Molecular Biology

• Molecular Biology David Clark

• 分子生物學 導讀本 譯者 王祖興 高立圖書公司

Cells, DNA and protein

A schematic diagram of an animal cell accompanied by electron micrographs of its organelles

eucaryotes v.s procaryotes

Figure 4

A drawing of a plant cell accompanied by electron micrographs of its organelles.

Scale drawings of some prokaryotic cells

A schematic diagram of a prokaryotic cell

The construction of cells

•DNA or RNA (dNTP or NTP)

•Protein (amino acid)

•Carbohydrates ( 單醣 雙醣 多醣 )

•Lipid etc. ( 生物膜 )

The construction of cells

•DNA or RNA

•Protein

•Carbohydrates

•Lipid etc.

Major biological functions of protein

• Catalytic proteins: A+B C

• Structural proteins

• Transport proteins

• Regulatory proteins

• Protective proteins : antibodies

enzyme

central dogma

Figure 3.11

RNA polymerase

σ

α2ββ’ Core enzyme

σ promoter

DNA

α2ββ’ α2ββ’

translation

RBS

RBS: ribosome binding site

Ribosome(r RNA + r protein)

AUGCUUGAAUAA

  模板 單體 產物 酵素 備註

DNA replication

DNA dNTP DNA DNA polymerase

 

transcription DNA NTP RNA RNA polymerase

promoter

translation mRNA 胺基酸 蛋白質 ribosome Ribosome binding site

(RBS)tRNA

 

(ori)

Polycistronic mRNA