mcb 142/icb 163, fall 2008 © abby dernburg
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MCB 142/ICB 163, Fall 2008 © Abby Dernburg
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MCB 142/ICB 163, Fall 2008 © Abby Dernburg
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MCB 142/ICB 163, Fall 2008 © Abby Dernburg
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MCB 142/ICB 163, Fall 2008 © Abby Dernburg
Quiz and midterm dates on syllabus posted on course website!http://mcb.Berkeley.EDU/courses/mcb142/
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MCB 142/ICB 163, Fall 2008 © Abby Dernburg
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MCB140, Jan. 23, 2008
“Cancer Free at 33, but Weighing a Mastectomy”
The New York Times, Sunday, Sep. 16, 2007
Deborah Lindner, 33, did intensive research as she considered having a preventive mastectomy after a DNA test.
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MCB140, Jan. 23, 2008 The New York Times, Sunday, Sep. 16, 2007
60-80%
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MCB140, Jan. 23, 2008 The New York Times, Sunday, Sep. 16, 2007
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MCB 142/ICB 163, Fall 2008 © Abby Dernburg
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Universal genetic code
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metaphase
prometaphase
Mitosis is the mechanism by which dividing cells partitiontheir chromosomes to produce genetically identical daughters
anaphaseprophase
interphase telophase
Mitosis=M-phase
centrosome
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1n
1n
Sexual reproduction relies on MEIOSIS
2n
haploid
diploid
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Chromosome segregation during meiosis is accomplished through homolog pairing, synapsis, and recombination
Meiotic S-phase
leptotene
gametes
zygotene
pachytene
Meiosis I
Meiosis II
Meiotic prophase
homolog pairing
& synapsis
chromosomecondensation
“crossover”recombination
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A typical human female produces approximately
450 mature eggs over the course of her lifetime.
Eggs are big cells, requiring a serious investment of energy.
A typical human male produces about 60 million mature sperm per milliliter (cm3) of ejaculate.
(In 1940 it was 113 million)
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recombinant
parental
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