ministry of health pediatric and adolescent hiv...
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Ministry of Health
NASCOP
PEDIATRIC AND ADOLESCENT HIV PROGRAM
Ministry of Health Kenya
Dr Laura OyiengoPediatric and Adolescent HIV Manager
Kenya Background
Total population ~ 42 million
HIV prevalence adults : 6.0%
~ 1.4 million estimated PLHIV
o 179,894 are children < 14 years
o 156,000 adolescent (10 – 19years)
o 1.2 million adults >15 years
Estimated 1.8 million pregnancies/yr
oHIV +ve pregnant women 74,764
oHIV Exposed Infants 74,764
Ministry of HealthNASCOP
PMTCT Program Progress, 2012-2015
61%
70%
66%
72%
36%
57%
63%
68%
0%
10%
20%
30%
40%
50%
60%
70%
80%
0
200000
400000
600000
800000
1000000
1200000
1400000
2012 2013 2014 Jan-June 2015
1st ANC Known Status HIV+ Pregnant women identified
% maternal prophylaxis coverage % infant prophylaxis coverage
July 2014: Start of B+
Ministry of HealthNASCOP
Use of Option B+ in PMTCT
37%
74%
98%
49%
21%
1%
0%
10%
20%
30%
40%
50%
60%
70%
80%
90%
100%
2013 2014 Jun, 2015
Interrupted ART
NVP only
(AZT + SdNVP)
ART
Trend of new child HIV infections due to Mother-Child transmission (6-weeks)
9.8
11.4
10.69.9
8.1 7.8
7
0
2
4
6
8
10
12
2008 2009 2010 2011 2012 2013 2014
EID
Po
sit
ivit
y R
ate
(%
)
Source – EID database
Ministry of HealthNASCOP
Results: 18-month Infant Outcomes
20159, 66%
500, 2%
1816, 6%
2914, 9%
4308, 14%
1015, 3% % Attending 18 month visit and ABnegative
% Attending 18 month visit and no ABtest done
% Identified as positive between 0 and18 months
% Transferred out between 0 and 18months
% Lost to Follow-Up between 0 and 18months
% Died between 0 and 18 months
July 2011 – Sept 2012 Cohort (n=30,712)
Linkage to care: 1580/1816 (87%)
7
Ministry of HealthNASCOP
PEDIATRIC TESTING UPTAKE – 2014 HIV TESTING SERVICES
RAPID RESULTS INITIATIVE
Ministry of HealthNASCOP
Justification for the HTS RRI
• Kenya AIDS Indicator Survey 2012 showed:• 53% of HIV infected persons were unaware of their HIV infection
• Amongst HIV infected women; only a third had taken their children for HIV testing
• More than half of all children aged 18 months to 14 years who had a parent infected with HIV had never been tested for HIV
Rapid Results Initiative (RRI) 2014@ CWC
Variable Number Positivity
1 Total Mothers tested in Post natal clinic
(CWC)
150,287
2 Total Mothers testing positive in PNC
(CWC)
9,532 6%
3 Total Infants 18 months and below tested
in CWC (specimen removed for PCR)
13,705
4 Total infants testing positive linking to
care
1,008 7.4%
Positivity Rate of Infants less than 18 months
County
Number of infants
<18 months tested
Number
positive % positivity
Uasin Gishu 19 12 63
Nyeri 146 44 30
Mombasa 242 68 28
Muranga 58 13 22
Machakos 87 15 17
Makueni 173 26 15
Siaya 747 105 14
Taita Taveta 112 15 13
Turkana 16 2 12
Bomet 154 16 10
Ministry of HealthNASCOP
Summary of the HTS RRI 2014
• Total 37,245 children of HIV positive mothers who had unknown HIV status• Migori – 6020 (16%)
• Homabay – 4139 (11%)
• Kirinyaga – 3572 (9.5%)
• Kitui- 2503 (6.7%)
• Nakuru – 2391(6.4%)
• Positivity rate of infants less than 18 months – 7.4%
• CONCLUSION:- SCALE UP PEDIATRIC HIV TESTING SERVICES IN HEALTH FACILITIES
Ministry of HealthNASCOP
ENROLLING CHILDREN INTO CARE
• Cohort Analysis Report – 2015
Strategic Information Unit - NASCOP
Ministry of HealthNASCOP
Method..
Data collection:
• 2,500 sites offering HIV care & treatment
• All sites using Electronic Medical Records were eligible
• Period under review: Jan 1, 2008 to Dec 31, 2014
• De identified patient records obtained
• CD4 % or count at enrollment for children <14years, was
reviewed.
