mj pediatric products handbook

Pediatric Products Handbook

Leading the way in science-based

pediatric nutrition products, to help give

infants and children the best start in life.

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THE MISSION OF MEAD JOHNSONFor more than 100 years, Mead Johnson has been

providing science-based infant formulas and othernutritional products developed to help peoplelead healthier lives. Our company was founded byEdward Mead Johnson, whose son, Ted, sufferedfrom severe feeding difficulties and barelysurvived infancy. The experience helped inspireE. Mead to develop products that wouldprovide nutritional excellence to healthy infants as well as those with special dietaryrequirements. The same principles that guided

the company during its early days are still thebasis for its vision today:

Our Vision is to be the world’s leading provider ofscience-based pediatric nutrition products. We are

dedicated to helping provide infants and children withthe best start in life.

MJN Representative ______________________________________________________

Phone Number ___________________________________________________________

HEALTHCARE PROFESSIONAL CONTACT INFORMATION

1-800-457-3550Customer Service – To place an order.

1-812-429-6399 or [email protected] Service – Answers to product questions.

enfamilprofessional.comHealthcare Professionals – To get product information and more.

mjn.com/b2bordering Institutional Customer Order Center – For hospitals to order online and more.

CONSUMER CONTACT INFORMATION

1-800-BABY123 For parents.

enfamil.comA friendly source of information for moms.

The information in this handbook is provided as a service tohealthcare professionals. Every measure is taken to assure that thisis the most current and accurate information available. Because ourproducts are subject to revision, we ask that you please refer to theproduct label for the most accurate information.

IMPORTANT CONTACT INFORMATION

Pediatric Products Handbook

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Healthcare Professional and Consumer Resources

Home Delivery for Consumersenfamil.com/store

Consumers can order directly online for home delivery for their formula needs.

Healthcare Professional Resource Centerenfamilprofessional.com

Visit the Mead Johnson Nutrition HealthcareProfessional Resource Center for science-based pediatric nutrition products andclinical information. Pediatric and metabolicproduct information can be found online.

You’ll also have access to growth charts,formula preparation, storage and useinstructions, information booklets you candownload and print for your patients, andresources and links related to providerspecialties.

Product Findermjn.com/productfinder/productfinder.html

Consumers or healthcare professionals can searchby zip codes for stores that carry the Enfamil®

product of choice.

Institutional Customer Order Centermjn.com/b2bordering

Hospitals can go online to place new orders, create order templates, view our return policies,and access direct pricing lists 24/7.

Table of ContentsROUTINE FORMULAS

Enfamil® PREMIUM™ . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13Indication:Enfamil PREMIUM includes Natural Defense™ DualPrebiotics and is a milk-based, iron-fortified formulafor full-term infants.

Enfamil® RestFull™ . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19Indication:Enfamil RestFull is designed to gently thicken inbaby’s tummy and digest slowly for a natural way tohelp keep baby feeling satisfied.

SOLUTION AND MEDICAL NEEDS FORMULAS

Enfamil® Gentlease® . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24Indication:Enfamil Gentlease infant formula is clinically provento reduce fussiness or gas.**vs the same babies at the beginning of the study.

Enfamil A.R.® . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29Indication:Enfamil A.R. is clinically proven* to reduce frequent spit up.*Studied before the addition of DHA and ARA in infants whoregurgitate frequently (5 or more regurgitations a day).

Enfamil® ProSobee® . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35Indication:For babies with sensitive tummies, when a soyformula is preferred.

Nutramigen® with Enflora™ LGG®* . . . . . . . . . . . . 41*LGG is a registered trademark of Valio Ltd.

Indication:Nutramigen with Enflora LGG is an iron-fortified, lactose-free, galactose-free, sucrose-free, hypoallergenic

infant formula for term infants who are allergic to the intact proteins in cow’s milk and soy formulas, as well as other foods. Nutramigen with Enflora LGG contains extensively hydrolyzed protein to avoid an immune system response, and the probiotic LGG to support healthy and normal functioning of the GI tract.

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Nutramigen® (Liquids) . . . . . . . . . . . . . . . . . . . . . . . 47Indication:Nutramigen is an iron-fortified, lactose-free,hypoallergenic infant formula for term infants whoare allergic to the intact proteins in cow’s milk andsoy formulas, as well as other foods.

Nutramigen® AA™ . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 53Indication:Nutramigen AA is an iron-fortified, hypoallergenic,amino acid-based infant formula for the dietarymanagement of infants and toddlers with severe

cow’s milk protein allergy, not effectively managed by an extensivelyhydrolyzed formula. Nutramigen AA is also indicated for the dietarymanagement of infants and toddlers with multiple food proteinallergies.

Pregestimil® . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 58 Indication:Pregestimil is designed for infants who experience fat malabsorption and who may also be sensitive to intact proteins.

NICU PRODUCTS

Enfamil® Premature. . . . . . . . . . . . . . . . . . . . . . . . 65Indication:Enfamil Premature is specifically formulated tomeet the unique needs of rapidly growingpremature or low-birth-weight infants who donot receive human milk.

Enfamil® EnfaCare® . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 70Indication:Enfamil EnfaCare is designed with extra amounts ofimportant nutrients for the nutritional managementof infants who were born prematurely or with lowbirth weight.

Enfamil® Human Milk Fortifier . . . . . . . . . . . . . . . 76Indication:Enfamil Human Milk Fortifier is to be added toexpressed breast milk for feeding premature or low-birth-weight infants.

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HOSPITAL FEEDING SYSTEMS

Nursette® Bottles. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 82

Accessories . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 83

Hospital Gifts . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 86

ORAL ELECTROLYTE

Enfamil® Enfalyte®. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 88Indication:Enfamil Enfalyte is designed to be fed to infants andchildren for the maintenance of water and electrolytes thatmight otherwise be lost during vomiting and diarrhea.

TODDLER FORMULAS

Enfagrow™ PREMIUM™ NEXT STEP® . . . . . . . . . . . . . . . . . . . . . . . 92Indication:Enfagrow PREMIUM NEXT STEP is a milk-based formula for infantsor toddlers 10–36 months who are transitioning from infant formulaor breast milk.

Enfagrow™ Soy NEXT STEP®. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 97Indication:Enfagrow Soy NEXT STEP is a soy-based formula for infants ortoddlers 10–36 months who are transitioning from infant formula orbreast milk.

Enfagrow™ Gentlease® NEXT STEP® . . . . . . . . . . . . . . . . . . . . . . 102Indication:Enfagrow Gentlease NEXT STEP can be helpful in situations whereEnfamil Gentlease was used in infancy and sensitivity appears tocontinue into the toddler ages 10-36 months.

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Enfagrow™ PREMIUM™ Toddler Vanilla. . . . . . . . . . . . . . . . . . . 106Indication:Enfagrow PREMIUM Toddler Vanilla is a great-tasting, milk-basedformula for toddlers 12–36 months who are transitioning from infantformula or breast milk.

Enfagrow™ PREMIUM™ Toddler Chocolate . . . . . . . . . . . . . . 110Indication:Enfagrow PREMIUM Toddler Chocolate is a great-tasting, milk-basedformula for toddlers 12–36 months who are transitioning from infantformula or breast milk.

PRODUCTS FOR SPECIAL MEDICAL NEEDS

Portagen® . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 115Indication:Portagen is a nutritional powder for children and adultswith defects in the intraluminal hydrolysis of fat(decreased pancreatic lipase, decreased bile salts);

defective mucosal fat absorption (decreased mucosal permeability,decreased absorptive surface); and/or defective lymphatic transportof fat (ie, intestinal lymphatic obstruction). Portagen is notrecommended for use as an infant formula.

3232 A™ . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 119Indication:3232 A is a protein hydrolysate formula base that is tobe used with added carbohydrate. It contains tapiocastarch. It is for use in the dietary management of infants

and children with disaccharidase deficiencies or other disorders ofcarbohydrate metabolism under the direct and continuingsupervision of a doctor.

Enfaport® . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 124Indication:Enfaport is designed to meet the unique nutritionalneeds of infants with Chylothorax or LCHAD deficiency.

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METABOLIC FORMULAS

BCAD™ 1 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 129Indication:BCAD 1 is an isoleucine-, leucine-, and valine-free, iron-fortified dietary powder for the dietary management ofinfants and toddlers with maple syrup urine disease(MSUD).

BCAD™ 2 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 133Indication:BCAD 2 is a dietary powder that is free of the branchedchain amino acids, isoleucine, leucine, and valine, forchildren and adults with maple syrup urine disease(MSUD) or other inborn errors of branched chain aminoacid metabolism.

GA™ . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 137Indication:GA is a lysine- and tryptophan-free, iron-fortified dietarypowder for infants, children, and adults with glutaricacidemia type I.

HCY™ 1 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 141Indication:HCY 1 is a methionine-free, iron-fortified dietary powderfor infants and toddlers with homocystinuria.

HCY™ 2 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 145Indication:HCY 2 is a methionine-free dietary powder for childrenand adults with homocystinuria.

LMD™ . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 148Indication:LMD is a leucine-free, iron-fortified dietary powder forinfants, children, and adults with disorders of leucinemetabolism, including isovaleric acidemia.

OA™ 1 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 152Indication:OA 1 is an isoleucine-, methionine-, threonine-, andvaline-free, iron-fortified dietary powder for infants andtoddlers with propionic acidemia or methylmalonicacidemia.

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OA™ 2 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 156Indication:OA 2 is an isoleucine-, methionine-, threonine-, andvaline-free dietary powder for the dietary managementof children and adults with propionic acidemia ormethylmalonic acidemia.

PFD™ 1 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 160Indication:PFD 1 is a protein- and amino acid-free productdesigned with carbohydrates, vitamins, and minerals aswell as the essential fatty acids for infants and toddlerswith various amino acid metabolic disorders.

PFD™ 2 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 164Indication:PFD 2 is a protein- and amino acid-free productdesigned to help meet the calorie, vitamin, mineral, andessential fatty acid needs of children and adults withamino acid metabolic disorders.

Phenyl-Free® 1 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 167Indication:Phenyl-Free 1 is a phenylalanine-free, iron-fortifieddietary powder for infants and toddlers withphenylketonuria (PKU).

Phenyl-Free® 2 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 171Indication:Phenyl-Free 2 is a phenylalanine-free dietary powder forchildren and adults with phenylketonuria (PKU).

Phenyl-Free® 2 HP. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 175Indication:Phenyl-Free 2 HP is a high protein equivalent,phenylalanine-free dietary powder for children andadults with phenylketonuria (PKU).

TYROS™ 1 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 179Indication:TYROS 1 is a phenylalanine- and tyrosine-free, iron-fortified dietary powder for infants and toddlers withtyrosinemia.

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METABOLIC FORMULAS (CONT.)

TYROS™ 2 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 183Indication:TYROS 2 is a phenylalanine- and tyrosine-free dietarypowder for children and adults with inborn errors oftyrosine metabolism including tyrosinemia type II.

WND® 1 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 187Indication:WND 1 is a nonessential amino acid-free, iron-fortifieddietary powder for infants and toddlers with inbornerrors of the urea cycle.

WND® 2 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 191Indication:WND 2 is a dietary powder that is free of nonessentialamino acids for children and adults with inborn errors ofthe urea cycle.

DIETARY SUPPLEMENTS

Enfamil® D-Vi-Sol™ Drops . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 195Indication:Vitamin D supplement for infants and children.

Enfamil® Poly-Vi-Sol® Drops . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 197Indication:Multivitamin supplementation for infants and children.

Enfamil® Poly-Vi-Sol® with Iron Drops . . . . . . . . . . . . . . . . . . . . 199Indication:Multivitamin and iron supplementation for infants and children.

Enfamil® Tri-Vi-Sol® Drops . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 202Indication:Vitamins A, C, and D supplementation.

Enfamil® Tri-Vi-Sol® with Iron Drops . . . . . . . . . . . . . . . . . . . . . . 204Indication:Vitamins A, C, and D, and iron supplementation.

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Enfamil® Fer-ln-Sol® Drops. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 206Indication:Dosage forms are appropriate to provide supplementary iron needs for infants and children. Infants who may especially requiresupplemental iron include infants of anemic mothers, low-birth-weight infants, and infants of mothers with poorly controlleddiabetes.

Expecta® LIPIL® DHA Supplement . . . . . . . . . . . . 208Indication:Expecta LIPIL DHA Supplement is for pregnant andnursing women. It helps supply the DHA their diet maylack. For adults only. The patient should consult herdoctor before taking any supplement.

ADDITIONAL PRODUCT INFORMATION

Product Ordering Guide. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 212• Item Numbers• Product• Descriptions• Unit Size• Calories/Unit• Product Yield/Unit• Case Size• HCPCS Code• NDC Number

Formula Dilution Instructions. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 216

Approximate Conversion Tables . . . . . . . . . . . . . . . . . . . . . . . . . . 224

Caloric Distribution Table . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 225

Kosher Products . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 226

Osmolality/Osmolarity Table . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 227

Potential Renal Solute Load Tables. . . . . . . . . . . . . . . . . . . . . . . 228

Hospital or Institutional Storage Guidelines. . . . . . . . . . . . 229

Tube Feeding Hang Times . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 229

Infant Formula Amino Acid Compositions . . . . . . . . . . . . . . 230

Metabolic Formula Amino Acid Compositions . . . . . . . . . 234

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Enfamil® PREMIUM™

Natural Defense™

Dual PrebioticsMilk-based Infant Formula for the First 12 Months

INDICATIONEnfamil PREMIUM includes Natural Defense Dual Prebiotics and is a milk-based,iron-fortified formula for full-term infants.1,2 Enfamil PREMIUM offers proven*clinical outcomes in 3 key areas: growth, brain and eye, and immune systemdevelopment.

According to the AAP, iron-fortified infant formula should be used if breast-feeding is not chosen, is discontinued during the first year, or if a supplement to breast milk is desired.3 Cow’s milk is not recommended for infants before their first birthday.

PRODUCT FEATURES • Milk-based infant formula patterned after breast milk

• Infants fed this formulation may have softer stools, more like those of abreastfed infant, compared to infants fed formula without prebiotics

• Patented Natural Defense prebiotic blend of 2 prebiotic ingredients – GOS(galactooligosaccharides) and polydextrose – to support the growth of healthygut bacteria, which help support the immune function

• Clinically proven* growth similar to breastfed infants through 12 months, IQscores and vision similar to breastfed infants up to 4 years of age, and supportfor the immune system

• DHA levels similar to the worldwide breast milk averages4,†

• Easy-to-digest, intact milk protein (60:40 whey-to-casein ratio) patterned afterbreast milk5,‡

*Studied before the addition of prebiotics†Average level of DHA in worldwide breast milk is 0.32% ± 0.22% (mean ± standarddeviation of total fatty acids) based on an analysis of 65 studies of 2,474 women.

‡Comparison based on whey:casein ratio of typical mature breast milk (15 days to 6months after birth).

Refer to enfamilprofessional.com for formulation of Enfamil PREMIUM prior to April 1, 2010.

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NUTRIENTS§

(Normal Dilution) Per 100 Calories Per 100 grams(5 fl oz) Powder (500 Cal)

Protein, g 2.1 10.6Fat, g 5.3 27

Linoleic acid, mg 860 4300DHA, mg 17 86ARA, mg 34 172

Carbohydrate, g 11.2 57Water, g 133 2.4Vitamins/Other Nutrients

Vitamin A, IU 300 1510Vitamin D, IU 60 300Vitamin E, IU 2 10.1Vitamin K, mcg 9 45Thiamin (Vitamin B1), mcg 80 400Riboflavin (Vitamin B2), mcg 140 710Vitamin B6, mcg 60 300Vitamin B12, mcg 0.3 1.51Niacin, mcg 1000 5000Folic acid (Folacin), mcg 16 81Pantothenic acid, mcg 500 2500Biotin, mcg 3 15.1Vitamin C (Ascorbic acid), mg 12 61Choline, mg 24 121Inositol, mg 6 30Carnitine, mg 2 10.1Taurine, mg 6 30

MineralsCalcium, mg 78 390Phosphorus, mg 43 220Magnesium, mg 8 40Iron, mg 1.8 9.1Zinc, mg 1 5Manganese, mcg 15 76Copper, mcg 75 380Iodine, mcg 15 76Selenium, mcg 2.8 14.1Sodium, mg 27 136Potassium, mg 108 550Chloride, mg 63 320Molybdenum, mcg NA NAChromium, mcg NA NA

§Product nutrient values and ingredients are subject to change. Please see product labelfor current information.

NA=None Added

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NUTRIENT FACTSNutrient Density 20 Calories/fl ozProtein (% calories) 8.5Fat (% calories) 48Carbohydrate (% calories) 43.5Potential Renal Solute Load (mOsm/100 Calories)6 19.1Potential Renal Solute Load (mOsm/100 mL)6 12.9 (Pwd)

13 (Liq)Osmolality (mOsm/kg water) 300Osmolarity (mOsm/L) 270Gluten-Free YesLactose-Free NoGalactose-Free No

PRODUCT FORMSEnfamil® PREMIUM™ is available in powder, ready-to-use liquid, and concentrate.For ordering information, please refer to page 212.

COMPOSITIONIngredients: Powder: Nonfat milk, lactose, vegetable oil (palm olein, coconut,soy, and high oleic sunflower oils), whey protein concentrate, galactooligo-saccharides,|| polydextrose,|| and less than 1%: Mortierella alpina oil,¶

Crypthecodinium oil,# calcium carbonate, potassium citrate, ferrous sulfate,potassium chloride, magnesium oxide, sodium chloride, zinc sulfate, cupricsulfate, manganese sulfate, sodium selenite, soy lecithin, choline chloride,ascorbic acid, niacinamide, calcium pantothenate, vitamin A palmitate, vitaminB12, vitamin D3, riboflavin, thiamin hydrochloride, vitamin B6 hydrochloride, folic acid, vitamin K1, biotin, inositol, vitamin E acetate, nucleotides (cytidine5’-monophosphate, disodium uridine 5’-monophosphate, adenosine5’-monophosphate, disodium guanosine 5’-monophosphate), taurine,L-carnitine.

Ingredients: Ready To Use: Reduced minerals whey, nonfat milk, vegetable oil(palm olein, soy, coconut, and high oleic sunflower oils), and less than 2%:galactooligosaccharides,|| polydextrose,|| Mortierella alpina oil,¶ Crypthecodiniumoil,# lactose, potassium citrate, calcium carbonate, calcium chloride, sodiumchloride, calcium phosphate, ferrous sulfate, sodium citrate, zinc sulfate, cupricsulfate, manganese sulfate, sodium selenite, mono- and diglycerides, soylecithin, ascorbic acid, sodium ascorbate, vitamin B12, vitamin D3, vitamin Eacetate, niacinamide, calcium pantothenate, vitamin A palmitate, thiaminhydrochloride, vitamin B6 hydrochloride, folic acid, vitamin K1, biotin,carrageenan, choline chloride, inositol, nucleotides (cytidine 5’-monophosphate,adenosine 5’-monophosphate, disodium guanosine 5’-monophosphate,disodium uridine 5’-monophosphate), taurine.||A type of prebiotic.¶A source of arachidonic acid (ARA).#A source of docosahexaenoic acid (DHA).

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Ingredients: Concentrated Liquid: Reduced minerals whey, nonfat milk,vegetable oil (palm olein, soy, coconut, and high oleic sunflower oils), lactose,and less than 2%: galactooligosaccharides,|| polydextrose,|| Mortierella alpina oil,¶

Crypthecodinium oil,# potassium citrate, calcium carbonate, calcium chloride,sodium chloride, calcium phosphate, sodium citrate, ferrous sulfate, zinc sulfate,cupric sulfate, manganese sulfate, sodium selenite, soy lecithin, mono- anddiglycerides, ascorbic acid, sodium ascorbate, vitamin B12, vitamin D3, vitamin Eacetate, niacinamide, calcium pantothenate, vitamin A palmitate, thiaminhydrochloride, vitamin B6 hydrochloride, folic acid, vitamin K1, biotin,carrageenan, choline chloride, inositol, nucleotides (cytidine 5’-monophosphate,adenosine 5’-monophosphate, disodium guanosine 5’-monophosphate,disodium uridine 5’-monophosphate), taurine.||A type of prebiotic.¶A source of arachidonic acid (ARA).#A source of docosahexaenoic acid (DHA).

POTENTIAL ALLERGENSEnfamil® PREMIUM™ contains milk and soy.

PREPARATION OF FEEDINGSThe baby’s health depends on carefully following these instructions. Properhygiene, preparation, dilution, use, and storage are important whenpreparing infant formula. Powdered infant formulas are not sterile andshould not be fed to premature infants or infants who might have immuneproblems, unless directed and supervised by a doctor.

Discuss with parents whether they need to use cooled, boiled water for mixingand whether they need to boil clean utensils, bottles, and nipples in water beforeuse.

Powder

1. Wash hands thoroughly with soap and water before preparing formula.

2. Pour desired amount of water into bottle. Add powder.

3. Cap bottle and SHAKE WELL.

Use the following chart for correct amounts of water and powder. Use scoop incan to measure powder. Store DRY scoop in its original can.

To Make** Water Powder Weight2 fl oz 2 fl oz 1 unpacked level scoop 8.8 g4 fl oz 4 fl oz 2 unpacked level scoops 17.6 g6 fl oz 6 fl oz 3 unpacked level scoops 26.4 g8 fl oz 8 fl oz 4 unpacked level scoops 35.2 g1 quart 28.5 fl oz 1 unpacked level household 127 g

measuring cup + 2 unpacked Tbsps

**Each scoop adds about 0.2 fl oz to the amount of prepared formula.

Failure to follow these instructions could result in severe harm. Onceprepared, infant formula can spoil quickly. Either feed immediately or coverand store in the refrigerator at 35–40°F (2–4°C) for no longer than 24 hours. Donot use prepared formula if it is unrefrigerated for more than a total of 2 hours.Do not freeze prepared formula. After feeding begins, do not refrigerate feedingbottle; you must use within 1 hour or discard.

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Powder Storage

Store cans at room temperature. After opening can, keep tightly covered, storein dry area, and use contents within 1 month. Do not freeze powder and avoidexcessive heat. Use by date on bottom of can.

Ready To Use

1. Wash hands thoroughly with soap and water before preparing bottle forfeeding.

2. Clean can lid, SHAKE CAN WELL, and open.

3. Pour into bottle(s).

Failure to follow these instructions could result in severe harm. Opened cansand prepared bottles can spoil quickly. Either feed immediately or cover andstore in refrigerator at 35–40°F (2–4°C) for no longer than 48 hours. Do not useopened can and/or prepared bottle if they are unrefrigerated for more than atotal of 2 hours. Do not freeze prepared bottle. After feeding begins, do notrefrigerate feeding bottle. You must use within 1 hour or discard.

Ready To Use Storage

Store unopened cans at room temperature. Avoid excessive heat. Do not freeze.Use by date on top of can.

Nursette® Bottles

1. Inspect each bottle for signs of damage.


3. SHAKE BOTTLE WELL and remove cap.

4. Attach nipple unit (not included).

Failure to follow these instructions could result in severe harm. Openedbottles can spoil quickly. Either feed immediately or replace cap and store inrefrigerator at 35–40°F (2–4°C) for no longer than 48 hours. Do not use openedbottle if it is unrefrigerated for more than a total of 2 hours. Do not freeze. Afterfeeding begins, do not refrigerate feeding bottle. You must use within 1 hour ordiscard.

Nursette Bottle Storage

Store unopened bottles at room temperature. Avoid excessive heat andprolonged exposure to light. Do not freeze. Use by date on carton and bottlelabel.

Concentrate



3. Pour desired amount of water into the bottle. Add an equal amount ofconcentrated liquid. SHAKE OR STIR WELL.

Failure to follow these instructions could result in severe harm. Opened cansand prepared formula can spoil quickly. Either feed immediately or cover andstore in refrigerator at 35–40°F (2–4°C) for no longer than 48 hours. Do not useopened can and/or prepared formula if they are unrefrigerated for more than atotal of 2 hours. Do not freeze prepared formula. After feeding begins, do notrefrigerate feeding bottle. You must use within 1 hour or discard.

17

Enfam

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RE

MIU

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Concentrate Storage


CAUTION

Use product by date on container.

Nutritional powders are not sterile.

WARNING: Do not use a microwave oven to prepare or warm formula. Seriousburns may result.

REFERENCES1. Ziegler EE, Vanderhoof JA, Petschow BW, et al., Term infants fed formula

supplemented with selected blends of prebiotics grow normally and have soft stoolssimilar to those reported for breast-fed infants. J Pediatr Gastroenterol Nutr. 2007;44:359-364.

2. Nakamura N, Gaskins HR, Collier CT, et al., Molecular ecological analysis of fecalbacterial populations from term infants fed formula supplemented with selectedblends of prebiotics. Appl Environ Microbiol. 2009; 75:1121-1128.

3. American Academy of Pediatrics, Committee on Nutrition. Iron fortification of infantformulas. Pediatrics. 1999;104:119-123. Reaffirmed 11/02.

4. Brenna JA, Varamini B, Jensen RG, Diersen-Schade DA, Boettcher JA & Arterbum CM.Docosahexaenoic and arachidonic acid concentrations in human milk worldwide.Am J Clin Nutr; 85:1457-64.

5. Kunz C, Lönnerdal B. Re-evaluation of the whey protein/casein ratio of human milk.Acta Paediatr. 1992;81:107-112.

6. Fomon SJ, Ziegler EE. Renal solute load and potential renal solute load in infancy.J Pediatr. 1999;134:11-14.

For additional information, please visit enfamilprofessional.com

18

Enfamil® RestFull™For Bedtime Feeding

INDICATIONEnfamil RestFull is designed to gently thicken in baby’s tummy and digest slowlyfor a natural way to help keep baby feeling satisfied. When a baby’s final feedingbefore bedtime keeps him satisfied for longer, better sleep is a better possibility.Enfamil RestFull is the same formulation as Enfamil A.R.®

Long-Term Usage

While Enfamil RestFull is designed for bedtime feedings, it can provide a solesource of nutrition for infants up to age 6 months, and provide a major source ofnutrition until 12 months. Normally, in feeding infants, gradual introduction ofsolid foods after 4–6 months of age is an important developmental as well asnutritional step. (See Table of Contents for other types of products appropriatefor toddlers and children.)

PRODUCT FEATURES Enfamil RestFull contains a rice carbohydrate that is designed to gently thicken inbaby’s tummy.

19

Enfam

il ®R

estFull ™

NUTRIENTS*(Normal Dilution) Per 100 Calories Per 100 grams

(5 fl oz) Powder (500 Cal)Protein, g 2.5 12.4Fat, g 5.1 25

Linoleic acid, mg 860 4300Linolenic acid, mg 85 420DHA, mg 17 84ARA, mg 34 169

Carbohydrate, g 11 55Water, g 134 3Vitamins/Other Nutrients



*Product nutrient values and ingredients are subject to change. Please see product labelfor current information.

NA=None Added

20

NUTRIENT FACTSNutrient Density 20 Calories/fl ozProtein (% calories) 10Fat (% calories) 46Carbohydrate (% calories) 44Potential Renal Solute Load (mOsm/100 Calories)1 23Potential Renal Solute Load (mOsm/100 mL)1 15.3Osmolality (mOsm/kg water) 230Osmolarity (mOsm/L) 210Gluten-Free YesLactose-Free NoGalactose-Free No

PRODUCT FORMEnfamil® RestFull™ is available in powder. For ordering information, please referto page 212.

COMPOSITIONIngredients: Powder: Nonfat milk, vegetable oil (palm olein, soy, coconut, andhigh oleic sunflower oils), rice starch, lactose, maltodextrin, and less than 2%:Mortierella alpina oil,† Crypthecodinium cohnii oil,‡ vitamin A palmitate, vitaminD3, vitamin E acetate, vitamin K1, thiamin hydrochloride, riboflavin, vitamin B6

hydrochloride, vitamin B12, niacinamide, folic acid, calcium carbonate, calciumpantothenate, biotin, ascorbic acid, choline chloride, inositol, ferrous sulfate, zincsulfate, manganese sulfate, cupric sulfate, sodium selenite, sodium citrate,potassium hydroxide, taurine, L-carnitine.†A source of arachidonic acid (ARA).‡A source of docosahexaenoic acid (DHA).

POTENTIAL ALLERGENSEnfamil RestFull contains milk and soy.



Powder



3. Cap bottle and SHAKE WELL. Let bottle sit 5 minutes.


21

Enfam

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estFull ™

To Make§ Water Powder Weight2 fl oz 2 fl oz 1 unpacked level scoop 8.7 g4 fl oz 4 fl oz 2 unpacked level scoops 17.4 g6 fl oz 6 fl oz 3 unpacked level scoops 26.1 g8 fl oz 8 fl oz 4 unpacked level scoops 34.8 g1 quart 29 fl oz 11⁄3 unpacked level 129 g

household measuring cup

§Each scoop adds about 0.2 fl oz to the amount of prepared formula.

Failure to follow these instructions could result in severe harm. Onceprepared, infant formula can spoil quickly. Either feed immediately or coverand store in the refrigerator at 35–40°F (2–4°C) for no longer than 24 hours. Donot use prepared formula if it is unrefrigerated for more than a total of 2 hours. Do not freeze prepared formula. After feeding begins, do not refrigerate feedingbottle; you must use within 1 hour or discard.

Powder Storage

Store cans at room temperature. After opening can, keep tightly covered, storein dry area, and use contents within 1 month. Do not freeze powder. Avoidexcessive heat. Use by date on bottom of can.

CAUTION




REFERENCES1. Fomon SJ, Ziegler EE. Renal solute load and potential renal solute in infancy.

J Pediatr. 1999;134:11-14.


22

Solution andMedical NeedsFormulas

Enfamil® Gentlease®

For Fussiness and Gas

Milk-based infant formula with partially broken downproteins for the first 12 months

INDICATIONEnfamil Gentlease infant formula is clinically proven to reduce fussiness or gas.1,*It contains an easy-to-digest milk protein blend patterned after breast milk (wheyand casein in a 60:40 ratio)† that has been partially broken down. EnfamilGentlease also has reduced levels of lactose (about 1⁄5 the lactose of a fulllactose, routine, milk-based formula), for infants who may show transientintolerance to lactose. The formula is nutritionally balanced and includesdocosahexaenoic acid (DHA) and arachidonic acid (ARA), nutrients also found inbreast milk, that promote brain and eye development.

Breast milk is the standard for infant nutrition, and the American Academy ofPediatrics (AAP) recommends breastfeeding for most infants.2 According to theAAP, iron-fortified infant formula should be used if breastfeeding is not chosen,or is discontinued during the first year, or if a supplement to breast milk isdesired.3 Cow’s milk is not recommended for infants before their first birthday.

Long-Term Usage

Enfamil Gentlease is designed to provide the sole source of nutrition for infantsup to age 6 months and provide a major source of nutrition for the remainder ofthe first year. Normally, in feeding infants, gradual introduction of solid foodsafter 4–6 months of age is an important developmental as well as nutritionalstep. (See Table of Contents for other types of products appropriate for toddlersand children.)

PRODUCT FEATURES • Clinically proven to reduce fussiness and gas1,*

• A special blend of easy-to-digest proteins, patterned after the blend ofproteins found in breast milk,† that have been partially broken down

• A blend of carbohydrates with a reduced level of lactose‡ designed for babieswith fussiness or gas

• Includes our blend of DHA and ARA, nutrients also found in breast milk, that promotes brain and eye development4-11

*vs the same babies at the beginning of the study.†Comparison to whey:casein ratio of typical mature breast milk (15 days to 6 monthsafter birth).

‡Approximately 1/5 the lactose of a full-lactose, routine, milk-based formula.

24

NUTRIENTS§


Protein, g 2.3 11.8Fat, g 5.3 27


Carbohydrate, g 10.8 56Water, g 134 (Pwd) 2.6

133 (Liq)Vitamins/Other Nutrients


MineralsCalcium, mg 82 420Phosphorus, mg 46 240Magnesium, mg 8 41Iron, mg 1.8 9.3Zinc, mg 1 5.1Manganese, mcg 15 77Copper, mcg 75 390Iodine, mcg 15 77Selenium, mcg 2.8 14.4Sodium, mg 36 185Potassium, mg 108 560Chloride, mg 63 320Molybdenum, mcg NA NAChromium, mcg NA NA


NA=None Added

25

Enfam

il ®G

entlease®

NUTRIENT FACTSNutrient Density 20 Calories/fl ozProtein (% calories) 9Fat (% calories) 48Carbohydrate (% calories) 43Potential Renal Solute Load (mOsm/100 Calories)12 21Potential Renal Solute Load (mOsm/100 mL)12 14Osmolality (mOsm/kg water) 230 (Pwd)

220 (Liq)Osmolarity (mOsm/L) 210 (Pwd)

200 (Liq)Gluten-Free YesLactose-Free NoGalactose-Free|| No

||Not recommended for patients with galactosemia.

PRODUCT FORMSEnfamil® Gentlease® is available in powder and ready-to-use liquid. For orderinginformation, please refer to page 212.

COMPOSITIONIngredients: Powder: Corn syrup solids, partially hydrolyzed nonfat milk andwhey protein concentrate solids (soy), vegetable oil (palm olein, soy, coconut,and high oleic sunflower oils), and less than 2%: Mortierella alpina oil,¶

Crypthecodinium cohnii oil,# vitamin A palmitate, vitamin D3, vitamin E acetate,vitamin K1, thiamin hydrochloride, riboflavin, vitamin B6 hydrochloride, vitaminB12, niacinamide, folic acid, calcium pantothenate, biotin, ascorbic acid, cholinechloride, inositol, calcium carbonate, calcium phosphate, magnesium phosphate,ferrous sulfate, zinc sulfate, manganese sulfate, cupric sulfate, sodium hydroxide,potassium hydroxide, potassium chloride, sodium selenite, taurine, L-carnitine.

Ingredients: Ready to Use: Water, corn syrup solids, partially hydrolyzed nonfatmilk and whey protein concentrate solids (soy), vegetable oil (palm olein, soy,coconut, and high oleic sunflower oils), rice starch, and less than 1%: Mortierellaalpina oil,¶ Crypthecodinium cohnii oil,# vitamin B12, vitamin D3, ascorbic acid,vitamin E acetate, niacinamide, calcium pantothenate, vitamin A palmitate,riboflavin, thiamin hydrochloride, vitamin B6 hydrochloride, choline chloride,inositol, folic acid, vitamin K1, biotin, diacetyl tartaric esters of mono- anddiglycerides (datem), calcium carbonate, calcium phosphate, magnesiumchloride, ferrous sulfate, zinc sulfate, sodium citrate, cupric sulfate, manganesesulfate, potassium iodide, sodium selenite, taurine, L-carnitine.¶A source of arachidonic acid (ARA).#A source of docosahexaenoic acid (DHA).

