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Elixir Marketing Plan - 2008 – 2009 1 / 91 Marketing Plan Prepared for: Prof. Jean François David Prepared by: Livia Frincu Diana Mihai Alexandre Aymard Pauline Dreyer Xing Liu Salman Barrada Noé Nagata Maylïs Bontemps - 14 th of October 2008 -

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Page 1: Marketing Plan - davidjf.free.frdavidjf.free.fr/MkingPlan/Elixir Marketing Plan.pdf · Elixir – Marketing Plan - 2008 – 2009 1 / 91 Marketing Plan Prepared for: Prof. Jean François

Elixir – Marketing Plan - 2008 – 2009 1 / 91

Marketing Plan

Prepared for: Prof. Jean François David

Prepared by:

Livia Frincu Diana Mihai

Alexandre Aymard Pauline Dreyer

Xing Liu Salman Barrada

Noé Nagata Maylïs Bontemps

- 14th of October 2008 -

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Table of Content

Statement of Confidentiality and Non-Disclosure ..................................................................... 4 Abstract ...................................................................................................................................... 5 Our Story…................................................................................................................................ 6 Company Presentation................................................................................................................ 8

A. Elixir Ltd ........................................................................................................................ 8 B. Organization ................................................................................................................... 8 C. Slogan............................................................................................................................. 9

Objectives................................................................................................................................. 10 Start-up Analysis ...................................................................................................................... 11 Methodology ............................................................................................................................ 13

A. Market Study ................................................................................................................ 13 B. Process.......................................................................................................................... 13

1. Representation.......................................................................................................... 13 2. Product Breakdown Structure .................................................................................. 14 3. Responsibility Assignment Matrix........................................................................... 14 4. Team Contacts.......................................................................................................... 15

C. Planning........................................................................................................................ 15 1. Work Breakdown Structure...................................................................................... 16 2. Gantt chart ................................................................................................................ 17

Market study............................................................................................................................. 18 A. SWOT........................................................................................................................... 18 B. PEST............................................................................................................................. 22 C. Open Market................................................................................................................. 24

Strategy..................................................................................................................................... 31 A. Forces analysis – Porter’s Network Model: ................................................................. 31 B. Ansoff Matrix Analysis ................................................................................................ 32 C. Segmentation................................................................................................................ 34 D. Maslow’s hierarchy of needs........................................................................................ 35 E. Blue Ocean ................................................................................................................... 36

Marketing Mix.......................................................................................................................... 38 A. DNA analysis ............................................................................................................... 38 B. Products........................................................................................................................ 39

1. Art of Living Pack.................................................................................................... 39 2. Alzheimer Pack ........................................................................................................ 43 3. Cancer Pack.............................................................................................................. 46 4. Youth Pack ............................................................................................................... 50 5. Bracelet/Watch ......................................................................................................... 52

C. Promotion ..................................................................................................................... 56 1. Through posters, brochures and movie .................................................................... 56 2. Through people ........................................................................................................ 56 3. Website..................................................................................................................... 57

D. Place ............................................................................................................................. 58 E. Process.......................................................................................................................... 63 F. Risks Assessment ......................................................................................................... 66

1. Ethics........................................................................................................................ 66 2. Financial risks .......................................................................................................... 67 3. Technological risks .................................................................................................. 67

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G. Future ........................................................................................................................... 68 1. Expanding Elixir’s business ..................................................................................... 68 2. Future Technologies................................................................................................. 69

Finance ..................................................................................................................................... 70 A. Costs ............................................................................................................................. 70

1. Fixed Costs............................................................................................................... 70 2. Variable Costs .......................................................................................................... 72

B. Scenarios ...................................................................................................................... 72 Appendix .................................................................................................................................. 74 References ................................................................................................................................ 91

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Statement of Confidentiality and Non-Disclosure This document contains proprietary and confidential information. All data submitted to Mr. Jean François David is provided in reliance upon its consent not to use or disclose any information contained herein except in the context of his business dealing with Elixir Ltd. The recipient of this document agrees to inform its present and future employees and partners who view or have access to the document’s content of its confidential nature. The recipient agrees to instruct each employee that they must not disclose any information concerning this document to others except to the extent that such matters are generally known to, and are available for use by the public. The recipient also agrees not duplicate or distribute or permit others to duplicate or distribute any material contained herein without Elixir Ltd’s express written consent. Elixir Ltd. retains all title, ownership and intellectual property rights to the material and trademarks contained herein, including all supporting documentation, files, marketing material, and multimedia. BY ACCEPTANCE OF THIS DOCUMENT, THE RECEPIENT AGREES TO BE BOUND BY THE AFOREMENTIONED STATEMENT.

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Abstract

As Shakespeare once said through its famous character, Hamlet, « we know what we are but

know not what we may be ». This was the start up idea that gave birth to the concept of Elixir

Health Care Center. We all remark these days that the process of classical disease care has

failed us and that the appropriate answer is more and more turned into individual preventive

health care. Given information now available, people can become proactive in managing their

own health and remain well longer.

As a consequence, we, a group of specialists in different medical fields and management

decided to launch a new concept in health care: preventive medicine genetic-based. Although

the ideas which compose this concept are well known separately, the combination of the two is

quite a new trend for the society. A very few actors on the market dared to combine the

genetics with the traditional treatments. What Elixir intends to do is to bring together the

expertise of the DNA specialists, the old (i.e. Chinese, Indian) and the new preventive

medicine (nutrigenomics). Its main gold is to educate the people and to change their idea about

their DNA heritage.

Our services will be, in a first phase, addressed to high income population (i.e. executives). It

will consist in a genetic mapping analysis followed by a series of personalized packages

ranging from simple lifestyle recommendations to biomedication, Chinese and Indian

preventive medicine, psychological support and so on.

Another innovative aspect of our project consists in the usage of the RFID technology in the

follow up process of our patients. Thanks to our partnership with Hewlett Packard we will be

one of the first healthcare centers which will be able to track its patients’ record through this

modern technology.

It may seem like God’s work our attempt to change people’s destiny, but it is not. We are just

following the normal path of the medical R&D advancements and the new trends in preventive

medicine in order to respond to people’s concern about living a long healthy life. As professor

Gerald Gitsch from Freiburg University Medical Centre (Switzerland) said “If you know about

your health, you can change your healthcare behaviour, and then doctors can prescribe

medication, which can prevent you from getting these diseases.”

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Our Story…∗∗∗∗

Once upon a time….

Elixir is the story of a brilliant team willing to change the world while making money. It is the

story of doctors sick and tired of curing people instead of preventing them form being ill.

Everything began with a discovery: the influence of our genes on our future diseases. This

was known for a long time, but Maylis Bontemps is the one that discovered the place on the

genes that influenced on that. She is a brilliant doctor, specialist of Alzheimer, and she did not

want to see dying people anymore. So she decided to open a prevention center that would

allow her to prevent people from being sick, and that would make a millionaire of her. She

will be the president of the center and in charge of the Alzheimer Package.

She contacted some of her good friends from Harvard to offer them to take part into her

project. She only hired the best.

First of all she contacted her best friend Livia Frincu. Livia came from Romania and made all

her studies with Maylis. She is able to work 20 hours a day. She won several prizes, such as

discovery of the year 2000, or best doctor of the universe 2003, 2004 and 2005. Her father

was alcoholic and her mother was obese, so she saw a lot of people having bad life styles

around her and is very interested in the subject. Her final thesis was on the “art of living”. She

will therefore be in charge of the Art of Living Package.

Then she called Salman Barrada. Salman used to be a guru in a sect when he was young. He

was arrested by the police, and feared losing his wife and son. He then came back in the right

way and became a very famous researcher around the subject of “remaining young”. He

believes in eternal life. He will be happy to take care of the Youth Package.

Alexandre Aymard was her third phone call. He was a psychologist for 8 years, but get tired

of listening to people always complaining about their life. So he decided to cure patients that

had cancer. Unfortunately for him, and even tough he was a very good doctor, he could not ∗ Please consider this part as a parody of the start-up of our project.

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cure everyone. He saw one of his patients dying, and then made a depression. Another

psychologist cured him, and now he decided to prevent rather than to cure. He was therefore a

very interesting partner for Maylis. He would take care of developing the Cancer Package and

would also be a psychologist when needed.

Alexandre then offered Maylis to call the famous psychologist that helped him when he was

depressed. Her name was Diana Mihaï. She was also from Harvard, but never met the other

members of the team as she did not follow the same courses. Anyway she was well known for

her competencies and for having helped very famous people such as Paris Hilton.

As Diana is really fond of Alexandre, she was delighted to accept the psychologist job.

Xing Liu knew nearly all the team as she studied all the specialties: she is exceptionally

gifted. As she was getting bored at Harvard, she travel the world, discovering nearly all the

medicines: Chinese, Indian, Korean, Acupuncture....When Maylis called her she was in the

jungle, but was happy to come back to the city’s comfort. So she agreed to be a doctor, as

long as she could practice varied medicines.

Pauline Dreyer was the last person Maylis called. Her father wanted a boy so that he could

become a doctor like him. He was disappointed to have a daughter, and raised her as if she

was her son. He forced her to become a doctor, but she never wanted to cure people. In order

to disobey her father, she decided to accept the position as a doctor and to prevent rather than

cure the diseases. Nevertheless, she is good at what she does, and is always happy to help the

others.

The team also needed another member that would not be a doctor, to build the partnerships

with the local partners. Pauline new the right person: Noé Nagata. Even though they were

divorcing after only 5 months of marriage, she knew he would never let them down. Noé’s

father was well known in the region as he made a lot of conferences in all the hospitals. So

Noé have a lot of contacts in the hospitals and other health institutes and will be able to be

very efficient. As the job was very well paid, he accepted the position.

This is how the team was built, how the Elixir’s story began: a young team with a lot of

dreams and many competencies to help them reach their goal.

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Company Presentation

A. Elixir Ltd

Elixir Limited is an ex nihilo company specialized in preventive genetic

healthcare with a capital amount to 200 million euros. Doctors and professors will compose the

centre and so the workforce for a level of 51 % will own a major part of shares. It assures the

autonomy of the centre in terms of rights to vote and thus it’s "auto-running". The last 49 %

can belong to every investor worried of diversifying his portfolio and especially in medicine

prevention.

B. Organization

Please note that in this organizational chart Livia is also responsible for the art of living

package and Maylis for the Alzheimer Package.

Thus, as workforce, Elixir is composed by:

- 4 Responsible of each pack of Elixir’s supply

- 2 Psychiatrists who are important for following the customers

- 2 Doctors who are in charge of collecting and interpreting the DNA analysis and so on

- 3 Hostesses for welcoming and helping our clients

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C. Slogan

Two slogans represent Elixir’s vision and living art:

-“Know yourself», which refers to the DNA analysis provided in the packages and to the long

term cure.

-“Fit to your genes” in reference to the customized DNA analysis and the personalized

packages.

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Objectives

We have high objectives as our potential customers have high expectations from Elixir. The

center is trying to be innovative in different ways and our challenge is to mix technology and

disease prevention.

Corporate Objectives:

- To go international: we intend to bring our new preventive concept to worldwide customers,

to use medicines and technologies from all around the globe (Chinese medicine, world

cuisine…) and, in the future, to implement our business in other countries.

- To create partnerships with different institutions related to the health care sector (laboratories,

restaurants, Chinese medicine centers…), which will help increase our reputation.

- Long term objective: to be one of the first worldwide Innovative and Genetics Based

Preventive Center in 5 years.

Marketing Objectives:

- To gain at least 1500 new customers per year.

- To create a brand awareness for the new proposed services in the third quarter of 2009.

- To increase market share in Austrian market segment by 3% at the end of Q2 of 2009.

- To offer a “Preventive Experience & Education” to our clients (preventive medicine solutions

to a wealthy customer segment including innovative treatment and a philosophy to cure).

