Making sense of your Data

Your partner for biological data analysis, mining and interpretation

www.altrabio.com

Speed-up your R&D projects

AltraBio is a biotechnology company providing Research and Development (R&D) services in analysis and interpretation of biomedical data in both preclinical and clinical development.

Particularly focused on OMICS (e.g., genomics, transcriptomics, proteomics) and Flow/Mass cytometry technologies, the goal of AltraBio is to unlock the value captured in large scale datasets generated in life science experimental studies.

AltraBio's team has extensive experience in statistical modelling, data mining and software/database design, as well as educational and professional background in biomedical sciences and medicine. In addition to designing and implementing computational solutions, they have the knowledge and skills to interpret the results of quantitative analyses in the context of current biomedical knowledge.

We can work together through subcontracts or collaborative research projects. AltraBio has already successfully applied its expertise at the service of both industrial and academic partners from various segments of life science.

AltraBio Services for Research & Clinical Trials

OMICS DATA ANALYSIS AltraBio provides the complete range of preprocessing and statistical analysis services relevant to all current microarray and sequencing technologies (e.g., differentially expressed genes, SNP associations).

• Study design• Preprocessing & Quality control• Flexible statistical analyses• Gene & Geneset Approaches• Biological interpretation

• Data hosting and continuous access to our in-house visualisation and exploration tools (WikiBioPath)

• Comprehensive report of Analysis results & Biological findings

MASS/FLOW CYTOMETRY DATA ANALYSIS AltraBio offers comprehensive services for cytometry data analysis. To maximise the value of your experimental results and to speed up the process, AltraBio’s offer covers the entire data analysis workflow.

• Quality control and preprocessing• Automated gating & Population

characterisation• Advanced Visualisation

• Cross-sample analysis for predictive modelling & correlations identification

• Use of Machine Learning state-of-the-art tools & methods

For Exploration

For Clinical Trials• Manual Gating Automation• Adaptable to your gating strategy• Detection of inconsistencies in

manual gating

• Increase in reliability & avoidance of manual gating subjectivity/variability

• Use of the latest Machine Learning methods

Which applications?

What you need!

Drug Repositioning

Biomarker Discovery

Pathway Analysis

Patient Stratification

Automated Population Identification

Toxicity Studies

Pathogen Identification

High-Throughput Screening

MMP-7 is a predictive biomarker of disease progression in patients with idiopathic pulmonary fibrosis. Bauer Y, White ES, de Bernard S, … ERJ Open Res. 2017 Mar; 3(1).

Mature IgM-expressing plasma cells sense antigen and develop competence for cytokine production upon antigenic challenge. Blanc P, Moro-Sibilot L, Barthly L, … Nat Commun. 2016 Dec; 7:13600.

Immune signatures of protective spleen memory CD8 T cells. Brinza L, Djebali S, Tomkowiak M,… Sci Rep. 2016 Nov; 6:37651.

CD1d-restricted peripheral T cell lymphoma in mice and humans. Bachy E, Urb M, Chandra S,… J Exp Med. 2016 May; 213(5):841-57.

Terminal NK cell maturation is controlled by concerted actions of T-bet and Zeb2 and is essential for melanoma rejection. van Helden MJ, Goossens S, Daussy C,… J Exp Med. 2015 Oct; 212(12):2015-25.

Subcontracts Hundreds of analyses performed with major pharmaceutical, biotechnology

& cosmetics companies

Collaborative projects PREDIVAC Consortium - ANR

INSERM/CIRI Lyon, UCBL, The Cosmo company

• R&D personnel with multidisciplinary background

• Biological interpretation• Customised statistical analysis & data

visualisation• Bioinformatics tools design and

implementation

• Access to our visualisation & exploration tools

• Support at each step of your project• Publication quality graphs• Comprehensive reports• Time & cost effective services

How can we work together?

Recent publications…

Why AltraBio?

Contact us

www.altrabio.com

30 Rue Pré-Gaudry69007 LYON, FRANCE

Phone: +33 (0)4 26 84 69 63Fax: +33 (0)9 57 49 03 01

ContactUs@altrabio.com