micro- and nanotechnologies for biology and healthcare
TRANSCRIPT
LETI-HEALTH
Adrienne Pervès
Deputy Director LETI Technologies for Biology and healthcare Department
Micro- NanoTechnologies for Healthcare and Biology
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Multidisciplinary teams - One stop shop for completely integrated systems
• Focused on applications in biology, healthcare, environment and security
• With a wide spectrum of competencies from component development to
system integration
MISSION AND EXPERTISE
Optic
Photonic
Packaging
Detection Electronic
Biology
Micro technology
Instru- mentation
Electro- chemistry
Micro fluidic
Modelling
Chemistry
Information processing
Micro- NanoTechnologies for Healthcare and Biology
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LETI HEALTH ONE STOP SHOP OFFER ON MEDICAL DEVICES
CHARACTERIZATION & VALIDATION CONCEPTION & MANUFACTURING
Converting concepts into manufacturable prototypes up to clinical tests
with high compliance to safety and security rules: our MedTech platform
Micro- NanoTechnologies for Healthcare and Biology
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COLLABORATION WITH MEDICAL TEAMS
More than 80 medical doctors in the world in more than 40 different domains Legend:
past
current
in discussion
Micro- NanoTechnologies for Healthcare and Biology
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KEY PARTNERS
Micro- NanoTechnologies for Healthcare and Biology
IMI-ECSEL Workshop
SENSORS AND DIAGNOSTIC – INPUTS FROM MICROFLUDICS
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THE 3 FUNCTIONAL PILLARS OF SENSING AND DIAGNOSTICS
Physical
elements
• Heartbeat
• Blood pressure
• Skin conductivity /
bioimpedence
• Activity / movement
• Brain activity (EEG-
ECoG)
• Muscle activity
• Eye activity (electrical,
movement)
Biochemical
elements in gaz (breath)
or in fluids
(sweat, urine,
blood, saliva,
swabs, etc.)
• Genomics (DNA,
RNA, SiRNA)
• Proteomics
(proteins)
• Metabolomics
(biomarkers,
glucose,
cholesterol,
hormones,
enzymes, ions, etc.)
Metabolic
pathologies (Diabetes,
obesity,
cholesterol,
cardiac diseases,
sleep disorders,
etc. )
Sampling
and sample
preparation
Analysis
Data
processing,
algorythms
Point of
Care
devices
In
vitro
Integration
Miniaturization
Multi-modal
systems
Multi-parameter
analysis
On
vivo
In vivo
Point of Care
devices
In vitro
On vivo
In vivo
Poin
t of C
are
devic
es
In v
itro
On v
ivo
In v
ivo
Po
int
of
Car
e
de
vice
s
In v
itro
On
viv
o
In v
ivo
Po
int o
f Care
devices
In vitro
On
vivo
In vivo
Data
processing
on large
patient
populations
Comprehensive picture of a single patient
condition Increased capacity to launch
large epidemiologic studies
Increased capacity for personalised medicine
Cancer
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The ambition of Makefluidics is to accelerate the maturation and take-off of the MF industry building on the work accomplished in MFManufacturing
Overall objective of MakeFluidics : From FCB to multi-module heterogeneous integration (Parallel with the evolution of the electronic industry)
PILOT LINES IN MICROFLUIDICS @ ECSEL
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Generic test bench FCB on which every FBB can be
connected
Fully assembled demonstrator
3D model of the characterization platform
(FLUIGENT).
Fully assembled demonstrator in MFM
Eveon Intuity® Mix
Demonstrators envisaged
In-vitro diagnostics for health
Particle metrology
Organ on chip
On-site drug preparation platform - EVEON
MicroFactory for radiotracer synthesis – Alcen PMB
Successful demonstrators in MFManufacturing
PILOT LINES IN MICROFLUIDICS @ ECSEL