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1 Molecular Evolution and Functional Characterization of Lysine/ornithine Decarboxylase Involved in Lycopodium Alkaloid Biosynthesis in Clubmosses Supplemental Data Supplemental Figures, Tables, and Data Files in this Data supplement: Supplemental Data - Supplemental Figures 1-5 Supplemental Data - Supplemental Tables 1-4 Supplemental Data - Supplemental Data S1-2

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Page 1: Molecular Evolution and Functional Characterization of … · Molecular Evolution and Functional Characterization of Lysine/ornithine Decarboxylase Involved in Lycopodium Alkaloid

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Molecular Evolution and Functional Characterization of Lysine/ornithine Decarboxylase

Involved in Lycopodium Alkaloid Biosynthesis in Clubmosses

Supplemental Data

Supplemental Figures, Tables, and Data

Files in this Data supplement:

Supplemental Data - Supplemental Figures 1-5

Supplemental Data - Supplemental Tables 1-4

Supplemental Data - Supplemental Data S1-2

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112

Page 3: Molecular Evolution and Functional Characterization of … · Molecular Evolution and Functional Characterization of Lysine/ornithine Decarboxylase Involved in Lycopodium Alkaloid

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Supplemental Figure S1. Alignment of selected eukaryotics ODCs and L/ODCs amino acid

sequences. Filled black stars indicate amino acid residues which are involved in catalytic site. Black

arrow heads indicate the amino acids at position 112 and 344 (LaL/ODC numbering). The underlined

amino acid sequences indicate the position of degenerate primers designed for LclL/ODC, HsL/ODC,

and TlL/ODC cloning.

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Supplemental Figure S2. SDS-PAGE of the recombinant LcL/ODC, NtODC3, and their mutant

proteins purified from E. coli. Proteins were separated on 10% or 12% and stained with Coomassie

Brilliant Blue G-250. Lane S, soluble crude extract from the recombinant E. coli; Lane P, purified

recombinant enzyme by GST affinity chromatography.

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Supplemental Figure S3. Competition and inhibition studies of LcL/ODC. Double reciprocal plots

between velocity and substrate concentration measured at four different concentrations of L-Lys (A)

or L-Orn (B) in the presence or absence of competitor. Inhibition of LcL/ODC by -

difluoromethylornithine (-DFMO, an irreversible inhibitor for ODC activity) as a function of L-Lys

(C) or L-Orn (D) concentration in the presence or absence of inhibitor. Each bar represents the mean

SD of 4 analytical replicates.

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Supplemental Figure S4. Overview of predicted protein structure of LcL/ODC complex homology

model with the Schiff base intermediate of putrescine (PUT) and pyridoxol-5-phosphate (PLP) at the

active site. Schiff base intermediate of PLP with PUT are presented as sticks and dots models (carbon,

yellow; oxygen, red; nitrogen, blue). Amino acids which involve in the catalytic site are colored in

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magenta. Squares indicate the active site. Each monomer is shown in gray or wheat color. A, predicted

protein structure of LcL/ODC. B, active site of predicted LcL/ODC protein structure. C, active site of

human-ODC protein structure. The black arrows indicate the critical structure change regarding the

extension of 310-helix, which could be responsible for accepting cadaverine and Put. The picture was

created by PyMOL.

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Supplemental Figure S5. Alignment of genomic sequences of putative ODCs from S. italica.

SiODC1 is interpreted as functional ODC-coding gene. SiODC2 is most likely pseudogene because

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the deletion of 2 nucleotides, as indicated by an arrow, causing a splicing modification of the transcript

and a loss of 64 nucleotides. Intron region is boxed; the respective intron sequences are given in lower

case.

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Table S1. Levels of amines and lycopodium alkaloids in each organ of L. clavatum and H. serrata

Content (pmol/mg FW)

L. clavatum H. serrata

Compound Leaf + Stem Root Strobilus Leaf Stem Root

Ornithine 6.43 1.10 2.48 1.22 2.02 0.86 ND ND 4.71 0.42

Lysine 95.40 18.11 3.13 0.58 26.27 4.95 250.35 42.16 302.61 52.54 41.06 6.02

Cadaverine ND ND ND ND ND ND

Put-conjugatesa 2.09 1.15 4.86 1.74 7.61 1.41 73.36 18.49 40.37 7.30 102.58 8.69

Cad-conjugatesb 73.31 5.27 70.07 5.41 56.78 7.58 644.15 66.71 336.17 9.54 714.59 74.89

Pelletierinec 3.38 1.28 1.87 0.33 1.85 0.37 83.10 13.08 16.56 0.75 0.56 0.15

Phlegmarinec ND ND ND 47.43 5.13 8.45 0.61 ND

Lycodinec 9.22 0.53 0.81 0.26 4.67 0.70 0.52 0.14 0.57 0.23 ND

Huperzine A ND ND ND 3471.79 312.87 2394.35 249.80 91.66 7.42

Data represent means SD the polyamines and alkaloids in different organs from pooled samples of L. clavatum (n = 4), H. serrata

(n = 4).

Analytical replicate, n = 56. ND = not detected.

a, Putative putrescine (Put)-conjugates are predicted based on m/z from CE-MS, including cinnamoyl-, coumaroyl-, feruloyl-,

dincinnamoyl-, dicoumaroyl-, feruloylcaffeoyl-, and diferuloyl-putrescine with the corresponding m/z 219.13, 235.14, 265.15,

349.21, 381.16, 413.14, and 441.23, respectively. The total amount is calculated on the mass response factor of putrescine as the

standard.

b, Putative cadaverine (Cad)-conjugates are predicted based on m/z from CE-MS, including cinnamoyl-, coumaroyl-, caffeoyl-,

feruloyl-, and disinapoyl-cadaverine with the corresponding m/z 233.15, 249.15, 265.15, 279.18, and 515.26, respectively. The total

amount is calculated on the mass response factor of cadaverine as the standard.

c, Putative pelletierine, phlegmarine, and lycodine are predicted based on m/z from CE-MS with the corresponding m/z 142.12,

251.24, and 243.18, respectively.

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Table S2. Levels of amines in each organ of G. max and Lotus japonicus

Content (pmol/mg FW)

G. max Lotus japonicus

Compound Leaf Root Leaf Root

Ornithine 1356.77 141.44 5.65 1.94 35.35 2.53 3.60 1.20

Lysine 1348.30 128.83 45.73 1.74 96.20 6.94 53.03 14.82

Putrescine 19.52 6.24 493.41 108.69 15.32 5.11 23.34 11.16

Cadaverine 20.21 15.42 1600.27 54.06 ND ND

Put-conjugatesa 65.75 11.35 37.42 1.72 95.36 7.79 ND

Cad-conjugatesb 39.67 2.94 27.13 10.99 759.80 58.64 29.86 12.42

Data represent means SD the amines in different organs from pooled samples of G. max and Lotus japonicus, 30 days old plants (n

= 4).

Analytical replicate, n = 56. ND = not detected.

a, Putative putrescine (Put)-conjugates are predicted based on m/z from CE-MS, including cinnamoyl-, coumaroyl-, feruloyl-,

dincinnamoyl-, dicoumaroyl-, feruloylcaffeoyl-, and diferuloyl-putrescine with the corresponding m/z 219.13, 235.14, 265.15,

349.21, 381.16, 413.14, and 441.23, respectively. The total amount is calculated on the mass response factor of putrescine as the

standard.

b, Putative cadaverine (Cad)-conjugates are predicted based on m/z from CE-MS, including cinnamoyl-, coumaroyl-, caffeoyl-,

feruloyl-, and disinapoyl-cadaverine with the corresponding m/z 233.15, 249.15, 265.15, 279.18, and 515.26, respectively. The total

amount is calculated on the mass response factor of cadaverine as the standard.

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Table S3. Accession numbers of sequences used for phylogenetic analysis

Name

GenBank/DDBJ

Accession

Number

Landmark region

on Phytozome database/ 1KP

project Accession Number

Amino acid

at positions

112 and 314

Actinidia chinensis QAUE-2025470 G/H

Adiantum tenerum BMJR-2000153 G/H

Andreaea rupestris WOGB-2094269 G/H

Anemia tomentosa CQPW-2004067 G/H

Anthoceros formosae IQJU-2003727 G/H

Argemone mexicana-root SMZF-2012966 D/H

Asplenium platyneuron KJZG-2012896 G/H

Atrichum angustatum ZTHV-2016440 G/H

Austrocedrus chilensis YYPE-2069763 G/H

Baptisia australis BAL04979 S/F

Brachypodium distachyon XP_003578555 G/H

Brugmansia sanguinea AIOU-2069900 N/H

Calycanthus floridus FALI-2121480 G/H

Cannabis sativa-4 samples combined BJSW-2070419-BJSW G/H

Cannabis sativa-core DGNP-2037820 G/H

Cannabis sativa-stem PMRP-2040020 G/H

Cannabis sativa-stem peel SFZX-2041247 G/H

Capsicum annuum Q8S3N2 N/H

Ceratocapnos vesicaria UDHA-2027520 N/H

Cheilanthes arizonica DCDT-2016720 G/H

Chlorokybus atmophyticus AZZW-2001527 G/H

Cicer arietinum XP_004500902 N/F

Cinnamomum_camphora BCGB-2010509 G/H

Citrus clementia XP_006442771 N/E

Citrus sinensis-1 KDO63974 N/E

Citrus sinensis-2 KDO63973 N/E

Coccomyxa subellipsoidea C-169-1 XP_005643256 G/H

Coccomyxa subellipsoidea C-169-2 XP_005642930 G/H

Corydalis linstowiana ZGQD-2011518 N/H

Cylindrocystis brebissonii-M2213 YOXI-2008283 G/H

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Name

GenBank/DDBJ

Accession

Number

Landmark region

on Phytozome database/ 1KP

project Accession Number

Amino acid

at positions

112 and 314

Cylindrocystis cushleckae JOJQ-2001281 G/H

Cystopteris fragilis LHLE-2015185 G/H

Cystopteris reevesiana RICC-2001678 G/H

Datura metel JNVS-2050848 N/H

Datura stramonium P50134 N/H

Davallia fejeensis OQWW-2026291 G/H

Dennstaedtia sp. MTGC-2006101 G/H

Deparia lobato-crenata FCHS-2004087 G/H

Didymochlaena truncatula RFRB-2035525 G/H

Dipteris conjugate MEKP-2006943 G/H

Diselma archeri GKCZ-2016313 G/H

Echinosophora koreensis BAK32801 S/F

Encephalartos barteri GNQG-2085630 G/H

Entransia fimbriat BFIK-2030785 G/H

Erythroxylum coca AEQ02350 N/H

Erythroxylum_coca RPPC-2071550 N/H

Eschscholzia californica-5 samples

combined EVOD-2115179-EVOD G/H

Glycine max-1 CAD91349 S/Y

Glycine max-2 NP_001236340 S/Y

Glycyrrhiza glabra PEZP-2069738 S/F

Gossypium raimondii-1 Chr07:48,680,583..48,681,878 G/H

Gymnocarpium dryopteris HEGQ-2003697 G/H

Homo sapiens NP_002530 G/H

Hordeum vulgare subsp. vulgare BAJ99170 G/H

Huperzia myrisinites CBAE-2002663 G/Y

Huperzia selago GTUO-2003077 G/Y

Huperzia selago-2 samples combined YHZW-2003381 G/Y

Huperzia serrata-1 DDBJ_AB915696 G/Y

Huperzia serrata-2 DDBJ_AB915697 G/Y

Huperzia squarrosa GAON-2005558 G/Y

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Name

GenBank/DDBJ

Accession

Number

Landmark region

on Phytozome database/ 1KP

project Accession Number

Amino acid

at positions

112 and 314

Hymenophyllum bivalve QIAD-2059485 G/H

Ipomoea lindheimeri NAUM-2054533 N/H

Ipomoea pubescens EMBR-2057952 N/H

Klebsormidium subtile FQLP-2008974 G/H

Laurelia sempervirens WAIL_2069374 G/H

Leiosporoceros dussii FANS-2000389 G/H

Lindsaea linearis NOKI-2009815 G/H

Linum hirsutum HNCF-2007775 S/H

Linum leonii AEPI-2051648 S/H

Linum lewisii BHYC-2052920 S/H

Linum usitatissimum-3 samples combined POZS-2025830-POZS S/H

Linum usitatissimum-stem_region_3 OZJZ-2018018 S/H

Linum_grandiflorum MYVH-2061705 S/H

Lotus japonicus CAE02644 S/H

Lupinus angustifolius BAK32797 S/F

Lycium barbarum LWCK-2013819 N/H

Lycium sp. OSMU-2080375 N/H

Lycopersicon cheesmanii-1 UGJI-2022873 N/H

Lycopodiella apressa ULKT-2002309 G/Y

Lycopodium clavatum DDBJ_AB915695 G/Y

Lycopodium deuterodensum PQTO-2083290 G/Y

Lygodium japonicum PBUU-2001147 G/H

Manihot esculenta-1 scaffold02943:508,987..510,228 N/H

Marchantia paleacea-non mycorrizal HMHL-2055161 G/H

Marchantia polymorpha JPYU-2010158 G/H

Medicago truncatula XP_003603845 N/Y

Mesostigma viride KYIO-2004640 G/H

Mesotaenium endlicherianum WDCW-2048528 G/H

Microcachrys tetragona MHGD-2013075 G/H

Microstrobos fitzgeraldii BBDD-2076950 G/H

Mougeotia sp. ZRMT-2009586 G/H

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Name

GenBank/DDBJ

Accession

Number

Landmark region

on Phytozome database/ 1KP

project Accession Number

Amino acid

at positions

112 and 314

Myriopteris eatonii GSXD-2016209 G/H

Nelumbo nucifera PZRT-2063418 N/Y

Nicotiana benthamiana BAF91874 N/H

Nicotiana glauca CBX19979 N/H

Nicotiana glutinosa AAG45222 N/H

Nicotiana sylvestris MKZR-2110363 N/H

Nicotiana tabacum-1 AAQ14852 N/H

Nicotiana tabacum-2 AAF42973 N/H

Nicotiana tabacum-3 LC030209 N/H

Notholaena montieliae YCKE-2012615 G/H

Nothotsuga longibracteata AREG-2009033 G/N

Nuphar advena WTKZ-2001681 N/Y

Oryza sativa-1 BAC79204 G/H

Pallavicinia lyellii YFGP-2012066 G/H

Panicum virgatum-1 sg0.contig142346:1,104..2,330 G/H

Panicum virgatum-2 sg0.contig76766:1,714..2,946 G/H

Papaver somniferum-leaf BMRX-2025862 N/H

Pellia cf. Epiphylla PIUF-2092589 G/H

Phaseolus vulgaris-1 ESW08125 S/H

Phaseolus vulgaris-2 ESW08124 S/D

Phylloglossum drummondii ZZEI-2003348 G/Y

Pilgerodendron uviferum ETCJ-2010524 G/H

Pinus ponderosa JBND-2071105 G/K

Pinus radiata DZQM-2004322 G/H

Plagiogyria japonica UWOD-2140412 G/H

Polypodium amorphum YLJA-2073839 G/H

Polypodium glycyrrhiza CJNT-2004570 G/H

Populus trichocarpa-1 XP_002300677 N/H

Populus trichocarpa-2 XP_002307756 N/H

Prumnopitys andina EGLZ-2009798 G/H

Pseudolycopodiella caroliniana UPMJ-2018782 G/Y

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Name

GenBank/DDBJ

Accession

Number

Landmark region

on Phytozome database/ 1KP

project Accession Number

Amino acid

at positions

112 and 314

Pseudotsuga menziesii IOVS-2056205 G/H

Psilotum nudum QVMR-2007066 G/H

Pteris ensigormis FLTD-2016082 G/H

Pteris vittata POPJ-2011761 G/H

Retrophyllum minus VGSX-2010878 G/H

Riccia berychiana WJLO-2037974 G/H

Saccharomyces cerevisiae NP_012737 N/H

Sceptridium dissectum EEAQ-2089752 G/H

Selaginella moellendorffii XP_002977120 G/H

Setaria italica-1 XP_004957520 G/H

Setaria italica-2a scaffold_2:38,865,291..38,866,521 G/Y

Solanum dulcamara GHLP-2057325 N/H

Solanum lycopersicum NP_001234616 N/H

Solanum ptychanthum DLJZ-2056606 N/H

Solanum sisymbriifolium NMDZ-2096881 N/H

Solanum tuberosum XP_006342090 N/H

Solanum xanthocarpum LQJY-2080087 N/H

Sophora flavescens BAK32800 S/F

Sorghum bicolor-1 XP_002462765 G/H

Sorghum bicolor-2 XP_002450970 G/H

Sphaerocarpos texanus HERT-2008826 G/H

Sphagnum palustre RCBT-2029064 G/H

Spirogyra sp. HAOX-2004748 G/H

Stangeria eriopus KAWQ-2055741 G/H

Taiwania cryptomerioides QSNJ-2066599 G/H

Taxodium distichum FHST-2005753 G/H

Tetraclinis sp. CGDN-2069492 G/H

Themopsis lupinoides DDBJ_AB915698 C/F

Theobroma cacao-1 EOY15148 N/H

Theobroma cacao-2 EOY15149 G/H

Thermopsis chinensis BAL04980 S/F

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Name

GenBank/DDBJ

Accession

Number

Landmark region

on Phytozome database/ 1KP

project Accession Number

Amino acid

at positions

112 and 314

Thladiantha villosula AXAF-2064431 N/H

Thyrsopteris elegans EWXK-2122583 G/H

Tmesipteris parva ALVQ-2022897 G/H

Trypanosoma brucei AAA30218 G/H

Vittaria lineata SKYV-2016271 G/H

Woodsia scopulina YJJY-2078159 G/H

Xenopus laevis P27120 G/H

Zea mays-1 DAA42143 G/H

Zea mays-2 DAA62501 G/H

Zea mays-3 NP_001142154 G/H

a, pseudogene which was not used in the phylogenetic tree

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Table S4. List of primers used in this study

1. ODC and L/ODC cloning

Gene Primer name Sequence

LcL/ODC LDC-degen-F TAYGCIGTIAARTGYAAYCCI

LDC-degen-R RTCRCAIGTIGGICCRAA

Lcl-3RACE TCTACGGCACAATGAACTGC

Lcl-5RACE-A2-1 GGCGACGGATTACATTTCAC

Lcl-5RACE-A1-1 TTTGCTTGCACAGTCGAATC

Lcl-5RACE-S1-1 AGGTGATATCCATGGGCGTA

Lcl-5RACE-S2-1 CGGAGTGAATCTCACCACCT

Lcl-5RACE-RT-1 [Phos]GCGTTGGGATTGTTG

HsL/ODC LDC-degen-F TAYGCIGTIAARTGYAAYCCI

LDC-degen-R RTCRCAIGTIGGICCRAA

Hse-3RACE-1 TCTACGGCACAATGAACTGC

Hse-3RACE-2 CGAGAGGAGGTGAGGGAGTATTGGATA

Hse-5RACE-A2-1 GGCGTTGGGACTGTGCACCT

Hse-5RACE-A1-1 TGTGTGATGGCATCTTGCACGGA

Hse-5RACE-S1-1 GAGCCGATGACAGGAACTCAAA

Hse-5RACE-S2-1 GGTCAAGTATGGAGCTCTCTCT

Hse-5RACE-RT-1 [Phos]GCTCAGGGCCTTCTCGAACACT

TlL/ODC LDC-degen-F TAYGCIGTIAARTGYAAYCCI

LDC-degen-R RTCRCAIGTIGGICCRAA

Tfa-3RACE-F1 TGGATCGACGATGGGATCTACGG

Tfa-3RACE-F2 CGTGCTCACCACTCGCGTGTA

2. Site-directed mutagenesis

Gene Primer name Sequence

LcL/ODC-Y344H Lcl-L/ODC-Y344H-F CTCATCCATGATCACGCTGTCCTCTGT

Lcl-L/ODC-Y344H-R ACAGAGGACAGCGTGATCATGGATGA

NtODC3-H344Y Nta-ODC-H344Y-F11 GTACTTTACGACTATGCGACGGTGA

Nta-ODC-H344Y-R12 TCACCGTCGCATAGTCGTAAAGTAC

NtODC3-H344F Nta-ODC-H344F-F21 GTACTTTACGACTTTGCGACGGTGA

Nta-ODC-H344F-R22 TCACCGTCGCAAAGTCGTAAAGTAC

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3. Protein expression in E. coli

