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STAR GLOBAL 2015 SECURING THE MANUFACTURING PROCESS OF VACCINES USING CFD
Philippe B Vincent
AGENDA
Our Organization Our project Simulations Computational Geometry Boundary Conditions Numerical methodology
Some Results Conclusion
OUR ORGANIZATION
OUR ORGANIZATION
Engineering Services
Technologies
Metrology Services
Creaform was founded in 2002 and acquired by Ametek in 2013 Head office in Leacutevis Queacutebec Canada We develop manufacture and distribute innovative portable 3D measurement technologies and we are a leading provider of 3D engineering services 150 distributors worldwide We employ more than 385 people
Creaform helps companies to seamlessly create simulate verify and collaborate in 3D
MORE THAN 2000 CUSTOMERS
Aerospace
Consumer Products
Mass Transportation
Energy
NUMERICAL SIMULATION DEPARTMENT
bull Computational Fluid Dynamics (CFD) ndash Software StarCCM+ from CD-Adapco ndash Simulations using 3D scans ndash External aerodynamics ndash Conjugate heat transfer and thermal modeling ndash Free surface flows ndash Gas dispersion ndash Etc
bull Finite Element Analysis(FEA)
ndash Software Nastran ANSYS LS-Dyna ndash Dynamic response (Random amp Sine vibration
transient) ndash Composite analysis ndash Modal and buckling analysis ndash Contact and assembly ndash Etc
OUR PROJECT
ABOUT OUR PROJECT
bull Business Area Pharmaceutical building
services
bull Customer Project Process design installation and commissioning of a vaccine filling production line in a positive air pressure cleanroom
bull Schedule ~2 years (design to commissioning)
bull Process The RABS unit (Restricted Access Barrier) is equipped with a vials conveyor and the vaccine filling instruments The machine fills hundreds of vials per minute
RABS and vaccine filling
Cleanroom
ABOUT OUR PROJECT Detailed requirements of simulations Provide easily understood visual results of flow interactions
in the RABS to complement smoke tests Identify upward flow on critical plane 6 in above the vials
conveyor Recommend and test mitigation measures for improper
flow paths around non-sterile components of the machine
This brings up challengeshellip
bull Manage the large and detailed geometry
bull Precisely reproduce the very sensible flow in the plenum
bull Evaluate secondary air flow rates through wall openings of conveyor and cleanroom access door
Responsibilities of Creaform
CAD reproduction CFD simulations of HVAC Design improvements
ABOUT OUR PROJECT
RABS (Restricted Access Barriers)
bull Protection against contamination
bull Physical and aerodynamic barrier
bull Cleanroom Grade B
bull Inside of RABS Grade A critical zone
(glass doors with gloved access)
The extent of separation between the process and the contamination sources (ex People) determines the grade level of the protected zone
SIMULATIONS
COMPUTATIONAL GEOMETRY
Available data Cleanroom blueprints STL files of equipment
Final CFD numerical geometry Cleanroom walls and furniture Physical barrier with gloved access Control panel Machine (conveyor filling needles capping
machine measurement instruments etc)
The wrapping capabilities of StarCCM+ allowed to take into account the numerous components at a reasonable calculation cost
COMPUTATIONAL GEOMETRY
Numerical geometry is not always available reliable up-to-date or precise
A word on 3D Scanning prior to CFD analysishellip
Fit in a small suitcase Up and running in less than 5 minutes
No rigid set-up No particular experience from the user
Real time visualization Direct mesh output in StarCCM+ compatible STL format
COMPUTATIONAL GEOMETRY A word on portable scannershellip
Scanning demo details on the process and real-life examples of CFD analysis performed thanks to prior 3D scanning will be discussed in our 225 PM session in Pacific Room The Value of 3D Scanning Technologies as a Complementary Tool to STAR-CCM+reg for Various CFD Applications
BOUNDARY CONDITIONS
Each diffuser measured with Velocity Grid (Multiple pitot tubes)
Ventilation balancing measurements for room diffusers and return ducts
Pressure gaging in adjacent rooms for secondary airflow rates through wall openings for conveyor and the door contour
NUMERICAL METHODOLOGY
RANS ndash k-ω SST All y+ Wall Treatment Polyhedral cells
Cell count ~18M Coupled flow model 2nd order discretization
SOME RESULTS
Pressure gradient in RABS Undesirable longitudinal
velocity Remove partition Restore pressure in
capping section
Global pressure distribution
SOME RESULTS Before
After
Added panels in capping section
Transverse flow Plenum air flow
Non-sterile capping arm
RABS window with opening to cleanroom below
SOME RESULTS
Transverse flow Plenum air flow
Non-sterile capping arm
RABS window with opening to cleanroom below
Deflectors shift the air draft towards the machine floor
SOME RESULTS
Added deflectors
Impinging flow ndash accumulation table ndash focused simulation
SOME RESULTS
A focused simulation was performed with actual vials modeled and mapped boundary conditions from global simulation
Impinging flow ndash accumulation table ndash focused simulation
SOME RESULTS
A critical thickness was determined and used as a source for streamlines (backward and forward)
Simulations showed that in steady state the flow in contact with the critical thickness would entirely be evacuated through the vials shoulders
CONCLUSION
CONCLUSION
Advantages of StarCCM+ for the cleanroom analysis
1 Wrapping 2 Fast quality mesh 3 Nice visualisations for design
strategy explanations to client and regulatory agencies
Traditional smoke tests are still the
reference for accreditation even if 1 The smoke machine disturbs
the flow 2 It does not provide precise
velocities 3 The studied area is quite
small
CFD compensates those drawbacks and represents a valuable additional tool for cleanroom design
QUESTIONS
PHILIPPE B VINCENT CFD Engineer Creaform Engineering Services 5825 St-Georges Leacutevis Queacutebec G6V 4L2 Canada Phone (418) 833-4446 E-MAIL philippevincentametekcom WEB wwwcreaform3dcom
CONTACT
- Star Global 2015
- Agenda
- Our organization
- Our organization
- More than 2000 customers
- Numerical simulation Department
- Our project
- About our project
- About our project
- About our project
- Simulations
- Computational geometry
- Computational geometry
- Computational geometry
- Boundary conditions
- Numerical methodology
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Conclusion
- Conclusion
- Questions
-
AGENDA
Our Organization Our project Simulations Computational Geometry Boundary Conditions Numerical methodology
Some Results Conclusion
OUR ORGANIZATION
OUR ORGANIZATION
Engineering Services
Technologies
Metrology Services
Creaform was founded in 2002 and acquired by Ametek in 2013 Head office in Leacutevis Queacutebec Canada We develop manufacture and distribute innovative portable 3D measurement technologies and we are a leading provider of 3D engineering services 150 distributors worldwide We employ more than 385 people
Creaform helps companies to seamlessly create simulate verify and collaborate in 3D
MORE THAN 2000 CUSTOMERS
Aerospace
Consumer Products
Mass Transportation
Energy
NUMERICAL SIMULATION DEPARTMENT
bull Computational Fluid Dynamics (CFD) ndash Software StarCCM+ from CD-Adapco ndash Simulations using 3D scans ndash External aerodynamics ndash Conjugate heat transfer and thermal modeling ndash Free surface flows ndash Gas dispersion ndash Etc
bull Finite Element Analysis(FEA)
ndash Software Nastran ANSYS LS-Dyna ndash Dynamic response (Random amp Sine vibration
transient) ndash Composite analysis ndash Modal and buckling analysis ndash Contact and assembly ndash Etc
OUR PROJECT
ABOUT OUR PROJECT
bull Business Area Pharmaceutical building
services
bull Customer Project Process design installation and commissioning of a vaccine filling production line in a positive air pressure cleanroom
bull Schedule ~2 years (design to commissioning)
bull Process The RABS unit (Restricted Access Barrier) is equipped with a vials conveyor and the vaccine filling instruments The machine fills hundreds of vials per minute
RABS and vaccine filling
Cleanroom
ABOUT OUR PROJECT Detailed requirements of simulations Provide easily understood visual results of flow interactions
in the RABS to complement smoke tests Identify upward flow on critical plane 6 in above the vials
conveyor Recommend and test mitigation measures for improper
flow paths around non-sterile components of the machine
This brings up challengeshellip
bull Manage the large and detailed geometry
bull Precisely reproduce the very sensible flow in the plenum
bull Evaluate secondary air flow rates through wall openings of conveyor and cleanroom access door
Responsibilities of Creaform
CAD reproduction CFD simulations of HVAC Design improvements
ABOUT OUR PROJECT
RABS (Restricted Access Barriers)
bull Protection against contamination
bull Physical and aerodynamic barrier
bull Cleanroom Grade B
bull Inside of RABS Grade A critical zone
(glass doors with gloved access)
The extent of separation between the process and the contamination sources (ex People) determines the grade level of the protected zone
SIMULATIONS
COMPUTATIONAL GEOMETRY
Available data Cleanroom blueprints STL files of equipment
Final CFD numerical geometry Cleanroom walls and furniture Physical barrier with gloved access Control panel Machine (conveyor filling needles capping
machine measurement instruments etc)
The wrapping capabilities of StarCCM+ allowed to take into account the numerous components at a reasonable calculation cost
COMPUTATIONAL GEOMETRY
Numerical geometry is not always available reliable up-to-date or precise
A word on 3D Scanning prior to CFD analysishellip
Fit in a small suitcase Up and running in less than 5 minutes
No rigid set-up No particular experience from the user
Real time visualization Direct mesh output in StarCCM+ compatible STL format
COMPUTATIONAL GEOMETRY A word on portable scannershellip
Scanning demo details on the process and real-life examples of CFD analysis performed thanks to prior 3D scanning will be discussed in our 225 PM session in Pacific Room The Value of 3D Scanning Technologies as a Complementary Tool to STAR-CCM+reg for Various CFD Applications
BOUNDARY CONDITIONS
Each diffuser measured with Velocity Grid (Multiple pitot tubes)
Ventilation balancing measurements for room diffusers and return ducts
Pressure gaging in adjacent rooms for secondary airflow rates through wall openings for conveyor and the door contour
NUMERICAL METHODOLOGY
RANS ndash k-ω SST All y+ Wall Treatment Polyhedral cells
Cell count ~18M Coupled flow model 2nd order discretization
SOME RESULTS
Pressure gradient in RABS Undesirable longitudinal
velocity Remove partition Restore pressure in
capping section
Global pressure distribution
SOME RESULTS Before
After
Added panels in capping section
Transverse flow Plenum air flow
Non-sterile capping arm