- To increase the patients’ awareness about DNA preventive medicine through premium

quality services and to support their concern about genetic diseases through personalized

packages.

- To use top new technologies and to increase the interest for the R&D related to any form of

preventive care.

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Start-up Analysis

The innovative concept that Elixir is trying to develop today regarding a new approach of the

preventive medicine was about a year ago just a brilliant idea of Dr. Bontemps. Soon, we have

realized the potential that this new concept may have if correctly exploited. Therefore, with the

help of our colleagues from “Start-up Success” we looked more carefully at the way we could

develop this idea. Here is the generic process that we must follow in order to transform the

simple concept in continuous revenue:

TODAY

The market analysis revealed that the most appropriate strategy for our new concept was a

niche strategy, by focusing in a first step of our business, on “haut de gamme” products

designed for wealthy people. We dare to call our approach a “one-to-one customization”.

As a consequence, the process that led us to build upon our initial idea consisted firstly in a

detailed analysis of the open market in order to emphasis our competitive advantage compared

with the existent preventive services competitors.

Secondly, given the fact that Elixir will mainly have the role of an intermediary between the

different actors that may successfully contribute to the prevention process and the interested

customers, the step of identifying the most attractive partners was also carefully elaborated in

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advance. As a result of all this upstream work, we were able to define the exact marketing

products that we will propose to our clients.

As shown bellow, the approach that we used when designing this innovative health center was

a system thinking approach through which we kept in mind at each step of our plan the whole

business cycle with its main tools and procedures.

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Data Collect.

Product def.

Country choice

Market Analysis

Communication Plan

Finance

Company Strategy

Marketing Mix

Coord. &

Control

Marketing Plan

Task breakdown

Methodology

A. Market Study

In order to understand the situation, we focused first on a global preventive healthcare

market and step by step we reduced our analysis to other main fields:

� EU and especially Austrian health market.

� Preventive healthcare centers, services and equipment market.

� Genetics Research and Development (DNA).

B. Process

1. Representation

This chart represents the different steps followed in the creation of our Marketing Plan.

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2. Product Breakdown Structure

Figure 1: PBS - Outlined Representation

0.0. Preventive Healthcare Center

1.0. Pre Project

1.1. Roles assignment and Tasks breakdown

1.2. Data collection

1.3 Product Brainstorming

2.0. Marketing Plan

2.1. Market analysis report

2.2. Marketing mix report

2.3. Strategy report

3.0. Final report & presentation

3.1. Final report draft

3.2. Class presentation

3. Responsibility Assignment Matrix

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Role Definition

Responsible This role conducts the actual work/owns the problem.

AccountableThis role approves the completed work and is held fully accountable for it.

Supportive This role provides additional resources to conduct the work or plays a supportive

role in implementation.

Consulted This role has the information and/or capability to complete the work.

4. Team Contacts

Figure 2: Table of team contacts

Contact E-mail Phone

Alexandre Aymard [email protected] 06 45 13 80 14

Pauline Dreyer [email protected] 06 59 64 32 67

Maylïs Bontemps [email protected] 06 10 46 82 12

Livia Frincu [email protected] 06 13 48 29 45

Salman Barrada [email protected] 06 86 11 33 10

Noé Nagata [email protected] 06 11 23 38 42

Xing Liu [email protected] 06 31 77 58 02

Diana Mihai [email protected] 06 63 58 05 25

C. Planning

In order to achieve our project, we assigned all team mates roles (coordinator, report

supervisor, research supervisor…) and set deadlines. We separated the tasks and scheduled

group work periods. It was essential that everyone had responsibilities in order toy help us

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to be well organized and to avoid conflicts inside the group. With this first point we could

clearly begin to concentrate the body of the project. After that, the next step was to focus on

the planning and following it.

You will find bellow a break down of tasks and a Gantt chart

1. Work Breakdown Structure

Task Sub Task Responsible Deadline

Launching or Pre-project

Data collection All 01/09/2008

Choice of the country All 01/09/2008

Product's definition All 01/09/2008

Tasks breakdown All 01/09/2008

Implementation or marketing plan

Market analysis

Supply Pauline 23/09/2008

Demand Diana 23/09/2008

Marketing mix

Products: 23/09/2008

> DNA Analysis Livia 23/09/2008

> Luxury bracelet or watch Noé 23/09/2008

> Cancer Pack Alexandre 23/09/2008

> Alzheimer Pack Maylis 23/09/2008

> Art of living Pack ("Art de vivre") Livia 23/09/2008

> Package Youth Salman 23/09/2008

Price Diana,

Maylis 23/09/2008

Promotion Noé 23/09/2008

Place (Innsbruck) Noé, Livia 23/09/2008

Process All 23/09/2008

Company Strategy

Partnerships (Dior, Hermes…) Salman,

Diana, Xing 30/09/2008

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Marketing Salman,

Diana, Xing 30/09/2008

Company Management Salman,

Diana, Xing 30/09/2008

Ethics Pauline 30/09/2008

Future: initial & development Noé, Xing 30/09/2008

Final report

Report: consolidation All 10/10/2008

Presentation: Rehearsal All 10/10/2008

Final presentation All 10/10/2008

2. Gantt chart

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Market study∗∗∗∗

A. SWOT

STRENGTHS WEAKNESSES

- Skilled and efficient labour force,

knowledge of the market.

- High quality services.

- Innovative: DNA preventive care is

combined with high technology.

- Programs customized and personalized for

each patient and disease.

- Strong community and university

partnerships.

- Focus on providing services to clients

within the most pleasant environments.

- Funding - still need further resources and

better coordination of efforts.

- Not affordable for everyone.

- Elixir infrastructure’s insufficiency.

OPPORTUNITIES THREATS

- The implantation region is a very dynamic

one with a geo-strategically position of

Austria

- Austria’s opportunities:

High health expenditure with a strong

health care system.

Well developed tourism = potential

clients.

Good country infrastructure: accessibility.

Good resources in health sector (human,

physical, technological).

Government support to preventive care

through programs and reforms.

Insurance companies beginning to support

and promote prevention programs.

- Austria is an under-populated country.

- Strong competitive market: numerous

hospitals, private clinics, and spas.

- Traditional preventive market already

developed.

- New preventive or curing treatment (i.e.

vaccine) thanks to medical R&D discoveries.

∗ All the tables in this chapter are referenced in Figure 3.

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� Opportunities

Austria - a dynamic and stable economy

- Austria is one of the most secure nations in the world. Not only when it comes to its hard

currency, but also to the business climate, the low crime rate and the stable legal system –

all coming together to create a stable foundation your business can build on.

- Austria, with its well-developed market economy and high standard of living, is closely

tied to other EU economies, especially Germany's.

- Membership in the EU has drawn an influx of foreign investors attracted by Austria's

access to the single European market and proximity to the new EU economies. Austria

also has made progress in generally increasing its international competitiveness.

- The outgoing government has successfully pursued a comprehensive economic reform

program, aimed at streamlining government and creating a more competitive business

environment, further strengthening Austria's attractiveness as an investment location. It

has implemented effective pension reforms; however, lower taxes in 2005-06 led to a

small budget deficit in 2006 and 2007.

- Austria has achieved to sustain economic growth and belongs to the richest countries in

the EU (see table 4 in appendix). After a period of low growth of only around 1.0%

annually during 2001-2003, Austria's economy recovered again in 2004 and 2005 and

grew 2.5% and 2.9%, respectively, driven by booming exports in response to strong world

economic growth.

- Austrian real GDP grew 3.3% in 2006 and 3.4% in 2007.

- The strong economic growth helped reduce Austria's unemployment rate to 4.2% in 2007

(see table 1 in appendix). Predictions are for the economy to grow 2.2%-2.3% in 2008 and

1.4%-1.9% in 2009.

- Since 1955, Austria has enjoyed political and legal stability (see table 2 in appendix).

High health care expenditures

- Total health spending accounted for 10.1% of GDP in Austria in 2006 (see tables 5 and 6

in appendix), more than one percentage point higher than the OECD average of 8.9%.

The United States is, by far, the country that spends the most on health as a share of its

economy, with 15.3% of its GDP allocated to health in 2006, followed by Switzerland

(11.3%), France (11.1%) and Germany (10.6%).

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- Austria also spends more on health per capita than the average in OECD countries, with

spending of over 3,600 USD in 2006 (adjusted for purchasing power parity), compared

with an OECD average of 2,824 USD.

- Health spending per capita in Austria increased, in real terms, by 2% per year on average

between 2000 and 2006. This was among the smallest increases across all OECD

countries during this six-year period.

- In Austria, 76% of health spending was funded by public sources in 2006, above the

OECD average of 73%.

- Spending on pharmaceuticals in Austria in 2006 accounted for 12.4% of total health

expenditure, below the OECD average of 17.6%.

A strong heath care financing system

- In 2000, social security schemes financed 43% of total expenditure; government, 27%;

user charges or direct payments, 19%; other private funds, 4%; and voluntary health

insurance, 7%.

- Public and non-profit-making hospitals that are accredited in hospital plans for acute care

at Länder level (fund hospitals) are eligible for investments and reimbursement of services

for people with statutory health insurance.

Good resources in the health sector (human, physical, technological)

- In 2006, Austria had 3.6 practicing physicians per 1,000 inhabitants (see table 7 in

appendix), compared with an average of 3.1 in OECD countries.

- During the past decade or so, there has been rapid growth in the availability of diagnostic

technologies such as computed tomography (CT) scanners and magnetic resonance

imaging (MRI) units in most OECD countries.

- In Austria, the number of MRIs increased over time from about 1 per million population

in 1988 to 16.8 in 2006. This is well above the current OECD average of 10.2 MRI units

per million population. Only Japan, the United States and Iceland report more MRI units

per capita.

- The number of CT scanners per capita is also relatively high in Austria, with 29.8 CT

scanners per million populations, compared with an OECD average of 19.2.

A strong organizational structure of health system in Austria

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- The Austrian health system is shaped by statutory health insurance, which covers about

95% of the population on a mandatory basis and 2% on a voluntary basis. Of the 3.1% not

covered in 2003, 0.7% had taken out voluntary substitutive insurance, while 2.4% were

not covered at all.

The main causes of death are diseases that may be prevented by prevention

- As in other European countries, in Austria non-communicable diseases kill eight out of ten

people. Cardiovascular diseases (CVD) account for almost one death in two; Austria has

one of the highest mortality rates for this cause in Europe, even though it has dropped by a

quarter since 1990. Ischemic heart disease is the single biggest killer, especially for women

older than 64 years. Cancer mortality is relatively low for men; for women, mortality is just

at the European average, although lung cancer is increasing. Cancer of the cervix has

recently decreased to European levels, while breast cancer is in the same range.

- Preventive care, delivered through a country's primary care system can improve all-cause

mortality and premature mortality, particularly from CVD.

- To illustrate, the table 8 in appendix shows the most significant causes of death in Austria,

ranked according to the frequency of (age-standardized) mortality of the international

classification of diseases main diagnoses in 2003. Diseases of the circulatory system

(particularly ischemic heart diseases and cerebrovascular diseases such as strokes and

cerebral thrombosis) were still among the leading. A real concern by the population has

been taken toward those diseases and more and more people have recourse to preventive

care. This concern may be illustrated with the tentative to create a medicine for the women

to prevent the cancer of the neck of the womb.

Government support to preventive care through programs and reforms

- In the form of the Healthy Austria Fund, the Federal Government has an institution which

initiates and supports focused health promotion activities.

- The Federal Government participates in international health promotion networks,

including the European network “health-promoting schools” the network “healthy cities”,

Mégapoles (involving capital cities of the EU Member States, a transnational network),

the international network “health-promoting hospitals”, the network to promote health in

companies and the European network of national institutes for health promotion.