POTENTIAL ALLERGENSEnfamil Gentlease contains milk and soy.

PREPARATION OF FEEDINGSThe baby’s health depends on carefully following these instructions. Properhygiene, preparation, dilution, use, and storage are important when

26

preparing infant formula. Powdered infant formulas are not sterile andshould not be fed to premature infants or infants who might have immuneproblems, unless directed and supervised by a doctor.

Discuss with parents whether they need to use cooled, boiled water for mixing andwhether they need to boil clean utensils, bottles, and nipples in water before use.

Powder





To Make** Water Powder Weight2 fl oz 2 fl oz 1 unpacked level scoop 8.7 g4 fl oz 4 fl oz 2 unpacked level scoops 17.4 g6 fl oz 6 fl oz 3 unpacked level scoops 26.1 g8 fl oz 8 fl oz 4 unpacked level scoops 34.8 g1 quart 28.5 fl oz 1 level household measuring 125 g

cup plus 2 level tablespoons of unpacked powder



Powder Storage


Nursette® Bottles







Store unopened bottles at room temperature. Avoid excessive heat and pro-longed exposure to light. Do not freeze. Use by date on carton and bottle label.

27

Enfam

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entlease®

CAUTION




REFERENCES1. Berseth CL, Mitmesser SH, Ziegler EE, Marunycz JD, Vanderhoof JA. Tolerance of a

standard intact protein formula versus a partially hydrolyzed formula in healthy, terminfants. Nutr J. 2009;8:27.

2. American Academy of Pediatrics, Section on Breastfeeding. Breastfeeding and theuse of human milk. Pediatrics. 2005;115:496-506.


4. Birch EE, Hoffman DR, Uauy RD, et al. Visual acuity and the essentiality ofdocosahexaenoic acid and arachidonic acid in the diet of term infants. Pediatr Res.1998;44:201-209.

5. Birch EE, Garfield S, Hoffman DR, et al. A randomized controlled trial of early dietarysupply of long-chain polyunsaturated fatty acids and mental development in terminfants. Dev Med Child Neurol. 2000;42:174-181.

6. Birch EE, Hoffman DR, Castañeda YS, et al. A randomized controlled trial of long-chain polyunsaturated fatty acid supplementation of formula in term infants afterweaning at 6 wk of age. Am J Clin Nutr. 2002;75:570-580.

7. Hoffman DR, Birch EE, Castañeda YS, et al. Maturation of visual and mental functionin 18-month old infants receiving dietary long-chain polyunsaturated fatty acids(LCPUFAs) [abstract]. FASEB J. 2003;17:A727-A728. Abstract 445.1.

8. Hoffman DR, Birch EE, Castañeda YS, et al. Visual function in breast-fed term infantsweaned to formula with or without long-chain polyunsaturates at 4 to 6 months: arandomized clinical trial. J Pediatr. 2003;142:669-677.

9. Hoffman DR, Birch EE, Birch DG, et al. Impact of early dietary intake and blood lipidcomposition of long-chain polyunsaturated fatty acids on later visual development.J Pediatr Gastroenterol Nutr. 2000;31:540-553.

10. Birch EE, Castañeda YS, Wheaton DH, et al. Visual maturation of term infants fedlong-chain polyunsaturated fatty acid-supplemented or control formula for 12 mo.Am J Clin Nutr. 2005;81:871-879.

11. Morale SE, Hoffman DR, Castañeda, YS, et al. Duration of long-chainpolyunsaturated fatty acids availability in the diet and visual acuity. Early Hum Dev.2005;81:197-203.



28

Enfamil A.R.®

For Spit Up

Thickened milk-based infant formula for the first 12 months

INDICATIONEnfamil A.R. is clinically proven* to reduce frequentspit up.

Breast milk is the standard for infant nutrition and the American Academy ofPediatrics (AAP) recommends breastfeeding for most infants.1 According to theAAP, iron-fortified infant formula should be used if breastfeeding is not chosen, is discontinued during the first year, or if a supplement to breast milk is desired.2

Cow’s milk is not recommended for infants before their first birthday.

Enfamil A.R. is the same formulation as Enfamil® RestFull™.*Studied before the addition of DHA and ARA in infants who regurgitate frequently (5 ormore regurgitations a day).

Long-Term Usage

Enfamil A.R. is designed to provide a sole source of nutrition for infants up toage 6 months, and provide a major source of nutrition until 12 months. Normally,in feeding infants, gradual introduction of solid foods after 4–6 months of age isan important developmental as well as nutritional step. (See Table of Contentsfor other types of products appropriate for toddlers and children.)

PRODUCT FEATURES • Clinically proven to reduce frequent spit up

• Nutritionally balanced with a nutrient profile similar to routine infant formula

• More nutritionally balanced than adding rice cereal to formula

• Viscosity in the bottle is 10 times that of routine formula,3 yet flows freelythrough a standard nipple

• Milk-based


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50

100

150

200

Enfamil®PREMIUM™

Cal

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Fat

Car

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Milk-basedFormula with

Rice Cereal Added

Cal

orie

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Car

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BalancedNutrition

Adding rice cereal compromises the nutritional balance12

Enfamil A.R.

Cal

orie

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Car

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Fat

29

Enfam

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.®

NUTRIENTS†


Protein, g 2.5 12.4Fat, g 5.1 25


Carbohydrate, g 11 55Water, g 134 2.6Vitamins/Other Nutrients



†Product nutrient values and ingredients are subject to change. Please see product labelfor current information.

NA=None Added

30

NUTRIENT FACTSNutrient Density 20 Calories/fl ozProtein (% calories) 10Fat (% calories) 46Carbohydrate (% calories) 44Potential Renal Solute Load (mOsm/100 Calories)13 22 (Liq)

23 (Pwd)Potential Renal Solute Load (mOsm/100 mL)13 15.1 (Liq)

15.3 (Pwd)Osmolality (mOsm/kg water) 240 (Liq)

230 (Pwd)Osmolarity (mOsm/L) 220 (Liq)

210 (Pwd)Gluten-Free YesLactose-Free NoGalactose-Free No

PRODUCT FORMSEnfamil A.R.® is available in powder and ready-to-use liquid. For orderinginformation, please refer to page 212.

COMPOSITIONIngredients: Powder: Nonfat milk, vegetable oil (palm olein, soy, coconut, andhigh oleic sunflower oils), rice starch, lactose, maltodextrin, and less than 2%:Mortierella alpina oil,‡ Crypthecodinium cohnii oil,§ vitamin A palmitate, vitaminD3, vitamin E acetate, vitamin K1, thiamin hydrochloride, riboflavin, vitamin B6

hydrochloride, vitamin B12, niacinamide, folic acid, calcium carbonate, calciumpantothenate, biotin, ascorbic acid, choline chloride, inositol, ferrous sulfate, zincsulfate, manganese sulfate, cupric sulfate, sodium selenite, sodium citrate,potassium hydroxide, taurine, L-carnitine.

Ingredients: Ready To Use: Water, nonfat milk, vegetable oil (palm olein, soy,coconut, and high oleic sunflower oils), lactose, rice starch, maltodextrin, and less than 1%: Mortierella alpina oil,‡ Crypthecodinium cohnii oil,§ mono- anddiglycerides, soy lecithin, carrageenan, vitamin A palmitate, vitamin D3, vitamin Eacetate, vitamin K1, thiamin hydrochloride, riboflavin, vitamin B6 hydrochloride,vitamin B12, niacinamide, folic acid, calcium carbonate, calcium pantothenate,biotin, ascorbic acid, choline chloride, inositol, ferrous sulfate, zinc sulfate,manganese sulfate, cupric sulfate, sodium selenite, sodium citrate, potassiumhydroxide, taurine, L-carnitine.‡A source of arachidonic acid (ARA).§A source of docosahexaenoic acid (DHA).

POTENTIAL ALLERGENSEnfamil A.R. contains milk and soy.

31

Enfam

il A.R

.®



Powder



3. Cap bottle and SHAKE WELL. Let bottle sit 5 minutes.


To Make|| Water Powder Weight2 fl oz 2 fl oz 1 unpacked level scoop 8.8 g4 fl oz 4 fl oz 2 unpacked level scoops 17.6 g6 fl oz 6 fl oz 3 unpacked level scoops 26.4 g8 fl oz 8 fl oz 4 unpacked level scoops 35.2 g1 quart 29 fl oz 11⁄3 unpacked level 129 g


||Each scoop adds about 0.2 fl oz to the amount of prepared formula.


Powder Storage

Store cans at room temperature. After opening can, keep tightly covered, storein dry area, and use contents within 1 month. Do not freeze powder. Avoidexcessive heat. Use by date on bottom of can.

Ready To Use





32



Nursette® Bottles








CAUTION




REFERENCES1. American Academy of Pediatrics, Section on Breastfeeding. Breastfeeding and the

use of human milk. Pediatrics. 2005;115:496-506.2. American Academy of Pediatrics, Committee on Nutrition. Iron fortification of infant

formulas. Pediatrics. 1999;104:119-123. Reaffirmed 11/02.3. Data on file, Mead Johnson Nutritionals, November 1996.4. Birch EE, Hoffman DR, Uauy RD, et al. Visual acuity and the essentiality of

docosahexaenoic acid and arachidonic acid in the diet of term infants. Pediatr Res.1998;44:201-209.






33

Enfam

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.®



12. Vanderhoof JA et al. Clin Pediatr. 2003;42:483-495.13. Fomon SJ, Ziegler EE. Renal solute load and potential renal solute in infancy.

J Pediatr. 1999;134:11-14.


34

Enfamil® ProSobee®

For Sensitive Tummies

Soy-based infant formula for the first 12 months

INDICATIONFor babies with sensitive tummies, when a soy formula is preferred.

Enfamil ProSobee is a soy protein isolate formula and is relied on for the routinefeeding of infants with feeding problems resulting from sensitivity to milk-basedformula. Enfamil ProSobee includes docosahexaenoic acid (DHA) andarachidonic acid (ARA), nutrients also found in breast milk, that promote brainand eye development. Enfamil ProSobee is a lactose-free and sucrose-free soyformula.

Breast milk is the standard for infant nutrition and the American Academy ofPediatrics (AAP) recommends breastfeeding for most infants.1 According to theAAP, iron-fortified infant formula should be used if breastfeeding is not chosen, isdiscontinued during the first year, or if a supplement to breast milk is desired.2


Long-Term Usage

Enfamil ProSobee is designed to provide a sole source of nutrition for infants up to age 6 months, and provide a major source of nutrition through 12 months of age when indicated. Normally, in feeding infants, gradual introduction of solid foods after 4–6 months of age is an important developmental as well asnutritional step. (See Table of Contents for other types of products appropriatefor toddlers and children.)

Although detrimental effects of prolonged use of Enfamil ProSobee as the solesource of diet beyond 6 months of age have not been reported, there is no basison which to recommend such a practice. Extended use of Enfamil ProSobee (orother infant formulas) as a sole source of diet is most appropriately monitored by physicians and nutritionists on a case-by-case basis, with attention todevelopmental as well as nutritional implications of such a dietary regimen.

PRODUCT FEATURES • Soy-based, milk-free, and lactose-free

• Often solves common feeding problems resulting from sensitivity to milk-based formula

• Sucrose (table sugar)-free—carbohydrate sweetness level similar to lactose, the major carbohydrate in breast milk3


35

Enfam

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Linoleic acid, mg 860 4300Linolenic acid, mg 85 (RTU) 400

80 (Pwd, Conc)DHA, mg 17 85ARA, mg 34 170

Carbohydrate, g 10.6 53Water, g 133 (Pwd, RTU) 2.7

134 (Conc)Vitamins/Other Nutrients

Vitamin A, IU 300 1500Vitamin D, IU 60 300Vitamin E, IU 2 10Vitamin K, mcg 8 (RTU) 45

9 (Pwd, Conc)Thiamin (Vitamin B1), mcg 80 400Riboflavin (Vitamin B2), mcg 90 450Vitamin B6, mcg 60 300Vitamin B12, mcg 0.3 1.5Niacin, mcg 1000 5000Folic acid (Folacin), mcg 16 80Pantothenic acid, mcg 500 2500Biotin, mcg 3 15Vitamin C (Ascorbic acid), mg 12 60Choline, mg 24 120Inositol, mg 6 30Carnitine, mg 2 10Taurine, mg 6 30

MineralsCalcium, mg 105 530Phosphorus, mg 69 350Magnesium, mg 11 (RTU) 40

8 (Pwd, Conc)Iron, mg 1.8 9Zinc, mg 1.2 6Manganese, mcg 25 125Copper, mcg 75 380Iodine, mcg 15 75Selenium, mcg 2.8 14Sodium, mg 36 180Potassium, mg 120 600Chloride, mg 80 400Molybdenum, mcg NA NAChromium, mcg NA NA


NA=None Added36

NUTRIENT FACTSNutrient Density 20 Calories/fl ozProtein (% calories) 10Fat (% calories) 48Carbohydrate (% calories) 42Potential Renal Solute Load (mOsm/100 Calories)12 23Potential Renal Solute Load (mOsm/100 mL)12 15.6Osmolality (mOsm/kg water) 170 (RTU, Conc)

180 (Pwd)Osmolarity (mOsm/L) 153 (RTU)

155 (Conc)162 (Pwd)

Gluten-Free YesLactose-Free YesGalactose-Free No

PRODUCT FORMSEnfamil® ProSobee® is available in powder, ready-to-use liquid, and concentrate.For ordering information, please refer to page 212.

COMPOSITIONIngredients: Powder: Corn syrup solids (55%), vegetable oil (palm olein, soy,coconut, and high oleic sunflower oils) (26%), soy protein isolate (14%), and lessthan 2%: Mortierella alpina oil,† Crypthecodinium cohnii oil,‡ vitamin A palmitate,vitamin D3, vitamin E acetate, vitamin K1, thiamin hydrochloride, riboflavin,vitamin B6 hydrochloride, vitamin B12, niacinamide, folic acid, calciumpantothenate, biotin, ascorbic acid, choline chloride, inositol, calcium carbonate,calcium phosphate, magnesium chloride, magnesium phosphate, ferrous sulfate,zinc sulfate, cupric sulfate, potassium iodide, sodium selenite, sodium citrate,potassium citrate, potassium hydroxide, potassium chloride, L-methionine,taurine, L-carnitine.

Ingredients: Ready To Use: Water (87%), corn syrup solids (7%), vegetable oil(palm olein, soy, coconut, and high oleic sunflower oils) (3%), soy protein isolate(2%), and less than 1%: Mortierella alpina oil,† Crypthecodinium cohnii oil,‡ mono-and diglycerides, soy lecithin, carrageenan, vitamin A palmitate, vitamin D3,vitamin E acetate, vitamin K1, thiamin hydrochloride, riboflavin, vitamin B6

hydrochloride, vitamin B12, niacinamide, folic acid, calcium pantothenate, biotin,sodium ascorbate, ascorbic acid,§ choline chloride, inositol, calcium carbonate,calcium phosphate, magnesium chloride, magnesium phosphate, ferrous sulfate,zinc sulfate, cupric sulfate, potassium iodide, sodium selenite, sodium chloride,potassium citrate, potassium hydroxide, potassium chloride, L-methionine,taurine, L-carnitine.†A source of arachidonic acid (ARA).‡A source of docosahexaenoic acid (DHA).§Ascorbic acid is only included in our 2 fl oz Nursette® bottles.

37

Enfam

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Ingredients: Concentrated Liquid: Water (75%), corn syrup solids (14%),vegetable oil (palm olein, soy, coconut, and high oleic sunflower oils) (6%), soyprotein isolate (4%), and less than 1%: Mortierella alpina oil,† Crypthecodiniumcohnii oil,‡ mono- and diglycerides, soy lecithin, carrageenan, vitamin Apalmitate, vitamin D3, vitamin E acetate, vitamin K1, thiamin hydrochloride,riboflavin, vitamin B6 hydrochloride, vitamin B12, niacinamide, folic acid, calciumpantothenate, biotin, ascorbic acid, choline chloride, inositol, calcium carbonate,calcium phosphate, magnesium chloride, magnesium phosphate, ferrous sulfate,zinc sulfate, cupric sulfate, potassium iodide, sodium selenite, sodium chloride,potassium citrate, potassium hydroxide, potassium chloride, L-methionine,taurine, L-carnitine.†A source of arachidonic acid (ARA).‡A source of docosahexaenoic acid (DHA).

POTENTIAL ALLERGENSEnfamil® ProSobee® contains soy.



Powder





To Make§ Water Powder Weight2 fl oz 2 fl oz 1 unpacked level scoop 8.9 g4 fl oz 4 fl oz 2 unpacked level scoops 17.8 g6 fl oz 6 fl oz 3 unpacked level scoops 26.7 g8 fl oz 8 fl oz 4 unpacked level scoops 35.6 g1 quart 28.5 fl oz 1 unpacked level 128 g




38

Powder Storage


Ready To Use







Nursette® Bottles








Concentrate



3. Pour desired amount of water into the bottle. Add an equal amount ofconcentrated liquid. Shake or stir well.


39

Enfam

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®

Concentrate Storage


CAUTION






formulas. Pediatrics. 1999;104:119-123. Reaffirmed 11/02.3. Data on file, Mead Johnson Nutritionals, April 2007.4. Birch EE, Hoffman DR, Uauy RD, et al. Visual acuity and the essentiality of











40

Nutramigen®

with Enflora™ LGG®*

For Colic Due to Protein Sensitivity*LGG is a registered trademark of Valio Ltd.

INDICATIONNutramigen with Enflora LGG is an iron-fortified, lactose-free, galactose-free,sucrose-free, hypoallergenic infant formula for term infants who are allergic tothe intact proteins in cow’s milk and soy formulas, as well as other foods.Nutramigen with Enflora LGG contains extensively hydrolyzed protein to avoidan immune system response, and the probiotic LGG to support healthy andnormal functioning of the GI tract. Nutramigen with Enflora LGG is alsoappropriate for infants with galactosemia.

Breast milk is the standard for infant nutrition and the American Academy ofPediatrics (AAP) recommends breastfeeding for most infants.1 According to theAAP, iron-fortified infant formula should be used if breastfeeding is not chosen, is discontinued during the first year, or if a supplement to breast milk is desired.2


Long-Term Usage

Nutramigen with Enflora LGG is designed to provide a sole source of nutritionfor infants up to age 6 months, and provide a major source of nutrition through12 months of age. Normally, in feeding infants, gradual introduction of solidfoods after 4–6 months of age is an important developmental as well asnutritional step.

In cases of severe and multiple food allergies or intolerances, Nutramigen withEnflora LGG is sometimes continued as a milk substitute in the diet of children.This and similar supplemental use of Nutramigen with Enflora LGG in the dietbeyond 12 months of age may make a significant contribution to maintenance of good nutrition in such patients. When Nutramigen is used as a milk substitute,the total calcium content of the diet should be assessed.

Although detrimental effects of prolonged use of Nutramigen as the sole sourceof diet beyond 6 months of age have not been reported, there is no basis onwhich to recommend such a practice. Extended use of Nutramigen with EnfloraLGG (or other infant formulas) as a sole source of diet is most appropriatelymonitored by physicians and nutritionists on a case-by-case basis, with attentionto developmental as well as nutritional implications of such a dietary regimen.

41

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LGG

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PRODUCT FEATURES• Hypoallergenic, lactose-free, galactose-free and sucrose-free

• Clinically proven to effectively manage colic due to cow’s milk protein allergy in48 hours†

• Contains the probiotic LGG, the most effective strain for infants with cow’s milkprotein allergy

• Proven to promote skin health in infants through 18 months of age3,†

• Proven to promote gastrointestinal (GI) health within 1 week of use4,†

• Includes our blend of DHA and ARA, nutrients also found in breast milk, thatpromotes brain and eye development5-12

• Fatty acid profile patterned after breast milk13,14,‡

†Studied before the addition of DHA, ARA and probiotics. ‡Comparison based on fatty acid profile of typical mature U.S. breast milk.

42

NUTRIENTS§


Protein, g 2.8 13.9Fat, g 5.3 26






NA=None Added

43

Nutram

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LGG

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NUTRIENT FACTSNutrient Density 20 Calories/fl ozProtein (% calories) 11Fat (% calories) 48Carbohydrate (% calories) 41Potential Renal Solute Load (mOsm/100 Calories)15 25Potential Renal Solute Load (mOsm/100 mL)15 16.8Osmolality (mOsm/kg water) 300Osmolarity (mOsm/L) 270Gluten-Free YesLactose-Free Yes Galactose-Free Yes

PRODUCT FORMNutramigen® with Enflora™ LGG® is available in powder. For orderinginformation, please refer to page 212.

COMPOSITIONIngredients: Powder: Corn syrup solids (45%), vegetable oil (palm olein, soy,coconut, and high oleic sunflower oils) (26%), casein hydrolysate (from milk)||

(17%), modified corn starch (7%), and less than 2%: Mortierella alpina oil,¶

Crypthecodinium cohnii oil,# Lactobacillus rhamnosus GG (LGG), vitamin Apalmitate, vitamin D3, vitamin E acetate, vitamin K1, thiamin hydrochloride,riboflavin, vitamin B6 hydrochloride, vitamin B12, niacinamide, folic acid, calciumpantothenate, biotin, ascorbic acid, choline chloride, inositol, calcium citrate,calcium hydroxide, calcium phosphate, magnesium oxide, ferrous sulfate, zincsulfate, manganese sulfate, cupric sulfate, sodium iodide, sodium selenite,sodium citrate, potassium citrate, potassium chloride, L-cystine, L-tyrosine,L-tryptophan, taurine, L-carnitine.||Modified to be better tolerated in milk-allergic babies.¶A source of arachidonic acid (ARA).#A source of docosahexaenoic acid (DHA).

POTENTIAL ALLERGENSNutramigen with Enflora LGG contains milk and soy. Nutramigen with EnfloraLGG is hypoallergenic. Allergic reactions to extensively hydrolyzed caseinformulas are not commonly reported.

PREPARATION OF FEEDINGS The baby’s health depends on carefully following these instructions. Properhygiene, preparation, dilution, use, and storage are important whenpreparing infant formula. Powdered infant formulas are not sterile andshould not be fed to premature infants or infants who might have immuneproblems, unless directed and supervised by a doctor.

Discuss with parents whether they need to use cooled, boiled water for mixing andwhether they need to boil clean utensils, bottles, and nipples in water before use.

Powder


2. Pour the desired amount of water into the bottle. The amount necessarydepends on the desired amount of formula. See following chart.

44

3. Mix powder formula with cool water (35–75°F); it should feel cool on yourwrist. Do not warm. Warming can limit benefits of LGG. Microwaving formulacan cause serious burns to baby.

NOTE: Never use hot tap water.

4. Shake for about 5 seconds.


To Make** Water Powder Weight2 fl oz bottle 2 fl oz 1 packed level scoop 9 g4 fl oz bottle 4 fl oz 2 packed level scoops 18 g6 fl oz bottle 6 fl oz 3 packed level scoops 27 g8 fl oz bottle 8 fl oz 4 packed level scoops 36 g1 quart 28.5 fl oz 11⁄3 packed level 129 g

household measuring cups


Failure to follow these instructions could result in severe harm. Onceprepared, infant formula can spoil quickly. Either immediately feed orimmediately cover and refrigerate at 35–40°F (2–4°C) for no longer than 24 hours.Do not use prepared formula if it is unrefrigerated for more than a total of 2hours. Do not freeze prepared formula. After feeding begins, do not refrigeratefeeding bottle. You must use within 1 hour or discard.

Powder Storage

Store cans at room temperature. After opening can, keep tightly covered, storein dry area, and use contents within 1 month. Do not freeze powder, and avoidexcessive heat. Use by date on bottom of can.

CAUTION

This product is not recommended for routine use in very low-birth-weight infants.Some of these infants may be at increased risk of developing gastrointestinalcomplications.

This information applies to products sold in the USA only. Formulations andmixing instructions for products sold outside the USA may vary. Refer to theinformation on the label of the product you are preparing.



use of human milk. Early Hum Dev. 2005;115:496-506.2. American Academy of Pediatrics, Committee on Nutrition. Iron fortification of infant

formulas. Early Hum Dev. 1999;104:119-123. Reaffirmed 11/02.3. Oldæus G, Anjou K, Björkstén B, et al. Extensively and partially hydrolysed infant

formulas for allergy prophylaxis. Arch Dis Child. 1997;77:4-10.4. Berezin S, Schwarz SM, Glassman M, et al. Gastrointestinal milk intolerance of

infancy. Am J Dis Child. 1989;143:361-362.5. Birch EE, Hoffman DR, Uauy RD, et al. Visual acuity and the essentiality of


45

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LGG

®




9. Hoffman DR, Birch EE, Castañeda YS, et al. Maturation of visual and mental functionin 18-month-old infants receiving dietary long-chain polyunsaturated fatty acids(LCPUFAs) [abstract]. FASEB J. 2003;17:A727-A728. Abstract 445.1.



12. Morale SE, Hoffman DR, Castañeda YS, et al. Duration of long-chain polyunsaturatedfatty acids availability in the diet and visual acuity. Early Hum Dev. 2005;81:197-203.

13. Innis SM. Human milk and formula fatty acids. J Pediatr. 1992;120(suppl): S56-S61.14. Jensen RG, ed. Handbook of Milk Composition. San Diego, Calif: Academic

Press;1995.15. Fomon SJ, Ziegler EE. Renal solute load and potential renal solute load in infancy.

J Pediatr. 1999;134:11-14.


46

Nutramigen®

(Liquids)For Colic Due to Cow’s Milk Protein Allergy

INDICATIONNutramigen is an iron-fortified, lactose-free, hypoallergenic infant formula forterm infants who are allergic to the intact proteins in cow’s milk and soy formulas,as well as other foods. Nutramigen contains extensively hydrolyzed proteinproven effective for managing colic due to cow’s milk protein allergy.

Breast milk is the standard for infant nutrition and the American Academy ofPediatrics (AAP) recommends breastfeeding for most infants.1 According to theAAP, iron-fortified infant formula should be used if breastfeeding is not chosen,is discontinued during the first year, or if a supplement to breast milk is desired.2


Long-Term Usage

Nutramigen is designed to provide a sole source of nutrition for infants up toage 6 months, and provide a major source of nutrition through 12 months ofage. Normally, in feeding infants, gradual introduction of solid foods after 4–6months of age is an important developmental as well as nutritional step.

In cases of severe and multiple food allergies or intolerances, Nutramigen issometimes continued as a milk substitute in the diet of children. This and similarsupplemental use of Nutramigen in the diet beyond 12 months of age may makea significant contribution to maintenance of good nutrition in such patients.When Nutramigen is used as a milk substitute, the total calcium content of thediet should be assessed.

Although detrimental effects of prolonged use of Nutramigen as the sole sourceof diet beyond 6 months of age have not been reported, there is no basis onwhich to recommend such a practice. Extended use of Nutramigen (or otherinfant formulas) as a sole source of diet is most appropriately monitored byphysicians and nutritionists on a case-by-case basis, with attention todevelopmental as well as nutritional implications of such a dietary regimen.

PRODUCT FEATURES • Hypoallergenic, lactose-free, and sucrose-free

• Clinically proven to effectively manage colic due to cow’s milk protein allergy in48 hours3,4,*

• Includes our blend of DHA and ARA, nutrients also found in breast milk thatpromotes brain and eye development5-12

• Fatty acid profile patterned after breast milk13,14,†

*Studied before the addition of DHA and ARA.†Comparison based on fatty acid profile of typical mature U.S. breast milk.

47

Nutram

igen

®(Liq

uids)

NUTRIENTS‡


Protein, g 2.8 13.9Fat, g 5.3 26

Linoleic acid, mg 860 4300Linolenic acid, mg 85 (Liq) 400DHA, mg 17 84ARA, mg 34 169


Vitamin A, IU 300 1490Vitamin D, IU 50 250Vitamin E, IU 2 9.9Vitamin K, mcg 8 (Liq) 45Thiamin (Vitamin B1), mcg 80 400Riboflavin (Vitamin B2), mcg 90 450Vitamin B6, mcg 60 300Vitamin B12, mcg 0.3 1.49Niacin, mcg 1000 5000Folic acid (Folacin), mcg 16 79Pantothenic acid, mcg 500 2500Biotin, mcg 3 14.9Vitamin C (Ascorbic acid), mg 12 60Choline, mg 24 119Inositol, mg 17 84Carnitine, mg 2 9.9Taurine, mg 6 30

MineralsCalcium, mg 94 470Phosphorus, mg 52 260Magnesium, mg 11 (Liq) 40Iron, mg 1.8 8.9Zinc, mg 1 5Manganese, mcg 25 124Copper, mcg 75 370Iodine, mcg 15 74Selenium, mcg 2.8 13.9Sodium, mg 47 230Potassium, mg 110 550Chloride, mg 86 430Molybdenum, mcg NA NAChromium, mcg NA NA

‡Product nutrient values and ingredients are subject to change. Please see product labelfor current information.

NA=None Added

48

NUTRIENT FACTSNutrient Density 20 Calories/fl ozProtein (% calories) 11Fat (% calories) 48Carbohydrate (% calories) 41Potential Renal Solute Load (mOsm/100 Calories)15 25Potential Renal Solute Load (mOsm/100 mL)15 16.8Osmolality (mOsm/kg water) 320 (2 fl oz)

260 (6 & 32 fl oz, conc)Osmolarity (mOsm/L) 290 (2 fl oz)

230 (6 & 32 fl oz, conc)Gluten-Free YesLactose-Free YesGalactose-Free Yes

PRODUCT FORMSNutramigen® is available in ready-to-use liquid and concentrate. For orderinginformation, please refer to page 212.

COMPOSITIONIngredients: Ready To Use 32 fl oz: Water (87%), corn syrup solids (5%),vegetable oil (palm olein, soy, coconut, and high oleic sunflower oils) (3%), caseinhydrolysate (from milk)§ (2%), modified corn starch (2%), and less than 1%:Mortierella alpina oil,|| Crypthecodinium cohnii oil,¶ acetylated monoglycerides,carrageenan, vitamin A palmitate, vitamin D3, vitamin E acetate, vitamin K1,thiamin hydrochloride, riboflavin, vitamin B6 hydrochloride, vitamin B12,niacinamide, folic acid, calcium pantothenate, biotin, ascorbic acid, cholinechloride, inositol, calcium carbonate, calcium phosphate, magnesium oxide,ferrous sulfate, zinc sulfate, manganese sulfate, cupric sulfate, sodium iodide,sodium selenite, sodium citrate, potassium citrate, potassium chloride, citric acid,taurine, L-cystine, L-tyrosine, L-tryptophan, L-carnitine.Ingredients: Ready To Use 2 fl oz: Water (85%), corn syrup solids (6%),vegetable oil (palm olein, soy, coconut, and high oleic sunflower oils) (3%), caseinhydrolysate (from milk)§ (2%), modified corn starch (2%), and less than 1%:Mortierella alpina oil,|| Crypthecodinium cohnii oil,¶ acetylated monoglycerides,carrageenan, vitamin A palmitate, vitamin D3, vitamin E acetate, vitamin K1,thiamin hydrochloride, riboflavin, vitamin B6 hydrochloride, vitamin B12,niacinamide, folic acid, calcium pantothenate, biotin, ascorbic acid, cholinechloride, inositol, calcium carbonate, calcium phosphate, magnesium oxide,ferrous sulfate, zinc sulfate, manganese sulfate, cupric sulfate, sodium iodide,sodium selenite, sodium citrate, potassium citrate, potassium chloride, citric acid,taurine, L-cystine, L-tyrosine, L-tryptophan, L-carnitine.§Modified to be better tolerated in milk-allergic babies.|| A source of arachidonic acid (ARA).¶A source of docosahexaenoic acid (DHA).

49

Nutram

igen

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uids)

Ingredients: Concentrated Liquid: Water (75%), corn syrup solids (10%),vegetable oil (palm olein, soy, coconut, and high oleic sunflower oils) (7%), caseinhydrolysate (from milk)§ (4%), modified corn starch (3%), and less than 1%:Mortierella alpina oil,|| Crypthecodinium cohnii oil,¶ acetylated monoglycerides,carrageenan, vitamin A palmitate, vitamin D3, vitamin E acetate, vitamin K1,thiamin hydrochloride, riboflavin, vitamin B6 hydrochloride, vitamin B12,niacinamide, folic acid, calcium pantothenate, biotin, ascorbic acid, cholinechloride, inositol, calcium carbonate, calcium phosphate, magnesium oxide,ferrous sulfate, zinc sulfate, manganese sulfate, cupric sulfate, sodium iodide,sodium selenite, sodium citrate, potassium citrate, potassium chloride, citric acid,taurine, L-cystine, L-tyrosine, L-tryptophan, L-carnitine.§Modified to be better tolerated in milk-allergic babies.|| A source of arachidonic acid (ARA).¶A source of docosahexaenoic acid (DHA).

POTENTIAL ALLERGENSNutramigen® contains milk and soy. Nutramigen is hypoallergenic. Rarely,however, allergic reactions to extensively hydrolyzed casein formulas have beenreported.

PREPARATION OF FEEDINGSThe baby’s health depends on carefully following these instructions. Properhygiene, preparation, dilution, use, and storage are important whenpreparing infant formula.


Ready To Use







Nutramigen does not look or taste like milk or soy formulas. It may separate inthe refrigerator. Shake well before feeding.

Nursette® Bottles




50





Concentrate



3. Pour desired amount of water into the bottle. Add an equal amount ofconcentrated liquid. Shake or stir well.


Concentrate Storage


CAUTION






formulas. Pediatrics. 1999;104:119-123. Reaffirmed 11/02.3. Lothe L, Lindberg T. Cow’s milk whey protein elicits symptoms of infantile colic in

colicky formula-fed infants: a double-blind crossover study. Pediatrics. 1989;83:262-266.

4. Lothe L, Lindberg T, Jakobsson I. Cow’s milk formula as a cause of infantile colic: adouble-blind study. Pediatrics. 1982;70:7-10.



51

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13. Innis SM. Human milk and formula fatty acids. J Pediatr. 1992;120(suppl):S56-S61.14. Jensen RG, ed. Handbook of Milk Composition. San Diego, Calif: Academic

Press;1995.15. Fomon SJ, Ziegler EE. Renal solute load and potential renal solute load in infancy.

J Pediatr. 1999;134:11-14.


