micro biology & bio- technology

7/27/2019 Micro Biology & Bio- Technology

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MICRO BIOLOGY & BIO TECHNOLOGY

1. Gram ve bacteria containP) Teicoic acid Q) Lipid A R) Mycolic acid S) D-Polysaccharides

A. P, Q B. R,S C. P, R D. Q, S

2. The facultative anaerobic bacteria survive in presence of O2 is due toP) Lipase Q) Oxidase R) Catalase S) Peroxidase


3. Obligatory intracellular parasite isP) Bacteria Q) Fungi R) Virus S) Bacteriophase


4. The bacillus subtilis indicator is used for this type of sterilization

P) Hot air sterilization Q) Ethylene oxide sterilizationR) Moist heat sterilization S) Radiation sterilization


5. Endoflagella is present in

P) Mycobacteria Q) Spirochetes R) Bacillus sp. S) Treponium pollidumA. P, Q B. R,S C. P, R D. Q, S

6. The causative organism for tuberculosis isP) Mycobacterium tuberculosis Q) Mycobacterium meningitis

R) Mycobacterium bovis S) All the above

A. P, Q B. R,S C. P, R D. Q, S7. The antibody Ig has following property

P) It is first antibody synthesised in body

Q) It is first most antibody passively transferred from mother to baby

R) It is used to diagnose congental infectionS) It is used in iso immunization process

A. P, Q B. R,S C. P, R D. Q, S8. The antibody IgM has following propertyp) It is first antibody synthesised in body

Q) It is first most antibody passively transferred from mother to baby

R) It is used to diagnose congental infectionS) It is used in iso immunization process


9. Antibody activity is associated with

P) - globulin Q) - globulin R) pseudoglobulin S) - globulin


10. The example for poly valent vaccine

P) Polio vaccine Q) Yellow fever vaccine R) Influenja vaccine S) Deptheria toxoidA. P, Q B. R,S C. P, R D. Q, S

11. The example of live attenuated vaccine

P) BCG Q) Polio R) Cholera S) Rickettsial


12. The advantage of Alum precipitated toxoid is

P) Slowly absorbed Q) Slowly excreted R) Fast absorption S) Fast excretion



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13. The example for polysaccharide containing vaccine

P) Influenza Q) Preumococcal R) Cholera S) Perturis

A. P, Q B. R,S C. P, R D. Q, S14. The test organism for microbiological assay of streptomycin B

P) Bacillus subtilis Q) Bacillus pumium

R) Klebsiella pneumonia S) Staphylococcus aureusA. P, Q B. R,S C. P, R D. Q, S

15. The Staphylococcus aureus can be used as test organism for microbial assay of

P)Blemoycin Q) Amphotericin B R) Doxy cycline S) AmikacinA. P, Q B. R,S C. P, R D. Q, S

16. Diagnosic preparations for tuberculosis and diphtheria contains

A) Killed bacteria B. Attenuated bacteria C. Anti-toxins D. Rickettsial

17. Sabine vaccine is an example ofA. Killed vaccine B. Live attenuated vaccine C. Oral Vaccine D. Both B&C

18. Extreme hardness of endospore is due to

A. Gamma-picoline B. Murein C. Dipicolinic acid D. Both A& C

19. Brownes tubes are most commonly used chemical indicators forA. Ethylene oxide B. Radiation C. Heat sterilization D. Filtration

20. Plasmid is aA. Macromolecule involved in protein synthesis

B. Circular piece of duplex DNA

C. Hybrid DNA fragments D. Endogenous substances21. In the official bioassay of ERYTHROMYCIN the strain used is

A. B.subtilis B. Micrococcus luteus C. S. typhi D. E. coli

22. Staphylococcus aureus is used in the IP assay of

A. Doxycycline B. Bleomycin C. Kanamycin D. Carbeicillin23. The mechanism involved in simple staining is

A. Ion exchange B. Displacement C. Substitution D. Addition

24. The principle stain used in Acid-fast staining isA. malachite green B. Methylene blue C. Carbol fuschin D. Saffarin

25. Exotoxins possess following characteristics except

A. Thermolabile B. Protein in nature C. Highly toxic

D. Produced by gram negative organisms

26. This of the following chemical agents is used to destroy the pathogenicity without

altering its antigenic properties in the preparation of vaccines

A. Ethanol B. Methanol C. Acetaldehyde D. Formaldehyde27. From the following vaccines, which one cannot be prepared from the chick embryo