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- As part of the Health Reform 2005, the BMGF additionally launched a new preventive

care and early detection program, and initiated the drawing up of health passes for

different sections of the population.

� Threats

Austria – an under populated country

- The population growth rate in Austria is above the EU average (3%) at a rate of 5.0% since

1990. In 2003, the total fertility rate (42) in Austria was just below the EU average of 45.

The proportion of the population over 65 rose by 0.8% to 5.7% in the period 1990–2004,

whereby a particular increase in the proportion of the male population over 65 can be

observed.

A strong competitive market

- In Austria – the development of hospitals, private clinic, spas. In addition to that, numerous

international investors are already capitalizing on Austria's advantages (see table 8 for

examples)

B. PEST

� Political

Austria is a parliamentary representative democracy comprising nine federal states and is one

the six European countries that have declared permanent neutrality and one of the few

countries that includes the concept of everlasting neutrality in its constitution. Austria has

been a member of the United Nations since 1955 and joined the European Union in 1995.

So Since 1955, Austria has enjoyed political stability (see table 9 in appendix).

� Economic

Austria is one of the 10 richest countries on the world in terms of GDP per capita, has a well

developed social market economy and a very high standard of living. Until the 1980s, many

of Austria’s largest industry firms were nationalized; in recent years, however, privatization

has reduced state holdings to a level comparable to other European economies. Next to a

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highly-developed industry, international tourism is the most important part of the national

economy.

� Social

The life of every Austrian today is protected by a comprehensive system of social security and

welfare schemes which are essentially the product of the struggle which the country's

industrial workforce and its representative organisations have waged for a century and a half

to safeguard and improve their working and living conditions.

As a consequence, Austrians enjoy a very pleasant social environment: rich culture,

environmental quality, high living standards, security, classic or highly modern. World

Competitiveness Yearbook 2007 ranks Austria number 1 in quality of life (see table 10 in

appendix).

� Technology

The importance of environment technologies as an economic factor in Austria was first

analyzed in detail in 1995 by the Austrian Institute of Economic Research (WIFO) on behalf

of the (then) Federal Ministry of Economics and Labor. The implementation of the EU

Environment Acquis in the EU accession countries provides an additional market potential

and a further challenge for the Austrian environment technology companies.

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C. Open Market

1.1 Potential market in Austria and near Innsbruck

� Innsbruck

We plan to open our center in the city of

Innsbruck in Austria. The city has 126 000

inhabitants, and 272 000 inhabitants if we

take into account the suburbs. This could

be our first target on the market. It is a

quite big (104, 91 km²) and interesting

city, and the population is growing

steadily as you can see on the chart on the

right.

The city receives a lot of tourists. Tourism is the most important source of income for

Innsbruck, as there are many infrastructures available for tourists and a lot of activities offered

during the winter as well as during the summer.

Innsbruck is well served by different transportation infrastructure. It is linked to Italy,

Germany and Switzerland with freeways that allow easy access to the city center.

The city also has a railway station and an airport that are both very frequented and well

served.

� Tyrol

Innsbruck is located in the “Land” of Tyrol (in

grey on the map). This land has nearly

687 000 inhabitants. It is one of the most

known and rich region of the country.

Tourism is very dynamic in Tyrol, and the

level of purchasing power increases the

potential of our open market in this region.

10% of the richest inhabitants receive 20% of the total income. We can admit that those rich

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people might be interested in our center. We would then extend the target to the whole

country, that is 8 million people.

� Lichtenstein

Lichtenstein has 35 400 inhabitants. It is a very small country, but also quite rich and

therefore another potential market for our center. The business community is well represented

in this country which means that at least 10% of the population could be interested by our

services. The GDP (nominal in 2005) is of $105, 323 per capita, and the GDP (in PPP that

same year) reaches $53,951.

� Germany

There are mainly two “Länder” in Germany that we

would try to reach at the beginning of our activity. The

first one is Bavaria (N°2 on the map below). It is the

biggest one, and the second one in terms of population:

it has 13 million inhabitants. The second one would be

Saxony (N°13 on the map below). This Länder has 4

million inhabitants with Dresden as its main city. We

could target 17 million inhabitants at the beginning of

the activity and find our customers among the richest

persons of those regions. Thereafter we would like to

target the whole country, so 82 million of inhabitants.

Germany is a very interesting market for us. It is the

largest national economy in Europe, and 4th in the

world with an important number of wealthy people.

For example, the GDP/inhabitant in Bavaria is of €32 800, and of €34 000 if we take into

account the whole country. The HDI is high: 0.935.

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� Italy

On proximity basis, our company will first target Venetia Giulia – 1,2 mil inhabitants (N° 6

on the map below), Alto Adige – 1 mil inhabitants (N° 17 on the map below) and Veneto –

4,9 inhabitants (N° 20 on the map).

On a revenue basis Veneto seems to have the

greatest potential given the fact that its main city,

Venice is attracting numerous tourists each year,

wealthy people willing to spend their money on

their well being and, why not, special preventive

treatment. We could therefore estimate

approximately 7 million Italian inhabitants (and

foreigners visiting Italy) for our center in the

customer catchments area. We would then extend

the target to the whole 60 million of Italians, among

which we will target the wealthiest people.

Italy has a high GDP per capita (nominal): $35,386 as well as the HDI (0,941). The Gini

coefficient is medium (36) and it indicates the existence of an equality gap between the very

poor people and the very wealthy, again a sign of potential market for our services.

� Switzerland

We would first target the “Canton” of Graubünden (see on the map of Switzerland) thanks to

its proximity with the Austrian borders. It is one of the biggest regions of Switzerland

counting more than 190 000

inhabitants with the city of Chur

as its capital. We would, like for

the other countries, extend the

target to the whole country. It is

well known that the living

standards are very high in

Switzerland; as a consequence,

our aim is to acquire as much as

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possible of this 7,6 million inhabitants market in the first year.

Switzerland has a stable, modern, and one of the most capitalist economies in the world. The

nominal per capita GDP is higher than those of the larger western European economies and

Japan, it ranks 6th. The World Economic Forum's Global Competitiveness Report currently

ranks Switzerland's economy as the second most competitive in the world. For much of the

20th century, Switzerland was the wealthiest country in Europe by a considerable margin. In

2005 the median household income in Switzerland was an estimated 95,000 CHF, the

equivalent of roughly 55,000 USD in purchasing power parity, which is similar to wealthy

American states like California and Vermont. The HDI is very high (0.955) and the Gini

index is medium (33.7).

� Total potential market

To summarize, our aim is to first target the closest geographical areas such as: the city of

Innsbruck, the region of Tyrol, Lichtenstein, Bavaria, Saxony, Venetia Giulia, Alto Adige,

Veneto and Graubünden. These regions represent a 25 millions people market with a high

possibility of attracting at least 8% of them.

We would then extend the target, (i.e. the marketing campaigns), to the rest of the regions of

these countries (Austria, Germany, Italy and Switzerland), which would increase the size of

the market to nearly 158 million prospects.

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1.2 Disease market on the targeted markets

� Cancer

The number of cancers per 100 000 inhabitants is quite high and it is increasing in most of the

countries (see table 11 in appendix). In Austria it reaches more than 450 persons and this

number is increasing steadily. It is quite alike in Germany, where there are more than 500

persons out of 100 00 that have a cancer. The situation in Switzerland is even more surprising:

the disease touches nearly 1250 persons each year. The only country where the number of

cancers decreases is Italy.

� Cardiovascular diseases

In 2006, 28 900 persons died because of cardiovascular diseases in Switzerland. This number

is worse in the other countries, as it reaches 35 000 persons in Austria, 388 000 in Germany

and 279 000 in Italy. This number is not improving because of increasing consumption of

alcohol, and increase in obesity cases for example.

� Alzheimer

It is estimated that 47% of people who reach the age of 85 have this disease, 18.7% between

75 and 84 years old and 3% of those aging 65 to 74. Apparently the incidence for Alzheimer

is also increasing for younger persons between 40 or 50 years old. It is the fourth leading

cause of death after heart disease, cancer and stroke. According to the latest research at the

8th International Conference on Alzheimer's disease and Related Disorders, Alzheimer's

disease cases may triple by 2050.

� General improvement of health care, increase in the prevention

The number of regular smokers varies a lot in time and space (see table 12 in appendix). As it

depends a lot on the “fashion trends”, the number of the persons who smoke fluctuates a lot in

time. Nowadays, thanks to numerous aggressive campaigns against this unhealthy habit, the

number of smokers is decreasing in most of the countries. Only in Italy this number is

increasing but it remains quite low (less than 23% of the population). This number is the

lowest in Switzerland and it is continuing to drop dramatically (22% at present). It is the

highest in Germany where it reaches 34% but here too it is steadily decreasing.

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These decreasing numbers show an increasing concern of the population for their health. All

the governments have increased their prevention budgets. As you can see on the chart below,

more and more Austrians have appealed to preventive check ups, the same can be observed in

other countries. The increase of preventive check ups is of nearly 6% per year (see table

bellow).

� Potential target by income

We admit that in those geographical areas, the sharing out of the income is as follows:

Our business would try to reach exclusively the high level management. We would therefore

forecast to target 8% of the population in the geographical areas we have chosen.

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On our short term plan, we have 25 million of inhabitants we could reach. If we take into

account that 8 % of the population should be the heart of our target, we then have 2 million of

prospects.

On the long term plan, we wanted to target the whole countries, so 158 million of inhabitants.

We would then have 12.64 million prospects.

We represented in the diagram above our forecast for our business in several years. We

decided to show different scenarios. The most plausible scenario is in fat.

First of all, we plan to make a well targeted marketing campaign. This campaign will reach

some of our potential customers. We think that the campaign will allow us to be known by at

least 0.5% of our 12.64 million prospects target. In the best forecast it would be 1.2%.

Then in the small percentage of prospects that will know us, a small part will effectively come

to our center and become a customer.

After the first years of our business, we think that with a good marketing mix, we could be

known by 1.2% of our long term target, so 151 680 persons. Out of these 151 680 potential

customers, we forecast to have 1517 customers per year, so nearly 1% of the prospects.

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Strategy

A. Forces analysis – Porter’s Network Model:

The framework is important in order to see all the pressures and difficulties that Elixir will

have to deal with. In this Porter framework, we may presume that the strongest force that Elixir

will have to face is new entrants. They are numerous on the market and they can become a real

threat to it. To attract the Government and the citizen attention, Elixir will have to take into

account every critical success factor that final users seek.

Our business is highly dependent on:

• Labor : As our business is to provide customers with personalized preventive advises

about their health, we are dependent on the labor factor (8 associated preventive

advisers). In order to keep our labor force motivated, loyal and satisfied, we choose to

associate our critical labor force in our business. Our association model is to give to

each of our preventive advisers the same number of shares. This will ensure that every

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associated preventive adviser will detain the same power inside of the corporation.

Each associated adviser will be the equal of another adviser. Moreover all the

associates will receive at the end of the business year a part of the corporations benefits

calculated on their personal results. This is another motivation factor for them, it will

create competition between them, and stimulate them to increase their personal results.

• Science and Technology: As our core business is to deliver advises to customers based

on the latest technological and scientific research, we are dependent on the reliability of

this factor. We have to make sure that the technologies and scientific researches on

which we base our work are the most efficient and most secure for the customer. This is

why we choose to work only with top laboratories and top researchers in order to

ensure the quality of our advices and products.

• Suppliers: In organizing the supply of the corporation we choose to select a panel of

different laboratories and partners in order to lower the risk that we could lack of any

supply for our company.

B. Ansoff Matrix Analysis

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• Bracelet: Based on RFID technology, the bracelet will be a storage space for the DNA

information. The used technology is available and already used for several years; it is

the combination of DNA information and RFID technology in a bracelet which is the

new product. As we will act as an intermediary, and delegate the conception of the

bracelet to our partners, we will have a low resource implication for the company which

means also a lower risk.