52

Nutramigen® AA™

Hypoallergenic Amino Acid-Based Formula

INDICATIONNutramigen AA is an iron-fortified, hypoallergenic, amino acid-based infantformula for the dietary management of infants and toddlers with severe cow’smilk protein allergy, not effectively managed by an extensively hydrolyzedformula. Nutramigen AA is also indicated for the dietary management of infantsand toddlers with multiple food protein allergies.

Long-Term Usage

Nutramigen AA is designed to provide a sole source of nutrition for infants up to age 6 months and provide a major source of nutrition through 24 months ofage, when indicated. Normally, in feeding infants, gradual introduction of solidfoods after 4–6 months of age is an important developmental as well asnutritional step.

In cases of severe and multiple food allergies or intolerances, Nutramigen AA issometimes continued as a milk substitute in the diet of children. This and similarsupplemental use of Nutramigen AA in the diet beyond 24 months of age maymake a significant contribution to maintenance of good nutrition in suchpatients. When Nutramigen AA is used as a milk substitute, the total calciumcontent of the diet should be assessed.

Although detrimental effects of prolonged use of Nutramigen AA as the solesource of diet beyond 6 months of age have not been reported, there is no basison which to recommend such a practice. Extended use of Nutramigen AA (orother infant formulas) as a sole source of diet is most appropriately monitored by physicians and nutritionists on a case-by-case basis, with attention todevelopmental as well as nutritional implications of such a dietary regimen.

PRODUCT FEATURES • Hypoallergenic

• Nutritionally complete

– Can be sole source of nutrition up to age 6 months

– Can be major source of nutrition through 24 months.

– Dietary reference intakes include a recommendation for fiber for >12months of age

• Iron fortified


• 2.8 g protein equivalent/100 Calories

53

Nutram

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A™

NUTRIENTS*(Normal Dilution ) Per 100 Per 100 grams

Calories (5 fl oz) Powder (510 Cal)Protein equivalent, g 2.8 14.3Carbohydrate, g 10.3 53Water, g 133 2.4Fat, g 5.3 27


Vitamins/Other NutrientsVitamin A, IU 300 1530Vitamin D, IU 50 260Vitamin E, IU 2 10.2Vitamin K, mcg 8 41Thiamin (Vitamin B1), mcg 80 410Riboflavin (Vitamin B2), mcg 90 460Vitamin B6, mcg 60 310Vitamin B12, mcg 0.3 1.53Niacin, mcg 1000 5100Folic acid (Folacin), mcg 16 82Pantothenic acid, mcg 500 2600Biotin, mcg 3 15.3Vitamin C (Ascorbic acid), mg 12 61Choline, mg 24 123Inositol, mg 17 87Carnitine, mg 2 10.2Taurine, mg 6 31

MineralsCalcium, mg 94 480Phosphorus, mg 52 270Magnesium, mg 11 56Iron, mg 1.8 9.2Zinc, mg 1 5.1Manganese, mcg 60 310Copper, mcg 75 380Iodine, mcg 15 77Selenium, mcg 2.8 14.3Sodium, mg 47 240Potassium, mg 110 560Chloride, mg 86 440Molybdenum, mcg NA NAChromium, mcg NA NA


NA=None Added

54

NUTRIENT FACTS Nutrient Density 20 Calories/fl ozProtein (% calories) 11Fat (% calories) 48Carbohydrate (% calories) 41Potential Renal Solute Load (mOsm/100 Calories)11 25Potential Renal Solute Load (mOsm/100 mL)11 16.8Osmolality (mOsm/kg water) 350Osmolarity (mOsm/L) 320Gluten-Free YesLactose-Free YesGalactose-Free Yes

PRODUCT FORM Nutramigen® AA™ is available in powder. For ordering information, please referto page 212.

COMPOSITION Ingredients: Powder: Corn syrup solids (46%), vegetable oil (palm olein, soy,coconut, and high oleic sunflower oils) (26%), amino acids (L-cystine, L-histidine,L-isoleucine, L-leucine, L-methionine, L-phenylalanine, L-threonine, L-tryptophan,L-tyrosine, L-valine, lysine hydrochloride, monosodium glutamate, L-alanine,L-arginine, L-aspartic acid, L-proline, L-serine, glycine) (17%), modified tapiocastarch (5%), and less than 2%: Mortierella alpina oil,† Crypthecodinium cohnii oil,‡

vitamin A palmitate, vitamin D3, vitamin E acetate, vitamin K1, thiamin hydro-chloride, riboflavin, vitamin B6 hydrochloride, vitamin B12, niacinamide, folic acid,calcium pantothenate, biotin, ascorbic acid, choline chloride, inositol, calciumcitrate, calcium hydroxide, calcium phosphate, magnesium oxide, ferrous sulfate,zinc sulfate, manganese sulfate, cupric sulfate, sodium iodide, sodium selenite,sodium citrate, potassium citrate, potassium chloride, taurine, L-carnitine.†A source of arachidonic acid (ARA).‡A source of docosahexaenoic acid (DHA).

POTENTIAL ALLERGENS Nutramigen AA contains soy oil. Nutramigen AA is hypoallergenic.


Discuss with parents whether they need to use cooled, boiled water for mixingand whether they need to boil clean utensils, bottles, and nipples in water before use.

55

Nutram

igen

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A™

Powder


2. Pour the desired amount of water into the bottle. The amount necessarydepends on the desired amount of formula. See following chart.

3. Mix powder formula with cool water (35–75ºF); it should feel cool on your wrist.If you prefer, you may mix with warm water, but only if you feed or refrigeratethe formula immediately. Warm water is about 100ºF or body temperature; itshould feel neutral (neither warm nor cool) on your wrist.

NOTE: Never use hot tap water.

4. Shake for about 5 seconds.


To Make§ Water Powder Weight1 fl oz 1 fl oz 1 unpacked level scoop 4.5 g2 fl oz 2 fl oz 2 unpacked level scoops 9 g4 fl oz 4 fl oz 4 unpacked level scoops 18 g8 fl oz 8 fl oz 8 unpacked level scoops 36 g1 quart 28.5 fl oz 1 unpacked level 129 g

household measuring cupplus 2 unpacked level Tbsps

§Each scoop adds about 0.1 fl oz to the amount of prepared formula. For example,adding 3 unpacked level scoops of powder to 3 fl oz of water will make about 3.3 fl ozof formula.

Failure to follow these instructions could result in severe harm. Onceprepared, infant formula can spoil quickly. Either feed immediately or store inthe refrigerator at 35–40°F (2–4°C) for no longer than 24 hours. Do not useprepared formula if it is unrefrigerated for more than a total of 2 hours. Do notfreeze prepared formula. After feeding begins, do not refrigerate a partially usedfeeding bottle. You must use within 1 hour or discard.

Powder Storage

Store cans at room temperature. After opening the can, keep it tightly covered,store in a dry area, and use the contents within 1 month. Do not freeze powder,and avoid excessive heat. Use by date on bottom of can.

CAUTION

Use product by the date on the container.






formulas. Pediatrics. 1999;104:119-123. Reaffirmed 11/02.

56





7. Hoffman DR, Birch EE, Castañeda YS, et al. Maturation of visual and mental functionin 18-month-old infants receiving dietary long-chain polyunsaturated fatty acids(LCPUFAs) [abstract]. FASEB J. 2003;17: A727-A728. Abstract 445.1.


9. Fomon SJ, Ziegler EE. Renal solute and potential renal solute load in infancy.J Pediatr. 1999;134:11–14.


57

Nutram

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A™

Pregestimil®For Fat Malabsorption Problems

INDICATIONPregestimil is designed for infants who experience fat malabsorption and whomay also be sensitive to intact proteins. Fat malabsorption or steatorrhea may be associated with cystic fibrosis, short bowel syndrome, intractable diarrhea,and severe protein calorie malnutrition. Pregestimil is also appropriate for infantswith galactosemia.

Long-Term Usage

Pregestimil is designed to provide a sole source of nutrition for infants up to age 6 months, and to provide a major source of nutrition through 12 months of age.Normally, in feeding infants, gradual introduction of solid foods after 4–6 months of age is an important developmental as well as nutritional step.

In cases of chronic malabsorption disorders, Pregestimil is sometimes continued as a milk substitute in the diet of children. This and similar supplemental use ofPregestimil in the diet beyond 12 months of age may make a significant contri-bution to the maintenance of good nutrition in such patients, and is not known to be harmful in any way. When Pregestimil is used as a milk substitute, the totalcalcium content of the diet should be assessed.

Although detrimental effects of prolonged use of Pregestimil as the sole sourceof diet beyond 6 months of age have not been reported, there is no basis onwhich to recommend such a practice. Extended use of Pregestimil (or otherinfant formulas) as a sole source of diet is most appropriately monitored byphysicians and nutritionists on a case-by-case basis, with attention todevelopmental as well as nutritional implications of such a dietary regimen.

PRODUCT FEATURES • Hypoallergenic, lactose-free, and sucrose-free

• 55% of the fat from MCT oil

• Designed for infants with fat malabsorption problems

• Ready to use is virtually isotonic


• Available in both powder and Nursette® bottles

NUTRIENT VALUES FOR VARIOUS FORMSForm Cal Pro Fat Carb Cal Pro Fat Carb

per 100 mL per fl ozNursette Bottle – 20 Cal/floz 68 1.89g 3.8g 6.9g 20 0.56g 1.12g 2gNursette Bottle – 24 Cal/floz 81 2.3g 4.5g 8.3g 24 0.67g 1.34g 2.4g

per 100 g per scoop (8.9g)Powder 500 14g 28g 51g 45 1.25g 2.5g 4.5g

58

NUTRIENTS*(Normal Dilution) Per 100 Per 100

Calories grams20 Cal/fl oz 24 Cal/fl oz Powder

RTU & Pwd (5 fl oz) RTU (4.2 fl oz)Protein, g 2.8 2.8 14Fat, g 5.6 5.6 28

Linoleic acid, mg 940 940 4700Linolenic acid, mg 120 (RTU) 120 480

95 (Pwd)DHA, mg 17 17 85ARA, mg 34 34 170

Carbohydrate, g 10.2 10.2 51Water, g 133 (RTU) 108

131 (Pwd) 2.6Vitamins/Other Nutrients

Vitamin A, IU 380 (RTU) 380 1750350 (Pwd)

Vitamin D, IU 50 50 250Vitamin E, IU 4 4 20Vitamin K, mcg 12 12 60Thiamin (Vitamin B1), mcg 80 80 400Riboflavin (Vitamin B2), mcg 90 90 450Vitamin B6, mcg 60 60 300Vitamin B12, mcg 0.3 0.3 1.5Niacin, mcg 1000 1000 5000Folic acid (Folacin), mcg 16 16 80Pantothenic acid, mcg 500 500 2500Biotin, mcg 3 3 15Vitamin C (Ascorbic acid), mg 12 12 60Choline, mg 24 24 120Inositol, mg 17 17 85Carnitine, mg 2 2 10Taurine, mg 6 6 30

MineralsCalcium, mg 94 94 470Phosphorus, mg 52 52 260Magnesium, mg 11 (RTU) 11 40

8 (Pwd)Iron, mg 1.8 1.8 9Zinc, mg 1 1 5Manganese, mcg 25 25 125Copper, mcg 75 75 380Iodine, mcg 15 15 75Selenium, mcg 2.8 2.8 14Sodium, mg 47 47 240Potassium, mg 110 110 550Chloride, mg 86 86 430Molybdenum, mcg NA NA NAChromium, mcg NA NA NA


NA=None Added59

Preg

estimil ®

NUTRIENT FACTS

Nutrient Density 20 Calories/fl oz 24 Calories/fl ozProtein (% calories) 11 11Fat (% calories) 48 48Carbohydrate (% calories) 41 41Potential Renal Solute Load

(mOsm/100 Calories)9 25 25Potential Renal Solute Load

(mOsm/100 mL)9 16.8 20Osmolality 290 (RTU) 340

(mOsm/kg water) 320 (Pwd)Osmolarity 260 (RTU) 300

(mOsm/L) 280 (Pwd)Gluten-Free Yes YesLactose-Free Yes YesGalactose-Free Yes Yes

PRODUCT FORMSPregestimil® is available in powder and ready-to-use liquid. For orderinginformation, please refer to page 212.

COMPOSITIONIngredients: Powder: Corn syrup solids (42%), casein hydrolysate (from milk)†

(16%), medium-chain triglycerides (MCT) oil (15%), modified corn starch (7%), soyoil (7%), corn oil (2%), high oleic vegetable oil (safflower or sunflower) (2%), andless than 2%: Mortierella alpina oil,‡ Crypthecodinium cohnii oil,§ vitamin Apalmitate, vitamin D3, vitamin E acetate, vitamin K1, thiamin hydrochloride,riboflavin, vitamin B6 hydrochloride, vitamin B12, niacinamide, folic acid, calciumpantothenate, biotin, ascorbic acid, choline chloride, inositol, calcium citrate,calcium phosphate, magnesium oxide, ferrous sulfate, zinc sulfate, manganesesulfate, cupric sulfate, sodium iodide, sodium citrate, potassium citrate,potassium chloride, potassium hydroxide, sodium selenite, L-cystine, L-tyrosine,L-tryptophan, taurine, L-carnitine.

Ingredients: 20 Calories/fl oz Ready To Use: Water (87%), corn syrup solids(5%), casein hydrolysate (from milk)† (2%), medium-chain triglycerides (MCT) oil(2%), and less than 2%: modified corn starch, soy oil, high oleic vegetable oil(safflower and/or sunflower oils), Mortierella alpina oil,‡ Crypthecodinium cohniioil,§ carrageenan, vitamin A palmitate, vitamin D3, vitamin E acetate, vitamin K1,thiamin hydrochloride, riboflavin, vitamin B6 hydrochloride, vitamin B12,niacinamide, folic acid, calcium pantothenate, biotin, ascorbic acid, cholinechloride, inositol, calcium carbonate, calcium hydroxide, calcium phosphate,potassium phosphate, magnesium chloride, ferrous sulfate, zinc sulfate,manganese sulfate, cupric sulfate, sodium iodide, potassium citrate, sodiumselenite, L-cystine, L-tyrosine, L-tryptophan, taurine, L-carnitine.†Modified to be better tolerated in milk-allergic babies.‡A source of arachidonic acid (ARA).§A source of docosahexaenoic acid (DHA).

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Ingredients: 24 Calories/fl oz Ready To Use: Water (85%), corn syrup solids(6%), casein hydrolysate (from milk)† (3%), medium-chain triglycerides (MCT) oil(2%), modified corn starch (2%), and less than 2%: soy oil, high oleic vegetable oil(safflower and/or sunflower oils), Mortierella alpina oil,‡ Crypthecodinium cohniioil,§ carrageenan, vitamin A palmitate, vitamin D3, vitamin E acetate, vitamin K1,thiamin hydrochloride, riboflavin, vitamin B6 hydrochloride, vitamin B12,niacinamide, folic acid, calcium pantothenate, biotin, ascorbic acid, cholinechloride, inositol, calcium carbonate, calcium hydroxide, calcium phosphate,potassium phosphate, magnesium chloride, ferrous sulfate, zinc sulfate,manganese sulfate, cupric sulfate, sodium iodide, potassium citrate, sodiumselenite, L-cystine, L-tyrosine, L-tryptophan, taurine, L-carnitine.†Modified to be better tolerated in milk-allergic babies.‡A source of arachidonic acid (ARA).§A source of docosahexaenoic acid (DHA).

POTENTIAL ALLERGENSPregestimil® contains milk and soy. Pregestimil is hypoallergenic. Rarely, however,allergic reactions to extensively hydrolyzed casein formulas have been reported.

PREPARATION OF FEEDINGSThe baby’s health depends on carefully following these instructions. Useonly as directed by a medical professional. Proper hygiene, preparation,dilution, use, and storage are important when preparing infant formula.Powdered infant formulas are not sterile and should not be fed topremature infants or infants who might have immune problems unlessdirected and supervised by a doctor.


Powder



3. Cap bottle and shake well.


To Make|| Water Powder Weight2 fl oz 2 fl oz 1 packed level scoop 8.9 g4 fl oz 4 fl oz 2 packed level scoops 17.8 g6 fl oz 6 fl oz 3 packed level scoops 26.7 g8 fl oz 8 fl oz 4 packed level scoops 35.6 g1 quart 29 fl oz 1 packed level 128 g



Failure to follow these instructions could result in severe harm. Onceprepared, infant formula can spoil quickly. Either feed immediately or coverand store in refrigerator at 35–40°F (2–4°C) for no longer than 24 hours. Do notuse prepared formula if it is unrefrigerated for more than a total of 2 hours. Do

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not freeze prepared formula. After feeding begins, do not refrigerate feedingbottle; you must use within 1 hour or discard.

Powder Storage

Store cans at room temperature. After opening can, keep tightly covered, storein dry area, and use contents within 1 month. Do not freeze powder and avoidexcessive heat.

Use by date on bottom of can. Pregestimil® does not look or taste like milk orsoy formulas. It may separate in the refrigerator. Shake well before feeding.

Nursette® Bottles







Store unopened bottles at room temperature. Avoid excessive heat andprolonged exposure to light. Do not freeze. Use by date on carton and bottlelabel. Pregestimil does not look or taste like milk or soy formulas. It may separatein the refrigerator. Shake well before feeding. Use product by date on container.

CAUTION

Use product by the date on the container.




REFERENCES1. Birch EE, Hoffman DR, Uauy RD, et al. Visual acuity and the essentiality of





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9. Fomon SJ, Ziegler EE. Renal solute and potential renal solute load in infancy.J Pediatr. 1999;134:11–14.


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Enfamil® PrematureMilk-based Infant Formula for Premature or Low-Birth-Weight Infants

INDICATIONEnfamil Premature is specifically formulated to meet the unique nutritional needsof rapidly growing premature or low-birth-weight infants who do not receivehuman milk.

When more than 12 oz (355 mL) of 24 Calories/fl oz product is used per day,which may occur in larger infants weighing over 2500 g (5.5 lbs) consuming onlyEnfamil Premature, intake of some nutrients (eg, fat soluble vitamins) may beexcessive. In such circumstances, it should be used only at the direction andunder the supervision of a doctor. Enfamil® EnfaCare® may be a product toconsider in such circumstances.

PRODUCT FEATURES • 3 g of protein/100 Calories—appropriate level for growth and development1-3

• Levels of calcium, phosphorus, and vitamin D within the ranges recommendedby experts for bone mineralization and growth1-3


• Includes medium-chain triglycerides (MCT) oil to promote fat absorption12,13

• Free nucleotide levels patterned after breast milk14-17

NUTRIENT VALUES FOR VARIOUS FORMSCaloric Density Grams/100 mL Grams/fl oz(Calories/fl oz) (undiluted) (undiluted)

Form Cal Pro Fat Carb Cal Pro Fat Carb

Nursette® Bottle 20 68 2 3.4 7.4 20 0.6 1.02 2.2

Nursette Bottle 24 81 2.4 4.1 8.9 24 0.72 1.22 2.6

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NUTRIENTS†

(Normal Dilution) 20 Calories/fl oz 24 Calories/fl ozPer 100 Calories Per 100 Calories

(5 fl oz) (4.2 fl oz)Protein, g 3 3Fat, g 5.1 5.1


Carbohydrate, g 11 11Water, g 133 108

Vitamins/Other NutrientsVitamin A, IU 1250 1250Vitamin D, IU 240 240Vitamin E, IU 6.3‡ 6.3‡

Vitamin K, mcg 8 8Thiamin (Vitamin B1), mcg 200 200Riboflavin (Vitamin B2), mcg 300 300Vitamin B6, mcg 150 150Vitamin B12, mcg 0.25 0.25Niacin, mcg 4000 4000Folic acid (Folacin), mcg 40 40Pantothenic acid, mcg 1200 1200Biotin, mcg 4 4Vitamin C (Ascorbic acid), mg 20 20Choline, mg 20 20Inositol, mg 44 44Carnitine, mg 2.4 2.4Taurine, mg 6 6

MineralsCalcium, mg 165 165Phosphorus, mg 83 83Magnesium, mg 9 9Iron, mg‡ 0.5(1.8)§ 0.5(1.8)§

Zinc, mg 1.5 1.5Manganese, mcg 6.3 6.3Copper, mcg 120 120Iodine, mcg 25 25Selenium, mcg 2.8 2.8Sodium, mg 58 58Potassium, mg 98 98Chloride, mg 90 90Molybdenum, mcg 0.4|| 0.4||

Chromium, mcg 0.2|| 0.2||


‡Supplemental vitamin E and iron (when using Low Iron) should also be considered forthe premature infant.

§Numbers in parentheses are iron-fortified levels.|| None added. Naturally occurring.

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NUTRIENT FACTSNutrient Density 20 Calories/fl oz 24 Calories/fl ozProtein (% calories) 12 12Fat (% calories) 44 44Carbohydrate (% calories) 44 44Potential Renal Solute Load

(mOsm/100 Calories)18 27 27Potential Renal Solute Load

(mOsm/100 mL)18 18.4 22Osmolality (mOsm/kg water) 240 300Osmolarity (mOsm/L) 220 260Gluten-Free Yes YesLactose-Free No NoGalactose-Free No No

PRODUCT FORMEnfamil® Premature is available in ready-to-use Nursette® bottles. For orderinginformation, please refer to page 212.

COMPOSITIONIngredients: Ready To Use: Water, nonfat milk, corn syrup solids, lactose,medium-chain triglycerides (MCT) oil, whey protein concentrate, soy oil, higholeic vegetable oil (sunflower and/or safflower) and less than 0.5%: Mortierellaalpina oil,¶ Crypthecodinium cohnii oil,# mono- and diglycerides, carrageenan,vitamin A palmitate, vitamin D3, vitamin E acetate, vitamin K1, thiaminhydrochloride, riboflavin, vitamin B6 hydrochloride, vitamin B12, niacinamide, folicacid, calcium pantothenate, biotin, sodium ascorbate, choline chloride, inositol,calcium carbonate, calcium chloride, calcium hydroxide, calcium phosphate,magnesium phosphate, ferrous sulfate, zinc sulfate, cupric sulfate, potassiumiodide, sodium citrate, sodium chloride, potassium citrate, taurine, L-carnitine,nucleotides (adenosine 5’-monophosphate, cytidine 5’-monophosphate,disodium guanosine 5’-monophosphate, disodium uridine 5’-monophosphate).¶A source of arachidonic acid (ARA).#A source of docosahexaenoic acid (DHA).

POTENTIAL ALLERGENSEnfamil Premature contains milk and soy.



Nursette Bottles



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Enfamil® Premature may be provided at full strength or diluted for initialfeedings. If it is diluted, progression to full strength should be made rapidly, astolerated. If Enfamil Premature formula is fed to very low-birth-weight infants orstressed low-birth-weight infants, some clinicians choose to dilute initial feedingsto half strength (12 Calories/fl oz if 24 Calories/fl oz formula is used; 10 Calories/floz if 20 Calories/fl oz formula is used).

20 Calories/fl oz FormulationDilution (parts of formula to parts of water)

PRSL18 Protein Osmolality OsmolarityCalories/mL Calories/fl oz (mOsm/ (g/100 mL) (mOsm/kg (mOsm/L)

100 mL) of water)

1:1 0.34 10 9.1 1 114 110

Full strength 0.68 20 18.1 2 240 220

24 Calories/fl oz FormulationDilution (parts of formula to parts of water)

PRSL18 Protein Osmolality OsmolarityCalories/mL Calories/fl oz (mOsm/ (g/100 mL) (mOsm/kg (mOsm/L)

100 mL) of water)

1:1 0.41 12 11 1.2 140 130

3:1 0.61 18 16.5 1.8 220 200

Full strength 0.81 24 22 2.4 300 260

PRSL (mOsm/100 mL) = (mmole nitrogen/2 + mmole Na + mmole K + mmole Cl +mmole P)/100 mL.

Nursette® Bottle Storage

Store unopened bottles at room temperature. Avoid excessive heat andprolonged exposure to light. Do not freeze. Use by date on carton and bottle label.

WARNING: Do not use a microwave oven to warm formula. Serious burns mayresult.

REFERENCES1. Klein CJ. Nutrient requirements for preterm infant formulas. J Nutr. 2002;132(suppl):

1395S-1577S.2. Health Canada. Guidelines for the composition and clinical testing of formulas for

preterm infants: Report of an ad hoc expert consultation to the Health ProtectionBranch. Ottawa, Canada: Minister of Supplies and Services, 1995.

3. Tsang RC, Uauy RD, Koletzko B, Zlotkin SH, eds. Nutrition of the Preterm Infant:Scientific Basis and Practical Guidelines. 2nd ed. Cincinnati, Ohio: Digital EducationalPublishing Inc; 2005.

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12. Tantibhedhyangkul P, Hashim SA. Medium-chain triglyceride feeding in prematureinfants: effects on fat and nitrogen absorption. Pediatrics. 1975;55:359-370.

13. Andrews BF, Lorch V. Improved fat and Ca absorption in LBW infants fed a medium-chain triglyceride containing formula [abstract]. Pediatr Res. 1974;8:104.

14. Leach JL, Baxter JH, Molitor BE, et al. Total potentially available nucleosides ofhuman milk by stage of lactation. Am J Clin Nutr. 1995;61:1224-1230.

15. Sugawara M, Sato N, Nakano T, et al. Profile of nucleotides and nucleosides ofhuman milk. J Nutr Sci Vitaminol (Tokyo). 1995;41:409-418.

16. Thorell L, Sjöberg L-B, Hernell O. Nucleotides in human milk: sources andmetabolism by the newborn infant. Pediatr Res. 1996;40:845-852.

17. Data on file, Mead Johnson Nutritionals, March 1998.18. Fomon SJ, Ziegler EE. Renal solute load and potential renal solute load in infancy.

J Pediatr. 1999;134:11-14.


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Enfamil® EnfaCare®

Milk-based, 22-Calorie Discharge Formula forBabies Who Were Born Prematurely

INDICATIONEnfamil EnfaCare is designed with extra amounts of important nutrients for the nutritional management of infants who were born prematurely or with low birth weight. It is typically used for infants from approximately 1800 grams in weight and is typically recommended until 9 to 12 months of age.

PRODUCT FEATURES • 22 Calories/fluid ounce

• Higher levels of some vitamins and minerals than found in Enfamil with DHAand ARA to meet the needs of infants with conditions such as prematurity orlow birth weight

• 2.8 g protein/100 Calories, which is a higher protein level than Enfamil withDHA and ARA


• 20% of the fat blend from medium-chain triglycerides (MCT) oil

• Free nucleotide levels patterned after human milk

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NUTRIENTS*(Normal Dilution) Per 100 Per 100 grams

Calories (4.5 fl oz) Powder (490 Cal)Protein, g 2.8 13.8Fat, g 5.3 26

Linoleic acid, mg 950 (Liq) 4200860 (Pwd)

Linolenic acid, mg 95 470DHA, mg 17 84ARA, mg 34 168

Carbohydrate, g 10.4 51Water, g 120 (Liq) 2.6

117 (Pwd)Vitamins/Other Nutrients

Vitamin A, IU 450 2200Vitamin D, IU 70 350Vitamin E, IU 4 20Vitamin K, mcg 8 39Thiamin (Vitamin B1), mcg 200 990Riboflavin (Vitamin B2), mcg 200 990Vitamin B6, mcg 100 (Liq) 300

60 (Pwd)Vitamin B12, mcg 0.3 1.48Niacin, mcg 2000 (Liq) 4900

1000 (Pwd)Folic acid (Folacin), mcg 26 128Pantothenic acid, mcg 850 4200Biotin, mcg 6 (Liq) 25

5 (Pwd)Vitamin C (Ascorbic acid), mg 16 79Choline, mg 24 118Inositol, mg 30 148Carnitine, mg 2 9.9Taurine, mg 6 30

MineralsCalcium, mg 120 590Phosphorus, mg 66 330Magnesium, mg 8 39Iron, mg 1.8 8.9Zinc, mg 1.25 (Liq) 4.9

1 (Pwd)Manganese, mcg 15 74Copper, mcg 120 590Iodine, mcg 21 104Selenium, mcg 2.8 13.8Sodium, mg 35 (Liq) 182

37 (Pwd)Potassium, mg 105 520Chloride, mg 78 380Molybdenum, mcg NA NAChromium, mcg NA NA


NA=None Added71

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NUTRIENT FACTSNutrient Density 22 Calories/fl ozProtein (% calories) 11Fat (% calories) 47Carbohydrate (% calories) 42Potential Renal Solute Load (mOsm/100 Calories)9 25Potential Renal Solute Load (mOsm/100 mL)9 18.3 (Liq)

18.4 (Pwd)Osmolality (mOsm/kg water) 250 (Liq)

310 (Pwd)Osmolarity (mOsm/L) 220 (Liq)

270 (Pwd)Gluten-Free YesLactose-Free NoGalactose-Free No

PRODUCT FORMSEnfamil® EnfaCare® is available in powder, ready-to-use liquid, and Nursette®

bottles. For ordering information, please refer to page 212.

COMPOSITIONIngredients: Powder: Nonfat milk, whey protein concentrate, corn syrup solids,lactose, high oleic vegetable oil (sunflower and/or safflower oil), soy oil, medium-chain triglycerides (MCT) oil, coconut oil, and less than 2%: Mortierella alpina oil,†

Crypthecodinium cohnii oil,‡ vitamin A palmitate, vitamin D3, vitamin E acetate,vitamin K1, thiamin hydrochloride, riboflavin, vitamin B6 hydrochloride, vitaminB12, niacinamide, folic acid, calcium pantothenate, biotin, ascorbic acid, cholinechloride, inositol, calcium carbonate, calcium phosphate, magnesium chloride,ferrous sulfate, zinc sulfate, manganese sulfate, cupric sulfate, potassium iodide,sodium selenite, sodium chloride, potassium citrate, potassium hydroxide,taurine, L-carnitine, nucleotides (adenosine 5’-monophosphate, cytidine5’-monophosphate, disodium guanosine 5’-monophosphate, disodium uridine5’-monophosphate).

Ingredients: Ready To Use: Water, nonfat milk, maltodextrin, lactose, wheyprotein concentrate, high oleic vegetable oil (sunflower and/or safflower oil), soy oil, medium-chain triglycerides (MCT) oil, coconut oil, and less than 0.5%:Mortierella alpina oil,† Crypthecodinium cohnii oil,‡ mono- and diglycerides, soy lecithin, carrageenan, vitamin A palmitate, vitamin D3, vitamin E acetate,vitamin K1, thiamin hydrochloride, riboflavin, vitamin B6 hydrochloride, vitaminB12, niacinamide, folic acid, calcium pantothenate, biotin, sodium ascorbate,ascorbic acid, choline chloride, inositol, calcium chloride, calcium citrate, calciumhydroxide, calcium phosphate, magnesium chloride, ferrous sulfate, zinc sulfate,manganese sulfate, cupric sulfate, potassium iodide, sodium selenite, sodiumcitrate, potassium citrate, taurine, L-carnitine, nucleotides (adenosine5’-monophosphate, cytidine 5’-monophosphate, disodium guanosine5’-monophosphate, disodium uridine 5’-monophosphate).†A source of arachidonic acid (ARA).‡A source of docosahexaenoic acid (DHA).

72

POTENTIAL ALLERGENSEnfamil® EnfaCare® contains milk and soy.

PREPARATION OF FEEDINGSThe baby’s health depends on carefully following these instructions. Useonly as directed by a medical professional. Improper hygiene, preparation,dilution, use, or storage may result in severe harm. Although this powder isformulated for premature infants, powdered infant formulas are not sterileand should not be fed to premature infants or infants who might haveimmune problems unless directed and supervised by a doctor.


Powder





To Make§ Water Powder Weight2 fl oz 2 fl oz 1 unpacked level scoop 9.8 g4 fl oz 4 fl oz 2 unpacked level scoops 19.6 g6 fl oz 6 fl oz 3 unpacked level scoops 29.4 g8 fl oz 8 fl oz 4 unpacked level scoops 39.2 g1 quart 28.5 fl oz 11⁄4 unpacked level 142 g




Powder Storage


Ready To Use




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Nursette® Bottles








CAUTION










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9. Fomon SJ, Ziegler EE. Renal solute load and potential renal solute in infancy.J Pediatr. 1999;134:11-14.


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Enfamil® Human Milk FortifierNutritional Supplement to be Added to Expressed Breast Milk for Premature or Low-Birth-Weight Infants

INDICATIONEnfamil Human Milk Fortifier is to be added to expressed breast milk for feedingpremature or low-birth-weight infants. It provides enriched nutrition needed bythese special babies while still allowing them to receive their mother’s milk.Enfamil Human Milk Fortifier is milk-based and, when mixed with mother’s milk,increases the levels of protein, energy, calcium, phosphorus, and other nutrients,producing a diet more suited to the nutritional needs of the rapidly growingpremature infant.

Enfamil Human Milk Fortifier was specifically designed to be used as asupplement to be added to mother’s milk collected after 2 weeks postpartum.

PRODUCT FEATURES • Well tolerated

• 1.1 g protein/4 packets

• Added iron to reduce the need for additional iron supplementation

• Includes fat and essential fatty acids

• Low osmolality

76

NUTRIENTS*(Normal Dilution) Per 4–0.025 oz (0.71 g)

Packets (14 Cal)Protein, g 1.1Fat, g 1

Linoleic acid, mg 140Linolenic acid, mg 17

Carbohydrate, g < 0.4Water, g 0.09

Vitamins/Other NutrientsVitamin A, IU 950Vitamin D, IU 150Vitamin E, IU 4.6Vitamin K, mcg 4.4Thiamin (Vitamin B1), mcg 150Riboflavin (Vitamin B2), mcg 220Vitamin B6, mcg 115Vitamin B12, mcg 0.18Niacin, mcg 3000Folic acid (Folacin), mcg 25Pantothenic acid, mcg 730Biotin, mcg 2.7Vitamin C (Ascorbic acid), mg 12Choline, mg NAInositol, mg NACarnitine, mg NATaurine, mg NA

MineralsCalcium, mg 90Phosphorus, mg 50Magnesium, mg 1Iron, mg 1.44Zinc, mg 0.72Manganese, mcg 10Copper, mcg 44Iodine, mcg NASelenium, mcg NASodium, mg 16Potassium, mg 29Chloride, mg 13Molybdenum, mcg NAChromium, mcg NA


NA=None Added

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NUTRIENT FACTSNutrient Density Per 4 packets (14 Cal)Protein (% calories) 32Fat (% calories) 62Carbohydrate (% calories) 6Potential Renal Solute Load (mOsm/100 Calories)1 70Potential Renal Solute Load (mOsm/100 mL)1 9.8 per 4 packets†

Osmolality (mOsm/kg water)‡ +35Osmolarity (mOsm/L)‡ Not availableGluten-Free YesLactose-Free NoGalactose-Free No

†24 mOsm/102mL when 4 packets added to 100 mL preterm human milk.‡When added to human milk as recommended, EHMF increases osmolality byapproximately 35 mOsm/kg water.

