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Cognitive Health in the WorkplaceDr Jenny Barnett

Director, Healthcare Innovation

Mild Cognitive Impairment:

Uncovering the Impact on an Ageing Workforce

© CANTAB Corporate Health 2016. All rights reserved

CANTAB Corporate Health

Validated by 30 years of leading neuroscience research from Cambridge

Cognition, the leading global provider of cognitive assessment software in:

• Academic Research : 1,500+ published studies worldwide

• Clinical Drug Trials : 162 global trials

• Healthcare Provision: 25,000+ NHS assessments

Combining leading neuroscience and expertise in occupational health.

Helping employers and providers measure and manage cognitive health

using the latest digital tools.


What is cognition?

Memory & learning

Remember contacts, actions appointmentsLearn new names, procedures, systems

Attention

Ability to concentrateJuggle competing demands

Processing speed

Rapidly understanding information

Decision-making

Weigh up evidence Risk- and time- appropriate decisions


Everyd

ay m

em

ory p

ro

ble

m q

uesti

on

nair

e

CANTAB PAL total trials adjusted

120

100

80

60

40

20

0

120 10 20 30 40 50 60 70

• Stockbroker taking inappropriate financial risks

• Air traffic controller responding too slowly to an emerging risk

• Sales lead forgetting contacts or failing to follow up on agreed actions

• Programmer writing poor code

R=0.686; p<0.001

Real-world consequences of cognitive failures


Mild cognitive impairment (MCI)

• Impaired cognitive function in one or more domains• Milder than dementia, does not prevent independent functioning• A noticeable change from previous levels of functioning

MCI can be due to reversible causes such as

• Stress, anxiety or depression• Physical illness such as thyroid problems• Side-effects of medication

However, 70% eventually get diagnosed with a dementia.

Already, people aged 50+ represent 32% of working age population (ONS)

Much neurodegenerative disease takes hold in mid-life, many years before any obvious symptoms.


Cantab MobileMemory and mood assessment for ages 50+


400+GP Surgeries

Across 40Healthcare Authorities

25,000+cognitive assessments

Detecting dementia

earlier

Saving NHSTime & Cost

Memory impairment present in around

1 in 4 people

Early access to support

Most people reassured

avoiding referrals and costs

Usage in the NHS



3 out of 4 people would want to know if they were at risk of a neurological disorder

GE Healthcare: The Value of Knowing. Millward Brown, 2014

Benefits of early detection at work

Practical benefits

Reduces risk to the business and the individual

Enables proper and effective planning

Reduces uncertainty and distress

Lower diagnostic and treatment costs

Improved effectiveness of treatments

Timely advice and support


Paired Associates Learning (PAL)

Spatial Working Memory (SWM)

Matching to Sample (MTS)

Episodic Memory Working Memory Executive Function

Age, Education and Gender adjustment

Processing Speed Attention

Total errors Total Errors Strategy Score Proportional Slowing

% Correct% Correct

Mood

Score

Depression Scale

CANTAB Insight20-minute assessment for ages 18+


Reporting 5 cognitive functions across 6 levels of performance, adjusted for age, sex and education level


Common Causes of Cognitive Impairment

1. Royal College of Psychiatrists Position statement PS4/2010 2. NIMH, USA 3. McManus S, Meltzer H, Brugha T, et

al (2009) 4.HSE Work related Stress, Anxiety and Depression Statistics in Great Britain 2015 5.Mar et al (2015)

Spanish data

Recreational substance abuse

Depression, Anxiety,Stress

Early AD

24% have hazardous patterns of drinking6% alcohol dependence3% drug dependence1

Major depression: ~7% each year2

Common mental disorder: 18%3

43% of sick days due to stress4

½ of people over 60 are in early stages of AD but less than ½ will ever reach dementia5

Memory, New learning Executive function, attention, memory –some improvement with treatment

Learning and memory, impulse control and decision-making


Managing existing conditions aids cognition

Improvements after 6-months of antidepressant treatment

0

5

10

15

20

25

30

35

40

45

50

Duloxetine Escitalopram

Pre-treatment

Post-treatment

To

tal erro

rs (

SW

M)

Egerhazi et al., Neuropsych Hungar, 2013; see also Rock et al., Psych Med, 2013; Herrera-Guzman et al., Psych Res, 2010

Ryan et al (2006)

Improvements after 6-months of treatment for type 2 diabetes


Side effects of common drugs

Effects of single-doses of medication in healthy volunteers.


What Is Measured Can Be Managed

Physical & brain health are inextricably linked


Memory concerns are common –but technology allows easy, accurate measurement


Managing brain health better would have a huge impact on our workforce

A small shift in mean substantially decreases the number of people who are cognitively impaired and increases those functioning at peak performance.

Makes Sense.


www.cantabcorp.com

http://www.cantabcorp.com/

mild cognitive impairment - sterling eventssterlingevents.co.uk/files/haww/presentations/2016... ·...

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