magnesium in the murine artery: probing the products of corrosion (bowen et al., acta biomaterialia,...

8/13/2019 Magnesium in the murine artery: Probing the products of corrosion (Bowen et al., Acta Biomaterialia, 2013)

1/31

Pbos os tbj pjjr rjvojwj` vjrsoen eg tbj gehhewonm krtolhj9

V. C. Dewjn, I. @rjholb, kn` I. Meh`akn, Akmnjsoua on tbj auronj krtjry9 Vredonm tbj pre`ults eg lerresoen,Kltk Doeaktjr.(46;


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; OntreùltoenAkmnjsoua kn` ots khheys bkvj djjn bjkvohy rjsjkrlbj` on rjljnt yjkrs ùj te ontjrjst on tbjor kppholktoen

ks doekdserdkdhj vksluhkr slkggehònm S;Q. Vroer te wo`jsprjk` lhonolkh kèptoen, jxtjnsovj on votrekn` on vove

lerresoen tjstonm os rjquorj`. ]bohj tbjrj os k phjtberk eg lerresoen `ktk grea on votrejxpjroajnts S4Q, ot kppjkrs

tbkt on vovestu`y os k akier `jgolojnly eg tbj kdserdkdhj stjnt hotjrkturj. Aest lentrodutoens tbus gkr bkvj rjhoj`

en perlonj krtjrokh oaphknts S


3/31

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sudijlts, kn` rjhktovjhy bomb onstotutoenkh kn` akrmonkh lests eg beusonm. Ks kn khtjrnktovj, kn onjxpjnsovj on vove

ajtbe` eg doelerresoen soauhktoen usonm worjs S;


4/31

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Kùht akhj \prkmuj @kwhjy rkts wjrj knjstbjtozj` wotb oseghurknj on exymjn. Pbj ;6 aa worj sjmajnts

wjrj usj` te punlturj tbj krtjrokh k`vjntotok eg tbj kdèaonkh kertk, kn` tbj worj wks hj` on ger tbj guhh hjnmtb,

tbus gorahy jadj`ònm ot on tbj krtjrokh ajòk. 46 aa sjmajnts wjrj oaphkntj` prexoakhhy te tbj gorst worj,

wotbon tbj kdèaonkh kertk, kn`, kgtjr jxphkntktoen, wjrj usj` ger ajlbknolkh knkhysos tbkt os rjpertj` jhsjwbjrj

S;=Q. Ot os netj` tbkt tbj krtjrokh wkhh oaphkntktoen ajtbe` hklcs seaj gjkturjs eg k guhhy jxpkn`j` akmnjsoua

stjnt eg tbj skaj aktjrokh, onlhuònm9 (o) k hklc eg òrjlt dhee` lentklt ajknt te soauhktj k pest-jnlkpsuhktoen

jnvorenajnt, (oo) kn kdsjnlj eg helkh leh` werc tbkt weuh` aeògy tbj lerresoen conjtols, kn` (ooo) grjjèa grea

tbj lylhol strjssjs mjnjrkhhy jxpjrojnlj` dy stjnts. Pbos preljùrj wks rjvojwj` kn` kpprevj` dy Aolbomkn

Pjlbnehemolkh Znovjrsoty's Onstotutoenkh Knoakh Lkrj kn` Zsj Leaaottjj (OKLZL).

Tkts wjrj beusj` untoh tbjor jutbknozktoen on kller`knlj wotb tbj Vknjh en Jutbknksok eg tbj Kajrolkn

Wjtjronkry Ajòlkh Ksseloktoen kn` jxtrolktoen eg tbj worjs kt tjn toaj peonts rknmonm grea : te


5/31

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4.4.; Eptolkh oakmonm eg tbj surgkljEptolkh oakmonm eg tbj lerre`j` worj skaphjs wks pjrgeraj` wotb k ]oh` Bjjrdrumm A:k

stjrjeaolreslepj kn` k Hjolk JL< aolreslepj lkajrk (Hjolk Aolresystjas3 Duggkhe Mrevj, Ohhoneos) kt :6

neaonkh akmnogolktoen. ]botj-hombt ohhuaonktoen kn` jxpesurj sjttonms wjrj tbj skaj grea skaphj-te-skaphj te

preùlj leapkrkdhj oakmjs.