PRODUCT FORMEnfamil® Human Milk Fortifier is available in powder. For ordering information,please refer to page 214.

COMPOSITIONIngredients: Powder: Medium-chain triglycerides (MCT) oil, milk protein isolate,whey protein isolate hydrolysate, soybean oil, calcium phosphate, calciumglycerophosphate, calcium gluconate, and less than 2%: corn syrup solids, soylecithin, vitamin A palmitate, vitamin D3, vitamin E acetate, vitamin K1, thiaminhydrochloride, riboflavin, vitamin B6 hydrochloride, vitamin B12, niacinamide, folicacid, calcium pantothenate, biotin, ascorbic acid, magnesium phosphate,potassium phosphate, ferrous sulfate, zinc sulfate, cupric sulfate, sodium citrate,potassium chloride, potassium citrate.

POTENTIAL ALLERGENSEnfamil Human Milk Fortifier contains milk and soy.

PREPARATION OF FEEDINGSThe baby’s health depends on carefully following these instructions. Useonly as directed by a medical professional. Improper hygiene, preparation,dilution, use, or storage may result in severe harm. Although this powder isformulated for premature infants, nutritional powders are not sterile andshould not be fed to premature infants or infants who might have immuneproblems unless directed and supervised by a doctor.

Follow hospital rules for the safe handling of human milk.

To aid mixing, agitate the human milk well. Pour the desired amount into asterile container and warm to feeding temperature.

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Add the powder to the human milk according to the following chart:Additional Enfamil®

Calories Desired Human Milk Human Milk Fortifier2 Calories/fl oz 50 mL 1 packet4 Calories/fl oz 25 mL 1 packet

Failure to follow these instructions could result in severe harm. Onceprepared, fortified breast milk can spoil quickly. Either feed fortified humanmilk immediately or cover and store in refrigerator at 35–40°F (2–4°C) for nolonger than 24 hours. Agitate before each use.

For tube feeding: Once fortified human milk is prepared it can safely remain atroom temperature for 4 hours.2 The American Dietetic Association recommendsa hang time for fortified breast milk of no longer than 4 hours at roomtemperature (25°C/77°F).3

For bottle feeding: Pour only the amount of fortified human milk to be fed intoa feeding container and feed immediately. Do not use fortified human milk if it isunrefrigerated for more than a total of 2 hours. After feeding begins, do notrefrigerate feeding bottle. You must use within 1 hour or discard.

Suggestions When Using This Product:

1. Monitor and regularly assess blood levels such as serum calcium, sodium, ureanitrogen, albumin, and others. In case of an elevated level, reduce the amountof Enfamil® Human Milk Fortifier used to supplement breast milk. In case ofdeficiency, additional supplementation with the deficient nutrient may beindicated.

2. Do not administer other nutrient supplements in addition to Enfamil HumanMilk Fortifier unless appropriate tests indicate a need for furthersupplementation with a particular nutrient.

3. Do not add Enfamil Human Milk Fortifier to breast milk in a ratio greater than1 packet/25 mL.

4. Preterm breast milk collected less than 2 weeks postpartum is particularly richin nutrients, so fortification with Enfamil Human Milk Fortifier is generally notrequired.

If more than 25 packets daily are used, the infant should be monitored forevidence of excessive vitamins A and D intake.

Powder Storage

Store Enfamil Human Milk Fortifier powder at room temperature. Avoid freezingand excessive heat. Use by date on package.

CAUTION

Not nutritionally complete. To be used only under the supervision ofa physician.

Neither expressed human milk nor nutritional powders are sterile.

WARNING: Do not use a microwave oven to prepare or warm fortified humanmilk. Serious burns may result.

Use only as directed. Improper dilution, preparation, handling, or storage maybe harmful.

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Regarding use in extremely low-birth-weight infants (ELBW–1 kg or less):Hypercalcemia has been reported in some of these infants on full enteral feedsof mothers’ milk supplemented with human milk fortifiers.

REFERENCES1. Fomon SJ, Ziegler EE. Renal solute load and potential renal solute in infancy.

J Pediatr. 1999;134:11-14.2. Telang S, Berseth CL, Ferguson PW, et al. Fortifying fresh human milk with

commercial powdered milk fortifiers does not affect bacterial growth during 6 hoursat room temperature. J Am Diet Assoc. 2005;105:1567-1572.

3. American Dietetic Association. Robbins ST, Beker LT, eds. Infant Feedings:Guidelines for Preparation of Formula and Breastmilk in Health Care Facilities.Chicago, Ill: American Dietetic Association; 2004:91.


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Hospital Feeding Systems

Hospital Feeding SystemsNURSETTE® BOTTLESProduct in vacuum-sealed, disposable, Nursette bottles for oral/enteral feeding iscommercially sterile and convenient. Nursette bottles are designed to be used withEnfamil® ready-to-use (40 mm) screw-type disposable nipple units described below.

NURSETTE BOTTLES AVAILABLE Disposable 2 fl oz bottles, conveniently packed, 48 per case. The bottles are madeof polypropylene and carry the #5 recycling code. The bottles are latex-free.

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Enfamil®24 Cal/fl oz

#138801

Enfamil®Gentlease®

20 Cal/fl oz#146401

Enfamil®ProSobee®

20 Cal/fl oz#144901

Nutramigen®

20 Cal/fl oz#143701

Pregestimil®20 Cal/fl oz

#143301

Enfamil A.R.®

20 Cal/fl oz#145301

Same formulation asEnfamil® RestFull™.

Enfamil®EnfaCare®

22 Cal/fl oz #139001

Enfamil® PrematureLow Iron

20 Cal/fl oz #139401

Enfamil®Premature

Iron Fortified 20 Cal/fl oz

#139201

Enfamil®Premature Low Iron

24 Cal/fl oz #139101

Enfamil®Premature

Iron Fortified24 Cal/fl oz

#139301

Enfamil®5% Glucose

Water#134601

Enfamil®Water forOral Use#134501

Pregestimil®24 Cal/fl oz

#143401

Enfamil®PREMIUM™

20 Cal/fl oz#136601

Disposable 6 fl oz bottles conveniently packed, 24 per case.

ENFAMIL® NIPPLESEnfamil Nipples are designed to be used with Nursette® bottles. Five differentnipples are available. All are ready to use and disposable. Nipples are packaged240 per case. Enfamil Nipples are made of surgical-grade plastic and are latex-free. The NUK® nipple contains latex.

Consumers may purchase nipples, in quantities of 6, by calling the toll-freenumber (1-800-BABY123).NUK is a registered trademark of MAPA, Germany.

PREPARATION OF FEEDINGSUsing Nursette Bottles and Enfamil Nipples

To assemble Nursette bottle units:

• Wash hands according to hospital procedures.

• Place bottles and nipple units on a clean work surface designated specificallyfor formula preparation.

• Inspect bottle to insure integrity of seal and unit; inspect nipple unit to insureintegrity of package.

• Shake bottle well.

• Twist cap on bottle to loosen but do not remove cap.

• Remove sealed bottom cover from nipple unit.

• Remove cap from bottle and twist on nipple collar until tight.

• The soft cover may be used to help protect the nipple until the baby is fed.

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EnfamilStandard-Flow Soft

Nipple#428816

Enfamil Slow-Flow Soft

Nipple#433905

Enfamil Cross-Cut

Nipple#428813

EnfamilNeonatalNipple

#420202

NUKNewborn

OrthodonticNipple

#210502

Enfamil®ProSobee®

20 Cal/fl oz#026106

Nutramigen®

20 Cal/fl oz#026306

Enfamil® Enfalyte®

Oral Electrolyte Solution #026506

Enfamil®PREMIUM™

20 Cal/fl oz#145801

To place an order, contact your Mead Johnson representative, or call Customer Service at 1-800-457-3550.

Failure to follow these instructions could result in severe harm. Openedbottles can spoil quickly. Either feed immediately or replace cap and store inrefrigerator at 35–40°F (2–4°C) for no longer than 48 hours. Hospital guidelineslimit refrigerated storage time to 24 hours. Do not use opened bottle if it isunrefrigerated for more than a total of 2 hours. (See page 229 for tube feedinghang times.) Do not freeze. After feeding begins, do not refrigerate feedingbottle. You must use within 1 hour or discard.

Nursette® Bottle Storage

Store unopened bottles at room temperature. Avoid excessive heat andprolonged exposure to light. Do not freeze. Use by date on carton and bottle label.

CAUTION



For information about preparation and feeding of infant formulas in healthcarefacilities, see the book: Robbins ST, Becker LT, eds. Infant Feedings: Guidelinesfor Preparation of Formula and Breastmilk in Health Care Facilities. Chicago, Ill:American Dietetic Association; 2004.

FEEDING BOTTLESMead Johnson distributes plastic bottles,Snappies™ Breast Milk Storage Containers,Grad-U-Feed® Nursers and Cleft Lip/PalateNursers. All are ready to use and disposable.All are latex-free and BPA-free.

Plastic Bottles

Convenient plastic bottles hold 8 fl oz andcome complete with an Enfamil® Standard-Flow Soft nipple, a nipple collar, and a nipplecover. The bottles are made of polypropyleneand are latex-free. There are 48 bottles ineach case.

Snappies Breast Milk Storage Containers

Snappies are 70 mL or 2.3 fl oz breast milkstorage containers with sterile interiors.Snappies are designed as one piece. The flip-top cap is conveniently hinged to theSnappies container so it can be opened and closed with one hand. The bottles are designed to collect, store, and feedexpressed breast milk. The bottles canwithstand freezing temperatures as low as minus 70° F.

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70 mL Snappies Breast Milk

Storage Containers200/case#134801

Ready-To-Use Plastic Bottles 48/case

#028401

Grad-U-Feed® Nurser

The Grad-U-Feed Nurser holds 60 mL offeeding and is used to feed small amounts toinfants in neonatal intensive care nurseries.The Grad-U-Feed Nurser is not designed tostore breast milk. The nursers are made ofpolypropylene and are latex-free. Nipple unitsare not provided with Grad-U-Feed Nursers.Enfamil® Nipples may be used. There are 100Grad-U-Feed Nursers per case.

Grad-U-Feed® Caps

These white plastic caps are designed to fit the Grad-U-Feed Nurser. They must besterilized before use and are designed to be used one time only. There are 750 caps per case.

Cleft Lip/Palate Nurser

The Cleft Lip/Palate Nurser is a squeezablebottle that holds 6 fl oz. It comes with anelongated nipple designed for babies with acleft lip or cleft palate. The nurser is made oflow-density polyethylene and is latex-free. Thenipple is made of surgical-grade plastic and islatex-free. There are 72 Cleft Lip/PalateNursers per case.

Consumers may purchase the Cleft Lip/PalateNurser, in quantities of 6, by calling the toll-free number (1-800-BABY123).

PACIFIERSThe NUK® Newborn Orthodontic Pacifier-Exerciser is available in quantities of 100 pacifiers per case. This pacifier does contain latex. NUK is a registered trademark of MAPA, Germany.

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Ho

spital Feed

ing System

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Grad-U-Feed Nurser 100/case#033901

Cleft Lip/PalateNurser72/case#200101

Grad-U-Feed Caps750/case#006802

Nuk Newborn Orthodontic

Pacifier-Exerciser #210702


HOSPITAL GIFTSCreated for both breastfeeding and formula-feeding moms, the Enfamil® Carryallis customized with helpful resources and offers tailored to the feeding methodmom chooses. The Enfamil Carryall is unique and reusable and environmentallyfriendly.

ENFAMIL CARRYALL HOSPITAL GIFTFormula-Feeding

Enfamil® PREMIUM™ Formula-Feeding Hospital Gift #300672

Enfamil® EnfaCare® Formula-Feeding Hospital Gift #300678

Enfamil® ProSobee® Formula-Feeding Hospital Gift #300676

Enfamil® PREMIUM™ Liquid Formula-Feeding Hospital Gift #300673

Enfamil® Gentlease® Formula-Feeding Hospital Gift #869335

Breastfeeding

Enfamil® PREMIUM™ Deluxe Breastfeeding Hospital Gift #300677

Enfamil® PREMIUM™ Breastfeeding Hospital Gift #300671

Spanish

Enfamil® PREMIUM™ Formula-Feeding Spanish Hospital Gift #300675


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Oral Electrolyte

Enfamil® Enfalyte®

Fruit-flavored, Oral Electrolyte Maintenance Solution

INDICATIONEnfamil Enfalyte is designed to be fed to infants and children for themaintenance of water and electrolytes that might otherwise be lost duringvomiting and diarrhea.

PRODUCT FEATURES • Carbohydrate from rice syrup solids to help replace the electrolytes and water

one might lose from vomiting and diarrhea

• Ready to use; no mixing or dilution required

• Made with natural fruit flavor

• Balanced levels of electrolytes not found in soft drinks and juices

• Low osmolality (170 mOsm/kg water)

• Lactose-free

PRODUCT FORMEnfamil Enfalyte is available in ready-to-use 6 fl oz Nursette® bottles. For orderinginformation, please refer to page 214.

COMPOSITION*Per 100 mL

mEq mgSodium 5 115Potassium 2.5 98Chloride 4.5 160

Rice Syrup Solids 3g per 100 mLCalories 126 Calories per LCitrates 34 mEq per L

Ingredients: Water, rice syrup solids, natural fruit flavors, salt (sodium chloride),potassium citrate, sodium citrate, citric acid.*Formulation changes coming in 2010. Please reference enfamilprofessional.com formore information.

ADMINISTRATIONYoung children or those with other underlying conditions, febrile children,children with dysentery (blood or mucus in stools), significant diarrhea orpersistent vomiting, and a caregiver’s report of signs and symptoms of

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dehydration or a change in mental status should have a medical evaluation tocheck for other serious conditions presenting with diarrhea, and to rule outconditions where oral rehydration would be contraindicated.

For Infants and Young Children

In 2004, the American Academy of Pediatrics (AAP) endorsed1 the Centers forDisease Control and Prevention’s report2 that children and nursing infants whohave diarrhea and who are not dehydrated, should continue to be fed age-appropriate diets. The dietary management of dehydration in children weighingless than 10 kg (22 pounds) with minimal dehydration includes replacement ofongoing losses with 2–4 fl oz of oral rehydration fluids for each watery stool or foreach episode of vomiting; larger children should be given twice as much. Thedietary management of children with mild or moderate dehydration shouldinclude replacement of their estimated fluid deficit within 2–4 hours using 50–100mL per kilogram of weight, in addition to replacement for ongoing losses.Physicians should guide parents on appropriate intakes based on the weight,rate of fluid loss, and clinical status of the infant.

Nursing infants should continue nursing on demand. Formula-fed infants whorequire rehydration should be fed age-appropriate diets as soon as they havebeen rehydrated. Lactose-free diets are rarely necessary following diarrhea.

For Older Children and Adults

Enfamil® Enfalyte® is recommended for all ages of children and adults. Older children and adults should continue their normal diet during episodes of diarrhea.

Intake should be adjusted on the basis of clinical indications, amount of fluidloss, patients’ usual water intake, and other relevant factors.

Enfamil Enfalyte in Conjunction with Other Fluids

When severe fluid losses or accumulated deficits require parenteral fluid therapy,Enfamil Enfalyte may be given orally while the infant, child, or adult is alsoreceiving parenteral therapy to supply part of the estimated fluid needs. Carefulattention must be paid to the amount of Enfamil Enfalyte consumed as itcontributes to the total fluid intake. After emergency needs have been met,Enfamil Enfalyte alone (orally) may be used. Once the patient can tolerateregular foods, they may be introduced and the amount of Enfamil Enfalytecorrespondingly decreased.

METHOD OF ADMINISTRATIONEnfamil Enfalyte may be fed to infants from a bottle with nipple or a spoon, andto children and adults from a cup, spoon, or straw. The calculated fluid deficientshould be given in the first 2–4 hours. Ongoing losses should be replaced asthey occur.

The baby’s health depends on carefully following these directions.

Examine the bottle for signs of damage. For home use, discuss with parents theneed to boil nipple assembly in water.

Remove cap and attach nipple unit (not included), or pour into clean feeding cup.

After opening, feed immediately, or cover and refrigerate Enfamil Enfalyte andfeed within 48 hours. Throw away remaining Enfamil Enfalyte in feeding bottle orcup within 1 hour after feeding begins. Store unopened bottles at roomtemperature. Avoid excessive heat. Do not freeze.

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CAUTION


Urgent needs due to severe fluid imbalances must be met parenterally.

Discontinue Enfamil® Enfalyte® when diarrhea has ceased.

WARNING: Do not use a microwave oven to warm product. Serious burns may result.

Not for parenteral (I.V.) use.

Enfamil Enfalyte is not nutritionally complete. Additional breast milk, formula,and/or food should be given as directed by the physician. The AAP endorses1

the Centers of Disease Control and Prevention’s report2 that children and nursinginfants who have diarrhea and who are not dehydrated should continue to befed age-appropriate diets. Children who require rehydration should be fed age-appropriate diets as soon as they have been rehydrated.

Enfamil Enfalyte should not be used in the presence of severe, persistentdiarrhea, intractable vomiting, adynamic ileus, intestinal obstruction, orperforated bowel.

REFERENCES1. American Academy of Pediatrics. Managing acute gastroenteritis among children:

oral rehydration, maintenance, and nutritional therapy. Pediatrics. 2004;114:507.2. King CK, Glass R, Bresee JS, et al. for the Centers for Disease Control and

Prevention. MMWR Recomm Rep. 2003;52(RR-16):1-16. Available at:http://www.cdc.gov/mmwr/PDF/RR/RR5216.pdf. Accessed November 19, 2006.


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Toddler Formulas

Enfagrow™ PREMIUM™

NEXT STEP®

Milk-based Formula for Infants and Toddlers10–36 Months

INDICATIONEnfagrow PREMIUM NEXT STEP is a milk-based formula for infants or toddlers10–36 months who are transitioning from infant formula or breast milk. EnfagrowPREMIUM NEXT STEP with Triple Health Guard™ provides a strong nutritionalfoundation for a toddler during a critical time of development. It has as muchcalcium and vitamin D as whole milk for toddlers.

According to the American Academy of Pediatrics (AAP), iron-fortified infantformula should be used if breastfeeding is not chosen, is discontinued during thefirst year, or if a supplement to breast milk is desired.1 Cow’s milk is notrecommended before the first birthday.

PRODUCT FEATURES• Includes our blend of DHA and ARA, nutrients also found in breast milk,

that promotes brain and eye development2-9

• Includes iron to support mental development

• Includes vitamins C and E to support the immune system

• Includes as much calcium and vitamin D as whole milk10 to support bonedevelopment

• Includes other key nutrients like zinc that are important for toddlerdevelopment

• Sucrose-free

• No artificial sweeteners

• No artificial flavoring

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Vitamin A, IU 300 1520Vitamin D, IU 60 300Vitamin E, IU 2 10.1Vitamin K, mcg 8 40Thiamin (Vitamin B1), mcg 80 400Riboflavin (Vitamin B2), mcg 140 710Vitamin B6, mcg 60 300Vitamin B12, mcg 0.3 1.52Niacin, mcg 1000 5100Folic acid (Folacin), mcg 16 81Pantothenic acid, mcg 500 2500Biotin, mcg 3 15.2Vitamin C (Ascorbic acid), mg 12 61Choline, mg 24 121Inositol, mg 6 30

MineralsCalcium, mg 195 980Phosphorus, mg 130 660Magnesium, mg 8 40Iron, mg 2 10.1Zinc, mg 1 5.1Manganese, mcg 15 76Copper, mcg 75 380Iodine, mcg 10 51Selenium, mcg 2.8 14.1Sodium, mg 36 182Potassium, mg 130 660Chloride, mg 80 400


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NUTRIENT FACTS Nutrient Density 20 Calories/fl ozProtein (% calories) 10Fat (% calories) 48Carbohydrate (% calories) 42Potential Renal Solute Load (mOsm/100 Calories)11 26Potential Renal Solute Load (mOsm/100 mL)11 17.7Osmolality (mOsm/kg water) 270Osmolarity (mOsm/L) 240Gluten-Free YesLactose-Free NoGalactose-Free No

PRODUCT FORMS Enfagrow™ PREMIUM™ NEXT STEP® is available in powder and ready-to-usecans. For ordering information, please see page 214.

COMPOSITIONIngredients: Powder: Nonfat milk, vegetable oil (palm olein, soy, coconut, andhigh oleic sunflower oils), corn syrup solids, lactose, calcium phosphate, and lessthan 1%: Mortierella alpina oil,† Crypthecodinium cohnii oil,‡ vitamin A palmitate,vitamin D3, vitamin E acetate, vitamin K1, thiamin hydrochloride, riboflavin,vitamin B6 hydrochloride, vitamin B12, niacinamide, folic acid, calciumpantothenate, biotin, ascorbic acid, choline chloride, inositol, ferrous sulfate, zincsulfate, manganese sulfate, cupric sulfate, sodium selenite, potassium chloride,potassium hydroxide, taurine, L-carnitine.

Ingredients: Ready To Use: Water, nonfat milk, vegetable oil (palm olein, soy,coconut, and high oleic sunflower oils), corn syrup solids, lactose, and less than1%: Mortierella alpina oil,† Crypthecodinium cohnii oil,‡ milk protein isolate,mono- and diglycerides, soy lecithin, carrageenan, vitamin A palmitate, vitaminD3, vitamin E acetate, vitamin K1, thiamin hydrochloride, riboflavin, vitamin B6

hydrochloride, vitamin B12, niacinamide, folic acid, calcium pantothenate, biotin,sodium ascorbate, ascorbic acid, choline chloride, inositol, calcium hydroxide,calcium phosphate, ferrous sulfate, zinc sulfate, manganese sulfate, cupricsulfate, sodium selenite, potassium chloride, potassium citrate, potassiumhydroxide, taurine, L-carnitine.†A source of arachidonic acid (ARA).‡A source of docosahexaenoic acid (DHA).

POTENTIAL ALLERGENS Enfagrow PREMIUM NEXT STEP contains milk and soy.

PREPARATION OF FEEDINGSThe baby’s health depends on carefully following these instructions. Properhygiene, preparation, dilution, use, and storage are important whenpreparing formula.


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Powder


2. Pour desired amount of water into bottle or cup. Add powder.

3. Cap bottle or cup and SHAKE WELL.

Use the following chart for correct amounts of water and powder. Use the scoopin the can to measure powder. Store the DRY scoop in its original can.

Powder (use scoop insideTo Make§ Water can to measure powder) Weight6 fl oz bottle 6 fl oz 3 unpacked level scoops 26.4 g8 fl oz bottle 8 fl oz 4 unpacked level scoops 35.2 g1 quart 29 fl oz 11⁄3 unpacked level 127 g



Failure to follow these instructions could result in severe harm. Once prepared,formula can spoil quickly. Either feed immediately or cover and store in therefrigerator at 35–40°F (2–4°C) for no longer than 48 hours. Do not use preparedformula if it is unrefrigerated for more than a total of 2 hours. Do not freezeprepared formula. After feeding begins, do not refrigerate feeding bottle; youmust use within 1 hour or discard.

Powder Storage

Store cans at room temperature. After opening the can, keep it tightly covered,store in dry area, and use the contents within 1 month. Do not freeze powder.

Ready To Use

1. Wash hands thoroughly with soap and water before preparing feeding bottles.


3. Pour the desired amount of formula into the bottle. DO NOT ADD WATER.

4. Attach the nipples, rings, and discs or nipple covers.

5. Failure to follow these instructions could result in severe harm. Opened cansand prepared bottles can spoil quickly. Either feed immediately or cover andstore in refrigerator at 35-40°F (2–4°C) for no longer than 48 hours. Do not useopened can and/or prepared bottle if they are unrefrigerated for more than atotal of 2 hours. Do not freeze prepared bottle.

After feeding begins, do not refrigerate feeding bottle. You must use within 1hour or discard.


Store unopened cans at room temperature. Avoid excessive heat. Do not freeze.

Use by date on top of can.

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CAUTION




REFERENCES 1. American Academy of Pediatrics, Committee on Nutrition. Iron fortification of infant

formulas. Pediatrics. 1999;104:119-123. Reaffirmed 11/02.2. Birch EE, Hoffman DR, Uauy RD, et al. Visual acuity and the essentiality of









10. U.S. Department of Agriculture, Agricultural Research Service. 2006. USDA NationalNutrient Database for Standard Reference, Release 19. [database online]. Availableat: http://www.nal.usda.gov/fnic/foodcomp/search. Accessed September 29, 2006.



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Enfagrow™ Soy NEXT STEP®

Soy-based Formula for Infants and Toddlers10–36 Months

INDICATIONEnfagrow Soy NEXT STEP is a soy-based formula for infants or toddlers 10–36months who are transitioning from infant formula or breast milk. Enfagrow SoyNEXT STEP with Triple Health Guard™ provides a strong nutritional foundationfor your toddler during a critical time of development. It has as much calciumand vitamin D as whole milk for toddlers.

Soy-based formulas, such as Enfagrow Soy NEXT STEP with Triple Health Guard,are appropriate for use in infants with lactose intolerance and galactosemia, andmost infants with IgE-mediated allergy to cow’s milk protein.1

According to the American Academy of Pediatrics (AAP), iron-fortified infantformula should be used if breastfeeding is not chosen, is discontinued during the first year, or if a supplement to breast milk is desired.2 Cow’s milk is notrecommended before the first birthday.

PRODUCT FEATURES • Includes our blend of DHA and ARA, nutrients also found in breast milk,

that promotes brain and eye development3-10

• Includes iron to support mental development

• Includes vitamins C and E to support the immune system

• Includes as much calcium and vitamin D as whole milk11 to support bonedevelopment


• Lactose-free

• Sucrose-free

• Milk-free

• No artificial sweeteners

• No artificial flavoring

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Vitamin A, IU 300 1430Vitamin D, IU 60 290Vitamin E, IU 2 9.5Vitamin K, mcg 8 38Thiamin (Vitamin B1), mcg 80 380Riboflavin (Vitamin B2), mcg 90 430Vitamin B6, mcg 60 290Vitamin B12, mcg 0.3 1.43Niacin, mcg 1000 4800Folic acid (Folacin), mcg 16 76Pantothenic acid, mcg 500 2400Biotin, mcg 3 14.3Vitamin C (Ascorbic acid), mg 12 57Choline, mg 24 114Inositol, mg 6 29

MineralsCalcium, mg 195 930Phosphorus, mg 130 620Magnesium, mg 11 52Iron, mg 2 9.5Zinc, mg 1.2 5.7Manganese, mcg 50 240Copper, mcg 75 360Iodine, mcg 15 71Selenium, mcg 2.8 13.3Sodium, mg 36 171Potassium, mg 120 570Chloride, mg 80 380


98

NUTRIENT FACTSNutrient Density 20 Calories/fl ozProtein (% calories) 13Fat (% calories) 40Carbohydrate (% calories) 47Potential Renal Solute Load (mOsm/100 Calories)12 30Potential Renal Solute Load (mOsm/100 mL)12 20Osmolality (mOsm/kg water) 230Osmolarity (mOsm/L) 200Gluten-Free YesLactose-Free YesGalactose-Free Yes

PRODUCT FORM Enfagrow™ Soy NEXT STEP® is available in powder. For information aboutordering, please see page 214.

COMPOSITION Ingredients: Powder: Corn syrup solids (58%), vegetable oil (palm olein, soy,coconut, and high oleic sunflower oils) (20%), soy protein isolate (17%), calciumphosphate (3%), and less than 1%: Mortierella alpina oil,† Crypthecodinium cohniioil,‡ vitamin A palmitate, vitamin D3, vitamin E acetate, vitamin K1, thiaminhydrochloride, riboflavin, vitamin B6 hydrochloride, vitamin B12, niacinamide, folicacid, calcium pantothenate, biotin, ascorbic acid, choline chloride, inositol,potassium phosphate, magnesium chloride, ferrous sulfate, zinc sulfate, cupricsulfate, potassium iodide, sodium selenite, sodium chloride, potassium chloride,potassium citrate, potassium hydroxide, L–methionine, taurine, L–carnitine.†A source of arachidonic acid (ARA).‡A source of docosahexaenoic acid (DHA).



Powder





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Powder (use scoop insideTo Make§ Water can to measure powder) Weight6 fl oz bottle 6 fl oz 3 unpacked level scoop 27.9 g8 fl oz bottle 8 fl oz 4 unpacked level scoops 37.2 g1 quart 29 fl oz 11⁄3 unpacked level 135 g




Powder Storage

Store cans at room temperature. After opening the can, keep it tightly covered,store in dry area, and use the contents within 1 month. Do not freeze powderand avoid excessive heat. Use by date on the bottom of the can.

CAUTION




REFERENCES1. Bhatia J, Greer F, and the American Academy of Pediatrics, Committee on Nutrition.

Use of soy protein-based formulas in infant feeding. Pediatrics. 2008;121:1062-1068.2. American Academy of Pediatrics, Committee on Nutrition. Iron fortification of infant

formulas. Pediatrics. 1999;104:119-123. Reaffirmed 11/02.3. Birch EE, Hoffman DR, Uauy RD, et al. Visual acuity and the essentiality of








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11. U.S. Department of Agriculture, Agricultural Research Service. 2006. USDA NationalNutrient Database for Standard Reference, Release 19. [database online]. Availableat: http://www.nal.usda.gov/fnic/foodcomp/search. Accessed September 29, 2006.



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Enfagrow™ Gentlease®

NEXT STEP®

For Fussiness and Gas

Milk-based formula with partially broken downproteins for ages 10-36 months

INDICATIONEnfagrow Gentlease NEXT STEP can be helpful in situations where Enfamil®

Gentlease® was used in infancy and sensitivity appears to continue into thetoddler ages 10-36 months. Enfagrow Gentlease NEXT STEP with Triple HealthGuard™ provides a strong nutritional foundation for your toddler during a criticaltime of development. It contains an easy-to-digest milk protein blend with awhey to casein ratio of 60:40 that has been partially broken down. It also hasabout 1⁄2 the lactose of a full-lactose, routine, milk-based infant and toddlerformula. The formula is nutritionally balanced and includes docosahexaenoicacid (DHA) and arachidonic acid (ARA), nutrients shown to promote brain andeye development.

According to the American Academy of Pediatrics (AAP), iron-fortified infantformula should be used if breastfeeding is not chosen, is discontinued during thefirst year, or if a supplement to breast milk is desired.1 Cow’s milk is notrecommended before the first birthday.

PRODUCT FEATURES• Similar to Enfamil Gentlease but for older babies experiencing fussiness

and gas2,*

• A special blend of easy-to-digest proteins that have been partially broken down

• A blend of carbohydrates with a reduced level of lactose† designed for toddlerswith fussiness or gas


• Includes choline, which is also important for brain development*vs the same babies at the beginning of the study.†Approximately 1⁄2 the lactose of a full-lactose, routine, milk-based infant and toddlerformula.

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NUTRIENTS‡


Protein, g 2.6 12.9Fat, g 5.3 26




MineralsCalcium, mg 195 970Phosphorus, mg 130 650Magnesium, mg 8 40Iron, mg 2 9.9Zinc, mg 1 5Manganese, mcg 15 75Copper, mcg 75 370Iodine, mcg 15 75Selenium, mcg 2.8 13.9Sodium, mg 40 200Potassium, mg 130 650Chloride, mg 80 400Molybdenum, mcg NA NAChromium, mcg NA NA

‡Product nutrient values and ingredients are subject to change. Please see product labelfor current information.

NA=None Added

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NUTRIENT FACTSNutrient Density 20 Calories/fl ozProtein (% calories) 10Fat (% calories) 48Carbohydrate (% calories) 42Potential Renal Solute Load (mOsm/100 Calories)11 26Potential Renal Solute Load (mOsm/100 mL)11 17.8Osmolality (mOsm/kg water) 230Osmolarity (mOsm/L) 210Gluten-Free YesLactose-Free NoGalactose-Free§ No

§Not recommended for patients with galactosemia.

PRODUCT FORMEnfagrow™ Gentlease® NEXT STEP® is available in powder. For orderinginformation, please refer to page 214.

COMPOSITIONIngredients: Powder: Corn syrup solids, partially hydrolyzed nonfat milk andwhey protein concentrate solids (soy), vegetable oil (palm olein, coconut, soy,and high oleic sunflower oils), calcium phosphate and less than 2%: Mortierellaalpina oil,|| Crypthecodinium cohnii oil,¶ vitamin A palmitate, vitamin D3, vitamin Eacetate, vitamin K1, thiamine hydrochloride, riboflavin, vitamin B6 hydrochloride,vitamin B12, niacinamide, folic acid, calcium pantothenate, biotin, ascorbic acid,choline chloride, inositol, calcium chloride, magnesium phosphate, ferroussulfate, zinc sulfate, manganese sulfate, cupric sulfate, potassium chloride,potassium iodide, sodium selenite, taurine, L-carnitine.||A source of arachidonic acid (ARA).¶A source of docosahexaenoic acid (DHA).

POTENTIAL ALLERGENSEnfagrow Gentlease NEXT STEP contains milk and soy.



Powder





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To Make# Water Powder Weight6 fl oz 6 fl oz 3 unpacked level scoops 27 g8 fl oz 8 fl oz 4 unpacked level scoops 36 g1 quart 28.5 fl oz 1 level household measuring cup 129 g

plus 3 level tablespoonsof unpacked powder

#Each scoop adds about 0.2 fl oz to the amount of prepared formula.


Powder Storage


CAUTION




REFERENCES1. American Academy of Pediatrics, Committee on Nutrition. Iron fortification of infant formulas.

Pediatrics. 1999;104:119-123. Reaffirmed 11/02.2. Berseth C, Mitmesser S, Ziegler E, Marunycz J, Vanderhoof J. Tolerance of a standard

intact protein formula versus a partially hydrolyzed formula in healthy, term infants. Nutr J.2009;8:27.

3. Birch EE, Hoffman DR, Uauy RD, et al. Visual acuity and the essentiality of docosahexaenoicacid and arachidonic acid in the diet of term infants. Pediatr Res. 1998;44:201-209.

4. Birch EE, Garfield S, Hoffman DR, et al. A randomized controlled trial of early dietary supplyof long-chain polyunsaturated fatty acids and mental development in term infants. Dev MedChild Neurol. 2000;42:174-181.

5. Birch EE, Hoffman DR, Castañeda YS, et al. A randomized controlled trial of long-chainpolyunsaturated fatty acid supplementation of formula in term infants after weaning at 6 wkof age. Am J Clin Nutr. 2002;75:570-580.

