Microbiology 1 (MICR V01)Summer 2010

Sec. 50284

Lecture: Dr. Marta D. de Jesus (Ph.D.)

TuWTh 3:00 - 5:50 PM (SCI-313)

Lab: Prof. Eden Bellenson

TuWTh 12:00 - 2:50 PM (SCI-311)

Please pick up all handouts.

IntroductionWhat is MICR V01? Nuts & bolts

RollSyllabusComments

Helps & Hints

College Website

http://www.venturacollege.edu

Your District Website:

http://my.vcccd.edu

Course Syllabus

A. COURSE DESCRIPTION

B. METHOD OF INSTRUCTION

C. STUDENT LEARNING OBJECTIVES

D. COURSE OBJECTIVES

E. COURSE TOPICS/UNITS

F. CORE COMPETENCIES

G. TEXTBOOK(S) AND REQUIRED SUPPLIES

Who is this class for?

Nursing: RN and beyond (BSN, MSN, PhD)

other pre-health: PharmD, OD, PA, etc. (possibly DVM)

other interests (bioengineering, chemical engineering, biotechnology, etc.)

Note: not usually recommended for MD or DO (not accepted as units by medical schools in general) or Microbiology majors.

Pre-requisites for Microbiology

CHEM V20 & V20L/V30 or V30 L/V 01 & V01L (requires beg. algebra) AND

PHSO V01 (requires ANAT V01 which requires BIOLV 01 & V01L) or BIOL V04

What topics did you get from those courses that you will use here?

Scientific method Metric system & conversions Subatomic particles, periodic table, element descriptions , chemical symbols & formulas Acids, bases/alkalis & buffers

Basic microscopy Prokaryotic & eukaryotic cells (plant & animal) Cell division Biological molecules (carbohydrates, lipids, proteins, nucleic acids)

Basic enzyme function DNA replication, RNA transcription & protein synthesis

Glycolysis, aerobic respiration, photosynthesis Basic taxonomy

Human anatomy & physiology (including an intro to the immune system)

If you don’t remember or are shaky on a number of these, this class will be very difficult.

Textbook

Also available:

1) CD-ROM & access to microbiologyplace website (comes with new texts or go to publisher website to purchase)

2) Study Guide (optional)

Course Syllabus

H. GRADING PLAN (p3)

(lecture %).75 + (lab %).25 = final %

Guaranteed grades

90-100% -> A

80-89% -> B

70-79% -> C

60-69% -> D

Below -> F

Course Syllabus

I. COURSE COMPONENT SPECIFICS

Quizzes: 10% (daily)

Lecture Tests: 40% (weekly)

Lecture Final: 25%

Please sit in the front half of the classroom for these

Lab: 25%

For Tests: 883

For Quizzes: 815

For Final Exam: 886

Course Syllabus

J. CLASSROOM RULES OF CONDUCT

http://www.venturacollege.edu/honesty/

1) Academic Dishonesty

2) Disruption/Obstruction of class

K. Some of the On-Campus Student Help

pg 29 & 49 Sched. Of Classes

http://www.assist.org

L. EMERGENCY PROCEDURES

Course Syllabus

M. Other miscellaneous helps

DISCLAIMER

Bloom’s Taxonomy (types of questions on college exams) p7

N. PLANNED SCHEDULE

AFFIDAVIT & Student Information Sheet - due tomorrow

IntroductionWhat is MICR V01? Nuts & bolts

RollSyllabusComments

Helps & Hints

Learning preferences/styles - 4 popular models

So what works? Everyone can/does use these different modes

VA(R)K (sensory)

Kolb

Sternberg

Dale’s Cone of Experience-

the more you’re involved, the more you get

Guaranteed: S+Q+3R+P Method of Studying

Survey

Question

Read

Recite

Review

PracticeHitch?

IntroductionWhat is Microbiology?

Microbes are:

1. small

Microbes are:

1. small

Microbes are:

1. small

16,600x

(when image is 2 in x 2 in)

Microbes are:

1. small

2. ubiquitous

Microbes are:

1. small

2. ubiquitous

3. ecologically important

Microbes are:

1. small

2. ubiquitous

3. ecologically important

4. medically important

trypanosomes

antibiotics

Microbes are:

1. small

2. ubiquitous

3. ecologically important

4. medically important

5. economically important

Microbes are:

1. small

2. ubiquitous

3. ecologically important

4. medically important

5. economically important

6. often beneficial

probiotics

bioremediation

& microbial ecology

(molecular biology)

(algology)

(More general: protistology)

(All kingdoms except plants)

What is Science?sciens (Latin)1. process/method

What is Science?sciens (Latin)1. process/method2. information

What is not Science? examplesArt LiteraturePhilosophyTheology/Religion

(and some subjects are in between…)

Scientific Method

In every experiment should have 2 groups:

experimental

control

In lab, sometimes have 2 kinds of controls:

positive

negative

Big Moments in the History of Microbiology

A. Diseases & microbes

1. ancient explanations, transmission

2. fermentation

3. spontaneous generation disproved (Aristotle, Redi, Needham, Spallanzani, Pasteur)

4. (in)famous diseases

a. Plague of Athens (430-25 B.C.E)

b. Black Plague (1348- outbreaks until 16th Cent. )

c. syphilis (~1500?)

d. Spanish Flu (1918)

e. HIV -> AIDS (late 20th Cent.-?)

People from text (before 1850)

Robert Hooke (1665)Antoni von Leeuwenhoek (1674)Francesco Redi (1668)Carolus Linnaeus (= Carl von Linne; 1735)John Needham (1745)Lazzaro Spallanzani (1765)Edward Jenner (1789)Theodor Schwann & Matthei Schleiden (1839)Ignaz Semmelweiss (1844)

After ~1855: Golden Age of Microbiology (some say 1857-1914)

Florence Nightingale (1854-6) Walter Reed (1900)John Snow (1854) Paul Ehrlich (1908)Rudolf Virchow (1858) Emil von Behring & Shibasaburo Kitasato

*Louis Pasteur (1857)* Albert Kluyver & C. B. van NielSergei Winogradsky (1885-8) Alexander Fleming (1928)Eduard Buchner (1897) Gerhard Domagk (1935)Joseph Lister (1865) Oswald Avery/Colin MacLeod/Maclyn McCarty (1944)

*Robert Koch (1876)* George Beadle & Edward Tatum (1958)Charles Laveran (1880) Linus Pauling (1965) Christian Gram (1884) Carl Woese (1977)Julius Richard Petri (1887)Dmitri Iwanoski (1892)Martinus Beijerink (1898)

http://www.microbeworld.org/index.php?option=com_content&view=category&layout=blog&id=64&Itemid=61

The 1950’s: electron microscopes

TEM

SEM

Emerging & re-emerging infectious diseases (EIDs)

http://www.niaid.nih.gov/topics/emerging/pages/list.aspx

Are we in the 2nd Golden Age of Microbiology?

Many say “yes”

- Most of modern biotechnology uses microbiology or techniques first developed with microbes.

- We know more about microbes now than ever before & the information is accelerating…

Example: We now know the entire DNA coding for more than many different bacterial species & more are being added all the time.

The first bacteria to be completely DNA sequenced was Haemophilus influenzae (1995, after many years of work). We now have labs that complete equivalent work in a few months (note: making a vaccine or drug takes far, far longer).