Gene Primer name Sequence

LcL/ODC-WT BamHI-Lcl-L/ODC-Y344H-F GGATCC-ATGGCTTGCAATTCACTGAATGTGTA

Sma-Lcl-L/ODC-Y344H-R CCCGGG-TCATTCGCTGTCCTCGCTG

NtODC3-WT BamHI-Nta-ODC-F GGATCC-ATGGCCGGCCAAACAATAATC

XhoI-Nta-ODC-R CTCGAG-TCAGCTTGGATAAGTATAAGC

NtODC3-H344Y BamHI-Nta-ODC-H344Y-F1 GGATCC-ATGGCCGGCCAAACAATAATC

XhoI-Nta-ODC-H344Y-R1 CTCGAG-TCAGCTTGGATAAGTATAAGC

NtODC3-H344F BamHI-Nta-ODC-H344Y-F2 GGATCC-ATGGCCGGCCAAACAATAATC

XhoI-Nta-ODC-H344Y-R2 CTCGAG-TCAGCTTGGATAAGTATAAGC

4. Real-time PCR

Gene Primer name Sequence

LcL/ODC Lcl-L/ODC-qF TGCGGAGCCTGGTAGATACT

Lcl-L/ODC-qR GCAGTTCATTGTGCCGTAGA

GmODC3 Gma-L/ODC-qF ACGCAAACCCATGCAAATCC

Gma-L/ODC-qR TCGAGGGAGTCGTAGGTTGT

LjODC Lja-ODC-qF TGCGAAGACCTACCCTACCA

Lja-ODC-qR TCGGGAACACAAGCCAATCA

Lctub Lcl-tub-qF GTTTTCGGTCAATCGGGAGC

Lcl-tub-qR TCGACGAGTTCAGCACCTTC

Gmtub Gma-tub-qF CACAGAGGCAGAGAGCAACA

Gma-tub-qR CCTCGTCCTCATACTCCCCA

Ljtub Lja-tub-qF GAAGCTCGCTACACCGACAT

Lja-tub-qR ATGGAGACGAGGGAATGGGA

5. Localization

Gene Primer name Sequence

LcL/ODC-Met1-GFP SalI-LclDC-F GTCGAC-ATGGCTTGCAATTCACTGAATGTGTA

SalI-LclDC-R GTCGAC-TTCTTCGCTGTCCTCGCTG

GFP-LcL/ODC-Met1 BsrGI-LclDC-F TGTACA-ATGGCTTGCAATTCACTGAATGTGTA

NotI-LclDC-stop-R GCGGCCGC-TCATTCGCTGTCCTCGCTG

LcL/ODC-Met3-GFP SalI-LclDC2-chl-F GTCGAC-ATGCCTCTCACTGCTCTA

SalI-LclDC-R GTCGAC-TTCTTCGCTGTCCTCGCTG

GFP-LcL/ODC-Met3 BsrGI-LclDC2-chl-F TGTACA-CGATGCCTCTCACTGCTCTAG

NotI-LclDC-stop-R GCGGCCGC-TCATTCGCTGTCCTCGCTG

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6. Plant transformation

Gene Primer name Sequence

LcL/ODC LclDC-attB1-F AAAAAGCAGGCTGGATGGCTTGCAATTCACTG

LclDC-attB1-R2 AGAAAGCTGGGTCTCATTCGCTGTCCTCGCTGGT

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Supplemental Data S1. Highly conserved amino acid alignment without gaps for the construction

