master of science in medical and clinical...

FFaaccuullttyy ooff MMeeddiicciinnee AAiinn SShhaammss UUnniivveerrssiittyy

PPoossttggrraadduuaattee SSttuuddiieess

Master of Science in Medical and Clinical

Genetics

اإلكلينيكية و درجة الماجستير في الوراثة الطبية

PPrrooggrraamm CCooddee::

Program Guide and

Logbook

3

C a n d i d a t e C u r r i c u l u m v i t a e

[Name]

Please attach

your recent

photo

[telephone no]

[mobile no]

[mailing address]

[email address]

[postcode]

Experience

[organization]

[your present job title]

[start date]

[location]

[responsibilities]

[organization]

[previous job title]

[start and end date]

[location]

[responsibilities]

[organization]

4

[previous job title]


[location]

[responsibilities]

Education

[certificates]


[school or college]

5

Training

[any other training that will be useful in your job]

Filled by post graduate authorities

Date of Registration

First semester _______________________

Second semester _______________________

Third semester _______________________

Fourth semester _______________________

6

TABLE OF CONTENTS:

I – Welcome Statement

II - Mission Statement

III – Senior supervisor and affiliated departments and Hospitals

IV – Program specifications

1 - Basic Information

2 - Professional Information

3 - Academic standards

4 - Curriculum structure and contents

5 – Program courses

6. Program admission requirements

7. Regulation for progression and program completion

8. Appendix of program: course specifications

First part

1. Physiology

2. Biochemistry and biochemical genetics

3. Pharmacology and pharmacogenetics

4. Microbiology & immunology

5. Parasitology

6. Embryology

7. Public Health, Preventive, basics of nutrition, and Statistics

Second part

8. Medical genetics

Elective courses

9. Molecular biology

10. Medical statistics

V - General information

VI – Your log book

1 – Introduction

2 - Supervisors, Trainers and/or Educators

3 - Tables for training records

4 – Log book preview

VII - Head of department approval for the exam entry

Detachable forms:

VIII – Thesis follow up

IX - Evaluation forms

7

I – WELCOME STATEMENT:

The Department of Pediatrics welcomes you to the Master of Science in

Medical and clinical Genetics. As a department we are committed to medical

student education and continuously strive to improve your educational experience.

This handbook presents information guide and logbook activity of this degree

administered by the Pediatric department, Faculty of Medicine, Ain Shams

University

II - MISSION STATEMENT:

The mission of the Faculty of Medicine, Ain Shams University is

“Preparation of a trained physician, researcher and lifelong tutor capable of

following standards of medical care and ethics, with managerial and technical

skills in his specialty. Furthermore, promotion outstanding programs of health

care to serve the society, environmental development and targeted scientific

research for continual improvement of health”.

The mission of this degree is providing the candidate with the principles

and applications of medical, clinical and community genetics, together with the

principles and practices of genetic counseling, and the interpretation of

laboratory genetic tests. At the end of the degree the individual will be a

competent medical and clinical geneticist. In addition, a research project is

carried out and is written. This provides the student with an introduction to

research methodology, protocol writing, ethics and grant applications.

III – SENIOR SUPERVISOR AND AFFILIATED DEPARTMENTS AND

HOSPITALS

SENIOR SUPERVISOR

Prof. Mohamed Saad Zaghloul Salem

E-mail: [email protected], [email protected]

AFFILIATED DEPARTMENTS AND HOSPITALS

Pediatric department, Faculty of Medicine, Ain Shams University

Genetics unit, Pediatric department, Faculty of Medicine, Ain Shams

University.

http://us-mg6.mail.yahoo.com/yab-fe/mu/MainView?.src=neo&themeName=img-flowers&bn=54_9364&s=0&isFresh=1&bucketId=0&stab=1378812547292

http://us-mg6.mail.yahoo.com/yab-fe/mu/MainView?.src=neo&themeName=img-flowers&bn=54_9364&s=0&isFresh=1&bucketId=0&stab=1378812547292

8

Physiology, Biochemistry, Pharmacology , Anatomy, Microbiology &

Bacteriology, Parasitology and Public Health departments, Faculty of Medicine,

Ain Shams University.

IV – PROGRAM SPECIFICATIONS

A- Basic Information

1. Program title: Master of Science in Medical and clinical Genetics

2. Program type: single

3. Faculty: Faculty of Medicine

4. Department of pediatrics.

5. Assistant coordinator: Dr. Solaf Mohamed

Coordinator:

Prof. Mohamed Saad Zaghloul

Prof. Solaf Mohamed Elsayed

Prof. Rabah Mohamed Shawky

Prof. Mohamed Abd-Eladl El-Sawi

Prof. Karam Abdelaleem

Prof. Ezzat Elsobky

6. Last date of program approval:

……………………………………………………………………………………….

B- Professional Information:

Program aims:

1- Overall aims of the course:

The aim of the Masters in Medical and Clinical Genetics is:

1- To facilitate the acquisition and integration of a knowledge base in all

areas of Medical and clinical Genetics that enable students to understand

inherited diseases and the diagnostic and screening methodologies which may

be employed to benefit individuals, families or populations.

2- To enable students to work with family information and diagnostic data in

order to provide genetic risk assessment and best genetic advice to individuals

and their families in an ethical way.

9

3- To provide students with the opportunity to work with a team of their

peers to investigate real clinical scenarios using their critical understanding of

Medical and clinical Genetics to suggest appropriate diagnoses, investigations,

management and counseling .

4- To develop students’ skills in problem solving, literature searches,

scientific writing, oral presentations, and team working.

5- The program will also provide an opportunity and encouragement for

appropriate candidates to apply for a MD Degree in Medical and clinical

Genetics

2- Intended learning outcomes (ILOs):

a- Knowledge and understanding:

By the end of this course the student will be able to:

a1- know, recognize and identify the genetic perspective of:

1- Physiologic basis of genetics disorders.

2- Biochemical basis of genetics and biochemical genetics.

3- Pharmacogenetics.

4- Microbiologic basis of genetics disorders.

5- Embryology of the fetus and embryologic basis of various congenital

anomalies.

6- Role of public health and preventive medicine in genetics

7- Statistical methods, study designs, data collection and analysis

8- Parasitology basis of genetics disorders.

a2- Describe the molecular basis of different inherited disease and the molecular

diagnostic methods which are used to identify the causative mutations in patients

or carriers in order to provide suitable genetic information and prenatal diagnosis

where appropriate.

a3- Identify the chromosomal disorders and the cytogenetic and molecular

cytogenetic diagnostic methods which are used to characterize the underlying

chromosomal abnormality for the purposes of providing counseling and prenatal

diagnosis where appropriate.

a4- Describe treatments and therapy for inherited disease and cancer, including

novel therapies such as gene therapy.

a5- Outline the principles and practice of population screening programs for

ascertaining carrier status of inherited disease, identifying at-risk individuals

prenatally or following birth, and for prenatal identification of pregnancies at risk

of chromosomal disorders or congenital defects.

10

a6- Recognize the principles and practice of non-directive genetic counseling

relating to reproductive choices, pre-symptomatic, diagnostic, carrier and prenatal

testing for families affected by genetic disorders.

a7- Know the ethical issues which are an inherent part of Medical Genetics.

b- Intellectual skills:

By the end of this course the student should be able to:

b1. Deal with complex clinical scenarios and develop original and creative

responses and select appropriate laboratory tests.

b2. Apply problem solving skills and intellectual independence to individual

clinical situations.

c- Professional and practical skills

By the end of this course the student should be able to:

c1. Use their knowledge in Medical Genetics and clues from pedigree, family

history and other information to suggest likely inheritance patterns and / or

diagnoses.

c2. Use of online molecular, genetics and dysmorphology databases to assist

with acquisition of relevant data and selection of possible diagnoses.

c3. Select the diagnostic or screening methods which will be most appropriate

and informative in a given clinical situation whilst taking into account the wishes

of patients.

c4. Identify appropriate information to be given to patients and their families,

including more far-reaching issues which might not have been identified by

patients or their referring clinicians.

d- General and Transferable/key skills

By the end of this course the student should be able to

d1. Work safely in a laboratory environment.

d2. Be responsible for one’s own work in independent tasks and as part of a

team effort.

d3. Have an effective time management skills to accomplish individual

designated tasks by a given date.

d4. Develop a team leadership.

d5. Use of online databases and e-journals;

11

3. Academic standards: (Benchmarks)

Academic reference standards (ARS) of NAQAAE guided by:

1- University of: Glasgow: Website: http://www.gla.ac.uk/

2- American college of medical genetics: www.acmg.net

3- Canadian college of medical genetics: www.ccmg-ccgm.org

4- British Joint Royal colleges of physicians training board.

4. Curriculum structure and contents:

4.1-Program duration: 2 years (4 semesters)

4.2 Program structure:

انمناهج

انكود انممرراث اندراست انساعاث

انمعتمدة

دورة أساساث انبحث انعهم متطهباث انكهت

اجضء األي

2 فبسبوج(-و١١بء د٠١خ –: )فغ١ج اجػخ األ -1

ػ –طف١١بد – بػخ اجػخ اثب١خ : )١ىشث١ج -2

ساثخ اخ١خ امغب اخ١خ( - ١خاألجخ ازشبد اخم 2

2 ادصبء( -رغز٠خ –طت لبئ –اجػخ اثبثخ )صذخ ػبخ -3

6 اشعبخ

ظش اساثخ اطج١خ اجضء اثب17

امشساد

االخز١بس٠خ

٠خزبس اطبت بدح ادذح

اج١ج١ب اجض٠ئ١خ -دسح ف االدصبء اطج 1

6 ألشطخ وشاعخ ا

63 انمجموع

http://www.gla.ac.uk/

http://www.acmg.net/

http://www.ccmg-ccgm.org/

12

5. Program courses:

5.1 Semester 1 -Compulsory: Basic Sciences

CODE

NO

COURSE TITLE CREDIT

HOURS

(LECTURE

HOURS)

PROGRAM

ILOS

COVERED

(BY NO.)