• Packages: Our business is to provide our customers with health preventive advice in

order to avoid diseases and extend their lifespan. There are already existing products on

the market to act against this diseases and aging. Our goal is to give personalized

advises to the customers considering DNA analysis and other techniques and direct

them to the adapted products. The targeted customer is a person which is interested by

preventive medicine and has a high income. Our market study has revealed that every

year there is an increasing interest for preventive medicine in our targeted area (+7%)

and that 13.6 % of the 25 million persons living in the area have a high income level.

This facts show us that there is a real interest for preventive medicine and that the area

has a real chance to provide us with potential customers for our business.

• DNA Analysis: DNA analysis is a tool already used in the legal field (domain of

justice) (criminality, paternity, etc…) and also in research and clinical analysis. The use

of this technology is accessible to a large panel of customers who can afford the price

of the test which is about 300 €. Our idea is to combine the analysis with an advice

phase adapted to the needs and desires of the customer. As a consequence we use an

already existing technology and through our expertise and advices we will try to

respond to the requirements of the customer.

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C. Segmentation

• Considering the geographic location of Innsbruck we identified 25 million of people

coming from the border regions of Austria from Germany, Lichtenstein, Italy,

Switzerland and France.

• 13,6 % of this population has a high level of income and represents our target.

• In order to define the kind of customers who could be interested in our products we

started a market segmentation analysis.

• We have chosen 2 factors in order to show our targeted customers:

– a “demographic” criterion, which is the income level

– a “behavioral” criterion which is the preventive behavior

• In combining both factors we can clearly define our target

– High income persons because they are the most concerned about their health

and have a high preventive behavior.

– Boomers between the ages of 45 to 55, generally healthy, who hold key jobs or

run companies. We are targeting executives, entrepreneurs, men and women.

Those over the age of 60 tend to come as a couple.

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D. Maslow’s hierarchy of needs

The purchase of a product or service is very often the consequence of a need. According to the

theory of Maslow, the consumers have a limited number of fundamental needs, which can be

organized into a five levels hierarchy. Our centre matches the following needs of this pyramid:

Physiological needs

Even if our key services rely on preventive medicine, the centre provides a large range of

others services through our different partners such as restaurants or hotels.

Safety and Security

As the centre helps people to avoid developing some diseases, we match these needs by

improving their health and so by increasing their feeling of security.

Belongingness

As our services are reserved to wealthy people the fact that you access our centre makes you

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part of a certain community. We try to develop our customers’ feeling of belongingness and so

their loyalty. The bracelet we give to our clients is the symbol of the community created by

Elixir.

E. Blue Ocean

Prevention medicine market

0

10

20

30

40

50

60

70

80

90

proxim

ity

acce

ssibi

litypr

ice

servi

ce

quali

ty

tech

nology

presti

ge

custo

mizatio

n

criteria

leve

l

Elixir

competitors

ERRC Grid

• Eliminate: - Proximity

• Reduce: - Accessibility

• Raise: - Price - Service - Quality - Technology

• Create: - Prestige - Customization

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We have identified eight criteria on which to play in our business.

The first one is the price. We know that with our technology the price will be much higher

than the one of the competitors. This is in compliance with our high income target. The

second criterion is the service. We will provide a high number of services which will make

our customers feel special, and make him feel that the price he is paying is really worthing.

Of course the quality of our products and services will be higher than the competitors’ to

justify the price. Everything we will provide will have to be state-of-the art. We will also use

the latest technologies so compared to our main competitors our level of technology will be

higher. The customers will feel safer and more special. Given the price and the high quality of

services provided, our center will not be accessible to everyone. This complies with our

strategy of making the client feel unique. Our level of proximity will be quite low as we will

be geographically quite far away from some of our customers. He will come from other

regions or even other countries to spend some days in our center or our partners’ hotels.

We also decided to play on two new criteria that do not exist or are slightly represented on the

current market.

The first one is the prestige. While preventing themselves from being sick, our customers will

feel that they are in the center of the whole process. They will have the feeling they belong to

a club hardly accessible for people who do not belong to their wealthy world. They do not

want to be mixed with the rest of the population.

We will also make them feel distinctive thanks to the customization criterion. Every single

product we will sell will be adapted to the customer and to his genes. We will have a

particular follow up and the products or services provided will be customized.

All our criteria are in agreement with our strategy and will enable us to differentiate ourselves

from the competitors. The last two ones will allow us to bring something new and needed on

the market, and will grant the success of Elixir.

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Marketing Mix

A. DNA analysis

"Genetic testing taken together with the patient's medical history, current diagnostic

procedures and counseling interviews provides an effective and comprehensive tool for the

creation of individual therapy and prevention concepts."3

Professor Gerald Gitsch, Director of the Department of Obstetrics and

Gynaecology, Freiburg University Medical Centre, Switzerland

Our products are defined as a set of “prevention packages” which try to combine the modern

medicine with the traditional one and the living style of our customers. At the origin of each of

these marketing products there is a DNA analysis.

It is well known that each one of us has a unique combination of genes, like a genetic ID. This

one can be identified through a series of tests made by specializes laboratories all over the

world.

The procedure is very simple. The patient is asked to provide a sample

of blood, hair, skin or any other body fluid or tissue. This first step can

be easily done at home these days given the increasing number of

companies which propose self DNA testing kits (i.e. DNA testing, DNA

Solutions, Lab Genetics, Easy DNA etc.).

The sample is afterwards sent to a specialized laboratory. Thought this analysis our specialists

will first of all create the genetic map of the patient, which means identifying the exact

sequence of the chromosomes that he/she possesses along with all the possible anomalies (a

missing or added piece of a chromosome, an altered chemical base, a misplaced piece of

chromosome etc). The results will subsequently enable other related processes such as:

• An early detection of susceptibility for certain diseases even before the first symptoms

• Individual measures for prevention and therapy for diseases

• An optimisation of life style and therefore life quality

3 “Genome profile to predict diseases “, Gulf News, Dubai, March 15, 2003.

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• A slowdown of ageing due to an individualized nutrition and choice of nutrition

supplements

There is a vast range of DNA tests available these days depending on the main purpose of the

procedure: predisposition for a certain disease (Figure 1), paternity identification, gene

mapping, etc. Our centre will provide, in a first stage, a gene mapping analysis, which is a

general but complete DNA test. Given our partnership with Swarovski Research Laboratory

any other additional tests may be provided after a first interpretation of the results, if necessary,

tailored on the patient’s needs.

In order to have a broader vision of the customer’s genetic heritage and the risks to which

he/she may be exposed, two special trained physiotherapists will complete the DNA results

with a “genealogical tree” type analysis. Through appropriate questions they will recreate the

genetic history of the patient’s family which has a significant impact on the genetic map of the

patient himself/herself.

B. Products

1. Art of Living Pack

The package “Art of living” is addressed to all those who, following the DNA test, the results

indicated the presence of some chromosome anomalies which can lead, with a certain

probability, to several common diseases such as cardiovascular diseases, obesity or diabetics.

� Genetics and the cardiovascular diseases

Studies have shown that over 5% of all catalogued genes have some effects on the heart and

that hundreds of them are expected to be essential for normal development and physiology of

the cardiovascular system. In fact, there are three main factors that may contribute in different

proportions to one of the form of this disease:

o Environmental Risk Factors

o Genetic (or Inherited) Risk Factors

o Chance

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Most cardiovascular diseases are a result of multiple abnormalities in many different genes on

several chromosomes. For example, hypertension appears to be related to up to 20 genes:

o Renin-Angiotensin System

o Kallikrein System

o Nitrous Oxide System

o Membrane (Ion) Channels

o Catecholamines

o Cardiovascular Peptide

o Neuropeptides

This package starts from the premises that “You can’t change your genes, but you can change

your behavior”. As shown above, studies have proved that the environmental factors such as

the diet, the physical activities or the stress have a relatively important impact on the genetic

predisposition for a certain disease. The specialists speak about a “gene-environment

correlation”4 which is at the core centre of our package “Art of Living”.

“Art of Living” is a multi optional package. Given the link between the 3 main diseases that it

addresses, our patients will be able to choose from the different services and goods included in

this pack those who will fit the best their needs. The probabilities identified in the DNA

analysis will serve as the main criteria in choosing the appropriate options.

� Treatment

Personalized diets by nutrigenomics experts

Nutrigenomics is the science that examines the response of individuals to food compounds

using post-genomic and related technologies (e.g. genomics, transcriptomics, proteomics,

metabol/nomic etc.).

4 Plomin R, DeFries JC, and Loehlin JC, "Genotype-environment interaction and correlation in the analysis of human behavior". Psychological Bulletin, 1977, page 309–322.

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Figure 1 - Nutrigenomics mechanism

Source:http://www.nugo.org/everyone/24023

Our nutrigenomics experts have a “system biology” thinking and a much broader view over the

patient’s need in terms of diet that the classic nutritionists. They are able to create a personal

diet program for each of our clients by combining his/her genetic map with the record about

his/her lifestyle.

Physical activity program: “Fit to your genes”

Through our different partnerships, our centre will propose to its clients a large variety of

physical activity programs in order to prevent a negative correlation between the identified

probability for developing a certain disease and the environmental factors, more precisely, the

patient’s behaviour.

“Cuisine du monde” ateliers

In “self care” optics, our centre offers to its patients the possibility to learn about the healthiest

dishes from all over the world and even how to prepare them, from our specialists. In

partnership with four stars restaurants, these ateliers are meant to educate our patients about

how to eat healthy and how to avoid classical harmful aliments in a pleasant way and with a

long term impact.

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Therapy

The stress is one of the main environmental factors that may increase

the risk of each of the 3 diseases addressed by the “Art of Living” Pack.

As a consequence, we intend to offer to our clients a set of therapies

that could help them to prevent any damaging effects of this factor. In

partnership with spas, we will have the possibility to include in this

pack thermal water programs, aroma therapy, massage and sauna

programs, etc.

Chinese Medicine

Following the newest trend in the prevention of the cardiovascular disease in Western

Medicine, we have included in our “Art of Living Pack” a traditional Chinese treatment with

Chinese Herbs.

We will propose to our patients:

- Natural medication such as the Cardiotonic pill (CP), a drug which contains the medical

herb Salvia miltiorrhiza bunge, widely used in Chinese hospitals for the prevention and

management of ischemic cardiovascular diseases created by our colleagues at Monash

University (Australia)5.

Huatuo Zaizao pill - a pure natural preparation from

plant origins for treating and preventing

cardiovascular and cerebrovascular diseases and

apoplexy and hemiplegia, stroke, poor blood

circulation, numbness, stiffness in one's limb,

difficulty speaking or deviating of eyes and mouth.

Huatuo Zaizao pills improve the immunologic

function of the body and tolerance of the brain tissue.

5 Dr. Paul Komesaroff of Monash University in Victoria states that, “While further study is required, there have been beneficial effects. CP appeared to exert a mild inhibitory effect on DNA synthesis and proliferation of endothelial cells. Further, CP inhibits expression of ICAM-1 and VCAM-1 in EC and inhibits proliferation of vascular smooth muscle cells.”

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- Chinese formulas for heart qi vacuity (ex: yang xin tang, shen xian tang, etc), heart blood

vacuity – ex: gan maid a zao tang: nourishes the heart and quiets the spirit, harmonises the

center and relaxes tensions or urgency, heart yin vacuity –ex: tian wang bu xin dan:

nourishes the blood and enriches yin, supplements the heart and quiets the spirit, heart yang

vacuity, etc.

Self Care

In the optics of educating our patients in order to improve the performance of the other

preventive health care packs that we offer to them, our center proposes a complete kit of self

care. This will contain the most efficient and easy to use self diagnostic tools, self monitoring

devices and multi-media self care items. The patients will benefit from a self care training

course before using this mini pack in order to insure the correct use of these devices.