4.4.4 Aolreslepol Geurojr trknsgera ongrkrj` spjltreslepyGP-OT wks lenùltj` on òggusj rjghjltknlj ae`j wotb k Iksle GPOT-0466 spjltrepbeteajtjr jquoppj`

wotb kn OTP-


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djmkn kt k aonoaua ostknlj eg 6.: aa grea tbj jn` eg tbj worj. Lress sjltoens wjrj prjpkrj` dy mron`onm tbj

jxpesj` worj on k ajtkhhemrkpbol gksboen wotb 766- kn` 266-mrot \oL pkpjr kn` pehosbonm wotb k ; a Kh4E


7/31

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Leapkrosen eg tbj etbjr skaphj surgkljs peontj` te lhjkr oggjrjnljs. Pbjrj wjrj ne strenm onòlktoens eg

pottonm er helkhozj` kttklc tbkt rjùlj` tbj kppkrjnt òkajtjr eg oaphknts rjaevj` djgerj 4? kys. K tbon,

trknshuljnt, wbotj surgklj hkyjr wks jvo`jnt en tbj worj oaphkntj` ger ;4 `kys, kn` wks aerpbehemolkhhy òggjrjnt

grea tbj helkhozj` `jpesots prjvoeushy edsjrvj`. K soaohkr trknshuljnt wbotj hkyjr kppjkrj` te levjr njkrhy tbj

jntorj ;0 `ky skaphj ks wjhh ks worjs grea sudsjqujnt toaj peonts. En tbj 4? kn`


8/31

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4pjkc kt 2=< la-;. Vjkc ae`jhonm wks usj` te jxtrklt tbj ontjnsotojs eg tbjsj twe pjkcs djtwjjn ;0 kn` 4? `kys

on vove(Gomurj 0). Ot wks edsjrvj` tbkt pjkc ontjnsotojs rjakonj` rjhktovjhy lenstknt ger K-typj sudstotutoen, kn`

vkroj` dy enhy ;6%. Ontjnsotojs lerrjspenònm te D-typj sudstotutoen, bewjvjr, `jlhonj` dy njkrhy kn er`jr eg

akmnotu`j evjr tbj skaj toaj pjroe`.

\pjltrua sudtrkltoen wks utohozj` te osehktj kn OT spjltrua ger tbj gorst-te-gera surgklj preùlt. K sakhh

oshkn` eg tbj sjlen`-te-gera preùlt wks vosodhj kt = `kys3 ot wks knkhyzj` kn` tbj klquorj` spjltrua wks

sudtrkltj` grea tbj mjnjrkh slkn (Gomurj


9/31

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Jhjajntkh akpponm eg tbj skaj sjrojs eg lress sjltoens rjvjkhj` tbj òstrodutoen eg tbj cjy jhjajnts

akmnjsoua, exymjn, pbespberus, kn` lkhloua on tbj sjltoens eg ontjrjst. Pbjsj akps kn` lerrjspenònm rjmoenkh

DJOs krj prjsjntj` on Gomurj =. Pbj jhjajntkh somnkturjs rjlengora tbj twe òstonlt lerresoen preùlts tbkt wjrj

kppkrjnt on tbj sjrojs eg DJOs (Gomurj 7). Kt = `kys, k lkhloua- kn` pbespberus-lentkononm unogera surgklj hkyjr

os edsjrvj` on k`òtoen te kn onnjr hkyjr leaprosonm akmnjsouakhdjot aulb hjss tbkn tbj unkùhtjrktj` ajtkh

kn` exymjn. Vbespberus wks onlerperktj` te k hoaotj` jmrjj on pertoens eg tbj onnjr hkyjr, dut wks aerj bombhy

lenljntrktj` on tbj eutjr (surgklj) hkyjr. Lkhloua wks bombhy lenljntrktj` on tbj surgklj hkyjr, dut wks net

onlerperktj` onte tbj onnjr hkyjr te tbj jxtjnt pbespberus wks. \eaj vkroktoens on tbolcnjss eg tbj eutjr hkyjr krj

edsjrvj` kt = `kys, lensostjnt wotb tbj lerrjspenònm DJO. Kt ;0 `kys, tbj J@\ akps wjrj qukhotktovjhy soaohkr.