of phylogenetic tree in Figure 2

>F_Lupinus_angustifolius

YAVKCNPNPSLLGVLAALGSSFDCASRAEIESVLSLGVSPDRIIYANPCKSESHIKYAAT

VGVNVTTFDSKEEIHKIKKWHPKCELLIRIKPPQDNLGLKYGAPEEVKPLLQAAKDAELK

VVGVSFHIGSGGADSRTYHGAIAAAKSVFDMASELGMMKALEDNFGGVVVIGEPGRYFAE

SPFTLASKVIGKRVREYWIDDGIYGSLNCIMYDFATVTCTPLYPS

>F_Sophora_flavescens

YAVKCNPNPCLLGALAALGSSFDCASRAEIESVLSLGVSPDKIIYANPCKSESHIKYAAS

VGVNVTTFDSKEEIDKIRKWHPKCELLIRIKPPGDNLGLKYGAPEEVMPLLQAAQNAGLK

VTGVSFHIGSGGADSQTYHGAIAAAKRVFDMASELNMMKALQVHFGGVVVIGEPGRYFAE

SAFTLASKVIGKRVREYWIDDGIYGSLNCIMFDFATVTCSPLYPS

>F_Echinosophora_koreensis

YAVKCNPNPCLLGALAALGSSFDCASRAEIESVLSLGVSPDRIIYANPCKSESHIKYAAS

VGVNVTTFDSKEEIEKIRKWHPKCELLIRIKPPGDNLGLKYGAPEEVMPLLQAAHNAGLK

VTGVSFHIGSGGADSQTYHGAIAAAKRVFDMASELNMMKALQVHFGGVVVIGEPGRYFAE

SAFTLASKVIGKRVREYWIDDGIYGSLNCIMFDFATVTCSPLYPS

>F_Themopsis_lupinoides

YAVKCNPNPSLLGALAALGSCFDCASRAEIESVLSLGVKPDRIIYANPCKSESHIKYAAC

VGVNVTTFDSKEEIEKIRKWHPKCELLIRIKPPQDNLGLKYGAPEEVMPLLETARDAGLK

VTGVSFHIGSGGADSRTYHGAIEASRRIFDMASELGMMKALEANFGGIVVIGEPGRYFAE

SAFILASKVIGKRVREYWIDDGIYGSLNCIMYDFATVTCSPLYPS

>F_Thermopsis_chinensis

YAVKCNPNPSLLGALAALGSSFDCASRAEIESVLSLGVKPNRIIYANPCKSESHIKYAAS

VGVSVTTFDSKEEIEKIKKWHPKCELLIRIKPPQDNLGLKYGAPEEVMPLLQAARDAGLK

VTGVSFHIGSGGADSRTYHGAIEASRRIFDMASELGMMKALEANFGGIVVIGEPGRYFAE

SAFTLASKVIGKRVREYWIDDGIYGSLNCIMYDFATVTCSPLYPS

>F_Baptisia_australis

YAVKCNPNPSLLGALAALGSSFDCASRAEIESVLSLGVKPDRIIYANPCKSESHIKYAAS

VGVNVTTFDSKEEIEKIRKWHPKCELLIRIKPPQDNLGLKYGAPEEVMPLLQAARDAGLK

VTGVSFHIGSGGADSRTYHGAIETSRRIFDMASELGMMKALEANFGGIVVVGEPGRYFAE

SAFTLASKVIGKRVREYWIDDGIYGSLNCIMYDFATVTCSPLYPS

>Y_Lycopodium_clavatum

YAVKCNPSPPLLSTMAALGAGFDCASKSELEQVISMGVSPQRIIFANPCKMPSHIKHASS

VGVNLTTYDCEHEVTKIKLNNPNAKLLLRLRADDLWLGVKYGATSEVEHLLMAAANAQVD

VVGVSFHIGSGASDARSYLDAIAAARKVFEKALALGLMHALDQYFPGVSIIAEPGRYFAE

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APTTLATMVYGKRVREYWINDGIYGTMNCLIHDYAVLCPRPLYKS

>Y_Huperzia_serrata_1

YAVKCNPSPSLLSTLAALGAGFDCASQSELELVTSMGVSAQRIIFANPCKMPSHIKYATS

VGVNLTTYDCEHEVRKVKVHSPNAKLLLRLRADDRWLGVKYGASSEVEHLLMAVANAQVD

VVGVSFHIGSGASDARSYLDAIAAARGVFEKALSMGLMHALEQYFPGVSIIAEPGRYFAE

APTTLAAMIYGKRVREYWINDGIYGTMNCLIHDYAVLCPRPLHKS

>Y_Huperzia_serrata_2

YAVKCNPSPSLLSTLAALGAGFDCASQSELELVTSMGVSAQRIIFANPCKMPSHIKYATS

VGVNLTTYDCEHEVRKVKVHSPNAKLLLRLRADDRWLGVKYGASSEVEHLLMAAANAQVD

VVGVSFHIGSGASDARSYLDAIAAARGVFEKALSMGLMHALEQYFPGVSIIAEPGRYFAE

APTTLAAMIYGKRVREYWINDGIYGTMNCLIHDYAVLCPRPLHKS

>F_Cicer_arietinum

YAVKCNPNLSLIGTLASLGSNFDCASRAEIEAVLSLGVSPDRIIYANPCKSESHIKYAAN

VGVNITTYDSVGEIDKIKKWHPKCELVLRIKPQEDSLGLKYGAVEEVPELLKAADVAGLK

VIGVSFHIGSGGGNAMAYHGAIALAKNVFETASLLGMMKAIKTYFGDLVVIGEPGRYFAE

TSFTLATKIIGKRLKEYWIDDGIYGTLNNIMFDFAIVSCTPMYAS

>Y_Glycine_max_1

YAVKCNPNLSLIGALAALGSSFDCASKAEIESVLSLGVSPDRIIYANPCKSESHIRYAAS

VGVNVTTYDSIDEVEKIRKCHPTCELLLRIKPPQDTLGLKYGAPEEVDELLQAAHEAGLK

VTGVSFHIGSGGADTRAYHGAISAAKNVFESASRLGLMGAIEGSFGGLVVIGEPGRYFAE

TAFTLATRVIGKRVREYWIDDGIYGTLNNIVFDYATVTCMPLYPS

>Y_Glycine_max_2

YAVKCNPNLSLIGALAALGSSFDCASKAEIESVLSLGVSPDRIIYANPCKSESHIRYAAS

VGVNVTTYDSLDEVEKIRNCHPTCELLLRIKPPQDTLGLKYGAPEEVHELLQAAHEAGLK

VTGVSFHIGSGGADTRAYDGAISAAKNVFEMASGLGLMRAIQASFGGLVVIGEPGRYFAE

TAFTLATRIIGKRVREYWIDDGIYGTLNNIVFDYATVTCMPLYPS

>Y_Medicago_truncatula

YAVKCNPNISLIGTLASLGSNFDCASRAEIESVLSLGVSPDKIIYANPCKSESHIKYAAS

VGVNVTTFDCAGEVEKIKKWHPKCELLLRIKPEEDSLGLKYGAHNEVPELLKAADMAGLK

VTGVSFHIGSGGADAKAYHGAILLAKEVFETASRLGMMKAIKTHFGDLVVIGEPGRYFAE

TAFTLATKVIGKRMREYWIDDGIYGTLNNIVFDYAIVKCMPLYPS

>H_Lotus_japonicus

YAVKCNPDISLIGALAALGSSFDCASKAEIQIVLSLGISPDRIVYANPCKSESDIKYAAT

VGVNLATYDSVYEVDKVQKWHPKCELLLRIKYDSEALGVKYGAPEEVPELLKAAEAAGVN

VTGVSFHIGSGGADPLALSGAIEAAKSVFEMASHFGMMSAILAHFGGLVVIAEPGRYFTE

TAFTLVSRVIGKRLREYWINDGVYGSISNIIYDHATIRCAPLYPT

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>H_Populus_trichocarpa-1

YAVKYNPVPALLGSLAALSSNFDCASQAEIELVLSLGVSLDRIVYANPCKPGSHIKYAAS

VGVNLTTFDSKEELDKIQKWHPKCALLIRIKALDDCLGSKYGAPEEVTPFLEAAQTARLN

VVGVSFHIGNRATYSQAYEGAIASAKSVFEAAARFGMMTALQAYFPGLTIISEPGRFFAE

SPFTLATNVIGKRLREYWINDGIYGSLNCILNDHATITCTPLYSS

>H_Populus_trichocarpa-2

YAVKCNPDPALLGSLAALGSNFDCASRAEIESVLSLGVSPNRIVYANPCKQESHIKYAAS

VGVNLTTFDSKEELDKIRKWHSKCALLIRIKAPDDCLGPKYGAPEEVTPLLQAAQTAQLN

VVGVSFHIGSGATRSRAYEGAIASAKSVFEAAVRLGMMKALQAYFPGLTVISEPGRFFAE

SAFTLATNIIGKRLREYWINDGIYGSMNCILYDHATITCTPLYSS

>H_Manihot_esculenta-1

YAVKCNPDPALTGTLAALGSNFDCASRVEIESILSLGVAPERIIYANPCKAESHIKYAAS

VGVNLTTFDSKEELEKIRKCHPQCALLIRVKAPDDCLGPKFGAPEEVTPLLQAAKVARLK

VVGVSFHIGSGATHSRAYRGAIAAAKTVFEAATRLGMMNALQAYFPGLTIISEPGRFFAE

SAFTLATNIIGKRLREYWINDGIYGSMNCILYDHATITCTPLYSS

>H_Phaseolus_vulgaris-1

YAVKCNPNLSLIGALATLGASFDCASKAEIEAVLSLGVSPDRIIYANPCKSASHIRYAAT

VGVKVTTYDSKDEVEKIRKYHPTCELLLRIKPPQECLDLKFGAPEEVPELLSVAHAAGLK

VTGVSFHIGSGGGDAQAYHGAISAAKSVFDAASRLGMMRAIQDSFGELVVIGEPGRYIAE

TAFTLATKVVGKRLREYWIDDGIYGTLNNILFDHATVTCMPLYSS

>H_Theobroma_cacao-1

YAVKCNPSPALLREMAALGSNFDCASRAEIEAILALGVSPDRIVFANPCKAESHIKYAAS

VGVNLTTFDSKDELEKIRKWHPECALLIRIKPPETFLGAKFGAPEEVVPLLQAAQAAKFT

VPGVSFHIGSGATHFRAFEEAIAAAKTVFEKAAHLGMMHALQKYFFGLKVMAEPGLFFAQ

SSFTLVASIIGKRLREYWINDGIYGSMNFLLYDHDDVILTPLYDS

>H_Theobroma_cacao-2

YAVKCNPNPALLGALATLGSGFDCASKAEIESVLSLGVSPGRIIFANPCKAESHIKYAAT

VGVNLTTFDSKEELEKIKKWHPKCALLIRVKAPDDCLGPKYGAPEEVTPLLQAAQTARLT

VTGVSFHIGSGAMQFRAYREAIAAAKTVFETAARLGMMHALQAYFPSLTVIAEPGRFFAE

SAFTLATNIIGKRLREYWINDGIYGSMNCILYDHAVVTCMPLYDS

>H_Gossypium_raimondii-1

YAVKCNPNPAFLKEMAALGTGFDCASLPEIETILSLGVSPDRIVFANTCKPESHIKYAAK

FGVNLTTFDSNCELEKIKKWHPKCALLIRIKVPETFFGSKFGAPEEIVPLLKAAQEAKLQ

VVGVSFHIGSRAINFHAFEDAIGAAKTTFDTAAQLGLMHALQKYFPALKIIAEPGRFFAN

SPFTLTTSVIGKRVKEYWISDGISGSMNFLKYDHDEVICTPLWSS

>H_Solanum_tuberosum

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YAVKCNPEPSFLSMLSAMGSNFDCASRAEIEYVLSLGISPDRIVFANPCKPESDIIFAEK

IGVNLTTYDSEDEVYKIRKHHPKCELLLRIKPMNDCMGPKYGAPEEIEPLLRTAQAARLT

VSGVSFHIGSGDADSNAYLGAIAAAKQVFETATQLGMMTALETHFQELTIIAEPGRFFAE

TAFTLATTIIGKRLKEYWINDGLYGSMNCVLYDHATVTATPLFPS

>H_Solanum_lycopersicum

YAVKCNPEPSFLSMLSAMGSNFDCASRAEIEYVLSHGISPDRIVFANPCKPESDIIFAEK

IGVNLTTYDSEDEVYKIRKHHPKCELLLRIKPMTDCMGPKYGAPEEIEPLLRTAQAARLT

VSGVSFHIGSGDADSNAYLGAIAAAKQVFETAAQLGMMTALETHFHELTIIAEPGRFFAE

TAFTLATTIIGKRLKEYWINDGLYGSMNCVLYDHATVTATPLFPS

>H_Datura_stramonium

YAVKCNPEPSFLSMLSAMGSNFDCASRAEIEYVLSLGISPDRIVFANPCKPESDIIFAAK

VGVNLTTFDSEDEVYKIRKHHPKCELLLRIKPMDDCMGPKYGAPEEVEPLLRTAQAARLT

VSGVSFHIGSGDADSKAYLGAIAAAKGVFETAARFGMMTALEQHFHELTIIAEPGRFFAE

TAFTLATTIIGKRLREYWINDGLYGSMNCVLYDHATVNATPLFPS

>H_Capsicum_annuum

YAVKCNPEPSFLSMLAAMGSNFVCASRAEIEYVLSLGISPERIVFANPCKPESDIIFAEK

VGVNLTTYDSEDEVYKIKKHHPKCELLLRIKPMNDCMGPKYGAPEEIEPLLRIAQASRLT

VSGVSFHIGSGDADSNAYLGAIAAAKQVFETAAKFGMMNALQQHFSELTIIAEPGRFFAE

TAFTLATTIIGKRLREYWINDGLYGSMNCVLYDHATVTATPLFPS

>H_Erythroxylum_coca

YAVKCNPEPALLGSLAAMGANFDCASRAEIEAVLSLRVSPDRIVYANPCKQESHIKYAAS

VGVNLTTFDSKDELEKMRKWHPKCALLLRVKAPEDCLGPKYGAPEEVIPLLQAAQAARLS

VVGASFHIGSGATHFSSYRGAIAEAKKVFETAVKMGMMTALQTYFPGLTIISEPGRFFAE

SAFTLATNVIGRRLREYWINDGIYGSMNCILYDHATVTCKPLYNS

>H_Nicotiana_benthamiana

YAVKCNPEPSFLSILSAMGSNFDCASRAEIEYVLSLGISPDRIVFANPCKPESDIIFAAK

VGVNLTTYDSEDEVYKIRKHHPKSELLLRIKPMLDCMGPKYGAPEEVDPLLRAAQTARLT

VSGVSFHIGSGDADSNAYLGAIAAAKEVFETAAKLGMMTALKQHFDGLAIIAEPGRFFAE

TAFTLATTIIGKRLREYWINDGLYGSMNCVLYDHATVNATPLFPT

>H_Nicotiana_tabacum_1

YAVKCNPEPSFLSILSAMGSNFDCASRAEIEYVLSLGISPDRIVFANPCKPESDIIFAAK

VGVNLTTYDSEDEVYKIRKHHPKSELSVRIKPMLDSMGPKYGAPEEVDPLLRAAQAARLT

VSGVSFHIGSGDADSNAYLGAIAAAKEVFETAAKLGMMTALKQHFDELTIIAEPGRFFAE

TAFTLATTIIGKRLREYWINDGLYGSMNCVLYDHATVNATPLFPT

>H_Nicotiana_tabacum_2

YAVKCNPEPSFLSILSAMGSNFDCASRAEIEYVLSLGISPDRIVFANPCKPESDIIFAAK

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VGVNLTTYDSEDEVYKIRKHHPKSELLLRIKPMLDCMGPKYGAPEEVDPLLRAAQAARLT

VSGVSFHIGSGDADSNAYLGAIAAAKEVFETAAKLGMMTALKQHFDELTIIAEPGRFFAE

TAFTLATTIIGKRLREYWINDGLYGSMNCVLYDHATVNATPLFPT

>H_Nicotiana_tabacum_3

YAVKCNPEPSFLSILSAMGSNFDCASRAEIEYVLSLGISPDRIVFANPCKPESDIIFAAK

VGVNLTTYDSEDEVYKIRKHHPKSELLLRIKPMFDCMGPKYGAPEEVEPLLRAAQAARLT

VSGVSFHIGSGDADSNAYLGAIAAAKEVFETAAKLGMMTALKQHFDELTIIAEPGRFFAE

TAFTLATTIIGKRLREYWINDGLYGSMNCVLYDHATVNATPLFPT

>H_Nicotiana_glutinosa

YAVKCNPEPSFLSILSAMGSNFDCASRAEIEYVLALGISPDRIVFANPCKPESDIIFAAK

VGVNLTTYDSEDEVYKIRKHHPKSELLPRIKPMFDCMGPKYGAPEEVEPLLRAAQAARLT

VSGVSFHIGSGDADSNAYLGAIAAAKEVFETAAKLGMMTALKQHFDELTIIAEPGRFFAE

TAFTLATTVIGKRLREYWINDGLYGSMNCVLYDHATVNATPLFPT

>H_Nicotiana_glauca

YAVKCNPEPSFLSILSAMGSNFDCASRAEIEYVLALGISPDRIVFANPCKPESDIIFAAK

VGVNLTTYDSEDEVYKIRKHHPKSELLLRIKPMFDCMGPKYGAPEEVEPLLRAAQAARLT

VSGVSFHIGSGDADSNAYLGAIAAAKEVFETAAKLGMMTALKQRFDELTIIAEPGRFFAE

TAFTLATTIIGKRLREYWINDGLYGSMNCVLYDHATVNATPLFPT

>H_Hordeum_vulgare_subsp._vulgare

YAVKCNPEPALLGALAALGAGFDCASRREMEAVLALGVQPGSIVYANPCKPEAHLEYAAE

VGVNLATYDSEEEVVKVKRCHPGCELILRIKGPDGVLGTKYGAEDEVLPLLRAAQREGLN

VAGVSFHVGSGASNTDVYRGAIEAARGVFDTAAALGMMRALERYFGPVEVIGEPGRYFAE

TAFTMAARVIGKRVREYWIDDGLYGTLSCIPMDHYVPRPRPLYTS

>H_Zea_mays-1

YAVKCNPEPALLGALAALGAGFDCASRAEMEAVLALGVPPGRIVYANPCKPEPHLEYAAG

AGVSLATYDTEDEVAKVARCHPGCQLLLRLKAPDGGLMNKYGAAHEVAPLLRAAQRAGVG

VAGVSFHVGSPVSRVDVYRGAIQAARAAFDQAVALGMMRALDRSFRPVEVVAEPGRYFAT

TAFTLAARVIGRRAREYWIDDGVYGSLNNVLMDHKAPRPRPLYAS

>H_Zea_mays-2

YAVKCNPDPALLGALAALGAGFDCASRAEIEAVLALGVRPGDIVYANPCKPEAHLEYAAE

VGVNLTTYDSEEEVAKVRRCHPGCELLLRLKGPDGVLGTKYGAPDEVVPLLRAAQRAGVG

VAGVSFHVGSGASNLHVYRGAIQAARAAFDAAAALGMMRALAHHFGPVEVIAEPGRYFAE

TAFTLAARVIGKRVREYWIDDGLYGSLNCIIMDHYVPTPRPLYTS

>H_Zea_mays-3

YAVKCNPEPALLGALAELGAGFDCASRAEIEAVLALGVPPSSIIYANPCKSEPHLEYAAA

AGVNLTTYDTEEEVAKVKRCHPRCELLLRLKGPDGCLGTKYGAADEVVPLLRAVQRAGVT

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VAGVSFHVGSPVARVGVYRAAIEAARAAFDEAAALGMMRALARSFGPVEVIGEPGRYFCE

TAFTLAARVIGKRVREYWIDDGLYGSLNNILMDHKVPRPRPLHTS

>H_Sorghum_bicolor-1

YAVKCNPDPALLGALAALGAGFDCASRAEIEAVLALGVQPRDIVYANPCKPEAHLEYAAE

VGVNLTTYDSEEEVAKVRRCHPACELLLRLKGPDGVLGTKYGAADEVVPLLRAAQRAGVG

VAGVSFHVGSGASILAVYSGAIQAARAAFDAAAALGMMRALAQHFGPVEVIGEPGRYFAE

TAFTLAARVIGKRVREYWIDDGLYGSLNCVIMDHYVPTPRPLYTS

>H_Sorghum_bicolor-2

YAVKCNPDPALLGALAALGAGFDCASRAEMEAVLALGVGVGDLIYANPCKAEPHLEYAAA

AGVALATYDTESEVAKVARCHPNCELLLRLKGPDGGLMNKYGAADEVSPLLRAAQRAGVR

VAGVSFHVGSPVSRVGVYRGAIESARAAFDAAAALGMMRALADAFGRVEVIAEPGRYFAE

TAFTLAARVIGRRAREYWIDDGLYGSLNNVLMDHKVPRPRPLHSS

>H_Setaria_italica-1

YAVKCNPDPALLGALAALGAGFDCASRAEIEAVLALGVHPRDIVYANPCKPEPHLEYAAE

VGVSLATYDSEEEVAKVKRCHPGCELLLRLKGPDGVLGTKYGAADEVVPLLRAAQRAGVS

VAGVSFHVGSGATNLGVYRGAIQAARAAFDAAAALGMMRALAQHFGPVEVIGEPGRYFAE

TALTLAARVIGKRVREYWIDDGLYGSLNCIIMDHYVPTPRPLYTS

>H_Panicum_virgatum-1

YAVKCNPDPALLGALAALGAGFDCASRAEIEAVLALGVRPRDIVYANPCKPEPHLEYAAQ

VGVNLATYDSEEEVAKVKRCHPDCELLLRLKGPDGVLGTKYGAADEIVPLLRAAQRAGVT

AAGVSFHVGSGASNLAVYRGAIEAARAAFDAAAALGMMRALAQHFGPVEVIGEPGRYFAE

TAFTLAARVIGKRVREYWIDDGLYGSLNCVIMDHYVPTPRPLYTS

>H_Panicum_virgatum-2

YAVKCNPDPALLGALAALGAGFDCASRAEIEAVLALGVRPRDIVYANPCKPEPHLEYAAE

VGVSLATYDSEEEVAKVKRCHPNCELLLRLKGPDGVLGTKYGAADEVVPLLRAAQCAGVT

VAGVSFHVGSGANNLAVYRGAIEAARAAFDAAAALGMMRALAQHFGPVEVIGEPGRYFAE

TAFTLAARVIGKRVREYWIDDGLYGSLNCIVMDHYVPTPRPLYTS

>H_Oryza_sativa-1

YAVKCNPDGAMLAALAALGAGFDCASRAEIEAVLALGVRPATIVYANPCKPEAHLEYAAE

VGVNLTTYDSEEEVAKVRRCHPRCELLLRIKAPDSVLGLKYGAPDEVLPLLRAAQREGVA

VAGVSFHVGSGASRADVYRGAIEAAREAFDAAAALGMMRALERHFGPVEVIGEPGRYFAE

TAFTLAARVIGKRLREYWIDDGLYGSLNCILMDHYVPRPRPLHAS

>H_Brachypodium_distachyon

YAVKCNPEPALLGALAALGAGFDCASRREIEAVLALGVEPGSIVYANPCKPEAHLEYAAS

VGVNLATYDSEEEVAKVKRCHPGCELILRIKGPDGVLGTKYGAPEEVVPLLRAAQRAGLN

VAGVSFHVGSGASNTDVYRGAIEAARGVFDAAAALGMMRALEKYFGPVEVIGEPGRYFAE

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TAFTMAARVIGKRVREYWIDDGLYGTLSCIPMDHYVPRPRPLFTS

>H_Selaginella_moellendorffii

YAVKCNPDPQLLSMLAALGAGFDVASKAELEAVTQLGVAPRNIIFANPCKLPSHITEAAK

AGVVYTTFDSEGELYKLKKYHPQAEVLLRFRADDTCLGVKYGAWDECYHLLEVAKTLGIK

VAGVAFHVGSGASDVNAFAEGIKAARKLFDMAESLGLMTALEEHFPMVRIIGEPGRFFAE

EAFSLAVLVFGCREVEYWINDGIYGSMNCLLYDHATLSVRALSDC

>H_Coccomyxa_subellipsoidea_C-169-1

YAVKCMPDRAMMSTLAALGTGFDCASPAEIDAVLSLGVPPERIIYAHPVKSPAQIRHAAA

RRVAMTTADSSGEMEKLAHWHPTAKVLLRIRADDACLGTKYGAVADAPGILAAAAALGVD

IVGVSFHVGSASRDPKAFEVAIRLARGVFDVGASLGLMRALDAHFPGYDIIAEPGRYFAE

AVGTLLCAVNGKRRADYWLSDGLYGSFNGILYDHMVPTPVALTTA

>H_Coccomyxa_subellipsoidea_C-169-2

YAVKCNNDEAILSALAALGAGFDCASDAELDMVLELGVPTGRIVFANACKRPRDIRRAAE

KQANLTTFDTASELAKLARWHPATRALLRIRADDPCLGNKYGAPSEVPALLQAAKEMGIE

VCGISFHVGSGATNPDAFSEAIALARTAFDAGTGLGFMDALALHFPGVRIIAEPGRYFAE

SCATFGSMVFGVRARDYWITDGIYGSMNSLLYDHATVAPRPLLRG

>H_Saccharomyces_cerevisiae

YAVKCNPDTKVLSLLAELGVNFDCASKVEIDRVLSMNISPDRIVYANPCKVASFIRYAAS

KNVMKSTFDNVEELHKIKKFHPESQLLLRIATDDSCLSTKYGCMENVDVLLKAIKELGLN

LAGVSFHVGSGASDFTSLYKAVRDARTVFDKAAEYGLLKALEEFFPGVDIIAEPGRYFVA

TAFTLASHVIAKRNAMIYTNDGVYGNMNCILFDHQEPHPRTLYPY

>H_Trypanosoma_brucei

YAVKCNDDWRVLGTLAALGTGFDCASNTEIQRVRGIGVPPEKIIYANPCKQISHIRYARD

SGVDVMTFDCVDELEKVAKTHPKAKMVLRISTDDSCLSVKFGAVEDCRFILEQAKKLNID

VTGVSFHVGSGSTDASTFAQAISDSRFVFDMGTELGFMHALEKHFPKLTIVAEPGRYYVA

SAFTLAVNVIAKKVFMYYVNDGVYGSFNCILYDHAVVRPLPQYPS

>H_Xenopus_laevis

YAVKCNDGKAIVKTLSILGAGFDCASKTEIQLVQSIGVSPERIIYANPCKQVSQIKYAAS

CGVEKMTFDSEVELMKVARNHPNAKLVLRIATDDSCLSVKFGALKTSRLLLERAKELNVD

IIGVSFHVGSGCTDPQTYVQAVSDARCVFDMGAELGFMHALDKYFPGVKIIAEPGRYYVA

SSFTLAVNIIAKKELMYYVNDGVYGSFNCILFDHAHVKPVLTYSS

>H_Homo_sapiens

YAVKCNDSKAIVKTLAATGTGFDCASKTEIQLVQSLGVPPERIIYANPCKQVSQIKYAAN

NGVQMMTFDSEVELMKVARAHPKAKLVLRIATDDSCLSVKFGALRTSRLLLERAKELNID

VVGVSFHVGSGCTDPETFVQAISDARCVFDMGAEVGFMYALDKYFPGVRIIAEPGRYYVA

SAFTLAVNIIAKKEFMYYVNDGVYGSFNCILYDHAHVKPLLQYSS

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>E_Citrus_clementina

YAVKCNPEPALLEALAALGSNFDCASRSEIEAVLALGVSPDRIIYANPCKPVSHIKYAAN

VGVNLTTFDSVEELHKIRKWHPKCDLLIRIKPPDDHLDSKYGVPQEIVPLLEAAEASGLS

VVGVAFHIGSAATKFAAYRGAIAAAKAVFETAARLGNMRALHAYFPLLRVISEPGRFFTY

SAFTLYTQIIGKRMRNYWINDGKYGSFDWVNYDEAIAKCTPLYNS

>E_Citrus_sinensis-1

YAVKCNPEPALLEALAALGSNFDCASRSEIEAVLALGVSPDRIIYANPCKPVSHIKYAAN

VGVNLTTFDSVEELHKIRKWHPKCDLLIRIKPPDDHLDSKYGVPQEIVPLLEAAEASGLS

VVGVAFHIGSAATKFAAYRGAIAAAKAVFETAARLGNMRALHAYFPLLRVISEPGRFFTY

SAFTLYTQIIGKRMRNYWINDGKYGSFDWVNYDEAIAKCTPLYNS

>E_Citrus_sinensis-2

YAVKCNPEPALLEALAALGSNFDCGSRSEIEAVLLLDVSPDRIIYANPCKPVSHIKYAAS

VGVNLTTVDSVEELDKIRNWHPKSDLLIRIKSPDDYLDSKYGAPQEIMPLLKAAEASGLS

VVGVSFHVGSEATNFAAFRGAIAAAKAVFDTAARTSNMRKLFKLIFLLKVISEPGRFFAA

SAFTLYAQIIGKRLREYWINDGKFGSLAWVTCDEAIAKCTPLYNS

>D_Phaseolus_vulgaris-2

YAVKCNPNLSLIGALAVLGASFDCASKAEIEAVLSLGVSPDRIIYANPCKSASHIRYAAT

VGVNVTTYDSKDEVEKIRKCHPTCELLLRIKPPQERLGVKFGAPEEVPELLSVAHAAGLK

VTGVSFHIGSGGENAQAYQGAISAAKSVFDAASRLGMMRAIQDSFGELVVIGEPGRYIAE

TAFTLATKVVGKRLREYWIDDGIYGTFNHMYFDDATFTCMPLYSS

>Y_2_PZRT-2063418-Nelumbo_nucifera

YAVKCNPDPALVSGLAALGANFDCASRAEIEAVLALGVSADRIIYANPCKSETHIRYAAG

VGVNLTTFDSKEEVEKLRKLHPRCRLLLRFKAPDDCLGPKYGAPEEVVPLLQAAHAAHLP

IVGVSFHVGSGATQFGAYSGAIAFARSVFDTAEGLGLMRALKTHFPGVTVISEPGRFFAE

TPFTLATTIIGKRIREYWINDGIYGSMNCLLFDYATITAQPLYTS

>Y_2_WTKZ-2001681-Nuphar_advena

YAVKCNPEPAFLSALAALGANFDCASRAEIEAVFALGVSADRIIYANPCKSESQIRYAAS

VGVNLTTYDSKEEVEKLRKLHPKCSLLLRIKVHDDWLGSKYGASEEVLPLLQAAHATGLP

VVGVSFHVGSGATESQAYASAIALARSVFDSATRLGMMRALKLHFPGVSFMAEPGQYFAG

TAFTLVANIIGKRLREYWINEGIYGSMNFLLHDYATLTVEPLHLS

>N_5_AREG-2009033-Nothotsuga_longibracteata

YSVKCNPEPALLSALATLAAGFECTSAAEIEDILKLGVSPHRIVYSNPCKAETQLKYAAN

VGVNLTTFDSIEEVEKIKKFHPRCALLLTMKVPDEFLGSKYGAPEEVGPLLQAAQRGGIA

VAGVSFHVGNGVSHYRVYTSAVAAVRGVFDTASRLGLLGALETYFPAVSVMGEPGRYFAE

SAFWLVTNVIGKRVREYWINDGIYGSMSCLLHDNAVLTALPLYRS

>H_5_BBDD-2076950-Microstrobos_fitzgeraldii

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YAVKCNPEPALLWALATLGVGFDCASRAEIEAVLAVGVSSDRIIYANPCKAETQLRYAAK

VGVNLTTFDSTEEVDKIKNSHPRCSLVLRIRAPEDCLGPKYGAPEEVAPLLQAAHRAGLS

VAGVSFHVGSGASNAGVYTGAIAAAKSVFQTAARLGLLRALDSYFPSVSLIGEPGRYFAE

SAFTLATNVIGKRLREYWINDGIYGSMNCLLYDHAVITALPLHRS

>H_5_CGDN-2069492-Tetraclinis_sp.