2. Alzheimer Pack

Alzheimer’s disease Reminder: It is “a form of dementia, a global neurological impairment

characterized by slowly progressive and irreversible deterioration of the cognitive functions-

speech, abstract through, emotion, memory- and hence the ability to take care of oneself, to

identify time and place, to relate socially to others, to think and speak”6.

� Alzheimer & Genetics

Alzheimer is not only linked to DNA. There is in many cases a relation between Alzheimer and

DNA. It has been proven that Genes account for 58% to 79% of a person's risk of developing

late-onset Alzheimer's.

However, there are many other risk factors such as:

- Age: older people are more likely to be affected

- Sex: women are more likely to be affected than men

- Other: Race, profession, geographical, head injury problems

6 http://fr.wikipedia.org/wiki/Maladie_d'Alzheimer

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There is no existing preventative or curative treatment.

Drugs exist, which can help alleviate certain symptoms such as agitation, anxiety, depression,

hallucinations, confusion and insomnia.

� Treatment

Therefore, we had to develop an innovating service which took into account the fact that

Alzheimer is a diseased not always linked to DNA, and that no Research treatment or method

to cure it.

We do not predict for patients miraculous recovery but a long term treatment based on both

DNA medication and self cure.

Check Up / Diagnosis

This first phase consists of multiple testing, which are linked to Alzheimer’s risk factors.

These are:

- Medical History

- Mental Status Evaluation

- Physical Examination

- Neurological Examination

- Neuropsychological Evaluation

- Brain Scans

- Laboratory Tests, etc.

All tests are done since years in hospitals and laboratories. We will work with the best of

theses hospitals in Austria.

Our treatment will then consist of therapy & future prevention.

Therapy

In order to be efficient, we have set the treatment three major aims are:

- Improve the quality of life for the person suffering and for his or her caregiver(s).

- Slowing the progression of cognitive decline and treating specific symptoms and/or co-

occurring conditions with drug therapies.

- Managing the behavioral symptoms of Alzheimer's.

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We have selected two relevant kinds of therapies:

Chinese medicine7

In Chinese medicine, Alzheimer's disease is not yet recognized as a separate disease entity.

Instead, it falls under the generic category of senile dementia. One examples representative of

the standard professional Chinese medical treatment of senile dementia is liver depression qi

stagnation mixed with phlegm & stasis pattern.

Symptoms: Heart vexation, easy anger, depression, oppression, and emotional dysphoria, no

desire to speak, bilateral rib-side distention and pain, a dark tongue with possible static

macules and slimy fur, and a bowstring, slippery pulse. Treatment principles: Course the liver

and rectify the qi, quicken the blood and dispel phlegm.

Indian medicine8

Research has proven that a dietary staple of India, where Alzheimer's disease rates are

reportedly among the worlds lowest, holds potential as a weapon in the fight against the

disease. Reporting in the Dec. 7, 2004, online edition of the Journal of Biological Chemistry,

the research determined “curcumin is more effective in inhibiting formation of the protein

fragments than many other drugs being tested as Alzheimer's treatments”.

� Future Prevention

Treatment for Alzheimer's can vary from person to person. Because Alzheimer is linked to

different factors, our service will take into account the risk factors by which the person is the

most affected and treat him/ her following theses risks.

Non-drug approaches to treatment will be chosen with our center doctors and coaches. This can

be for example a new diet, practice of a sport, relaxation classe.

7 http://www.encyclopedia.com/doc/1G1-87719988.html http://findarticles.com/p/articles/mi_m0ISW/is_2002_July/ai_87719988 8http://alzheimerdiseaseinindia.blogspot.com/2007/04/indian-curry-may-be-next-alzheimers.html http://www.news-medical.net/?id=7047

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The centre will also provide patients with a long term Alzheimer prevention schedule. This

schedule is adapted to the need and to the symptoms of each patient. This schedule will

include:

- Psychological support, with psychologists specialized in Alzheimer’s.

- Reeducation & stimulation exercises: For example, the patient will has to do on regular

basis Memory refreshing exercises.

- Lifestyle therapies: These include various strategies aimed at managing problematic

behaviors, including involvement in therapeutic activities, home or "environmental"

modifications, and the use of appropriate communication.

- Maintaining overall health through regular medical care, proper diet and exercise, and

using complementary health approaches as appropriate to address specific health needs.

- Support and education for the family and caregiver: this will be done through Family

Meetings. As families of individuals suffering from Alzheimer's are affected by the

disease, they should meet on a regular pattern doctors in order to learn how to handle

the disease.

3. Cancer Pack

� Cancer & Genetics

As we said before cancer is one of the most deadly diseases that is why huge researches has

been engaged in order to find its main sources. Some scientists argue that the origin of that ill

is genetic whereas other disagree saying that the main causes to it are environmental.

To end this quarrel, Swedish researchers studied twins comparing the frequency of their

cancers. If most of the twins are both affected by the same cancer, the balance tilts for a genetic

predisposition. If, on the contrary, only one is affected, the environmental influences are

dominant. 44 788 twins had been studied by Paul Lichtenstein and his colleagues. Results have

shown that globally a cancer on four relies on genetic factors. Three others would be the

consequence of our lifestyle.

Considering this typology, the centre will provide services to know and avoid this disease:

- DNA analysis

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- Family History’s Analysis

- Check-up (scanning)

- Advices & prevention

� Treatment

Check-up

Considering the results provided by our DNA analysis and considering the level of risks’

assessment, the centre will make a complete check-up of the patients in order to know if there

is no sign of tumor through9:

- Skin exam

- Pap smear

- Complete Health Examination

- Pelvic Exam

- Testis self exam

- Endometrial Biopsy

- Clinical breast exam, Mammogram

- Digital rectal exam

- Stool blood test

- Prostate specific antigen (PSA) blood test

- Colonoscopy

- Double-contrast barium enema (DCBE)

- Endometrial biopsy

Tests will be chosen depending on the patient’s age, the level of risks and each kind of cancer’s

predisposition, which is diagnosed due to DNA analysis.

These tests will be updated each year thanks to partnerships with active Research and

Development Centers such as:

- National foundation for cancer research

9 http://www.mamashealth.com/cancer/cancerdet.asp

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- Agency for healthcare research and quality

- National Cancer institute

“Biomedication”10

This section is based on the researches of Mirko Beljanki a biochemist and biologist, who

spent his professional career at the Pasteur Institute, Paris, studying the causes and mechanisms

occurring during gene activation, cell division and tissue development in both normal and

malignant states.

His results led him to the invention of the Oncotest, which allowed him to identify many

molecules having a carcinogenic potential. This Oncotest permitted Dr. Beljanski to discover

two specific anticancer plant extracts. These products can be obtained from Natural Source

International, Ltd11.

- Prostabel®: it is an innovative and all natural blend of Pao Pereira (Pau Pereira) and

Rauwolfia vomitoria extracts that specifically promotes the health of prostate cells, an

essential factor in maintaining normal prostate function.

10 http://www.beljanski.com 11 http://www.natural-source.com/francais/products.php

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- Ladybel®: through its regulatory or normalizing effect on cellular enzymes, golden leaf

Ginkgo extract enhances the natural cell repair process and helps the tissues to remain

healthy, even when they are exposed to extreme physiological stresses.

- Pao V®: it supports the body’s natural defense system, creating the conditions for

normal physiological processes and, to some extent, helping the body’s own immune

and detoxification system to eliminate or neutralize undesirable cells.

- Rovol V®: it supplies a selective extract from the bark of the roots of Rauwolfia

vomitoria, an African shrub traditionally used as a gentle laxative and a regulator of the

hormonal system.

- ReaLBuild®: it supports the body’s immune system to help boost the cells which

naturally enhance the generation of white blood cells and platelets

Chinese medicine12

The traditional Chinese medicine obtains very good results against cancer by keeping the

double initiative of prevention and treatment and by remaining always worried about the global

balance of the human being, such as it is defined by the theory of the Yin Yang and such as it

results from modern scientific researches. In our structure we have developed several

techniques issued from the Chinese know-how such as:

- Acupuncture and aural acupuncture: it is a technique of inserting and manipulating fine

filiform needles into specific points on the body with the aim for therapeutic purposes.

According to traditional Chinese acupuncture theory, these acupuncture points lie along

meridians along which qi, the vital energy, flows.

12 « La médecine traditionnelle chinoise et le cancer/Prévention et traitement », Dr Yongfu Xu

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- Natural remedies: all our well chosen herbal remedies source from experienced and

authoritative experts, and have been most commonly recognized by the practitioners in

this field.

- Moxibustion: Practitioners use moxa to warm regions and acupuncture points with the

intention of stimulating circulation through the points and inducing a smoother flow of

blood and qi.

Indian Medecine

This section is meanly based on an antique Indian remedy called Ayurveda13. Scientists at the

University of Pittsburgh Cancer Institute assume that its herbal products slow down the growth

of tumors. Ayurveda, a long standing Indian remedy is made up of the fruits of three plants,

Harada, Amla, and Bihara that have been dried and powered.

4. Youth Pack

� Aging and genetics

The causes of disease and aging are multiple, but at the individual level, there is a common

biochemical denominator resulting from the summation of genetic, behavioral and

environmental factors: oxidative stress, which is defined by an unbalance between an excess of

reactive oxygen species (ROS) and the antioxidant defenses, but also the decrease of the

growth hormone level in human body.

By prevention and changes in behavior which need to be reached early in life, by education we

can increase the lifespan of each person. The aim of anti-aging medicine, is trying to find the

roots of chronic diseases and aging, and act against it.

� Treatment

Check up

- Test your biologic aging rate and status on four levels from the physiologic to the

cellular, molecular and genetic DNA levels

13 It is said that Ayurveda is translated from ancient Sanskrit and means knowledge of life.

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- Determine your biomarkers of aging through computer driven testing programs, and

using blood levels, body composition, including tissues, fluids, and hair, and include in

this scientific modeling, your emotional patterns, exercise habits, and stress factors.

- Determine your total hormone profile more analytically and comprehensively,

measuring the Precise levels of total and free hormones are determined and then

quantitative ratios are calculated.

- We assess your complete anti-oxidant status, degree of muscle atrophy, loss of strength

and skin elasticity, bone demineralization, depression of your immune responses, and

lowered neural reaction time. And, we can begin to measure some attributes of lowered

cognitive functions such as age-related memory loss.

Medication

Aging treatment may include a highly individualized nutritional, hormonal, and

pharmacological therapy. Intervening in the aging process may involve a mix of anti-oxidants,

hormones and free radical scavengers that stimulates your body's own maintenance and repair

processes.

- Personalized solutions: (i) to re-establish a normal redox status by appropriate

supplementation of antioxidants, (ii) to reduce the role of chronic

infection by micro-organisms. A rational use of antioxidative regimens,

adapted to each person (there is gene polymorphism of our antioxidative

enzymes), and monitored by measurements of parameters of oxidative

stress in blood or urine (peroxidized lipids, oxidized DNA bases, level of

reduced glutathion, etc.) has clinicaly shown good results.

- Appropriate regimen (food + supplements) should be prescribed until

biochemical monitoring shows disappearance of oxidative stress and the

rebalancing of the biochemical levels of the customer.

- Hormone replacement therapy which strives to recreate the youthful

balance of hormones in the body shall be used. For example using DHEA,

this hormone is metabolized into other hormones, supplementing with DHEA

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may allow the body to choose which hormone is needed, then synthesize that hormone from

the available DHEA. The results show to have individual benefits improving life quality,

lowering cholesterol, burning fat, and boosting the immune system.

Seminars and control

Checking up the general health and the results of the treatment will be done once or twice a

year with the customer. During this check up a general assessment of the health of the

customer will be done and if necessary an adjustment of the treatment will be undertaken.