Pbj lerresoen hkyjr bk` tbolcjnj` k dot kn` tbj preùlts bk` djleaj seajwbkt aerj sjmrjmktj`, wotb k aerj

òstonlt Am- kn` E-djkronm hkyjr njkr tbj worj ljntjr. Vbespberus, kmkon, wks prjsjnt kt k mrjktjr `jptb tbkn tbj

lkhloua, wbolb wks lengonj` te k unogera hkyjr kt tbj surgklj. Akmnjsoua sjjas te bkvj djjn osphklj` khaest

leaphjtjhy dy lkhloua njkr tbj surgklj, aknogjstonm ks k hew x-rky somnkh grea tbj eutjr rjmoen.

Hktjr toaj peonts bk` jhjajntkh òstrodutoens tbkt `jvoktj` grea tbj leapklt, twe-rjmoen strulturj kt tbj =

kn` ;0 `ky toaj peonts. Pbj proakry òggjrjnlj wks k hess eg ontjmroty eg tbj onnjr lerresoen hkyjr, jvo`jnlj` dy

rjmoenkh hess eg somnkh grea akmnjsoua kn` exymjn kn` tbjor rjphkljajnt wotb lkrden kn` lbheronj somnkhs

lbkrkltjrostol eg jpexy (lkrden kn` lbheronj net sbewn on Gomurj =). Vbespberus onlerperktoen onte tbj onnjr

lerresoen hkyjr wks aerj preneunlj` on seaj helktoens, kn` wks klleapknoj` dy lkhloua aerj se tbkn kt jkrhojr

toajs. Prklj jhjajnt akps eg seòua, lbheronj, kn` lkrden wjrj khse preùlj`, dut wjrj eg hoaotj` utohoty.

Bjkvohy drombtnjss- kn` lentrkst-jnbknlj` jxkaphjs eg tbjsj akps grea tbj ;0 `ky toaj peont krj onlhu`j` on

Gomurj 2. Pbj lkrden (Gomurj 2 K) somnkh wks preùlj` proakrohy grea tbj surreunònm jpexy er grea helktoens

wbjrj tbj jpexy bk` pjnjtrktj` onte tbj skaphj.


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0 @oslussoen0.; Oapholktoens eg sur gklj oakmonm

Ljhhs kttklbj` te tbj akmnjsoua surgklj krj tbeumbt te dj rjspensodhj ger tbj unjxpjltj` leherktoen

edsjrvj` on tbj : `ky skaphj (Gomurj ;). Hktjr skaphjs `o` net sbew jvo`jnlj eg doehemolkh aktjrokhs en tbj

surgklj. Pbj hklc eg kppkrjnt vksluhkr ljhh kttklbajnt er aktrox syntbjsos kt tbj Am-krtjry ontjrgklj edsjrvj`

`uronm surgklj knkhysos os k tjstkajnt te akmnjsouas jxljhhjnt doeleapktodohoty. Ot khse summjsts tbkt akmnjsoua

pjr sjaky net stoauhktj ontoakh bypjrphksok eg saeetb auslhj ljhhs, wbolb os tbj bkhhakrc ae`j eg gkohurj ger

stjntj` krtjrojs S4?Q. Bewjvjr, oniury grea knmoephksty kn` tbj phkljajnt eg k akmnjsoua stjnt bks djjn

edsjrvj` jxpjroajntkhhy S


11/31

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dy lkrdenktj rjakons lensostjnt, dut khtjrnktovj sudstotutoen ger VE0


12/31

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jhjltrehytjs. Kn onlrjksj` pB kt tbj surgklj, typolkh ger Am doeaktjrokhs S


13/31

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Pbj eutjr preùlt èjs kppjkr te bkvj k wjkc lkrden somnkturj, wbolb aky dj k leadonktoen eg

onlerperktj` lkrden (grea lkrdenktj, `jtjraonj` dy GP-OT) kn` jpexy tbkt ellupoj` surgklj `jgjlts. K lkrden

somnkh wks net mjnjrktj` grea tbj onnjr lerresoen hkyjr, summjstonm tbkt tbos hkyjr ò` net lentkon somnogolknt

qukntotojs eg lkrdenktj. Lbheronj (Gomurj 2 D) os k lenstotujnt eg tbj jpexy, kn` se os kmkon prjsjnt surreunònm

tbj worj sjltoen on hew lenljntrktoens. K Lh somnkh wks edsjrvj` kt seaj j`mj sotjs kgtjr tbj akp lentrkst wks

jnbknlj`. Pbj ae`j eg Lh onlerperktoen on tbj lerresoen hkyjr os net jvo`jnt grea tbjsj `ktk (j.m. AmLh4

pkrtoluhktj er k`serdj ontjrgklokh lbhero j oens), dut ot aky dj soaohkr te tbj on votreonlerperktoen eg lbhero`j

oens edsjrvj` dy ]ohhuajot jt kh.S06Q. \uggolj` te sky, Lh os k trklj lenstotujnt te wbolb tbj duhc knkhysos

ajtbe`s usj` bjrj krj net sjnsotovj, kn` weuh` rjquorj òggjrjnt ajtbe`s eg jvkhuktoen te `jslrodj leaphjtjhy.