6. Hoffman DR, Birch EE, Castañeda YS, et al. Maturation of visual and mental function in 18-month old infants receiving dietary long-chain polyunsaturated fatty acids (LCPUFAs)[abstract]. FASEB J. 2003;17:A727-A728. Abstract 445.1.

7. Hoffman DR, Birch EE, Castañeda YS, et al. Visual function in breast-fed term infants weanedto formula with or without long-chain polyunsaturates at 4 to 6 months: a randomized clinicaltrial. J Pediatr. 2003;142:669-677.

8. Hoffman DR, Birch EE, Birch DG, et al. Impact of early dietary intake and blood lipidcomposition of long-chain polyunsaturated fatty acids on later visual development. J PediatrGastroenterol Nutr. 2000;31:540-553.

9. Birch EE, Castañeda YS, Wheaton DH, et al. Visual maturation of term infants fed long-chainpolyunsaturated fatty acid-supplemented or control formula for 12 mo. Am J Clin Nutr.2005;81:871-879.

10. Morale SE, Hoffman DR, Castañeda, YS, et al. Duration of long-chain polyunsaturated fattyacids availability in the diet and visual acuity. Early Hum Dev. 2005;81:197-203.

11. Fomon SJ, Ziegler EE. Renal solute load and potential renal solute load in infancy. J Pediatr.1999;134:11-14.


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Enfagrow™

PREMIUM™

Toddler VanillaMilk-based Formula for Toddlers 12–36 Months

INDICATIONEnfagrow PREMIUM Toddler Vanilla is a great-tasting, milk-based formula fortoddlers 12–36 months who are transitioning from infant formula or breast milk.Enfagrow PREMIUM Toddler Vanilla with Triple Health Guard™ provides a strongnutritional foundation for a toddler during a critical time of development. It has as much calcium and vitamin D as whole milk for toddlers.

PRODUCT FEATURES• DHA and iron to support brain development for toddlers

• 25 nutrients for healthy growth

• Antioxidants to help support the immune system

• Calcium and vitamin D to support bone development

• Prebiotics for digestive health


• Flavored and sweetened to increase acceptance

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(serving) Powder (470 Cal)Protein, g 7 18.6Fat, g 8 22

Linoleic acid, mg 300 830Linolenic acid, mg 30 83DHA, mg 17 47ARA, mg NA NA

Carbohydrate, g 18 49Water, g 181 3Vitamins/Other Nutrients

Vitamin A, IU 820 2300Vitamin D, IU 100 280Vitamin E, IU 2.7 7.5Vitamin K, mcg NA NAThiamin (Vitamin B1), mcg 300 830Riboflavin (Vitamin B2), mcg 360 1000Vitamin B6, mcg 360 1000Vitamin B12, mcg 0.55 1.53Niacin, mcg 5800 16100Folic acid (Folacin), mcg 57 158Pantothenic acid, mcg 1130 3100Biotin, mcg 30 83Vitamin C (Ascorbic acid), mg 10 28Choline, mg NA NAInositol, mg NA NACarnitine, mg NA NATaurine, mg NA NA

MineralsCalcium, mg 270 750Phosphorus, mg 210 580Magnesium, mg 38 106Iron, mg 2.5 6.9Zinc, mg 2.7 7.5Manganese, mcg 860 2400Copper, mcg 300 830Iodine, mcg 50 139Selenium, mcg NA NASodium, mg 80 220Potassium, mg 300 830Chloride, mg 180 500Molybdenum, mcg NA NAChromium, mcg NA NA


NA=None Added

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NUTRIENT FACTSNutrient Density Calories/fl ozProtein (% calories) 16Fat (% calories) 43Carbohydrate (% calories) 41Potential Renal Solute Load (mOsm/100 Calories)1 36Potential Renal Solute Load (mOsm/100 mL)1 29Osmolality (mOsm/kg water) Not availableOsmolarity (mOsm/L) Not availableGluten-Free YesLactose-Free NoGalactose-Free† No

†Not recommended for patients with galactosemia.

PRODUCT FORMEnfagrow™ PREMIUM™ Toddler Vanilla is available in powder, 24 oz (680 g) can.For ordering information, please refer to page 214.

COMPOSITIONIngredients: Powder: Whole milk,‡ nonfat milk, sugar, galactooligosaccharides,§

high oleic sunflower oil, maltodextrin, and less than 2%: tuna fish oil,|| magnesiumphosphate, calcium carbonate, ferrous sulfate, zinc sulfate, manganese sulfate,¶

cupric sulfate, natural and artificial flavor, sodium ascorbate, niacinamide,ascorbic acid, calcium pantothenate, vitamin B6 hydrochloride, thiaminhydrochloride, vitamin D3, riboflavin, folic acid, biotin, vitamin E acetate, vitamin A palmitate.‡A source of linoleic acid and linolenic acid§A type of prebiotic.||A source of docosahexaenoic acid (DHA)¶A source of manganese

POTENTIAL ALLERGENSEnfagrow PREMIUM Toddler Vanilla contains milk.

PREPARATION OF FEEDINGSPowder


To Make Water Powder Weight7 fl oz 6 fl oz 4 unpacked level scoops (1⁄3 cup) 36 g1 quart 28 fl oz 11⁄2 level household measuring cups 162 g

of unpacked powder

Powder Storage


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CAUTION



REFERENCE1. Fomon SJ, Ziegler EE. Renal solute load and potential renal solute load in infancy.

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Enfagrow™

PREMIUM™

Toddler ChocolateMilk-based Formula for Toddlers 12–36 Months

INDICATIONEnfagrow PREMIUM Toddler Chocolate is a great-tasting, milk-based formula for toddlers 12–36 months who are transitioning from infant formula or breastmilk. Enfagrow PREMIUM Toddler Chocolate with Triple Health Guard™provides a strong nutritional foundation for a toddler during a critical time ofdevelopment. It has as much calcium and vitamin D as whole milk for toddlers.

PRODUCT FEATURES• DHA and iron to support brain development for toddlers

• 25 nutrients for healthy growth

• Antioxidants to help support the immune system

• Calcium and vitamin D to support bone development

• Prebiotics for digestive health


• Flavored and sweetened to increase acceptance

110


(serving) Powder (420 Cal)Protein, g 6 15.8Fat, g 4.5 13.1

Linoleic acid, mg 140 390Linolenic acid, mg 28 78DHA, mg 17 47ARA, mg NA NA

Carbohydrate, g 22 61Water, g 181 2.4Vitamins/Other Nutrients

Vitamin A, IU 820 2300Vitamin D, IU 100 280Vitamin E, IU 2.7 7.5Vitamin K, mcg NA NAThiamin (Vitamin B1), mcg 300 830Riboflavin (Vitamin B2), mcg 360 1000Vitamin B6, mcg 360 1000Vitamin B12, mcg 0.55 1.53Niacin, mcg 5800 16100Folic acid (Folacin), mcg 57 158Pantothenic acid, mcg 1130 3100Biotin, mcg 30 83Vitamin C (Ascorbic acid), mg 10 28Choline, mg NA NAInositol, mg NA NACarnitine, mg NA NATaurine, mg NA NA

MineralsCalcium, mg 270 750Phosphorus, mg 210 580Magnesium, mg 38 106Iron, mg 2.5 6.9Zinc, mg 2.7 7.5Manganese, mcg 860 2400Copper, mcg 300 830Iodine, mcg 50 139Selenium, mcg NA NASodium, mg 85 240Potassium, mg 270 750Chloride, mg 180 500Molybdenum, mcg NA NAChromium, mcg NA NA


NA=None Added

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NUTRIENT FACTSNutrient Density Calories/fl ozProtein (% calories) 15Fat (% calories) 28Carbohydrate (% calories) 57Potential Renal Solute Load (mOsm/100 Calories)1 37Potential Renal Solute Load (mOsm/100 mL)1 26Osmolality (mOsm/kg water) Not availableOsmolarity (mOsm/L) Not availableGluten-Free YesLactose-Free NoGalactose-Free† No

†Not recommended for patients with galactosemia.

PRODUCT FORMEnfagrow™ PREMIUM™ Toddler Chocolate is available in powder, 24 oz (680 g) can. For ordering information, please refer to page 214.

COMPOSITIONIngredients: Powder: Whole milk,‡ nonfat milk, sugar, cocoa processed withalkali, galactooligosaccharides,§ high oleic sunflower oil, maltodextrin, and less than 2%: tuna fish oil,|| magnesium phosphate, ferrous sulfate, calciumphosphate, zinc sulfate, manganese sulfate,¶ cupric sulfate, sodium ascorbate,niacinamide, ascorbic acid, soy lecithin, calcium pantothenate, vitamin B6

hydrochloride, thiamin hydrochloride, vitamin D3, riboflavin, folic acid, biotin,vitamin E acetate, vitamin A palmitate, sodium chloride, natural and artificialflavor.‡A source of linoleic acid and linolenic acid.§A type of prebiotic.||A source of docosahexaenoic acid (DHA).¶A source of manganese.

POTENTIAL ALLERGENSEnfagrow PREMIUM Toddler Chocolate contains milk and soy.

PREPARATION OF FEEDINGSPowder


To Make Water Powder Weight7 fl oz 6 fl oz 4 unpacked level scoops (1⁄4 cup) 36 g1 quart 28 fl oz 11⁄4 level household measuring cup 166 g

of unpacked powder

Powder Storage


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CAUTION




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Products for Special Medical Needs

Portagen®

Milk-based Powder with Medium-chain Triglycerides (MCT) for Children and Adults

INDICATIONPortagen is a nutritional powder for children and adults with defects in theintraluminal hydrolysis of fat (decreased pancreatic lipase, decreased bile salts);defective mucosal fat absorption (decreased mucosal permeability, decreasedabsorptive surface); and/or defective lymphatic transport of fat (ie, intestinallymphatic obstruction).

Portagen is not recommended for use as an infant formula.

Long-Term Usage

Portagen powder is not nutritionally complete. If used long term,supplementation of essential fatty acids and ultra-trace minerals should beconsidered.

PRODUCT FEATURES • 87% of fat from medium-chain triglycerides

• Corn oil provides linoleic acid

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NUTRIENTS*Prepared Beverage

(Normal Dilution) Per 100 per quart % RDIgrams Powder (30 Calories/fl oz) (per quart)

Calories 470 960Protein, g 16.5 34 68†

Fat, g 22 46 ‡Linoleic acid, mg 1620 3300 ‡Linolenic acid, mg ND ND ‡Cholesterol, mg 4 8.1 ‡

Carbohydrate, g 54 110 ‡Dietary Fiber, g 0 0 ‡Water, g 3 820 ‡Vitamins/Other Nutrients

Vitamin A, IU 3700 7500 150Vitamin D, IU 370 750 188Vitamin E, IU 14.7 30 100Vitamin K, mcg 74 150 188Thiamin (Vitamin B1), mg 0.74 1.5 100Riboflavin (Vitamin B2), mg 0.88 1.8 106Vitamin B6, mg 0.98 2 100Vitamin B12, mcg 2.9 6 100Niacin, mg 9.8 20 100Folic acid (Folacin), mcg 74 150 38Pantothenic acid, mg 4.9 10 100Biotin, mcg 37 75 25Vitamin C (Ascorbic acid), mg 38 78 130Choline, mg 61 125 ‡Inositol, mg 22 45 ‡Carnitine, mg 8.8 18 ‡Taurine, mg 28 57 ‡

MineralsCalcium, mg 440 900 90Phosphorus, mg 330 680 68Magnesium, mg 98 200 50Iron, mg 8.8 18 100Zinc, mg 4.4 9 60Manganese, mg 0.59 1.2 60Copper, mg 0.74 1.5 75Iodine, mcg 34 70 47Selenium, mcg NA NA NASodium, mg 260 530 ‡Potassium, mg 590 1200 ‡Chloride, mg 410 830 ‡Molybdenum, mcg NA NA ‡Chromium, mcg NA NA ‡


†Percent Daily Reference Value (DRV).‡Reference Daily Intake (RDI) not established.ND=Not Declared NA=None Added

116

NUTRIENT FACTSNutrient Density 30 Calories/fl ozProtein (% calories) 14Fat (% calories) 40Carbohydrate (% calories) 46Potential Renal Solute Load (mOsm/L)1 300Osmolality (mOsm/kg water) 350Osmolarity (mOsm/L formula) 300Total Calorie:Nitrogen Ratio 180:1Nonprotein Calorie:Nitrogen Ratio 155:1Water (g/L) 870Gluten-Free YesLactose-Free Yes§

Low Residue Yes

§Not suitable for persons with galactosemia.

PRODUCT FORMPortagen® is available in powder. For ordering information, please refer to page 214.

COMPOSITIONIngredients: Powder: Corn syrup solids, medium-chain triglycerides (MCT) oil,sodium caseinate, sugar, corn oil, and less than 2%: vitamin A palmitate, vitaminD3, vitamin E acetate, vitamin K1, thiamin hydrochloride, riboflavin, vitamin B6

hydrochloride, vitamin B12, niacinamide, folic acid, calcium pantothenate, biotin,ascorbic acid, choline chloride, inositol, calcium citrate, calcium phosphate,magnesium phosphate, ferrous sulfate, zinc sulfate, manganese sulfate, cupricsulfate, sodium iodide, potassium citrate, potassium chloride, taurine, L-carnitine,soy lecithin.

POTENTIAL ALLERGENSPortagen contains milk protein.

PREPARATION OF FEEDINGSImproper hygiene, preparation, dilution, use, or storage may result in severeharm. This product is not recommended for use as an infant formula.Nutritional powders are not sterile and should not be fed to prematureinfants or those persons who might have immune problems unless directedand supervised by a medical professional.

Powder





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To Make|| Water Powder Weight4.5 fl oz 4 fl oz 3 packed level scoops 28.2 g1 qt 27.5 fl oz 12⁄3 packed level 203 g



Failure to follow these instructions could result in severe harm. Onceprepared, product can spoil quickly. Either consume immediately or cover andstore in refrigerator at 35–40°F (2–4°C) for no longer than 24 hours. Shake wellbefore each use. Do not use prepared product if it is unrefrigerated for morethan a total of 2 hours. Do not freeze prepared product. After feeding begins, donot refrigerate the container. You must use within 1 hour or discard.

Powder Storage


CAUTION

Portagen® should be used only under the supervision of a physician. It is notnutritionally complete.

Persons should drink Portagen beverage slowly and start with one or two smallservings per day until they become accustomed to the product, since abdominaldiscomfort and/or diarrhea may occur.

WARNING: Not for parenteral (I.V.) use.

Powdered products are not commercially sterile. Nutritional powders should notbe used for immunocompromised patients unless clinically required and thenunder strict medical supervision of preparation and use.

REFERENCES1. Fomon SJ, Ziegler EE. Renal solute load and potential renal solute load in infancy.

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3232A™

INDICATION3232 A is a protein hydrolysate formula base that is to be used with addedcarbohydrate. It contains tapioca starch. It is for use in the dietary managementof infants and children with disaccharidase deficiencies or other disorders ofcarbohydrate metabolism under the direct and continuing supervision of adoctor.

Long-Term Usage

3232 A is not nutritionally complete. If used long term, additional essential fattyacids should be considered.

To be used only under the supervision of a doctor.

PRODUCT FEATURES • Allows adjustment of added carbohydrate according to patient’s tolerance

• Hypoallergenic, protein hydrolysate

• 85% of the fat from medium-chain triglycerides (MCT) oil

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NUTRIENTS*Per 100 Calories† Per 100 grams

(5 fl oz) Powder (500 Cal)Protein, g 2.8 22Fat, g‡ 4.2 33

Linoleic acid, mg 340 2700Carbohydrate, g‡ 13.4 33Water, g 127 3Vitamins/Other Nutrients

Vitamin A, IU 380 3000Vitamin D, IU 75 590Vitamin E, IU 3.8 30Vitamin K, mcg 18.8 148Thiamin (Vitamin B1), mcg 78 610Riboflavin (Vitamin B2), mcg 94 740Vitamin B6, mcg 63 490Vitamin B12, mcg 0.31 2.5Niacin, mcg 1250 9800Folic acid (Folacin), mcg 15.6 123Pantothenic acid, mcg 470 3700Biotin, mcg 7.8 61Vitamin C (Ascorbic acid), mg 11.7 92Choline, mg 13.3 105Inositol, mg 4.7 37Carnitine, mg 1.88 14.8Taurine, mg 5.9 47

MineralsCalcium, mg 94 740Phosphorus, mg 63 490Magnesium, mg 10.9 86Iron, mg 1.88 14.8Zinc, mg 0.63 4.9Manganese, mcg 31 250Copper, mcg 94 740Iodine, mcg 7 55Selenium, mcg NA NASodium, mg 43 340Potassium, mg 109 860Chloride, mg 86 680Molybdenum, mcg NA NAChromium, mcg NA NA


†Using 81 grams of 3232 A™ and 59 grams of carbohydrate per quart of preparedproduct.

‡Care must be taken to provide essential fatty acids and sufficient carbohydrates.NA=None Added

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NUTRIENT FACTSNutrient Density Prepared with 59 grams Prepared with no

added carbohydrate at carbohydrate at20 Calories/fl oz 12.7 Calories/fl oz

Protein (% calories) 11 18Fat (% calories) 35 55Carbohydrate (% calories) 54 27Potential Renal Solute Load

(mOsm/100 Calories)1 25 40Potential Renal Solute

(mOsm/100 mL)1 16.9 16.9Gluten-Free Yes YesLactose-Free§ Yes YesGalactose-Free§ Yes Yes

§Prepared product is lactose- and galactose-free.

Osmolality0 added 30 g added 59 g added

Carbohydrate carbohydrate carbohydrate carbohydrateCorn Syrup Solids 250 mOsm/kg 290 mOsm/kg 360 mOsm/kg

water water waterSucrose 250 mOsm/kg 350 mOsm/kg 430 mOsm/kg

water water waterGlucose 250 mOsm/kg 430 mOsm/kg 640 mOsm/kg

water water water

Osmolarity0 added 30 g added 59 g added

Carbohydrate carbohydrate carbohydrate carbohydrateCorn Syrup Solids 230 mOsm/L 270 mOsm/L 330 mOsm/L

Sucrose 230 mOsm/L 330 mOsm/L 400 mOsm/LGlucose 230 mOsm/L 400 mOsm/L 600 mOsm/L

PRODUCT FORM3232 A™ is available in powder. For ordering information, please refer to page214.

COMPOSITIONIngredients: Powder: Modified tapioca starch (35%), medium-chain triglycerides(MCT) oil (28%), casein hydrolysate (from milk)|| (27%), corn oil (5%), and less than2%: vitamin A palmitate, vitamin D3, vitamin E acetate, vitamin K1, thiaminhydrochloride, riboflavin, vitamin B6 hydrochloride, vitamin B12, niacinamide, folicacid, calcium pantothenate, biotin, sodium ascorbate, choline chloride, inositol,calcium citrate, calcium hydroxide, calcium phosphate, magnesium oxide, ferroussulfate, zinc sulfate, manganese sulfate, cupric sulfate, sodium chloride, sodiumiodide, potassium citrate, potassium phosphate, soy lecithin, L-cystine,L-tyrosine, L-tryptophan, taurine, L-carnitine.||Modified to be better tolerated in milk-allergic babies.

POTENTIAL ALLERGENSThe ingredients in 3232 A are hypoallergenic. Rarely, however, allergic reaction toextensively hydrolyzed casein formulas has been reported.

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PREPARATION OF FEEDINGSThe child’s health depends on carefully following these instructions. Useonly as directed by a medical professional. Improper hygiene, preparation,dilution, use, or storage may result in severe harm. Powdered formulas arenot sterile and should not be fed to premature infants or infants whomight have immune problems unless directed and supervised by a doctor.


Parents should consult their child’s doctor for instructions for the correctamounts of water and powder. Each scoop (unpacked and leveled) deliversapproximately 4.5 g of powder. Pour desired amount of water into the bottle.Add powder, cap, and shake vigorously.

Powder


2. Add 81 g of powder (packed, level 1/2 cup) and 59 g of the desiredcarbohydrate to 4 fl oz (120 mL) of water in a clean bottle or container.

3. Mix well with fork or mixer until a smooth paste is formed.

4. Add additional water to make one quart. Initial feedings of 3232 A™ may needto contain less than the full 59 g of carbohydrate recommended or the formulamay need to be diluted to 10 Calories/fl oz or less and gradually increased to20 Calories/fl oz.

If incremental addition of carbohydrate is desired, consult Table 1.

Table 1

Incremental Addition of Carbohydrate (CHO) to 3232 A

Added CHO per 100 mL¶# (g) 0 0.1 1.2 2.1 3.2 4.1 5.2 6.1 6.2Total CHO per 100 mL¶** (g) 2.8 3 4 5 6 7 8 9 9.1CHO to add per Quart (g) 0 1 11 20 30 39 49 58 59Total CHO per Quart

of Prepared Formula†† (g) 27 28 38 47 57 66 76 85 86Calories/fl oz

of Prepared Formula** 12.7 12.8 14 15.2 16.4 17.5 18.8 19.9 20

¶g of CHO per 100 mL = approximate % (weight volume) CHO concentration. #Values are for added CHO (does not include modified tapioca starch present in thediet powder).

**Includes added CHO and modified tapioca starch (stabilizer) present in the dietpowder.

††Prepared formula includes 81 g diet powder, the added carbohydrate, and wateradded to make one quart.

Failure to follow these instructions could result in severe harm. Onceprepared, formula can spoil quickly. Either feed immediately or cover and storein refrigerator at 35–40°F (2–4°C) for no longer than 24 hours. Do not useprepared formula if it is unrefrigerated for more than a total of 2 hours. Do notfreeze prepared formula. After feeding begins, do not refrigerate the bottle orcontainer. You must use within 1 hour or discard.

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Powder Storage


CAUTION


3232 A™ is nutritionally incomplete. Care must be taken to provide enoughcarbohydrate to support growth. Use other foods with 3232 A as required. If usedlong term, supplementation of essential fatty acids should be considered. To beused only under the supervision of a doctor.




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Enfaport®

Complete Nutrition for Infants with Chylothorax or LCHAD Deficiency

INDICATIONEnfaport is designed to meet the unique nutritional needs of infants withChylothorax or LCHAD deficiency. Enfaport balances high levels of MCT oil for easier absorption, along with DHA and ARA, important fatty acids for infant development.

PRODUCT FEATURES • High level of MCT oil, for easier fat absorption

• High protein level to meet special needs

• Includes all essential fatty acids

• Includes our blend of DHA and ARA, nutrients also found in breast milk, thatpromotes brain and eye development.1-8

• Commercially sterile ready-to-use liquid

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NUTRIENTS*(Normal Dilution) Per 100 CalProtein, g 3.5Fat, g 5.4

Linoleic acid, mg 350Linolenic acid, mg 50DHA, mg 17ARA, mg 34

Carbohydrate, g 10.2Water, g 83Vitamins/Other Nutrients

Vitamin A, IU 350Vitamin D, IU 50Vitamin E, IU 4Vitamin K, mcg 12Thiamin (Vitamin B1), mcg 80Riboflavin (Vitamin B2), mcg 90Vitamin B6, mcg 68Vitamin B12, mcg 0.3Niacin, mcg 1000Folic acid (Folacin), mcg 16Pantothenic acid, mcg 500Biotin, mcg 3Vitamin C (Ascorbic acid), mg 12Choline, mg 24Inositol, mg 17Carnitine, mg 2Taurine, mg 6

MineralsCalcium, mg 94Phosphorus, mg 52Magnesium, mg 11Iron, mg 1.8Zinc, mg 1Manganese, mcg 25Copper, mcg 75Iodine, mcg 15Selenium, mcg 2.8Sodium, mg 30Potassium, mg 115Chloride, mg 87Molybdenum, mcg NAChromium, mcg NA


NA=None Added

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NUTRIENT FACTSNutrient Density 30 Cal/fl ozProtein (% calories) 14Fat (% calories) 45Carbohydrate (% calories) 41Potential Renal Solute Load (mOsm/100 Calories)9 28Potential Renal Solute Load (mOsm/100 mL)9 29Osmolality (mOsm/kg water) 280Osmolarity (mOsm/L) 240Gluten-Free YesLactose-Free YesGalactose-Free No†

†Trace amounts of galactose may come in with the milk protein.

PRODUCT FORMEnfaport® is available in ready-to-use liquid. For ordering information, pleaserefer to page 214.

COMPOSITIONIngredients: Ready to Use: Water, corn syrup solids, medium-chain triglycerides(MCT oil), calcium caseinate (from milk), sodium caseinate (from milk), soy oil, and less than 0.5%: Mortierella alpina oil,‡ Crypthecodinium cohnii oil,§ soylecithin, carrageenan, vitamin A palmitate, vitamin D3, vitamin E acetate, vitamin K1, thiamin hydrochloride, riboflavin, vitamin B6 hydrochloride, vitamin B12, niacinamide, folic acid, calcium pantothenate, biotin, ascorbic acid,choline chloride, inositol, calcium carbonate, calcium chloride, magnesiumphosphate, potassium phosphate, ferrous sulfate, zinc sulfate, manganesesulfate, cupric sulfate, potassium iodide, magnesium chloride, potassiumchloride, sodium chloride, potassium citrate, potassium hydroxide, sodiumselenite, taurine, L-carnitine.‡A source of arachidonic acid (ARA).§A source of docosahexaenoic acid (DHA).

POTENTIAL ALLERGENSEnfaport contains milk.


Ready To Use




The child’s doctor may recommend other mixing instructions to achieve variouscaloric densities.

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When caloric densities lower than 30 Cal/fl oz are needed, use the following:

Cal/fl oz Water Enfaport To Make20 4 fl oz (118 mL) 8 fl oz 12 fl oz (355 mL) 22 2.9 fl oz (86 mL) 8 fl oz 10.9 fl oz (322 mL) 24 2 fl oz (59 mL) 8 fl oz 10 fl oz (296 mL) 26 1.2 fl oz (35 mL) 8 fl oz 9.2 fl oz (272 mL) 27 0.9 fl oz (27 mL) 8 fl oz 8.9 fl oz (263 mL) 28 0.6 fl oz (18 mL) 8 fl oz 8.6 fl oz (254 mL)




CAUTION








5. Hoffman DR, Birch EE, Castañeda YS, et al. Maturation of visual and mental function in18-month-old infants receiving dietary long-chain polyunsaturated fatty acids(LCPUFAs) [abstract]. FASEB J. 2003;17:A727-A728. Abstract 445.1.






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MetabolicFormulas

BCAD™ 1

INDICATIONBCAD 1 is an isoleucine-, leucine-, and valine-free, iron-fortified dietary powderfor the dietary management of infants and toddlers with maple syrup urinedisease (MSUD). The product provides the essential amino acids (exceptisoleucine, leucine, and valine) as well as nonessential amino acids, carbohydrate,fat, essential fatty acids, vitamins, and minerals. BCAD refers to branched chainamino acid disorder. Use under direct and continuing supervision of a doctor.

PRODUCT FEATURES• Isoleucine-, leucine-, and valine-free

• Vitamin and mineral levels meet the U.S. Infant Formula Act requirements per100 Calories

• Increased levels of B vitamins, compared to routine infant formulas, for cofactorproduction

• Improved taste; sucrose (table sugar) has been added to neutralize the taste ofthe amino acids

• Vanilla scent

• Mixes easily and stays in suspension well

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NUTRIENTS*Per 100 grams

PowderCalories 500Protein equivalent, g† 16.2Fat, g 26


Carbohydrate, g 51Vitamins/Other Nutrients

Vitamin A, IU 1520Vitamin D, IU 380Vitamin E, IU 10Vitamin K, mcg 40Thiamin (Vitamin B1), mcg 1000Riboflavin (Vitamin B2), mcg 1000Vitamin B6, mcg 1000Vitamin B12, mcg 2Niacin, mcg 10000Folic acid (Folacin), mcg 100Pantothenic acid, mcg 3800Biotin, mcg 38Vitamin C (Ascorbic acid), mg 60Choline, mg 60Inositol, mg 86Taurine, mg 30Carnitine, mg 50

MineralsCalcium, mg 660Phosphorus, mg 440Magnesium, mg 66Iron, mg 9.6Zinc, mg 8.6Manganese, mcg 380Copper, mcg 860Iodine, mcg 76Selenium, mcg 14.1Sodium, mg 240Potassium, mg 600Chloride, mg 500Molybdenum, mcg NAChromium, mcg NA


†Protein is incomplete since it does not contain the essential amino acids isoleucine,leucine, and valine.

NA=None Added

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NUTRIENT FACTSProtein Equivalent (% calories)† 13Fat (% calories) 47Carbohydrate (% calories) 40Potential Renal Solute Load (mOsm/100 g powder)1 147Osmolality (mOsm/kg water) 340Osmolarity (mOsm/L) 310


PRODUCT FORMBCAD™ 1 is available in powder. For ordering information, please refer to page214.

COMPOSITIONIngredients: Vegetable oil (palm olein, soy, coconut, and high oleic sunfloweroils), corn syrup solids, amino acids (L-glutamine, L-lysine hydrochloride,potassium L-aspartate, L-proline, L-alanine, L-arginine, L-phenylalanine,L-tyrosine, L-serine, L-threonine, glycine, L-histidine, L-methionine, L-tryptophan,L-cystine), sugar, modified corn starch, calcium phosphate, maltodextrin, and lessthan 1%: vitamin A palmitate, vitamin D3, vitamin E acetate, vitamin K1, thiaminhydrochloride, riboflavin, vitamin B6 hydrochloride, vitamin B12, niacinamide, folic acid, calcium pantothenate, biotin, ascorbic acid, choline chloride, inositol,magnesium oxide, ferrous sulfate, zinc sulfate, manganese sulfate, cupric sulfate,potassium iodide, sodium selenite, sodium citrate, potassium citrate, potassiumchloride, L-carnitine, taurine, ethyl vanillin.

PREPARATION OF FEEDINGSThe baby’s health depends on carefully following these instructions. Properhygiene, preparation, dilution, use, and storage are important when preparingformula. Powdered formulas are not sterile and should not be fed to prematureinfants or those persons who might have immune problems unless directed andsupervised by a doctor.


Consult with parents about the correct amounts of water and powder. Eachscoop (unpacked and leveled) delivers approximately 4.5 g of powder. Pourdesired amount of water into the bottle. Add powder, cap, and shake vigorously.

Failure to follow these instructions could result in severe harm. Onceprepared, formula can spoil quickly. Either feed immediately or cover and storein refrigerator at 35–40°F (2–4°C) for no longer than 24 hours. Do not useprepared formula if it is unrefrigerated for more than a total of 2 hours. Do notfreeze prepared formula. After feeding begins, do not refrigerate feeding bottle.You must use within 1 hour or discard.

Powder Storage

Store cans at room temperature. After opening can, keep tightly covered, storein dry area, and use contents within 1 month. Do not freeze powder. Avoidexcessive heat. Use by date on can end.

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AD

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CAUTION


This product is nutritionally incomplete. Care must be taken to provide enoughisoleucine, leucine, and valine to support growth, using other foods with theseamino acids as required. The physician must carefully and constantly supervisethe use of BCAD™ 1 with other foods and adjust the diet based on frequentblood tests.

Use by date on can end.





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BCAD™ 2

INDICATIONBCAD 2 is a dietary powder that is free of the branched chain amino acids,isoleucine, leucine, and valine, for children and adults with maple syrup urinedisease (MSUD) or other inborn errors of branched chain amino acidmetabolism. The product provides the essential amino acids (except isoleucine,leucine, and valine) as well as nonessential amino acids, carbohydrate, fat,essential fatty acids, vitamins, and minerals. BCAD refers to branched chainamino acid disorder. Use under direct and continuing supervision of a doctor.

PRODUCT FEATURES• Isoleucine-, leucine-, and valine-free

• 24 g protein equivalents/100 g powder

• Higher level of protein equivalents than found in BCAD 1

• Lactose-free

• Vanilla scent

• Can be easily modified with preferred flavor enhancers


• Vitamin and mineral levels appropriate for children and adults

133

BC

AD

™2


PowderCalories 410Protein equivalent, g† 24Fat, g 8.5



Vitamin A, IU 1730Vitamin D, IU 350Vitamin E, IU 11.4Vitamin K, mcg 37Thiamin (Vitamin B1), mcg 1420Riboflavin (Vitamin B2), mcg 1140Vitamin B6, mcg 1140Vitamin B12, mcg 2.8Niacin, mcg 26000Folic acid (Folacin), mcg 410Pantothenic acid, mcg 5700Biotin, mcg 57Vitamin C (Ascorbic acid), mg 57Choline, mg 98Inositol, mg 57Taurine, mg 57Carnitine, mg 49

MineralsCalcium, mg 730Phosphorus, mg 730Magnesium, mg 163Iron, mg 12.2Zinc, mg 12.2Manganese, mcg 1300Copper, mcg 1220Iodine, mcg 57Selenium, mcg 28Sodium, mg 610Potassium, mg 1220Chloride, mg 1020Molybdenum, mcg 37Chromium, mcg 37



134

NUTRIENT FACTSProtein Equivalent (% calories)† 24Fat (% calories) 19Carbohydrate (% calories) 57Gluten-Free YesLactose-Free YesGalactose-Free Yes


PRODUCT FORMBCAD™ 2 is available in powder. For ordering information, please refer to page214.

COMPOSITIONIngredients: Amino acids (L-glutamine, potassium aspartate, L-lysinehydrochloride, L-tyrosine, L-proline, L-alanine, L-arginine, L-phenylalanine,L-threonine, L-serine, glycine, L-histidine, L-methionine, L-tryptophan, L-cystine),corn syrup solids, sugar, soy oil, modified corn starch, calcium phosphate,sodium citrate, magnesium phosphate and less than 1%: potassium chloride,sodium phosphate, potassium citrate, choline chloride, L-carnitine, ascorbic acid,inositol, taurine, niacinamide, vitamin E acetate, potassium iodide, vitamin Apalmitate, calcium pantothenate, biotin, vitamin K1, vitamin B12, thiaminhydrochloride, vitamin B6 hydrochloride, riboflavin, vitamin D3, folic acid, zincsulfate, chromic chloride, sodium selenite, cupric sulfate, manganese sulfate,sodium molybdate, ferrous sulfate, ethyl vanillin.

PREPARATION OF FEEDINGSConsult with patients about the correct amounts of water and powder. Thepatient’s health depends on carefully following these directions.

Pour desired amount of water into a suitable container. Add powder and mixwell. Consume immediately or cover and refrigerate prepared beverage. Usewithin 48 hours. Shake well before serving.

Throw away unrefrigerated beverage left in cup within 1 hour after consumptionbegins.