Physiology 0.7 10.5 a1

Biochemistry and biochemical

genetics

0.7 10.5 a2

Pharmacology and

pharmacogenetics

0.6 9 a3

Microbiology &Bacteriology 0.5 7.5 a4

Embryology 1 15 a8

Parasitology 0.5 7.5 a5

Public Health, &Preventive

Medicine

1 15 a6

Statistics 1 15 a7

L: Lecture, C: Clinical, lab: laboratory, SDL: Self directed learning

5.2 Semester 2, 3 and 4

a. Compulsory

CODE

NO.

COURSE

TITLE

MODULE NO. OF

CREDIT

HOURS

NO. OF HOURS PROGRAM

ILOS

COVERED

(BY NO.)

L. C. P SDL

Medical

Genetics

Module A 6 + a9, a10

Module B 6 + a10, a11,

a13

Module C 5 + a12, a14,

b1,b2, c3, c4

Total

L: Lecture, C: Clinical, and SDL: Self directed learning

Module A: Basic principles of genetics

Module B: Diagnostic, clinical and therapeutic genetics

Module C: Clinical and applied genetics

13

Students are required to attend all 3 modules to complete the program.

b. Elective courses – number required: 1

CODE COURSE TITLE NO. OF

CREDIT

HOURS

NO. OF HOURS

L C/lab SDL

Medical statistics 1 9 12

Molecular biology 1 9 12


Students are required to complete 1 elective course per program

6. Program admission requirements:

-( : شترط نمد انطانب نهحصول عهى درجت انماجستر:3) انمادة

ػ دسجخ ا - 1 جىبس٠ط ف اطت اجشادخ إدذ جبؼبد جس٠خ صش أ ٠ى دبصال

-4 افمخ جخ اؼ -3 أ ٠ى لذ أض عخ ازذس٠ت )االز١بص( -2 اؼشث١خ أ ػ دسجخ ؼبدخ

-5( 1رغذ٠ذ اشع صبس٠ف ازذس٠ت اعزالن األجضح اعز١فبء اغزذاد اطثخ ف اذك )

0ذح فص١ دساع١١ لج دخي ازذب اجضء اثب ازفشؽ ذساعخ

-ابجغز١ش األساق ازب١خ :خ ٠مذ طبت اإلزذبق ذسج ( :1مهحك )

الهف -5شهبدح اه١الد أ غهزخشس سعه -4شهبدح اإلز١هبص -3شبدح اجىبس٠ط -2طت إزذبق -1

-8صهس فررشاف١هخ جذ٠هذح 6ػهذد -7فهشؽ اطهة افمخ جخ اؼ ػه ازغهج١ از -6 0 ازج١ذ

ثبغجخ افذ٠ ٠مذ اطبت افمخ اغفبسح ٠ذذد جخ رذ افمبد وب ٠مذ شبدح صذ١خ

7. Regulation for progression and program completion

زه أخهش أرغهطظ ػه أ رجهذأ ٠ز ازغج١ بجغز١ش شح ادذح فه اغهخ رجهذأ ه أي ١٠ه د(: 8مادة )

٠جهص لجهي رغهج١ اهاة اؼ١هذ٠ اافهذ٠ فه افزهشح ه أي 0اذساعخ ف شش أوزثش وه ػهب

ههفجشدز أخههش د٠غههجش ػهه أال ٠غههخ هه ثههذخي إزذههب اجههضء األي إال ثؼههذ إمضههبء فزههشح اذساعههخ

.اطثخ

بؼ ػ فص١ دساع١١ ذح وه هب خغهخ ػشهش اعهجػب ا ٠جهذا رصع اذساعخ ف و ػب ج(: 9مادة )

االي ف أي أوزثش ٠جذا اثب ف صف فجشا٠شا غ رظ١ فص دساع ص١ف ىثف ذح عهزخ اعهبث١غ ا

٠هز ازغهج١ فصه اذساعه لجه اعهجػ١ ه ثذا٠زه ػه االله ثؼهذ إعهز١فبء اشهشط دغهت امههشساد

عهبػبد ؼزهذحا ٠جهص طبهت رؼهذ٠ 6ا ال٠جغ أ ٠ض٠ذ اؼتء اذساع ف افص اادذ ػه اغجخ

امشساد خالي اعجػ١ ثذا٠خ افص اذساع )ثبذزف ا االضبفخ(ا وب ٠جص االغذبة خالي عهز

اعبث١غ ادذ امشاسد د ادزغبث ساعجب ف١ا

عخ ذصي ػ ابجغز١ش أسثؼخ ػشش ششا )أسثؼخ فصي دساع١خ( : ذح اذسا( 11انمادة )

ػ جضئ١ ٠جزبص ف١ب اطبت ثشبجب رذس٠ج١ب زىبال طجمب غبػبد اؼزذح اضذخ ثبجبة اشاثغ

الثخ ال ٠غخ ثذخي اإلزذب لج إعز١فبء ثاألشطخ ٠غزف خالب اطة خ ف وز١ت زبثؼخ

0أسثبع اطة خ ف و جضء اجشبج

٠جزبص ثؼذب اطبت إزذبب ال ادذ ذح اذساعخ ف ابجغز١ش اجضء األي فص دساع ( :11انمادة )

زذس٠ت٠شزشط اجبح ف١ ثبىب إلزمبي ذساعخ ف اجضء اثبا اجضء اثب ٠زطت رفشؽ اطبت

اثأدذ اغزشف١بد أ اشاوض اؼزذح اى١خ دساع١١ذح فص١

14

٠م اذاسط ذسجخ ابجغز١ش ثزغج١ ضع اشعبخ ػ شى ثذث ظش أ ػ ثؼذ ( : 16مادة )

ػ األل ػ ازغج١ إعز١فبء فص دساع ادذ ػ األل ٠جص أ ٠بلش سعبزخ ثؼذ عزخ شس

مشساد اجضء األي ثبىب لج دخي إزذب اجضء اثب ال ٠خصص ب أ ٠ى لذ جخ ف

ث دسجب

٠م داسط ابجغز١ش ثإعز١فبء زطجبد اجبؼخ لج رغج١ اشعبخ زطجبد اى١خ لج ( : 11مادة )

اإلج١ض٠خ زطجبد اجبؼخ اذصي ػ شبدح از٠ف ف اغخ ادخي إزذب اجضء اثب

دسجخ ػ األل( زطجبد اى١خ دضس دساد ؼزذح جخ اذساعبد اؼ١ب 450ثجع )

اإلدصبء اطج أ ثإجز١بص إخزجبساد خبصخ رذذدب اجخا بج اجذث اؼثبى١خ ف جبي

ش ثزغج١ سعبخ ابجغز١ش خالي ٠جص ذبص١ ػ دسجخ اذث إعزىبي دسجخ ابجغز١(: 11مادة )

أسثغ عاد اذصي ػ دسجخ اذث ٠ذص ػ اذسجخ ثؼذ إعز١فبء زطجبد اجبؼخ اى١خ

بلشخ اشعبخ ثجبحا

اغبػبد اؼزذح ذساعخ ابجغز١ش ثالث عبػخ ؼزذح ػ األل ٠خصص ب عذ عبػبد (: 13مادة )

رش عذ عبػبد ػ األل جضء األي ثب ػششح عبػخ ػ األل جضء طخ زبثؼخ األشىز١ت

٠ضبف إ١ب عذ عبػبد شعبخ ف ابجغز١شا اثب

ذح ام١ذ ذسجخ ابجغز١ش أسثغ عادا(: 11مادة )

أليا دسجخ جضء ا 300دسجخ ب 1200جع دسجبد االزذب ابئ بجغز١ش (: 11مادة )

دسجخ بجغز١شا 300 ازشاو ثب ٠اص ص٠ضبف ا١ب اؼذي اف

٠ؼمذ إزذب اذس األي ف أوزثش فجش و ػب ٠ؼمذ إزذب اذس اثب ف أثش٠ (: 11مادة )

ب٠ و ػبا

اذسجخ اى١خ ى جب % ٠60ى اجبح ف و بدح ابجغز١ش ثؼذ اذصي ػ (: 13مادة )

% ٠60ى اجبح ف اد اذوزسا ثؼذ اذصي ػ % 50ػ اال ٠م ازذش٠ش ػ ابدح جزؼخ

ازذش٠ش اؼ االو١١ى اشف و ػ دذحا دسجخ

(: فهه دبههخ إعههزفبر ههذح ام١ههذ ٠ىهه طبههت اذساعههبد اؼ١ههب إػههبدح ازغههج١ ههشح أخههش ال ٠ؼزههذ 19)مااادة

األي أ اشعبخ ٠جت إػبدربا ثبجبح ف اجضء

Assessment Schedule and Weighing of Assessments

All course specifications should be included as appendices

ػ اج ازب:ذظخ: رؼبدي دسجبد اطبت طجمب مبط

نماط 1 : % فأكثر 99 -1 A

نماط 6633 : % 99% حتى ألم من 81من -1 A-

نماط 6666 : %81% حتى ألم من 89من - 6 B+

نماط 6699 : %89% حتى ألم من 31من - 1 B

نماط 1633 : %31% حتى ألم من 39من - 1 B-

نماط 1666 : %39% حتى ألم من 31من - 3 C+

نماط 1699 : %31% حتى ألم من 31من -3 C

نماط 1633 : %31% حتى ألم من 39من - 8 C-

F صفر : %39ألم من - 9

( ػه أعهبط جهع دبصه ضهشة مهبط وه مهشس ضهشثب فه ػهذد ٠GPAز دغبة اؼذي افص )

