENT 4.1 Option: Automation Module EA 40-046

xPONENT 4.1 Option: LIS/LIMS Module EA 40-047

xPONENT 4.1 Option: Extra Seat Module (3) EA 40-048

MAGPIX Calibration Kit (25 doses) EA 40-049

MAGPIX Performance Verfication Kit (25 doses) EA 40-050

BioTek Magnetic 96 Well Plate Washer, 110 V EA 40-015

BioTek Magnetic/Vacuum Filtration 96 Well Plate Washer, 110 V EA 40-034

BioTek Complete Accessory pack (110 V) EA 40-016

BioTek Magnetic 96 Well Plate Washer 220V with Schuko Power Cords EA 40-017

BioTek Magnetic 96 Well Plate Washer 220V with UK Power Cords EA 40-018

BioTek Magnetic 96 Well Plate Washer 220V with Australian Power Cords EA 40-019

BioTek Magnetic 96 Well Plate Washer 220V with Chinese Power Cords EA 40-020

BioTek Magnetic/Vacuum Filtration 96 Well Plate Washer 220V with Schuko Power Cords EA 40-036

BioTek Magnetic/Vacuum Filtration 96 Well Plate Washer 220V with UK Power Cords EA 40-037

BioTek Magnetic/Vacuum Filtration 96 Well Plate Washer 220V with Australian Power Cords EA 40-038

BioTek Magnetic/Vacuum Filtration 96 Well Plate Washer 220V with Chinese Power Cords EA 40-039

BioTek Complete Accessory Pack (220 V) EA 40-021

Hand-Held Magnetic Separation Block for 96-well Plate EA 40-285

Luminex Instruments and Software

Ordering Information

9

Page 10: Luminex xMAP Technology

1010

Description Qty/Pk Catalogue No.

MultiScreen HTS Vacuum Manifold Standard KitIncludes manifold base standard collar, gaskets, gasket inserts, all tubing, valves, and pressure gauge

1 MSVMHTSOO

MultiScreenHTS Vacuum Manifold

MILLIPLEX mag — Your Source for Magnetic Bead Kits

Description Catalogue No.

MAGNETIC - METABOLISM

Human Metabolic DiseaseAmylin (active) Amylin (total) C-PeptideGhrelin (active) GIP (total) GLP-1 (active) GlucagonIL-6InsulinLeptinMCP-1 Pancreatic PolypeptidePYY (total)TNFa

HMHMAG-34K

Mouse Metabolic DiseaseAmylin (active) C-PeptideGhrelin (active) GIP (total) GLP-1 (active) GlucagonIL-6InsulinLeptinMCP-1 Pancreatic PolypeptidePYY (total)ResistinTNFa

MMHMAG-44K

Rat Metabolic DiseaseAmylin (active) C-Peptide 2Ghrelin (active) GIP (total) GLP-1 (active) GlucagonIL-6InsulinLeptinMCP-1 Pancreatic PolypeptidePYY (total)TNFa

RMHMAG-84K

Canine Gut HormoneAmylin (active) Ghrelin (active) GIP (total) GLP-1 (active) GlucagonInsulinLeptinPancreatic PolypeptidePYY (total)

CGTMAG-98K

Human Liver ProteinAFPANGPTL3ANGPTL4ANGPTL6FABP1FGF-19FGF-21FGF-23HGF

HLPPMAG-57K

Description Catalogue No.

Mouse IGF Binding ProteinIGFBP1IGFBP2IGFBP3IGFBP5IGFBP6IGFBP7

MIGFBPMAG-43K

Mouse Acute Phase ProteinAdipsin AGPCROLipocalin (24P3)PTX-3SAA-3

Coming Soon

Canine PituitaryACTHBDNFFSHGHLHProlactinTSH

Coming Soon

Multi Species Steroid/Thyroid HormoneCorticosteroidEstradiolFree T3Free T4ProgesteroneTestosterone

STTH-21K

Rat PituitaryACTHBDNFFSHGHLHProlactinTSH

RPTMAG-86K

MAGNETIC - TOXICITY

Human Kidney Toxicity Panel 1 Serum SamplesKIM-1OsteopontinReninTFF-3

HKTX1MAG-38K

Human Kidney Toxicity Panel 2 Serum Samplesb-2-Microglobulin ClusterinCystatin C

HKTX2MAG-38K

Human Kidney Toxicity Panel 3 Urine SamplesKIM-1ReninTFF-3

HKTX3MAG-38K

Human Kidney Toxicity Panel 4 Urine SamplesAlbuminb-2-MicroglobulinClusterinCystatin COsteopontin

HKTX4MAG-38K

Page 11: Luminex xMAP Technology

1111

v Cannot be plexed with other cytokines in human serum/plasma samples.