Ministry of HealthNASCOP
CD4 at Enrollment
4%6%
13%
16%
16%
45%
Distribution CD4% at enrolment of pediatric 0-4yrs , N=5,211
0-4%
5-9%
10-14%
15-19%
20-24%
25%+
0%
10%
20%
30%
40%
50%
60%
70%
80%
90%
100%
5-9 yr 10-14 yr Total
Distribution of Paediatric CD4 count at enrolment by age
500+
350-499
250-349
0-249
Ministry of HealthNASCOP
Result 1 – CD4 at Enrollment
• While 45% of children aged 0-5 have a high CD4 at enrolment, reflecting the benefits of early identification and enrolment in care, over a quarter of children aged 5-14 are severely immuno-suppressed at enrolment, and the % suppressed increases with age.
• Testing at CWC (MNCH) will result in identification of “well” children
Ministry of HealthNASCOP
90-90-90 Cascade: ChildrenSeptember 2015
179894
83,500 75,393 71,654
78,40570,321 59,489
0
50000
100000
150000
200000
CLHIV Currently in Care Currently on ART Virally Suppressed
Achieved Gap
48%48%
52%52%
45%
55%
Ministry of HealthNASCOP
Viral suppression is consistently lower in children
96,585
71,654
0 20000 40000 60000 80000 100000 120000
Pediatric VL Tests
VLs Suppressed
Children Viral Load Testing and Suppression
Pediatric VL Tests VLs Suppressed
74%
Ministry of HealthNASCOP
Kenya AIDs Strategic Framework 2014/15-2018/19
22
A Kenya free of HIV new HIV infection, stigma and AIDS related deaths
Reduce new infections by
75%
Reduce AIDS related
mortality by 25%
Reduce HIV related stigma and
discrimination by 50%
Increase domestic
financing of the HIV
response to 50%
Contribute to achieving Vision 2030 through universal access to comprehensive HIV Prevention, Care and Treatment
Priority Interventions and Recommended Actions; SD 1 - 8 .
Ob
ject
ive
s
Ministry of HealthNASCOP
KASF Strategic DirectionsSTRATEGIC DIRECTIONS (SD)
SD 1:
Reducing new HIV infections
SD 2
Improving health outcomes and
wellness of all people living with HIV
SD 3
Using human rights approaches to
facilitate access to service for
PLHIV, key populations and other
priority groups in all sectors
SD 4
Strengthening integration of
health and community systems
SD 5
Strengthening research and innovation
to inform the KASF goals
SD 6
Promoting utilization of strategic
information, research and
monitoring and evaluation (M&E) to
enhance programming.
SD 7
Increasing domestic Financing
for sustainable HIV response
SD 8
Promoting accountable leadership for
delivery of the KASF results by all
sectors and actors
Ministry of HealthNASCOP
Linkages to care and
treatment
Access to ART
Retention , adherence
Treatment outcomes :
Viral suppression
Identification and diagnosis
24
KASF Targets SD 2 : 90-90-90 by 2019
90% of HIV infected persons are identified
90% on Antiretroviral therapy
90% of those on ART achieve viral suppression
2016/2017 2018/19
KA
SF G
oal
s
90% of PLHIV identified 90% of identified PLHIV on ART
Ch
ildre
n
Ad
ult
s
90% of PLHIV on ART virally suppressed
1,305,941
Road Map to 90-90-90: National Targets
Identify 80%
130,206 Treat 90 %
144,674
Identify 80%
Treat 90 %
Identify 90%
Treat 90 %
Identify 90%
Treat 90 %
161,905
145,714
1,175,347
1,169,576
1,052,619
Ministry of HealthNASCOP
WHAT DOES 90-90-90 MEAN FOR A CHILD
90% of all CLHIV are diagnosed
• HIV risk identified
• Taken for HIV test by caretaker
• Gets blood drawn
• Caretaker learns test results
90% of all diagnosed
CLHIV receive treatment
• Gets referred for care
• Is taken to clinic for care
• Caretaker learns how to manage HIV in child
• Child receives and starts ART
90% of all CLHIV on
treatment are virally
suppressed
• Is given ART as prescribed (lifelong)
• Is brought to clinic regularly for: - Adherence support, Clinic/lab evaluation, Medication refills & other health care services
• When appropriate, learns about HIV-positive status; begins managing own care
• Transitions to adolescent and later adult care
Ministry of HealthNASCOP
Accelerating Paediatric Treatment
• Lag in access to Paediatric ART
• Low identification
• Challenges in linkage
• Access to ART low
• Poor viral suppression
• High targets to meet!
Ministry of HealthNASCOP
IMPROVING PEDIATRIC ART IN KENYA
SUPPRESS
TREAT
TEST
COMMUNITY IndividualHouseholdSchool & institutions
FACILITY StaffService deliverySystems
COUNTY Leadership ManagementAccountability
NATIONAL Policy guidancePartnerships & NetworkingHealth financing
Ministry of HealthNASCOP
Populations are targeted!!
• All PLHIV
• Pregnant women
• Children
• Adolescents
• Adults
• KPs