YAVKCNPEPLLLNSLAILGAGFDCASRAEIEAVLSLGVSADRIVYANPCKAESQLKYAAK

VGVNLTTFDSKEEIEKIRSSHPRCEVILRVKGQEDCLGSKYGAAEEIGPLLQAAQRAGLT

VAGVSFHVGSGAEHARAYTAAINAVKNAFDTASKLGLLKALSGNFPSISVIAEPGRYFAE

SAFSLATNIIGKRLREYWINDGIYGSMNCLLYDHAVITALPLYRS

>H_5_DZQM-2004322-Pinus_radiata

YAVKCNPDPTLLSALATLGSGFDCASRAEIEAILKLGVSADRIVYANPCKAETQLQYAAD

VGVNLTTFDSVDEVEKIRKFHPRCALLLRVKVPEECLGPKYGAPEEVGPLLEAAQSSGLA

VSGVSFHVGSGVARSRVYATAVGAVRGVFDTASRLGLLRALKTHFPEVSVIAEPGRYFAE

SAFTLATNVIGKRLREYWINDGIYGSMNCLLYDHAVITALPLFRS

>H_5_EGLZ-2009798-Prumnopitys_andina

YAVKCNPEPVLLWALATLGAGFDCASRAEIEAVLGIGVTPDRIIYANPCKAETQLKYAAK

VGVNLTTFDSTEEVDKVKNAHPRCSLVLRVRAPEDCLGPKYGAPEEVNGLLQAAQRAGLN

VAGVSFHVGSGAANARVYNGAIAAVKGVFQAAARLGLFRALESYFPSVSVIGEPGRYFAE

SAFTLATNVIGKRLREYWINDGIYGSMNCLLYDHAVISALPLYRS

>H_5_ETCJ-2010524-Pilgerodendron_uviferum

YAVKCNPNPILLNSLAALGAGFDCASRAEIEAVLSLGVSADRIVYANPCKAETQLKYAAK

VGVNLTTFDSTEEVEKIRNAHPRCEVILRVKAQEDCLGSKYGAAEEIAPLLQAAQRAGLD

VAGVSFHVGSGAEHARAYTAAINAVKNTFETASKLGLLRALNAYFSTISVIAEPGRYFAE

SAFSLATNIIGKRVREYWINDGIYGSMNCLLYDHAVITAIPLFRS

>H_5_FHST-2005753-Taxodium_distichum

YAVKCNPEPVLLSSLATLGAGFDCASRAEIEAVLSLGVSPDRIVYANPCKAETQLKYAAK

VGVNLTTFDSKEEVEKIRSSHPSCEVLLRVKGQEDCLGSKYGAAEEVRPLLQAAQRADLT

VAGVSFHLGSGAEHARAYTAAISAVKYVFETASSLGLLRALNAYFSSISVIAEPGRYFAE

SAFSLATNIIGKRLREYWINDGIYGSMNCLIYDHAVITALPLYRS

>H_5_GKCZ-2016313-Diselma_archeri

YAVKCNPDPVLLNSLATLGAGFDCASRAEIDAVLSLGVPAGQIVYANPCKAETQLRYAAK

VGVNLTTFDSAEEVEKIRTAHPRCEVILRVKAQEDCLGSKYGAAEEIGPLLQAAQRAGLT

VVGVSFHVGSGAEHARAYTAAINAVKNTFETASKLGLLRALNAYFSQISVIAEPGRYFAE

SAFSLATNIIGKRVREYWINDGIYGSMNCLLYDHALITAIPLFRS

>H-5_IOVS-2056205-Pseudotsuga_menziesii

YAVKCNPDPILLSALATLGSGFDCASRAEIEAILKLGVSPDRIVYANPCKAETQLKFAAN

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VGVNLTTFDSVEEVEKIKKFHPRCVLLLRVKVPEECLGPKYGAPEEVGPLLQAAQLSGLT

VAGVSFHAGSGVARSRVYAGAVGAVRGIFDSASRLGLLRALKTYFTAVSVIAEPGRYFAE

SAFSLATNVIGKRLREYWINDGIYGSMNCLLYDHAVITALPLYRS

>K_5_JBND-2071105-Pinus_ponderosa

YAVKCNPEPALLSALATLGSGFDCASRVEIEAILKLGVSPDRIVYANPCKAVTHLKYAAS

VGVNLTTFDSIQEVEKIKKFHPRCALLLRVKIPNEILGRKYGAPEEVEPLLQAAQGSGLA

VHGVSFHVGSSVSRSGIYASAIATVRDVFDSASRLGMLSCLKTYFPKIFAMGEPGRYFAA

SAFWLASCVIGKRVREYWINDGIHGSMSCLIHDKAVITAFPLYPS

>H_5_MHGD-2013075-Microcachrys_tetragona

YAVKCNPEPALLSALATLGAGFDCASRGEIEAVLGLGVSPDRIIYANPCKAETQLRYAAK

VGVNMTTFDSTDEVDKIKKSHPRCSLVLRVRAPEDCLGPKYGAPEEVTPLLQAAKRAGLA

VAGVSFHVGSGAGNARVYTGAIASVKEVFEAAARLGLLRALDSYFPSVSVIGEPGRYFAE

LAFTLATNVIGKRLREYWINDGIYGSMNCLLYDHAVIGALPLYRS

>H_5_QSNJ-2066599-Taiwania_cryptomerioides

YAVKCNPEPVLLSALATLGAGFDCASQAEIEAVLSLGVAADRIVYANPCKAETQLKYAAK

VGVNLTTFDSKEEVEKIKSSHPRCEVLLRVKAQEDCLGSKYGAPEEIGPLLQAAHRAGLT

VSGVSFHVGSGAEHARAYTGTIGTVRSAFETAQRLGLLRALNSYFPSLSLIAEPGRYFAG

SAFSLATNIIGKRVREYWINDGIYGSMNCLLYDHAVITALPLYRS

>H_5_VGSX-2010878-Retrophyllum_minus

YAVKCNPEPALLWTLATLGAGFDCASRVEIEAVLGLGVSPDRIIYANPCKAETQLRYAAK

VGVNITTFDSTEEVDKIKKCHPRCSLVLRVRAPEDCLGPKYGAPEEIIPLLQAAKRAGLS

VTGVSFHVGSGASNARVYNGAIKAVKGVFEAAARMGLLRALQSYFPSVSVIGEPGRYFAE

SAFTLATNVIGKRLREYWINDGIYGSMNCLVYDHAVIAALPLYRS

>H_5_YYPE-2069763-Austrocedrus_chilensis

YAVKCNPDPILLNSLATLGAGFDCASRAEIEAVLSLGVSADRIVYANPCKAETQLKYAAK

VGVNLTTFDSTEEVEKISNAHPRCEVILRVKAQEDCLGSKYGAAEEIGPLLQAAQRAGLT

VAGVSFHVGSGAEHARAYTGAINAVKNAFETASKLGLLKALNAYFSTISVIAEPGRYFAE

SAFSLATNIIGKRVREYWINDGIYGSMNCLLYDHAVITAIPLFRS

>H_7_AIOU-2069900-Brugmansia_sanguinea

YAVKCNPEPSFLSMLSAMGSNFDCASRAEIEYVLSLGISPDRIVFANPCKPEADIIFAAK

VGVNLTTFDSEDEVYKIRKHHPKCELLLRIKPMDDCMGPKYGAPDEVEPLLRTAQAARLT

VSGVSFHIGSGDADSKAYLGAIAAAKGVFETAARFGMMTALEQHFHELTIIAEPGRFFAE

TAFTLATTIIGKRLKEYWINDGLYGSMNCVLYDHATVNATPLFPS

>H_7_DLJZ-2056606-Solanum_ptychanthum

YAVKCNPEPSFLSMLSAMGSNFDCASRAEIEYVLSLGISPDRIIFANPCKPESDIIFAEK

VGVNLTTYDSEEEVYKIRKHHPKCELLLRIKPMNDCMGPKYGAPEEIEPLLRTAQAARLT

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VSGVSFHIGSGDADSTAYLGAIAAAKQVFETANQLGMMTALETHFQELTIIAEPGRFFAE

TAFTLATTIIGKRLKEYWINDGLYGSMNCVLYDHATVTATPLFPS

>H_7_EMBR-2057952-Ipomoea_pubescens

YAVKCNPEPSFLTVLAAMDCNFDCASRSEIDYVLSLGVSPDRIVFANPCKPEADVVYAAN

VGVNITTFDSEYEVEKIKRFHPTCDLFLRIKPVRDCMGPKYGAPEEVEPLLLAARAARLN

VTGVSFHIGSGDAEAGAYRGAIAAARAVFDTATRLGLLQSVQEFFGGLTIIAEPGRFFAE

TPFTLAATVIGKRLREYWINDGLYGSMNCILYDHATVIATPLFAS

>H_7_GHLP-2057325-Solanum_dulcamara

YAVKCNPEPSFLSMLSAMGSNFDCASRAEIEYVLSLGISPDRIVFANPCKPESDIIFAEK

VGVNLTTYDSEEEVYKIRKHHPKCEVLLRIKPMNDCMGPKYGAPEEIEPLLRTAQAARLT

VSGVSFHIGSGDADSNAYVGAIAAAKQVFETANQLGMMTALEQHFLELTIIAEPGRFFAE

TAFTLATTVIGKRLKEYWINDGLYGSMNCVLYDHAAVTATPLFPS

>H_7_JNVS-2050848-Datura_metel

YAVKCNPEPSFLSMLSAMGSNFDCASRAEIEYVLSLGISPDRIVFANPCKPEADIIFAAE

VGVNLTTFDSEDEVYKIRKHHPKCELLLRIKPMDDCMGPKYGAPDEIETLLRTAQAARLN

VSGVSFHIGSGDADSKAYLGAIAAAKGVFETAARFGMMTALEQHFHELTIIAEPGRFFAE

TAFTLATTIIGKRLKEYWINDGLYGSMNCVLYDHATVNATPLFPS

>H_7_LQJY-2080087-Solanum_xanthocarpum

YAVKCNPEPSFLSMLSAMGSNFDCASRAEIEYVLALGISPDRIVFANPCKPESDIIFAEK

VGVNLTTYDSEDEVYKIRKHHPKCELLLRIKPMNDCMGPKYGAPEEIEPLLRIAQAARLT

VSGVSFHIGSGDADSTAYLGAIAAAKQVFETAAQLGMMTALETHFQDLTIIAEPGRFFAE

TAFTLATTIIGKRLREYWINDGLYGSMNCVLYDHATVTATPLFPS

>H_7_LWCK-2013819-Lycium_barbarum

YAVKCNPEPSFLSMLSALGSNFDCASRAEIEYVLSLGISPDRIVFANPCKPESDIIFAAK

VGVNLTTYDSEDEVYKIRKHHPKSELLLRIKPMDDCMGPKYGAPEEVEPLLRAAQAARLT

VSGVSFHIGSGDADSNAYLGAIAAAKKVFATAAEFGMMAALSQHFNELTIIAEPGRFFAE

TAFTLATTIIGKRLREYWINDGLYGSMNCVLYDHATVTATPLFPS

>H_7_MKZR-2110363-Nicotiana_sylvestris

YAVKCNPEPSFLSILSAMGSNFDCASRAEIEYVLSLGISPDRIVFANPCKPESDIIFAAK

VGVNLTTYDSEDEVYKIRKHHPKSELLLRIKPMLDCMGPKYGAPEEVDPLLRAAQAARLT

VSGVSFHIGSGDADSNAYLGAIAAAKEVFETAAKLGMMTALKQHFDELTIIAEPGRFFAE

TAFTLATTIIGKRLREYWINDGLYGSMNCVLYDHATVNATPLFPT

>H_7_NAUM-2054533-Ipomoea_lindheimeri

YAVKCNPEPSFLTVLAAMDCNFDCASRSEIDYVLALGVSPDRIVFANPCKPEADVVYAAN

VGVNITTFDSEYEVEKIKRFHPTCDLLLRIKPVHDCMGPKYGAPEEVEPLLLAARAARLN

VTGVSFHIGSGDADAGAYRGAIAAARAVFDTATRLGLLQSVQEFFGGLTIIAEPGRFFAE

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TPFTLAATVIGKRLREYWINDGLYGSMNCILYDHATVTATPLFTS

>H_7_NMDZ-2096881-Solanum_sisymbriifolium

YAVKCNPEPSFLSMLSAMGSNFDCASRAEIEYVLSLGISPDRIVFANPCKPESDIIFAEK

VGVNLTTYDSEDEVYKIRKHHPKCELLLRIKPMNDCMGPKYGAPEEIEPLLRTAQAARLT

VSGVSFHIGSGDADSTAYLGAIAAAKQVFETAAQLGMMTALETHFQDLTIIAEPGRFFAE

TAFTLATTIIGKRLREYWINDGLYGSMNCVLYDHATVTATPLFPS

>H_7_OSMU-2080375-Lycium_sp.

YAVKCNPEPSFLSMLSALGSNFDCASRAEIEYVLSLGISPDRIVFANPCKPESDIVFAAK

VGVNLTTYDSEDEIYKIRKHHPKSELLLRIKPMDDCMGPKYGAPEEVEPLLRAAHAARLT

VSGVSFHIGSGDADSNAYLGAIAAAKKVFATAAEFGMMTALSQHFNELTIIAEPGRFFAE

TAFTLATTIIGKRLREYWINDGLYGSMNCVLYDHATVTATPLFPS

>H_7_QAUE-2025470-Actinidia_chinensis

YAVKCNPEPAFLGAMAALGAGFDCASQVEIETILSLGVSPDRIIYANPCKAESHIKYAAS

VGVNLTTFDSKEEVEKIRKYHPKCALLIRIKVDDNWLGGKFGAPEEFEPLLLAARIAELA

VCGVSFHVGSIVTDSCTYRAAIAAAKTVFDMAIRLGMLRALQEYFQGLTIIAEPGRFFAE

TPFTLVATIIGKRLREYWINDGVYGSLNYLLFDHASVDLMPLYVS

>H_7_UGJI-2022873-Lycopersicon_cheesmanii

YAVKCNPEPSFLSMLSAMGSNFDCASRAEIEYVLSLGISPDRIVFANPCKPESDIIFAEK

VGVNLTTYDSEDEVYKIRKHHPKCELLLRIKPMNDCMGPKYGAPEEIEPLLRTAQAARLT

VSGVSFHIGSGDADSSAYLGAIAAAKQVFETAAQLGMMTALETHFQDLTIIAEPGRFFAE

TAFTLATTIIGKRLREYWINDGLYGSMNCVLYDHATVTTTPLFPS

>H_7_UGJI-2022874-Lycopersicon_cheesmanii

YAVKCNPEPSFLSMLSAMGSNFDCASRAEIEYVLSLGISPDRIVFANPCKPESDIIFAEK

VGVNLTTYDSEDEVYKIRKHHPKCELLLRIKPMNDCMGPKYGAPEEIEPLLRTAQAARLT

VSGVSFHIGSGDADSSAYLGAIAAAKQVFETAAQLGMMTALETHFQDLTIIAEPGRFFAE

TAFTLATTIIGKRLREYWINDGLYGSMNCVLYDHATVTTTPLFPS

>F_8_PEZP-2069738-Glycyrrhiza_glabra

YAVKCNPNPSIIGTLAALGSSFDCASRNEIETVLSLGVSPDRIIYANPCKSESHIRYAAS

VGVNVTTYDSVEEIEKIRKWHPQCELLLRIKPAGDTLGLKYGAQEEVPELLRAADVAGLK

VTGVSFHIGSGGGDTRAYHGAIAMAKGVFETASRLGMMHAIKSHFGDLVVIGEPGRYFAE

TAFTLVTRVIGKRMREYWIDDGVYGTLNCIMFDFATVTCTPLYPS

>H_8_AEPI-2051648-Linum_leonii

YAVKCNPDKALLGTLAHLGASFDCASRAEIESVLAVGVSPDKIVFANPCKPESHIKYAAA

AGVNLTTFDSVDELEKLSRLHPKCALLIRIKPPEDCLGPKYGAEDEIEPLLISAQDLRLP

VVGASFHIGSGATESGAYRGAIAAARSVFDTATRLGLMNALNDYFSGLKVISEPGRFLSE

SAFTLAATIIGKREREYWINDGLYGSMNCILYDHATVRCAPLYSS

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>H_8_AXAF-2064431-Thladiantha_villosula