The customer will be also invited to the educational seminars that are designed to present the

results of research and new products.

5. Bracelet/Watch

In addition to our products, each of our customers receives a bracelet or a watch when

subscribing. The bracelet/watch given to our customer, using the latest technologies has several

important functions in order to complete our services, and constitutes an added value compare

to our competitors.

� Functions

- The bracelet is equipped with a RFID tag stocking our customer’s personal information

such as DNA analysis result, blood type, allergy, diseases in the past, recent treatments, etc.

This ability enables getting better treatment by avoiding, for example, risks of allergy.

Note that this function is extremely helpful in case of emergency, since it avoids the waste

of time on analyzing the patient.

- The bracelet permits the automatic updating of our customer’s data in our registered

partners. This function allows our specialists to follow faster and easier our customer’s

progress and needs during the treatment.

- In our registered restaurants, the chef gets information about our members and proposes

menu adapted to the treatment of each of our customers.

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We use the RFID (Radio Frequency IDentification) technology which is suitable to implant in

a accessory thanks to its small size (for example Hitachi’s RFID tag measure 60 microns, that

equals to 0,00006 meters, which is enough to board a 128 bits ROM) and because it can go

through materials and therefore, doesn’t need to be expose directly.

We use rewritable passive low-frequency RFID tags since data are updated on a regularly pace

and the tag is located close to the skin.

(For more information about RFID technology see figure 4)

� Design

Our bracelet/watch is an extremely important device in order to complete our services.

Therefore, we need our customers wearing it systematically in order that they can benefice our

services at any moment. For this reason, we need our customer “loving” our bracelet/watch. In

order to satisfy this necessary requirement, we developed a partnership with the renowned

French jeweler and watchmaker CARTIER, and created a new collection especially for Elixir’s

customers. This new collection available for bracelet and watch is characterize by the fact that

it could be customize to our customers taste; in other words, our customers are able to create

the “bracelet of their dreams” by participating to the design of their accessory.

The development of a new collection thanks to a partnership with a famous jewelry maker is

not only an opportunity to satisfy personal ego, but also provide a feeling of belongingness to

the Elixir community.

For men

BRACELET

Our customers have the choice of the form and of the material between platinum, yellow gold

and white gold. The tag is integrated inside the bracelet so that the bracelet looks like a normal

bracelet and is waterproof.

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WATCH

We selected automatic quartz watches for extreme time precision and life expectancy and our

customers have the choice of the material between: platinum, yellow gold, white gold, steel

and titanium. The tag is integrated inside, therefore the watch is waterproof.

For women

BRACELET

Our customers have the choice of the material between platinum, yellow gold and white gold,

and could personalize it by combining stones such as diamonds or precious stones. The tag is

integrated inside the bracelet so that the bracelet looks like a normal bracelet and is waterproof.

WATCH

We selected automatic quartz watches for extreme time precision and life expectancy and our

customers have the choice of the material between: yellow gold, rose gold, white gold and

titanium. The tag is integrated inside, therefore the watch is waterproof.

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Some of our customers might want to keep their current bracelet or watch and use it as their

RFID tag accessory. Therefore, we are also able to transplant the RFID tag to our customers’

bracelet or watch.

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C. Promotion

We identified various place and media for promoting Elixir’s services. We promote our

product by 3 channels:

1. Through posters, brochures and movie

In European airport lounges close to Austria: (partnership with the Priority Pass program)

Members of airport lounges are most of the time executives who are traveling around the world

and who are looking for a moment of relaxation and unwind, in their stressing environment.

Those people have often an irregular life rhythm and an unhealthy lifestyle, which could,

combine to the large amount of stress, lead to some diseases afterwards. Our objective is to get

the attention of some of those executives, caring about their future.

(Priority Pass program is the largest accessible lounge coverage worldwide with more than 500

lounges in 90 countries in 275 cities and 1.5 millions members).

In European golf courses close to Austria: Golf Course Advertising

Golf is one of the activities preferred by upper income class. We try to attract people who

would like to be healthy in order to be able to continue playing golf.

There are 66 courses in Austria, 138 in Germany, 91 in Italy and 31 in Switzerland according

to GolfCoursesGuide.org14.

In our registered partners: sports clubs, hotels and restaurants

2. Through people

Sponsorship system

We promote our products through our members, since in wealthy people’s network, people are

intimately associated and “everyone knows everyone”. The process is that when a member

patronizes a new customer, he/she will get a 20% discount and the new member a 10%

discount. This new customer could get an additional 10% discount (that means 20% in total) if

he/she sponsor another member.

14 http://www.golfcoursesguide.org/europe/

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The “Ambassador” promotion

An exceptional promotion will be inviting a well-known star to our center in order to attract the

media’s attention. He/she won’t be paid but will benefit of our services for free.

3. Website

Elixir’s website will be organized in 4 different parts:

- Corporate: company’s presentation (about us, location, financial information, etc);

- Booking: online booking system;

- Forum;

- Personal account for patients (doctor’s contact, access to personal data, etc).

Our other ideas for the future are ads in some private clubs, private health center, brand shops,

cruise lounge, conferences concerning genetics, gala, ceremonies, festivals, fashion shows,

company (salon)…

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D. Place

The choice of the location was the result of a holistic thinking approach.

Austria enjoys close proximity to the growth markets of Central and Eastern Europe. In the last

years, this country remarked itself as a pole of competencies and research especially in new

medical technologies and products. Moreover, Vienna region developed into a dynamic

business location, with major players in pharmaceuticals and medical technology and a roster

of innovative new ventures.

With a rate of corporate income tax of 25%, Austria

has one of the lowest rates of business taxation in the

EU. In addition to this, there are generous deductions

and exemptions for investments in research and

education. R&D allowances of up to 25% (in special

cases up to 35%) are available on research and

development expenditure. Highly innovative

companies not making profits can claim a cash

premium of up to 8% of their research costs.

Moreover, according to Richard Blis survey of current

office rentals in 2007, location cost in Austria is one of

the cheapest among major European countries (see

figure 5)

For these reasons, numerous international corporations are already present in Austria, such as

Baxter - the world's largest research and competence centre for the development of state-of-the

art scanning technologies for blood products, Eli Lilly - responsible for planning, coordination

and implementation of clinical projects for diabetes, bone diseases, cardiovascular illnesses and

diseases of the central nervous system, or Novartis/Sandoz - one of the largest organizations in

Austria engaged in research.

Moreover, Life Science Austria (LSA) - Innsbruck region plays an important role as a first

point of contact and offers support and advice on potential start-ups, new arrival and businesses

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generally. It provides consultancy services, preparation of business plans, and financing. It

offers assistance in applying to national and regional funding programs and helps open up

access to private financing.

All these reasons, plus the beautiful nature and landscapes of Austria and especially Innsbruck,

lead Elixir to implement its first Health Cure Centre in Innsbruck’s suburb.

Concerning the offering of our services, since Elixir has mainly the role of an intermediary, our

customers will receive few of our services in the Elixir Health Care Center and most of them in

our registered partners.

� Location - Innsbruck

The Elixir Center is located in the suburb of Innsbruck which is the capital city of the federal

state of Tyrol in western Austria. It is located in the Inn Valley at the junction with the Wipptal

(Sill River), which provides access to the Brenner Pass, some 30 km south of Innsbruck.

Located in the broad valley between high mountains, the Nordkette (Hafelekar, 2,334 m) in the

north, Patscherkofel (2,246 m) and Serles (2,718 m) in the south, it is an internationally

renowned winter sports centre, and hosted the 1964 and 1976 Winter Olympics. The word

bruck comes from the German word Brücke meaning "bridge" which leads to "the bridge over

the Inn".

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� The Center

The Elixir Health Care Center is located at Katzenbründlweg 2, in the nature, surrounded by

mountains and trees, however with a good access, at only 20 minutes from downtown.

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The Elixir Health Care Center is a building of 3 stages with a total amount of 600 m² including:

Elixir

600 m² of premises1 conference room1 bar 7 roomsParkingCosts: 79200 € (+19800 € guarantee)cleaning: 36500 per yearSolar energy panels: 30 m² 33.000 €Deco: 20.000

- a welcome room - 2 doctor cabinets

- 2 psychologist cabinets - 2 multi-purpose rooms

- a research center for RFID technology - 2 wifi connected rooms

- 2 relaxation rooms for massage and hamam - 2 seminar rooms

� Access & transports

Innsbruck Hauptbahnhof , the most important railway station of Innsbruck and Tyrol, is one

of the most frequented railway stations in Austria. The Austrian east-west railway crosses the

south-west route through the Brenner pass, connecting northern Italy and southern Germany.

From the Railway station, the route to the Center is about 8.2 km which corresponds

approximately to 20 minutes by car.

Innsbruck Airport provides services including Frankfurt, London, and Vienna. There is 9.1 km

between the airport and the Center, which is approximately 25 minutes by car.

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Highway: Innsbruck is located along the A12/A13 corridor, providing freeway access to

Verona, Italy and Munich, Germany. The A12 and A13 converge near Innsbruck, at which

point the A13 terminates. The distance from the exit of the highway to the Center is 8.5 km

that is approximately 25 minutes by car.

The town's meter gauge tram-network consists of two city-lines and two lines serving the

surrounding area — the Innsbrucker Mittelgebirgsbahn to Igls and the Stubaitalbahn into the

Stubaital until Fulpmes. The network will be enlarged during the coming years to reach Hall in

Tirol in the east and Völs in the west. The trolleybus service will be abandoned as the tram

network is enlarged. Numerous bus lines serve the inner city and transport to surrounding

areas. At the end of 2007, the Hungerburgbahn — a funicular service to the district of

Hungerburg — has been inaugurated.

(For all the access maps see figure 6)

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E. Process

FIRST CONTACT

1. The customer contacts the center and asks for a DNA analysis.

2. Our center proposes him a DNA analysis starting from a sample of hair, skin, blood,

etc. The patient chooses the type of sample that he want to send, and makes an

appointment to come to our center. We will indicate him the nearest pharmacy where

he may buy the test kit or we will propose him to send it from our center.

3. To have the analysis results from the Medical University Innsbruck, it will take

approximately 3 weeks. During this time the client has 2 choices: first, he may come to

our center only when the results will be ready. Secondly, he may choose to earn some

time and to come earlier to our center in order for our specialists to already create his

family history and life style map.

« FIRST DAYS PACK »

It represents a three days welcome pack.

4. Thanks to our partnerships with Hotel Hilton Innsbruck and Schwarzer Adler Romantik

Hotel Innsbruck, our clients will fell our presence from the first contact with Innsbruck.

The hotels’ transfer cars will be at their service not only for the regular airport transfer

but also in order to bring them to our center.

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5. The first appointment will consist in mapping the family history and the life style of our

clients. This information along with the DNA test results will represent the basis of the

next steps in our process.

6. The patient will fell free to discover the city of Innsbruck or the entire region as a

tourist in order to combine the health care process with the pleasure of discovering a

part of Austria. He may benefit from the little relaxing activities which will take place

inside our center such as massage, hammam or seminars on the importance of the DNA

analysis today, tips about traditional Chinese preventive medicine, environmental

factors which influence our genetic heritage. In this way, our customer may make

himself an idea about the packs that we intend to present him after the analysis.

7. Meanwhile, the results will be already interpreted by our specialists and a personalized

pack will be ready to be proposed to our client.

8. Our intention is to make all the “First Days Pack” clients permanent clients of our

center, but the patients will also have the possibility not to go further in the preventive

process, at least not at that moment. As a consequence, we engage ourselves to keep the

information on their genetic map for a period of 10 years in order to facilitate an

eventual return of the clients to our center.