RABS window with opening to cleanroom below
SOME RESULTS
Transverse flow Plenum air flow
Non-sterile capping arm
RABS window with opening to cleanroom below
Deflectors shift the air draft towards the machine floor
SOME RESULTS
Added deflectors
Impinging flow ndash accumulation table ndash focused simulation
SOME RESULTS
A focused simulation was performed with actual vials modeled and mapped boundary conditions from global simulation
Impinging flow ndash accumulation table ndash focused simulation
SOME RESULTS
A critical thickness was determined and used as a source for streamlines (backward and forward)
Simulations showed that in steady state the flow in contact with the critical thickness would entirely be evacuated through the vials shoulders
CONCLUSION
CONCLUSION
Advantages of StarCCM+ for the cleanroom analysis
1 Wrapping 2 Fast quality mesh 3 Nice visualisations for design
strategy explanations to client and regulatory agencies
Traditional smoke tests are still the
reference for accreditation even if 1 The smoke machine disturbs
the flow 2 It does not provide precise
velocities 3 The studied area is quite
small
CFD compensates those drawbacks and represents a valuable additional tool for cleanroom design
QUESTIONS
PHILIPPE B VINCENT CFD Engineer Creaform Engineering Services 5825 St-Georges Leacutevis Queacutebec G6V 4L2 Canada Phone (418) 833-4446 E-MAIL philippevincentametekcom WEB wwwcreaform3dcom
CONTACT
- Star Global 2015
- Agenda
- Our organization
- Our organization
- More than 2000 customers
- Numerical simulation Department
- Our project
- About our project
- About our project
- About our project
- Simulations
- Computational geometry
- Computational geometry
- Computational geometry
- Boundary conditions
- Numerical methodology
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Conclusion
- Conclusion
- Questions
-
OUR ORGANIZATION
OUR ORGANIZATION
Engineering Services
Technologies
Metrology Services
Creaform was founded in 2002 and acquired by Ametek in 2013 Head office in Leacutevis Queacutebec Canada We develop manufacture and distribute innovative portable 3D measurement technologies and we are a leading provider of 3D engineering services 150 distributors worldwide We employ more than 385 people
Creaform helps companies to seamlessly create simulate verify and collaborate in 3D
MORE THAN 2000 CUSTOMERS
Aerospace
Consumer Products
Mass Transportation
Energy
NUMERICAL SIMULATION DEPARTMENT
bull Computational Fluid Dynamics (CFD) ndash Software StarCCM+ from CD-Adapco ndash Simulations using 3D scans ndash External aerodynamics ndash Conjugate heat transfer and thermal modeling ndash Free surface flows ndash Gas dispersion ndash Etc
bull Finite Element Analysis(FEA)
ndash Software Nastran ANSYS LS-Dyna ndash Dynamic response (Random amp Sine vibration
transient) ndash Composite analysis ndash Modal and buckling analysis ndash Contact and assembly ndash Etc
OUR PROJECT
ABOUT OUR PROJECT
bull Business Area Pharmaceutical building
services
bull Customer Project Process design installation and commissioning of a vaccine filling production line in a positive air pressure cleanroom
bull Schedule ~2 years (design to commissioning)
bull Process The RABS unit (Restricted Access Barrier) is equipped with a vials conveyor and the vaccine filling instruments The machine fills hundreds of vials per minute
RABS and vaccine filling
Cleanroom
ABOUT OUR PROJECT Detailed requirements of simulations Provide easily understood visual results of flow interactions
in the RABS to complement smoke tests Identify upward flow on critical plane 6 in above the vials
conveyor Recommend and test mitigation measures for improper
flow paths around non-sterile components of the machine
This brings up challengeshellip
bull Manage the large and detailed geometry
bull Precisely reproduce the very sensible flow in the plenum
bull Evaluate secondary air flow rates through wall openings of conveyor and cleanroom access door
Responsibilities of Creaform
CAD reproduction CFD simulations of HVAC Design improvements
ABOUT OUR PROJECT
RABS (Restricted Access Barriers)
bull Protection against contamination
bull Physical and aerodynamic barrier
bull Cleanroom Grade B
bull Inside of RABS Grade A critical zone
(glass doors with gloved access)
The extent of separation between the process and the contamination sources (ex People) determines the grade level of the protected zone
SIMULATIONS
COMPUTATIONAL GEOMETRY
Available data Cleanroom blueprints STL files of equipment
Final CFD numerical geometry Cleanroom walls and furniture Physical barrier with gloved access Control panel Machine (conveyor filling needles capping
machine measurement instruments etc)
The wrapping capabilities of StarCCM+ allowed to take into account the numerous components at a reasonable calculation cost
COMPUTATIONAL GEOMETRY
Numerical geometry is not always available reliable up-to-date or precise
A word on 3D Scanning prior to CFD analysishellip
Fit in a small suitcase Up and running in less than 5 minutes
No rigid set-up No particular experience from the user
Real time visualization Direct mesh output in StarCCM+ compatible STL format
COMPUTATIONAL GEOMETRY A word on portable scannershellip
Scanning demo details on the process and real-life examples of CFD analysis performed thanks to prior 3D scanning will be discussed in our 225 PM session in Pacific Room The Value of 3D Scanning Technologies as a Complementary Tool to STAR-CCM+reg for Various CFD Applications
BOUNDARY CONDITIONS
Each diffuser measured with Velocity Grid (Multiple pitot tubes)
Ventilation balancing measurements for room diffusers and return ducts
Pressure gaging in adjacent rooms for secondary airflow rates through wall openings for conveyor and the door contour
NUMERICAL METHODOLOGY
RANS ndash k-ω SST All y+ Wall Treatment Polyhedral cells
Cell count ~18M Coupled flow model 2nd order discretization
SOME RESULTS
Pressure gradient in RABS Undesirable longitudinal
velocity Remove partition Restore pressure in
capping section
Global pressure distribution
SOME RESULTS Before
After
Added panels in capping section
Transverse flow Plenum air flow
Non-sterile capping arm
RABS window with opening to cleanroom below
SOME RESULTS
Transverse flow Plenum air flow
Non-sterile capping arm
RABS window with opening to cleanroom below
Deflectors shift the air draft towards the machine floor
SOME RESULTS
Added deflectors
Impinging flow ndash accumulation table ndash focused simulation
SOME RESULTS
A focused simulation was performed with actual vials modeled and mapped boundary conditions from global simulation
Impinging flow ndash accumulation table ndash focused simulation
SOME RESULTS
A critical thickness was determined and used as a source for streamlines (backward and forward)
Simulations showed that in steady state the flow in contact with the critical thickness would entirely be evacuated through the vials shoulders
CONCLUSION
CONCLUSION
Advantages of StarCCM+ for the cleanroom analysis
1 Wrapping 2 Fast quality mesh 3 Nice visualisations for design
strategy explanations to client and regulatory agencies
Traditional smoke tests are still the
reference for accreditation even if 1 The smoke machine disturbs
the flow 2 It does not provide precise
velocities 3 The studied area is quite
small
CFD compensates those drawbacks and represents a valuable additional tool for cleanroom design
QUESTIONS
PHILIPPE B VINCENT CFD Engineer Creaform Engineering Services 5825 St-Georges Leacutevis Queacutebec G6V 4L2 Canada Phone (418) 833-4446 E-MAIL philippevincentametekcom WEB wwwcreaform3dcom
CONTACT
- Star Global 2015
- Agenda
- Our organization
- Our organization
- More than 2000 customers
- Numerical simulation Department
- Our project
- About our project
- About our project
- About our project
- Simulations
- Computational geometry
- Computational geometry
- Computational geometry
- Boundary conditions
- Numerical methodology
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Conclusion
- Conclusion
- Questions
-
OUR ORGANIZATION
Engineering Services
Technologies
Metrology Services
Creaform was founded in 2002 and acquired by Ametek in 2013 Head office in Leacutevis Queacutebec Canada We develop manufacture and distribute innovative portable 3D measurement technologies and we are a leading provider of 3D engineering services 150 distributors worldwide We employ more than 385 people
Creaform helps companies to seamlessly create simulate verify and collaborate in 3D
MORE THAN 2000 CUSTOMERS
Aerospace
Consumer Products
Mass Transportation
Energy
NUMERICAL SIMULATION DEPARTMENT
bull Computational Fluid Dynamics (CFD) ndash Software StarCCM+ from CD-Adapco ndash Simulations using 3D scans ndash External aerodynamics ndash Conjugate heat transfer and thermal modeling ndash Free surface flows ndash Gas dispersion ndash Etc
bull Finite Element Analysis(FEA)
ndash Software Nastran ANSYS LS-Dyna ndash Dynamic response (Random amp Sine vibration
transient) ndash Composite analysis ndash Modal and buckling analysis ndash Contact and assembly ndash Etc
OUR PROJECT
ABOUT OUR PROJECT
bull Business Area Pharmaceutical building
services
bull Customer Project Process design installation and commissioning of a vaccine filling production line in a positive air pressure cleanroom
bull Schedule ~2 years (design to commissioning)
bull Process The RABS unit (Restricted Access Barrier) is equipped with a vials conveyor and the vaccine filling instruments The machine fills hundreds of vials per minute
RABS and vaccine filling
Cleanroom
ABOUT OUR PROJECT Detailed requirements of simulations Provide easily understood visual results of flow interactions
in the RABS to complement smoke tests Identify upward flow on critical plane 6 in above the vials
conveyor Recommend and test mitigation measures for improper
flow paths around non-sterile components of the machine
This brings up challengeshellip
bull Manage the large and detailed geometry
bull Precisely reproduce the very sensible flow in the plenum
bull Evaluate secondary air flow rates through wall openings of conveyor and cleanroom access door
Responsibilities of Creaform
CAD reproduction CFD simulations of HVAC Design improvements
ABOUT OUR PROJECT
RABS (Restricted Access Barriers)
bull Protection against contamination
bull Physical and aerodynamic barrier
bull Cleanroom Grade B
bull Inside of RABS Grade A critical zone
(glass doors with gloved access)
The extent of separation between the process and the contamination sources (ex People) determines the grade level of the protected zone
SIMULATIONS
COMPUTATIONAL GEOMETRY
Available data Cleanroom blueprints STL files of equipment
Final CFD numerical geometry Cleanroom walls and furniture Physical barrier with gloved access Control panel Machine (conveyor filling needles capping
machine measurement instruments etc)
The wrapping capabilities of StarCCM+ allowed to take into account the numerous components at a reasonable calculation cost