Description Catalogue No.

MAGNETIC - INFLAMMATION / IMMUNOLOGY

Human Cytokine/Chemokine I IL-1aIL-1b IL-1raIL-2IL-3IL-4IL-5IL-6IL-7IL-8IL-9IL-10IL-12 (p40)IL-12 (p70)IL-13IL-15IL-17aEGFEotaxinFGF-2Fit-3 ligandFractalkineG-CSFGM-CSFGROIFNa2IFNgIP-10MCP-1MCP-3/CCL7MDC/CCL22MIP-1aMIP-1bPDGF-AAvPDGF-AB/BBvRANTESv sIL-2RasCD40LTGFaTNFaTNFbVEGF

HCYTOMAG-60K

Human Cytokine/Chemokine IIIL-16IL-20IL-21IL-23IL-28aIL-33/NF-HEV (mature)6Ckine/CCL21BCA-1/CXCL13CTACK/CCL27ENA-78/CXCL5Eotaxin-2/CCL24/MPIF-2Eotaxin-3/CCL26I-309/CCL1LIFMCP-2MCP-4MIP-1d (MIP-5/CCL15)SCFSDF-1a+b/CXCL12TARC/CCL17TPOTRAIL/TNFSF10TSLP

HCYP2MAG-62K

Human Cytokine/Chemokine IIIIL-11IL-29GCP-2/CXCL6/LIXHCC-1/CCL14avI-TAC/CXCL11LymphotactinM-CSFMIG/CXCL9MIP-3a/CCL19MIP-3b/CCL20NAP-2/CXCL7v

MCYP3MAG-74K

Description Catalogue No.

Human High Sensitivity Cytokine/ChemokineIL-1bIL-2IL-4IL-5IL-6IL-7IL-8IL-10IL-12 (p70)IL-13GM-CSFIFNgTNFa

HSCYTMAG-60SK

Mouse Cytokine/ChemokineIL-1aIL-1bIL-2IL-4IL-5IL-6IL-7IL-9IL-10IL-12 (p40)IL-12 (p70)IL-13IL-15IL-17aG-CSFGM-CSFIFNgIP-10KCMcP-1MIP-1aMIP-1bMIP-2RANTESTNFa

MCYTOMAG-70K

Rat Cytokine/ChemokineIL-1aIL-1bIL-2IL-4IL-5IL-6IL-10IL-12 (p40)IL-13IL-17aIL-18EotaxinG-CSFGM-CSFGRO-KCIFNgIP-10KCMcP-1MIP-1aRANTESTNFaVEGF

RCYTOMAG-80K

MAGNETIC - EPIQUANT CELL SIGNALING

EpiQuant™ EGFR Signaling Pathway Panel CSK (Tyr304)EGFR (Tyr1110/1125)EGFR TotalErbB3 (Tyr1197/1199/1262/1276/1298/1307)ERK 1/2 (Tyr204/187)FAK (Tyr397/407)FAK (Tyr861)FRS2 (Tyr436)Gab1 (Tyr285/307/317)Gab2 (Tyr266)Gab2 (Tyr584)Gab2 (Tyr614)HER2 (Tyr1023)HER2 (Tyr1112/1139)HER2 (Tyr1196/1221/1222)PI3Kp110 (Tyr485)PKCμ (Tyr502)PLC1 (Tyr1253)PLC2 (Tyr1197/1217)Shc (Tyr349/350)SPRY2 (Tyr55)STAT3 (Tyr705)TAF1168 (loading control)

MPEQ110MAG-110K

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