YAVKCNPQPALLGTMAALGSNFDCASRAEIQAVLALGVSPDRIVFANPCKPESHIKYAAS

VGVNLTTFDSVEEVDKIRRCHPDSALLLRIKGSDDCLGNKYGAPEEIIPLLEAAKAAELS

VTGVSFHIGSGATQTGAYWATIAAAKGVFETAVKLGMMNALQKYFPNLNIISEPGRFFAE

SAFTLAANIIGKRLREYWINDGLYGSMNCILYDHATVTCTPMYSS

>H_8_SFZX-2041247-Cannabis_sativa-stem_peel

YAVKCNPDQALLGAMAALGSGFDCASRAEIQTVLGLGVSPAQIVFANPCKPEAHIKYAAT

VGVNLTTFDSKDEVEKIRKWHPKCGLLIRIKAPDDCLGPKYGAPDEVEPLLRAAQAAGLT

VCGVSFHIGSGDTHSGAYRGAIEAAKTVFETAARLGFMKALRTYFPGLSIIAEPGRFFGE

TAFTLAANVIGKRLREYWINDGIYGSMNCLLYDHATLTCVPLYDS

>H_8_BHYC-2052920-Linum_lewisii

YAVKCNPDKALLGTLAHLGASFDCASRAEIESVLAVGVSPDKIVFANPCKPESHIKYAAA

AGVNLTTFDSVDELEKLSRLHPKCALLIRIKPPEDCLGPKYGAEDEIEPLLISAQDLRLP

VVGASFHIGSGATESGAYRGAIAAARSVFDTATRLGLMNALNDYFSGLKVISEPGRFLSE

SAFTLAATIIGKREREYWINDGLYGSMNCILYDHATVRCAPLYSS

>H_8_PMRP-2040020-Cannabis_sativa-stem

YAVKCNPDQALLGAMAALGSGFDCASRAEIQTVLGLGVSPAQIVFANPCKPEAHIKYAAT

VGVNLTTFDSKDEVEKIRKWHPKCGLLIRIKAPDDCLGPKYGAPDEVEPLLRAAQAAGLT

VCGVSFHIGSGDTHSGAYRGAIEAAKTVFETAARLGFMKALRTYFPGLSIIAEPGRFFGE

TAFTLAANVIGKRLREYWINDGIYGSMNCLLYDHATLTCVPLYDS

>H_8_HNCF-2007775-Linum_hirsutum

YAVKCNPEKALLGTLAHLGASFDCASRAEIESVLSVGVSPDKIVFANPCKPESHIAYAAA

AGVNLTTFDSVDELEKMSRLHPDCALLIRFKPPEGCLGPKYGADDEIESLLTTAQSLRLS

VVGASFHIGSGATESGAYRGAIAAARSVFDAASRLGLMQALDDYFPGLIVIGEPGRFFAE

SACTLAAAIIGKRQREYWINDGLYGSMNCILYDHATIRCAPLYSS

>H_8_DGNP-2037820-Cannabis_sativa-core

YAVKCNPDQALLGAMAALGSGFDCASRAEIQTVLGLGVSPAQIVFANPCKPEAHIKYAAT

VGVNLTTFDSKDEVEKIRKWHPKCGLLIRIKAPDDCLGPKYGAPDEVEPLLRAAQAAGLT

VCGVSFHIGSGDTHSGAYRGAIEAAKTVFETAARLGFMKALRTYFPGLSIIAEPGRFFGE

TAFTLAANVIGKRLREYWINDGIYGSMNCLLYDHATLTCVPLYDS

>H_8_RPPC-2071550-Erythroxylum_coca

YAVKCNPEPALLGSLAAMGANFDCASRAEIEAVLSLGVSPDRIVYANPCKQESHIKYAAS

VGVNLTTFDSKDELEKMRKWHPKCALLLRVKAPEDCLGPKYGAPEEVIPLLQAAQAARLS

VVGASFHIGSGATHFSSYRGAIVEAKKAFETAVKMGMMTALQTYFPGLTIISEPGRFFAE

STFTLATNVIGRRLREYWINDGIYGSMNCILYDHATVTCKPLYNS

>H_8_MYVH-2061705-Linum_grandiflorum

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YAVKCNPEKALLGTLAHLGASFDCASRAEIESVLSVGVSPDKIVFANPCKPESHIQYAAA

VGVNLTTFDSVDELEKLSRLHPKCALLIRIKPPEDCLGPKYGADEEIEPLLVTAQSLRLP

VVGVSFHIGSGATESGAYQGAIAAARSVFDTAIRLGLMHALDDYFSGLKVISEPGRFFSE

TAFTLAATIIGKRQREYWINDGLYGSMNCILYDHATVRCAPLYSS

>H_9_KAWQ-2055741-Stangeria_eriopus

YAVKCNPEPAFLGALSAMGAGFDCASRAEIEAVLSLGVSADRIVYANPCKAESQLRYAAR

VGVNMTTFDSREEVDKISKCHPRCALLLRVRALQECLGPKYGAPEEVSGLLQSAHQAGLA

VAGVSFHVGSGVSQSVAYENAIAAVRGVVEAASRLGLLRSLQTYFPGVRVMAEPGRYFAE

SAFWLATTVIGKRVREYWINDGIYGSMNCLLYDHALITALPLFPS

>H_9_GNQG-2085630-Encephalartos_barteri

YAVKCNPEPAFLGALSALGAGFDCASRAEIEVVLSLGVSADRIVYANPCKAETQLKYAAR

VGVNMTTFDSKEEVEKIKKSHPRCVLLLRERALEECLGPKYGAPDEVSGLLRCAQQAGLT

VAGVSFHVGSGVAVASAYDSAIAAVRGVFDTASRLGLLRSLETYFPDVSVMAEPGRYFAE

SAFSLATNVIGKRVREYWINDGIYGSMNCLVYDHALISALPLFRS

>H_10_ALVQ-2022897-Tmesipteris_parva

YAVKCNYDGALLAVLAALGVGFDVASKSEIEMVRKLGVSHDRIIFANPCKLPSHIATASK

YGIHLTTFDSKMELLKLEKCNPQAELVLRIRVCDACLGVKYGAMDECEPLLIAAQHFGLQ

VVGVSFHVGSGALDAAPFAIAIKQARRVFDMASTLGLFRALDEYFPSVTIIAEPGRFFAE

EPFTLVTQIFGSRMAEYWVNDGIYGSMNCIFYDHATLTVRAICKA

>H_10_EEAQ-2089752-Sceptridium_dissectum

YAVKCNSDGVLLALLAALGAGFDVASKMELDTVRSLGVSGDRIIFANPCKLPSHIADAAK

HNVFLTTFDSEIELFKLRKFNPKAEVVVRIRVCDPCLGIKYGAIDECGNLLEAARKLGFQ

VVGVSFHVGSGASDPSSFTEGILQARKVFDIAATLGLLRALERYFPTVTIIAEPGRFFAE

EPFTLAAQVFGSREAEYWVNDGIYGSMNCLLYDHATLSVRALCQS

>H_10_QVMR-2007066-Psilotum_nudum

YAVKCNDDGALLAVLAALGAGFDVASKSEIESVRRLGVSHDRIIFANPCKLPSHIATASK

YGIHLTTFDSKTELLKLEKCNPQAKLVLRIRVCDACLGVKYGAMDECEPLLTAAQNFGLQ

VVGVSFHVGSGALDAAPFAIAIKQARRVFDMASTLGLLRALDEYFPSVTIIAEPGRFFAE

EPFTLATQIFGSRMAEYWVNDGIYGSMNCLFYDHATLTVRAICKA

>H_12_BMRX-2025862-Papaver_somniferum-leaf

YAVKCNPEPALLGTLALLGANFDCASKGEIETVLALGVSPDRIVYANPCKSESHIKYAAT

VGVNLTTFDSIDEVEKMRKFHPKCGLLMRIKAPEDCLGDKYGAPEEFVPLLEAANAANLV

VHGVSFHVGSGATHSRAYRAAIAEAKAIFNTAEKLGIMHALETYFPELMLISEPGRFFAE

TAFTLVTDIIGKRLREYYISDGIYGSMNCLLYDHATVTAKPLYTS

>H_12_SMZF-2012966-Argemone_mexicana-root

YAVKCNPEPALLGTLALLGADFDCASKPEIEAVLSLGVSPDRIVYANPCKSESHIKFAAS

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VGVNLTTFDSLEEIEKIRKFHPKCALLLRIKAPDDCLGQKYGAPEEVIPLLKSANAAKLS

VHGVSFHVGSGATHSRAYGGAIAEAKSVFDTAIELGMMHALETHFPGLMFISEPGRFFAE

TAFTLVTDIIGKRLREYYISDGIYGSMNCLLYDHATITAKPLYTS

>H_12_UDHA-2027520-Ceratocapnos_vesicaria

YAVKCNPDPSLLGTLAVLGANFDCASKAEIEVVLSLGVSPDRIVYANPCKAESHIRYAAQ

VGVNLTTFDSQEEVEKIRSLHPKCALLLRIKAPEDCLGSKYGAPEEVIPLLQAADAAKLA

VIGVSFHVGSGATHSRAYCGAIETAKEVFDTALRLNMMHALQAYFPGLSFISEPGRFFAE

TAFTLATNIIGRRLREYWINDGIYGSMNCVLYDHATVTSTPLYPS

>H_12_ZGQD-2011518-Corydalis_linstowiana

YAVKCNPDPSLLGTLAVLGANFDCASKAEIEAVLSLGVSPDRIVYANPCKSEPHIRYAAQ

VGVNLTTFDSQGEIEKIRRLHPKCALLLRIKAPEDCLGPKYGAPEEVTPLLQAADEAKLA

VVGVSFHVGSGATRSRAYFGAIETAKEVFDTALRLNMMHALQAYFPGLTFISEPGRFFAE

TSFTLATNIIGKRLREYWINDGIYGSMNCILYDHATVTATPLYPS

>H_13_AZZW-2001527-Chlorokybus_atmophyticus

YAVKCNPDNALLAVLAAQGAGFDVASKAELCKVMQLGVTSDRIVFSNPCKLPAHIAHAAA

AGVHLMSFDAESELHKVKVSDPNARMLLRIRADDKCLGVKYGALAEVEHLLRTAQHLGVR

VEGVDFHVGSGASDPGAFSAAIEAARHVFELAEQLGLMTALDLHFPSVRVIAEPGRFFAE

SAAALASNIFGTRNQEYWISDGLYGSMNCLLYDHATLFVRPLYRS

>H_13_FQLP-2008974-Klebsormidium_subtile

YAVKCNGDPALLSVLAALGSGFDCASLAEMQAVAAAGVAPERIIYANPCKLESHLRHAVS

AGVNLTVFDAEDELYKIKKVHPGTELLLRIRADDVCLGSKYGAFDECEPLLRAAKRLGLK

CVGVSFHVGSGAASAQSFVEAIKAAKAVFEMAEALGMMSALEKFFPEVKVIAEPGRYFAE

APAPLAALVFGRRRNEYYINDGVYGSMNCLLYDHATISARPLYRS

>H_13_KYIO-2004640-Mesostigma_viride

YAVKCNPDAALVATLASQGAGFDCASLAEMKQVLSTGVPPSLIIFANPCKMVSHIAFARD

HGVQYMTFDSVCELKKVKAIHPTAKMVLRIRADDRCLGVKYGADDEHERLLQACLDLDVD

IVGISFHVGSGSCNADAFLHAIRKARHTFDLAERLGLMTAIDEYFPAVRLIAEPGRFFAE

SSSHLACNVFGRRSHEYWVSDGMYGSMNCVMYDHSTLFARPIHLS

>H_13_HAOX-2004748-Spirogyra_sp.

YAVKCNPEPVLLSLLASLGAGFDVASKSEIEAVQPHGVSPDRMIFANPCKLPSHMKFASS

NNVSLTTFDSESELVKFKNFYPGVNAVLRLRADDRCLGVKYGAFEDCQRLILLAKDMGIN

VAGVAFHVGSGASDPESYVDGILAARSLFDMAVSYGMMWALDRYFPDVSIIGEPGRFFAE

APFTLATHVFGTRSPEYWINDGLYGSMNCLLYDHAELTVRPLYKS

>H_13_WDCW-2048528-Mesotaenium_endlicherianum

YAVKCNPDPALLSLLAALGAGFDVASKSEITAVVTRGVSSERMIYANPCKLPSHITAAAK

DGVLRTTFDSESELVKLKKYHPGAHAVLRLRADDRCLGVKYGALEECEHLLKVAQSLGIH

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VAGVAFHVGSGAADSQSYTDGIETVRSLFDMAEALGMMTALDEYFPSVQIIGEPGRFFAE

APSTLATHVFGTRGAEYWINDGIYGSMNCLLYDHAELTARPLLPS

>H_13_BFIK-2030785-Entransia_fimbriat

YAVKCNPNPGLLRIMASLGAGFDCASKAEIDMVQELGVCGSQIIYANPCKLPSHIRHASI

CGVDLTVFDSEDELHKLKKLHPLTRLLLRIRADDQCLGVKYGALEECMHLLQVAHSLGLS

CVGVSFHVGSGASDARSFMRAIESARGVFDMAEGLGMMTALARFFPEVSVIAEPGRYFAE

ATSTLATLVFGRRPNEYYVNDGVYGSMNCILYDHAKVTARTLYLS

>H_13_ZRMT-2009586-Mougeotia_sp.

YAVKCNPDAALLSLLGALGSGFDVASKAEIEAVLSLGIESDRMIFANPCKLPSHIRFAGQ

EGVNYTTFDSESELIKLKKLNPSAKAVIRLRADDRCLGVKYGAFEDCRELLMAAKRLQVE

VAGVAFHVGSGASDPCSFADGIEAAKALFDMAEELGMMNALDIHFPYVRIIGEPGRFFAE

APSTLATHVFGTRGSEYWINDGLYGSMNCLLYDHAELTTRPLYKS

>H_13_JOJQ-2001281-Cylindrocystis_cushleckae

YAVKCNPDRALLTLLASLGTGFDVASKAELEAVVELGVSPDRIIYANPCKLPGHIAAAAR

EGVHYTTFDSESELQKLKKINPNAQAVLRLRADDRCLGVKYGALEDCEELLLAAKKLGVN

VAGIAFHVGSGAADPASYADGISAARSLFTLAENLGMMKALDEHFPSVRIIGEPGRFFAE

APATLATHVFGTRGCEYWINDGLYGSMNCLLYDHAELTTRPLYQS

>H_14_FANS-2000389-Leiosporoceros_dussii

YAVKCNPEPVLLSLLASLGAGFDVASKSEIEAVQPHGISPDRMIFANPCKLPSHMKFASS

NNVSLTTFDSESELVKFKNFYPGVNAVLRLRADDRCLGVKYGAFEDCQRLILLAKDMGIN

VAGVAFHVGSGASDPESYVDGILAARSLFDMAVSYGMMWALDRYFPDVSIIGEPGRFFAE

APFTLATHVFGTRSPEYWINDGLYGSMNCLLYDHAELTVRPLYKS

>H_14_IQJU-2003727-Anthoceros_formosae

YAVKCNPEPVLLSLLASLGAGFDVASKSEIEAVQPHGISPDRMIFANPCKLPSHMKFASS

NNVSLTTFDSESELVKFKNFYPGVNAVLRLRADDRCLGVKYGAFEDCQRLILLAKDMGIN

VAGVAFHVGSGASDPESYVDGILAARSLFDMAVSYGMMWALDRYFPDVSIIGEPGRFFAE

APFTLATHVFGTRSPEYWINDGLYGSMNCLLYDHAELTVRPLYKS

>H_15_BMJR-2000153-Adiantum_tenerum

YAVKCNSDVSFLALLSSLGAGFDVASKAELDLVRSLGVGGDRIIFANPCKLPSHILHAAN

SDVHLTTFDSEGELFKLHKLNPQAEVVLRIRVCDACLGVKYGAMEDCESLLHVAKNLGLK

VVGIAFHVGSGASDPSSFVQGIAEARHLFDVAKVMGLLRAIDKFFPSVTIIAEPGRFFAE

ESFTLAAQIFGSRDSEYWINDGIYGSMNCLLYDHATLSVHGLCQS

>H_15_CJNT-2004570-Polypodium_glycyrrhiza

YAVKCNSDRMILAILAALGAGFDVASKVELDMVRDLGVGGDRIIFANPCKLPSHIQHARN

HDVHLTTFDSESELYKLHRMNPRAEAVLRIRVCDACLGVKYGAMSECESLLLVAKGLGLT

VVGVAFHVGSGASDPSSFAQGIYQARQVFEMARSMGTFRALDRYFPCITVIAEPGRFFAE

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EIFTLASQVFGSRNVEYWINDGIYGSMNCLLYDHATLSVRALSDS

>H_15_CQPW-2004067-Anemia_tomentosa

YAVKCNSDGVLLALLSALGAGFDVASKAELDMVSYLGVGNDRVIFANPCKLPSHIGYAAS

HNIHLTTFDSEVELYKLQKMNPKAEVVLRIRVCDPCLGVKYGAMEECRSLLMVARNVGLE

VAGVAFHVGSGASDPSSFAKGITQAREVFDMATSMGILRALETFFPSVTVIAEPGRFFAE

ESFTLAAQIFGSRDVEYWINDGIYGSMNCLLYDHAIISVRALRQS

>H_15_DCDT-2016720-Cheilanthes_arizonica

YAVKCNSDVPLLALLSTLGSGFDVASKAELDLVRSLGIGGDRIIFANPCKLPSHITHAAN

HDVHLTTFDSEGELYKLHKMNPQAEVVLRIRVCDACLGVKYGAMEDCENLLYVAKNLGLK

VVGIAFHVGSGASDPSSFAQGIGQARLLFDMAKAMGILRALEKFFPSVTVIAEPGRFFAE

ESFTLAAQVFGSRNAEYWINDGIYGSMNCLLYDHATLSVRALCQS

>H_15_EWXK-2122583-Thyrsopteris_elegans

YAVKCNGDGMLLALLAALGAGFDVASKAELDTVQNLGVGGDRIFFSNPCKLPSHVTYAAA

RDVHLTTFDSEAELYKIWKLNPQAEVVLRIHICDVCLGVKYGASEECEGLLSLAKYLGLQ

VVGVAFHVEGGASDPMSFANGIAHARKVFDLARFLRILRALEKYFPSVTVIAETGRFFAE

GAFTLAAQVFGSCNAEYWINDGIYGSMICLLYDHAIISVRALFES

>H_15_FCHS-2004087-Deparia_lobato-crenata

YAVKCNSDRMLLAILVALGAGFDVASKLELDIVRDLGVGGDRIIFANPCKLPSHIQHARN

HDVHLTTFDSETELHKLHKMNPRAEAVLRIRVCDACLGVKYGAMNECESLLLVAKGLGLT

VVGVAFHVGSGASDPSSFAQGIAQARQVFDMAKAMGMLRALDRYFPCITVIAEPGRFFAE

ETFTLASQVFGIRNVEYWINDGIYGSMNCLLYDHATLSVRALSES

>H_15_FLTD-2016082-Pteris_ensigormis

YAVKCNSDVLLLALLSSLGAGFDVASKAELDLVRSLGVGGDRIIFANPCKLPSHVLHAAN

YDVHLTTFDSEGELYKLHKLNPQAEVVLRMRVCDPCLGVKFGAMEDCESLLHVAKNLGLK

VVGIAFHVGSGASDPSSFAHGIAQARLLFDTAKKIGLLRALEKFFPSVTVIAEPGRFFAE

ESFTLAAQVFGSRDVEYWINDGIYGSMNCVFYDHAVLSVRWLCQS

>H_15_GSXD-2016209-Myriopteris_eatonii

YAVKCNSDVPLLALLSTLGAGFDVASKAELDLVNSLGVGGDRIIFANPCKLPSHIVHAAN

HGVHLTTFDSEGELYKLHKLNPQAEVVLRIRVCDACLGVKYGAMEDCENLLYVAKNLGLK

VIGVAFHVGSGASDPSSFAHGISQARLLFDMAKAMGILRALEKFFPSVTVIAEPGRFFAE

ESFILAAQVFGSRDAEYWINDGIYGSMNCLLYDHATLSVRALCSS

>H_15_HEGQ-2003697-Gymnocarpium_dryopteris

YAVKCNSDRVLLAILAALGAGFDVASKAELDILRNLGVGGDRIIFANPCKLPSHIQHARN

HNVHLTTFDSETELYKLHKMNPKAEAVLRIRVCDACLGVKYGAMNELESLLLVANGLGLT

VVGVAFHVGSGASDPSSFAQGIAQARQVFDMAKAMGMLRALDRYFPCITVIAEPGRFFAE

ETFTLASQVFGSRNVEYWINDGIYGSMNCLLYDHATLTVRALSES

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>H_15_KJZG-2012896-Asplenium_platyneuron