A. Measles vaccine B. Mumps vaccine C. Rubella vaccine D. Yellow fever vaccine

28. Colostrum, the initial secretion from the mothers breast after a baby is born is rich in

A. IgA B. IgM C. IgG D. Ig D

29. Alum is used regularly as an adjuvant in human immunizations because when given

with itA. Enhances immune response to a given immunogen

B. Confers the depo effect due to its insolubility

C. Potentiates the effect of antigens D. All the above


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30. Diagnostic preparations are used to test the individuals for

A. Susceptibility or immunity to a particular infection

B. A useful degree of protection after immunizationC. The presence of a particular disease D. All

31. The positive test with the tuberculin purified protein derivative indicated the person is

A. Immune to TB B. Non-immune to TB C. Both D. None32. Epidemic typhus is due to

A. Rickettsia felis B. Rickettsia prowazeki C. Rickettsia typhi D. All the above33. Which of the following antibody is implicated in erythroblastosis fetalis

A. IgA B. Ig M C. Ig G D. Ig D

34. Small pox vaccine mainly contains

A. Living virus vaccinia B. Living culture of M. tuberculae

C. Attenuated S. aureus D. Living virus of hepatitis35. The dose of tuberculin in Montoux test is

A. 0.01 ml B. 1 ml C. 0.1 ml D. 0.001 ml

36. Quantitative method used for detecting microbial antigens in biological fluid is

A. Coombs test B. Radio immune electrophoresisC.Nitro blue tetrazolium dye D. Counter current immune electrophoresis37. From the following select bacteria that can be identified by capsule staining

A. Corynebacterium diphtheria B. Streptococcus pneumoniaC. Mycobacterium pneumonia D. Staphylococcus aureus

38. Cold sterilization refers to sterilization withA. UV rays B. Steam at atmospheric pressure C. X-rays D. Both a&c

39. The stain used in Rideal walker test is

A. Salmonella typhi B. E.coli C. Staphylococcus aureus D. All the above

40. The immunodiagnostic test for Anthrax disease isA. Montoux test B. Schick test C. Ascolis test D. Naglers test

41. The immunodiagnostic test for Rheumatoid arthritis is

A. Paul-bunnel test B. Rose water test C. Weil-felix test D. Mc-faden test42. The antigenic determinant regions are called as

A. Epitope B. Domains C. Paratope D. Both a & b

43. The antibiotic activity was associated withA. Alpha globulin B. Pseudo globulin C. Beta globulin D. Gamma globulin

44. The first most antibody synthesized in the body

A. Ig M B. IgA C. Ig E D. Ig D

45. The antigen required for producing the agglutination reaction isA. Soluble B. Particulate C. Composite D. None

46. The Coombs is used for the detection of

A. Rh incompatibility in serum B. Incomplete Anti-Rh antibodies in serumC. Complete Anti-Rh antibodies in serum D. All the above

47. Viral vaccines are stored at a temperature

A. Cold B. Cool C. Frozen D. Room temperature48. Old tuberculin test is done to diagnose

A. Tuberculosis B. Diphtheria C. Typhoid D. Leprosy

49. Shicks test toxin is used to diagnose

A. Tuberculosis B. Diphtheria C. Typhoid D. Leprosy


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50. Influenza vaccine is grown on which part of egg

A. Allantonic fluid B. Chorioallontonic fluid C. Yolk sac D. Embryo

51. BCG vaccine is used to treatA. Cholera B. Tuberculosis C. BCG D. Pertussis

52. Which type of immunity develops slowly but lasts for long time

A. Active B. Passive C. Acquired D. All53. Antiserum contains

A. Antigens B. Antibodies C. Toxins D. Toxoid

54. The immunological products which produce active immunizationA. Bacterial vaccine B. Viral vaccine C. Toxoid D. All

55. An example for viral vaccine is

A. Small pox B. Polio mellitus C. Rabies D. All

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micro biology & bio- technology

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