ذح مشساد از دسعهب اطبهت فه افصه اذساعها وهب ٠هز عبػبر اؼزذح مغب ػ اغبػبد اؼز

15

( ػه أعهبط جهع دبصه ضهشة امهبط ازه دصه ػ١هب CGPAاؼهذي ازشاوه طبهت ) دغبة

اطبت ف و مشس ضشثب ف ػذد عبػبر اؼزذح مغب ػ جع اغبػبد اؼزذح اى١خا

ابجغز١ش ٠هز اإلػهبدح فه اهبدح أ اجػهخ فمهظا ف مشساد ا جػخ ف دبخ اشعة ف بدح أ

٠ز دغبة ازمذ٠ش افؼ از ٠ذص ػ١ ف أي إػهبدح فمهظ أهب إرا رىهشس سعهثخ ف١ذغهت ه ػهذ اجهبح

مبط ا 67ا1% فمظ )ا60رمذ٠ش -

C)6

االمتحاناث انمناهج

انكود انممرراث اندراست ساعاث ان

انمعتمدة

مجموع اكهنك شفوي عمه تحرري

عدد اندرجاث

األوراق

اندرجت

متطهباث

انكهت

دورة أساساث انبحث

انعهم

اجضء

األي

اجػخ األ: -1

و١١بء –)فغ١ج

ث١ج١ب اساثخ د١

فبسبوج(-

2

1 80 20 300

ثب١خ : اجػخ ا -2

بػخ )١ىشث١ج

ػ األجخ –طف١١بد –

ساثخ - ازشبد اخم١خ

اخ١خ امغب اخ١خ(

2

1 80 20

اجػخ اثبثخ -3

طت لبئ –)صذخ ػبخ

ادصبء( -رغز٠خ –

2

1 80 20

6 اشعبخ

اجضء

اثب ظش اساثخ اطج١خ

17

1 150

130

150

30

30

360 850

امشساد

االخز١بس

٠خ

٠خزبس اطبت بدح ادذح

-دسح ف االدصبء اطج

اج١ج١ب اجض٠ئ١خ

1

1 50 50

وشاعخ

األشطخ

1200 360 120 720 63 انمجموع

لفصول الدراسية درجة في نهاية ا 011ملحوظة: يوجد تقييم دوري في نهاية كل فصل دراسي )

2-3-4)

16

FIRST PART COURSE SPECIFICATIONS

Physiology Course Specification University: Ain Shams University Faculty: of Medicine

Course specifications

Program on which the course is given: Master of science in Medical and clinical

Genetics Major or minor element of programs: Major

Department offering the program: Pediatric department (Genetics unit)

Department offering the course: Physiology department.

Academic Level: Master – 1st semester

Date of specification approval: …………………………..


Title: Physiology course Code:

Credit Hours: 0.7 hour Lecture: 0.7h/week Total: 10.5 hours

Coordinator

Physiology department

A. Professional Information

1. Course Aims:

By the end of this course the candidate will

1. Acquire an appropriate background on the physiology of cells, tissues,

organs and systems.

2. Integrate physiological data and mechanisms with the ongoing basic

sciences: anatomy, histology and biochemistry and clinical applications.

3. Explore in detail the functions of the autonomic, the neuromuscular, the

respiratory, cardiovascular, renal, endocrinal and gastrointestinal systems as

well as their integration to achieve homeostasis.

4. Develop the basic scientific research skills as well as effective

communication and team work attitudes.

2. Intended Learning Outcomes (ILOs) from the Course:

3.

a. Knowledge and understanding

By the end of the course the candidate will be able to:

17

a1 Recognize and describe basics of water, electrolyte and acid base balance

and their disturbances

a2 Describe the normal physiology of growth and deviations from normal

a3 Understand the basis of thermoregulation and energy balance

a4 Understand physiologic basis of endocrinal organs including calcium

homeostasis, thyroid gland and glucose metabolism

a5 Recognize the basics of cardiac and respiratory physiology

a6 Describe the physiologic basis of hematologic disorders including

hemostasis, anemias , WBCs and blood transfusion

a7 Understand physiologic basis of gastrointestinal tract, Liver and pancreas

a8 Recognize basis of renal physiology

a9 Recall the physiology of the spleen and reticuloendothelial system-

immune mechanisms and their disorders

a10 Understand Neonatal physiology (cardiovascular, respiratory, metabolic,

hematological, endocrinal, gastrointestinal, neurological changes and responses)

a11 Understand CNS physiology including Control of voluntary movements

and lesions, muscle state tone and its control, extrapyramidal physiology, nerve

and muscle physiology)

b. Intellectual skills


b1 Interpret the most important physiological laboratory results (blood,

cardiac, respiratory, urinary, gastrointestinal, hepatic, immunologic, endocrinal

and neuromuscular), to distinguish a physiological from a pathological

condition.

b2 Comment, on some clinical parameters such as: ABP, ECG, nerve

conduction velocity & pulmonary functions for a normal individual.

b3 Integrate physiology with other basic and clinical sciences.

c. Professional skills


b4 Define hematological tests: estimation of blood hemoglobin, bleeding &

clotting times, determination of the hematocrite value, the bleeding & clotting

times and blood groups.

c1 Recall how to record and read an electrocardiogram.

c2 Present physiological scientific data in a graphical form.

d. General and transferable skills


d1 Maintain honesty and integrity in all interactions with teachers, colleagues

and others with whom physicians must interact in their professional lives.

18

d2 Recognize the scope and limits of their role as students as well as the

necessity to seek and apply collaboration with other workers.

d3 Be responsible towards work.

4. Course content:

Topic

Lecture

hours

SDL

1. Water and electrolyte balance, acid-base balance and its

disturbance

1

2. Physiology of pain and its control +

3. Thermoregulation and fever, energy balance (obesity,

undernutrition and malnutrition)

+

4. Calcium homeostasis and physiology of bone +

5. Thyroid gland physiology +

6. Physiology of growth & growth disturbances 1

7. Glucose homeostasis and diabetes mellitus +

8. Cardiac performance and failure, ECG and arrhythmias,

arterial blood pressure – hypo & hypertension

1

9. Respiratory regulation-hypoxia, cyanosis & oxygen

therapy

1

10. Hemostasis, coagulation & fibrinolysis, anticlotting

mechanisms and their disorders

1

11. Blood groups and blood transfusion +

12. Physiology of RBCs and WBCs, anemia and WBCs

disorders

1

13. Detailed function of gastrointestinal tract, liver

physiology, jaundice and hepatic failure

1

14. Urine formation, renal function tests and renal failure 1

15. Physiology of the spleen and reticuloendothelial system-

immune mechanisms and their disorders

0.5

16. Neonatal physiology (cardiovascular, respiratory,

metabolic, hematological, endocrinal, gastrointestinal,

neurological changes and responses)

1

17. CNS physiology including Control of voluntary

movements and lesions, muscle state tone and its control,

extrapyramidal physiology, nerve and muscle physiology)

1

L: Lecture and SDL: Self directed learning

5. 4 - Student Assessment Methods

19

4.1 Short essays to assess knowledge

4.2 MCQs to assess knowledge and intellectual skills

4.3 Oral exam to assess intellectual, professional and general skills

6. References:

……………………………………………………………………….

……………………………………………………………………….

Medical Biochemistry , Biochemical Genetics And Molecular Biology Course Specifications A. Basic Information

Title: Medical Biochemistry, Biochemical genetics and Molecular Biology

Code: Program on which the course is given: Master of science in Medical and

clinical Genetics

Major or Minor element: Major

Department offering the program: Pediatric department

(Genetics unit)

Department offering the course: Department of Medical

Biochemistry and Molecular Biology

Academic year:

…………..............................................................................................

Level: First semester

Date of specification approval: …………………………………………..…………..

Credit Hours: 0.7

Lecture(s): 1 per week (10.5 total )

Co-coordinator:

…………..………………………………………………………...…

B. Professional Information

1. Course Aims:


a. To provide postgraduate students with a basic understanding of the

biological processes in humans at a molecular level and to correlate any molecular

defect or abnormality to medical problems

b. To provide postgraduate students with an integrated knowledge of how

energy is stored, retrieved and generated (metabolism).


20



a1 Describe the metabolic pathways of carbohydrates, lipids, and proteins,

their energetic, their sites, and the ways of their integration

a2 Point out sources and fate of ammonia in human body and the causes of

ammonia intoxication.

a3 Define the possible metabolic errors arising from deficiency of certain

metabolic enzyme

a4 Summarize the functions and deficiency diseases of vitamins and

minerals.

a5 Describe the pathogenesis and complications of some metabolic diseases

as diabetes and atherosclerosis.

a6 Explain the importance of enzymes in clinical diagnosis



Integrate basic biochemical facts with clinical diseases.



c1 Use the computer to retrieve and compare molecular biology data

c2 Solve any subject-related problems provided by staff



d1 Work in a team and cooperate with their colleagues and staff.

d2 Use basic computing skills and internet to fulfill problem-based learning

d3 Communicate relevant information with teaching staff and colleagues

3. Course content:

Topic Lecture hours SDL

Carbohydrate Metabolism 1.5 +

Lipid metabolism 1.5 +

General protein metabolism 1.5 +

Amino acid metabolism 1 +

Vitamins and Minerals 1

Biosignalling 1

Hyperbilirubinemia 1

Hyperuricemia and

Enzymes in clinical diagnosis

1


21

4. References:

5.1 Course Notes

i. Lecture notes

5.2 Essential Books (Text Books) i. Biochemistry for USMLE (Kaplan)

5.3 Recommended Books i. Lippincott Biochemical

5.4 Periodicals, Web Sites, … etc a. http://mic2.shams.edu.eg/moodle

b. www.medicaleducationonline.org

c. www.eul.edu.eg

Pharmacology And Pharmacogenetics Course Specification A. Basic Information

Title: Pharmacology Code:

Program on which the course is given: Master of science in Medical and

clinical Genetics



(Genetics unit)

Department offering the course: Department of Pharmacology

Academic year:

…………..............................................................................................



