MELISSA MACZIS

EDUCATIONVirginia Commonwealth University-MCV, Richmond, VA 08/2014-CURRENT School of Medicine, Doctor of Philosophy (PhD)SLIPPERY ROCK UNIVERSITY, Slippery Rock, PA 08/2010-05/2013 Bachelor of Science in Biochemistry GPA: 3.634/4.0Bachelor of Science in Forensic Chemistry

Minor-CriminologyCARROLL COMMUNITY COLLEGE, Westminster, MD 08/2009-05/2010Associates of Arts and Science GPA: 3.75/4.0JUNIATA COLLEGE, Huntingdon, PA 08/2008-05/2009 BiologyRELEVANT EXPERIENCE BIOCHEMISTRY AND MOLECULAR BIOLOGY, PHD STUDENT 08/2014-CURRENT VCU, Department of Biochemistry and Molecular Biology, Dr. Sarah Spiegel’s Lab

Mass Spectrometry Cell Culture ELISA Assay qPCR and RT-PCR Western Blot Flow Cytometry Confocal and Electron Microscopy Breeding/genotyping/labeling transgenic mice Maintaining and Monitoring research animals Mentor and train Undergraduate researcher

LAB TECHNICIAN AND RESEARCHER 08/2013-08/2014 VCU, Department of Biomedical Engineering, Drs. Boyan/Schwartz/Olivares-Navarrete Lab

Relevant techniques: Micro-CT (reconstruction and analysis) PCR Breeding/genotyping/labeling transgenic mice Maintaining and Monitoring research animals Assistant in research surgery Cell Isolation Cell Culture

UNDERGRADUATE RESEARCHER 08/2010-05/2013Slippery Rock University, Department of Chemistry Supervisor: Dr. Paul BirckbichlerEffects of sodium butyrate, Ca 2+, and sodium butyrate with Ca 2+ on apoptotic levels and the localization of tissue transglutaminase in virus-transformed (VA13a) and normal human lung fibroblast cells (WI-38)Research Thesis, 05/2013

Relevant techniques: HEMA III Morphology staining Cell Culture Nexin Apoptosis Assay Indirect Immunofluorescence NIS-Element Software Prism Software Guava Flow Cytometer Electrophloresis and Western Blot ELISA Assay

ABSTRACT & PAPER PUBLICATION

Newton J, Hait NC, Maceyka M, Calaco A, Maczis M, Wassif CA, Caugnoux A, Porter FD, Milstien S, Platt N, Platt FM, Spiegel S. (2017 Jan). FTY720/fingolimod increases NPC1 and NPC2 expression and reduces cholesterol and sphingolipid accumulation in Niemann-Pick type C mutant fibroblast. FASEB. DOI: 10.1096/fj.201601041R.

Maczis M, Milstien S, Spiegel S. (2015 October). Sphingosine-1-Phosphate and Estrogen Signaling in Breast Cancer. Advances in Biological Regulation. doi: 10.1016/j.jbior.2015.09.006.

Teves ME1, Sundaresan G2, Cohen DJ3, Hyzy SL 3, Kajan I3, Maczis M 3, Zhang Z4, Costanzo RM5, Zweit J2, Schwartz Z3, Boyan BD6, Strauss JF 3rd4. (2015 May). Spag17 deficiency results in skeletal malformation and bone abnormalities. Plos One. 10 (5), e0125936. PMID: 26017218.(2015 October).

Z.Lin, J.Zhao, A. Ramsey, N. Rodriguez, M. Maczis, S.L. Hyzy, B.D. Boyan, Z. Schwartz. “The MicroRNA Profile of Extracellular Matrix Vesicles.”IADR/AADR/CADR.

Melissa Ann Maczis and Paul J. Birckbichler. "Differential apoptotic response in normal and virus-transformed human cells." FASEB JOURNAL.Vol.26. 9650 ROCKVILLE PIKE, BETHESDA, MD 20814: FEDERATION AMER SOC EXP BIOL, 2012.

POSTERS & PRESENTATIONS51st Annual Southeastern Regional Lipid Conference 2016 Rapid Responses to Steroid Hormone, 2016 2016 Massey Cancer Research Retreat, VCU12th Annual Women’s Health Research Day, VCU, 2016Graduate Symposium, VCU, 201650th Annual Southeastern Regional Lipid Conference 2015 Gordon Research Conference for “Transglutaminase in Human Disease Processes”Experimental Biology 2011 ConferenceNational Biochemistry and Molecular Biology Conference 2012Duquesne University Conference, 2011 and 2012UMBC Research Symposium, 2011 and 2012PNEACJS ConferenceHONORS AND AWARDS Student Travel Award at 51st SERLC, 11/2016Oral Presentation at 51st SERLC, 11/20163rd Place Poster Award at 2016 Massey Cancer Research RetreatBasic Science Research Award at 12th Annual Women’s Health Research Day, 2016Magna Cum LaudeDean’s List, 2009-2013Honor Society, 2009-2013Outstanding Senior Chemistry Major Award, 2012-2013Carlton F. Dresden Scholarship, 2011-2012Duquesne University Top Presentation Award, 2012Gordon Research Conference chosen Oral Presenter Outstanding Sophomore Chemistry Major Award, 2010-2011UMBC Research Symposium-2nd place Award, 2011The Honor Society of Phi Theta Kappa, 2009-2010CAMPUS INVOLVEMENT Undergraduate research Mentor, 2017BSDP PhD Student Recruiter, 2017-Orientation Tour Leader, 2016Women in Science (WIS), 2014-CurrentJunior Academy Reviewer, 2015Chemistry, Biology, Statistic and Calculus I Tutor, 2010-2013Teaching Assistant for FYRST Seminar, 2012Teaching Assistant for Biochemistry I and II Labs, 2012-2013

Student Board-Chemistry Representative, 2012-2013Orientation Leader, 2011-2013Chemistry and Biology Seminar Participation, 2010-2013Chemistry Showcase Representative, 2011-2013Chemistry Club Secretary, 2011-2012Slippery Rock University Chemistry Club Participant, 2010-2012Rugby, 2010-2012Cross Country and Track & Field, 2008-2009SKILLS

Experienced with GC/MS, HPLC, MS, ICP, AA, FTIR, and IR Proficient in SPE, Solvent extraction, and PCR Proficient in Microsoft Excel, Word, PowerPoint, and Professional Fluent in English (oral and written) Outstanding communication skills (oral and written) Excellent organizational skills and detail oriented