“FIT TO YOUR GENES STEP”

9. Once the client decides to adopt the preventive attitude and to “fight against his

destiny”, we present to him the options that fit the best the results of his DNA, family

history and lifestyle analysis. He will therefore have a large number of choices which

will all be in prevention optics (see the part “Products”). Three spa around Innsbruck:

Interalpen-Hotel Tyrol, AlpenMedHotel Lamm, Alpenresort Schwarz, two fitness

clubs: Holmes Place Health & Fitness Clubs, Fitness First, and Hotel Hilton’s

restaurants will be at the disposal the customer.

10. All these clients will receive a RFID bracelet or watch develop with HP and Cartier.

This will allow us to have a close follow up of our patients in order to permanently be

able to respond appropriately to their needs. This technical device will have several

other functions as listed in the part “Bracelet” of the present marketing plan.

11. Periodical check-ups will allow us to up date the medical record of our clients and, in

the same time, to measure the performance of our treatments.

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To resume, the customer will follow the following process:

For a complete list of our partners and the process on which they interfere see Figure 7 in

appendix.

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F. Risks Assessment

After a risk assessment study, four main risks were identified as being the main potential

sources of threats for Elixir. They are as follows:

1. Ethics

An important debate was launched from the very first DNA analysis concerning the use of the

highly confidential information identified during these types of tests15. Many questions seem to

be left without an answer in this delicate problem.

Intellectual Property and privacy: may genetic data be used for curative purpose of other

people?

- Regulation of genetic tests: The law is another problematic aspect when talking about the

ethics of a genetic mapping test. There is no unique legislation or international code of ethics

for genetics.

- The economic side of the genomic medicine: The following questions are raised: What will

be financial costs and societal benefits of integration of genomics into health care? Will society

ultimately save money through increased productivity of a healthier population? How can we

ensure that all benefit from genomic medicine and that it is not exclusive?

- Re-evaluation of the health care system: Most health care professionals have insufficient

knowledge about genomic medicine and there are too few geneticists and genetic counselors.

Therefore, how should the current health care system should be adapted to the genomic

medicine?

- Genetic non-discrimination: There is no legislation that prevents genetic discrimination by

employers and health insurance providers. Employers may seek to use genetic testing to

identify someone who could turn out to be less productive or a strain on the company health

plan. Insurance companies may refuse clients found to be at high risk of certain conditions.

15 http://www.genome.gov/17516574

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- Reimbursement by health insurers: Nowadays, there is no health insurance reimbursement for

genetic services.

- RFID: see appendix

2. Financial risks

Our main financial risk is that the technology used and our preventive treatment could be very

expensive. We will need a minimum of 1000 clients in order to cover in a first 30% of our

start-up costs (see finance tables). Therefore, the promotion of this new concept of preventive

medicine will play a very important role and it will be based on specific targets and complete

explanations of the services that we propose. As a consequence, we aim at a relatively rapid

and constantly increasing return on our investment.

Linked to this first risk, the implementation or the RFID technology may create cost concerns

to our partners as well. They may be at first reluctant to this kind of investment because of its

cost. We have therefore to prove them that this technology may lead to return on investment.

3. Technological risks

Innovating technologies can be used by our competitors. Elixir has therefore to elaborate a

business intelligence strategy in order to stay technologically ahead.

Medical Research and Development

We may assume that one day one day, a treatment will be found for curing diseases linked to

DNA. For example, an attempt has already made create an Alzheimer vaccination. If this

happens, we will have to develop new strategies in order to keep our customers.

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G. Future

1. Expanding Elixir’s business

Elixir aims to increase its number of customer by 48% in 10 years time. We predict a potential

market size of 1500 customers in 10 years time in Europe. In order to respond to this demand,

Elixir would create a new site on another European country. Spain, according to several

criteria, is a potential country we could build our next Elixir center.

Spain is well located to welcome customers from Portugal, France, Italy, Andorra (tax heaven

country), Gibraltar, the Maghreb countries and of course Spain, which could have been reticent

to our services because of the distance which separate them from the first Elixir center in

Innsbruck. The construction of a new site there could interest and attract new customers. Spain

has also an ideal climate and the sea, which differentiate it from Austria. We could then

develop new services using these specific features (geographical strengths). Moreover, Spanish

are more and more preoccupied by their health and have lot of interest concerning prevention.

Another point we could emphasis according to the NATO studies, is that in our potential

interested countries, the inequality of revenues are high (see Figure 8 – Gini Index). Also, with

741 hospitals and the pharmaceutical industry ranked 7th in the world and 5th in Europe, Spain

is a well equipped country in medical infrastructure.

The growing private healthcare industry is an interesting point too. Above the 741 hospitals,

442 are private ones. The private industry which is realizing 22% of the total treatment and hire

50000 physicians, showed a 2.7% growth in 2006. This growing interest for private industry

could be seen as a threat for us because of the high competition on the market, but on the other

hand, it could be seen as an opportunity because it means that there is a large potential that we

could exploit.

Also, we keep on improving our service by our research and development section.

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2. Future Technologies16

Although medical Research is one of Elixir’s main concerns, we believe that technology too

has an influence on medicine practice. More important than surgery and drugs, technologies

can revolutionize the medical profession.

More than only implementing RFID, Elixir will also do Research and Development in order to

use the newest technologies, such as Telemedicine.

Telemedicine & E-Health17

Telemedicine is a rapidly developing application “ where medical information is transferred via

telephone, the Internet or other networks for the purpose of consulting, and sometimes remote

medical procedures or examinations” 18.

This technology is used in innovative health centers. Linked services such as internet websites

and magazines already exist to advise both patients and customers in treatment with this

technology. It will be an added value for Elixir.

Telemedicine will aim to:

- Easily keep in touch with our patients easily and partners (internet).

- Democratize our services. Technology usually lowers the barrier for the sale of goods and

services. Therefore, our center and doctors would most likely be able to more easily and

effectively treat a larger group and offer cheaper treatments.

- Implement a less bureaucratic medicine. New technologies will enable doctors to delivery of

vital medicine without bureaucratic delays or unnecessary paperwork.

16 http://www.fortherecordmag.com/archives/ftr_052305p22.shtml 17 http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=dcp2.section.632 18 http://en.wikipedia.org/wiki/Telemedicine

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Finance

A. Costs

1. Fixed Costs

- Personnel Charges

Maylis 70.000

Livia 60.000

Salman 45.000

Xing 45.000

Pauline 40.000

Diana 40.000

Alexandre 40.000

Noé 38.000

Hostess (x3) 60.000

438.000€

- Rent (infrastructures, leasing equipment...)

Wage 79.200

Guarantee 19.800

Cleaning (per year) 36.500

Solar energy panels: 30 m² 33.000

Decorating equipment 20.000

188.500

- Technology:

11 laptops 5.500

1 server 8.000

7 pc 3.500

Wifi 3.000

Phones 1.000

Other (wire, software, etc…): 1.500

22.500

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- Marketing Costs

Offline promotion:

Posters:

Design & print: 6.000

Diffusion in Airports: 4.000

Diffusion in Golf club: 3.200

Diffusion through partners: 0

Brochures:

Design &print (3000brochures, 0.5euros/brochure) 1.500

Diffusion: 500

Public relations:

Sponsorship system: (20customers, 2000euros) 40.000

The “Ambassador” promotion: 10.000

Online promotion:

Website

Website creation: 6.000

Maintenance: 4.000

Extra Communication agency fee: 10.000

85.200€

�As we rent the premises we have no provision for depreciation

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2. Variable Costs

- External Charges

Cost per Unit

Pessimistic

(632)

Average

(1012)

Optimistic

(1500)

Bracelet 1.000 632.000 910.800 1.275.000

Spa 2.000 1.264.000 1.821.600 1.574.000

Complementary

tests 800 505.600 728.640 1.020.000

DNA analysis 300 189.600 273.240 382.500

Hotels 1.500 948.000 1.366.200 1.912.500

3.539.200 5.100.480 6.164.000

� For each unit, cost per unit decreases as the number of customers increases (economies of

scales)

B. Scenarios

Pessimistic Average Optimistic

Total fixed costs 734.200€ 734.200 734.200

Total variable costs 3.539.200 5.100.480 6.164.000

Total costs 4.273.400€ 5.834.680€ 6.898.200€

Per client 6.762€ 5.765€ 4.599€

Price paid per customer 7.000€ 6.500€ 6.500€

Profit per customer 238€ 735€ 1.901€

Overall profit (1) 150.600€ 743.320€ 2.851.800€

Retained Earnings 100000 400.000€ 2.000.000€

Total profit (2) 50.600€ 343.320€ 851.800€

� 3 scenarios: pessimistic, average and optimistic

� Total profit (2) represents the profit, depending on the scenarios (after taking out the

charges per customer and retained earnings)

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3. Return on Investment

Scenarios Pessimistic Average Optimistic

Return on Investment (%) 1,01% 6,87% 17,04%

� The return on investment will be positive for the investor in the 3 scenarios.

4. Return on Investment – Long term

Scenarios Pessimist Average Optimistic

Initial investment 5.000.000 5.000.000 5.000.000

Y1 5.060.000 34.332.000 85.180.000

Y5 5.120.720 235.737.245 1.451.126.480

Y8 5.182.169 1.618.666.218 24.721.390.713

Extra: Media Plan

Media Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

Print 3000 2000 500 500 500 500 200

Radio 500 300 200

TV 4000 500 500 500 500 500 500

Public

Relations/

Publicity

30000 20000

Online 5000 500 500 500 500 500 500 500 500 500 250 250

� Most costs occur at the launch of the activity (Jan)

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Appendix

� Figure 1: Some Currently Available DNA-Based Gene Tests

• Alpha-1-antitrypsin deficiency (AAT; emphysema and liver disease) • Amyotrophic lateral sclerosis (ALS; Lou Gehrig's Disease; progressive motor function loss

leading to paralysis and death) • Alzheimer's disease* (APOE; late-onset variety of senile dementia) • Ataxia telangiectasia (AT; progressive brain disorder resulting in loss of muscle control and

cancers) • Gaucher disease (GD; enlarged liver and spleen, bone degeneration) • Inherited breast and ovarian cancer* (BRCA 1 and 2; early-onset tumors of breasts and

ovaries) • Hereditary nonpolyposis colon cancer* (CA; early-onset tumors of colon and sometimes

other organs) • Charcot-Marie-Tooth (CMT; loss of feeling in ends of limbs) • Congenital adrenal hyperplasia (CAH; hormone deficiency; ambiguous genitalia and male

pseudohermaphroditism) • Cystic fibrosis (CF; disease of lung and pancreas resulting in thick mucous accumulations

and chronic infections) • Duchenne muscular dystrophy/Becker muscular dystrophy (DMD; severe to mild muscle

wasting, deterioration, weakness) • Dystonia (DYT; muscle rigidity, repetitive twisting movements) • Emanuel Syndrome (severe mental retardation, abnormal development of the head, heart and

kidney problems) • Factor V-Leiden (FVL; blood-clotting disorder) • Fragile X syndrome (FRAX; leading cause of inherited mental retardation) • Galactosemia (GALT; metabolic disorder affects ability to metabolize galactose) • Hemophilia A and B (HEMA and HEMB; bleeding disorders) • Hereditary Hemochromatosis (HFE; excess iron storage disorder) • Marfan Syndrome (FBN1; connective tissue disorder; tissues of ligaments, blood vessel

walls, cartilage, heart valves and other structures abnormally weak) • Mucopolysaccharidosis (MPS; deficiency of enzymes needed to break down long chain

sugars called glycosaminoglycans; corneal clouding, joint stiffness, heart disease, mental retardation)

• Myotonic dystrophy (MD; progressive muscle weakness; most common form of adult muscular dystrophy)

• Neurofibromatosis type 1 (NF1; multiple benign nervous system tumors that can be disfiguring; cancers)

• Phenylketonuria (PKU; progressive mental retardation due to missing enzyme; correctable by diet)

• Polycystic Kidney Disease (PKD1, PKD2; cysts in the kidneys and other organs) • Adult Polycystic Kidney Disease (APKD; kidney failure and liver disease) • Sickle cell disease (SS; blood cell disorder; chronic pain and infections) • Spinocerebellar ataxia, type 1 (SCA1; involuntary muscle movements, reflex disorders,

explosive speech) • Spinal muscular atrophy (SMA; severe, usually lethal progressive muscle-wasting disorder

in children) • Thalassemias (THAL; anemias - reduced red blood cell levels) • Timothy Syndrome (CACNA1C; characterized by severe cardiac arrhythmia, webbing of the

fingers and toes called syndactyly, autism)

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� Figure 2: Example of the test procedure

- Epithelial cells of the oral cavity are collected by rubbing inside the patient's mouth with

sterile swabs. The samples are forwarded to our partner DNA lab in Vienna, where it is

analysed for polymorphisms

- The lab results are interpreted in combination with anamestic data provided by experts

working on the case

- The genetic testing, taken together with the patient's medical history, current diagnostic

procedures and outcome of counselling, leads to the charting of individual therapy and

prevention concepts for the patient.