Store unopened cans at room temperature. After opening can, keep tightlycovered, store in a dry area, and use contents within 1 month. Do not freezepowder or prepared formula. Avoid excessive heat. Use by date on can end.

Scoop

A packed level scoop contains approximately 16.8 g of powder.

135

BC

AD

™2

CAUTION


BCAD™ 2 is nutritionally incomplete. Care must be taken to provide enoughisoleucine, leucine, and valine to support growth, using other foods with theseamino acids as required. The physician must carefully and constantly supervisethe use of BCAD 2 with other foods and adjust the diet based on frequent bloodtests.





136

GA™

INDICATIONGA is a lysine- and tryptophan-free, iron-fortified dietary powder for infants,children, and adults with glutaric acidemia type I. The product provides essentialamino acids (except lysine and tryptophan) as well as nonessential amino acids,carbohydrate, fat, essential fatty acids, vitamins, and minerals. GA refers toglutaric acidemia. Use under direct and continuing supervision of a doctor.

PRODUCT FEATURES• Lysine- and tryptophan-free




• Vanilla scent


137

GA

™








†Protein level is inadequate to meet normal infant growth and development needs usingGA alone.

NA=None Added

138

NUTRIENT FACTSProtein Equivalent (% calories)† 12Fat (% calories) 47Carbohydrate (% calories) 41Potential Renal Solute Load (mOsm/100 g powder)1 140Osmolality (mOsm/kg water) 400Osmolarity (mOsm/L) 360Gluten-Free YesLactose-Free YesGalactose-Free Yes

†Protein level is inadequate to meet normal infant growth and development needs usingGA alone.

PRODUCT FORMGA™ is available in powder. For ordering information, please refer to page 214.

COMPOSITIONIngredients: Vegetable oil (palm olein, soy, coconut, and high oleic sunfloweroils), corn syrup solids, amino acids (L-alanine, L-leucine, potassium L-aspartate,L-proline, L-valine, L-isoleucine, L-arginine, glycine, L-threonine, L-phenylalanine,L-tyrosine, L-serine, L-histidine, L-methionine, L-cystine), sugar, modified cornstarch, calcium phosphate, maltodextrin, and less than 1%: vitamin A palmitate,vitamin D3, vitamin E acetate, vitamin K1, thiamin hydrochloride, riboflavin,vitamin B6 hydrochloride, vitamin B12, niacinamide, folic acid, calciumpantothenate, biotin, ascorbic acid, choline chloride, inositol, magnesium oxide,ferrous sulfate, zinc sulfate, manganese sulfate, cupric sulfate, potassium iodide,sodium selenite, sodium citrate, potassium citrate, potassium chloride,L-carnitine, taurine, ethyl vanillin.

PREPARATION OF FEEDINGSThe consumer’s health depends on carefully following these instructions.Proper hygiene, preparation, dilution, use, and storage are important whenpreparing formula. Powdered formulas are not sterile and should not be fed topremature infants or those persons who might have immune problems unlessdirected and supervised by a medical professional.

If being fed to an infant, discuss with parents whether they need to use cooled,boiled water for mixing and whether they need to boil clean utensils, bottles,and nipples in water before use.

Consult with consumers about the correct amounts of water and powder.Each scoop (unpacked and leveled) delivers approximately 4.5 g of powder. Pourdesired amount of water into bottle/container. Add powder and mix vigorously.

Failure to follow these instructions could result in severe harm. Onceprepared, formula can spoil quickly. Either feed immediately or cover and storein refrigerator at 35–40°F (2–4°C) for no longer than 24 hours. Do not useprepared formula if it is unrefrigerated for more than a total of 2 hours. Do notfreeze prepared formula. After feeding begins, do not refrigerate feedingbottle/container. You must use within 1 hour or discard.

139

GA

™

Powder Storage

Store cans at room temperature. After opening can, keep tightly covered, storein a dry area, and use contents within 1 month. Do not freeze powder. Avoidexcessive heat. Use by date on can end.

CAUTION


This product is nutritionally incomplete. Care must be taken to provide enoughlysine and tryptophan to support growth, using other foods with these aminoacids as required. The physician must carefully and constantly supervise the useof GA™ with other foods and adjust the diet based on frequent blood tests.






J Pediatr. 1999;134:11-14.


140

HCY™ 1

INDICATIONHCY 1 is a methionine-free, iron-fortified dietary powder for infants and toddlerswith homocystinuria. The product provides the essential amino acids (exceptmethionine) as well as nonessential amino acids, carbohydrate, fat, essential fattyacids, vitamins, and minerals. HCY refers to homocysteine. Use under direct andcontinuing supervision of a doctor.

PRODUCT FEATURES• Methionine-free

• Added cystine




• Vanilla scent


141

HC

Y™

1








†Protein is incomplete since it does not contain the essential amino acid methionine.NA=None Added

142


†Protein is incomplete since it does not contain the essential amino acid methionine.

PRODUCT FORMHCY™ 1 is available in powder. For ordering information, please refer to page 214.

COMPOSITIONIngredients: Vegetable oil (palm olein, soy, coconut, and high oleic sunfloweroils), corn syrup solids, amino acids (L-glutamine, L-leucine, potassiumL-aspartate, L-lysine hydrochloride, L-proline, L-valine, L-isoleucine, L-alanine,L-arginine, L-threonine, L-phenylalanine, L-tyrosine, L-serine, L-cystine, glycine,L-histidine, L-tryptophan), modified corn starch, sugar, calcium phosphate,maltodextrin, and less than 1%: vitamin A palmitate, vitamin D3, vitamin Eacetate, vitamin K1, thiamin hydrochloride, riboflavin, vitamin B6 hydrochloride,vitamin B12, niacinamide, folic acid, calcium pantothenate, biotin, ascorbic acid,choline chloride, inositol, magnesium oxide, ferrous sulfate, zinc sulfate,manganese sulfate, cupric sulfate, potassium iodide, sodium selenite, sodiumcitrate, potassium citrate, potassium chloride, L-carnitine, taurine, ethyl vanillin.





143

HC

Y™

1

Powder Storage

Store cans at room temperature. After opening can, keep tightly covered, storein dry area, and use contents within 1 month. Do not freeze powder. Avoidexcessive heat.


CAUTION


This product is nutritionally incomplete. Care must be taken to provide enoughmethionine to support growth, using other foods with methionine as required.The physician must carefully and constantly supervise the use of HCY 1 withother foods and adjust the diet based on frequent blood tests.






J Pediatr. 1999;134:11-14.


144

HCY™ 2

INDICATIONHCY 2 is a methionine-free dietary powder for children and adults withhomocystinuria. The product provides the essential amino acids (exceptmethionine) as well as nonessential amino acids, carbohydrate, fat, essential fattyacids, vitamins, and minerals. HCY refers to homocysteine. Use under direct andcontinuing supervision of a doctor.

PRODUCT FEATURES• Methionine-free

• Cystine level is similar to the sum of cystine and methionine found in cow’s milk


• Lactose-free

• Vanilla scent




145

HC

Y™

2









146



PRODUCT FORMHCY™ 2 is available in powder. For ordering information, please refer to page 214.

COMPOSITIONIngredients: Sugar, corn syrup solids, amino acids (L-glutamine, L-leucine,L-lysine hydrochloride, potassium aspartate, L-proline, L-valine, L-isoleucine,L-alanine, L-arginine, L-threonine, L-phenylalanine, L-tyrosine, L-serine, L-cystine,glycine, L-histidine, L-tryptophan), soy oil, modified corn starch, calciumphosphate, sodium citrate, magnesium phosphate, and less than 1%: potassiumchloride, sodium phosphate, potassium citrate, choline chloride, L-carnitine,ascorbic acid, inositol, taurine, niacinamide, vitamin E acetate, potassium iodide,vitamin A palmitate, calcium pantothenate, biotin, vitamin K1, vitamin B12,thiamin hydrochloride, vitamin B6 hydrochloride, riboflavin, vitamin D3, folic acid,zinc sulfate, chromic chloride, sodium selenite, cupric sulfate, manganese sulfate,sodium molybdate, ferrous sulfate, ethyl vanillin.



Throw away prepared unrefrigerated beverage left in cup within 1 hour afterconsumption begins.


Scoop


CAUTION

HCY 2 is nutritionally incomplete. Care must be taken to provide enoughmethionine to support growth, using other foods with this amino acid asrequired. The physician must carefully and constantly supervise the use of HCY 2with other foods and adjust the diet based on frequent blood tests.





147

HC

Y™

2

LMD™

INDICATIONLMD is a leucine-free, iron-fortified dietary powder for infants, children, andadults with disorders of leucine metabolism, including isovaleric acidemia. Theproduct provides the essential amino acids (except leucine) as well asnonessential amino acids, carbohydrate, fat, essential fatty acids, vitamins, andminerals. LMD refers to leucine metabolism disorders. Use under direct andcontinuing supervision of a doctor.

PRODUCT FEATURES• Leucine-free




• Vanilla scent


148








†Protein is incomplete since it does not contain the essential amino acid leucine.NA=None Added

149

LMD

™


†Protein is incomplete since it does not contain the essential amino acid leucine.

PRODUCT FORMLMD™ is available in powder. For ordering information, please refer to page 214.

COMPOSITIONIngredients: Vegetable oil (palm olein, soy, coconut, and high oleic sunfloweroils), corn syrup solids, amino acids (L-alanine, L-lysine hydrochloride, potassiumL-aspartate, L-proline, L-arginine, glycine, L-threonine, L-phenylalanine,L-tyrosine, L-serine, L-valine, L-isoleucine, L-histidine, L-methionine, L-tryptophan,L-cystine), modified corn starch, sucrose, calcium phosphate, maltodextrin, andless than 1%: vitamin A palmitate, vitamin D3, vitamin E acetate, vitamin K1,thiamin hydrochloride, riboflavin, vitamin B6 hydrochloride, vitamin B12,niacinamide, folic acid, calcium pantothenate, biotin, ascorbic acid, cholinechloride, inositol, magnesium oxide, ferrous sulfate, zinc sulfate, manganesesulfate, cupric sulfate, potassium iodide, sodium selenite, sodium citrate,potassium citrate, potassium chloride, L-carnitine, taurine, ethyl vanillin.

PREPARATION OF FEEDINGSThe consumer’s health depends on carefully following these instructions.Proper hygiene, preparation, dilution, use, and storage are important whenpreparing formula. Powdered formulas are not sterile and should not be fed topremature infants or those persons who might have immune problems unlessdirected and supervised by a medical professional.

If being fed to an infant, discuss with parents whether they need to use cooled,boiled water for mixing and whether they need to boil clean utensils, bottles,and nipples in water before use.

Consult with consumers about the correct amounts of water and powder.Each scoop (unpacked and leveled) delivers approximately 4.5 g of powder. Pourdesired amount of water into bottle/container. Add powder and mix vigorously.

Failure to follow these instructions could result in severe harm. Onceprepared, formula can spoil quickly. Either feed immediately or cover and storein refrigerator at 35–40°F (2–4°C) for no longer than 24 hours. Do not useprepared formula if it is unrefrigerated for more than a total of 2 hours. Do notfreeze prepared formula. After feeding begins, do not refrigerate feedingbottle/container. You must use within 1 hour or discard.

150

Powder Storage


CAUTION


This product is nutritionally incomplete. Care must be taken to provide enoughleucine to support growth, using other foods with leucine as required. Thephysician must carefully and constantly supervise the use of LMD™ with otherfoods and adjust the diet based on frequent blood tests.






J Pediatr. 1999;134:11-14.


151

LMD

™

OA™ 1

INDICATIONOA 1 is an isoleucine-, methionine-, threonine-, and valine-free, iron-fortifieddietary powder for infants and toddlers with propionic acidemia ormethylmalonic acidemia. The product provides the essential amino acids (exceptisoleucine, methionine, threonine, and valine) as well as nonessential aminoacids, carbohydrate, fat, essential fatty acids, vitamins, and minerals. OA refers toorganic acid. Use under direct and continuing supervision of a doctor.

PRODUCT FEATURES• Isoleucine-, methionine-, threonine-, and valine-free




• Vanilla scent


152


PowderCalories 500 Protein equivalent, g† 15.7

Fat, g 26Linoleic acid, mg 4500 Linolenic acid, mg 380

Carbohydrate, g 51 Vitamins/Other Nutrients




†Protein is incomplete since it does not contain the essential amino acids isoleucine,methionine, threonine, and valine.

NA=None Added

153

OA

™1


†Protein is incomplete since it does not contain the essential amino acids isoleucine,methionine, threonine, and valine.

PRODUCT FORMOA™ 1 is available in powder. For ordering information, please refer to page 214.

COMPOSITIONIngredients: Vegetable oil (palm olein, soy, coconut, and high oleic sunfloweroils), corn syrup solids, amino acids (L-alanine, L-leucine, L-lysine hydrochloride,potassium L-aspartate, L-proline, L-arginine, glycine, L-phenylalanine, L-tyrosine,L-serine, L-histidine, L-tryptophan, L-cystine), sucrose, modified corn starch,calcium phosphate, maltodextrin, and less than 1%: vitamin A palmitate, vitaminD3, vitamin E acetate, vitamin K1, thiamin hydrochloride, riboflavin, vitamin B6

hydrochloride, vitamin B12, niacinamide, folic acid, calcium pantothenate, biotin,ascorbic acid, choline chloride, inositol, magnesium oxide, ferrous sulfate, zincsulfate, manganese sulfate, cupric sulfate, potassium iodide, sodium selenite,sodium citrate, potassium citrate, potassium chloride, L-carnitine, taurine,ethyl vanillin.

PREPARATION OF FEEDINGSThe baby’s health depends on carefully following these instructions. Useonly as directed by a medical professional. Improper hygiene, preparation,dilution, use, or storage may result in severe harm. Powdered formulas arenot sterile and should not be fed to premature infants or those persons whomight have immune problems unless directed and supervised by a doctor.




154

Powder Storage


CAUTION


This product is nutritionally incomplete. Care must be taken to provide enoughisoleucine, methionine, threonine, and valine to support growth, using otherfoods with these amino acids as required. The physician must carefully andconstantly supervise the use of OA™ 1 with other foods and adjust the dietbased on frequent blood tests.






J Pediatr. 1999;134:11-14.


155

OA

™1

OA™ 2

INDICATIONOA 2 is an isoleucine-, methionine-, threonine-, and valine-free dietary powderfor the dietary management of children and adults with propionic acidemia ormethylmalonic acidemia. The product provides the essential amino acids (exceptisoleucine, methionine, threonine, and valine) as well as nonessential aminoacids, carbohydrate, fat, essential fatty acids, vitamins, and minerals. OA refers toorganic acid. Use under direct and continuing supervision of a doctor.

PRODUCT FEATURES• Isoleucine-, methionine-, threonine-, and valine-free

• Provides adequate protein, linoleic and linolenic acid, and vitamins andminerals not available from low-protein foods while supplying fewer caloriesthan OA™ 1

• The protein source is a mixture of L-amino acids optimized for blandness, freeof isoleucine, methionine, threonine, and valine

• 21 g protein equivalent*/100 g powder

• Fat comprises approximately 20% of total calories (9 g/100 g powder)

• Vanilla scent


• Mixes easily and stays in suspension well*Protein is incomplete since it does not contain the essential amino acids isoleucine,methionine, threonine, and valine.

156

NUTRIENTS†

Per 100 gramsPowder

Calories 410Protein equivalent, g‡ 21Fat, g 9



Vitamin A, IU 1430Vitamin D, IU 290Vitamin E, IU 10.2Vitamin K, mcg 41Thiamin (Vitamin B1), mcg 1200Riboflavin (Vitamin B2), mcg 980Vitamin B6, mcg 980Vitamin B12, mcg 2.4Niacin, mcg 22000Folic acid (Folacin), mcg 350Pantothenic acid, mcg 4800Biotin, mcg 49Vitamin C (Ascorbic acid), mg 49Choline, mg 102Inositol, mg 49

Taurine, mg 49Carnitine, mg 49



‡Protein is incomplete since it does not contain the essential amino acids isoleucine,methionine, threonine, and valine.

157

OA

™2

NUTRIENT FACTSProtein Equivalent (% calories)‡ 21Fat (% calories) 20Carbohydrate (% calories) 59Potential Renal Solute Load (mOsm/100g powder)1 230Gluten-Free YesLactose-Free YesGalactose-Free Yes

‡Protein is incomplete since it does not contain the essential amino acids isoleucine,methionine, threonine, and valine.

PRODUCT FORMOA™ 2 is available in powder. For ordering information, please refer to page 214.

COMPOSITIONIngredients: Corn syrup solids, sucrose, amino acids (L-alanine, L-leucine,L-lysine hydrochloride, potassium L-aspartate, L-proline, L-arginine, glycine,L-phenylalanine, L-tyrosine, L-serine, L-histidine, L-tryptophan, L-cystine), soy oil, modified corn starch, maltodextrin, calcium phosphate, sodium citrate,magnesium phosphate, and less than 1%: vitamin A palmitate, vitamin D3,vitamin E acetate, vitamin K1, thiamin hydrochloride, riboflavin, vitamin B6

hydrochloride, vitamin B12, niacinamide, folic acid, calcium pantothenate, biotin,ascorbic acid, choline chloride, inositol, ferrous sulfate, zinc sulfate, manganesesulfate, cupric sulfate, potassium iodide, sodium selenite, chromic chloride,sodium molybdate, sodium phosphate, potassium chloride, potassium citrate,L-carnitine, taurine, ethyl vanillin.

PREPARATION OF FEEDINGSConsult with patients about the correct amounts of water and powder. The patient’s health depends on carefully following these directions.

Use only as directed by a medical professional. Improper hygiene,preparation, dilution, use or storage may result in severe harm. Nutritionalpowders are not sterile and should not be fed to those persons who mighthave immune problems unless directed and supervised by a medicalprofessional.

Pour desired amount of water into a suitable container. Add powder and mix vigorously until thoroughly blended.

Failure to follow these instructions could result in severe harm. Onceprepared, product can spoil quickly. Either consume immediately or cover andstore in refrigerator at 35–40°F (2–4°C) for no longer than 24 hours. Shake wellbefore each use. Do not use prepared product if it is unrefrigerated for morethan a total of 2 hours. Do not freeze prepared product. After feeding begins, donot refrigerate the container. You must use within 1 hour or discard.

Store unopened cans at room temperature. After opening can, keep tightlycovered, store in dry area, and use contents within 1 month. Do not freezepowder. Avoid excessive heat. Use by date on can end.

Scoop

A packed level scoop contains approximately 16 g of powder.

158

CAUTION

OA™ 2 is nutritionally incomplete. Care must be taken to provide enoughisoleucine, methionine, threonine, and valine to support growth, using otherfoods with these amino acids as required. The physician must carefully andconstantly supervise use of OA 2 with other foods and adjust the diet based onfrequent blood tests.





J Pediatr. 1999;134:11-14.


159

OA

™2

PFD™ 1

INDICATIONPFD 1 is a protein- and amino acid-free product* designed with carbohydrates,vitamins, and minerals as well as the essential fatty acids for infants and toddlerswith various amino acid metabolic disorders. PFD refers to protein-free diet. PFD1 can be used as a dietary supplement supplying calories, vitamins, and minerals,or specific amounts of amino acids or protein can be added to make a completebeverage. Use under direct and continuing supervision of a doctor.*This product does contain taurine, a non-protein-building amino acid.

PRODUCT FEATURES• Protein- and amino acid-free



• Sucrose (table sugar) has been added to improve the taste of amino acids,which may be added during preparation

• Vanilla scent


160

NUTRIENTS†

Per 100 gramsPowder

Calories 530Protein equivalent, g‡ 0Fat, g 32






‡This product is nutritionally incomplete since it does not contain any protein or aminoacids.

NA=None Added

161

PFD

™1

NUTRIENT FACTSProtein (% calories)‡ 0Fat (% calories) 54Carbohydrate (% calories) 46Potential Renal Solute Load (mOsm/100 g powder)1 62Osmolality (mOsm/kg water) 210Osmolarity (mOsm/L) 189Gluten-Free YesLactose-Free YesGalactose-Free Yes

‡This product is nutritionally incomplete since it does not contain any protein or aminoacids.

PRODUCT FORMPFD™ 1 is available in powder. For ordering information, please refer to page 214.

COMPOSITIONIngredients: Vegetable oil (palm olein, soy, coconut, and high oleic sunfloweroils), corn syrup solids, modified corn starch, sucrose, calcium phosphate, sodiumcitrate, and less than 1%: vitamin A palmitate, vitamin D3, vitamin E acetate,vitamin K1, thiamin hydrochloride, riboflavin, vitamin B6 hydrochloride, vitaminB12, niacinamide, folic acid, calcium pantothenate, biotin, ascorbic acid, cholinechloride, inositol, magnesium oxide, ferrous sulfate, zinc sulfate, manganesesulfate, cupric sulfate, potassium iodide, sodium selenite, potassium citrate,potassium chloride, L-carnitine, taurine, ethyl vanillin.





Powder Storage


162

CAUTION


This product is nutritionally incomplete. Care must be taken to provide enoughprotein or amino acids to support growth, using other foods with protein asrequired. The physician must carefully and constantly supervise the use of PFD™ 1 with other foods, and adjust the diet based on frequent blood tests.






J Pediatr. 1999;134:11-14.


163

PFD

™1

PFD™ 2

INDICATIONPFD 2 is a protein- and amino acid-free product designed to help meet thecalorie, vitamin, mineral, and essential fatty acid needs of children and adultswith amino acid metabolic disorders. PFD refers to protein-free diet. PFD 2 canbe mixed with condition-specific amino acids or protein to make a nutritionallycomplete beverage or it can be used as a calorie, vitamin, and mineralsupplement when amino acid and protein requirements are met but needs forcalories, vitamins, and minerals are not. Use under direct and continuingsupervision of a doctor.

PRODUCT FEATURES• Protein- and amino acid-free

• Lactose-free

• Provides essential fatty acids

• Convenient to use for preparing individualized protein-restricted diets

• Vanilla scent



164





Vitamin A, IU 790Vitamin D, IU 154Vitamin E, IU 5.1Vitamin K, mcg 15.8Thiamin (Vitamin B1), mcg 630Riboflavin (Vitamin B2), mcg 510Vitamin B6, mcg 510Vitamin B12, mcg 1.19Niacin, mcg 11500Folic acid (Folacin), mcg 178Pantothenic acid, mcg 2600Biotin, mcg 26Vitamin C (Ascorbic acid), mg 26Choline, mg 51Inositol, mg 26Taurine, mg 26Carnitine, mg 26

MineralsCalcium, mg 400Phosphorus, mg 400Magnesium, mg 91Iron, mg 6.3Zinc, mg 6.3Manganese, mcg 590Copper, mcg 630Iodine, mcg 26Selenium, mcg 15.8Sodium, mg 360Potassium, mg 340Chloride, mg 320Molybdenum, mcg 19.8Chromium, mcg 19.8


†This product is nutritionally incomplete since it does not contain any protein or aminoacids.

165

PFD

™2

NUTRIENT FACTSProtein (% calories)† 0Fat (% calories) 11Carbohydrate (% calories) 89Gluten-Free YesLactose-Free YesGalactose-Free Yes

†This product is nutritionally incomplete since it does not contain any protein or aminoacids.

PRODUCT FORMPFD™ 2 is available in powder. For ordering information, please refer to page 214.

COMPOSITIONIngredients: Corn syrup solids, sugar, soy oil, modified corn starch, calciumphosphate, and less than 1% sodium citrate, magnesium phosphate, potassiumchloride, sodium phosphate, potassium citrate, choline chloride, L-carnitine,ascorbic acid, inositol, taurine, niacinamide, vitamin E acetate, potassium iodide,vitamin A palmitate, calcium pantothenate, biotin, vitamin K1, vitamin B12,thiamin hydrochloride, vitamin B6 hydrochloride, riboflavin, vitamin D3, folic acid,zinc sulfate, chromic chloride, sodium selenite, cupric sulfate, manganese sulfate,sodium molybdate, ferrous sulfate, ethyl vanillin.


Pour desired amount of water in a suitable container. Add powder and mix well.Consume immediately or cover and refrigerate prepared beverage. Use within48 hours. Shake well before serving.



Scoop

A packed level scoop contains 15.6 g of powder.

CAUTION

PFD 2 is nutritionally incomplete. Care must be taken to provide enough proteinto support growth, using other foods with protein as required. The physicianmust carefully and constantly supervise the use of PFD 2 with other foods andadjust the diet based on frequent blood tests.





166

Phenyl-Free® 1

INDICATIONPhenyl-Free® 1 is a phenylalanine-free, iron-fortified dietary powder for infantsand toddlers with phenylketonuria (PKU). It provides the essential amino acids(except phenylalanine) as well as nonessential amino acids, carbohydrate, fat,essential fatty acids, vitamins, and minerals. Use under direct and continuingsupervision of a doctor.

PRODUCT FEATURES• Phenylalanine-free

• Vitamin and mineral levels meet the U.S. Infant Formula Act requirement per100 Calories


• Improved taste; sucrose (table sugar) has been added to neutralize the taste ofamino acids

• Vanilla scent


167

Phenyl-Free

®1








†Protein is incomplete since it does not contain the essential amino acid phenylalanine.NA=None Added

168


†Protein is incomplete since it does not contain the essential amino acid phenylalanine.

PRODUCT FORMPhenyl-Free® 1 is available in powder. For ordering information, please refer topage 214.

COMPOSITIONIngredients: Vegetable oil (palm olein, soy, coconut and high oleic sunfloweroils), corn syrup solids, amino acids (L-glutamine, L-leucine, potassiumL-aspartate, L-lysine hydrochloride, L-tyrosine, L-proline, L-valine, L-isoleucine,L-alanine, L-arginine, L-threonine, L-serine, glycine, L-histidine, L-methionine,L-tryptophan, L-cystine), modified corn starch, sucrose, calcium phosphate,maltodextrin, and less than 1%: vitamin A palmitate, vitamin D3, vitamin Eacetate, vitamin K1, thiamin hydrochloride, riboflavin, vitamin B6 hydrochloride,vitamin B12, niacinamide, folic acid, calcium pantothenate, biotin, ascorbic acid,choline chloride, inositol, magnesium oxide, ferrous sulfate, zinc sulfate,manganese sulfate, cupric sulfate, potassium iodide, sodium selenite, sodiumcitrate, potassium citrate, potassium chloride, L-carnitine, taurine, ethyl vanillin.





169

Phenyl-Free

®1

Powder Storage

Store cans at room temperature. After opening can, keep tightly covered, store in a dry area, and use contents within 1 month. Do not freeze powder or prepared formula. Avoid excessive heat. Use by date on can end.

CAUTION


This product is nutritionally incomplete. Care must be taken to provide enoughphenylalanine to support growth, using other foods with phenylalanine asrequired. The physician must carefully and constantly supervise the use ofPhenyl-Free® 1 with other foods and adjust the diet based on frequent bloodtests.






J Pediatr. 1999;134:11-14.


170

Phenyl-Free® 2

INDICATIONPhenyl-Free® 2 is a phenylalanine-free dietary powder for children and adults with phenylketonuria (PKU). It provides the essential amino acids (exceptphenylalanine) as well as nonessential amino acids, carbohydrate, fat, essentialfatty acids, vitamins, and minerals. Phenyl-Free 2 has less fat and fewer totalcalories than Phenyl-Free 1. Use under direct and continuing supervision of a doctor.



• Higher level of protein equivalents than found in Phenyl-Free 1

• Lactose-free

• Vanilla scent



171

Phenyl-Free

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PRODUCT FORMPhenyl-Free® 2 is available in powder. For ordering information, please refer topage 214.

COMPOSITIONIngredients: Sugar, amino acids (L-glutamine, L-leucine, potassium aspartate,L-lysine hydrochloride, L-tyrosine, L-proline, L-valine, L-isoleucine, L-alanine,L-arginine, L-threonine, L-serine, glycine, L-histidine, L-methionine, L-tryptophan,L-cystine), corn syrup solids, soy oil, modified corn starch, calcium phosphate,sodium citrate, magnesium phosphate and less than 1%: potassium chloride,sodium phosphate, potassium citrate, choline chloride, L-carnitine, ascorbic acid,inositol, taurine, niacinamide, vitamin E acetate, potassium iodide, vitamin Apalmitate, calcium pantothenate, biotin, vitamin K1, vitamin B12, thiamin hydro-chloride, vitamin B6 hydrochloride, riboflavin, vitamin D3, folic acid, zinc sulfate,chromic chloride, sodium selenite, cupric sulfate, manganese sulfate, sodiummolybdate, ferrous sulfate, ethyl vanillin.





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CAUTION

Phenyl-Free® 2 is nutritionally incomplete. Care must be taken to provide enoughphenylalanine to support growth, using other foods with these amino acids asrequired. The physician must carefully and constantly supervise the use ofPhenyl-Free 2 with other foods and adjust the diet based on frequent bloodtests.





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Phenyl-Free® 2 HP

INDICATIONPhenyl-Free® 2 HP is a high protein equivalent, phenylalanine-free dietarypowder for children and adults with phenylketonuria (PKU). It provides theessential amino acids (except phenylalanine) as well as nonessential amino acids,carbohydrate, fat, essential fatty acids, vitamins, and minerals. Phenyl-Free 2 HPis higher in protein equivalents and most vitamins and minerals than Phenyl-Free® 2. Phenyl-Free 2 HP is appropriate for women with maternal PKU or forchildren and adults who require fewer calories than provided by Phenyl-Free 2.Use under direct and continuing supervision of a doctor.



• Higher level of protein equivalents than found in Phenyl-Free 2

• Lactose-free

• Vanilla scent



• Higher levels of most vitamins and minerals than found in Phenyl-Free 2(Note: Due to the higher levels of amino acids in Phenyl-Free 2 HP, the taste of aminoacids is more prevalent in this product than it is in Phenyl-Free 2.)

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PRODUCT FORMPhenyl-Free® 2 HP is available in powder. For ordering information, please referto page 214.

COMPOSITIONIngredients: Amino acids (L-glutamine, L-leucine, potassium aspartate, L-lysinehydrochloride, L-tyrosine, L-proline, L-valine, L-isoleucine, L-alanine, L-arginine,L-threonine, L-serine, glycine, L-histidine, L-methionine, L-tryptophan, L-cystine),sugar, corn syrup solids, soy oil, modified corn starch, calcium phosphate,magnesium phosphate, sodium citrate and less than 1%: potassium chloride,sodium phosphate, potassium citrate, choline chloride, L-carnitine, ascorbic acid,inositol, taurine, niacinamide, vitamin E acetate, potassium iodide, vitamin Apalmitate, calcium pantothenate, biotin, vitamin K1, vitamin B12, thiaminhydrochloride, vitamin B6 hydrochloride, riboflavin, vitamin D3, folic acid, zincsulfate, chromic chloride, sodium selenite, cupric sulfate, manganese sulfate,sodium molybdate, ferrous sulfate, ethyl vanillin.





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CAUTION

Phenyl-Free® 2 HP is nutritionally incomplete. Care must be taken to provideenough phenylalanine to support growth, using other foods with this amino acidas required. The physician must carefully and constantly supervise the use ofPhenyl-Free 2 HP with other foods and adjust the diet based on frequent bloodtests.





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TYROS™ 1

INDICATIONTYROS 1 is a phenylalanine- and tyrosine-free, iron-fortified dietary powder forinfants and toddlers with tyrosinemia. This product provides the essential aminoacids (except phenylalanine and tyrosine) as well as nonessential amino acids,carbohydrate, fat, essential fatty acids, vitamins, and minerals. Use under directand continuing supervision of a doctor.

PRODUCT FEATURES• Phenylalanine- and tyrosine-free



• Improved taste; sucrose (table sugar) has been added to neutralize the taste ofamino acids

• Vanilla scent


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†Protein is incomplete since it does not contain the essential amino acids tyrosine andphenylalanine.

NA=None Added

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†Protein is incomplete since it does not contain the essential amino acids tyrosine andphenylalanine.

PRODUCT FORMTYROS™ 1 is available in powder. For ordering information, please refer to page214.

COMPOSITIONIngredients: Vegetable oil (palm olein, soy, coconut, and high oleic sunfloweroils), corn syrup solids, amino acids (L-glutamine, L-leucine, potassiumL-aspartate, L-lysine hydrochloride, L-proline, L-valine, L-alanine, L-isoleucine,L-arginine, L-threonine, L-serine, glycine, L-histidine, L-methionine, L-tryptophan,L-cystine), modified corn starch, sucrose, calcium phosphate, maltodextrin, andless than 1%: vitamin A palmitate, vitamin D3, vitamin E acetate, vitamin K1,thiamin hydrochloride, riboflavin, vitamin B6 hydrochloride, vitamin B12,niacinamide, folic acid, calcium pantothenate, biotin, ascorbic acid, cholinechloride, inositol, magnesium oxide, ferrous sulfate, zinc sulfate, manganesesulfate, cupric sulfate, potassium iodide, sodium selenite, sodium citrate,potassium citrate, potassium chloride, L-carnitine, taurine, ethyl vanillin.





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Powder Storage

Store cans at room temperature. After opening can, keep tightly covered, storein a dry area, and use contents within 1 month. Do not freeze powder orprepared formula. Avoid excessive heat. Use by date on can end.

CAUTION


This product is nutritionally incomplete. Care must be taken to provide enoughphenylalanine and tyrosine to support growth, using other foods with theseamino acids as required. The physician must carefully and constantly supervisethe use of TYROS™ 1 with other foods and adjust the diet based on frequentblood tests.






J Pediatr. 1999;134:11-14.


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TYROS™ 2

INDICATIONTYROS 2 is a phenylalanine- and tyrosine-free dietary powder for children andadults with inborn errors of tyrosine metabolism including tyrosinemia type II.The product provides the essential amino acids (except phenylalanine andtyrosine) as well as nonessential amino acids, carbohydrate, fat, essential fattyacids, vitamins, and minerals. Use under direct and continuing supervision of adoctor.

PRODUCT FEATURES• Phenylalanine- and tyrosine-free


• Higher level of protein equivalents than found in TYROS™ 1

• Lactose-free

• Vanilla scent




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†Protein is incomplete since it does not contain the essential amino acids phenylalanineand tyrosine.

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†Protein is incomplete since it does not contain the essential amino acids phenylalanineand tyrosine.

PRODUCT FORMTYROS™ 2 is available in powder. For ordering information, please refer to page214.