YAVKCNSDRVLLAVLAALGAGFDVASKLELDMVKDLGVGGDRIIFANPCKLPSHIQHARN

HGVHLTTFDSETELYKLHKLNPEAEAVLRIRVSDPCLGVKYGALSECENLLLVAKGLGLT

VVGVAFHVGSGASDPSSFAEGITQARQVFDIGKAMGIFRALDRYFPCITVIAEPGRFFAE

ETFTLASQVFGCRNVEYWINDGIYGSMNCLLYDHATLSVRALSES

>H_15_LHLE-2015185-Cystopteris_fragilis

YAVKCNSDHVLLAILAALGAGFDVASKVELDMVRDLGVGGDRIIFANPCKLPSHIQHARN

HDVHLTTFDSETELYKLLKMNPKAEAVLRIRVCDACLGVKYGAMSECESLLLVAKSLGIT

VVGVAFHVGSGASDPSSFAQGIAQARQVFDMAKAMGTFRALDRYFPCITVIAEPGRFFAE

ETFTLASQVFGSRNVEYWINDGIYGSMNCLLYDHATLTVRALYKS

>H_15_MEKP-2006943-Dipteris_conjugata

YAVKCNADGVLLALLAALGAGFDVASKAELDMVRCLGVGGDRIIFANPCKLPSHIANAAS

SGVHLTTFDSEVELYKLRNVNPQAEVVLRIRVCDPCLGVKYGAMEECESLLMVAKNLGVQ

VVGVAFHVGSGASDPSSFAEGIAQSRKVFDMASKIGILRALEKFFPYVTVIAEPGRFFAE

GSFTLAAQVFGSRNAEYWINDGIYGSMNCLLYDHAIISVRPLCQS

>H_15_MTGC-2006101-Dennstaedtia

YAVKCNSDHVLLALLAALGAGFDVASKVELDMVRDLGVGGDRIIFANPCKLPSHIQHACN

HDIHLTTFDSETELYKLCKINPKAEAVLRIRVCDACLGVKYGAMDECESLLLVAKGLGLA

VVGVAFHVGSGASDPSSFAQGITQARQVFDMAKGMGIFRALEKFFPCITVIAEPGRFFAE

ETFTLASQVFGRRNAEYWINDGIYGSMNCLLYDHATLSVRALSES

>H_15_NOKI-2009815-Lindsaea_linearis

YAVKCNSDLPLLALLSALGAGFDVASKAELDMVRSIGVRGDRIIFANPCKLPSHISYSAK

YDVHLTTFDSEAELYKLHKVNPKAEVVLRIRVCDSCLGFKYGAMEECEGLLNVANTLGLD

VVGIAFHVGSGASDPLSFAQGIAQARQLFDMAKAMGMLRALEKYFSSITVIAEPGRFFAE

EPFTLVTQVFGSRNAEYWINDGLYGSMNCLVYDHAALSVRGLCES

>H_15_OQWW-2026291-Davallia_fejeensis

YAVKCNSDVLLLSLLSTLGAGFDIASKAELDIVRGLGVGGDRIIFANPCKMPSHILHAAN

YDVHLTTFDSEGELYKLHRLNPQAEVLLRIRVCDACLGVKYGAMEDCESLLGVAKNLGLN

VVGIAFHVGSGASNPSSFAHGIAQARVLFDIAKSLGIFRALDKYFPSLTVIAEPGRYFAE

ESFTLAAQVFGSRNAEYWINDGIYGSMNCLLYDHATLSVRALCDS

>H_15_PBUU-2001147-Lygodium_japonicum

YAVKCNADRVLLALLAALGAGFDVASKAELEIVQSLGVGGDRLIFANPCKLPSHISYAGG

RGIHLTTFDSEAELYKLRKFNPQAEVVLRIRVCDSCLGVKYGAMEECESLLLTAKILGLQ

VVGVAFHVGSGASDPLSFANGIAQARKVFDMAMLLGLLRALDKFFPSVTVLAEPGRFFAE

DSFTLAAQIFGSRNAEYWINDGIYGSMNCLLYDHAVISVRPLCHS

>H_15_POPJ-2011761-Pteris_vittata

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39

YAVKCNSDVPLLALLSVLGAGFDVASKAELDLVRSLGVGGDRIIFANPCKLPSHVVHAAN

HDVHLTTFDSEGELYKLHRFNPQAEVVLRIRVCDPCLGVKYGAMADSESLLYLAKSLGLK

VVGIAFHVGSGASDPSSFAHGIAQARLLFDTAKTMGLLRALEKFFPSVTVIAEPGRFFAE

ESFTLAAQVFGSRDAEYWINDGIYGSMNCLLYDHAVLSVRGLCQS

>H_15_QIAD-2059485-Hymenophyllum_bivalve

YAVKCNADKVLLALLAALGAGFDVASKTELDTVMKLGVGGDRIIFANPCKLPSHITYAAG

LGVHLTTFDSEVELYKVRKVNPQAEVVLRIRICDACLGAKYGAFDECESLLLVARNLGLQ

VVGVAFHVGSGASDPSSFAEGIAQARKVFDMAIKMGMLRALEKFFPCVTVIAEPGRFFAE

GSFTLAAQVFGNRNAEYWINDGIYGSMNCLLYDHAVISVRALCLS

>H_15_RFRB-2035525-Didymochlaena_truncatula

YAVKCNSDVPFLALLSSLGAGFDVASKAELDIVRGLGVGADRIIFANPCKLPAHILHATN

HDVHLTTFDSEGELYKIYKGNPQAEVVLRIRVCDPCLGVKYGAMEDCESLFGVAKNLGLK

VVGIAFHVGSGASDPLSFAHGIAQARLLFDMAKSLGIFRALDEYFPSITVIAEPGRYFAE

ESFTLATQVFGSRNAEYWINDGVYGSMNCLLYDHATLSVRALCES

>H_15_RICC-2001678-Cystopteris_reevesiana

YAVKCNSDHVLLAILAALGAGFDVASKVELDMVRDLGVGGDRVIFANPCKLPSHIQHARN

HDVHLTTFDSETELYKLLKMNPKAEAVLRIRVCDACLGVKYGAMSECESLLLVAKSLGLS

VVGVAFHVGSGASDPSSFAQGIAQARQVFDMAKAMGTFRALDRYFPCITVIAEPGRFFAE

ETFTLASQVFGSRNVEYWINDGIYGSMNCLLYDHATLTVRALCKS

>H_15_SKYV-2016271-Vittaria_lineata

YAVKCNSDASLLALLSALGAGFDVASKAELDVVRSLGIGGDRIIFANPCKLPSHILHAAD

HNVLLTTFDSEGELYKLKKLNPQAEVVLRIRVCDACLGVKYGAMEDCEKLLFLAKSLRLK

VVGIAFHVGSGASDPSSFAQGMAQARILFDKSKAIGLLRALDKFFPSVTVIAEPGRFFAE

ESFTLAAQVFGRRDAEYWINDGIYGSMNCLLYDHAILSVRPLCKS

>H_15_UWOD-2140412-Plagiogyria_japonica

YAVKCNSDRVLLALLSALGAGFDVASKAELDMVRDLGVGGDRIIFANPCKLPSHILHAAN

HDVHLTTFDSEAELYKLLKVNPQAEVVLRIRVCDECLGVKYGAMEECESLLLIAKGLGLK

VVGVSFHVGSGASDPSSFAQGISQARKVFDMAKVMEMLRALETFFPCVTVIAEPGRFFAE

ESFTLAAQVFGSRNAEYWINDGIYGSMNCLLYDHAILSVRALTES

>H_15_YCKE-2012615-Notholaena_montieliae

YAVKCNSDVPLLALLSTLGAGFDVASKAELDLVRSLGIGGDRIIFANPCKLPSHIMHAAN

HDVHLTTFDSEGELYKLQKLNPQAEVVLRIRVCDACLGVKYGAMEDCENLLYIAKNLGLK

VVGIAFHVGSGASDPSSFAHGICQARLLFDMAKVMGILRALEKFFPGVTVIAEPGRFFAE

ESFTLVAQVFGSRDAEYWINDGIYGSMNSLLYDHATLSVRALCQS

>H_15_YJJY-2078159-Woodsia_scopulina

YAVKCNSDVPLLALLSALGAGFDVASKAELDIVRGLGVGGDRMIFANPCKLPSHILHAAN

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HDVHLTTFDSEGELHKLYKVNPQAEVVLRIRVCDACLGVKYGAMEDCESLLGVAKTLGLK

VAGIAFHVGSGASDPSSFAHGIAQARALFDMARSMGIFRALDKYFPSITVIAEPGRYFAE

ESFTLAAQVFGSRNAEYWINDGIYGSMNCLLYDHATLSVRALCES

>H_15_YLJA-2073839-Polypodium_amorphum

YAVKCNSDVLLLAILSSLGAGFDIASKAELDIVRGLGVGGDRIIYANPCKLPSHILHAAN

YDVHLTTFDSEGELYKLYKLNPQAEVVLRIRVCDACLGVKYGAMEDCESLLGVAKNLGLK

VVGVAFHVGSGASDPSSFAHGIAQARVLFDMAKSVGIFRALDKYFPSITVIAEPGRFFAE

ESFTLAAQVFGSRNAEYWINDGIYGSMNCLLYDHATLSVRAVCDS

>H_16_HERT-2008826-Sphaerocarpos_texanus

YAVKCNPDVALLALLHKLGAGFDVASKAELMAVTEIGAVPDNIIFANPCKLPTHIVEAGK

FGVLRTTFDSESELFKLKKHLPHAEVVLRIRADDPCLGIKYGAMEECEQLLKVAKQLDLK

VVGVAFHVGSGASDASAFAYGIECAKQVFETAAALGLMKALEKFFPSVTIIAEPGRYFAE

DAFTLATYVFGSRGAEYWVNDGIYGSMNCLLYDHATLSVRALYQS

>H_16_JPYU-2010158-Marchantia_polymorpha

YAVKCNPDAALLALLHKLGAGFDVASKSELKAVTDIGAVPENIIFANPCKLPTHITEAGK

HGVLRTTFDSESELYKLKKFLPHAEVVLRIRADDPCLGTKYGALEECEQLLTVAKQLSLK

VVGVAFHVGSGASDASAFAYGIECAKYVFGVAEAMGLMKALDKCFPSVTVIAEPGRFFAE

DAFTLATYVFGCRGAEYWVNDGIYGSMNCLLYDHAVLSVRALYQS

>H_16_PIUF-2092589-Pellia_cf._Epiphylla

YAVKCNSDLALLSLLAKLGAGFDVASKAELGAVAGLQVSPDRMIFANPCKLPTHIVDAGN

HGVYRTTFDSESELYKLKKYLPQAEVVLRIRADDPCLGVKYGAFDECEHLLRVAKQLHLK

VVGVAFHVGSGASDASAFEYGILSARRMFDVAASLGLLNALNKHFPGVDIIAEPGRYFAE

EAFTLVTNVFGTRSAEYWVNDGIYGSMNCLLYDHATLNVRALHQT

>H_16_WJLO-2037974-Riccia_berychiana

YAVKCNPDVALLATLHKLGAGFDVASKAELKAVSDIGAAPENMIFANPCKLPTHVVEAGK

YGVLRTTFDSESELHKLKKYLPNAEVILRIKADDPCLGTKYGALDECEQLLAVVKQLSLK

VVGVAFHVGSGASDPCAFAHGIACARHVFDLAAAMGLMKALDKHFPSVSVIAEPGRFFAE

DAFTLATYVFGSRDAEYWVNDGIYGSMNCLLYDHAVLSVRALYPS

>H_16_YFGP-2012066-Pallavicinia_lyellii

YAVKCNTDATLLSLLAKAGAGFDVASKAELAVVRQVGVVPDRIIFANPCKLPSHIVDAAK

HGVRRTTFDSETELCKLSKYHPKAELVLRIRADDVWLGVKYGALDECENLLGGAKKLGLL

VVGVAFHVGSGATHAASFAQGIAFARGVFDLASALGLLKALDEHFPSVEVIAEPGRYFAE

EAFTLATHVFGSRGADYWVNDGIYGSMNCLLYDHATLSVRAVYQS

>Y_17_CBAE-2002663-Huperzia_myrisinites

YAVKCNPSPPLLSTLAALGAGFDCASKSELEQIISMGVSAQRIIFANPCKMLSHIKYASA

VGANLTTYDSENEVAKVKLHSPNAKLLLRLRADDRWLGVKYGAASEVEHLLMVAANAGVD

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VVGVSFHIGSGASDGRAYLDAISAARGVFDKALSMGLMKALHEYFPGVSVIAEPGRYFAE

APTTLAAMIYGKRVREYWINDGIYGTMNCLIHDYAVLSPRPLHTS

>Y_17_ULKT-2002309-Lycopodiella_apressa

YAVKCNPSIPLVSTLAALGAGFDCASKSELELVSSIGVSSQRIIYANPCKMTSHIAYASS

IGVNLTTYDCENEVGKVKRNNPNAQLLLRLRADDLWLGVKYGAISEVEQLLTAAASAKMH

VVGVSFHIGSGASDARSYLEAIAAARKVFDMALTLGLMHALDQYFPGVTIIAEPGRYFAE

VPTTLAAMVYGKRVREYWINDGIYGTMNCLIHDYAVLCPRPLFKS

>Y_17_ZZEI-2003348-Phylloglossum_drummondii

YAVKCNPSPPLVSTLAALGAGFDCASKSELEQIISMGVSAQRIVFANPCKMVSHIKYASS

VGVSLTTYDSEHEVAKIKLHSPNAKLLLRLRADDRWLGVKYGAPSEVDHLLEVAASAKVE

VVGVSFHIGSGASDGRAYLDAIAAARGVFDKALSMGLMRALDQYFPGVKVIAEPGRYFAE

TPTTLAAMVYGKRVREYWINDGIYGTMNCLIHDYAVLCPRPLHIS

>Y_17_GTUO-2003077-Huperzia_selago

YAVKCNPSPPLLSTLAALGAGFDCASKSEVEQIISMGVSAQRIIFANPCKMLSHIKYASS

VGVNLTTYDSEHEVAKVKLHSPNAKLLLRLRADDRWLGVKYGASSEVEHLLMVAANAKVD

VVGVSFHIGSGASDGRAYLDAIAAARGVFDKALSMGLMHALHEYFPGVSVIAEPGRYFAE

APTTLAAMIYGKRVREYWINDGIYGTMNCLIHDYAILCPRPLHTS

>Y_17_PQTO-2083290-Lycopodium_deuterodensum

YAVKCNPSPPLLSTMAALGAGFDCASKSELEQVIALGVSPRRIVFANPCKMPSHIKHASS

VGVNLTTYDCEHEVTKVKLNNPNAKLLLRLRADDPWLGVKYGATHEVEDLLMAASKAQVD

VVGVSFHIGSGASDARSYLYAIAAARKVFEKALALGLMNALDQYFPGVSIIAEPGRYFAE

VPTTLASMVYGKRLREYWINDGIYGTMNCLIHDYAVLCPRPLYKS

>Y_17_GAON-2005558-Huperzia_squarrosa

YAVKCNPSPPLLSTLAALGAGFDCESKSEVELIISMGVSEQRIIFANPCKMPSHIKYASS

VGVNLTTYDSEHEVAKVKLHSPNAKLLLRLRADDRWLGVKYGASSEVDHLMMVAAKAKLD

VVGVSFHIGSGASDGRAYADAIAAARAVFDKALSMGLMHALHEYFPGVSVIAEPGRYFAE

APTTLAAMIYGKRVREYWINDGIYGTMTCLIHDYAVLAPRPLHTS

>Y_17_UPMJ-2018782-Pseudolycopodiella_caroliniana

YAVKCNPSLPFLSTMAALGAGFDCASKSELELVLSIGVSSQRIIYANPCKMMSHIAYASS

VGVNLTTYDSENEVIKVKRNNPNAKLLLRLRADDLWLGVKYGAMSEVEQLLTAAADENMH

VVGVSFHIGSGASDARSYLEAIAAARKVFDIALTLGLLQALDQYFPGVTIIAEPGRYFAE

VPTTLAAMVYGKRVREYWINDGIYGTMNCLIHDYAVLCPRPLFKS

>H_18_FALI-2121480-Calycanthus_floridus

YAVKCNPEPAILSALAALGAGFDCASRAEIEAVLALGVSASNIVYANPCKAEAQIKYAAN

VGVNLTTFDSRDEVEKIRKWHPRCALLLRLKAPDDCLGPKYGAPEEVVPLLQAAHAARLT

VAGVSFHVGSGATHVRAYHGAIAAAKEVFNAAARLGMMHAIQAYFPGLKLMAEPGRFFAE

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TALTLATNIIGKRLREYWINDGIYGSMNCILYDHATVTAIPLYTS

>H_18_WAIL_2069374-Laurelia_sempervirens

YAVKCNPDPAFLGALAALRAGFDCASRAEIEAVLAIGVSPDQIVYANPCKAEAQIKYAGS

VGVNLTTFDSRDEIEKIRKWHPRCELLLRLKAPDDCLGPKYGAPEEVAPLLQAAQAARLN

VVGVSFHVGSGATHAQAYRGAIAAVKAVFDAASRLGMMRALQSYFPSLTLMAEPGRFFAE

TAFTLATNIIGKRLREYWINDGIYGSMNCILYDHATVTAVPLYPS

>H_18_BCGB-2010509-Cinnamomum_camphora

YAVKCNPEPAILGALAALGAGFDCASRAEIEAVMALGVPAGQIVYANPCKAEAQIKYAAG

VGVNLTTFDSREEIEKLRRWHPRCALLLRLKAPEDCLGPKYGAPEEVIPLLQAAHTARLV

VKGVSFHVGSGAMHARAYRVAIAAAKTVFDTAARLNMMHALQAYFPGLTLMAEPGRFFAE

TTFTLATNIIGKRLREYWINDGIYGSMNCILYDHATISAMPLYGS

>H_21_ZTHV-2016440-Atrichum_angustatum

YAVKCSPDPALLSTLATLGAGFDCASKAEISQVLAIGVPSERIIFANPCKMHGHIKYAAS

VGVNIMTFDCEMEVHKVKSCHPDAVLLLRIRADDRCLGVKYGAMCEVEGLLRVAHECNVP

VAGVSFHIGSGATDANSFTDAIAAAREVFDIAANLCLMDALNTYFPGVTIIAEPGRYFAE

SPSTLATMVMGKRLNEYWINDGIYGSMNCLLYDHAVLKYRPFHNS

>H-21_WOGB-2094269-Andreaea_rupestris

YAVKCSPDPALLSTLAALGAGFDCASKAEIAQVLALGVPCERVLFANPCKMPSHVTYAAS

VGVNIMTFDCESEVHKVRASHPNAVLLLRIRTDDRCLGVKYGAMSEVEPLLTVAADHGVP

VAGVSFHIGSGATDALSFTDAIAAAREVFDIAARLQLMDALEKYFPGITIIAEPGRYFAE

SPSTLATMVMSKRLKEYWINDGIYGSMNCLLYDHALLGYRPLHNS

>H_21_RCBT-2029064-Sphagnum_palustre

YAVKCSPDRALLTTLAALGAGFDCASKAEISQVLDLGVATDRIVFANPCKMQSHVAYAAS

VGVNLTTFDSESEVHKVKAHHPGAVLLLRIRTDDRCLGVKYGAMYEVEHLLRVADNLHVP

VAGVSFHIGSGATAAFSFTDAIAAAREVFDISERLGLMHALDSYFPGVKIIAEPGRYFAE

TPSTLATTVIGKRVKEYWINDGIYGSMNCLLYDHAVLKYRPLHNS

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43

Supplemental Data S3. Original amino acid alignment by using ClustalW in MEGA6 program