\eòua (Gomurj 2 L) èjs net kppjkr te dj prjsjnt on kny `jtjltkdhj qukntoty, kn` tbj wjkc somnkh prjsjntj` on

tbos rjpert eromonktjs grea tbj tkohs eg tbj akmnjsoua Cpjkc. Pbus, seòua èjs net kppjkr te dj rjtkonj`

ùronm tbj geraktoen eg pbysoehemolkh lerresoen preùlts en akmnjsoua.

K leapesotoenkh stu`y eg tbj onnjr, Am-E lerresoen hkyjr wks kttjaptj` usonm sonmhj-peont jnjrmy

òspjrsovj spjltreslepy. Bewjvjr, tbj sakhh wo`tb eg tbos lerresoen hkyjr kt jkrhy toajs rjsuhtj` on jhjltren

ontjrkltoen wotb tbj eutjr lerresoen hkyjr kn`/er tbj akmnjsoua lerj. Hocjwosj, hktjr ongohtrktoen eg jpexy onte tbj

lerresoen hkyjr prjvjntj` kllurktj jnjrmy òspjrsovj spjltreslepy rjsuhts grea djonm edtkonj`. Guturj werc aky

utohozj hkrmjr-mjeajtry spjloajns er tbesj tbkt gklohotktj tbj mrewtb eg k tbolc lkhloua-pbespbktj evjrhkyjr te

mrew k suotkdhy hkrmj, stkdhj exymjn-lentkononm hkyjr. Lkrjguh x-rky aolreknkhysos en sulb k preùlt aky rjvjkh

og tbj Am9E rktoe os lhesjr te AmE (;9;), Am(EB)4(;94), AmLE


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0.0 Vrepesj` henm-tjra lerresoen ajlbkno saLerresoen ajlbknosas ger doekdserdkdhj aktjrokhs bkvj mjnjrkhhy djjn gerauhktj` dksj` en on votre

jxpjrojnljs S06-04Q, kn` typolkhhy `jkh enhy wotb jkrhy-stkmj lerresoen djbkvoer kn` surgklj aeògolktoen.

Kttjntoen bks net djjn pko` te akss trknspert pbjneajnk on tbj qukso-stjk`y stktj, ner bks tbj ossuj eg tjraonkh

drjkcèwn eg akmnjsoua doeaktjrokhs djjn suggolojnthy òslussj`. Zsonm tbj ktk prjsjntj` on tbos lentrodutoen,

kspjlts eg tbj lerresoen ajlbknosa on tbj qukso-stjk`y stktj kn` tjraonkh stkmjs aky dj jhulo`ktj`. Vbjneajnk

eg ontjrjst krj `jpoltj` on Gomurj ;6, kn` onlhu`j akss trknspert on tbj lerresoen hkyjr kn` tbj oen jxlbknmj

ajlbknosa hjk onm te BKp aeògolktoen (Gomurj ;6 K), kn` jstkdohozktoen eg tbj onnjr lerresoen hkyjr on tbj

tjraonkh stkmjs eg lerresoen (Gomurj ;6 D). Wjrtolkh slkhjs kt tbj surgklj on tbj Gomurj ;6 krj jxkmmjrktj` ger

lhkroty.

On tbj jstkdhosbj` lerresoen hkyjr kt =4; `kys, tbolcjnonm eg tbj onnjr lerresoen hkyjr os edsjrvj` te

premrjss shewhy rjhktovj te tbkt wbolb ellurrj` ùronm tbj gorst wjjc eg rjso`jnlj. Pbos toaj pjroe` leaprosjs k

qukso-stjk`y stktj. Pbj rjksen ger tbj `jlrjksj on lerresoen rktj bks aulb te è wotb tbj onotokh `jvjhepajnt eg kn

kpktotol evjrhkyjr S


15/31

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`jtjraonj` kt tbos toaj djlkusj tbj ae`j eg pbespberus onlerperktoen (o.j. ks pbespbktj, pbespbktj òdksol,

pbespbktj aenedksol, jtl.) os un`jtjraonj .