COMPOSITIONIngredients: Corn syrup solids, amino acids (L-glutamine, L-leucine, potassiumaspartate, L-lysine hydrochloride, L-proline, L-valine, L-isoleucine, L-alanine,L-arginine, L-threonine, L-serine, glycine, L-histidine, L-methionine, L-tryptophan,L-cystine), sugar, soy oil, modified corn starch, calcium phosphate, sodiumcitrate, magnesium phosphate and less than 1%: potassium chloride, sodiumphosphate, potassium citrate, choline chloride, L-carnitine, ascorbic acid, inositol,taurine, niacinamide, vitamin E acetate, potassium iodide, vitamin A palmitate,calcium pantothenate, biotin, vitamin K1, vitamin B12, thiamin hydrochloride,vitamin B6 hydrochloride, riboflavin, vitamin D3, folic acid, zinc sulfate, chromicchloride, sodium selenite, cupric sulfate, manganese sulfate, sodium molybdate,ferrous sulfate, ethyl vanillin.


Pour desired amount of water in a suitable container. Add powder and mix well.Consume immediately or cover and refrigerate prepared beverage. Use within48 hours. Shake well before serving.



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CAUTION

TYROS™ 2 is nutritionally incomplete. Care must be taken to provide enoughphenylalanine and tyrosine to support growth, using other foods with theseamino acids as required. The physician must carefully and constantly supervisethe use of TYROS 2 with other foods and adjust the diet based on frequentblood tests.





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WND® 1

INDICATIONWND 1 is a nonessential amino acid-free, iron-fortified dietary powder for infantsand toddlers with inborn errors of the urea cycle. The product provides theessential amino acids as well as carbohydrate, fat, essential fatty acids, vitamins,and minerals. WND refers to waste nitrogen disorders. Use under direct andcontinuing supervision of a doctor.

PRODUCT FEATURES • Nonessential amino acid-free




• Vanilla scent


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†Protein level is inadequate to meet normal infant growth and development needs usingWND® 1 alone.

NA=None Added

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NUTRIENTS FACTSProtein Equivalent (% calories)† 5Fat (% calories) 47Carbohydrate (% calories) 48Potential Renal Solute Load (mOsm/100 g powder)1 88Osmolality (mOsm/kg water) 280Osmolarity (mOsm/L) 250Gluten-Free YesLactose-Free YesGalactose-Free Yes

†Protein level is inadequate to meet normal infant growth and development needs usingWND® 1 alone.

PRODUCT FORMWND 1 is available in powder. For ordering information, please refer to page 214.

COMPOSITIONIngredients: Corn syrup solids, vegetable oil (palm olein, soy, coconut and higholeic sunflower oils), sucrose, modified corn starch, amino acids (L-leucine,L-lysine hydrochloride, L-isoleucine, L-valine, L-threonine, L-tyrosine, L-phenyl-alanine, L-histidine, L-tryptophan, L-methionine, L-cystine), calcium phosphate,potassium citrate, and less than 1%: vitamin A palmitate, vitamin D3, vitamin Eacetate, vitamin K1, thiamin hydrochloride, riboflavin, vitamin B6 hydrochloride,vitamin B12, niacinamide, folic acid, calcium pantothenate, biotin, ascorbic acid,choline chloride, inositol, magnesium oxide, ferrous sulfate, zinc sulfate,manganese sulfate, cupric sulfate, potassium iodide, sodium selenite, sodiumcitrate, potassium citrate, potassium chloride, L-carnitine, taurine, ethyl vanillin.





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Powder Storage

Store cans at room temperature. After opening can, keep tightly covered, storein a dry area, and use contents within 1 month. Do not freeze powder orprepared formula. Avoid excessive heat. Use by date on can end.

CAUTION


This product is nutritionally incomplete. Care must be taken to provide enoughcalories and protein to support growth, using other foods as required. Thephysician must carefully and constantly supervise the use of WND® 1 with otherfoods and adjust the diet based on frequent blood tests.






J Pediatr. 1999;134:11-14.


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WND® 2

INDICATIONWND 2 is a dietary powder that is free of nonessential amino acids for childrenand adults with inborn errors of the urea cycle. The product provides theessential amino acids, carbohydrate, fat, essential fatty acids, vitamins, andminerals. WND refers to waste nitrogen disorder. Use under direct andcontinuing supervision of a doctor.

PRODUCT FEATURES• Provides essential amino acids; does not contain nonessential amino acids

• 8.2 g protein equivalents/100 g powder

• Lactose-free

• Vanilla scent




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PowderCalories 410Protein equivalent, g† 8.2Fat, g 10.2






†Care must be taken to provide enough calories, vitamins and minerals using otherfoods to support growth as required.

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NUTRIENT FACTSProtein Equivalent (% calories) 8Fat (% calories) 23Carbohydrate (% calories) 69Gluten-Free YesLactose-Free YesGalactose-Free Yes

PRODUCT FORMWND® 2 is available in powder. For ordering information, please refer to page 214.

COMPOSITIONIngredients: Corn syrup solids, sugar, amino acids (L-leucine, L-lysinehydrochloride, L-isoleucine, L-valine, L-threonine, L-tyrosine, L-phenylalanine,L-histidine, L-tryptophan, L-methionine, L-cystine), soy oil, modified corn starch,calcium phosphate, sodium citrate, magnesium phosphate, potassium chloride,potassium citrate, and less than 1%: sodium phosphate, choline chloride,L-carnitine, ascorbic acid, inositol, taurine, niacinamide, vitamin E acetate,potassium iodide, vitamin A palmitate, calcium pantothenate, biotin, vitamin K1,vitamin B12, thiamin hydrochloride, vitamin B6 hydrochloride, riboflavin, vitaminD3, folic acid, ferrous sulfate, zinc sulfate, chromic chloride, sodium selenite,cupric sulfate, manganese sulfate, sodium molybdate, ethyl vanillin.

PREPARATION OF FEEDINGSConsult with patients about the correct amounts of water and powder.




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CAUTION


WND 2 is nutritionally incomplete. Care must be taken to provide enoughcalories, vitamins, and minerals to support growth, using other foods as required.The physician must carefully and constantly supervise the use of WND 2 withother foods and adjust the diet based on frequent blood tests.





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DietarySupplements

Enfamil®D-Vi-Sol™ DropsVitamin D Supplement

INDICATIONVitamin D supplement for infants and children.

The American Academy of Pediatrics (AAP) recommends 400 IU of supplementalvitamin D supplement per day for all breastfed and partially breastfed infantswho do not receive at least 1L of infant formula per day.1

RATIONALE AND SPECIAL CHARACTERISTICSEnfamil D-Vi-Sol drops provide 400 IU of vitamin D to meet the recommendedvitamin D intake levels. With a sweet, citrus taste, D-Vi-Sol is sugar-free, gluten-free, and lactose-free.

OSMOLALITYWhen added to 2 fl oz of infant formula or breast milk, 1 mL of Enfamil D-Vi-Solincreases the osmolality by +110 mOsmol/kg water.2 If the resulting osmolality ishigher than desired for a particular baby, an option is to add 0.5 mL of thesupplement to the feeding twice per day.

NUTRIENTSDrops (per mL)

Per 1 mL % DV Infants % DV Children under age 4 years

Vitamin D, IU 400 100 100

PRODUCT FORMEnfamil D-Vi-Sol is available in drops. For ordering information, please refer topage 214.

Usual Daily DoseDrops: 1.0 mL

COMPOSITIONIngredients: Glycerin, water, polysorbate 80, citric acid, vitamin D3, sodiumcitrate, sodium hydroxide, artificial flavor and artificial caramel color.

ADMINISTRATIONDrops: The dropper is marked with 0.5 mL and 1.0 mL dose lines. To administerdirectly, place the dropper in the child’s mouth with the tip against the inside ofthe cheek. A firm pressure on the dropper bulb will deliver the proper dose. Aslight excess will remain in the dropper. If preferred, the drops may be slowlymixed with formula, juice, cereal, or other food and fed within one hour.

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PRECAUTIONSAs with all vitamin products, parents should be cautioned against excessivedosage. The bottle should be kept out of the reach of children.

REFERENCES1. Wagner CL, Greer FR, and the Section on Breastfeeding and Committee on Nutrition.

Prevention of Rickets and Vitamin D Deficiency in Infants, Children, and Adolescents.Pediatrics 2008;122:1142-1152.

2. Testing was conducted in September 2009 by Mead Johnson Nutrition, QualityControl.


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Enfamil®Poly-Vi-Sol® DropsMultivitamin Supplement

INDICATIONMultivitamin supplementation for infants and children.


Note: Poly-Vi-Sol Drops do not include folic acid.

RATIONALE AND SPECIAL CHARACTERISTICSEnfamil Poly-Vi-Sol multivitamin supplement drops provide 9 important vitaminsand are an ideal supplement for a child’s transition to solid foods, during growthspurts, and for the picky eater. They are fruit-flavored, lactose-free, gluten-free,and free of artificial sweeteners.

Refrigeration is not required.

OSMOLALITYWhen added to 2 fl oz of infant formula or breast milk, 1 mL of Enfamil Poly-Vi-Sol increases the osmolality by +160 mOsmol/kg water.2 If the resultingosmolality is higher than desired for a particular baby, an option is to add 0.5 mLof the supplement to the feeding twice per day.

NUTRIENTS% DV

Enfamil % DV Infants under Poly-Vi-Sol Infants 4 years

Vitamin A, IU 1500 100 60Vitamin D, IU 400 100 100Vitamin E, IU 5 100 50Vitamin C, mg 35 100 88Thiamin, mg 0.5 100 71Riboflavin, mg 0.6 100 75Niacin, mg 8 100 89Vitamin B6, mg 0.4 100 57Vitamin B12, mcg 2 100 67Sizes 50 mL

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PRODUCT FORMEnfamil® Poly-Vi-Sol® is available in drops. For ordering information, please referto page 214.

Usual Daily Dose

Drops: 1.0 mL

COMPOSITIONIngredients: Glycerin, water, ascorbic acid, polysorbate 80, vitamin E succinate,niacinamide, ferrous sulfate (as a stabilizer for vitamin B12), natural and artificialflavor, artificial caramel color, vitamin A palmitate, thiamin hydrochloride,riboflavin-5-phosphate sodium, vitamin B6 hydrochloride, vitamin D3, vitamin B12.




Prevention of Rickets and Vitamin D Deficiency in Infants, Children, and Adolescents.Pediatrics 2008;122:1142-1152.



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Enfamil® Poly-Vi-Sol®with Iron DropsMultivitamin Supplement

INDICATIONMultivitamin and iron supplementation for infants and children.


Infants who may especially require supplemental iron include infants of anemicmothers,2 low-birth-weight infants,2,3,4 and infants of mothers with poorlycontrolled diabetes.2

RATIONALE AND SPECIAL CHARACTERISTICSEnfamil® Poly-Vi-Sol® multivitamin and iron supplement drops have iron plus 8important vitamins for convenient daily dosage and are an ideal supplement fora child’s transition to solid foods, during growth spurts, and for the picky eater.They are fruit-flavored, lactose-free, gluten-free, and free of artificial sweeteners.


OSMOLALITYWhen added to 2 fl oz of infant formula or breast milk, 1 mL of Enfamil Poly-Vi-Sol with Iron increases the osmolality by +160 mOsmol/kg water.5 If the resultingosmolality is higher than desired for a particular baby, an option is to add 0.5 mLof the supplement to the feeding twice per day.

NUTRIENTS% DV

Enfamil % DV Infants under Poly-Vi-Sol with Iron Infants 4 years

Vitamin A, IU 1500 100 60Vitamin D, IU 400 100 100Vitamin E, IU 5 100 50Vitamin C, mg 35 100 88Thiamin, mg 0.5 100 71Riboflavin, mg 0.6 100 75Niacin, mg 8 100 89Vitamin B6, mg 0.4 100 57Elemental Iron, mg 10* 67 100Sizes 50 mL

*From 50 mg ferrous sulfate heptahydrate.

Note: Enfamil Poly-Vi-Sol Drops with Iron do not include folic acid.

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Enfamil® Poly-Vi-Sol® with Iron Drops do not include vitamin B12 since it isunstable in a solution that has the concentrations of iron and vitamin C found inPoly-Vi-Sol with Iron Drops.

PRODUCT FORMEnfamil Poly-Vi-Sol with Iron is available in drops. For ordering information,please refer to page 214.


COMPOSITIONIngredients: Glycerin, water, ascorbic acid, ferrous sulfate, vitamin E succinate,niacinamide, natural and artificial flavor, artificial caramel color, polysorbate 80,vitamin A palmitate, thiamin hydrochloride, riboflavin-5-phosphate sodium,vitamin B6 hydrochloride, vitamin D3.

ACCIDENTAL OVERDOSAGE OR INTAKEIn case of accidental overdose, the physician, Poison Control Center, or hospitalemergency should be notified immediately. Patients with a known exposure ofmore than 40 mg/kg of elemental iron, or with severe, persistent symptomsrelated to iron ingestion, should be referred to a healthcare facility formedical evaluation and observation.5 The vitamin ingredients would not beexpected to cause ill effects from a one-time overdose.

WARNING: Accidental overdose of iron-containing products is a leadingcause of fatal poisoning in children under 6. Keep this product out of thereach of children.



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Prevention of Rickets and Vitamin D Deficiency in Infants, Children, and Adolescents.Pediatrics. 2008;122:1142-1152.

2. American Academy of Pediatrics, Committee on Nutrition. Kleinman RE, ed. PediatricNutrition Handbook. 6th ed. Elk Grove Village, Ill: AAP; 2009:414-415.

3. American Academy of Pediatrics, Section on Breastfeeding. Breastfeeding and the useof human milk. Pediatrics. 2005;115:496-506.




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Enfamil®Tri-Vi-Sol® DropsVitamins A, C, and D Supplement

INDICATIONVitamins A, C, and D supplementation.


RATIONALE AND SPECIAL CHARACTERISTICSEnfamil Tri-Vi-Sol vitamin drops provide 3 frequently prescribed vitamins inamounts suitable for daily administration to infants. Enfamil Tri-Vi-Sol vitamindrops are fruit-flavored, lactose-free, gluten-free, and free of artificial sweeteners.


OSMOLALITYWhen added to 2 fl oz of infant formula or breast milk, 1 mL of Enfamil Tri-Vi-Solincreases the osmolality by +115 mOsmol/kg water.2 If the resulting osmolality ishigher than desired for a particular baby, an option is to add 0.5 mL of thesupplement to the feeding twice per day.

NUTRIENTS% DV

Enfamil % DV Children under Tri-Vi-Sol Infants age 4 years

Vitamin A, IU 1500 100 60Vitamin D, IU 400 100 100Vitamin C, mg 35 100 88Sizes 50 mL

PRODUCT FORMEnfamil Tri-Vi-Sol is available in drops. For ordering information, please refer topage 214.


COMPOSITIONIngredients: Glycerin, water, polysorbate 80, ascorbic acid, natural and artificialflavor, artificial caramel color, vitamin A palmitate, vitamin D3.

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Enfamil® Tri-Vi-Sol®with Iron DropsVitamins A, C, and D Supplement

INDICATIONVitamins A, C, D, and iron supplementation.


Infants who may especially require supplemental iron include infants ofpremature and low-birth-weight infants,2,3,4 and infants of mothers with poorlycontrolled diabetes.2

RATIONALE AND SPECIAL CHARACTERISTICSEnfamil Tri-Vi-Sol with Iron Drops provide supplemental iron plus 3 vitamins forconvenient daily dosage. The drops are fruit-flavored, lactose-free, gluten-free,and free of artificial sweeteners. Refrigeration is not required.

OSMOLALITYWhen added to 2 fl oz of infant formula or breast milk, 1 mL of Enfamil Tri-Vi-Solwith Iron increases the osmolality by +115 mOsmol/kg water.5 If the resultingosmolality is higher than desired for a particular baby, an option is to add 0.5 mLof the supplement to the feeding twice per day.

NUTRIENTS% DV

Enfamil Tri-Vi-Sol % DV Children under with Iron Infants age 4 years

Vitamin A, IU 1500 100 60Vitamin D, IU 400 100 100Vitamin C, mg 35 100 88Elemental Iron, mg 10* 67 100Sizes 50 mL

*From 50 mg ferrous sulfate heptahydrate.

PRODUCT FORMEnfamil Tri-Vi-Sol with Iron is available in drops. For ordering information, pleaserefer to page 214.


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COMPOSITIONIngredients: Glycerin, water, propylene glycol, polysorbate 80, ascorbic acid,ferrous sulfate, natural and artificial flavor, artificial caramel color, vitamin Apalmitate, vitamin D3.

ACCIDENTAL OVERDOSAGE OR INTAKEIn case of accidental overdose, the physician, Poison Control Center, or hospitalemergency should be notified immediately. Patients with a known exposure ofmore than 40 mg/kg of elemental iron, or with severe, persistent symptomsrelated to iron ingestion, should be referred to a healthcare facility formedical evaluation and observation.5 The vitamin ingredients would not beexpected to cause ill effects from a one-time overdose.







3. American Academy of Pediatrics, Section on Breastfeeding. Breastfeeding and the useof human milk. Pediatrics. 2005;115:496-506.




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Enfamil® Fer-In-Sol®Iron SupplementFor the supplemental iron needs of:

• Infants

• Children

INDICATIONDosage forms are appropriate to provide supplementary iron needs for infantsand children. Infants who may especially require supplemental iron includeinfants of anemic mothers,1,2 low-birth-weight infants,1,3,4 and infants of motherswith poorly controlled diabetes.5

OSMOLALITYWhen added to 2 fl oz of infant formula or breast milk, 1 mL of Enfamil Fer-In-SolIron Supplement Drops increases the osmolality by +55 mOsmol/kg water.6 If theresulting osmolality is higher than desired for a particular baby, an option is toadd 0.5 mL of the supplement to the feeding twice per day.

SIDE EFFECTSWhile taking iron, stools may appear darker in color. This is normal and no causefor concern. When taking iron drops, temporary discoloration of teeth ordentures may occur. The discoloration can be minimized by thorough brushingand will gradually disappear after iron therapy is completed. For infants, a smallamount of baking soda or non-fluoridated tooth powder, placed on a small clothand rubbed on the teeth once a week, will minimize this temporary discoloration.

NUTRIENTS% Daily Value (DV)

Ferrous Elemental ChildrenDosage Sulfate, mg Iron, mg Infants under 40.5 mL 37.5 7.5 50 751.0 mL 75 15 100 150

Source of iron is ferrous sulfate heptahydrate.

PRODUCT FORMEnfamil® Fer-In-Sol® is available in drops. For ordering information, please referto page 214.

Usual Daily DoseDrops: 1.0 mL or as prescribed.

COMPOSITION Ingredients: Water, sugar, sorbitol, ferrous sulfate, citric acid, alcohol (0.2% v/v),sodium bisulfite (preservative), and natural flavors.

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ACCIDENTAL OVERDOSAGE OR INTAKEIn case of accidental overdose, the physician, Poison Control Center, or hospitalemergency should be notified immediately. Patients with a known exposure ofmore than 40 mg/kg of elemental iron, or with severe, persistent symptomsrelated to iron ingestion, should be referred to a healthcare facility formedical evaluation and observation.


ADMINISTRATIONDrops: The dropper is marked with 0.5 mL and 1.0 mL dose lines. To administerdirectly, place the dropper in the child’s mouth with the tip against the inside ofthe cheek. A firm pressure on the dropper bulb will deliver the proper dose.

PRECAUTIONSAs with all products providing iron, parents should be warned against excessivedosage.

REFERENCES1. American Academy of Pediatrics, Section on Breastfeeding. Breastfeeding and the use

of human milk. Pediatrics. 2005;115:496-506.2. Food and Nutrition Board, Institute of Medicine. Calcium. Iron In: Dietary Reference

Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron,Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC:National Academy Press; 2001.


4. American Academy of Pediatrics, Committee on Nutrition. Iron fortification of infant formulas. Pediatrics. 1999;104:119-123.

5. Manoguerra AS, Erdman AR, Booze LL, et al for the American Association of Poison Control Centers. Iron ingestion: an evidence-based consensus guideline forout-of-hospital management. Clin Toxicol (Phila). 2005;43:553-570.

6. Data on File. Mead Johnson Nutrition, Sep 2009.


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Expecta® LIPIL®

DHA SupplementFor Pregnant and Nursing Moms

INDICATIONExpecta LIPIL DHA Supplement is for pregnant and nursing women. It helpssupply the DHA their diet may lack. For adults only. The patient should consulther doctor before taking any supplement. Docosahexaenoic acid (DHA) is anomega-3 fatty acid that is an important structural element of the brain andretina.* In fact, DHA is a component needed for baby’s brain and eyedevelopment.*

*These statements have not been evaluated by the Food and Drug Administration.This product is not intended to diagnose, treat, cure, or prevent any disease.

PRODUCT FEATURES • A dietary supplement supplying 200 mg of DHA

• An easy-to-swallow softgel capsule

• 30-count blister pack for ease of use and portability

• A non-fish-based source of DHA

• Complements most prenatal vitamins

• Supplementation with a biologically equivalent DHA oil increased DHA bloodlevels in pregnant women1 and in the milk levels2,3 and blood levels of lactatingwomen3 and their babies.2 This may help support structural development oftheir babies’ brain and eyes.

• Formulated with a hint of lemon designed to help reduce potential aftertaste

DHA INTAKES• While a daily value for DHA has not been established, expert panels have

recommended at least 200 mg DHA/day for pregnant and nursing women.4,5

• The average intake of DHA by pregnant or nursing women in the U.S. is about54 mg/day.6

• Dietary DHA sources include foods such as salmon, tuna, and other fatty fish.The FDA and EPA have advised pregnant and nursing women to avoid certainfish due to mercury levels, and to eat up to 12 ounces per week of a variety offish and shellfish that are lower in mercury.

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SUPPLEMENT FACTSServing Size1 softgel Amount Per Serving % DVCalories 5 –Total Fat 0.5 g †DHA‡ 200 mg †

†Daily value not established.‡Docosahexaenoic acid from Schizochytrium sp. oil.

DOSAGEOne softgel daily with a meal.

Swallow whole with water.

PRODUCT CHARACTERISTICS• All-natural non-fish source (not from fish oil)

• The DHA source accepted as GRAS (Generally Recognized as Safe) by the U.S.Food and Drug Administration7,8 for use in infant formula

• Free of environmental pollutants and toxins

PRODUCT FORMExpecta® LIPIL® is available in softgel capsules. For ordering information, pleaserefer to page 214.

COMPOSITIONIngredients: DHA (docosahexaenoic acid from Schizochytrium sp. oil) 200 mg.

Other Ingredients: Gelatin, glycerin, high oleic sunflower oil, water, lemon oil,soy lecithin, rosemary extract, colors (carmine and turmeric), ascorbyl palmitate(antioxidant), and mixed natural tocopherols (antioxidants).

CAUTION

Store at room temperature in a dry place.

Protect from excessive heat or freezing.

Keep out of the reach of children.

REFERENCES1. Otto SJ, van Houwelingen AC, Hornstra G. The effect of supplementation with

docosahexaenoic and arachidonic acid derived from single cell oils on plasma anderythrocyte fatty acids of pregnant women in the second trimester. ProstaglandinsLeukot Essent Fatty Acids. 2000;63:323-328.

2. Jensen CL, Voigt RG, Prager TC, et al. Effects of maternal docosahexaenoic acidintake on visual function and neurodevelopment in breast-fed term infants. Am J ClinNutr. 2005;82:125-132.

3. Makrides M, Neumann MA, Gibson RA. Effect of maternal docosahexaenoic acid(DHA) supplementation on breast milk composition. Eur J Clin Nutr. 1996;50:352-357.

4. Simpopoulos AP, Leaf A, Salem N Jr. Workshop of the essentiality of andrecommended dietary intakes for omega-6 and omega-3 fatty acids. J Am Coll Nutr.1999;18:487-489.

5. Koletzko BV, Cetin I, Brenna JT. Consensus recommendations of dietary fat intakeduring pregnancy and lactation [abstract]. FASEB J. 2007;21:541.17.

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6. Benisek D, Shabert J, Skornik R. Dietary intake of polyunsaturated fatty acids bypregnant or lactating women in the United States [abstract]. Obstet Gynecol.2000;95(suppl):77S-78S.

7. U.S. Food and Drug Administration Center for Food Safety and Applied Nutrition web site. Agency response letter GRAS Notice No. GRN 000041. Available at:http://www.cfsan.fda.gov/~rdb/opa-g041.html. Accessed December 21, 2009.

8. U.S. Food and Drug Administration Center for Food Safety and Applied Nutrition web site. Agency response letter GRAS Notice No. GRN 000080. Available at:http://www.cfsan.fda.gov/~rdb/opa-g080.html. Accessed December 21, 2009.


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AdditionalProductInformation

Product Ordering Guide

212

When using this information, please note the following:Coding systems and reimbursement allowable rates vary by payer:

• Medicare Part B uses HCPCS (Healthcare Common Procedure Coding System) to group products.• Medicaid systems vary by state; some use HCPCS while others use NDC (National Drug Code)

format codes or systems of their own. Contact your state provider for more information.• Private health insurance and managed care companies may use HCPCS, NDC, or their own

system. Contact your provider for more information.

Item # Product Description Unit Size Calories/Unit Unit (fl oz) Case HCPCS Code NDC #

INFANT FORMULAS

020102 Enfamil A.R.® Powder 12.9 oz can 1860 93 6 cans per case B4158 0087-020142020119 Enfamil A.R. Powder 24 oz can 3460 173 4 cans per case B4158 0087-020159020333 Enfamil A.R. RTU 32 fl oz can 640 32 6 cans per case B4158 0087-020373145301 Enfamil A.R. RTU 2 fl oz bottle 40 2 48 bottles per case B4158 0087-145341001904 Enfamil® EnfaCare® Powder 12.8 oz can 1800 82 6 cans per case B4160 0087-001944139001 Enfamil EnfaCare RTU 2 fl oz bottle 44 2 48 bottles per case B4160 0087-139041128701 Enfamil EnfaCare RTU 32 fl oz can 700 32 6 cans per case B4160 0087-128741869302 Enfamil® Gentlease® Powder 12 oz can 1720 86 6 cans per case B4158 0087-869342869303 Enfamil Gentlease Powder 24 oz can 3440 172 4 cans per case B4158 0087-869343146401 Enfamil Gentlease RTU 2 fl oz bottle 40 2 48 bottles per case B4158 0087-1464-41139401 Enfamil® Premature Low Iron RTU, 20 Cal 2 fl oz bottle 40 2 48 bottles per case B4160 0087-139441139101 Enfamil Premature Low Iron RTU, 24 Cal 2 fl oz bottle 48 2 48 bottles per case B4160 0087-139141139201 Enfamil Premature Iron Fortified RTU, 20 Cal 2 fl oz bottle 40 2 48 bottles per case B4160 0087-139241139301 Enfamil Premature Iron Fortified RTU, 24 Cal 2 fl oz bottle 48 2 48 bottles per case B4160 0087-139341138801 Enfamil® LIPIL® RTU, 24 Cal 2 fl oz bottle 48 2 48 bottles per case B4158 0087-138841136701 Enfamil® PREMIUM™ Concentrate 13 fl oz can 5136502 Enfamil PREMIUM Powder 12.5 oz can 1800 90 6 cans per case B4158 0087-136542136501 Enfamil PREMIUM Powder 23.4 oz can 3340 167 6 cans per case B4158 0087-136541136511 Enfamil PREMIUM Powder 32.6 oz box 4660 233 4 boxes per carton B4158 0087-136551145901 Enfamil PREMIUM RTU 8 fl oz cans (4 per carton) 640 32 4 cartons per case B4158 0087-145941145902 Enfamil PREMIUM RTU 32 fl oz can 640 32 6 cans per case B4158 0087-145942136601 Enfamil PREMIUM RTU 2 fl oz bottle (6 per carton) 240 12 8 cartons per case B4158 0087-136641145801 Enfamil PREMIUM RTU 6 fl oz bottle 1136505 Enfamil PREMIUM Single-Serve Powder Packets 17.4 g stick packs (16 per carton) 1410 70 6 cartons per case B4158 0087-136545119501 Enfamil® ProSobee® Concentrate 13 fl oz can 5030911 Enfamil ProSobee RTU 8 fl oz can (4 per carton) 640 32 4 cartons per case B4159 0087-030951030934 Enfamil ProSobee RTU 32 fl oz can 640 32 6 cans per case B4159 0087-030974121401 Enfamil ProSobee Powder 12.9 oz can 1840 92 6 cans per case B4159 0087-121441121402 Enfamil ProSobee Powder 25.7 oz can 3144901 Enfamil ProSobee RTU 2 fl oz bottle 40 2 48 bottles per case B4159 0087-144941026106 Enfamil ProSobee RTU 6 fl oz bottle 120 6 24 bottles per case B4159 0087-026124020123 Enfamil® RestFull™ Powder 12.5 oz can (354 g) 1128901 Enfaport® RTU, 30 Cal 8 fl oz can 240 8 24 cans per case B4160 0087-128941049811 Nutramigen® Concentrate 13 fl oz can 520 26 12 cans per case B4161 0087-049801049911 Nutramigen RTU 32 fl oz can 640 32 6 cans per case B4161 0087-049901143701 Nutramigen RTU 2 fl oz bottle 40 2 48 bottles per case B4161 0087-143741026306 Nutramigen RTU 6 fl oz bottle 120 6 24 bottles per case B4161 0087-026324129009 Nutramigen® AA™ Powder 14.1 oz can (400 g) 1960 98 4 cans per case B4161 0087-120049123901 Nutramigen® with Enflora™ LGG®* Powder 12.6 oz can (357 g) 1740 87 6 cans per case B4161 0087-123901036721 Pregestimil® Powder 1 lb can 2143301 Pregestimil RTU, 20 Cal 2 fl oz bottle 40 2 48 bottles per case B4161 0087-143341143401 Pregestimil RTU, 24 Cal 2 fl oz bottle 48 2 48 bottles per case B4161 0087-143441

*LGG is a registered trademark of Valio Ltd.

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Product Yield/Calories/Unit Unit (fl oz) Case HCPCS Code NDC #

1860 93 6 cans per case B4158 0087-0201423460 173 4 cans per case B4158 0087-020159640 32 6 cans per case B4158 0087-02037340 2 48 bottles per case B4158 0087-145341

1800 82 6 cans per case B4160 0087-00194444 2 48 bottles per case B4160 0087-139041

700 32 6 cans per case B4160 0087-1287411720 86 6 cans per case B4158 0087-8693423440 172 4 cans per case B4158 0087-869343

40 2 48 bottles per case B4158 0087-1464-4140 2 48 bottles per case B4160 0087-13944148 2 48 bottles per case B4160 0087-13914140 2 48 bottles per case B4160 0087-13924148 2 48 bottles per case B4160 0087-13934148 2 48 bottles per case B4158 0087-138841

520 26 12 cans per case B4158 0087-1367411800 90 6 cans per case B4158 0087-1365423340 167 6 cans per case B4158 0087-1365414660 233 4 boxes per carton B4158 0087-136551640 32 4 cartons per case B4158 0087-145941640 32 6 cans per case B4158 0087-145942240 12 8 cartons per case B4158 0087-136641120 6 24 bottles per case B4158 0087-145841

1410 70 6 cartons per case B4158 0087-136545520 26 12 cans per case B4159 0087-119541640 32 4 cartons per case B4159 0087-030951640 32 6 cans per case B4159 0087-030974

1840 92 6 cans per case B4159 0087-1214413640 182 6 cans per case B4159 0087-121442

40 2 48 bottles per case B4159 0087-144941120 6 24 bottles per case B4159 0087-026124

1800 90 6 cans per case 0087-020163240 8 24 cans per case B4160 0087-128941520 26 12 cans per case B4161 0087-049801640 32 6 cans per case B4161 0087-04990140 2 48 bottles per case B4161 0087-143741

120 6 24 bottles per case B4161 0087-0263241960 98 4 cans per case B4161 0087-1200491740 87 6 cans per case B4161 0087-1239012240 112 6 cans per case B4161 0087-036701

40 2 48 bottles per case B4161 0087-14334148 2 48 bottles per case B4161 0087-143441

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Item # Product Description Unit Size Calories/Unit Unit (fl oz) Case HCPCS Code NDC #

TODDLER / CHILDREN’S NUTRITIONALS

140112 Enfagrow™ PREMIUM™ NEXT STEP® Powder 24 oz can 3420 171 6 cans per case B4158 0087-140151128801 Enfagrow PREMIUM NEXT STEP RTU 32 fl oz can 640 32 6 cans per case B4158 0087-128841146102 Enfagrow™ Gentlease® NEXT STEP® Powder 24 oz can 3380 169 4 cans per case 0087-146142140904 Enfagrow™ Soy NEXT STEP® Powder 24 oz can 3220 161 6 cans per case B4159 0087-140944146802 Enfagrow™ PREMIUM™ Toddler Chocolate Powder 24 oz can 2850 134 4 cans per case 0087-1468-42869207 Enfagrow™ PREMIUM™ Toddler Vanilla Powder 24 oz can 3170 132 4 cans per case 0087-8692-47

PRODUCTS FOR SPECIAL MEDICAL NEEDS

128901 Enfaport® RTU, 30 Cal 8 fl oz can 240 8 24 cans per case B4160 0087-128941038721 Portagen® Powder 1 lb can 2100 70 6 cans per case B4158 0087-038701042521 3232 A™ Powder 1 lb can 2270 Varies 6 cans per case B4161 0087-042541

METABOLIC / DIET MODIFIERS

406002 BCAD™ 1 Powder 1 lb can 2270 Varies 6 cans per case B4162 0087-406042008301 BCAD™ 2 Powder 1 lb can 1860 Varies 6 cans per case B4162 0087-008341019801 GA™ Powder 1 lb can 2270 Varies 6 cans per case B4162 0087-019841009501 HCY™ 1 Powder 1 lb can 2270 Varies 6 cans per case B4162 0087-009541019901 HCY™ 2 Powder 1 lb can 1860 Varies 6 cans per case B4157 or B4162 0087-019941007801 LMD™ Powder 1 lb can 2270 Varies 6 cans per case B4157 or B4162 0087-007841008501 OA™ 1 Powder 1 lb can 2270 Varies 6 cans per case B4162 0087-008541019101 OA™ 2 Powder 1 lb can 1860 Varies 6 cans per case B4157 or B4162 0087-019141099401 PFD™ 1 Powder 1 lb can 2410 Varies 6 cans per case B4155 0087-099441007901 PFD™ 2 Powder 1 lb can 1820 Varies 6 cans per case B4155 0087-007941007407 Phenyl-Free® 1 Powder 1 lb can 2270 Varies 6 cans per case B4162 0087-007447008001 Phenyl-Free® 2 Powder 1 lb can 1860 Varies 6 cans per case B4162 0087-008041008101 Phenyl-Free® 2 HP Powder 1 lb can 1770 Varies 6 cans per case B4157 or B4162 0087-008141019401 TYROS™ 1 Powder 1 lb can 2008201 TYROS™ 2 Powder 1 lb can 1860 Varies 6 cans per case B4162 0087-008241009201 WND® 1 Powder 1 lb can 2009301 WND® 2 Powder 1 lb can 1860 Varies 6 cans per case B4157 or B4162 0087-009341

HUMAN MILK FORTIFIER

201418 Enfamil® Human Milk Fortifier Powder 0.71 g Foil Sachet 3.5 N/A 200 units per case B4155 0087-201448

WATERS

134601 5% Glucose Water RTU 2 fl oz bottle 10 2 48 bottles per case N/A 0087-134641134501 Water RTU 2 fl oz bottle 0 2 48 bottles per case N/A 0087-134541

ORAL ELECTROLYTE SOLUTION

026506 Enfamil® Enfalyte® RTU 6 fl oz bottle 22 6 24 bottles per case N/A 0087-026524

ACCESSORIES

Please refer to page 83.