>Lupinus_angustifolius

------------------------------------------------------------

-----MPSLLLSEGLYQAKGATTPLSLKAIYNASGVKGKR---VTPLLANEQ--------

--EGGISHFIQSIIRNTP-------DI-DSPFLVLDLGVIMHLMEKWTTNLPTVQSYYAV

KCNPNPSLLGVLAALGSSFDCASRAEIESVLSLG-VSPDRIIYANPCKSESHIKYAATVG

VNVTTFDSKEEIHKIKKWHPKCELLIRIKPPQDSG------ARNALGLKYGA--LPEEVK

PLLQAAKDAELKVVGVSFHIGSGGAD--SRTYHGAIAAAKSVFDMASNELGMPRMKIVDI

GGGFTCG------NQFDAASFHVNEALEDNFGKEEG----VVVIGEPGRYFAESPFTLAS

KVIGKRVRGEV---------------REYWIDDGIYGSLNCIMYDFATVTCTPLACSSK-

----PEDPECK------NAKMYPS---------------------TVFGPTCDSLDTVLT

DYLLP-ELELDDWVVFPNMGAYTTSSGTNFNGFNTTAISTYLAYSTPIAMEKSMF-----

-----------------------------------

>Sophora_flavescens

------------------------------------------------------------

-----MPTLVTEA--FQAKGAG-PLSLKPPFSASGVKGKR---VTALSAKE---------

--EGGISSFIQSIIHDKP-------EM-DSPFLVLDLGVVMDLMDNWTNNLPTVQPFYAV

KCNPNPCLLGALAALGSSFDCASRAEIESVLSLG-VSPDKIIYANPCKSESHIKYAASVG

VNVTTFDSKEEIDKIRKWHPKCELLIRIKPPGDSG------ARNALGLKYGA--LPEEVM

PLLQAAQNAGLKVTGVSFHIGSGGAD--SQTYHGAIAAAKRVFDMASSELNMPRMKVLDI

GGGFTCG------KQFEAAALHVNEALQVHFGDEEG----VVVIGEPGRYFAESAFTLAS

KVIGKRVRGEV---------------REYWIDDGIYGSLNCIMFDFATVTCSPLACSSK-

----PENPRCR------DSKTYPS---------------------TVFGPTCDSLDTIFR

DYQLP-ELELNDWLVFPNMGAYTTSSGTNFNGFSTSAIATYLACSSPIGREQAMIESAVM

FANSMFSSFATPKPIV-------------------

>Echinosophora_koreensis

------------------------------------------------------------

-----MPTLVTEA--FQAKGAG-PLSLKPLFSASGVKGKR---VTALSAKE---------

--EGGISSFIQSIIHDKP-------EM-DSPFLVLDLGVVMDLMDNWTNNLPTVQPFYAV

KCNPNPCLLGALAALGSSFDCASRAEIESVLSLG-VSPDRIIYANPCKSESHIKYAASVG

VNVTTFDSKEEIEKIRKWHPKCELLIRIKPPGDSG------ARNALGLKYGA--LPEEVM

PLLQAAHNAGLKVTGVSFHIGSGGAD--SQTYHGAIAAAKRVFDMASSELNMPRMKILDI

GGGFTCG------KQFEAAALHVNEALQVHFGDEEG----VVVIGEPGRYFAESAFTLAS

KVIGKRVRGEV---------------REYWIDDGIYGSLNCIMFDFATVTCSPLACSSK-

----PENPKCR------DSKTYPS---------------------TVFGPTCDSLDTIFR

DYQLP-ELELNDWLVFPNMGAYTTSSGTNFNGFSTSAIATYLAYSSPIAREQAMIESAVM

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44

FANSMFSSFATPKP---------------------

>Cicer_arietinum

------------------------------------------------------------

-----MPTLVVEE--SH-------TNLKSIFGASGVKGKK---VTTL--PPE--------

--IT-ISHFIQSIIKNKS------SQI-DSPFSVLDLRVLMDLMTKWTTKLPTVKPYYAV

KCNPNLSLIGTLASLGSNFDCASRAEIEAVLSLG-VSPDRIIYANPCKSESHIKYAANVG

VNITTYDSVGEIDKIKKWHPKCELVLRIKPQEDSG------ARSCLGLKYGA--LVEEVP

ELLKAADVAGLKVIGVSFHIGSGGGN--AMAYHGAIALAKNVFETAS-LLGMPKMKILNI

GGGFTSG------TKFDVAALNVNDAIKTYFGNDED----LVVIGEPGRYFAETSFTLAT

KIIGKRVRGEL---------------KEYWIDDGIYGTLNNIMFDFAIVSCTPMRFSSK-

----HEKNVR-------DTKSYAS---------------------TVFGPTCDSVDTVLK

EYELP-ELEVNDWLVFQNMGAYTLSSGTNFNGFSSSAKNIYLACSTPVPREETNF-----

-----------------------------------

>Themopsis_lupinoides

------------------------------------------------------------

------------------------------------------------------------

---------------------------------------------------------YAV

KCNPNPSLLGALAALGSCFDCASRAEIESVLSLG-VKPDRIIYANPCKSESHIKYAACVG

VNVTTFDSKEEIEKIRKWHPKCELLIRIKPPQDSG------ARNALGLKYGA--LPEEVM

PLLETARDAGLKVTGVSFHIGSGGAD--SRTYHGAIEASRRIFDMASSELGMPRMKILDI

GGGFTCG------KHFESASLHVNEALEANFGNEEG----IVVIGEPGRYFAESAFILAS

KVIGKRVRGEV---------------REYWIDDGIYGSLNCIMYDFATVTCSPLACSSK-

----PENPRCR------DSKTYPS---------------------TVFGPTCDSLDTVLR

DYQLP-ELQLNDWLVFPNMGAYTTSSGTNFNGFNTSATPTYLAYTSPIAREQTML-----

-----------------------------------

>Thermopsis_chinensis

------------------------------------------------------------

------------------------------------------------------------

---------------------------------------------------------YAV

KCNPNPSLLGALAALGSSFDCASRAEIESVLSLG-VKPNRIIYANPCKSESHIKYAASVG

VSVTTFDSKEEIEKIKKWHPKCELLIRIKPPQDSG------ARNALGLKYGA--LPEEVM

PLLQAARDAGLKVTGVSFHIGSGGAD--SRTYHGAIEASRRIFDMASSELGMPRMKILDI

GGGFTCG------KHFESASLHVNEALEANFGNEEG----IVVIGEPGRYFAESAFTLAS

KVIGKRVRGEV---------------REYWIDDGIYGSLNCIMYDFATVTCSPLACSSK-

----PENPRCR------DSKTYPS---------------------TVFGPTCD-------

------------------------------------------------------------

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45

-----------------------------------

>Baptisia_australis

------------------------------------------------------------

------------------------------------------------------------

---------------------------------------------------------YAV

KCNPNPSLLGALAALGSSFDCASRAEIESVLSLG-VKPDRIIYANPCKSESHIKYAASVG

VNVTTFDSKEEIEKIRKWHPKCELLIRIKPPQDSG------ARNALGLKYGA--LPEEVM

PLLQAARDAGLKVTGVSFHIGSGGAD--SRTYHGAIETSRRIFDMASSELGMPRMKILDI

GGGFTCG------KHFESASVHVNEALEANFGNEEG----IVVVGEPGRYFAESAFTLAS

KVIGKRVRGEV---------------REYWIDDGIYGSLNCIMYDFATVTCSPLACSSK-

----PENPRCR------DSKTYPS---------------------TVFGPTCD-------

------------------------------------------------------------

-----------------------------------

>Lycopodium_clavatum

---------------------------------------------MACNSLNVYGMDACL

GLEDVDYCDFSPSVRKTKCIKS-AIEPREVANMPLTALG---KILESTCSGGNKVSIIKS

SAQQDIDAFIENTIRSKS---------LQDAFYVLNLAVIVQLFYDWVAALPRVRPYYAV

KCNPSPPLLSTMAALGAGFDCASKSELEQVISMG-VSPQRIIFANPCKMPSHIKHASSVG

VNLTTYDCEHEVTKIKLNNPNAKLLLRLRADDLSS-------KWPLGVKYGA--LTSEVE

HLLMAAANAQVDVVGVSFHIGSGASD--ARSYLDAIAAARKVFEKAL-ALGLPAMHILDI

GGGFTVGN--NGELKLSEAANAINAALDQYFPEELG----VSIIAEPGRYFAEAPTTLAT

MVYGKRVRDEV---------------REYWINDGIYGTMNCLIHDYAVLCPRPLARISK-

----RNNTS-----C-AGLPVYKS---------------------TVFGPTCDSLDTVLK

EHPLP-DLVDGDWIVFPNMGAYTHCAGSSFNGYDTSAIQTFCVFSLNTRGPSTVAIDSLF

KSFETPCEFTDKLSFSEESTSEDSE----------

>Huperzia_serrata_1

--------------------------------------------MASCNSTVMYSLDAFL

GLENVDYCEFSCSGRKTKCAKSSAFEPREVGSMPLTTALNKVLESACNGLMISKVPIITS

SSQQDIDAFIESTIQSNN---------LQDAFYVLDLAVVVQLFNDWVAALPKVKPYYAV

KCNPSPSLLSTLAALGAGFDCASQSELELVTSMG-VSAQRIIFANPCKMPSHIKYATSVG

VNLTTYDCEHEVRKVKVHSPNAKLLLRLRADDRNS-------KWPLGVKYGA--LSSEVE

HLLMAVANAQVDVVGVSFHIGSGASD--ARSYLDAIAAARGVFEKAL-SMGLPAMHILDI

GGGFTVGN--NGELKLAEAAKVINAALEQYFPEELG----VSIIAEPGRYFAEAPTTLAA

MIYGKRVREEV---------------REYWINDGIYGTMNCLIHDYAVLCPRPLACASQ-

----RSNLS-----C-AKLPLHKS---------------------TVFGPTCDSLDTVLK

EHPLP-DLVDGDWIVFPNMGAYTHCAGPSFNGFDTSAIPTYCVFSLN-ARGSSVALDTLK

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46

TSFHTECDICDKLSSTS----TEESSPGEDSE---

>Huperzia_serrata_2

--------------------------------------------MASCNSTMMYSLDAFL

GLEDADYCEFSCSGRKTKCAKSSAFEPREVDSMPLTTALNKVLESACNG--LSKVPIITS

SSQQDIDAFIESTIQSNN---------LQDAFYVLDLAVVVQLFNDWVTALPKVKPYYAV

KCNPSPSLLSTLAALGAGFDCASQSELELVTSMG-VSAQRIIFANPCKMPSHIKYATSVG

VNLTTYDCEHEVRKVKVHSPNAKLLLRLRADDRNS-------KWPLGVKYGA--LSSEVE

HLLMAAANAQVDVVGVSFHIGSGASD--ARSYLDAIAAARGVFEKAL-SMGLPAMHILDI

GGGFTVGN--NGELKLAEAAKVINAALEQYFPEELG----VSIIAEPGRYFAEAPTTLAA

MIYGKRVREEV---------------REYWINDGIYGTMNCLIHDYAVLCPRPLACASQ-

----RSNVS-----C-AKLPLHKS---------------------TVFGPTCDSLDTVLK

EHPLP-DLVDGDWIVFPNMGAYTHCAGSSFNGFDTSAIPTYCVFSLN-ARGSSVALDTLK

TSFHTECDFCDKLSSTSTEASTEESSPGEDSE---

>Glycine_max_1

------------------------------------------------------------

-----MPSLVAEA--FQAN-GAEPLNLKPIFCASGIKGKR---VTAL--SAE--------

--KNGLTDFIQRIIADKP-------DI-DTPFSVLDLGVVMGLMDQWACKLPTVQPFYAV

KCNPNLSLIGALAALGSSFDCASKAEIESVLSLG-VSPDRIIYANPCKSESHIRYAASVG

VNVTTYDSIDEVEKIRKCHPTCELLLRIKPPQDSG------ARTSLGLKYGA--LPEEVD

ELLQAAHEAGLKVTGVSFHIGSGGAD--TRAYHGAISAAKNVFESAS-RLGLPRMGVLDI

GGGFTSG------PSFEAAALKINAAIEGSFGKEEG----LVVIGEPGRYFAETAFTLAT

RVIGKRVRGDV---------------REYWIDDGIYGTLNNIVFDYATVTCMPLACTSK-

----PENPTCCRD---LNLKTYPS---------------------TVFGPTCDSIDTVLR

DYQLP-ELQVNDWLVFPNMGAYTTSSGTNFNGFSSSAKSIFLACSSPEHT----------

--------MF-------------------------

>Glycine_max_2

------------------------------------------------------------

-----MPSLVAEA--FEAK-GAEPLSLKPIFSASGVKGKR---VTAL--SAE--------

--ANALTDFIQAIIADKP-------DI-DSPFSVLDLGVVMGLMDKWACKLPTVQPFYAV

KCNPNLSLIGALAALGSSFDCASKAEIESVLSLG-VSPDRIIYANPCKSESHIRYAASVG

VNVTTYDSLDEVEKIRNCHPTCELLLRIKPPQDSG------ARTSLGLKYGA--LPEEVH

ELLQAAHEAGLKVTGVSFHIGSGGAD--TRAYDGAISAAKNVFEMAS-GLGLPRMRVLDI

GGGFTSG------PPFEAAALKINAAIQASFGNEEG----LVVIGEPGRYFAETAFTLAT

RIIGKRVRGDV---------------REYWIDDGIYGTLNNIVFDYATVTCMPLACTSK-

----PENPRCSRE---LNLKTYPS---------------------TVFGPTCDSIDTVLR

DYKLP-GLQVNDWLVFPNMGAYTTSSGTNFNGFSSSAKSTFLAYSSPEHS----------

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47

--------MF-------------------------

>Medicago_truncatula

------------------------------------------------------------

-----MPTLVTEE--SQSQ----ITNLKPIFCASGVKGNK---VTTL--SSE--------

--VT-ISDFIQSIIKTKP------TEN-DSPFSVLDLRVIIDLMNKWTTELPTVKPFYAV

KCNPNISLIGTLASLGSNFDCASRAEIESVLSLG-VSPDKIIYANPCKSESHIKYAASVG

VNVTTFDCAGEVEKIKKWHPKCELLLRIKPEEDSG------ARSCLGLKYGA--LHNEVP

ELLKAADMAGLKVTGVSFHIGSGGAD--AKAYHGAILLAKEVFETAS-RLGMPKMKILDI

GGGFTSG------SKFDEAAFNVNDAIKTHFGNDED----LVVIGEPGRYFAETAFTLAT

KVIGKRVRGEM---------------REYWIDDGIYGTLNNIVFDYAIVKCMPLRFGSK-

----PENVICK------DPKTYPS---------------------TVFGPTCDSVDTVLK

EYELP-ELKVNDWLVFPNMGAYTTSSGTNFNGFSSSAEHIHIACSTPSLVGR--------

-----------------------------------

>Lotus_japonicus

------------------------------------------------------------

-----MPSLVSGE--IQAKDAAESLSLNPIFSASGVKGKR---VTAL--TKE--------

--CD-MSHLIESIIADKP-------DM-DSSFSVLDLGVVMELMDKWVTKFPTVQPFYAV

KCNPDISLIGALAALGSSFDCASKAEIQIVLSLG-ISPDRIVYANPCKSESDIKYAATVG

VNLATYDSVYEVDKVQKWHPKCELLLRIKYDSE-G------ALASLGVKYGA--LPEEVP

ELLKAAEAAGVNVTGVSFHIGSGGAD--PLALSGAIEAAKSVFEMAS-HFGMSRMSILDI

GGGFTCG------PELDVAATKVKAAILAHFGDHQG----LVVIAEPGRYFTETAFTLVS

RVIGKRVRGEL---------------REYWINDGVYGSISNIIYDHATIRCAPLRQ----

-----KNLTCV------DAKTYPT---------------------TVFGPTCDCIDIVLK

DYQLP-ELQVNDWLVFPNMGAYTISSGTNFNGFTSAVKHVYLACSEQS------------

-----------------------------------

>Populus_trichocarpa-1

------------------------------------------------------------

------------------------------------------------------------

---------MRSIISKEQ-ETKEP-------FYVLDLGVVSALLDKWTRTLPIVRPFYAV

KYNPVPALLGSLAALSSNFDCASQAEIELVLSLG-VSLDRIVYANPCKPGSHIKYAASVG

VNLTTFDSKEELDKIQKWHPKCALLIRIKALDDSR------ARCLLGSKYGA--LPEEVT

PFLEAAQTARLNVVGVSFHIGNRATY--SQAYEGAIASAKSVFEAAA-RFGMPRMTILNI

GGGFTAG------SLFDEAATSIKPALQAYFPNEPG----LTIISEPGRFFAESPFTLAT

NVIGKRVRGEL---------------REYWINDGIYGSLNCILNDHATITCTPLACNSN-

----SANPTCKG-----EKS-YSS---------------------MVFGPTCDALDTVLT

VHQLP-ELQVDDWLVFPNMGAYTAAAGSSFNGFNTAAILTYLSYSNLS------------

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48

-----------------------------------

>Populus_trichocarpa-2

------------------------------------------------------------

-----------------MGSIPKNPHAGVLLGAPGVKGKR---VTTISKN----------

----GLTEFMLSIISKKQ-ETKEP-------FYVLDLGEVTALMDKWLMTLPMVHPFYAV

KCNPDPALLGSLAALGSNFDCASRAEIESVLSLG-VSPNRIVYANPCKQESHIKYAASVG

VNLTTFDSKEELDKIRKWHSKCALLIRIKAPDDSG------ARCPLGPKYGA--LPEEVT

PLLQAAQTAQLNVVGVSFHIGSGATR--SRAYEGAIASAKSVFEAAV-RLGMPGMKILNI

GGGFTAG------SQFDEAATTIKSALQAYFPNEPG----LTVISEPGRFFAESAFTLAT

NIIGKRVRGDL---------------REYWINDGIYGSMNCILYDHATITCTPLACNSN-

----HANLTCKG-----LRA-YSS---------------------TVFGPTCDALDTVLT

GHQLP-ELQINDWLVFPHMGAYTAAAGSSFNGFNTAAILTHLASSNMN------------

-----------------------------------

>Manihot_esculenta-1

------------------------------------------------------------

-----------------MGSSPKNLHS--ILGAAGVKDKR---VSILPKD----------

----GLTNFTQSIIFKKQ-QTNEP-------FYVLDLGVVAALMDKWTRTLPMVRPFYAV

KCNPDPALTGTLAALGSNFDCASRVEIESILSLG-VAPERIIYANPCKAESHIKYAASVG

VNLTTFDSKEELEKIRKCHPQCALLIRVKAPDDGG------ARCPLGPKFGA--LPEEVT

PLLQAAKVARLKVVGVSFHIGSGATH--SRAYRGAIAAAKTVFEAAT-RLGMPKMNVLNI

GGGFTAG------SQFDEAAIVIKSALQAYFPNEPG----LTIISEPGRFFAESAFTLAT

NIIGKRVRGEL---------------REYWINDGIYGSMNCILYDHATITCTPLACTSN-

----RLNPACKG-----LRT-YSS---------------------TVFGPTCDALDTVLK

DHQLP-ELQVNDWLVFPCMGAYTAAAGSNFNGFNTGSILTYLAYSNPS------------

-----------------------------------

>Phaseolus_vulgaris-1

------------------------------------------------------------

-----MPTLVSEA--FQAR-SAEALSLKRVFSASGIKGKR---ITAL--SPK--------

--QNALTDFIQTLIAENP-------DI-DSPFGVLDLGVAMDLMDKWATKLPTVQPFYAV

KCNPNLSLIGALATLGASFDCASKAEIEAVLSLG-VSPDRIIYANPCKSASHIRYAATVG

VKVTTYDSKDEVEKIRKYHPTCELLLRIKPPQESG------ARCSLDLKFGA--LPEEVP

ELLSVAHAAGLKVTGVSFHIGSGGGD--AQAYHGAISAAKSVFDAAS-RLGMPRMRVLDI

GGGFTSG------PMFDAAAMKINAAIQDSFGNEEE----LVVIGEPGRYIAETAFTLAT

KVVGKRVRGEL---------------REYWIDDGIYGTLNNILFDHATVTCMPLAFTSK-

----PEDPSCR------DFKTYSS---------------------TVFGPTCDSLDTVLT

DYQLP-ELQTNDFLVFPNMGAYTTSCSTNFNGFSSSVNSIFLAYSQPYRAGTEHVLVESQ

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49

AEDGRFLNVFCS-----------------------

>Phaseolus_vulgaris-2

------------------------------------------------------------

-----MPTLVSEA--FQAR-SAEPLSLKRIFSASGIKGKR---ITVL--SPK--------

--QNALTDFIQTLIAENP-------DI-DSPFGVLDLGIVMGLMDKWATKLPTVQPFYAV

KCNPNLSLIGALAVLGASFDCASKAEIEAVLSLG-VSPDRIIYANPCKSASHIRYAATVG

VNVTTYDSKDEVEKIRKCHPTCELLLRIKPPQESG------ARR-LGVKFGA--LPEEVP

ELLSVAHAAGLKVTGVSFHIGSGGEN--AQAYQGAISAAKSVFDAAS-RLGMPRMRVLDI

GGGFTSG------PMFDAAAMKINAAIQDSFGNEEE----LVVIGEPGRYIAETAFTLAT

KVVGKRVRGEL---------------REYWIDDGIYGTFNHMYFDDATFTCMPLACTSK-

----PEDPSCR------DFKTYSS---------------------TVFGPTCDSLDTVLT

DYQLP-ELQANDFLVFPNMGAYTTSSSSNFNGFSSSVNSTFLAYSQPYRA----------

-------SMF-------------------------

>Theobroma_cacao-1

---------------------------------------------------------MPS

YLFRHLRSIWKYM--HSLIVSPFLS--LDQSRTMVSSSRS---LQAIISAGWLTRKRAAA

LSENELIAFIQSVISDEQQ---------TEPFYVLDLGVVVDLFDTWIRNLPMVQAFYAV

KCNPSPALLREMAALGSNFDCASRAEIEAILALG-VSPDRIVFANPCKAESHIKYAASVG

VNLTTFDSKDELEKIRKWHPECALLIRIKPPETSG------ARFQLGAKFGA--LPEEVV

PLLQAAQAAKFTVPGVSFHIGSGATH--FRAFEEAIAAAKTVFEKAA-HLGMPNMHLLNI

GGGFTAG------PRFTEAAPVVKTALQKYFFNEPG----LKVMAEPGLFFAQSSFTLVA

SIIGKRVRHEL---------------REYWINDGIYGSMNFLLYDHDDVILTPLACTSN-

----RGNPTCK-----GLK-TYDS---------------------TVFGPTCDAVDTVLK

GHPLP-ELQVNDWLVFHKMGAYTSACGTKFNGFDTCAISTYIAYSDQS------------

-----------------------------------

>Theobroma_cacao-2

------------------------------------------------------------

-----------------MGSSPRTLQA--IVGAPGVRGKK---VAALSKD----------