Credit Hours: 0.6

Lecture(s): 1 per week (9 total )

Co-coordinator:

…………..………………………………………………………...…


1. Course Aims:

The aim of this course is to provide candidates with an understanding of the basic

principles of pharmacology and pharmacogenetics which includes: medications,

their pharmacokinetics, metabolism, mechanisms of action, dosing, side effects,

drug interactions, compliance issues, and use in specific patient population.


http://www.medicaleducationonline.org/

http://www.eul.edu.eg/

22



a1 Discuss the pharmacokinetic, pharmacodynamic and pharmacotherapeutic

properties of different groups of drugs used in neonates, infants, children and

adolescents.

a2 Define the adverse and toxic effects of drugs and their management.

a3 Give an account on indications, limitations to the use of drugs,

contraindications and drug interactions.

a4 Define clinically relevant age, sex and genetic related variations that

affect response to drugs.

a5 Define the principles, the indications, the advantages and disadvantages of

various pharmacotherapy modalities.

a6 Recognize the rational and general guidelines for the use of drugs in the

proper dose in neonates, infants, children and adolescents and in special conditions

such in cases of liver and kidney impairment.



b1 Calculate accurately drug’s dosage, bioavailability, plasma half life and

volume of distribution in healthy and sick neonates, infants, children and

adolescents.

b2 Obtain and record a comprehensive drug history of the patient.

b3 Document drug adverse reactions.

b4 Observe, record and analyze the effect of drugs on biological tissues

b5 Write prescriptions.

b6 Audit prescriptions citing multiple drugs.



c1 Use safe drugs that allow optimal growth and development of neonates,

infants, children and adolescents.

c2 Prioritize treatment options in pediatric multiple organ disease

c3 Use knowledge and understanding of the pharmacological sciences to

formulate and apply the principles of scientific inquiry to address pharmacology-

related problems.

c4 Demonstrate competency in understanding, analyzing and interpreting

pharmacological data

c5 Think independently, evaluate and reflect, set tasks and select appropriate

and reasoned approaches to solve problems

c6 Integrate, analyze and summarize information relating to practical aspects

or current advances, issues and controversies within the pharmacological sciences

from a wide range of sources and evaluate this information to draw reasoned

conclusions or sustainable judgments

23



d1 Communication Skills:

Provide appropriate basic drug education to the patient and his family.

Demonstrate respect to all patients irrespective of their socioeconomic

levels, culture or religious beliefs and use language appropriate to the patient’s

culture.

d2 Collaboration with healthcare professionals: Communicate effectively

with other health care professionals to maximize patient benefits and minimize the

risk of errors.

d3 Life-long learning:

Understand the importance of life-long self-learning and show a strong

commitment to it.

Use current I.T. for appropriate drug database to reach information about

a specific medication.

d4 Ethical behavior:

Respect patient’s beliefs, values and privacy.

Respect ethics related to drug prescription and use especially to drugs

liable to produce abuse.

Recognize and effectively deal with unethical behavior of other members

of healthcare team.

3. Course content:

Topic

Lecture

hours

SDL

Drug therapy of heart failure. Diuretics Drug therapy of

shock

1 +

Drug therapy of dysrhythmias 1

Drug therapy of hypertension 1

Anemia. and hemostasis 1

Anti-emetics Drug therapy of acid related disorders Drug

therapy of constipation and diarrhea

+

Drug therapy of DM 1

Thyroid disorders. Calcium metabolism, Sex hormones

antagonists

+

Special chemotherapy: Antiviral, antifungal, antiprotozoal & 1

24

antituberculous

Immunomodulators +

Drug therapy of bronchial asthma. Corticosteroids 1

Cancer chemotherapy 1

Antihistaminic +

Analgesics, Anti-bacterials 1


4. References:

5.1 -Course Notes (paper and / or electronic)

5.2 -Recommended Books

- Bennett PN and Brown JM: Clinical pharmacology .Churchill Livingstone10th

edition.

- Rang HP, Dale MM, Ritter GM and Flower RJ: Rang and Dale’s

Pharmacology , Churchill Living stone 6th

edition.

5.3- Periodicals, Web Sites, etc

http://www.centerwatch.com/drug-information/fda-approvals/drug-

areas.aspx?AreaID=8

http://www.medilexicon.com/drugsearch.php?a=19

http://www.chilanti.com/olbooks/medbooks/Cochrane_Musculoskeletal_Group.ht

m

Microbiology & Immunology Course Specifications A. Basic Information

TITLE: MICROBIOLOGY & IMMUNOLOGY

CODE:


Clinical Genetics


Department offering the program: Pediatric department ( Genetics

unit)

Department offering the course: Department of Microbiology & Immunology

Academic year:

…………..............................................................................................



http://www.centerwatch.com/drug-information/fda-approvals/drug-areas.aspx?AreaID=8

http://www.centerwatch.com/drug-information/fda-approvals/drug-areas.aspx?AreaID=8

http://www.medilexicon.com/drugsearch.php?a=19

http://www.chilanti.com/olbooks/medbooks/Cochrane_Musculoskeletal_Group.htm

http://www.chilanti.com/olbooks/medbooks/Cochrane_Musculoskeletal_Group.htm

25

Credit Hours: 0.5

Lecture(s): 1 per week (7.5 total )

Co-coordinator:

…………..………………………………………………………...…


1. Course Aims:


1. Select the appropriate diagnostic tools of different microbiological

infections in pediatrics.

2. Understand the immunological aspects of pediatric infections and immune

prophylaxis.

3. Understand the importance of hospital-acquired infections and to learn the

appropriate measures of infection control.




a1 Recognize the epidemiological aspects of microbiological host- parasite

relationships, diagnostic lab methods, and typing of the organisms.

a2 Describe the microbiological aspects of the common and important

pediatric infections.

a3 Recall the immunological aspects of pediatric infections and immune

prophylaxis.

a4 Memorize hospital acquired infections and infection control measures.



b1 Choose the appropriate diagnostic tools for different pediatric infections.

b2 Classify the device- associated infections during hospital stay and

categorize the different measures to deal with such situations.



c1 Apply microbiologic and immunologic facts while assessing pediatric

problems

c2 Integrate facts with clinical signs and symptoms

c3 Correlate bacteriologic and basic immunologic data with patient outcome

c4 Predict the modes of clinical presentation of a particular pathogen



d1- Work in a team and cooperate with their colleagues and staff.

d2- Use basic computing skills and internet to fulfill problem-based learning

26

d3- Communicate relevant information with teaching staff and colleagues

3. Course content:

Topic

Lecture

hours

SDL

Epidemiological aspects , Host parasite relationship,

diagnostic lab methods and typing

1.5

Immunological aspects of pediatric infections and

immunoprophylaxis.

1.5

Hepatitis and other GIT infections 1.5

Upper and lower respiratory tract infections. 1

Septicemia., Bacteremia , FUO & CNS infections 1

Infection control measures ( Including device related

infections, ventilator associated pneumonia, IC measures in

the PICU)

1

Perinatal infections, congenital infections and IC measures in

the NICU

1



4.1 Quizzes at the end of each subject to assess understanding and weak

points

4.2 Written exam to assess knowledge, understanding and intellectual skills

4.3 Oral exam to assess the ability to identify and apply microbiological

knowledge and intellectual skills in a comprehensive oral way.

5. References:

5.1 Course notes: Medial microbiology and Immunology Department books

5.2 Essential books:

Elliott T, Worthington T, Osman H and Gill M Lecture Notes: Medical

Microbiology and Infection

Todd and Spickett: Lecture Notes: Immunology

5.3 Recommended Books

Medical Microbiology (Jawetz, Melnick, & Adelberg’s)

Medical Immunology (Parslow, Stites, Terr & Imoboden)

Practical Medical Microbiolology (Collee, Fraser, Marmion & Simmons)

Immunobiology (Janeway, Travers, Walport, Shlomchik)

27

Medical Microbiology & immunology (Levinson & Jawetz)

Basic Virology (Wagner)

Embryology Course Specifications A. Basic Information

Title: Embryology.


Clinical Genetics



Department offering the course: Department of Anatomy

Academic year:

…………..............................................................................................



Credit Hours: 1

Lecture(s):

Co-coordinator:

…………..………………………………………………………...…


1. Course Aims:


1. Understand the stages of normal prenatal development in human beings

2. Recognize the terminology used in human embryology

3. Describe the defects arising from faulty embryogenesis




a1 Describe the basic principles of embryologic development

a2 Recognize the terminology used in human embryology

a3 Recall the specific embryologic changes of different body systems

a4 Define the possible faulty embryologic development of different body

systems



b1 Identify the embryologic facts while assessing stages of gestation

b2 Integrate basic embryologic developmental facts of different systems

b3 Estimate embryologic changes with foetal outcome

28

b4 Locate the proper time of different system development



c1 Apply the embryologic facts while assessing stages of gestation

c2 Integrate basic embryologic facts with congenital abnormalities

c3 Correlate embryologic changes with foetal outcome

c4 Predict the different types of congenital abnormalities



d1 Work in a team and cooperate with their colleagues and staff.

d2 Use basic computing skills and internet to fulfill problem-based learning

d3 Communicate relevant information with teaching staff and colleagues

3. Course content:

Topic

Lecture hours SDL

General Embryology:

- Gametogenesis

- Development of the embryo

- Fetal membranes

2 +

Branchial or pharyngeal apparatus 2 +

The face, neck, nose & palate

The eye & ear

1 +

Human birth defects 2

Respiratory and digestive systems 1

Urogenital system 2

Cardiovascular system 1 +

Nervous system 2 +

The Endocrine glands 1 +

The musculoskeletal & integumentary

Systems

1 +



4.4 Evaluation during the semester: quizes at the end of each subject to assess

understanding and weak points

4.5 Written exam to assess knowledge, understanding and intellectual skills

4.6 Oral exam to assess the ability to identify and apply microbiological

knowledge and intellectual skills in a comprehensive oral way.

29

5. References:

5.1 Sadler T W: Langman’s Medical Embryology by. Williams and Wilkins

Company, 8th

edition,.

5.2 Moore KL and Persaud TVN: Review of Medical Embryology b. Saunders

Company6th

edition.

