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Maternal Mental Illness Antenatal and postnatal depression Dr Andrew Mayers [email protected]

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Maternal Mental IllnessAntenatal and postnatal depression

Dr Andrew Mayers

[email protected]

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Maternal Mental Illness

Overview What is maternal mental illness? Consequences for child and the mother Effect on relationship between them Types of illness

Antenatal depression Antenatal anxiety Postnatal depression

We will look at these illnesses in this session Serious illnesses (later session)

Postpartum psychosis Maternal OCD

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Who am I? What am I doing here?

First worked in Hampshire perinatal MH unit in 2003

Co-ordinated research programme

Now associated with Dorset MBU in Bournemouth

Formerly, Director of PANDAS

National pre- and postnatal mental illness charity

Member of Maternal Mental Health Alliance

Member of Perinatal Mental Health Partnership

Commissioned by NHS in Hampshire and IOW to ‘train’ health profs

Presented at CPHVA conference, York (Oct 2013)

For more information:

http://www.andrewmayers.info/perinatal-mental-health.html

Follow me on Twitter @DrAndyMayers

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Postnatal period

Correlation between antenatal mental distress and postnatal maternal distress and antenatal attachment and postnatal attachment...PREVENTION!!

Change/transition Psychological distress (anxiety, stress, low

mood) Stress, daily

hassles of bring up an infant,

change in identity, relationship

changes, loss of control …

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Impact on developing child

Significant intellectual deficits found in children (aged 4) whose mothers had suffered with depression (Cogill, et al., 1986)

Postnatal depression may be associated with later difficulties in child’s adjustment-problems when starting school

Anxiety in girls; conduct problems in boys

Affects child’s social and emotional development

Ability to form relationships

Depression in fathers associated with emotional and behavioural outcomes in children aged 3½ years

Increased risk of conduct problems in boys

Effects remain after controlling for maternal postnatal depression (Ramchandani et al., 2005)

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Impact of postnatal depression

PND associated with several negative outcomes Increased marital stress Disturbances in child’s emotional and cognitive

development (Cogill, et al., 1986)

Children of dep mums more likely to be associated with: Insecure attachment Eating difficulties Sleep disturbance Being overly clinging

PND affects mum’s ability to cope with care of baby See Murray, et al., 2003

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Impact of maternal sensitivity

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The importance of attachment

Why is attachment important between mother and infant? Early mother–infant bond may have sig. impact on

developing infant (e.g. Bowlby, 1953; Ainsworth, 1993) Infant’s internal working model (IWM) is very important

Expectations about themselves in relation to others Model of self and of other

If infant’s carer attends positively and responds to needs Infant has positive IWM:

High self-worth, availability of others, resolution of crises

Infant’s carer inconsistent response and attention Infant’s has negative IWM:

Low or ambivalent self-worth, unavailable others, crises not resolved

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What can health visitors do?

Health visitors CAN play a crucial role in identifying mental health difficulties Spotting signs and risk factors Early intervention Signposting to relevant services

For the well-being of mother AND the developing infant

Important to: Acknowledge distress Offer an empathic response Assess risk

But WHAT are we looking for?

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Antenatal depression

“At any one time during pregnancy one in every ten women will be depressed and around one in every thirty will be depressed in pregnancy and the postnatal period” Dr Vivette Glover

Symptoms Chronic anxiety Guilt Incessant crying Lack of energy Relationship worries

Worrying their partner may leave once the baby is born

Conflict with parents Isolation Fear to seek help

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Causes of antenatal depression

Physical Body changes!

Weight gain (only clothes that fit are tatty or were previous used for ‘painting’), swollen breasts, dizziness and nausea, bladder issues, exhaustion, heart rate, blood pressure, swollen ankles/wrists...

Hormonal changes Nausea – morning sickness

For some mums-to-be these experiences (and/or perception of them) worse than for others

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Causes of antenatal/postnatal depression

Emotional causes

Mood swings

First-time mum experience

Change of identity

Previous pregnancy difficulties

Complications, difficult labour, miscarriage, stillbirth…

Chronic anxiety 

Especially new mums

NEVER ‘dismiss’ anxiety - EMPATHISE

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Causes of antenatal depression

Social causes Antenatal depression is NOT new (despite only being

recognised relatively recently) Mums just did not have chance to talk about it then

Family support Families often lived closer together than they do now

Work and finance Greater pressure for mum to work in modern age

Expectations Media perceptions of perfect nursery/bedroom Pressure to live to societal standard

Good enough mum

NOTE: Majority of cases of antenatal depression disappear at birth BUT - one third of these mums develop postnatal depression

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Post-natal depression (PND)

Baby blues (see O’Hara, 2009)