COMPUTATIONAL GEOMETRY
Numerical geometry is not always available reliable up-to-date or precise
A word on 3D Scanning prior to CFD analysishellip
Fit in a small suitcase Up and running in less than 5 minutes
No rigid set-up No particular experience from the user
Real time visualization Direct mesh output in StarCCM+ compatible STL format
COMPUTATIONAL GEOMETRY A word on portable scannershellip
Scanning demo details on the process and real-life examples of CFD analysis performed thanks to prior 3D scanning will be discussed in our 225 PM session in Pacific Room The Value of 3D Scanning Technologies as a Complementary Tool to STAR-CCM+reg for Various CFD Applications
BOUNDARY CONDITIONS
Each diffuser measured with Velocity Grid (Multiple pitot tubes)
Ventilation balancing measurements for room diffusers and return ducts
Pressure gaging in adjacent rooms for secondary airflow rates through wall openings for conveyor and the door contour
NUMERICAL METHODOLOGY
RANS ndash k-ω SST All y+ Wall Treatment Polyhedral cells
Cell count ~18M Coupled flow model 2nd order discretization
SOME RESULTS
Pressure gradient in RABS Undesirable longitudinal
velocity Remove partition Restore pressure in
capping section
Global pressure distribution
SOME RESULTS Before
After
Added panels in capping section
Transverse flow Plenum air flow
Non-sterile capping arm
RABS window with opening to cleanroom below
SOME RESULTS
Transverse flow Plenum air flow
Non-sterile capping arm
RABS window with opening to cleanroom below
Deflectors shift the air draft towards the machine floor
SOME RESULTS
Added deflectors
Impinging flow ndash accumulation table ndash focused simulation
SOME RESULTS
A focused simulation was performed with actual vials modeled and mapped boundary conditions from global simulation
Impinging flow ndash accumulation table ndash focused simulation
SOME RESULTS
A critical thickness was determined and used as a source for streamlines (backward and forward)
Simulations showed that in steady state the flow in contact with the critical thickness would entirely be evacuated through the vials shoulders
CONCLUSION
CONCLUSION
Advantages of StarCCM+ for the cleanroom analysis
1 Wrapping 2 Fast quality mesh 3 Nice visualisations for design
strategy explanations to client and regulatory agencies
Traditional smoke tests are still the
reference for accreditation even if 1 The smoke machine disturbs
the flow 2 It does not provide precise
velocities 3 The studied area is quite
small
CFD compensates those drawbacks and represents a valuable additional tool for cleanroom design
QUESTIONS
PHILIPPE B VINCENT CFD Engineer Creaform Engineering Services 5825 St-Georges Leacutevis Queacutebec G6V 4L2 Canada Phone (418) 833-4446 E-MAIL philippevincentametekcom WEB wwwcreaform3dcom
CONTACT
- Star Global 2015
- Agenda
- Our organization
- Our organization
- More than 2000 customers
- Numerical simulation Department
- Our project
- About our project
- About our project
- About our project
- Simulations
- Computational geometry
- Computational geometry
- Computational geometry
- Boundary conditions
- Numerical methodology
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Conclusion
- Conclusion
- Questions
-
MORE THAN 2000 CUSTOMERS
Aerospace
Consumer Products
Mass Transportation
Energy
NUMERICAL SIMULATION DEPARTMENT
bull Computational Fluid Dynamics (CFD) ndash Software StarCCM+ from CD-Adapco ndash Simulations using 3D scans ndash External aerodynamics ndash Conjugate heat transfer and thermal modeling ndash Free surface flows ndash Gas dispersion ndash Etc
bull Finite Element Analysis(FEA)
ndash Software Nastran ANSYS LS-Dyna ndash Dynamic response (Random amp Sine vibration
transient) ndash Composite analysis ndash Modal and buckling analysis ndash Contact and assembly ndash Etc
OUR PROJECT
ABOUT OUR PROJECT
bull Business Area Pharmaceutical building
services
bull Customer Project Process design installation and commissioning of a vaccine filling production line in a positive air pressure cleanroom
bull Schedule ~2 years (design to commissioning)
bull Process The RABS unit (Restricted Access Barrier) is equipped with a vials conveyor and the vaccine filling instruments The machine fills hundreds of vials per minute
RABS and vaccine filling
Cleanroom
ABOUT OUR PROJECT Detailed requirements of simulations Provide easily understood visual results of flow interactions
in the RABS to complement smoke tests Identify upward flow on critical plane 6 in above the vials
conveyor Recommend and test mitigation measures for improper
flow paths around non-sterile components of the machine
This brings up challengeshellip
bull Manage the large and detailed geometry
bull Precisely reproduce the very sensible flow in the plenum
bull Evaluate secondary air flow rates through wall openings of conveyor and cleanroom access door
Responsibilities of Creaform
CAD reproduction CFD simulations of HVAC Design improvements
ABOUT OUR PROJECT
RABS (Restricted Access Barriers)
bull Protection against contamination
bull Physical and aerodynamic barrier
bull Cleanroom Grade B
bull Inside of RABS Grade A critical zone
(glass doors with gloved access)
The extent of separation between the process and the contamination sources (ex People) determines the grade level of the protected zone
SIMULATIONS
COMPUTATIONAL GEOMETRY
Available data Cleanroom blueprints STL files of equipment
Final CFD numerical geometry Cleanroom walls and furniture Physical barrier with gloved access Control panel Machine (conveyor filling needles capping
machine measurement instruments etc)
The wrapping capabilities of StarCCM+ allowed to take into account the numerous components at a reasonable calculation cost
COMPUTATIONAL GEOMETRY
Numerical geometry is not always available reliable up-to-date or precise
A word on 3D Scanning prior to CFD analysishellip
Fit in a small suitcase Up and running in less than 5 minutes
No rigid set-up No particular experience from the user
Real time visualization Direct mesh output in StarCCM+ compatible STL format
COMPUTATIONAL GEOMETRY A word on portable scannershellip
Scanning demo details on the process and real-life examples of CFD analysis performed thanks to prior 3D scanning will be discussed in our 225 PM session in Pacific Room The Value of 3D Scanning Technologies as a Complementary Tool to STAR-CCM+reg for Various CFD Applications
BOUNDARY CONDITIONS
Each diffuser measured with Velocity Grid (Multiple pitot tubes)
Ventilation balancing measurements for room diffusers and return ducts
Pressure gaging in adjacent rooms for secondary airflow rates through wall openings for conveyor and the door contour
NUMERICAL METHODOLOGY
RANS ndash k-ω SST All y+ Wall Treatment Polyhedral cells
Cell count ~18M Coupled flow model 2nd order discretization
SOME RESULTS
Pressure gradient in RABS Undesirable longitudinal
velocity Remove partition Restore pressure in
capping section
Global pressure distribution
SOME RESULTS Before
After
Added panels in capping section
Transverse flow Plenum air flow
Non-sterile capping arm
RABS window with opening to cleanroom below
SOME RESULTS
Transverse flow Plenum air flow
Non-sterile capping arm
RABS window with opening to cleanroom below
Deflectors shift the air draft towards the machine floor
SOME RESULTS
Added deflectors
Impinging flow ndash accumulation table ndash focused simulation
SOME RESULTS
A focused simulation was performed with actual vials modeled and mapped boundary conditions from global simulation
Impinging flow ndash accumulation table ndash focused simulation
SOME RESULTS
A critical thickness was determined and used as a source for streamlines (backward and forward)
Simulations showed that in steady state the flow in contact with the critical thickness would entirely be evacuated through the vials shoulders
CONCLUSION
CONCLUSION
Advantages of StarCCM+ for the cleanroom analysis
1 Wrapping 2 Fast quality mesh 3 Nice visualisations for design
strategy explanations to client and regulatory agencies
Traditional smoke tests are still the
reference for accreditation even if 1 The smoke machine disturbs
the flow 2 It does not provide precise
velocities 3 The studied area is quite
small
CFD compensates those drawbacks and represents a valuable additional tool for cleanroom design
QUESTIONS
PHILIPPE B VINCENT CFD Engineer Creaform Engineering Services 5825 St-Georges Leacutevis Queacutebec G6V 4L2 Canada Phone (418) 833-4446 E-MAIL philippevincentametekcom WEB wwwcreaform3dcom
CONTACT
- Star Global 2015
- Agenda
- Our organization
- Our organization
- More than 2000 customers
- Numerical simulation Department
- Our project
- About our project
- About our project
- About our project
- Simulations
- Computational geometry
- Computational geometry
- Computational geometry
- Boundary conditions
- Numerical methodology
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Conclusion
- Conclusion
- Questions
-
NUMERICAL SIMULATION DEPARTMENT
bull Computational Fluid Dynamics (CFD) ndash Software StarCCM+ from CD-Adapco ndash Simulations using 3D scans ndash External aerodynamics ndash Conjugate heat transfer and thermal modeling ndash Free surface flows ndash Gas dispersion ndash Etc
bull Finite Element Analysis(FEA)
ndash Software Nastran ANSYS LS-Dyna ndash Dynamic response (Random amp Sine vibration
transient) ndash Composite analysis ndash Modal and buckling analysis ndash Contact and assembly ndash Etc
OUR PROJECT
ABOUT OUR PROJECT
bull Business Area Pharmaceutical building
services
bull Customer Project Process design installation and commissioning of a vaccine filling production line in a positive air pressure cleanroom
bull Schedule ~2 years (design to commissioning)
bull Process The RABS unit (Restricted Access Barrier) is equipped with a vials conveyor and the vaccine filling instruments The machine fills hundreds of vials per minute
RABS and vaccine filling
Cleanroom
ABOUT OUR PROJECT Detailed requirements of simulations Provide easily understood visual results of flow interactions
in the RABS to complement smoke tests Identify upward flow on critical plane 6 in above the vials
conveyor Recommend and test mitigation measures for improper
flow paths around non-sterile components of the machine
This brings up challengeshellip
bull Manage the large and detailed geometry
bull Precisely reproduce the very sensible flow in the plenum
bull Evaluate secondary air flow rates through wall openings of conveyor and cleanroom access door
Responsibilities of Creaform
CAD reproduction CFD simulations of HVAC Design improvements
ABOUT OUR PROJECT
RABS (Restricted Access Barriers)
bull Protection against contamination
bull Physical and aerodynamic barrier
bull Cleanroom Grade B
bull Inside of RABS Grade A critical zone
(glass doors with gloved access)
The extent of separation between the process and the contamination sources (ex People) determines the grade level of the protected zone