5.3 Cochard LR: Netter’s Atlas of Human Embryology. Saunders Company,1st

edition.

Parasitology Course Specifications

A. Basic Information

Title: Parasitology.


Clinical Genetics



Department offering the course: Department of Parasitology

Academic year:

…………........................................................................................ ......



Credit Hours: 0.5

Lecture(s): 1 per week ( total: 7.5 )

Co-coordinator:

…………..………………………………………………………...…

Course content:

Topic

Lecture hours SDL

Malaria 2

Toxoplasmosis 2

Trypanosomiasis 2

Hookworm 1.5


30

COMMUNITY, ENVIRONMENTAL, PREVENTIVE AND

OCCUPATIONAL MEDICINE, MEDICAL STATISTICS AND

RESEARCH AND BASICS OF NUTRITION COURSE

SPECIFICATIONS

Program on which the course is given: Diploma in Pediatrics



Department offering the course: Department of Community,

Environmental and Occupational Medicine.

Academic year:

…………..........................................................................



B. Basic Information

Title: Community, Environmental and Occupational Medicine.

Code: PE9008-PE9011

Credit Hours (Chr): 2

Lecture(s): 2hrs/week ( total: 30 )

Co-coordinator:

…………..………………………………………………

31

C. Professional Information

1. Course Aims:


1. Assess the health status of the infants and children.

2. Assess and monitor the worksite growth and nutritional status of the infants

and children

3. Suggest the appropriate measurements for prevention and control of

communicable and non-communicable diseases

4. Research for innovative solutions of priority health problems in childhood

5. Identify environmental health hazards

6. Understand the basic principles of research methodology and statistics




a1 Assess environmental health hazards and respond to disasters.

a2 Identify the natural history, methods of prevention, early detection,

management and control of common childhood diseases in the

community

a3 Select the epidemiological and statistical method suitable to conduct

research to solve different problems in practical fields

a4 Identify the health care system in Egypt and different health institutions.

a5 Learn how to diagnose and prioritize the childhood health

problems in the community

32



b1 Design epidemiological studies to investigate common childhood

diseases or understand new diseases

b2 Manage statistical data and interpretation of statistical results

concerning pediatric diseases

b3 Understand and criticize scientific medical papers concerning

pediatric health problems



c1 Attaining medical statistics skills

c2 Counsel families and communicate effectively with diseased children

c3 Perform field visits in order to identify major pediatric health problems

c4 Counseling and health education of parents for optimum health care



d1 Work efficiently within health care team

d2 Solve problems related to team work

d3 Develop leadership skills

d4 Acquire presentation skills

d5 Practice time management

d6 Use the computer

33

3. Course content:

Topic

Lecture

hours

SDL

General epidemiology 2 +

Principles of epidemiologic methods to assess

pediatric diseases

2 +

Hazards of indoor and outdoor pollutants on the

pediatric population

2 +

Malnutrition 1 +

Prevention and control of communicable diseases 2

Prevention and control of non communicable

diseases

2

Primary Healthcare 1

Child health programs 1

Quality improvement in child health care 1 +

Vital statistics in pediatrics 1

Medical statistics 14

Research ethics 1


34


4.7 Quizzes at the end of each subject to assess understanding and

weak points

4.8 Written exam to assess knowledge, understanding and intellectual

skills

4.9 Oral exam to assess the ability to identify and apply

microbiological knowledge and intellectual skills in a

comprehensive oral way.

5. References:

5.1 Gadallah MA: Community, Environmental and Occupational Medicine.

Department of community, environmental and occupational medicine.

Faculty of medicine, Ain-Shams University. 2008-2009

Student notes on Medical Statistics and research methods 2nd

edition, Cairo,

Jan 2009.

5.2 Gadallah MA & Moustafa ME Student notes on Medical Statistics and

research methods Department of community, environmental and

occupational medicine. Faculty of medicine, Ain-Shams University2nd

edition Cairo, Jan 2009.

5.3 Maxcy KF, Last JM, Wallace RB and Rosenau JM: Maxcy-Rosenau-

Last Public Health & Preventive Medicine 15th edition, Appleton and

Lange.

Medical geneticst course specifications University: AAiinn SShhaammss UUnniivveerrssiittyy Faculty: FFaaccuullttyy ooff MMeeddiicciinnee

Course specification


Clinical Genetics

Major element of program:

Department offering the program: Pediatric Department.

Department offering the course: Genetics unit.

http://www.bestwebbuys.com/Maxcy-Rosenau-Last_Public_Health_&_Preventive_Medicine-ISBN_9780838561850.html?isrc=b-search

http://www.bestwebbuys.com/Maxcy-Rosenau-Last_Public_Health_&_Preventive_Medicine-ISBN_9780838561850.html?isrc=b-search

35

Academic year: /

Level: Postgraduate, Semester 2, 3, 4. (1 module / semester)

Date of specification approval:

A. Basic Information

Title: Medical genetics.

Code:

Credit Hours: 17 credit hours.

Lecture: 153 hours.

Tutorial/Practical: 204 hours.

Total: 357s

B- Professional Information:

1. Program aims:

At the completion of th course, The candidate should:

1. Apply knowledge of formal genetics and basic sciences in the diagnosis

of genetic disorders.

2. Establish diagnoses by history taking, clinical examination and

investigations.

3. Calculate genetic risks.

4. Address all aspects of the healthcare needs of patients and their families.

5. Recognize the limitation of their own expertise and know when to seek

assistance of colleagues

6. Work as part of a team

7. Manage time and resources to the benefit of themselves, their patients

and colleagues.

8. Utilize effectively current methods in information technology

9. Are effective educators of both patients and colleagues.

10. Are able to take responsibility for their own educational needs and the

attainment of these needs.

11. Plan, conduct and write-up a research project

12. Debate the social, ethical and legal issues that affect the practice of

clinical genetics.

13. Use skills of life long learning to keep up to date with developments in

Medical and Clinical Genetics.

14. Develop new clinical practices based on analysis of developments in

genetic laboratory diagnostics

15. Carry out clinical audit and act on the results.

16. Accept the clinician’s role and responsibilities in providing high quality

patient care, setting and monitoring standards.

17. Participate fully in all Clinical Governance activities.

36

18. Have the requisite knowledge, skills and attitudes, to diagnose and

manage genetic aspects of a wide range of disorders.

2. Intended learning outcomes (ILOs):

a. Knowledge and understanding: By the end of the course the candidate will be able to demonstrate the ability to

apply knowledge of:

a1 - Basic human genetics terminology, principles of human and medical genetics

and basic patterns of biological inheritance and variation (both within families and

within populations), integrates the classical principles of human genetics with

modern molecular genetics, and demonstrates the clinical applications of this

knowledge for the diagnosis and management of a wide range of genetic disorders.

a2 - The importance of the three generation family history in assessing

predisposition to disease, highlighting the difference between a pedigree and

genogram

a3 - The role of genetic factors in health maintenance and disease prevention.

a4 - The difference between clinical diagnosis of disease and identification of

genetic predisposition to disease.

a5- The role of behavioral, social and environmental factors to modify or influence

genetics in the manifestation of disease.

a6- The influence of ethnicity, culture, related health beliefs and economics in

diagnosis and in the ability of the patient to use genetic information and services.

a7- The potential physical and/or psychosocial benefits, limitations and risks of

genetic information for individuals in the context of the family and community.

a8- The range of genetic approaches to treatment of disease (including

pharmacogenomics and gene therapy).

a9- The indications and resources for genetic testing and referral to genetic

specialists.

b. Intellectual capabilities:

By the end of the program the candidate will be able to:

b1- Processe, analysis, interprete, and reporte genetic conditions.

B 2- Select the appropriate investigational tool.

B 3- Interpret results.

B 4- Make conclusions.

B 5- Be capable of scientific discussion .

b 6- Select from different choices.

B 7- Creative thinking in solving problems.

37

c.Professional and practical skills : By the end of the program the candidate will be able to:

c1 Identifying patients who would benefit from genetic services.

c2 Record and analyse family history data.

c3 Obtain the medical history and carry out clinical examination as it relates

to genetic diseases.

c4 Diagnose genetic disease using clinical evaluation and genetic testing .

c5 Provide accurate information and effective genetic counselling to

individuals and families.

c6 Write clear summaries of genetic clinic consultations in post-clinic letters

to colleagues and patients.

c7 Formulate management plans for genetic aspects of genetic/hereditary

disorders.

c8 Perform risk calculation, including Bayes theorem.

c9 Carry out skin biopsy, hair root extraction and photography.

c10 Conduct literature searches and use medical genetic databases.

c11 Store and retrieve genetic data in single-disease genetic registers.

c12 Work effectively in a team with other colleagues providing genetic services.

c13 Liaise appropriately with colleagues from other specialists, including family

care workers.

c14 Make use of lay organisations to support patients and families with genetic

diseases.

c15 Communicate and explain genetic issues to colleagues and the lay public

c16 Work effectively with colleagues in other disciplines

d. General and transferable skills:

By the end of the program the candidate will be able to:

d1 Effectively using new information technologies to obtain

d2 Current information about genetics.

d3 Demonstrate interpersonal and communication skills that result in the

effective exchange of information and collaboration with patients, their families,

and health professionals.

d4 Skills of group working.

d5 Management skills.

3. Academic standards: (Benchmarks): The American College of Medical Genetics (ACMG).

38

Joint Royal colleges of physicians training board.

3. Course Contents:

2nd

semester

Title : Module A: Basic principles of genetics Code:

Credit: 6 lectures: 3.6 hrs/w Total: 54 hrs

Clinical/lab: 4.8 hrs/w Total: 72 hrs

Topic No. of hours

L C lab SLD

1. Genome Structure and Gene Expression 3

2. Organization and structure of chromosomes, The

Karyotype : nomenclature, interpretation of abnormal

karyotypes.