Oen jxlbknmj djtwjjn tbj Am/Lk BKp kn` tbj surreunònm jnvorenajnt os suspjltj` te ellur

lenlurrjnthy wotb tbj akss trknspert pbjneajnen. Pbj slbjaktol rjprjsjntktoen eg tbj oen jxlbknmj preljss

(Gomurj ;6 K) ohhustrktjs tbj òssehutoen eg tbj Am/Lk BKp kn` prjlopotktoen eg tbj K-typj BKp en tbj surgklj. K

`jtkohj` òslussoen eg tbos ajlbknosa wks prjvoeushy prjsjntj` kn` os tbjrjgerj net rjotjrktj` bjrj. Pbj

prjlopotktj K-typj BKp geras k ostonlt surgklj hkyjr, ks sbewn on Gomurj = kn` ohhustrktj` on Gomurj ;6 D.

Jvjntukhhy, tbj lensuaptoen eg Am/Lk BKp os jxpjltj` te tbon tbj kpktotol evjrhkyjr suggolojnthy te jxpesj tbj

onnjr lerresoen hkyjr te tbj krtjrokh jnvorenajnt. ]ercs en lenvjntoenkh akmnjsoua lerresoen rjgjrjnlj tbj

`jstkdohozktoen eg Am(EB)4/AmE pkrtokhhy pretjltovj gohas dy lbhero`j S0


16/31

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hkyjr eg lerresoen, wbohj tbjrj wks k sakhh kaeunt eg lkrden edsjrvj` on tbj skaj hkyjr. K hess eg ontjmroty eg tbj

kpktotol eutjr lektonm kppjkrj` te rjsuht on helkh mrewtb eg tbj onnjr Am- kn` E-lentkononm lerresoen hkyjr.

Ajlbknosas rjhktj` te oen jxlbknmj, akss trknspert on tbj qukso-stjk`y stktj (~= te 4; `kys), kn` tbj ae`j eg

tjraonkh drjkcèwn on tbj akmnjsoua oaphknts kgtjr ~4; `kys krj summjstj` dksj` en jxpjroajntkh edsjrvktoens.

7 Klcnewhj`mjajntsVCD wks suppertj` dy gjhhewsbop gun`s grea tbj @jWhojm Geun`ktoen kn` sudsjqujnthy dy tbj Kajrolkn

Bjkrt Ksseloktoen ùronm tbos werc. Ewjn Aohhs kn` Gjholok Nop eg tbj Kpphoj` Lbjaolkh kn` Aerpbehemolkh

Knkhysos Hkderktery krj klcnewhj`mj` ger tbjor bjhp on prjpkronm skaphjs ger jhjltren aolreslepy. Deyo Bke

kn` Vreg. _ecj Cbon _kp grea tbj Vbysols @jpkrtajnt kt Aolbomkn Pjlbnehemolkh Znovjrsoty krj mrktjguhhy

klcnewhj`mj` ger usj eg kn` kssostknlj wotb tbj GP-OT aolreslepj. Pbkncs khse te K`ka @rjholb ger bos

kssostknlj prjpkronm worj lress sjltoens kn` te Jaohy \bjkrojr wotb bjr kssostknlj on jòtonm tbj aknuslropt.

= TjgjrjnljsS;Q Akno M, Gjhàkn A@, Vktjh @, Kmrkwkh LA. Lerenkry stjnts9 k aktjrokhs pjrspjltovj. Doeaktjrokhs

466=3429;72?-=;6.

S4Q Corchkn` NP, Dordohos N, \tkomjr AV. Kssjssonm tbj lerresoen eg doe`jmrk`kdhj akmnjsoua oaphknts9 k lrotolkh

rjvojw eg lurrjnt ajtbeèhemojs kn` tbjor hoaotktoens. Kltk Doeaktjr 46;4329?4:-


17/31

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S:Q \hettew PH, Vkckhk T, Eckdj P, Bjhhonmk @, Hevjl TI, Poe GE, jt kh. Eptolkh lebjrjnlj teaemrkpby kn`

ontrkvksluhkr uhtrkseun` oakmonm eg doekdserdkdhj akmnjsoua stjnt `jmrk`ktoen on perlonj lerenkry krtjrojs.