Two to four days after birth (quite normal – but not PND) Emotional/liable to burst into tears, for no apparent

reason Difficult sleeping (even when baby permits) Loss of appetite Feeling anxious, sad, or guilty Questioning maternal skills

Effects up to 75% of mums May relate to changes in post-birth hormone levels

Or could be related to being in hospital Key is that this doesn't last long – usually only a few days

If it persists it may develop into PND

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PND: DSM-5 diagnosis

PND needs same DSM-5 diagnosis as major depressive disorder But relates specifically to the peripartum period

Pregnancy and/or within 4 weeks of birth Five (or more) of (but at least one of symptom 1 or 2)

1. Depressed mood (for most of day, nearly every day…)

2. Markedly diminished interest in all/almost all activities

3. Significant weight loss (not dieting) or decease/increase appetite

4. Insomnia or hypersomnia

5. Psychomotor agitation/retardation (observable)

6. Fatigue or loss of energy

7. Feelings of worthlessness or excessive/inappropriate guilt

8. Diminished ability to think/concentrate or indecisiveness

9. Recurrent thoughts of death… suicidal ideation/attempt/plan

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PND: Features

Additional features may also indicate presence Sense of inadequacy, inability to cope Feeling guilty Being unusually irritable

Which makes the guilt worse Being hostile/indifferent to husband/partner/baby Losing interest in sex Panic attacks Excessive unwarranted anxiety

Such as being alone in the house Obsessive fears about the baby's health or wellbeing

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PND: Prevalence

PND affects about 10% of new mums Compare to baby blues (25-75%)

Although DSM-5 states ‘must be within 4 weeks of birth’ Most clinicians/researchers extend this to several months

Vulnerable mums usually referred in ‘perinatal’ period During pregnancy up until baby is 1 year

Can come on gradually or all of a sudden Can range from being relatively mild to very hard-hitting About 50% PND women afraid to tell health professionals

about it Scared it will lead to social services taking child away Or that they would be seen as bad mothers

See O’Hara (2009) for good overview of PND

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PND: Causes

Causes of PND uncertain But there are a number of known risk factors (Kim, et al.

2008)

Having had depression before Especially PND

Not having a supportive partner Having a premature or sick baby Having lost your own mother as child Having had several recent life stresses

Bereavement, unemployment, housing or money problems

Poor sleep (see later)

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PND: Causes

Some additional risk factors for PND Shock of becoming a mother

Women often unprepared for physical impact of childbirth

Plus new and daunting skills to learn New full time responsibility Helpless human being who cannot communicate

Other than cry (distressing in itself) Some mums get anxious when they don’t hear

crying! Lie awake listening out

Loss of freedom and independence Exhaustion and fatigue

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PND: Causes

Hormones Oestrogen and progesterone affect emotions

Levels of progesterone are very high during pregnancy PND maybe due to sudden drop progesterone after

birth In one study women given progesterone to try prevent

PND But it had the reverse effect and got worse Oestrogen treatment via patch can be helpful

Otherwise, hormones not a major influence Diet

Lack of certain nutrients during pregnancy may cause PND Omega 3 oils (found in oily fish, seeds and nuts) Magnesium (leafy green vegetables and seeds) Zinc (seeds and nuts)

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PND Treatment

Antidepressants Huge amount of evidence of benefit in treating

depression First line choice in most adults BUT it is not that simple in PND

Some antidepressants serious side effects and interaction

Consider this if mum is breastfeeding Some antidepressants are not safe for infants

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Medication for PND – what is safe?

Tricyclic antidepressants Lower known risks than other antidepressants

But more dangerous in overdose SSRIs (after 20 weeks) greater risk hypertension in

neonate Fluoxetine fewer known risks of SSRIs Paroxetine (in 1st trimester) some risk foetal heart

defects Venlafaxine some risk high blood pressure (at high

doses) Most antidepressants pass into the breast milk

Imipramine, nortryptiline and sertraline - at relatively low levels

Citalopram and fluoxetine - at relatively high levels

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PND Treatment

Counselling and talking therapies (CBT etc.) very effective

Group or individual care

BUT rare - can take time to get into a programme

We need more Perinatal Mental Health teams!

Self-help strategies

Counselling (listening visits)

Brief cognitive behavioural therapy

Interpersonal psychotherapy

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Whooley questions

During the past month…

1. Have you often been bothered by feeling down, depressed or hopeless?

2. Have you often been bothered by having little interest or pleasure in doing things?

Consider a third question:

Is this something you feel you need or want help with?

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What we have learned

We have examined several aspects of maternal mental illness What is maternal mental illness? Types of illness

Antenatal depression Antenatal anxiety Postnatal depression

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Exercise

Group task Are Whooley questions enough? What are the risk factors? What signs should we watch out for? Why are mums reluctant to tell us about mental health

problems? How far should we pursue this?