2 10

3. Cytogenetic diagnostic techniques 2 20

4. Chromosomal aberration and cell division 3 10

5. Congenital Malformations 3 8

6. Mutation : gene mutation, genome mutations. 2 4

7. Mechanisms of pathogenesis of genetic diseases. 2

8. Genetic regulation of cell functions 2

9. Pharmacogenetics . 2

10. Cancer genetics. 3

11. Genetics and genetic regulation of the immune

system.

3

12. Genetic control of growth and development. 2

13. Developmental genetics 3

14. Dysmorphology 3

15. Teratogenic factors and mechanisms of

teratogenesis.

2 2

16. Genetic Assessment and Pedigree Analysis 2 2

17. Patterns of inheritance 2 2

18. Gene mapping 3

19. Linkage & Association. 2

20. Population genetics. 2 2

21. Genetic Risk Assessment for Common Disease 2

22. The Human Genome Project. 2 2

39

23. Ethical and Social Issues in Clinical Genetics 2

Total 54 36 36


3rd

semester

3.2 Module B : Diagnostic, clinical and therapeutic genetics : 6 credit hours

Topic No. of hours

L C lab SLD

1. Molecular Diagnostic Techniques 3 18

2. Biochemical Diagnostic Techniques. 3 18

3. Inborn Errors Of Metabolism. 20 10

4. Mitochondrial Diseases. 2 1

5.. Genetic Diseases Of The Endocrinal System. 5 5

6. Genetic Diseases Of The Respiratory System. 5 5

7. Genetic Diseases Of The Cardio-Vascular System. 5 5

8. Genetic Diseases Of The Gastro-Intestinal System 5 4

9.. Genetic Diseases Of The Urinary System. 1 4

10. Dietary therapy : restriction – supplementation 1 2

11. Treatment of genetic diseases 3

12. Transplantation genetics 1

Total 54 36 36

4th

semester = module c + elective course

3.3 Module C : Clinical and applied. (5 credit hours)

Topic No. of hours

L T C SLD

Genetic Diseases Of The Blood. 3 5 5

Genetic Diseases Of The Immune System. 3

Genetic Diseases Of The Male Reproductive System. 3

Genetic Diseases Of The Female Reproductive System. 3 5 2

Genetic Diseases Of The Eyes & Vision. 3

40

Genetic Diseases Of The Ears & Hearing. 3

Genetics of connective tissue disorders 2 2

Genetic Diseases Of The Skin. 3 2 2

Genetic of Mental and Psychiatric Disorders. 2 2 2

Genetic Diseases Of The Nervous System 4 4

Genetics of neuromuscular disorders 3 4 2

Genetics of skeletal system disorders 3

Genetics of Craniofacial disorders 4 2

Genetic Counseling 2 4

Premarital Counseling 2 2 2

Pre-implantation Diagnosis 2

Prenatal Diagnosis 3 3

Genetic Screening 2

Fetal therapy 2

Newborn Screening 2

Forensic Genetics 2

Genetic Engineering 2

Proteomic Engineering. 2

Total 45 30 30

4. Teaching and Learning Methods

4.1 Lectures: using data show and overhead projectors

4.2 Practical Training:

4.3 Discussion sessions:

4.4 Collection of information using the internet

5- Student Assessment Methods

5.1 Logbook fulfillment to assess performance and attending the

different skills needed

5.2 Final written examination to assess theoretical knowledge,

interpretative and problem solving abilities through essay questions, and MCQs.

5.3 Oral examination to assess knowledge, attitude and communication

skills of the candidates

5.4 Practical examination through audio-visual presentation to assess

clinical, investigational, procedural and interpretative abilities

5.5 Clinical examination of short and long cases to assess clinical

skills and interpretative and analytical abilities

41

Assessment schedule of Genetics Course Assessment 1 ............................... end of second semester

Assessment 2 ............................... end of third semester

Assessment 3 ............................... Final assessment at end of program

.

6. list of references:

6.1 Essential Books (Text Books):

1- Emery and Rimoin's Principles and Practice of Medical Genetics .Author:

David L. Rimoin MD PhD, J. Michael Connor MD DSc, Reed E. Pyeritz MD PhD

Publisher: Churchill Livingstone, fifth edition, 2006

2- KliegmanRM, Jenson HB, Richard, EB and Bonita, FS: Nelson’s

textbook of Pediatrics:, 18th edition, Philadelphia. El-SEVIER / Saunders 2007.

3- Nussbaum et al. Thompson & Thompson's Genetics in Medicine 7Edition,

2007.

4- Metabolic & Molecular Bases Inherited Disease, Author(s): Scriver,

Charles R.; Beaudet, Arthur L.; Sly, William S.; Valle, David Oxford University

Press (OUP), 8th

edition, 2001

5- Smith's Recognizable Patterns Of Human Malformation Sixth Edition by

Kenneth Jones

6.2 Web Sites:

Online Mendelian Inheritance in Man (OMIM)

Online Multiple Congenital Anomaly/Mental Retardation Syndromes

(MCA/MR) PubMed http:/www.ncbi.nlm.nih.gov/omim/

GeneTests-GeneClinics

HuGENet http://www.marchofdimes.com/

Clinical databases:

London medical databases web site: http:/www.lmdatabases.com/

London medical databases series comprises: Winter-Baraitser Dysmorphology Database (WBDD)

Baraitser-Winter Neurogenetics Database (BWDB)

London Ophthalmic Genetics Database (GENEEYE)

Human cytogenetic database and catalogue of chromosome aberrations

in man

http:/www.forschungsportal.ch/unizh/p772.htm

Geneva Foundation for Medical Education and Research

http://www.target.com/gp/search/ref=pd_ttl_att_author_1/190-2016893-8100168?ie=UTF8&index=target&field-author=David%20L.%20Rimoin%20MD%20%20PhD

http://www.target.com/gp/search/ref=pd_ttl_att_author_2/190-2016893-8100168?ie=UTF8&index=target&field-author=J.%20Michael%20Connor%20MD%20%20DSc

http://www.target.com/gp/search/ref=pd_ttl_att_author_3/190-2016893-8100168?ie=UTF8&index=target&field-author=Reed%20E.%20Pyeritz%20MD%20%20PhD

http://www.studentconsult.com/content/default.cfm?ISBN=9781416030805

http://www.amazon.com/exec/obidos/search-handle-url/ref=ntt_athr_dp_sr_1?%5Fencoding=UTF8&search-type=ss&index=books&field-author=Kenneth%20Jones

http://www.ncbi.nlm.nih.gov/Omim/

http://www.nlm.nih.gov/mesh/jablonski/syndrome_title.html

http://www.nlm.nih.gov/mesh/jablonski/syndrome_title.html

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?myncbishare=nymclib&dr=citation

http://www.genetests.org/

http://www.genetests.org/

http://www.cdc.gov/genomics/hugenet/

http://www.marchofdimes.com/

http://www.lmdatabases.com/about_lmd.html#lddb

http://www.lmdatabases.com/about_lmd.html#lddb

http://www.lmdatabases.com/about_lmd.html#lndb

http://www.lmdatabases.com/about_lmd.html#geneeye

42

Elective courses: to choose from

8a- Molecular biology course specification University: Ain Shams University Faculty: of Medicine



Program on which the course is given: Master of Science in Medical and Clinical

Genetics Major or minor element of programs: Minor

Department offering the program: Department of pediatrics

Department offering the course: Department of pediatrics (Genetics unit).

Academic Level: Master – 4th

semester


A- Basic Information Title: Molecular biology course Code:

Credit Hours: 1 hour Lecture: 9 hours

Lab: 12

Coordinator

B - Professional Information

1- Course Aims:

The overall aim of this course is to provide the candidate with basic knowledge and

awareness in the field of molecular biology and genetics and their implications in

blood diseases and cancer biology. This course also aims to provide the candidates

with competencies to incorporate molecular biology diagnostic and therapeutic

tools in clinical practice

2- Intended Learning Outcomes (ILOs) from the Course:

a- Knowledge and understanding


a1. Understand the structure, function and organization of human genomes

a2. Describe the main principles of methods for preparation and extraction of

DNA and RNA.

a3. Understand the main principles of methods for DNA amplification (PCR,

RT-PCR, Real-time PCR, etc.)

a4. Identify the main principles of methods for DNA sequencing

a5. Describe the main principles of DNA and RNA blotting

a6. Understand the concepts of recombinant DNA technology

a7. Understand the applications of molecular biology techniques in the

diagnosis, taxonomy, species and strain differention of microorganisms.

43

a8. Understand the applications of molecular biology techniques in genetic

testing, in paternity testing, studying drug resistance, and vaccine and drug

development.

a9. Point out the principle of microarrays

b- Intellectual skills


b1. Integrate basic molecular biology facts with clinical examination.

b2. Identify the appropriate molecular biology technique required.

b3. Analyse and interpret the results molecular biology techniques and use

them in diagnosis of a clinical case.

b4. Identify tumor-associated genetic defects and relate them to patient

prognosis.

c- Professional skills


c1. Incorporate new molecular biology knowledge and tools into daily

patient care

c2. Use the computer to retrieve and compare molecular biology data

c3. Solve any subject-related problems provided by staff

c4. Equipping of the students with the specialized knowledge and skills

necessary for a research careers that demand knowledge of molecular biology.

Apply safety measures in the laboratory.

c5. Apply methods to prevent contamination of the lab and equipments.

c6. Follow proper method of disposal of biohazardous samples (infectious,

carcinogenic, etc.).

c7. Extract DNA

c8. Interpret the results of PCR and RT-PCR and DNA finger printing

c9. Awareness of the importance of informed consent that arise in relation to

storage of DNA samples and cell lines

d- General and transferable skills


d1. develop the skill of working in teams

d2. develop appropriate relationships with patient and family

d3. Use basic computing skills and internet to follow electronic lectures

d4. Communicate relevant information with teaching staff and colleagues

d5. Search gene and protein Database.

d6. Use molecular biology software.