SIMULATIONS
COMPUTATIONAL GEOMETRY
Available data Cleanroom blueprints STL files of equipment
Final CFD numerical geometry Cleanroom walls and furniture Physical barrier with gloved access Control panel Machine (conveyor filling needles capping
machine measurement instruments etc)
The wrapping capabilities of StarCCM+ allowed to take into account the numerous components at a reasonable calculation cost
COMPUTATIONAL GEOMETRY
Numerical geometry is not always available reliable up-to-date or precise
A word on 3D Scanning prior to CFD analysishellip
Fit in a small suitcase Up and running in less than 5 minutes
No rigid set-up No particular experience from the user
Real time visualization Direct mesh output in StarCCM+ compatible STL format
COMPUTATIONAL GEOMETRY A word on portable scannershellip
Scanning demo details on the process and real-life examples of CFD analysis performed thanks to prior 3D scanning will be discussed in our 225 PM session in Pacific Room The Value of 3D Scanning Technologies as a Complementary Tool to STAR-CCM+reg for Various CFD Applications
BOUNDARY CONDITIONS
Each diffuser measured with Velocity Grid (Multiple pitot tubes)
Ventilation balancing measurements for room diffusers and return ducts
Pressure gaging in adjacent rooms for secondary airflow rates through wall openings for conveyor and the door contour
NUMERICAL METHODOLOGY
RANS ndash k-ω SST All y+ Wall Treatment Polyhedral cells
Cell count ~18M Coupled flow model 2nd order discretization
SOME RESULTS
Pressure gradient in RABS Undesirable longitudinal
velocity Remove partition Restore pressure in
capping section
Global pressure distribution
SOME RESULTS Before
After
Added panels in capping section
Transverse flow Plenum air flow
Non-sterile capping arm
RABS window with opening to cleanroom below
SOME RESULTS
Transverse flow Plenum air flow
Non-sterile capping arm
RABS window with opening to cleanroom below
Deflectors shift the air draft towards the machine floor
SOME RESULTS
Added deflectors
Impinging flow ndash accumulation table ndash focused simulation
SOME RESULTS
A focused simulation was performed with actual vials modeled and mapped boundary conditions from global simulation
Impinging flow ndash accumulation table ndash focused simulation
SOME RESULTS
A critical thickness was determined and used as a source for streamlines (backward and forward)
Simulations showed that in steady state the flow in contact with the critical thickness would entirely be evacuated through the vials shoulders
CONCLUSION
CONCLUSION
Advantages of StarCCM+ for the cleanroom analysis
1 Wrapping 2 Fast quality mesh 3 Nice visualisations for design
strategy explanations to client and regulatory agencies
Traditional smoke tests are still the
reference for accreditation even if 1 The smoke machine disturbs
the flow 2 It does not provide precise
velocities 3 The studied area is quite
small
CFD compensates those drawbacks and represents a valuable additional tool for cleanroom design
QUESTIONS
PHILIPPE B VINCENT CFD Engineer Creaform Engineering Services 5825 St-Georges Leacutevis Queacutebec G6V 4L2 Canada Phone (418) 833-4446 E-MAIL philippevincentametekcom WEB wwwcreaform3dcom
CONTACT
- Star Global 2015
- Agenda
- Our organization
- Our organization
- More than 2000 customers
- Numerical simulation Department
- Our project
- About our project
- About our project
- About our project
- Simulations
- Computational geometry
- Computational geometry
- Computational geometry
- Boundary conditions
- Numerical methodology
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Conclusion
- Conclusion
- Questions
-
OUR PROJECT
ABOUT OUR PROJECT
bull Business Area Pharmaceutical building
services
bull Customer Project Process design installation and commissioning of a vaccine filling production line in a positive air pressure cleanroom
bull Schedule ~2 years (design to commissioning)
bull Process The RABS unit (Restricted Access Barrier) is equipped with a vials conveyor and the vaccine filling instruments The machine fills hundreds of vials per minute
RABS and vaccine filling
Cleanroom
ABOUT OUR PROJECT Detailed requirements of simulations Provide easily understood visual results of flow interactions
in the RABS to complement smoke tests Identify upward flow on critical plane 6 in above the vials
conveyor Recommend and test mitigation measures for improper
flow paths around non-sterile components of the machine
This brings up challengeshellip
bull Manage the large and detailed geometry
bull Precisely reproduce the very sensible flow in the plenum
bull Evaluate secondary air flow rates through wall openings of conveyor and cleanroom access door
Responsibilities of Creaform
CAD reproduction CFD simulations of HVAC Design improvements
ABOUT OUR PROJECT
RABS (Restricted Access Barriers)
bull Protection against contamination
bull Physical and aerodynamic barrier
bull Cleanroom Grade B
bull Inside of RABS Grade A critical zone
(glass doors with gloved access)
The extent of separation between the process and the contamination sources (ex People) determines the grade level of the protected zone
SIMULATIONS
COMPUTATIONAL GEOMETRY
Available data Cleanroom blueprints STL files of equipment
Final CFD numerical geometry Cleanroom walls and furniture Physical barrier with gloved access Control panel Machine (conveyor filling needles capping
machine measurement instruments etc)
The wrapping capabilities of StarCCM+ allowed to take into account the numerous components at a reasonable calculation cost
COMPUTATIONAL GEOMETRY
Numerical geometry is not always available reliable up-to-date or precise
A word on 3D Scanning prior to CFD analysishellip
Fit in a small suitcase Up and running in less than 5 minutes
No rigid set-up No particular experience from the user
Real time visualization Direct mesh output in StarCCM+ compatible STL format
COMPUTATIONAL GEOMETRY A word on portable scannershellip
Scanning demo details on the process and real-life examples of CFD analysis performed thanks to prior 3D scanning will be discussed in our 225 PM session in Pacific Room The Value of 3D Scanning Technologies as a Complementary Tool to STAR-CCM+reg for Various CFD Applications
BOUNDARY CONDITIONS
Each diffuser measured with Velocity Grid (Multiple pitot tubes)
Ventilation balancing measurements for room diffusers and return ducts
Pressure gaging in adjacent rooms for secondary airflow rates through wall openings for conveyor and the door contour
NUMERICAL METHODOLOGY
RANS ndash k-ω SST All y+ Wall Treatment Polyhedral cells
Cell count ~18M Coupled flow model 2nd order discretization
SOME RESULTS
Pressure gradient in RABS Undesirable longitudinal
velocity Remove partition Restore pressure in
capping section
Global pressure distribution
SOME RESULTS Before
After
Added panels in capping section
Transverse flow Plenum air flow
Non-sterile capping arm
RABS window with opening to cleanroom below
SOME RESULTS
Transverse flow Plenum air flow
Non-sterile capping arm
RABS window with opening to cleanroom below
Deflectors shift the air draft towards the machine floor
SOME RESULTS
Added deflectors
Impinging flow ndash accumulation table ndash focused simulation
SOME RESULTS
A focused simulation was performed with actual vials modeled and mapped boundary conditions from global simulation
Impinging flow ndash accumulation table ndash focused simulation
SOME RESULTS
A critical thickness was determined and used as a source for streamlines (backward and forward)
Simulations showed that in steady state the flow in contact with the critical thickness would entirely be evacuated through the vials shoulders
CONCLUSION
CONCLUSION
Advantages of StarCCM+ for the cleanroom analysis
1 Wrapping 2 Fast quality mesh 3 Nice visualisations for design
strategy explanations to client and regulatory agencies
Traditional smoke tests are still the
reference for accreditation even if 1 The smoke machine disturbs
the flow 2 It does not provide precise
velocities 3 The studied area is quite
small
CFD compensates those drawbacks and represents a valuable additional tool for cleanroom design
QUESTIONS
PHILIPPE B VINCENT CFD Engineer Creaform Engineering Services 5825 St-Georges Leacutevis Queacutebec G6V 4L2 Canada Phone (418) 833-4446 E-MAIL philippevincentametekcom WEB wwwcreaform3dcom
CONTACT
- Star Global 2015
- Agenda
- Our organization
- Our organization
- More than 2000 customers
- Numerical simulation Department
- Our project
- About our project
- About our project
- About our project
- Simulations
- Computational geometry
- Computational geometry
- Computational geometry
- Boundary conditions
- Numerical methodology
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Conclusion
- Conclusion
- Questions
-
ABOUT OUR PROJECT
bull Business Area Pharmaceutical building
services
bull Customer Project Process design installation and commissioning of a vaccine filling production line in a positive air pressure cleanroom
bull Schedule ~2 years (design to commissioning)
bull Process The RABS unit (Restricted Access Barrier) is equipped with a vials conveyor and the vaccine filling instruments The machine fills hundreds of vials per minute
RABS and vaccine filling
Cleanroom
ABOUT OUR PROJECT Detailed requirements of simulations Provide easily understood visual results of flow interactions
in the RABS to complement smoke tests Identify upward flow on critical plane 6 in above the vials
conveyor Recommend and test mitigation measures for improper
flow paths around non-sterile components of the machine
This brings up challengeshellip
bull Manage the large and detailed geometry
bull Precisely reproduce the very sensible flow in the plenum
bull Evaluate secondary air flow rates through wall openings of conveyor and cleanroom access door
Responsibilities of Creaform
CAD reproduction CFD simulations of HVAC Design improvements
ABOUT OUR PROJECT
RABS (Restricted Access Barriers)
bull Protection against contamination
bull Physical and aerodynamic barrier
bull Cleanroom Grade B
bull Inside of RABS Grade A critical zone
(glass doors with gloved access)
The extent of separation between the process and the contamination sources (ex People) determines the grade level of the protected zone
SIMULATIONS
COMPUTATIONAL GEOMETRY
Available data Cleanroom blueprints STL files of equipment
Final CFD numerical geometry Cleanroom walls and furniture Physical barrier with gloved access Control panel Machine (conveyor filling needles capping
machine measurement instruments etc)
The wrapping capabilities of StarCCM+ allowed to take into account the numerous components at a reasonable calculation cost
COMPUTATIONAL GEOMETRY
Numerical geometry is not always available reliable up-to-date or precise
A word on 3D Scanning prior to CFD analysishellip
Fit in a small suitcase Up and running in less than 5 minutes
No rigid set-up No particular experience from the user