HOSPITAL GIFTS

Please refer to page 86.

DIETARY SUPPLEMENTS

869502 Expecta® LIPIL® DHA Supplement Capsule 10-count blister packs (3 per carton) N/A N/A 12 cartons per case N/A 0087-869542086604 Enfamil® D-VI-Sol™ Drops With Dropper 50 mL N/A N/A 12 bottles per case N/A 0087-086644074026 Enfamil® Fer-In-Sol® Drops With Dropper 50 mL N/A N/A 12 bottles per case N/A 0087-074002040265 Enfamil® Poly-Vi-Sol® Drops With Dropper 50 mL N/A N/A 12 bottles per case N/A 0087-040203040506 Enfamil® Poly-Vi-Sol® with Iron Drops With Dropper 50 mL N/A N/A 12 bottles per case N/A 0087-040501040365 Enfamil® Tri-Vi-Sol® Drops With Dropper 50 mL N/A N/A 12 bottles per case N/A 0087-040303045329 Enfamil® Tri-Vi-Sol® with Iron Drops With Dropper 50 mL N/A N/A 12 bottles per case N/A 0087-045303

N/A=Not Available

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Product Yield/Calories/Unit Unit (fl oz) Case HCPCS Code NDC #

3420 171 6 cans per case B4158 0087-140151640 32 6 cans per case B4158 0087-128841

3380 169 4 cans per case 0087-1461423220 161 6 cans per case B4159 0087-1409442850 134 4 cans per case 0087-1468-423170 132 4 cans per case 0087-8692-47

240 8 24 cans per case B4160 0087-1289412100 70 6 cans per case B4158 0087-0387012270 Varies 6 cans per case B4161 0087-042541

2270 Varies 6 cans per case B4162 0087-4060421860 Varies 6 cans per case B4162 0087-0083412270 Varies 6 cans per case B4162 0087-0198412270 Varies 6 cans per case B4162 0087-0095411860 Varies 6 cans per case B4157 or B4162 0087-0199412270 Varies 6 cans per case B4157 or B4162 0087-0078412270 Varies 6 cans per case B4162 0087-0085411860 Varies 6 cans per case B4157 or B4162 0087-0191412410 Varies 6 cans per case B4155 0087-0994411820 Varies 6 cans per case B4155 0087-0079412270 Varies 6 cans per case B4162 0087-0074471860 Varies 6 cans per case B4162 0087-0080411770 Varies 6 cans per case B4157 or B4162 0087-0081412270 Varies 6 cans per case B4162 0087-0194411860 Varies 6 cans per case B4162 0087-0082412270 Varies 6 cans per case B4157 or B4162 0087-0092411860 Varies 6 cans per case B4157 or B4162 0087-009341

3.5 N/A 200 units per case B4155 0087-201448

10 2 48 bottles per case N/A 0087-1346410 2 48 bottles per case N/A 0087-134541

22 6 24 bottles per case N/A 0087-026524

N/A N/A 12 cartons per case N/A 0087-869542N/A N/A 12 bottles per case N/A 0087-086644N/A N/A 12 bottles per case N/A 0087-074002N/A N/A 12 bottles per case N/A 0087-040203N/A N/A 12 bottles per case N/A 0087-040501N/A N/A 12 bottles per case N/A 0087-040303N/A N/A 12 bottles per case N/A 0087-045303


FORMULA DILUTION INSTRUCTIONS*

FROM POWDER†

*Note: Powdered products are not commercially sterile and should not be used forimmunocompromised patients, unless clinically required, and then only under strictmedical supervision of preparation and use.

†These dilutions can be used with the following Mead Johnson powder formulas:

ENFAMIL A.R.®, ENFAMIL® RESTFULL™

Per 1 ScoopCalories desired Add 1 scoop powder Formula yield,

per fl oz‡ per mL to water (fl oz) fl oz 20 0.68 2.0 2.222 0.74 1.8 2.024 0.81 1.6 1.8

Enfamil A.R. and Enfamil RestFull should not be diluted to caloric concentrations higherthan 24 Calories/fluid ounce because of increased viscosity.

Enfamil A.R. and Enfamil RestFull formulas should be measured with unpacked, levelscoops.

Powders mix best when added on top of water. Then close the bottle and shake forabout 5 seconds. The number of scoops and the amount of water to add can bedoubled or tripled to make a larger volume.

One scoop of powder provides 44 Calories.

One fl oz = 29.57 mL.

‡Fluid ounce measures in the above table are rounded to the nearest 0.1 fl oz.

ENFAMIL® PREMIUM™, ENFAGROW™ PREMIUM™ NEXT STEP®, ENFAMIL® PROSOBEE®, ENFAGROW™ GENTLEASE® NEXT STEP®

Per 1 ScoopCalories desired fl oz of water to Formula yield,

per fl oz‡ per mL add to 1 scoop fl oz 20 0.68 2.0 2.222 0.74 1.8 2.024 0.81 1.6 1.926 0.88 1.5 1.727 0.91 1.4 1.628 0.95 1.4 1.630 1.01 1.3 1.5

Enfamil PREMIUM, Enfagrow PREMIUM NEXT STEP, Enfamil ProSobee, and EnfagrowGentlease NEXT STEP should be measured with unpacked, level scoops.


One scoop of Enfamil PREMIUM and Enfagrow PREMIUM NEXT STEP powder provides44 Calories. One scoop of Enfamil ProSobee and Enfagrow Gentlease NEXT STEPprovides 45 calories.



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ENFAGROW™ SOY NEXT STEP®



Enfagrow Soy NEXT STEP should be measured with unpacked, level scoops.





NUTRAMIGEN® WITH ENFLORA™ LGG®§



Nutramigen with Enflora LGG powder should be measured with packed, level scoops.




One-half fl oz of water = 1 tablespoon.


§LGG is a registered trademark of Valio Ltd.

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NUTRAMIGEN® AA™



Nutramigen AA powder should be measured with unpacked, level scoops.






PREGESTIMIL®



Pregestimil powder should be measured with packed, level scoops.






218

ENFAMIL® GENTLEASE®



Enfamil Gentlease should be measured with unpacked, level scoops.






ENFAMIL® ENFACARE® POWDER



Enfamil EnfaCare powder should be measured with unpacked, level scoops.

Powder mixes best when added on top of water. Then close the bottle and shake forabout 5 seconds. The number of scoops and the amount of water to add can bedoubled or tripled to make a larger volume.

One unpacked, level scoop of Enfamil EnfaCare powder (9.8 g) provides 48 Calories.



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GRAM WEIGHTS FOR SCOOPS AND CUPS, CALORIES PER GRAM, ANDWATER DISPLACED BY 1 G POWDER

Scoop Measuring Calories/ Water (mL)(grams) cup (grams) gram displaced by

1 g powder

Enfamil® PREMIUM™ 8.8 113§ 5.0 0.76Enfamil® EnfaCare® 9.8 114§ 4.9 0.76Enfamil A.R.® 8.8 97 5.0 0.73Enfamil® Gentlease® 8.7 111§ 5.1 0.77Enfagrow™ PREMIUM™ NEXT STEP® 8.8 95§ 5.1 0.76Enfagrow™ Soy NEXT STEP® 9.3 101§ 4.8 0.71Enfagrow™ PREMIUM™ Toddler Chocolate 9 133 4.2 0.69Enfagrow™ PREMIUM™ Toddler Vanilla 9 108 4.7 0.72Nutramigen® 9.0|| 129|| 5.0 0.76Portagen® 9.4|| 122|| 4.7 0.66Pregestimil® 8.9|| 128|| 5.0 0.79Enfamil® ProSobee® 8.9 NA 5.0 0.77Enfamil® RestFull™ 8.8 97 5.0 0.73Enfamil® Human Milk Fortifier 4.9Enfagrow™ Gentlease® NEXT STEP® 9 108 5.0 0.763232 A™ No Scoop 162§,|| 5.0¶ N/ABCAD™ 1 4.5 117 5.0 0.76BCAD™ 2 16.8|| 165|| 4.1 0.68GA™ 4.5 109 5.0 0.76HCY™ 1 4.5 116 5.0 0.76HCY™ 2 17.3|| 139 4.1 0.67LMD™ 4.5 116 5.0 0.76OA™ 1 4.5 117 5.0 0.76OA™ 2 16|| 132 4.1 0.68PFD™ 1 4.5 108 5.3 0.79PFD™ 2 15.6|| 149|| 4.0 0.66Phenyl-Free® 1 4.5 127|| 5.0 0.76Phenyl-Free® 2 17.6|| 169|| 4.1 0.68Phenyl-Free® 2 HP 16.3|| 169|| 3.9 0.66TYROS™ 1 4.5 113 5.0 0.76TYROS™ 2 17|| 156|| 4.1 0.68WND® 1 4.5 111 5.0 0.75WND® 2 17.1|| 140 4.1 0.69Nutramigen® with Enflora™ LGG® 9|| 97|| 5.0 0.72Nutramigen® AA™ 4.5 115 5.1 0.76

§Values derived from grams/qt or other values.||Packed level measure. All others are unpacked level measures.¶Powder only (not prepared with added ingredients).N/A=Not Available

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FROM CONCENTRATE**These dilutions can be used with the following Mead Johnson concentrate formulas:

ENFAMIL® PREMIUM™, NUTRAMIGEN®, AND ENFAMIL® PROSOBEE®

Fl oz of water† toCalories desired add to 13 fl oz can Formula yield,

per fl oz‡ of concentrated liquid fl oz20 13 2622 10.5 23.524 8.5 21.526 7 2027 6 1928 5.5 18.530 4.5 17.5

One can of concentrated liquid provides 520 Calories.One fl oz of undiluted concentrated liquid provides 40 Calories.One-half fl oz of water = 1 tablespoon.†When accuracy is essential, mL measures should be used. Fluid ounce measures areprovided for convenience when larger variance in prepared dilution is acceptable.

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NURSETTE® BOTTLE OR BREAST MILK PREPARATION20–30 Calories per fl oz General guidelines are provided as a convenience, based on calculated results ofmixing; not clinically tested. Approximate household measurements are provided as aconvenience when a precise dilution is not required. If necessary, check calories/g anddisplacement for powder selected (see previous page). Undiluted concentrated liquidformulas provide 1.35 Calories/mL.

The choices of caloric level and appropriate additions to infant formula or breast milk for a particular infant are clinical judgments best made by the dietitian or doctor mostfamiliar with the baby’s medical history and nutritional needs. When choosing anappropriate addition, consider the effect on nutrient composition and osmolality. Make changes gradually to decrease risk of intolerance.

Starting with 20 Calories/fl oz, 2 fl oz (Formula or breast milk)Choose one additive:

Goal, Powder* ConcentratedCalories/fl oz formula liquid formula

22 0.9 g (~1⁄4 tsp) 7 mL (~11⁄2 tsp) 24 1.8 g (~1⁄2 tsp) 15 mL (~1 Tbsp) 27 3.2 g (~11⁄2 tsp) 32 mL (~2 Tbsp)

Starting with 22 Calories/fl oz, 2 fl oz FormulaChoose one additive:

Goal, Powder* ConcentratedCalories/fl oz Water formula liquid formula

20 6 mL (~1 tsp) — — 24 — 0.9 g (~1⁄2 tsp) 7 mL (~11⁄2 tsp) 27 — 2.3 g (~1 tsp) 23 mL (~1 Tbsp + 11⁄2 tsp)

Starting with 24 Calories/fl oz, 2 fl oz (Formula or fortified breast milk)Choose one additive:

Goal, Powder‡ ConcentratedCalories/fl oz Water formula liquid formula

20 12 mL (~21⁄2 tsp) — —22 5 mL (~1 tsp) — —27 — 1.3 g (~1⁄2 tsp) 14 mL (~ 1 Tbsp)30 — 2.7 g (~1 tsp) 35 mL (~2 Tbsp + 1 tsp)

*Note: Powdered products are not commercially sterile and should not be used forimmunocompromised patients, unless clinically required, and then only under strictmedical supervision of preparation and use.

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POWDER CAN YIELD BY MEASURECan Yield

Label Product Can Size Scoops Declaration* Calories†

Enfamil® EnfaCare® 12.8 oz (363 g) 37 82 fl oz 1800Enfamil A.R.® 12.9 oz (366 g) 41 93 fl oz 1860Enfamil® PREMIUM™ 12.5 oz (354 g) 40 90 fl oz 1800

23.4 oz (663 g) 75 167 fl oz 3340Enfamil® Gentlease® 12 oz (340 g) 39 86 fl oz 1720

24 oz (680 g) 78 172 fl oz 3440Enfagrow™ PREMIUM™

NEXT STEP® 24 oz (680 g) 77 171 fl oz 3420Enfagrow™ Soy

NEXT STEP® 24 oz (680 g) 73 161 fl oz 3220Enfagrow™ PREMIUM™

Toddler Chocolate 24 oz (680 g) 75 134 fl oz 2850Enfagrow™ PREMIUM™

Toddler Vanilla 24 oz (680 g) 75 132 fl oz 3170Nutramigen® 16 oz (454 g) 50 113 fl oz 2260Pregestimil® 16 oz (454 g) 51 112 fl oz 2240Enfamil® ProSobee® 12.9 oz (366 g) 41 92 fl oz 1840

25.7 oz (729 g) 81 183 fl oz 3660Enfamil® RestFull™ 12.5 oz (354 g) 40 90 fl oz 1800Enfagrow™ Gentlease®

NEXT STEP® 24 oz (680 g) 75 169 fl oz 3380Nutramigen® with

Enflora™ LGG® 19.8 oz (561 g) 62 139 fl oz 2780Nutramigen® AA™ 14.1 oz (400 g) 88 98 fl oz 1960

*Prepared label directions.†Calculated from fl oz as stated on label.

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APPROXIMATE CONVERSION TABLES

Popular MeasuresU.S. Measures Metric

1 teaspoon 5 mL1 tablespoon (1/2 fl oz) 15 mL1 cup (8 fl oz) 237 mL1 pint (16 fl oz) 473 mL1 quart (32 fl oz) 946 mL

Avoirdupois

U.S. Measures Metric

1 oz 28.35 g1 Ib 453.6 g2.2 Ib 1000 g

(1 kilogram)To convert: Pounds to grams, multiply by 453.6

Grams to pounds, divide by 453.6

Liquid Measures

Metric Apothecary

1000 mL 1.06 quart946 mL 1 quart500 mL 1.06 pint473 mL 1 pint100 mL 3.38 fl oz29.57 mL 1 fl oz

To convert: Milliliters to fl oz, divide by 29.57Fl oz to milliliters, multiply by 29.57

Temperatures

Centigrade Fahrenheit

0° Water freezes 32°22 Room temperature 7237 Body temperature 98.6

100 Water boils 212121 Autoclave temperature 250

To convert: Centigrade to Fahrenheit: 1. Multiply by 92. Divide by 53. Add 32

Fahrenheit to Centigrade: 1. Subtract 322. Multiply by 53. Divide by 9

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CALORIC DISTRIBUTION TABLECaloric distribution

(% of calories)Protein Fat Carbohydrate

BCAD™ 1* 13 47 40BCAD™ 2* 24 19 57Enfamil® EnfaCare® 11 47 42Enfamil® Enfalyte® 0 0 100Enfamil A.R.® 10 46 44Enfamil® Human Milk Fortifier 32 62 6Enfamil® PREMIUM™ 20 8.5 48 43.5Enfamil® PREMIUM™ 24 8.5 48 43.5Enfamil® Premature 20 12 44 44Enfamil® Premature 24 12 44 44GA™* 12 47 41Enfamil® Gentlease® 9 48 43HCY™ 1* 13 47 40HCY™ 2* 22 19 59LMD™* 13 47 40Enfagrow™ PREMIUM™ NEXT STEP® 10 48 42Enfagrow™ Soy NEXT STEP® 13 40 47Nutramigen® 11 48 41OA™ 1* 12 47 41OA™ 2* 21 20 59PFD™ 1* 0 54 46PFD™ 2* 0 11 89Phenyl-Free® 1* 13 47 40Phenyl-Free® 2* 22 19 59Phenyl-Free® 2 HP* 41 14 45Portagen® 14 40 46Pregestimil® 20 11 48 41Pregestimil® 24 11 48 413232 A™ (made with 81 g powder

and 59 g added carbohydrate) 11 35 543232 A (without carbohydrate) 18 55 27Enfamil® ProSobee® 10 48 42Enfamil® RestFull™ 10 46 44TYROS™ 1* 13 47 40TYROS™ 2* 22 19 59WND® 1* 5 47 48WND® 2* 8 23 69Enfagrow™ PREMIUM™ Toddler Chocolate 15 28 57Enfagrow™ PREMIUM™ Toddler Vanilla 16 43 41Enfagrow™ Gentlease® NEXT STEP® 10 48 42Nutramigen® with Enflora™ LGG® 11 48 41Nutramigen® AA™ 11 48 41Enfaport® 14 45 41

*Protein is incomplete, since one or more of the amino acids is missing or provided atvery low levels. Protein is comprised of amino acids, and the amounts are calculated asnitrogen (g) x 6.25 g of protein/g of nitrogen.

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KOSHER PRODUCTSKosher-certified products will have a “U” within a circle in the product label.

The following Mead Johnson Nutrition products are manufactured under thesupervision of the Kashruth Division of the Union of Orthodox JewishCongregations of America, and are kosher and pareve when bearing the O.U.symbol of certification on the label, and are kosher and contain dairy ingredientswhen bearing the O.U.D. symbol of certification on the label.Product Kosher DesignationEnfamil A.R.® O.U.D.Enfamil® EnfaCare® O.U.D.Enfamil® Enfalyte® O.U.D. Pareve*Enfamil® Gentlease® O.U.D.Enfamil® Human Milk Fortifier O.U.D.Enfamil® PREMIUM™ O.U.D.Enfagrow™ PREMIUM™ NEXT STEP® O.U.D.Enfagrow™ Soy NEXT STEP® O.U. PareveNutramigen® Not kosher†

Pregestimil® Not kosher†

Enfamil® Premature O.U.D.Enfamil® ProSobee® (powders) O.U. PareveEnfamil ProSobee (liquids) O.U. Pareve* Enfamil® RestFull™ O.U.D. Enfamil® D-Vi-Sol™ Drops O.U.Enfamil® Fer-In-Sol® Drops O.U. Enfamil® Poly-Vi-Sol® Drops O.U. Enfamil® Poly-Vi-Sol® with Iron Drops O.U. Portagen® O.U.D. Enfamil® Tri-Vi-Sol® Drops O.U. Enfamil® Tri-Vi-Sol® with Iron Drops O.U.

*Pareve ingredients: manufactured on dairy equipment.†The casein is enzymatically hydrolyzed (broken down) using a pork pancreatic enzyme.An insignificant percentage of the enzyme is present in the prepared formulas. IfNutramigen or Pregestimil is medically necessary for the baby, some rabbis provideexceptions for use of the product.

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OSMOLALITY/OSMOLARITY TABLEFormula Calories/ Osmolality Osmolarity

fl oz mOsm/kg water mOsm/LEnfamil® EnfaCare® Powder 22 310 270Enfamil® EnfaCare® RTU 22 250 220Enfamil® Enfalyte® ~3.5 170 167Enfamil A.R.® Powder 20 230 210Enfamil A.R.® RTU 20 240 220Enfamil® Human Milk 14 Cal/Fortifier 4 packets +35* N/AEnfamil® PREMIUM™ 20 20 300 270Enfamil PREMIUM™ 24 24 360 320Enfamil® Premature 20 20 240 220Enfamil® Premature 24 24 300 260Enfamil® Gentlease® Powder 20 230 210Enfamil® Gentlease® RTU 20 220 200Enfagrow™ PREMIUM™ NEXT STEP® 20 270 240Enfagrow™ Soy NEXT STEP® 20 230 200Nutramigen® Powder 20 300 270Nutramigen® RTU 2 fl oz 20 320 290Nutramigen® Other RTUs 20 260 230Portagen® 30 350 300Pregestimil® Powder 20 320 280Pregestimil® 20 RTU 20 290 260Pregestimil® 24 RTU 24 340 300Enfamil® ProSobee® Powder 20 180 162Enfamil® ProSobee® RTU 20 170 153Enfamil® RestFull™ 20 230 210Enfagrow™ Gentlease® NEXT STEP® 20 230 210Enfagrow™ PREMIUM™ Toddler Chocolate 21 N/A N/AEnfagrow™ PREMIUM™ Toddler Vanilla 24 N/A N/ANutramigen® with Enflora™ LGG® 20 300 270Nutramigen® AA™ 20 350 320Enfaport® 30 280 240

Osmolalities for formulas are Mead Johnson analytical values.Osmolarity is calculated from osmolality data.*Value for Enfamil HMF reflects the increase in osmolality when 4 packets of fortifier areadded to 100 mL of preterm breast milk.

N/A=Not Available

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POTENTIAL RENAL SOLUTE LOAD1 TABLECalories/ mOsm/ mOsm/

fl oz 100 Calories 100 mLEnfamil® EnfaCare® Liquid 22 25 18.3Enfamil® EnfaCare® Powder 22 25 18.4Enfamil® Enfalyte® ~3.5 96 12Enfamil A.R.® 20 23 15.3Enfamil® Human 14 70 9.8

Milk Fortifier (per 4 (per 100 Calories (per 4 packets) of EHMF) packets)

Enfamil® PREMIUM™ 20 (Liq) 20 19.1 13Enfamil® PREMIUM™ 20 (Pwd) 20 19.1 12.9Enfamil® PREMIUM™ 24 24 18.9 15.3Enfamil® Premature 20 20 27 18.4Enfamil® Premature 24 24 27 22Enfamil® Gentlease® 20 21 14Enfagrow™ PREMIUM™ NEXT STEP® 20 26 17.7Enfagrow™ Soy NEXT STEP® 20 30 20Nutramigen® 20 25 16.8Portagen® 30 30 30Pregestimil® 20 20 25 16.8Pregestimil® 24 RTU 24 25 203232 A™ with Carbohydrate 20 25 16.93232 A™ w/o Carbohydrate 12.7 40 16.9Enfamil® ProSobee® 20 23 15.6Enfamil® RestFull™ 20 23 15.3Enfagrow™ Gentlease® NEXT STEP® 20 26 17.8Enfagrow™ PREMIUM™ Toddler Chocolate 21 37 26Enfagrow™ PREMIUM™ Toddler Vanilla 24 36 29Nutramigen® with Enflora™ LGG® 20 25 16.8Nutramigen® AA™ 20 25 16.8Enfaport® 30 28 29


POTENTIAL RENAL SOLUTE LOAD1 TABLE METABOLICINFANT/TODDLER FORMULAS

mOsm/100 g powderBCAD™ 1 147 GA™ 140 HCY™ 1 144 LMD™ 145 OA™ 1 142 PFD™ 1 62 Phenyl-Free® 1 144 TYROS™ 1 148 WND® 1 88


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HOSPITAL OR INSTITUTIONAL STORAGE GUIDELINESFOR PREPARED FORMULA

RecommendationRefrigeration • Dedicated refrigerators recommended

• Store at 35–40°F (2–4°C) no longer than 24 hoursRoom Temperature • Hold no longer than a total of 2 hours before feeding

• If bottle is warmed, discard after 1 hourAfter Feeding Begins • Feed within 1 hour or discard

• Do not refrigerate for later feedings

TUBE FEEDING HANG TIMES*,†

Neonates or Infants and ChildrenImmunocompromised with Healthy

Infants/Children Immune SystemsReady-To-Use liquid 4 hours 8 hours

unaltered infant formula (commercially sterile)

Concentrated liquid formulas (commercially sterile) 4 hours 4 hours

Powdered formulas (not sterile)Powder added to liquid formula 4 hours 4 hours

or expressed breast milk2

Failure to follow these instructions could result in severe harm.*Adapted from: Infant Feedings: Guidelines for Preparation of Formula and Breastmilk inHealth Care Facilities. American Dietetic Association. 2004:91.

†For reservoir and tube-change guidelines, refer to: Guidelines for Preparation ofFormula and Breastmilk in Health Care Facilities. American Dietetic Association. 2004.

2. Telang S, Berseth CL, Ferguson PW, Kinder JM, DeRoin M, Petschow BW. Fortifyingfresh human milk with commercial powdered human milk fortifiers does not affectbacterial growth during 6 hours at room temperature. J Am Diet Assoc.2005;105:1567-1572.

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230

INFANT FORMULA AMINO ACID COMPOSITIONSEssential Amino Acids

Histidine Isoleucine Leucine Lysine


mg/100 Calories 78 160 330 260mg/100 g* 390 790 1640 1280

Enfamil A.R.®

mg/100 Calories 70 125 250 200mg/100 g* 350 620 1250 1000


mg/100 Calories 42 130 220 149mg/100 g* 210 660 1120 750

Enfamil® Premature mg/100 Calories 60 186 320 210


mg/100 Calories 46 143 240 163mg/100 g* 240 730 1250 840

Enfagrow™ PREMIUM™ NEXT STEP®

mg/100 Calories 73 130 260 210mg/100 g* 370 660 1320 1060


mg/100 Calories 89 162 270 210mg/100 g* 420 770 1290 990

Enfagrow™ PREMIUM™ Toddler Vanillamg/100 Calories 109 200 390 320mg/100 g* 50 930 1880 1510

Enfagrow™ PREMIUM™ Toddler Chocolate mg/100 Calories N/A N/A N/A N/Amg/100 g* N/A N/A N/A N/A

Nutramigen®

mg/100 Calories 84 168 290 240mg/100 g* 420 830 1420 1200

Pregestimil®

mg/100 Calories 84 168 290 240mg/100 g* 420 840 1430 1200

3232 A™

mg/100 g* 660 1320 2200 1890


mg/100 Calories 68 123 210 158mg/100 g* 340 610 1030 790

Enfamil® RestFull™mg/100 Calories 70 125 250 200mg/100 g* 350 620 1250 1000

Enfagrow™ Gentlease® NEXT STEP®

mg/100 Calories 52 161 280 185mg/100 g* 260 800 1370 920

Nutramigen® with Enflora™ LGG®

mg/100 Calories 84 168 290 240mg/100 g* 420 830 1420 1200

Nutramigen® AA™

mg/100 Calories 73 190 340 220mg/100 g* 370 970 1760 1140

Enfaport®

mg/100 Calories 110 200 350 300

*Powder only. †Methionine level is 83 mg/100 Cal in powder. N/A=None Added

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Methionine Cystine Phenylalanine Tyrosine Threonine Tryptophan Valine

67 36 151 118 188 59 174330 179 750 580 920 290 860

65 23 123 113 110 34 150320 112 610 560 550 170 740

42 26 84 97 113 32 132210 129 420 490 570 163 670

60 37 120 138 162 46 189

46 28 92 106 124 35 145240 144 470 540 640 182 740

68 23 127 117 114 36 156340 118 640 590 580 179 790

69 36 175 129 122 43 168330 173 830 610 580 200 800

101 35 191 176 172 53 230480 167 910 840 820 250 1120

N/A N/A N/A N/A N/A N/A N/AN/A N/A N/A N/A N/A N/A N/A

87 45 134 62 137 45 210430 220 670 310 680 220 1040

87 45 134 62 137 45 210430 220 670 310 690 220 1050

680 350 1060 620 1080 350 1650

50† 28 133 98 93 33 128410 138 660 490 460 163 640

65 23 123 113 110 34 150320 112 610 560 550 170 740

52 32 104 120 140 40 164260 157 520 590 700 200 810

87 45 134 62 137 45 210430 220 670 310 680 220 1040

64 73 140 151 171 67 210330 370 720 770 870 340 1090

100 10.3 192 200 144 45 250

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INFANT FORMULA AMINO ACID COMPOSITIONSNonessential Amino Acids

*Powder only. N/A=None Added

Arginine Alanine AsparticAcid GlutamicAcid


mg/100 Calories 101 140 330 670mg/100 g* 500 690 1610 3300

Enfamil A.R.®

mg/100 Calories 78 85 200 530mg/100 g* 380 420 970 2600


mg/100 Calories 48 90 200 410mg/100 g* 240 460 990 2000

Enfamil® Premature mg/100 Calories 69 129 280 580


mg/100 Calories 53 99 210 440mg/100 g* 270 510 1100 2300

Enfagrow™ PREMIUM™ NEXT STEP®

mg/100 Calories 81 88 200 550mg/100 g* 410 450 1020 2800


mg/100 Calories 260 142 390 620mg/100 g* 1260 680 1840 3000

Enfagrow™ PREMIUM™ Toddler Vanillamg/100 Calories 121 133 300 820mg/100 g* 580 630 1450 3900

Enfagrow™ PREMIUM™ Toddler Chocolatemg/100 Calories N/A N/A N/A N/Amg/100 g* N/A N/A N/A N/A

Nutramigen®

mg/100 Calories 112 101 220 640mg/100 g* 560 500 1110 3200

Pregestimil®

mg/100 Calories 112 101 220 640mg/100 g* 560 500 1120 3200

3232 A™

mg/100 g* 880 790 1760 5100


mg/100 Calories 200 108 290 470mg/100 g* 1020 550 1500 2400

Enfamil® RestFull™mg/100 Calories 78 85 200 530mg/100 g* 380 420 970 2600

Enfagrow™ Gentlease® NEXT STEP®

mg/100 Calories 60 112 240 500mg/100 g* 300 550 1200 2500

Nutramigen® with Enflora™ LGG®

mg/100 Calories 112 101 220 640mg/100 g* 560 500 1110 3200

Nutramigen® AA™

mg/100 Calories 148 270 560 168mg/100 g* 760 1390 2900 860

Enfaport®

mg/100 Calories 141 130 260 820

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Glycine Proline Serine

67 270 176330 1340 870

48 240 138240 1170 680

42 179 103210 900 520

60 260 147

46 200 113240 1000 580

49 240 143250 1230 720

139 178 168660 850 800

74 370 210350 1750 1020

N/A N/A N/AN/A N/A N/A

67 300 176330 1500 880

67 300 176340 1510 880

530 2400 1390

105 135 128540 690 650

48 240 138240 1170 680

52 220 127260 1100 630

67 300 176330 1500 880

73 280 171370 1430 870

69 410 175

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METABOLIC FORMULA AMINO ACID COMPOSITIONSEssential Amino Acids (mg per 100 g powder)

Histidine Isoleucine Leucine Lysine

BCAD™ 1 550 0 0 1770BCAD™ 2 890 0 0 2900GA™ 420 1210 2200 0HCY™ 1 410 1150 2100 1310HCY™ 2 550 1560 2900 1780LMD™ 470 580 0 1510OA™ 1 470 0 2400 1510OA™ 2 650 0 3400 2100PFD™ 1 0 0 0 0PFD™ 2 0 0 0 0Phenyl-Free® 1 410 1150 2100 1300Phenyl-Free® 2 550 1560 2900 1760Phenyl-Free® 2 HP 1000 2800 5200 3200TYROS™ 1 420 1200 2200 1370TYROS™ 2 550 1580 2900 1800WND® 1 440 990 2000 1240WND® 2 550 1250 2500 1570Portagen® 520 940 1650 1410

Nonessential Amino Acids (mg per 100 g powder)

Arginine Alanine AsparticAcid GlutamicAcid

BCAD 1 1180 1280 1560 3100BCAD 2 1730 1870 2300 4500GA 1040 3600 1360 0HCY 1 990 1070 1300 2600HCY 2 1340 1450 1760 3500LMD 1100 4900 1430 0OA 1 1000 4600 1320 0OA 2 1340 6100 1760 0PFD 1 0 0 0 0PFD 2 0 0 0 0Phenyl-Free 1 970 1070 1280 2600Phenyl-Free 2 1320 1450 1740 3500Phenyl-Free 2 HP 2400 2600 3200 6300TYROS 1 1100 1200 1450 2900TYROS 2 1450 1580 1910 3800WND 1 0 0 0 0WND 2 0 0 0 0Portagen 660 610 1250 3900

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Methionine Cystine Phenylalanine Tyrosine Threonine Tryptophan Valine

470 340 920 920 760 410 0770 550 1490 1490 1220 650 0360 260 710 710 790 0 1310

0 600 680 680 760 310 12600 810 920 920 1030 420 1720

410 290 780 780 870 340 6300 290 790 790 0 350 00 420 1110 1110 0 480 00 0 0 0 0 0 00 0 0 0 0 0 0

360 240 0 1600 750 290 1250480 330 0 2200 1010 400 1690880 600 0 4000 1840 720 3100370 270 0 0 780 320 1320480 350 0 0 1030 420 1740250 200 670 800 850 390 990310 250 840 1010 1070 490 1250470 49 910 940 680 210 1180

Glycine Proline Serine

710 1560 7801030 2300 11301040 1360 710580 1300 650790 1760 880

1100 1430 7501000 1320 6901340 1760 920

0 0 00 0 0

580 1280 630790 1740 860

1440 3200 1560650 1450 720860 1910 950

0 0 00 0 0

320 1930 830

LB6 REV 3/10 ©2010 Mead Johnson & Company, LLC

The Enfamil®

Infant Feeding PyramidMakes it easy to find formula solutions to common feeding issues.

For more information, contact your sales professional, call 1.800.BABY123 or visit enfamilprofessional.com

‡LGG is a registered trademark of Valio Ltd.

†Due to cow’s milk protein allergy.Enfamil RestFull and Enfamil A.R. are the same formulation,packaged differently for different concerns.

*Studied before theaddition of prebiotics

Enfamil® PREMIUM™ Enfamil® RestFull™ Enfamil A.R.® Enfamil® Gentlease® Nutramigen®

with Enflora™ LGG®‡

Normalfeeding

NORMAL FEEDING MILD FEEDING CONCERNS RECOGNIZEDMEDICAL NEED

Nighttime Spit up Fussiness or gas Colic†

mj pediatric products handbook

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