3- Course content:

Basic principles in molecular biology No. of hours

L (1h) P SDL

44

1- Nucleic acid structure and organization 1

2- Cell cycle, DNA replication and repair 1

3- RNA transcription and processing 1

4- Regulation of gene expression 1

5-The Genetic code, mutation and protein

synthesis

1

6- Recombinant DNA technology 1 2

7- Techniques of genetic analysi: -Extraction of

DNA & RNA, PCR & RT-PCR, DNA

electrophoresis, Blotting technique, Microarray

1 9

7- Molecular biology of cancer: Oncogenes,

Tumor suppressor genes, Apoptosis Telomerase)

2

8- The Human Genome Project & advances in

DNA sequencing

1

9- Genetic variation & DNA finger printing 1

Total 9 12

L: Lecture, P: Practical and SDL: Self directed learning

4 - Student Assessment Methods

written examination to assess knowledge and understanding (MCQ)

5 -- List of References

5.1- Course Notes (paper and / or electronic)

Lecture notes provided by the staff of Medical Biochemistry and Molecular

Biology

………………………………………

5.2- Essential Books (Text Books)

…USMLE Step 1 Biochemistry (Kaplan)

Lippincott Biochemistry


http://www.web-books.com/MoBio/

http://www.coe.uncc.edu/~hhilger/EB_I_F_06/web_links_on_basics_of_molecular

_biology.htm

http://plato.acadiau.ca/courses/biol/Microbiology/Basics.htm

http://www.wiley.com/legacy/college/boyer/0470003790/animations/cell_structure

/cell_structure.htm

http://www.cellsalive.com/cells/3dcell.htm

http://www.web-books.com/MoBio/

http://www.coe.uncc.edu/~hhilger/EB_I_F_06/web_links_on_basics_of_molecular_biology.htm

http://www.coe.uncc.edu/~hhilger/EB_I_F_06/web_links_on_basics_of_molecular_biology.htm

http://plato.acadiau.ca/courses/biol/Microbiology/Basics.htm

http://www.wiley.com/legacy/college/boyer/0470003790/animations/cell_structure/cell_structure.htm

http://www.wiley.com/legacy/college/boyer/0470003790/animations/cell_structure/cell_structure.htm

http://www.cellsalive.com/cells/3dcell.htm

45

http://www.johnkyrk.com/DNAanatomy.html

http://www.johnkyrk.com/DNAreplication.html

http://www.johnkyrk.com/DNAtranscription.html

http://www.johnkyrk.com/DNAtranslation.html

http://www.rothamsted.ac.uk/notebook/courses/guide/

http://www.bio.com/protocolstools/protocol.jhtml?id=p1242

http://users.ugent.be/~avierstr/principles/pcr.html

http://depts.washington.edu/genetics/courses/genet371b-aut99/PCR_contents.html

http://www.sumanasinc.com/webcontent/anisamples/molecularbiology/pcr.html

[animation]

http://www.sumanasinc.com/webcontent/anisamples/molecularbiology/molecularbi

ology.html (animated techniques

8b- Medical statistics course specification University: Ain Shams University Faculty: of Medicine


Program on which the course is given: Master of science in Medical and Clinical

Genetics

Major or minor element of programs: Minor

Department offering the program: Pediatrics department-Genetics unit

Department offering the course: Community, Environmental and Occupational

Medicine

Academic Level: Master degree – 2nd

or 3rd

or 4th

semester



Title: Medical statistics course

Code:

Credit Hours: 1 hour

Coordinator

Community, Environmental and Occupational Medicine Department

B - Professional Information

1- Course Aim:

http://www.johnkyrk.com/DNAanatomy.html

http://www.johnkyrk.com/DNAreplication.html

http://www.johnkyrk.com/DNAtranscription.html

http://www.google.com/url?sa=D&q=http%3A%2F%2Fwww.johnkyrk.com%2FDNAtranslation.html

http://www.rothamsted.ac.uk/notebook/courses/guide/



http://users.ugent.be/~avierstr/principles/pcr.html

http://depts.washington.edu/genetics/courses/genet371b-aut99/PCR_contents.html%20%5banimation%255d

http://depts.washington.edu/genetics/courses/genet371b-aut99/PCR_contents.html%20%5banimation%255d

http://www.sumanasinc.com/webcontent/anisamples/molecularbiology/pcr.html

http://www.sumanasinc.com/webcontent/anisamples/molecularbiology/molecularbiology.html

http://www.sumanasinc.com/webcontent/anisamples/molecularbiology/molecularbiology.html

46

To enable the Master candidate to plan, conduct, analyze and interpret the results

of a research in his specific field. This course unit introduces the application of

statistical ideas and methodology to medical research.

2- Intended Learning Outcomes (ILOs) from the Course:

a- Knowledge and understanding


a1 - Define medical statistics and identify uses and importance of medical statistics

in medical research

a2 – Define:

Types of variables.

Descriptive statistics.

Presentation and summarization of data.

Measures of central tendency and scatter.

Principles of probability and probability distributions.

Concepts of inferential statistics: confidence interval and hypothesis testing.

Different tests of statistical significance.

Difference between parametric and nonparametric tests of significance.

Correlation and regression

Concept of statistical modeling using multivariable and multivariate statistical

methods.

Combining evidence from different studies and meta-analysis

Importance and methods of sampling and how to determinate the suitable sample

size.

Different types of research methodology:

observational and intervention studies and the different statistical issues related to

the design, conduct, analysis and interpretation of the results of each study type.

Ethical aspects of medical research including those specifically applied to clinical

trials.

b- Intellectual skills


b1 - Interpret correctly the results of statistical analyses and critically evaluate the

use of statistics in the medical literature.

b2 - Integrate and evaluate information from a variety of sources.

c- Professional skills


c1- Select appropriate study designs to address questions of medical relevance

47

c2 - Select and apply appropriate statistical methods for analyzing data typically

encountered in medical applications.

c3- Use selected software packages for statistical analysis and data management.

d- General and transferable skills


d1 - Work effectively in a group from different backgrounds.

d2 - Respects the role of staff and co-staff members regardless of degree or

occupation.

d3 - Communicate effectively with professional statisticians and the wider medical

community, including the ability to present results of statistical analyses through

written and oral presentations

d4 - Use of computer data bases and other computer skills.

d5 - Handle data appropriately and analyze them through: decision processes,

objective criteria, problem definition, project design and evaluation, risk

management, teamwork and coordination.

d6 - Learn independently with open-mindedness and critical enquiry.

3- Course content:

Topics

T C/P

Introduction to medical statistics and its uses x x

Types of variables and Descriptive statistics x x

Graphic presentation of data x x

Introduction to probability theory and rules x x

Sample and population: sampling distribution of mean and proportion x x

Confidence interval of a mean and a proportion x x

Confidence interval of a difference between two mean /proportion x x

Testing a hypothesis about population mean/proportion x x

Testing a hypothesis about the difference between two

means/proportion

x x

Comparing between more than two means-Introduction to factorial

analysis

x x

Cross-tabulation and introduction to categorical data analysis x x

Simple correlation and simple regression x x

Introduction to multivariable and multivariate analysis x x

Study designs: observational studies x x

Study designs: Intervention studies: clinical trials x x

48

Study designs: Experimental animal studies x x

Study designs: Bias and Confounding x x

Ethical issues in medical research x x

Sample size estimation for continuous and binary outcome measures. x x

Meta-analysis and publication bias. x x

T: Tutorial and C/P: Clinical or Practical and SDL: Self directed learning

4 - Student Assessment Methods

4-1 Written exam to assess knowledge and understanding and will concentrate on

problem solving questions

5 - List of References

5.1- Course Notes (paper and / or electronic)

Student Notes on Medical Statistics and Research Methods. Prof. Mohsen Abdel

Hamid and Dr Moustafa El Houssinie. Department of Community, Environmental

and Occupational Medicine.

5.2- Essential Books (Text Books)

Statistics in Clinical Practice. avid Coggon. BMJ Books. 2nd

edition 2003

5.3- Recommended Books

Handbook of Epidemiology. Springer 2005


www.brettscaife.net/statistics/introstat/

onlinestatbook.com/rvls/

www. Epidemiolog.net

http://www.shef.ac.uk/scharr/spss/

VI – Your log book

1- Introduction

49

The aim of this book is to give you a guide to the expectations for each item. It will

be a guide for both you and your teachers to what you should be seeing and doing.

It will give you a list of the important topics that you should think about and should

be covered in:

1. Clinical or practical sessions

or

2. Tutorials

or

3. Self-directed learning (SDL)

For each item there is also a list of

1. Clinical conditions or Practical sessions to be seen or

attended (According to each degree)

2. Practical procedures to be seen and done

Remember

This document is only a guide. It is not an exhaustive list. It is not just a

checklist to score points. It is a guide to encourage you to read and learn more.

This book is for your benefit. It will form a record of your clinical training and

experience.

2 – Supervisors

Prof. Mohamed Saad Zaghloul

Prof. Solaf Mohamed Elsayed

Prof. Rabah Mohamed Shawky

Prof. Mohamed Abd-Eladl El-Sawi

Prof. Karam Abdelaleem

Prof. Ezzat Elsobky

3–Tables for Training Records

Candidates are required to fulfill 75% of the listed activities in order to be eligible

for the exam entry. The minimum number required for each activity = 75%. You

are free to attend more and record your extra attendance.

Weekly Department Plan

(Medical Genetics)

Day /time Saturda

y

Sunda

y

Monday Tuesday Wednesd

ay

Thursd

ay

Bedside education * * * * * *

Conference 11:30

Clinical round * * *

Genetics Clinic * * *

Genetics Lab * * *

Genetic seminars 9-11

50

other non- weekly activity

Medical Genetics conference

Thesis discussion in Medical Genetics

Requirements

Candidates are required to fulfill 75% of the listed activities in order to be eligible

for the exam entry. The minimum number required for each activity = 75%. You

are free to attend more and record your extra attendance.