Real time visualization Direct mesh output in StarCCM+ compatible STL format
COMPUTATIONAL GEOMETRY A word on portable scannershellip
Scanning demo details on the process and real-life examples of CFD analysis performed thanks to prior 3D scanning will be discussed in our 225 PM session in Pacific Room The Value of 3D Scanning Technologies as a Complementary Tool to STAR-CCM+reg for Various CFD Applications
BOUNDARY CONDITIONS
Each diffuser measured with Velocity Grid (Multiple pitot tubes)
Ventilation balancing measurements for room diffusers and return ducts
Pressure gaging in adjacent rooms for secondary airflow rates through wall openings for conveyor and the door contour
NUMERICAL METHODOLOGY
RANS ndash k-ω SST All y+ Wall Treatment Polyhedral cells
Cell count ~18M Coupled flow model 2nd order discretization
SOME RESULTS
Pressure gradient in RABS Undesirable longitudinal
velocity Remove partition Restore pressure in
capping section
Global pressure distribution
SOME RESULTS Before
After
Added panels in capping section
Transverse flow Plenum air flow
Non-sterile capping arm
RABS window with opening to cleanroom below
SOME RESULTS
Transverse flow Plenum air flow
Non-sterile capping arm
RABS window with opening to cleanroom below
Deflectors shift the air draft towards the machine floor
SOME RESULTS
Added deflectors
Impinging flow ndash accumulation table ndash focused simulation
SOME RESULTS
A focused simulation was performed with actual vials modeled and mapped boundary conditions from global simulation
Impinging flow ndash accumulation table ndash focused simulation
SOME RESULTS
A critical thickness was determined and used as a source for streamlines (backward and forward)
Simulations showed that in steady state the flow in contact with the critical thickness would entirely be evacuated through the vials shoulders
CONCLUSION
CONCLUSION
Advantages of StarCCM+ for the cleanroom analysis
1 Wrapping 2 Fast quality mesh 3 Nice visualisations for design
strategy explanations to client and regulatory agencies
Traditional smoke tests are still the
reference for accreditation even if 1 The smoke machine disturbs
the flow 2 It does not provide precise
velocities 3 The studied area is quite
small
CFD compensates those drawbacks and represents a valuable additional tool for cleanroom design
QUESTIONS
PHILIPPE B VINCENT CFD Engineer Creaform Engineering Services 5825 St-Georges Leacutevis Queacutebec G6V 4L2 Canada Phone (418) 833-4446 E-MAIL philippevincentametekcom WEB wwwcreaform3dcom
CONTACT
- Star Global 2015
- Agenda
- Our organization
- Our organization
- More than 2000 customers
- Numerical simulation Department
- Our project
- About our project
- About our project
- About our project
- Simulations
- Computational geometry
- Computational geometry
- Computational geometry
- Boundary conditions
- Numerical methodology
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Conclusion
- Conclusion
- Questions
-
ABOUT OUR PROJECT Detailed requirements of simulations Provide easily understood visual results of flow interactions
in the RABS to complement smoke tests Identify upward flow on critical plane 6 in above the vials
conveyor Recommend and test mitigation measures for improper
flow paths around non-sterile components of the machine
This brings up challengeshellip
bull Manage the large and detailed geometry
bull Precisely reproduce the very sensible flow in the plenum
bull Evaluate secondary air flow rates through wall openings of conveyor and cleanroom access door
Responsibilities of Creaform
CAD reproduction CFD simulations of HVAC Design improvements
ABOUT OUR PROJECT
RABS (Restricted Access Barriers)
bull Protection against contamination
bull Physical and aerodynamic barrier
bull Cleanroom Grade B
bull Inside of RABS Grade A critical zone
(glass doors with gloved access)
The extent of separation between the process and the contamination sources (ex People) determines the grade level of the protected zone
SIMULATIONS
COMPUTATIONAL GEOMETRY
Available data Cleanroom blueprints STL files of equipment
Final CFD numerical geometry Cleanroom walls and furniture Physical barrier with gloved access Control panel Machine (conveyor filling needles capping
machine measurement instruments etc)
The wrapping capabilities of StarCCM+ allowed to take into account the numerous components at a reasonable calculation cost
COMPUTATIONAL GEOMETRY
Numerical geometry is not always available reliable up-to-date or precise
A word on 3D Scanning prior to CFD analysishellip
Fit in a small suitcase Up and running in less than 5 minutes
No rigid set-up No particular experience from the user
Real time visualization Direct mesh output in StarCCM+ compatible STL format
COMPUTATIONAL GEOMETRY A word on portable scannershellip
Scanning demo details on the process and real-life examples of CFD analysis performed thanks to prior 3D scanning will be discussed in our 225 PM session in Pacific Room The Value of 3D Scanning Technologies as a Complementary Tool to STAR-CCM+reg for Various CFD Applications
BOUNDARY CONDITIONS
Each diffuser measured with Velocity Grid (Multiple pitot tubes)
Ventilation balancing measurements for room diffusers and return ducts
Pressure gaging in adjacent rooms for secondary airflow rates through wall openings for conveyor and the door contour
NUMERICAL METHODOLOGY
RANS ndash k-ω SST All y+ Wall Treatment Polyhedral cells
Cell count ~18M Coupled flow model 2nd order discretization
SOME RESULTS
Pressure gradient in RABS Undesirable longitudinal
velocity Remove partition Restore pressure in
capping section
Global pressure distribution
SOME RESULTS Before
After
Added panels in capping section
Transverse flow Plenum air flow
Non-sterile capping arm
RABS window with opening to cleanroom below
SOME RESULTS
Transverse flow Plenum air flow
Non-sterile capping arm
RABS window with opening to cleanroom below
Deflectors shift the air draft towards the machine floor
SOME RESULTS
Added deflectors
Impinging flow ndash accumulation table ndash focused simulation
SOME RESULTS
A focused simulation was performed with actual vials modeled and mapped boundary conditions from global simulation
Impinging flow ndash accumulation table ndash focused simulation
SOME RESULTS
A critical thickness was determined and used as a source for streamlines (backward and forward)
Simulations showed that in steady state the flow in contact with the critical thickness would entirely be evacuated through the vials shoulders
CONCLUSION
CONCLUSION
Advantages of StarCCM+ for the cleanroom analysis
1 Wrapping 2 Fast quality mesh 3 Nice visualisations for design
strategy explanations to client and regulatory agencies
Traditional smoke tests are still the
reference for accreditation even if 1 The smoke machine disturbs
the flow 2 It does not provide precise
velocities 3 The studied area is quite
small
CFD compensates those drawbacks and represents a valuable additional tool for cleanroom design
QUESTIONS
PHILIPPE B VINCENT CFD Engineer Creaform Engineering Services 5825 St-Georges Leacutevis Queacutebec G6V 4L2 Canada Phone (418) 833-4446 E-MAIL philippevincentametekcom WEB wwwcreaform3dcom
CONTACT
- Star Global 2015
- Agenda
- Our organization
- Our organization
- More than 2000 customers
- Numerical simulation Department
- Our project
- About our project
- About our project
- About our project
- Simulations
- Computational geometry
- Computational geometry
- Computational geometry
- Boundary conditions
- Numerical methodology
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Conclusion
- Conclusion
- Questions
-
ABOUT OUR PROJECT
RABS (Restricted Access Barriers)
bull Protection against contamination
bull Physical and aerodynamic barrier
bull Cleanroom Grade B
bull Inside of RABS Grade A critical zone
(glass doors with gloved access)
The extent of separation between the process and the contamination sources (ex People) determines the grade level of the protected zone
SIMULATIONS
COMPUTATIONAL GEOMETRY
Available data Cleanroom blueprints STL files of equipment
Final CFD numerical geometry Cleanroom walls and furniture Physical barrier with gloved access Control panel Machine (conveyor filling needles capping
machine measurement instruments etc)
The wrapping capabilities of StarCCM+ allowed to take into account the numerous components at a reasonable calculation cost
COMPUTATIONAL GEOMETRY
Numerical geometry is not always available reliable up-to-date or precise
A word on 3D Scanning prior to CFD analysishellip
Fit in a small suitcase Up and running in less than 5 minutes
No rigid set-up No particular experience from the user
Real time visualization Direct mesh output in StarCCM+ compatible STL format
COMPUTATIONAL GEOMETRY A word on portable scannershellip
Scanning demo details on the process and real-life examples of CFD analysis performed thanks to prior 3D scanning will be discussed in our 225 PM session in Pacific Room The Value of 3D Scanning Technologies as a Complementary Tool to STAR-CCM+reg for Various CFD Applications
BOUNDARY CONDITIONS
Each diffuser measured with Velocity Grid (Multiple pitot tubes)
Ventilation balancing measurements for room diffusers and return ducts
Pressure gaging in adjacent rooms for secondary airflow rates through wall openings for conveyor and the door contour
NUMERICAL METHODOLOGY
RANS ndash k-ω SST All y+ Wall Treatment Polyhedral cells
Cell count ~18M Coupled flow model 2nd order discretization
SOME RESULTS
Pressure gradient in RABS Undesirable longitudinal
velocity Remove partition Restore pressure in
capping section
Global pressure distribution
SOME RESULTS Before
After
Added panels in capping section
Transverse flow Plenum air flow
Non-sterile capping arm
RABS window with opening to cleanroom below
SOME RESULTS
Transverse flow Plenum air flow
Non-sterile capping arm
RABS window with opening to cleanroom below
Deflectors shift the air draft towards the machine floor
SOME RESULTS
Added deflectors
Impinging flow ndash accumulation table ndash focused simulation
SOME RESULTS
A focused simulation was performed with actual vials modeled and mapped boundary conditions from global simulation
Impinging flow ndash accumulation table ndash focused simulation
SOME RESULTS
A critical thickness was determined and used as a source for streamlines (backward and forward)
Simulations showed that in steady state the flow in contact with the critical thickness would entirely be evacuated through the vials shoulders
CONCLUSION
CONCLUSION
Advantages of StarCCM+ for the cleanroom analysis
1 Wrapping 2 Fast quality mesh 3 Nice visualisations for design
strategy explanations to client and regulatory agencies
Traditional smoke tests are still the
reference for accreditation even if 1 The smoke machine disturbs
the flow 2 It does not provide precise
velocities 3 The studied area is quite
small
CFD compensates those drawbacks and represents a valuable additional tool for cleanroom design
QUESTIONS