Source: “gulf news”, 2003 article

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� Figure 3: Market Study

A) SWOT + PEST Table 1: Low rate unemployment: 4.2% in 2006

Table 2: One the lowest rate inflation among OECD

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Table 3: High expenditure on R&D, Austria is always finding new solutions and innovations

Table 4: 28% of GDP, superior to the European average: Austria, one of the richest country in the EU

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Table 5: Health expenditure as a percentage of GDP, OECD countries, 2006

Table 6: Health expenditure par capita, public and private expenditure, OECD countries, 2006

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Table 7: Austria endowment in health care system

Indicator Value (year)

Dentistry personnel density (per 10 000 population) 5.00 (2006)

Number of dentistry personnel 4,467 (2006)

Number of nursing and midwifery personnel 53,782 (2006)

Number of Pharmaceutical personnel 5,076 (2005)

Number of Physicians 30,068 (2006)

Nursing and midwifery personnel density (per 10 000 population) 66.00 (2006)

Pharmaceutical personnel density (per 10 000 population) 6.00 (2005)

Physicians density (per 10 000 population) 37.00 (2006)

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Table 8: Leading causes of death (ICD-10), age standardized per 100 000 inhabitants, 1970-2004

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Table 8 – Examples of competitors

The Germany's Fresenius Group, who builds and participates in the management of

hospitals such as Vienna's General Hospital and the Trauma Hospital in Linz, as well as

health resorts, senior centers and thermal spas including Oberlaa, Laengenfeld and Geinberg.

One of its newest projects is the thermal spa Laa an der Thaya, which will be expanded by

2008 to include a health and wellness academy as well as a center of competence at the

polytechnic university level and a 30-to-40 million euro four-star hotel. An additional area of

activity is to develop projects in health-related tourism, including the current "Aqua Dome"

thermal spa project in the Tyrolean Oetz Valley, which will open in 2004 and in which

VAMED is an investor. VAMED is also a player in the ongoing wave of hospital

privatizations.

The private hospital company Helios, based in Fulda, Germany, specializes in the operation

of acute care clinics, employing around 13,000 workers in 22 clinics in Germany and Austria.

The Kitzbuehel Hospital in Tyrol was acquired by Helios in June 2001, and is up to now its

only foreign subsidiary, employing around 220 workers in the hospital and a nursing home.

The hospital was renovated in eight phases and equipped with radiological and sleep

laboratories. Helios has invested 3.5 million euros in the facility to date and plans additional

expenditures of around one million euros.

Table 9 – Country Risk

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Table 10 – World Competitiveness Yearbook 2007

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B) Open market

Table 11 – Cancer Incidence

Table 12 – Daily smokers statistics

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� Figure 4: More information about the RFID technology

Passive RFID tag

Passive RFID tags have no internal power supply. The minute electrical current induced in the antenna by the incoming radio frequency signal provides just enough power for the CMOS integrated circuit in the tag to power up and transmit a response. Most passive tags signal by backscattering the carrier wave from the reader. This means that the antenna has to be designed both to collect power from the incoming signal and also to transmit the outbound backscatter signal. The response of a passive RFID tag is not necessarily just an ID number; the tag chip can contain non-volatile data, possibly writable EEPROM for storing data.

Passive tags have practical read distances ranging from about 11 cm (4 in) with near-field (ISO 14443), up to approximately 10 meters (33 feet) with far-field (ISO 18000-6) and can reach up to 600 feet (183 meters) when combined with a phased array. Basically, the reading and writing depend on the chosen radio frequency and the antenna design/size. Due to their simplicity in design they are also suitable for manufacture with a printing process for the antennas. The lack of an onboard power supply means that the device can be quite small: commercially available products exist that can be embedded in a sticker, or under the skin in the case of low frequency (LowFID) RFID tags.

Issues of RFID technology (in french)

L’usage du RFID pour l’identification des individus encore problématique

Un rapport encore au stade d’examen au Département of Homeland Security (DHS) vient contrarier le consensus apparemment partage entre industriels et le DHS selon lequel la technologie d’identification par fréquences radio RFID serait la voie à suivre pour l’identification et le suivi des individus. Alors que le Département d’Etat a déjà commence a diffuser des passeports munis de puces RFID et prévoit de diffuser des cartes aux visiteurs du Mexique, du Canada et des Bermudes munies de puces RFID lisibles a 6 mètres et que l’usage de RFID soit prévu pour les cartes d’authentification dont tous les employés fédéraux doivent être munis, ce rapport souligne les failles a la fois au niveau de la confidentialité et de la sécurité que poserait l’usage de RFID. Il rejoindrait en ce sens l’avis de nombreuses associations de défense de la vie privée. Par ailleurs, ce rapport corrige certaines idées reçues. D’abord RFID n’accélère pas le traitement de l’identification d’un individu puisque la technologie est juste un moyen de transmettre des données, elle n’assure pas seule l’identification : une autre opération doit être effectuée, comme une authentification biométrique, plus lente. Ensuite la sécurité contre la falsification apportée par l’usage de la cryptographie n’est pas propre a RFID mais peut être apportée par de simples données imprimées. En l’état, il déconseille l’usage de RFID pour l’identification et le suivi d’individus. Le rapport est disponible sur le site web du DHS mais certains craignent qu’il ne soit jamais valide car gênant pour les industriels et ceux qui se sont déjà lance dans l’adoption de la technologie. Le porte-parole du DHS a nie toute volonté au sein du DHS de tuer le rapport : il serait en cours d’examen.

http://asso.objectif-sciences.com/L-usage-du-RFID-pour-l.html?decoupe_recherche=rfid http://www.dhs.gov/xlibrary/assets/privacy/privacy_advcom_rpt_rfid_draft.pdf

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� Figure 5: Office rental cost in Austria

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� Figure 6: Getting to the Center - Access & transports

Innsbruck Hauptbahnhof , the most important railway station of Innsbruck and Tyrol, is one of the most frequented railway stations in Austria. The Austrian east-west railway crosses the south-west route through the Brenner pass, connecting northern Italy and southern Germany. From the Railway station, the route to the Center is about 8.2 km which corresponds approximatly to 20 minutes by car.

Innsbruck Airport provides services including Frankfurt, London, and Vienna. There is 9.1 km between the airport and the Center, that is approximately 25 minutes by car.

Highway: Innsbruck is located along the A12/A13 corridor, providing freeway access to Verona, Italy and Munich, Germany. The A12 and A13 converge near Innsbruck, at which point the A13 terminates. The distance from the exit of the highway to the Center is 8.5 km that is approximatly 25 minutes by car.

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The town's metre gauge tram-network consists of two city-lines and two lines serving the surrounding area — the Innsbrucker Mittelgebirgsbahn to Igls and the Stubaitalbahn into the Stubaital until Fulpmes. The network will be enlarged during the coming years to reach Hall in Tirol in the east and Völs in the west. The trolleybus service will be abandoned as the tram network is enlarged. Numerous bus lines serve the inner city and transport to surrounding areas. At the end of 2007, the Hungerburgbahn — a funicular service to the district of Hungerburg — has been inaugurated.

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� Figure 7: Our partners

• Before coming to Elixir Health Care Center

DNA analysis:

- Medical University Innsbruck

• “FIRST DAYS PACK” – Services in Innsbruck Hotels:

- Schwarzer Adler Romantik Hotel Innsbruck - Hotel Hilton Innsbruck

Restaurants: - Hotel Hilton Innsbruck: Guggeryllis Restaurant - Schwarzer Adler Romantik Hotel Innsbruck’s restaurant

Sport centers:

- Hotel Hilton Innsbruck - INJOY International Sports

• “FIT TO YOUR GENES STEP” – Services outside Innsbruck Restaurants: Hotel Hilton’s restaurants Austria

- Hotel Hilton Vienna Danube: Symphony Restaurant - Hotel Hilton Vienna: S’PARKS Restaurant - Hotel Hilton Vienna Plaza: Plaza Restaurant

Germany - Hotel Hilton Munich City: Lowenschanke Restaurant - Hotel Hilton Munich Park: Tivoli Restaurant

Italy - Hotel Hilton Milan: Pacific Milano Restaurant - Hotel Hilton Molino Stucky Venice: Aromi Restaurant

Switzerland - Hotel Hilton Bazel: Wettstein Restaurant - Hotel Hilton Zurich Airport: Market Place restaurant

Sport centers: Holmes Place Health & Fitness Clubs and Fitness First (for Italy only) Austria

- Holmes Place Health & Fitness Clubs Linz - Holmes Place Health & Fitness Clubs Salzburg - Holmes Place Health & Fitness Clubs Vienna

Germany - Holmes Place Health & Fitness Clubs Berlin - Holmes Place Health & Fitness Clubs Düsseldorf - Holmes Place Health & Fitness Clubs Hamburg - Holmes Place Health & Fitness Clubs Köln

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- Holmes Place Health & Fitness Clubs Lübeck Italy

- Fitness First Milano - Fitness First Parma - Fitness First Torino - Fitness First Verona

Switzerland - Holmes Place Health & Fitness Clubs Geneva - Holmes Place Health & Fitness Clubs Lausanne - Holmes Place Health & Fitness Clubs Oberrieden - Holmes Place Health & Fitness Clubs Zurich

Spa: Austria

- Interalpen-Hotel Tyrol - AlpenMedHotel Lamm - Alpenresort Schwarz

• The “Bracelet/Watch” RFID tag:

- HP Bracelet/Watch design:

- Cartier

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� Figure 8: The Gini Index

The Gini index

The Gini index demonstrates inequalitities in revenue per country.

Portugal 0.385 (deciles 15 – quartiles 8.0 - 1997)

France 0.327 (deciles 9.1 – quartiles 5.6 - 1995)

Italia 0.36 (deciles 11.6 – quartiles 6.5 - 2000)

Andorre

Tunisia 0.398 (deciles 13.4 – quartiles 7.9 - 2000)

Morocco 0.395

Algeria 0.353

by NATO 2005

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References http://www.ornl.gov/sci/techresources/Human_Genome/medicine/genetest.shtml

http://en.wikipedia.org/wiki/Genetic_testing

http://www.genosense.at/EN/Patienteninfo.html

http://www.lifesciencesdirectory.at/index.php?file=search.php

http://www.lifesciencesdirectory.at/index.php?file=show.php&ref=117

http://books.google.fr/books?hl=fr&id=0pHihB78KrUC&dq=chinese+medicine+cardiovascular+dise

ases&printsec=frontcover&source=web&ots=At4qiWwB-T&sig=-

S6nqmR3ICviFTBf6dt3CIjRKJs&sa=X&oi=book_result&resnum=5&ct=result#PPA58,M1)