Genetic Conferences attendance

(NB. Minimum number required is 4)

No

Da

te

Pla

ce

Topics Supervisor

signature

1

2

3

4

Genetics Seminars attendance


No Date Place Topics Supervisor

signature

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

17

51

18

19

20

21

22

23

24

25

26

27

28

29

30

Genetics and pediatrics Thesis attendance


No Date Place Name of the thesis Supervisor

signature

1

2

3

4

5

6

7

8

9

10

Genetics Clinics attendance


No Date Place Name of the Clinic Supervisor

signature

1

2

3

4

5

6

52

7

8

9

10

11

12

13

14

15

16

17

18

19

20

21

22

23

24

25

26

27

28

29

30

31

32

33

34

35

36

37

38

39

40

41

42

43

44

45

53

46

47

48

49

50

51

52

53

54

55

56

57

58

59

60

Bedside Education (Tutorials) Attended


No Date Place Name of the tutorial Supervisor

signature

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

17

18

54

19

20

21

22

23

24

25

26

27

28

29

30

31

32

33

34

35

36

37

38

39

40

41

42

43

44

45

46

47

48

49

50

51

52

53

54

55

56

57

55

58

59

60

Karyotype Attended


No Date Place Name Supervisor

signature

1

2

3

4

5

6

7

8

9

10

Genetics Case presentations


No Date Place Diagnosis Supervisor

signature

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

56

16

17

18

19

20

Patients to be seen with the following problems

(A minimum of 75% of total cases is required to be seen)

Primary diagnosis Number Supervisor

signature Required Date

IEM

Aminoacidopathies including

Phenylketonuria, homocytinuria and

urea cycle disorders

5

GSD 1

MPS 5

Other Lysosomal storage diseases 5

Chromosomal disorders

57

Down syndrome 8

Trisomy 13 2

Trisomy 18 1

Turner syndrome 4

Klinefelter syndrome 5

Fragile X 5

Chromosome

deletion syndromes

1

Developmental and behavioral Genetics

Developmental delay and mental

retardation

10

Autism spectrum disorders 1

Common behavioral problems 1

Dysmorphic syndromes

Rubinstein Taypi syndrome 2

Syndromes presented with obesity 1

Absent radius related syndromes 1

Cornelia deLange syndrome 2

Holoprosencephaly 1

FGFR syndromes 2

IUGR syndromes 2

Overgrowth syndromes 1

Neural tube defects 2

Dermatological Disorders:

58

Oculocutaneous albinism 3

Ichthyosiform Dermatoses 3

Epidermolysis Bullosa 1

Ectodermal Dysplasias 1

Connective Tissue Disorders

Marfan Syndrome and Other

Disorders of Fibrillin

2

Ehlers-Danlos Syndrome 1

Genetic counseling Recurrent abortion

5

Premarital genetic counseling 5

Endocrine disorders

Growth retardation/short stature 6

Disorders of sexual development ( 5

Thyroid disease 1

Pubertal disorders 1

Pituitary disorders 1

Neurological disorders

Microcephaly 5

Neurocutaneous syndromes 1

Spinal muscle atrophy 1

Muscular dystrophies 2

59

Skeletal disorders and metabolic bone diseases

Achondroplasia 1

Osteogenesis imperfecta 1

Deafness and ear malformation

Waardenburg syndrome 1

Goldenhar syndrome 1

Treacher Collins syndrome 1

Practical skills (Agreement Scale)

Item

No

Ob

serv

ed

Da

te

assi

sted

Da

te

Do

ne

ind

epen

den

tly

(A,

B,

C)

Acc

ord

ing

to

eac

h

dep

artm

ent

Da

te

Su

per

vis

or

sig

na

ture

Karyotype

1

2

3

4

5

6

7

8

9

10

PCR

1

2

3

FISH 1

2

60

Aminogram 1

2

Ferric chloride 1

2

MPS spot test 1

2

a- Poor b- Satisfactory c- Excellent

Interpretation of investigative tools

(Minimum number required for each is stated)

Imaging

1. Plain X rays (5)

No Date Pt initials,

AGE/SEX Indication

Diagnosis Supervisor

signature

1

2

3

4

5

2. CT / Magnetic resonance imaging of different organs

No Date PT initials,

AGE/SEX Indication

Diagnosis

Supervisor

signature

1

2

3

Karyotype

No Date Pt initials,

AGE/SEX Indication

Diagnosis Supervisor

signature

1

2

3

4

5

6

7

8

61

9

10

5 - Log book preview

The candidate logbook will be reviewed and patients seen/ skills performed

summarized by diagnosis groups during the semester evaluation and at the end of

the course in the table below. This reflects the number of activity done by

category. (According to each degree) The results of this review will be totaled in

the summary chart below.

Summary

Semester 1st 2

nd 3

rd 4

th Total

Activity No No No No

Genetic Conferences attendance 1

Genetics Seminars attendance 5

Genetics and pediatrics Thesis

attendance 2

Genetics Clinics attendance

VII - Head Of Department Approval For The Exam Entry

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

_____

VIII – THESIS FOLLOW UP

62

ازمش٠ش اصف اغ ؼب /

ػ اطبت /

( م١ذ ذسجخ ) بجغ١زشا

ثمغ /

رمش٠ش اغبدح االعبرزح اششف

لطغ شطب ذذدا جغ ابدح اؼ١خ ثذأ

إز اجغ وزبثخ امذخ أشه ػ اإلزبء

لطغ شطب ذذدا اجضء اؼ ثذأ

إز ازذ١ أشه ػ اإلزبء

لطغ شطب ذذدا بلشخ ازبئج ثذأ

إز ازذش٠ش زبء أشه ػ اإل

لطغ شطب ذذدا اشاجؼخ ابئ١خ غ اششف ثذأ

إزذ ربب أشه ػ اإلزبء

------------------------------------------------------------------------------------------------

سأ اغبدح اششف

ذ ام١ذ إعزشاس ل١ذ اطبت

شطت ل١ذ اطبت

ر رشى١ جخ ابلشخ ؼ ربس٠خ ازشى١ / /

ال

ذ / شطت ام١ذ

64



ػ اطبت /

ام١ذ ذسجخ ) بجغ١زش (

ثمغ /



إز اجغ ه ػ اإلزبء وزبثخ امذخ أش




إز ازذش٠ش أشه ػ اإلزبء



------------------------------------------------------------------------------------------------

بدح اششفسأ اغ



ربس٠خ ازشى١ / / ر رشى١ جخ ابلشخ ؼ

ال


66



ػ اطبت /


ثمغ /

غبدح االعبرزح اششفرمش٠ش ا



لطغ شطب ذذدا ثذأ اجضء اؼ


ذذدا لطغ شطب بلشخ ازبئج ثذأ



إزذ ربب شه ػ اإلزبء أ

------------------------------------------------------------------------------------------------





ال


68



ػ اطبت /


ثمغ /







إز ازذش٠ش شه ػ اإلزبء أ



------------------------------------------------------------------------------------------------





ال


70



ػ اطبت /


ثمغ /



إز اجغ أشه ػ اإلزبء وزبثخ امذخ





لطغ شطب ذذدا ذأ اشاجؼخ ابئ١خ غ اششف ث


------------------------------------------------------------------------------------------------




ربس٠خ ازشى١ / / ر رشى١ جخ ابلشخ ؼ

ال


71



ػ اطبت /


ثمغ /




لطغ شطب ذذدا ثذأ اجضء اؼ






------------------------------------------------------------------------------------------------





ال


73

VIII – EVALUATION FORMS

Evaluation Form (at the end of each semester) To be completed at -------------------------------------

Candidate

Supervisor

Location

Aim of training

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

Agreed educational objectives and timescale in which objectives should be

achieved.

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

Comments by Candidate

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

Comments by Supervisor

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

Date of next meeting

Signed by candidate

Signed by Supervisor

Date

75



Candidate

Supervisor

Location

Aim of training

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________


achieved.

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________


__________________________________________________________________

__________________________________________________________________

__________________________________________________________________


__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________


Signed by candidate


Date

77



Candidate

Supervisor

Location

Aim of training

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________


achieved.

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________


__________________________________________________________________

__________________________________________________________________

__________________________________________________________________


__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________


Signed by candidate


Date

79



Candidate

Supervisor

Location

Aim of training

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________


achieved.

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________


__________________________________________________________________

__________________________________________________________________

__________________________________________________________________


__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________


Signed by candidate


Date

81

Degree Program Evaluation Form By The Candidate

To be completed at the end of your degree.

Please consider each pair of statements and decide which most clearly reflects your

view and tick one box or answer the question.

I. Individual Information

1. Are you a graduate of ASU?

yes no to some degree

2. Year and semester when studies began:

II. General Questions

1. What are the advantages/disadvantages of the general study environment at the

University ASU?

2. What were your expectations when you applied to the degree?

3. Do you feel that the degree program prepares you well for your future studies or

employment according to the demands and expectations of those institutions?


4. Has the time limit of the program (two or three academic years) caused you any

difficulties or inconveniences?


III. Structure of Degree Program

1. Did you receive enough guidance in planning your study schedule in the

beginning of the program?


2. What were the main difficulties in the planning of your study schedule?

3. What is your general opinion on the structure of the degree program?

4. In your opinion, does the degree program offer a good balance of lectures,

seminars, conferences, and book exams?


82

a) General Studies

i) Do you feel that you have received enough guidance on academic writing?


ii) Do you feel that you have acquired sufficient knowledge on research skills (eg.

quantitative and qualitative research methods)?


b) Courses

i) Have you had some special difficulties in completing some of the courses?

Please specify.

ii) Has there been a sufficient variety of courses offered for your optional studies?


iii) Have you received enough guidance for the preparation of your thesis?


IV. Concluding Points

1. Did the degree program meet your expectations?


2. What aspects of the degree program do you particularly like?

3. What aspects of the degree program do you particularly dislike?

4. What are your suggestions on how to improve the program?

Thank you!

master of science in medical and clinical...

Documents