PHILIPPE B VINCENT CFD Engineer Creaform Engineering Services 5825 St-Georges Leacutevis Queacutebec G6V 4L2 Canada Phone (418) 833-4446 E-MAIL philippevincentametekcom WEB wwwcreaform3dcom
CONTACT
- Star Global 2015
- Agenda
- Our organization
- Our organization
- More than 2000 customers
- Numerical simulation Department
- Our project
- About our project
- About our project
- About our project
- Simulations
- Computational geometry
- Computational geometry
- Computational geometry
- Boundary conditions
- Numerical methodology
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Conclusion
- Conclusion
- Questions
-
SIMULATIONS
COMPUTATIONAL GEOMETRY
Available data Cleanroom blueprints STL files of equipment
Final CFD numerical geometry Cleanroom walls and furniture Physical barrier with gloved access Control panel Machine (conveyor filling needles capping
machine measurement instruments etc)
The wrapping capabilities of StarCCM+ allowed to take into account the numerous components at a reasonable calculation cost
COMPUTATIONAL GEOMETRY
Numerical geometry is not always available reliable up-to-date or precise
A word on 3D Scanning prior to CFD analysishellip
Fit in a small suitcase Up and running in less than 5 minutes
No rigid set-up No particular experience from the user
Real time visualization Direct mesh output in StarCCM+ compatible STL format
COMPUTATIONAL GEOMETRY A word on portable scannershellip
Scanning demo details on the process and real-life examples of CFD analysis performed thanks to prior 3D scanning will be discussed in our 225 PM session in Pacific Room The Value of 3D Scanning Technologies as a Complementary Tool to STAR-CCM+reg for Various CFD Applications
BOUNDARY CONDITIONS
Each diffuser measured with Velocity Grid (Multiple pitot tubes)
Ventilation balancing measurements for room diffusers and return ducts
Pressure gaging in adjacent rooms for secondary airflow rates through wall openings for conveyor and the door contour
NUMERICAL METHODOLOGY
RANS ndash k-ω SST All y+ Wall Treatment Polyhedral cells
Cell count ~18M Coupled flow model 2nd order discretization
SOME RESULTS
Pressure gradient in RABS Undesirable longitudinal
velocity Remove partition Restore pressure in
capping section
Global pressure distribution
SOME RESULTS Before
After
Added panels in capping section
Transverse flow Plenum air flow
Non-sterile capping arm
RABS window with opening to cleanroom below
SOME RESULTS
Transverse flow Plenum air flow
Non-sterile capping arm
RABS window with opening to cleanroom below
Deflectors shift the air draft towards the machine floor
SOME RESULTS
Added deflectors
Impinging flow ndash accumulation table ndash focused simulation
SOME RESULTS
A focused simulation was performed with actual vials modeled and mapped boundary conditions from global simulation
Impinging flow ndash accumulation table ndash focused simulation
SOME RESULTS
A critical thickness was determined and used as a source for streamlines (backward and forward)
Simulations showed that in steady state the flow in contact with the critical thickness would entirely be evacuated through the vials shoulders
CONCLUSION
CONCLUSION
Advantages of StarCCM+ for the cleanroom analysis
1 Wrapping 2 Fast quality mesh 3 Nice visualisations for design
strategy explanations to client and regulatory agencies
Traditional smoke tests are still the
reference for accreditation even if 1 The smoke machine disturbs
the flow 2 It does not provide precise
velocities 3 The studied area is quite
small
CFD compensates those drawbacks and represents a valuable additional tool for cleanroom design
QUESTIONS
PHILIPPE B VINCENT CFD Engineer Creaform Engineering Services 5825 St-Georges Leacutevis Queacutebec G6V 4L2 Canada Phone (418) 833-4446 E-MAIL philippevincentametekcom WEB wwwcreaform3dcom
CONTACT
- Star Global 2015
- Agenda
- Our organization
- Our organization
- More than 2000 customers
- Numerical simulation Department
- Our project
- About our project
- About our project
- About our project
- Simulations
- Computational geometry
- Computational geometry
- Computational geometry
- Boundary conditions
- Numerical methodology
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Conclusion
- Conclusion
- Questions
-
COMPUTATIONAL GEOMETRY
Available data Cleanroom blueprints STL files of equipment
Final CFD numerical geometry Cleanroom walls and furniture Physical barrier with gloved access Control panel Machine (conveyor filling needles capping
machine measurement instruments etc)
The wrapping capabilities of StarCCM+ allowed to take into account the numerous components at a reasonable calculation cost
COMPUTATIONAL GEOMETRY
Numerical geometry is not always available reliable up-to-date or precise
A word on 3D Scanning prior to CFD analysishellip
Fit in a small suitcase Up and running in less than 5 minutes
No rigid set-up No particular experience from the user
Real time visualization Direct mesh output in StarCCM+ compatible STL format
COMPUTATIONAL GEOMETRY A word on portable scannershellip
Scanning demo details on the process and real-life examples of CFD analysis performed thanks to prior 3D scanning will be discussed in our 225 PM session in Pacific Room The Value of 3D Scanning Technologies as a Complementary Tool to STAR-CCM+reg for Various CFD Applications
BOUNDARY CONDITIONS
Each diffuser measured with Velocity Grid (Multiple pitot tubes)
Ventilation balancing measurements for room diffusers and return ducts
Pressure gaging in adjacent rooms for secondary airflow rates through wall openings for conveyor and the door contour
NUMERICAL METHODOLOGY
RANS ndash k-ω SST All y+ Wall Treatment Polyhedral cells
Cell count ~18M Coupled flow model 2nd order discretization
SOME RESULTS
Pressure gradient in RABS Undesirable longitudinal
velocity Remove partition Restore pressure in
capping section
Global pressure distribution
SOME RESULTS Before
After
Added panels in capping section
Transverse flow Plenum air flow
Non-sterile capping arm
RABS window with opening to cleanroom below
SOME RESULTS
Transverse flow Plenum air flow
Non-sterile capping arm
RABS window with opening to cleanroom below
Deflectors shift the air draft towards the machine floor
SOME RESULTS
Added deflectors
Impinging flow ndash accumulation table ndash focused simulation
SOME RESULTS
A focused simulation was performed with actual vials modeled and mapped boundary conditions from global simulation
Impinging flow ndash accumulation table ndash focused simulation
SOME RESULTS
A critical thickness was determined and used as a source for streamlines (backward and forward)
Simulations showed that in steady state the flow in contact with the critical thickness would entirely be evacuated through the vials shoulders
CONCLUSION
CONCLUSION
Advantages of StarCCM+ for the cleanroom analysis
1 Wrapping 2 Fast quality mesh 3 Nice visualisations for design
strategy explanations to client and regulatory agencies
Traditional smoke tests are still the
reference for accreditation even if 1 The smoke machine disturbs
the flow 2 It does not provide precise
velocities 3 The studied area is quite
small
CFD compensates those drawbacks and represents a valuable additional tool for cleanroom design
QUESTIONS
PHILIPPE B VINCENT CFD Engineer Creaform Engineering Services 5825 St-Georges Leacutevis Queacutebec G6V 4L2 Canada Phone (418) 833-4446 E-MAIL philippevincentametekcom WEB wwwcreaform3dcom
CONTACT
- Star Global 2015
- Agenda
- Our organization
- Our organization
- More than 2000 customers
- Numerical simulation Department
- Our project
- About our project
- About our project
- About our project
- Simulations
- Computational geometry
- Computational geometry
- Computational geometry
- Boundary conditions
- Numerical methodology
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Conclusion
- Conclusion
- Questions
-
COMPUTATIONAL GEOMETRY
Numerical geometry is not always available reliable up-to-date or precise
A word on 3D Scanning prior to CFD analysishellip
Fit in a small suitcase Up and running in less than 5 minutes
No rigid set-up No particular experience from the user
Real time visualization Direct mesh output in StarCCM+ compatible STL format
COMPUTATIONAL GEOMETRY A word on portable scannershellip
Scanning demo details on the process and real-life examples of CFD analysis performed thanks to prior 3D scanning will be discussed in our 225 PM session in Pacific Room The Value of 3D Scanning Technologies as a Complementary Tool to STAR-CCM+reg for Various CFD Applications
BOUNDARY CONDITIONS
Each diffuser measured with Velocity Grid (Multiple pitot tubes)
Ventilation balancing measurements for room diffusers and return ducts
Pressure gaging in adjacent rooms for secondary airflow rates through wall openings for conveyor and the door contour
NUMERICAL METHODOLOGY
RANS ndash k-ω SST All y+ Wall Treatment Polyhedral cells
Cell count ~18M Coupled flow model 2nd order discretization
SOME RESULTS
Pressure gradient in RABS Undesirable longitudinal
velocity Remove partition Restore pressure in
capping section
Global pressure distribution
SOME RESULTS Before
After
Added panels in capping section
Transverse flow Plenum air flow
Non-sterile capping arm
RABS window with opening to cleanroom below
SOME RESULTS
Transverse flow Plenum air flow
Non-sterile capping arm
RABS window with opening to cleanroom below
Deflectors shift the air draft towards the machine floor
SOME RESULTS
Added deflectors
Impinging flow ndash accumulation table ndash focused simulation
SOME RESULTS
A focused simulation was performed with actual vials modeled and mapped boundary conditions from global simulation
Impinging flow ndash accumulation table ndash focused simulation
SOME RESULTS
A critical thickness was determined and used as a source for streamlines (backward and forward)
Simulations showed that in steady state the flow in contact with the critical thickness would entirely be evacuated through the vials shoulders
CONCLUSION
CONCLUSION
Advantages of StarCCM+ for the cleanroom analysis
1 Wrapping 2 Fast quality mesh 3 Nice visualisations for design
strategy explanations to client and regulatory agencies
Traditional smoke tests are still the
reference for accreditation even if 1 The smoke machine disturbs
the flow 2 It does not provide precise
velocities 3 The studied area is quite
small
CFD compensates those drawbacks and represents a valuable additional tool for cleanroom design
QUESTIONS
PHILIPPE B VINCENT CFD Engineer Creaform Engineering Services 5825 St-Georges Leacutevis Queacutebec G6V 4L2 Canada Phone (418) 833-4446 E-MAIL philippevincentametekcom WEB wwwcreaform3dcom
CONTACT
- Star Global 2015
- Agenda
- Our organization
- Our organization
- More than 2000 customers
- Numerical simulation Department
- Our project
- About our project
- About our project
- About our project
- Simulations
- Computational geometry
- Computational geometry
- Computational geometry
