malignant neoplasia... 2nd lab

21
Neoplasia 4…. By shin n Kavita Pics frm David Santos

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Page 1: malignant neoplasia... 2nd lab

Neoplasia 4….By shin n KavitaPics frm David Santos

Page 2: malignant neoplasia... 2nd lab

AMYLOID DEPOSITS DISEASE : AMYLOID , THYROID

Page 3: malignant neoplasia... 2nd lab

Disease : Basal cell CACharacteristic appearance : Picket fence appearance

Cells at pointer : Palisade of Basal cells

Page 4: malignant neoplasia... 2nd lab
Page 5: malignant neoplasia... 2nd lab
Page 6: malignant neoplasia... 2nd lab

Disease : Squamous cell CA

Epidermis that invaded the dermis.. Squamous cells arranged into lobules

Keratinization in the centers .. Known as keratin pearls

Page 7: malignant neoplasia... 2nd lab

Disease : tumor emboli, lung

Shows hematogenous spread.. The malignant cells will be found w/I the BV.

Landmark : normal alveoli

Blood vessel

Malignant cells occluding the BV

Page 8: malignant neoplasia... 2nd lab

Hematogenous spread in Liver - Gross

Page 9: malignant neoplasia... 2nd lab

Hair follicle

Sebaceous gland

Dermoid cyst , ovary

There’s ectodermal differentiation due to presence of totipotential cell thus presenting with sebaceous gland, hair follicles, etc.See stuff that are not suppose to be seen in ovary!

Page 10: malignant neoplasia... 2nd lab

Hair, teeth and sebaceous fluid seen in ovary

Page 11: malignant neoplasia... 2nd lab

Normal thyroid follicle

The thyroid follicles are surrounded by malignant cells … they are arranged into papillary pattern.

Psammoma’s body

Papillary CA, thyroid Lymphoid spread

Page 12: malignant neoplasia... 2nd lab

Papillary CA, thyroid Lymphoid spread

Orphan Annie nuclei appearance under HPO

Page 13: malignant neoplasia... 2nd lab

Thyroid follicle

Infiltration of Leukocytes

Appears like Lymph nodeBut actually , it’s a thyroid gland with autoimmune disease known as Hashimoto’s thyroiditis

Page 14: malignant neoplasia... 2nd lab

Thyroid hyperplasia

Grave’s Disease

Page 15: malignant neoplasia... 2nd lab

Ducts invading the stroma so there is reduced amount of stroma..This is due to abnormality of ductal lining cell..

Invasive Ductal carcinoma

Page 16: malignant neoplasia... 2nd lab

Pleomorphism of cell and nucleus

Hyperchromatic nucleus

Elongated duct

Rectal Adenocarcinoma

Page 17: malignant neoplasia... 2nd lab
Page 18: malignant neoplasia... 2nd lab

Chorionic villi with hydropic degeneration

Hydatidiform mole (partial mole)

Page 19: malignant neoplasia... 2nd lab

Hydatidiform mole – Gross…Appears like fish egg… WTF??? Does it???

Page 20: malignant neoplasia... 2nd lab
Page 21: malignant neoplasia... 2nd lab

Good Luck!!!!!

Thnk u!!!!!!!!!!!!