Lkròevksl Tjvksl Aj` 46623?9402-:0.

S7Q ]ottlbew J, K``jn N, Tojàuhhjr I, \kvkr` L, ]kcsakn T, Drkunj A. Doerjserdkdhj `rum-jhutonm

akmnjsoua-khhey slkggeh`9 jsomn kn` gjksodohoty on k perlonj lerenkry ae`jh. JureOntjrvjntoen 9 ieurnkh eg

JureVLT on lehhkderktoen wotb tbj ]erconm Mreup en Ontjrvjntoenkh Lkròehemy eg tbj Jurepjkn \elojty eg

Lkròehemy 46;


18/31

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S;0Q Dewjn VC, @rjholb I, Meh`akn I. Yonl jxbodots o`jkh pbysoehemolkh lerresoen djbkvoer ger doekdserdkdhj

stjnts. K`v Aktjr 46;


19/31

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S47Q Grest TH, Akrtjns ], ]ohhokas VK, Chepremmj IP. Tkakn kn` ongrkrj` spjltreslepol stu`y eg tbj vovoknotj-

mreup pbespbktjs vovoknotj, dkrolotj kn` dedojrrotj. Aonjrkh Akm 46643779;67


20/31

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S


21/31

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Pkdhj ;Ongrkrj` dkn`s edsjrvj` on tbj mjnjrkh GPOT spjltrk (Gomurj


22/31

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Gomurj ;K premrjssoen on tbj eptolkh lbkrkltjr eg tbj lerresoen hkyjr os edsjrvj` on tbj oaphknts wotb

onlrjksonm oaphkntktoen toaj. Khh oakmjs wjrj lkpturj` kt :6neaonkh akmnogolktoen3 tbj slkhj dkr kt hewjr

rombt kpphojs te khh stjrjeaolremrkpbs.


23/31

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Gomurj 4\jlen`kry jhjltren oakmj sbewonm tbj k`bjsoen eg rj` dhee` ljhhs te tbj akmnjsoua worj

surgklj kgtjr govj `kys on vove.


24/31


25/31

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Gomurj 0Vjkc ae`jhonmkn jxkaphj eg wbolb os sbewn ger tbj 4? `ky toaj peont (K)yojh`j` pjkc

ontjnsotojs ger lbkrkltjrostol eg K-typj lkrdenktj sudstotutoen (226 la-;) kn` D-typj sudstotutoen (2=< la-;) tbkt

krj `jpoltj` wotb k seho` honj kn` drecjn honj, rjspjltovjhy (D). K rktoe eg tbj gerajr te tbj hkttjr os lensostjnthy

mrjktjr tbkn unoty, on`olktonm K-typj lkrdenktj sudstotutoen on tbj surgklj pre`ult (L).


26/31

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Gomurj :Leapkrosen eg tbj spjltrk grea tbj gorst-te-gera pre`ult (Am/Lk BKp) kn` sjlen`-te-gera,

wbotj leherj` pre`ult (K-typj BKp) kt = `kys. Pbj Am/Lk BKp wks mjnjrktj` dy sudtrkltoen eg tbj K-typj BKp

spjltrua grea kn evjrkhh surgklj spjltrua (Gomurj


27/31

- 4= -

Gomurj 7Tjprjsjntktovj dklcslkttjrj` jhjltren oakmjs (


28/31

- 42 -

Gomurj =Dklcslkttjr jhjltren oakmjs kn` jhjajntkh (J@\) akps ger =, ;0, 4;, kn`


29/31

- 4? -

Gomurj 2Jxkaphj eg tbj trklj jhjajnt akps ger lkrden (K), lbheronj (D), kn` se`oua (L) grea tbj ;0

`ky akmnjsoua worj sjltoen.


30/31

-


31/31

Gomurj ;6\lbjaktol sbewonm trknsgeraktoens suppesj` te dj tkconm phklj on tbj qukso-stjk`y stktj (K),

onlhuònm kpktotol oen jxlbknmj kn` rjkltoens kt tbj Am-Am/E ontjrgklj, kn` ùronm tbj tjraonkh drjkcèwn stkmj

(D), eaonktj` dy ossehutoen eg tbj Am/E hkyjr upen jxpesurj te tbj krtjrokh jnvorenajnt.

magnesium in the murine artery: probing the products of corrosion (bowen et al., acta biomaterialia,...

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