- Boundary conditions
- Numerical methodology
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Conclusion
- Conclusion
- Questions
-
Fit in a small suitcase Up and running in less than 5 minutes
No rigid set-up No particular experience from the user
Real time visualization Direct mesh output in StarCCM+ compatible STL format
COMPUTATIONAL GEOMETRY A word on portable scannershellip
Scanning demo details on the process and real-life examples of CFD analysis performed thanks to prior 3D scanning will be discussed in our 225 PM session in Pacific Room The Value of 3D Scanning Technologies as a Complementary Tool to STAR-CCM+reg for Various CFD Applications
BOUNDARY CONDITIONS
Each diffuser measured with Velocity Grid (Multiple pitot tubes)
Ventilation balancing measurements for room diffusers and return ducts
Pressure gaging in adjacent rooms for secondary airflow rates through wall openings for conveyor and the door contour
NUMERICAL METHODOLOGY
RANS ndash k-ω SST All y+ Wall Treatment Polyhedral cells
Cell count ~18M Coupled flow model 2nd order discretization
SOME RESULTS
Pressure gradient in RABS Undesirable longitudinal
velocity Remove partition Restore pressure in
capping section
Global pressure distribution
SOME RESULTS Before
After
Added panels in capping section
Transverse flow Plenum air flow
Non-sterile capping arm
RABS window with opening to cleanroom below
SOME RESULTS
Transverse flow Plenum air flow
Non-sterile capping arm
RABS window with opening to cleanroom below
Deflectors shift the air draft towards the machine floor
SOME RESULTS
Added deflectors
Impinging flow ndash accumulation table ndash focused simulation
SOME RESULTS
A focused simulation was performed with actual vials modeled and mapped boundary conditions from global simulation
Impinging flow ndash accumulation table ndash focused simulation
SOME RESULTS
A critical thickness was determined and used as a source for streamlines (backward and forward)
Simulations showed that in steady state the flow in contact with the critical thickness would entirely be evacuated through the vials shoulders
CONCLUSION
CONCLUSION
Advantages of StarCCM+ for the cleanroom analysis
1 Wrapping 2 Fast quality mesh 3 Nice visualisations for design
strategy explanations to client and regulatory agencies
Traditional smoke tests are still the
reference for accreditation even if 1 The smoke machine disturbs
the flow 2 It does not provide precise
velocities 3 The studied area is quite
small
CFD compensates those drawbacks and represents a valuable additional tool for cleanroom design
QUESTIONS
PHILIPPE B VINCENT CFD Engineer Creaform Engineering Services 5825 St-Georges Leacutevis Queacutebec G6V 4L2 Canada Phone (418) 833-4446 E-MAIL philippevincentametekcom WEB wwwcreaform3dcom
CONTACT
- Star Global 2015
- Agenda
- Our organization
- Our organization
- More than 2000 customers
- Numerical simulation Department
- Our project
- About our project
- About our project
- About our project
- Simulations
- Computational geometry
- Computational geometry
- Computational geometry
- Boundary conditions
- Numerical methodology
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Conclusion
- Conclusion
- Questions
-
BOUNDARY CONDITIONS
Each diffuser measured with Velocity Grid (Multiple pitot tubes)
Ventilation balancing measurements for room diffusers and return ducts
Pressure gaging in adjacent rooms for secondary airflow rates through wall openings for conveyor and the door contour
NUMERICAL METHODOLOGY
RANS ndash k-ω SST All y+ Wall Treatment Polyhedral cells
Cell count ~18M Coupled flow model 2nd order discretization
SOME RESULTS
Pressure gradient in RABS Undesirable longitudinal
velocity Remove partition Restore pressure in
capping section
Global pressure distribution
SOME RESULTS Before
After
Added panels in capping section
Transverse flow Plenum air flow
Non-sterile capping arm
RABS window with opening to cleanroom below
SOME RESULTS
Transverse flow Plenum air flow
Non-sterile capping arm
RABS window with opening to cleanroom below
Deflectors shift the air draft towards the machine floor
SOME RESULTS
Added deflectors
Impinging flow ndash accumulation table ndash focused simulation
SOME RESULTS
A focused simulation was performed with actual vials modeled and mapped boundary conditions from global simulation
Impinging flow ndash accumulation table ndash focused simulation
SOME RESULTS
A critical thickness was determined and used as a source for streamlines (backward and forward)
Simulations showed that in steady state the flow in contact with the critical thickness would entirely be evacuated through the vials shoulders
CONCLUSION
CONCLUSION
Advantages of StarCCM+ for the cleanroom analysis
1 Wrapping 2 Fast quality mesh 3 Nice visualisations for design
strategy explanations to client and regulatory agencies
Traditional smoke tests are still the
reference for accreditation even if 1 The smoke machine disturbs
the flow 2 It does not provide precise
velocities 3 The studied area is quite
small
CFD compensates those drawbacks and represents a valuable additional tool for cleanroom design
QUESTIONS
PHILIPPE B VINCENT CFD Engineer Creaform Engineering Services 5825 St-Georges Leacutevis Queacutebec G6V 4L2 Canada Phone (418) 833-4446 E-MAIL philippevincentametekcom WEB wwwcreaform3dcom
CONTACT
- Star Global 2015
- Agenda
- Our organization
- Our organization
- More than 2000 customers
- Numerical simulation Department
- Our project
- About our project
- About our project
- About our project
- Simulations
- Computational geometry
- Computational geometry
- Computational geometry
- Boundary conditions
- Numerical methodology
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Conclusion
- Conclusion
- Questions
-
NUMERICAL METHODOLOGY
RANS ndash k-ω SST All y+ Wall Treatment Polyhedral cells
Cell count ~18M Coupled flow model 2nd order discretization
SOME RESULTS
Pressure gradient in RABS Undesirable longitudinal
velocity Remove partition Restore pressure in
capping section
Global pressure distribution
SOME RESULTS Before
After
Added panels in capping section
Transverse flow Plenum air flow
Non-sterile capping arm
RABS window with opening to cleanroom below
SOME RESULTS
Transverse flow Plenum air flow
Non-sterile capping arm
RABS window with opening to cleanroom below
Deflectors shift the air draft towards the machine floor
SOME RESULTS
Added deflectors
Impinging flow ndash accumulation table ndash focused simulation
SOME RESULTS
A focused simulation was performed with actual vials modeled and mapped boundary conditions from global simulation
Impinging flow ndash accumulation table ndash focused simulation
SOME RESULTS
A critical thickness was determined and used as a source for streamlines (backward and forward)
Simulations showed that in steady state the flow in contact with the critical thickness would entirely be evacuated through the vials shoulders
CONCLUSION
CONCLUSION
Advantages of StarCCM+ for the cleanroom analysis
1 Wrapping 2 Fast quality mesh 3 Nice visualisations for design
strategy explanations to client and regulatory agencies
Traditional smoke tests are still the
reference for accreditation even if 1 The smoke machine disturbs
the flow 2 It does not provide precise
velocities 3 The studied area is quite
small
CFD compensates those drawbacks and represents a valuable additional tool for cleanroom design
QUESTIONS
PHILIPPE B VINCENT CFD Engineer Creaform Engineering Services 5825 St-Georges Leacutevis Queacutebec G6V 4L2 Canada Phone (418) 833-4446 E-MAIL philippevincentametekcom WEB wwwcreaform3dcom
CONTACT
- Star Global 2015
- Agenda
- Our organization
- Our organization
- More than 2000 customers
- Numerical simulation Department
- Our project
- About our project
- About our project
- About our project
- Simulations
- Computational geometry
- Computational geometry
- Computational geometry
- Boundary conditions
- Numerical methodology
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Conclusion
- Conclusion
- Questions
-
SOME RESULTS
Pressure gradient in RABS Undesirable longitudinal
velocity Remove partition Restore pressure in
capping section
Global pressure distribution
SOME RESULTS Before
After
Added panels in capping section
Transverse flow Plenum air flow
Non-sterile capping arm
RABS window with opening to cleanroom below
SOME RESULTS
Transverse flow Plenum air flow
Non-sterile capping arm
RABS window with opening to cleanroom below
Deflectors shift the air draft towards the machine floor
SOME RESULTS
Added deflectors
Impinging flow ndash accumulation table ndash focused simulation
SOME RESULTS
A focused simulation was performed with actual vials modeled and mapped boundary conditions from global simulation
Impinging flow ndash accumulation table ndash focused simulation
SOME RESULTS
A critical thickness was determined and used as a source for streamlines (backward and forward)
Simulations showed that in steady state the flow in contact with the critical thickness would entirely be evacuated through the vials shoulders
CONCLUSION
CONCLUSION
Advantages of StarCCM+ for the cleanroom analysis
1 Wrapping 2 Fast quality mesh 3 Nice visualisations for design
strategy explanations to client and regulatory agencies
Traditional smoke tests are still the
reference for accreditation even if 1 The smoke machine disturbs
the flow 2 It does not provide precise
velocities 3 The studied area is quite
small
CFD compensates those drawbacks and represents a valuable additional tool for cleanroom design
QUESTIONS
PHILIPPE B VINCENT CFD Engineer Creaform Engineering Services 5825 St-Georges Leacutevis Queacutebec G6V 4L2 Canada Phone (418) 833-4446 E-MAIL philippevincentametekcom WEB wwwcreaform3dcom
CONTACT
- Star Global 2015
- Agenda
- Our organization
- Our organization
- More than 2000 customers
- Numerical simulation Department
- Our project
- About our project
- About our project
- About our project
- Simulations
- Computational geometry
- Computational geometry
- Computational geometry
- Boundary conditions
- Numerical methodology
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Conclusion
- Conclusion
- Questions
-
Pressure gradient in RABS Undesirable longitudinal
velocity Remove partition Restore pressure in
capping section
Global pressure distribution
SOME RESULTS Before
After
Added panels in capping section
Transverse flow Plenum air flow
Non-sterile capping arm
RABS window with opening to cleanroom below
SOME RESULTS
Transverse flow Plenum air flow
Non-sterile capping arm
RABS window with opening to cleanroom below
Deflectors shift the air draft towards the machine floor
SOME RESULTS
Added deflectors
Impinging flow ndash accumulation table ndash focused simulation
SOME RESULTS
A focused simulation was performed with actual vials modeled and mapped boundary conditions from global simulation
Impinging flow ndash accumulation table ndash focused simulation
SOME RESULTS
