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South West Peninsula Cancer Specialty Recruitment Data from Portfolio ODP – Cut off 06/12/15TRANSCRIPT
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Lung Cancer Research Clinical Research Network
South West Peninsula
Julie CunninghamResearch Delivery Manager
Oncology / Haematology / Genetics
National Cancer Specialty Recruitment
Data from Portfolio ODP – Cut off 06/12/15
South West Peninsula Cancer Specialty Recruitment
Data from Portfolio ODP – Cut off 06/12/15
Lung Tumour Group National Perspective
Data from Portfolio ODP – Cut off 06/12/15
Lung Tumour Group National Perspective
Data from Portfolio ODP – Cut off 06/12/15
CRN2014/2015 2015/2016
Recruitment Rank Adjusted Recruitment Rank Recruitment Rank Adjusted
Recruitment Rank
East Midlands 259 9 59 10 144 9 32 9Eastern 542 3 146 2 229 4 61 4Greater Manchester 343 5 117 4 159 7 54 6Kent, Surrey and Sussex 66 13 15 15 43 12 10 14North East and North Cumbria 86 12 28 12 32 13 10 13North Thames 365 4 68 8 214 5 39 8North West Coast 644 1 175 1 299 2 81 2North West London 105 11 53 11 46 11 23 11South London 278 8 89 6 157 8 50 7South West Peninsula 43 15 19 14 17 15 8 15Thames Valley and South Midlands 56 14 24 13 27 14 12 12Wessex 337 6 124 3 288 3 106 1West Midlands 550 2 97 5 410 1 72 3West of England 192 10 81 7 133 10 55 5Yorkshire and Humber 334 7 62 9 171 6 31 10
Data adjusted to regional population, expressed as recruitment per 1M people
Lung Tumour Group SWP Recruitment
Data from Portfolio ODP – Cut off 06/12/15
Lung Tumour Group - Study Type
Data from Portfolio ODP – Cut off 06/12/15
33%
35%
65%
67%
Lung Tumour Group - Study Design
Data from Portfolio ODP – Cut off 06/12/15
37%
63%
100%
Acronym Study Type UKCRNID Trust Investigator Name End date Target Recruitment
(EDGE)Recruitment
(Portfolio)RTT
Rating
CANC - 3853 ARCTIC Commercial 17682 RCHT Talbot, Dr Toby 28-Sep-17 3 1 0 19
CANC - 4122 PACIFIC Commercial 18180 RCHT Talbot, Dr Toby 28-Oct-19 2 0 0 -1
Checkmate - 171 Commercial 18933 PHNT Yiannakis, Dr Dennis 15-Apr-21 15 0 0 -5
Genetics of EGFR Mutation Study (GEM): a Translational Study of the EORTC Lung Group (EORTC 08114)
Non-Commercial 16457 RCHT Talbot, Dr
Toby 01-Aug-17 120 12 14 -36
Lung ART Non-Commercial 5686 RD&E Ford, Dr Vicky 25-Oct-18 2 0 0 -39
Lung ART Non-Commercial 5686 T&S Walther, Dr
Julie 25-Oct-18 4 0 0 -37
LungCAST - Does smoking status after a diagnosis of lung cancer affect outcomes?
Non-Commercial 9851 T&S Pepperell, Dr
Justin 01-Mar-17 4 49 38 1161
NCRN - 2974 VESTA: Veliparib, carboplatin & paclitaxel in NSCLC Commercial 16393 NDHCT Napier, Dr
Mark 31-Mar-16 2 1 1 -20
STOMP Non-Commercial 10873 PHNT Yiannakis, Dr
Dennis 15-Nov-14 1 3 2 94
Lung Tumour Group – Open Studies from RAG Report
Data from CRN SWP RAG Report from EDGE – November 2015
NICE Pathway for Lung Treatment
Non-Commercial Study Opportunities
SPECIAL: Standard or PalliativE Care In Advanced Lung cancer Does early referral of patients with metastatic non-small cell lung cancer to UK specialist palliative care services make a difference in their quality of life or survival?(http://public.ukcrn.org.uk/search/StudyDetail.aspx?StudyID=18810)
OPTIMUM Trial - Randomised controlled trial comparing outpatient management of malignant pleural effusion via an indwelling pleural catheter and talc pleurodesis versus standard inpatient management in improving health related quality of life. (http://public.ukcrn.org.uk/Search/StudyDetail.aspx?StudyID=19615)
GEM (EORTC 08114) - Genetics of EGFR Mutation Study (GEM): a Translational Study of the EORTC Lung Group(http://public.ukcrn.org.uk/search/StudyDetail.aspx?StudyID=16457)
TAPPS - Evaluating the efficacy of thoracoscopy and talc poudrage versus pleurodesis using talc slurry: a randomised trial to determine the most effective method for the management of malignant pleural effusions in patients with a good performance status (http://public.ukcrn.org.uk/search/StudyDetail.aspx?StudyID=12537)
TARGET Trial - Randomised controlled trial to compare the diagnostic yield of Positron Emission Tomography Computerised Tomography (PET CT) targeted pleural biopsy versus CT guided pleural biopsy in suspected pleural malignancy(http://public.ukcrn.org.uk/search/StudyDetail.aspx?StudyID=19364)
The VIOLET study - VIdeo assisted thoracoscopic lobectomy versus conventional Open LobEcTomy for lung cancer, a multi-centre randomised controlled trial with an internal pilot (http://public.ukcrn.org.uk/search/StudyDetail.aspx?StudyID=18341)
CEDAR - A Phase II, randomised, open-label study of Gemcitabine/Carboplatin first-line chemotherapy in combination with or without the antisense oligonucleotide Apatorsen (OGX427) in advanced squamous cell lung cancers(http://public.ukcrn.org.uk/search/StudyDetail.aspx?StudyID=16622)
DIAPHRAGM - Diagnostic and Prognostic biomarkers in the Rational Assessment of Mesothelioma(http://public.ukcrn.org.uk/search/StudyDetail.aspx?StudyID=15376)
MARS2 - A study to determine if it is feasible to recruit into a randomised trial comparing (extended) pleurectomy decortication versus no pleurectomy decortication in the multimodality management of patients with malignant pleural mesothelioma (http://public.ukcrn.org.uk/search/StudyDetail.aspx?StudyID=15909)
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SWP Lung cancer Strategy?
• Prevention• Smoking cessation• Early diagnosis – CANDID• Smoking cessation at diagnosis• Treatment• QOL studies• Palliative care