A critical thickness was determined and used as a source for streamlines (backward and forward)
Simulations showed that in steady state the flow in contact with the critical thickness would entirely be evacuated through the vials shoulders
CONCLUSION
CONCLUSION
Advantages of StarCCM+ for the cleanroom analysis
1 Wrapping 2 Fast quality mesh 3 Nice visualisations for design
strategy explanations to client and regulatory agencies
Traditional smoke tests are still the
reference for accreditation even if 1 The smoke machine disturbs
the flow 2 It does not provide precise
velocities 3 The studied area is quite
small
CFD compensates those drawbacks and represents a valuable additional tool for cleanroom design
QUESTIONS
PHILIPPE B VINCENT CFD Engineer Creaform Engineering Services 5825 St-Georges Leacutevis Queacutebec G6V 4L2 Canada Phone (418) 833-4446 E-MAIL philippevincentametekcom WEB wwwcreaform3dcom
CONTACT
- Star Global 2015
- Agenda
- Our organization
- Our organization
- More than 2000 customers
- Numerical simulation Department
- Our project
- About our project
- About our project
- About our project
- Simulations
- Computational geometry
- Computational geometry
- Computational geometry
- Boundary conditions
- Numerical methodology
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Conclusion
- Conclusion
- Questions
-
Transverse flow Plenum air flow
Non-sterile capping arm
RABS window with opening to cleanroom below
SOME RESULTS
Transverse flow Plenum air flow
Non-sterile capping arm
RABS window with opening to cleanroom below
Deflectors shift the air draft towards the machine floor
SOME RESULTS
Added deflectors
Impinging flow ndash accumulation table ndash focused simulation
SOME RESULTS
A focused simulation was performed with actual vials modeled and mapped boundary conditions from global simulation
Impinging flow ndash accumulation table ndash focused simulation
SOME RESULTS
A critical thickness was determined and used as a source for streamlines (backward and forward)
Simulations showed that in steady state the flow in contact with the critical thickness would entirely be evacuated through the vials shoulders
CONCLUSION
CONCLUSION
Advantages of StarCCM+ for the cleanroom analysis
1 Wrapping 2 Fast quality mesh 3 Nice visualisations for design
strategy explanations to client and regulatory agencies
Traditional smoke tests are still the
reference for accreditation even if 1 The smoke machine disturbs
the flow 2 It does not provide precise
velocities 3 The studied area is quite
small
CFD compensates those drawbacks and represents a valuable additional tool for cleanroom design
QUESTIONS
PHILIPPE B VINCENT CFD Engineer Creaform Engineering Services 5825 St-Georges Leacutevis Queacutebec G6V 4L2 Canada Phone (418) 833-4446 E-MAIL philippevincentametekcom WEB wwwcreaform3dcom
CONTACT
- Star Global 2015
- Agenda
- Our organization
- Our organization
- More than 2000 customers
- Numerical simulation Department
- Our project
- About our project
- About our project
- About our project
- Simulations
- Computational geometry
- Computational geometry
- Computational geometry
- Boundary conditions
- Numerical methodology
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Conclusion
- Conclusion
- Questions
-
Transverse flow Plenum air flow
Non-sterile capping arm
RABS window with opening to cleanroom below
Deflectors shift the air draft towards the machine floor
SOME RESULTS
Added deflectors
Impinging flow ndash accumulation table ndash focused simulation
SOME RESULTS
A focused simulation was performed with actual vials modeled and mapped boundary conditions from global simulation
Impinging flow ndash accumulation table ndash focused simulation
SOME RESULTS
A critical thickness was determined and used as a source for streamlines (backward and forward)
Simulations showed that in steady state the flow in contact with the critical thickness would entirely be evacuated through the vials shoulders
CONCLUSION
CONCLUSION
Advantages of StarCCM+ for the cleanroom analysis
1 Wrapping 2 Fast quality mesh 3 Nice visualisations for design
strategy explanations to client and regulatory agencies
Traditional smoke tests are still the
reference for accreditation even if 1 The smoke machine disturbs
the flow 2 It does not provide precise
velocities 3 The studied area is quite
small
CFD compensates those drawbacks and represents a valuable additional tool for cleanroom design
QUESTIONS
PHILIPPE B VINCENT CFD Engineer Creaform Engineering Services 5825 St-Georges Leacutevis Queacutebec G6V 4L2 Canada Phone (418) 833-4446 E-MAIL philippevincentametekcom WEB wwwcreaform3dcom
CONTACT
- Star Global 2015
- Agenda
- Our organization
- Our organization
- More than 2000 customers
- Numerical simulation Department
- Our project
- About our project
- About our project
- About our project
- Simulations
- Computational geometry
- Computational geometry
- Computational geometry
- Boundary conditions
- Numerical methodology
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Conclusion
- Conclusion
- Questions
-
Impinging flow ndash accumulation table ndash focused simulation
SOME RESULTS
A focused simulation was performed with actual vials modeled and mapped boundary conditions from global simulation
Impinging flow ndash accumulation table ndash focused simulation
SOME RESULTS
A critical thickness was determined and used as a source for streamlines (backward and forward)
Simulations showed that in steady state the flow in contact with the critical thickness would entirely be evacuated through the vials shoulders
CONCLUSION
CONCLUSION
Advantages of StarCCM+ for the cleanroom analysis
1 Wrapping 2 Fast quality mesh 3 Nice visualisations for design
strategy explanations to client and regulatory agencies
Traditional smoke tests are still the
reference for accreditation even if 1 The smoke machine disturbs
the flow 2 It does not provide precise
velocities 3 The studied area is quite
small
CFD compensates those drawbacks and represents a valuable additional tool for cleanroom design
QUESTIONS
PHILIPPE B VINCENT CFD Engineer Creaform Engineering Services 5825 St-Georges Leacutevis Queacutebec G6V 4L2 Canada Phone (418) 833-4446 E-MAIL philippevincentametekcom WEB wwwcreaform3dcom
CONTACT
- Star Global 2015
- Agenda
- Our organization
- Our organization
- More than 2000 customers
- Numerical simulation Department
- Our project
- About our project
- About our project
- About our project
- Simulations
- Computational geometry
- Computational geometry
- Computational geometry
- Boundary conditions
- Numerical methodology
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Conclusion
- Conclusion
- Questions
-
Impinging flow ndash accumulation table ndash focused simulation
SOME RESULTS
A critical thickness was determined and used as a source for streamlines (backward and forward)
Simulations showed that in steady state the flow in contact with the critical thickness would entirely be evacuated through the vials shoulders
CONCLUSION
CONCLUSION
Advantages of StarCCM+ for the cleanroom analysis
1 Wrapping 2 Fast quality mesh 3 Nice visualisations for design
strategy explanations to client and regulatory agencies
Traditional smoke tests are still the
reference for accreditation even if 1 The smoke machine disturbs
the flow 2 It does not provide precise
velocities 3 The studied area is quite
small
CFD compensates those drawbacks and represents a valuable additional tool for cleanroom design
QUESTIONS
PHILIPPE B VINCENT CFD Engineer Creaform Engineering Services 5825 St-Georges Leacutevis Queacutebec G6V 4L2 Canada Phone (418) 833-4446 E-MAIL philippevincentametekcom WEB wwwcreaform3dcom
CONTACT
- Star Global 2015
- Agenda
- Our organization
- Our organization
- More than 2000 customers
- Numerical simulation Department
- Our project
- About our project
- About our project
- About our project
- Simulations
- Computational geometry
- Computational geometry
- Computational geometry
- Boundary conditions
- Numerical methodology
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Conclusion
- Conclusion
- Questions
-
CONCLUSION
CONCLUSION
Advantages of StarCCM+ for the cleanroom analysis
1 Wrapping 2 Fast quality mesh 3 Nice visualisations for design
strategy explanations to client and regulatory agencies
Traditional smoke tests are still the
reference for accreditation even if 1 The smoke machine disturbs
the flow 2 It does not provide precise
velocities 3 The studied area is quite
small
CFD compensates those drawbacks and represents a valuable additional tool for cleanroom design
QUESTIONS
PHILIPPE B VINCENT CFD Engineer Creaform Engineering Services 5825 St-Georges Leacutevis Queacutebec G6V 4L2 Canada Phone (418) 833-4446 E-MAIL philippevincentametekcom WEB wwwcreaform3dcom
CONTACT
- Star Global 2015
- Agenda
- Our organization
- Our organization
- More than 2000 customers
- Numerical simulation Department
- Our project
- About our project
- About our project
- About our project
- Simulations
- Computational geometry
- Computational geometry
- Computational geometry
- Boundary conditions
- Numerical methodology
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Conclusion
- Conclusion
- Questions
-
CONCLUSION
Advantages of StarCCM+ for the cleanroom analysis
1 Wrapping 2 Fast quality mesh 3 Nice visualisations for design
strategy explanations to client and regulatory agencies
Traditional smoke tests are still the
reference for accreditation even if 1 The smoke machine disturbs
the flow 2 It does not provide precise
velocities 3 The studied area is quite
small
CFD compensates those drawbacks and represents a valuable additional tool for cleanroom design
QUESTIONS
PHILIPPE B VINCENT CFD Engineer Creaform Engineering Services 5825 St-Georges Leacutevis Queacutebec G6V 4L2 Canada Phone (418) 833-4446 E-MAIL philippevincentametekcom WEB wwwcreaform3dcom
CONTACT
- Star Global 2015
- Agenda
- Our organization
- Our organization
- More than 2000 customers
- Numerical simulation Department
- Our project
- About our project
- About our project
- About our project
- Simulations
- Computational geometry
- Computational geometry
- Computational geometry
- Boundary conditions
- Numerical methodology
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Conclusion
- Conclusion
- Questions
-
QUESTIONS
PHILIPPE B VINCENT CFD Engineer Creaform Engineering Services 5825 St-Georges Leacutevis Queacutebec G6V 4L2 Canada Phone (418) 833-4446 E-MAIL philippevincentametekcom WEB wwwcreaform3dcom
CONTACT
- Star Global 2015
- Agenda
- Our organization
- Our organization
- More than 2000 customers
- Numerical simulation Department
- Our project
- About our project
- About our project
- About our project
- Simulations
- Computational geometry
- Computational geometry
- Computational geometry
- Boundary conditions
- Numerical methodology
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Some Results
- Conclusion
- Conclusion
- Questions
-