----GLTAFIQSIVSTKQ-EMKEP-------FYVLDLGVVMALFDKWARNLPMAQPFYAV

KCNPNPALLGALATLGSGFDCASKAEIESVLSLG-VSPGRIIFANPCKAESHIKYAATVG

VNLTTFDSKEELEKIKKWHPKCALLIRVKAPDDGG------ARCPLGPKYGA--LPEEVT

PLLQAAQTARLTVTGVSFHIGSGAMQ--FRAYREAIAAAKTVFETAA-RLGMPKMHVLNI

GGGFTAG------PQFAEAASTVKAALQAYFPNEPS----LTVIAEPGRFFAESAFTLAT

NIIGKRVRGDL---------------REYWINDGIYGSMNCILYDHAVVTCMPLARASS-

-------PRCKG-----ART-YDS---------------------TVFGPTCDALDTVLK

GYPLP-ELQVNDWLVFPNMGAYTAAAGSNFNGFNTSAILTYLAYSNPN------------

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50

-----------------------------------

>Gossypium_raimondii-1

-----------------------------------------------------------M

DIFLVISCIRNSF--FNKFSS-FLSNKVSKLRPMVGEAKL---IKNRVTK---------P

VSRDDLFHFIKSAISNEQQQ--------TDPFYVLDLGAIRSLVETWFDNLPVVQPFYAV

KCNPNPAFLKEMAALGTGFDCASLPEIETILSLG-VSPDRIVFANTCKPESHIKYAAKFG

VNLTTFDSNCELEKIKKWHPKCALLIRIKVPETSG------ATFKFGSKFGA--LPEEIV

PLLKAAQEAKLQVVGVSFHIGSRAIN--FHAFEDAIGAAKTTFDTAA-QLGLPKMHILDI

GGGFTSG------PKFTDAASAVKVALQKYFPDELADGN-LKIIAEPGRFFANSPFTLTT

SVIGKRERAEV---------------KEYWISDGISGSMNFLKYDHDEVICTPLIMK---

------NPTCK-----ELK-TWSS---------------------TVFGPTCDAADTVLK

GFELP-ELDVNDWLVFHNMGAYTSSRGNDFNGFKTSAIPT-IAYEN--------------

-----------------------------------

>Solanum_tuberosum

------------------------------------------------------------

--MAGQTVIVSGLNPAAILQSTIGGVPV---AAAAENGHT-RKVVPLSKD----------

----ALQDFMVSIITQKL-QDDKQ------PFYVLDLGEVVSLMEQWNSALPNIRPFYAV

KCNPEPSFLSMLSAMGSNFDCASRAEIEYVLSLG-ISPDRIVFANPCKPESDIIFAEKIG

VNLTTYDSEDEVYKIRKHHPKCELLLRIKPMNDGN------ARCPMGPKYGA--LPEEIE

PLLRTAQAARLTVSGVSFHIGSGDAD--SNAYLGAIAAAKQVFETAT-QLGMPKMTVLDI

GGGFTSG------HQFTSAAPAVKSALETHFQNSPE----LTIIAEPGRFFAETAFTLAT

TIIGKRVRGEL---------------KEYWINDGLYGSMNCVLYDHATVTATPLACMSN-

----RNNLNCGG-----SKT-FPS---------------------TVFGPTCDALDTVLR

DYQLP-ELQVNDWLVFPNMGAYTKAAGSNFNGFNTSAIGTHLAYAYPS------------

-----------------------------------

>Solanum_lycopersicum

------------------------------------------------------------

--MAGQTVIVSGLNPAAILQSTIGGAPV---AAAAENGHT-RKVVPLSKD----------

----ALQDFMVSIITQKL-QDDKQ------PFYVLDLGEVVSLMEQWNSALPNIRPFYAV

KCNPEPSFLSMLSAMGSNFDCASRAEIEYVLSHG-ISPDRIVFANPCKPESDIIFAEKIG

VNLTTYDSEDEVYKIRKHHPKCELLLRIKPMTDGN------ARCPMGPKYGA--LPEEIE

PLLRTAQAARLTVSGVSFHIGSGDAD--SNAYLGAIAAAKQVFETAA-QLGMPKMTVLDI

GGGFTSG------HQFTTAAPAVKSALETHFHDFPE----LTIIAEPGRFFAETAFTLAT

TIIGKRVRGEL---------------KEYWINDGLYGSMNCVLYDHATVTATPLACMSN-

----RNNLNCGG-----SKT-FPS---------------------TVFGPTCDALDTVLR

DYQLP-ELQVNDWLIFPNMGAYTKAAGSNFNGFNTSAIVTHLAYAYPN------------

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51

-----------------------------------

>Datura_stramonium

------------------------------------------------------------

--MAGQTVIVSGLNPAAILQSTIGGATP---APAAENDHT-RKVVPLSRD----------

----ALQDFMVSIITQKL-QDEKQ------PFYVLDLGEVVSLMDQWNAGLPNIRPFYAV

KCNPEPSFLSMLSAMGSNFDCASRAEIEYVLSLG-ISPDRIVFANPCKPESDIIFAAKVG

VNLTTFDSEDEVYKIRKHHPKCELLLRIKPMDDGN------ARCPMGPKYGA--LPEEVE

PLLRTAQAARLTVSGVSFHIGSGDAD--SKAYLGAIAAAKGVFETAA-RFGMSKMTVLDI

GGGFTSG------HQFTTASAAVRSALEQHFHDEQE----LTIIAEPGRFFAETAFTLAT

TIIGKRVRGEL---------------REYWINDGLYGSMNCVLYDHATVNATPLACMSN-

----RSNLNCGG-----SKT-FPS---------------------TVFGPTCDALDTVLR

DYQLP-ELQVNDWLIFPNMGAYTKAAGSNFNGFNTSAIVTHLAYAYPS------------

-----------------------------------

>Capsicum_annuum

------------------------------------------------------------

--MAGQTVIVSGLNPAAILQSTIGGAPPSTAAAAAENGDTTRKVVPLSKD----------

----ALQDFMVSIITQKL-QGEKK------PFYVLDLGEVVSLMDQWNVALPNVRPFYAV

KCNPEPSFLSMLAAMGSNFVCASRAEIEYVLSLG-ISPERIVFANPCKPESDIIFAEKVG

VNLTTYDSEDEVYKIKKHHPKCELLLRIKPMNDGN------ARCPMGPKYGA--LPEEIE

PLLRIAQASRLTVSGVSFHIGSGDAD--SNAYLGAIAAAKQVFETAA-KFGMSKMNVLDI

GGGFTSG------HQFTTAATAVKSALQQHFSNEPE----LTIIAEPGRFFAETAFTLAT

TIIGKRVRGDL---------------REYWINDGLYGSMNCVLYDHATVTATPLACMSN-

----RVNLNCSG-----SKM-FPS---------------------TIFGPTCDALDTVLR

DYHVP-ELQVNDWVIFPNMGAYTKAAGSNFNGFNTSAIVTHLAYAYPS------------

-----------------------------------

>Erythroxylum_coca

------------------------------------------------------------

-----------------MGSNARNLQA--VLGAPGVRGRR---VAALPKD----------

----GLTDFMQSIIMKRN-ESKEP-------FYVLDLGAVSGLMDKWSRTLPMVRPFYAV

KCNPEPALLGSLAAMGANFDCASRAEIEAVLSLR-VSPDRIVYANPCKQESHIKYAASVG

VNLTTFDSKDELEKMRKWHPKCALLLRVKAPEDGG------ARCPLGPKYGA--LPEEVI

PLLQAAQAARLSVVGASFHIGSGATH--FSSYRGAIAEAKKVFETAV-KMGMPRMTMLNI

GGGFTAG------SQFDEAATAIKSALQTYFPNEPG----LTIISEPGRFFAESAFTLAT

NVIGRRVRGEL---------------REYWINDGIYGSMNCILYDHATVTCKPLACTSS-

----RANPMCKG-----ARV-YNS---------------------TVFGPTCDALDTVMT

GHLLP-DLQVSDWLVFPNMGAYTAAAGSSFNGFKTAAILTYLAYSNP-------------

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52

-----------------------------------

>Nicotiana_benthamiana

------------------------------------------------------------

--MAGQTIIVSGLNPAAILQSTIGGGAFPTAAAAAENGTR--KVIPLSRD----------

----ALQDFMLSIITQKL-QDEKQ------PFYVLDLGEVVSLMDQWKSALPNIRPFYAV

KCNPEPSFLSILSAMGSNFDCASRAEIEYVLSLG-ISPDRIVFANPCKPESDIIFAAKVG

VNLTTYDSEDEVYKIRKHHPKSELLLRIKPMLDGN------ARCPMGPKYGA--LPEEVD

PLLRAAQTARLTVSGVSFHIGSGDAD--SNAYLGAIAAAKEVFETAA-KLGMSKMTVLDV

GGGFTSG------HQFTTAAVAVKSALKQHFDDEPG----LAIIAEPGRFFAETAFTLAT

TIIGKRVRGEL---------------REYWINDGLYGSMNCVLYDHATVNATPLAVLSN-

----RSNVTCGR-----SKT-FPT---------------------TVFGPTCDALDTVLR

DYQLP-ELQVNDWLVFPNMGAYTKAAGSNFNGFNTSAIVTHLAYSYPS------------

-----------------------------------

>Nicotiana_tabacum_1

------------------------------------------------------------

--MAGQTIIVSGLNPAAILQSTIGGGASPTAAAAAENGTR--KVIPLSRD----------

----ALQDFMLSIITQKL-QDEKQ------PFYVLDLGEVVSLMDQWKSALPNIRPFYAV

KCNPEPSFLSILSAMGSNFDCASRAEIEYVLSLG-ISPDRIVFANPCKPESDIIFAAKVG

VNLTTYDSEDEVYKIRKHHPKSELSVRIKPMLDGN------ARSAMGPKYGA--LPEEVD

PLLRAAQAARLTVSGVSFHIGSGDAD--SNAYLGAIAAAKEVFETAA-KLGMSKMTVLDV

GGGFTSG------HQFTTAAVAVKSALKQHFDDEPE----LTIIAEPGRFFAETAFTLAT

TIIGKRVRGEL---------------REYWINDGLYGSMNCVLYDHATVNATPLAVLSN-

----RSNVTCGG-----SKT-FPT---------------------TVFGPTCDALDTVLR

DYQLP-ELQVNDWLVFPNMGAYTKAAGSNFNGFNTSAIVTHLAYSYPS------------

-----------------------------------

>Nicotiana_tabacum_2

------------------------------------------------------------

--MAGQTIIVSGLNPAAILQSTIGGGASPTAAAAAENGTR--KVIPLSRD----------

----ALQDFMLSIITQKL-QDEKQ------PFYVLDLGEVVSLMDQWKSALPNIRPFYAV

KCNPEPSFLSILSAMGSNFDCASRAEIEYVLSLG-ISPDRIVFANPCKPESDIIFAAKVG

VNLTTYDSEDEVYKIRKHHPKSELLLRIKPMLDGN------ARCPMGPKYGA--LPEEVD

PLLRAAQAARLTVSGVSFHIGSGDAD--SNAYLGAIAAAKEVFETAA-KLGMSKMTVLDV

GGGFTSG------HQFTTAAVAVKSALKQHFDDEPE----LTIIAEPGRFFAETAFTLAT

TIIGKRVRGEL---------------REYWINDGLYGSMNCVLYDHATVNATPLAVLSN-

----RSNVTCGG-----SKT-FPT---------------------TVFGPTCDALDTVLR

DYQLP-ELQVNDWLVFPNMGAYTKAAGSNFNGFNTSAIVTHLAYSYPS------------

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53

-----------------------------------

>Nicotiana_tabacum_3

------------------------------------------------------------

--MAGQTIIVSGLNPAAILQSTIGGGASPT-AAAAENGTR--KVIPLSRD----------

----ALQDFMLSIITQKL-QDEKQ------PFYVLDLGEVVSLMDQWKSALPNIRPFYAV

KCNPEPSFLSILSAMGSNFDCASRAEIEYVLSLG-ISPDRIVFANPCKPESDIIFAAKVG

VNLTTYDSEDEVYKIRKHHPKSELLLRIKPMFDGN------ARCPMGPKYGA--LPEEVE

PLLRAAQAARLTVSGVSFHIGSGDAD--SNAYLGAIAAAKEVFETAA-KLGMSKMTVLDV

GGGFTSG------HQFTTAAVAVRSALKQHFDDQPE----LTIIAEPGRFFAETAFTLAT

TIIGKRVRGEL---------------REYWINDGLYGSMNCVLYDHATVNATPLAVLSN-

----RTNVTCGG-----SKT-FPT---------------------TVFGPTCDALDTVLR

DYQLP-ELQVNDWLVFPNMGAYTKAAGSNFNGFNTCAIVTHLAYTYPS------------

-----------------------------------

>Nicotiana_glutinosa

------------------------------------------------------------

--MAGQTIIVSGLNPAAILQSTIGGGASPT-AAAAENGTR--KVIPLSRD----------

----ALQDFMLSIITQKL-QDEKQ------PFYVLDLGEVVSLMDQWKSSLPNIRPFYAV

KCNPEPSFLSILSAMGSNFDCASRAEIEYVLALG-ISPDRIVFANPCKPESDIIFAAKVG

VNLTTYDSEDEVYKIRKHHPKSELLPRIKPMFDGN------ARCPMGPKYGA--LPEEVE

PLLRAAQAARLTVSGVSFHIGSGDAD--SNAYLGAIAAAKEVFETAA-KLGMSKMTVLDV

GGGFTSG------HQFTTAAVAVKSALKQHFDDEPE----LTIIAEPGRFFAETAFTLAT

TVIGKRVRGEL---------------REYWINDGLYGSMNCVLYDHATVNATPLAVLSN-

----RTNVTCGG-----SKT-FPT---------------------TVFGPTCDALDTVLR

DYQLP-ELQVNDWLVFPNMGAYTKAAGSNFNGFNTSTIVTHLAYTYPS------------

-----------------------------------

>Nicotiana_glauca

------------------------------------------------------------

--MAGQTIIVSGLNPAAILQSTIGGGASPTAAAAAENGTR--KVIPLSRD----------

----ALQDFMLSIITQKL-QDEKQ------PFYVLDLGEVVSLMDQWKSALPNIRPFYAV

KCNPEPSFLSILSAMGSNFDCASRAEIEYVLALG-ISPDRIVFANPCKPESDIIFAAKVG

VNLTTYDSEDEVYKIRKHHPKSELLLRIKPMFDGN------ARCPMGPKYGA--LPEEVE

PLLRAAQAARLTVSGVSFHIGSGDAD--SNAYLGAIAAAKEVFETAA-KLGMSKMTVLDV

GGGFTSG------HQFTAAAVAVKSALKQRFDDEPE----LTIIAEPGRFFAETAFTLAT

TIIGKRVRGEL---------------REYWINDGLYGSMNCVLYDHATVNATPLAVQSN-

----RSNVTCGG-----SKT-FPT---------------------TVFGPTCDALDTVLR

DYQLP-ELQVNDWLVFPNMGAYTKAAGSNFNGFNTSAIVTHLAYAYPS------------

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54

-----------------------------------

>Citrus_clementina

------------------------------------------------------------

-----MASCPKGT--PSTLLH---------LDAQVMGGQR---VTTVVTK----------

---EELTEFVRSTILKRQEFD-------EVPFYILDLGVVVTLYNQMISKLPMIHPHYAV

KCNPEPALLEALAALGSNFDCASRSEIEAVLALG-VSPDRIIYANPCKPVSHIKYAANVG

VNLTTFDSVEELHKIRKWHPKCDLLIRIKPPDDSG------AKHPLDSKYGVDHHPQEIV

PLLEAAEASGLSVVGVAFHIGSAATK--FAAYRGAIAAAKAVFETAA-RLGNNKMRVLDI

GGGFSFTN--SNTKSFQEAASIIKEALHAYFPNELLPGSSLRVISEPGRFFTYSAFTLYT

QIIGKRVHGEM---------------RNYWINDGKYGSFDWVNYDEAIAKCTPLTLASS-

------LTTSK-----GLSRTYNS---------------------KVFGPTCDAADEVFS

GHKLP-ELEVTDWLVFSEMGAYTRARGTNFNGYNTAAIPTYVVRSNRT------------

-----------------------------------

>Citrus_sinensis-1

------------------------------------------------------------

-----------------------------------MGGQR---VTTVVTK----------

---EELTEFVRSTILKRQEFD-------EVPFYILDLGVVVTLYNQMISKLPMIHPHYAV

KCNPEPALLEALAALGSNFDCASRSEIEAVLALG-VSPDRIIYANPCKPVSHIKYAANVG

VNLTTFDSVEELHKIRKWHPKCDLLIRIKPPDDSG------AKHPLDSKYGVDHHPQEIV

PLLEAAEASGLSVVGVAFHIGSAATK--FAAYRGAIAAAKAVFETAA-RLGNNKMRVLDI

GGGFSFTN--SNTKSFQEAASIIKEALHAYFPNELLPGSSLRVISEPGRFFTYSAFTLYT

QIIGKRVHGEM---------------RNYWINDGKYGSFDWVNYDEAIAKCTPLTLASS-

------LTTSK-----GLSRTYNS---------------------KVFGPTCDAADEVFS

GHKLP-ELEVTDWLVFSEMGAYTRARGTNFNGYNTAAIPTYVVRSNRT------------

-----------------------------------

>Citrus_sinensis-2

------------------------------------------------------------

-----MASCPKGT--PSTLLH---------LDAQVMGGQR---VTTVVTK----------

---DELTEFMQSTILKRQEFD-------EVPFYLMDLGVVVSLYNHMISNLPMIHPHYAV

KCNPEPALLEALAALGSNFDCGSRSEIEAVLLLD-VSPDRIIYANPCKPVSHIKYAASVG

VNLTTVDSVEELDKIRNWHPKSDLLIRIKSPDDSG------AKYPLDSKYGAGHHPQEIM

PLLKAAEASGLSVVGVSFHVGSEATN--FAAFRGAIAAAKAVFDTAA-RTSNNKMR----

-------------------------KLFKLIFRELLPGSSLKVISEPGRFFAASAFTLYA

QIIGKRVRGEL---------------REYWINDGKFGSLAWVTCDEAIAKCTPLPFASS-

------FTTSK-----GLTRTYNS---------------------TVFGPTCDAFDEVFT

GHKLP-ELEVNDWLVFSEMGAYTTACGTNFNGYSTVAIPTYVVRSNQTLLAI--------

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55

-----------------------------------

>Hordeum_vulgare_subsp._vulgare

------------------------------------------------------------

-----------------MVGSSP---MQAVLVAPGVKDKK---VLAFRR-DALK------

-EKDAVSALMRTIAAG----------GVRSAFYVFDLARVVDLYRGWRRALPGVRSCYAV

KCNPEPALLGALAALGAGFDCASRREMEAVLALG-VQPGSIVYANPCKPEAHLEYAAEVG

VNLATYDSEEEVVKVKRCHPGCELILRIKGPDGGEAR------VDLGTKYGAH--EDEVL

PLLRAAQREGLNVAGVSFHVGSGASN--TDVYRGAIEAARGVFDTAA-ALGMPPMRVLDI

GGGFMAG------PAFDEAAAVINAALERYFGE-LPC---VEVIGEPGRYFAETAFTMAA

RVIGKRTRGEV---------------REYWIDDGLYGTLSCIPMDHYVPRPRPLAA-PRA

----GEK-------------TYTS---------------------TVFGPTCDSLDTVVT

GYQLP-EMSVGDWLVFDDMGAYTTASGSNFNGFSTSDIKTYLAYSS--------------

-----------------------------------

>Zea_mays-1

------------------------------------------------------------

-----------------MDGGSP---MQTVLSAPGVKDKK---LVSFTRNDDAT------

NDKDAVTGLIRSIVGGAT----PSSPAQRTAFHVFHINTVVDLFSAWRRGLPDVRPYYAV

KCNPEPALLGALAALGAGFDCASRAEMEAVLALG-VPPGRIVYANPCKPEPHLEYAAGAG

VSLATYDTEDEVAKVARCHPGCQLLLRLKAPDGGVS------GGDLMNKYGAH--AHEVA

PLLRAAQRAGVGVAGVSFHVGSPVSR--VDVYRGAIQAARAAFDQAV-ALGMPPMRVLDV

GGGFTAG------AAFDEAAAVIRDALDRSFRDLRPC---VEVVAEPGRYFATTAFTLAA

RVIGRRARGAA---------------REYWIDDGVYGSLNNVLMDHKAPRPRPLASCPRP

----GEE-------------TYAS---------------------TVFGPTCDSQDKVVT

GYQLP-EMSVGDWLVFDDMGAYSTSAGSRFNGFDSSEIKIYVAYSS--------------

-----------------------------------

>Zea_mays-2

MASRGHSYIWRQTHAEQPRTHTKRRVSPDDLLASGPAWHHLPGPLDRSSSRQHEFSIEQV

RSRCSSIARVVNRLVITMVGSSP---LQAVLVAPGVKDRK---VLAFKR-DALK------

-DKDAVSGLIHSILAS--------SPAQRSAFYVFDLAKVVDLFRAWRRALPDARPCYAV

KCNPDPALLGALAALGAGFDCASRAEIEAVLALG-VRPGDIVYANPCKPEAHLEYAAEVG

VNLTTYDSEEEVAKVRRCHPGCELLLRLKGPDGGDVR------VDLGTKYGAH--PDEVV

PLLRAAQRAGVGVAGVSFHVGSGASN--LHVYRGAIQAARAAFDAAA-ALGMPPMRVLDI

GGGFVSG------PTFDDAAAVINDALAHHFGD-LPC---VEVIAEPGRYFAETAFTLAA

RVIGKRTRGEV---------------REYWIDDGLYGSLNCIIMDHYVPTPRPLAS-PRP

----GDK-------------TYTS---------------------TVFGPTCDSLDTVLT

GYLLP-EMSVGDWLVFDDMGAYTTGAGSNFNGYATSDIKIYVAYSS--------------

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56

-----------------------------------

>Zea_mays-3

------------------------------------------------------------

-----------------MGGGSR---MQTVLLAPGVKDKK---LLSYTRRN-AL------

KEKDAVTDLIRSIIA-------TSSPVQRTAFHVFRIDNVLELYSAWRRGLPDVRPYYAV

KCNPEPALLGALAELGAGFDCASRAEIEAVLALG-VPPSSIIYANPCKSEPHLEYAAAAG

VNLTTYDTEEEVAKVKRCHPRCELLLRLKGPDGSET------TCDLGTKYGAR--ADEVV

PLLRAVQRAGVTVAGVSFHVGSPVAR--VGVYRAAIEAARAAFDEAA-ALGMPPMRVLDI

GGGFTAG------ASFDDAAAVINDALARSFGD-LPC---VEVIGEPGRYFCETAFTLAA

RVIGKRTRGEV---------------REYWIDDGLYGSLNNILMDHKVPRPRPLAT-PRP

----GDR-------------THTS---------------------TVFGPTCDSQDEVVT

GYQLP-EMSVGDWLVFDNMGAYSTGSGSKFNGFDTSEIKIYVAYSS--------------

-----------------------------------

>Sorghum_bicolor-1

------------------------------------------------------------

-----------------MVGSSP---VQAVLAAPGVRDRK---VLAFKS-DAHKG-----

NKQDVASGLVHSILAST-------SPPQRSAFYVLDLAKVVDLFRAWRRALPDARPCYAV

KCNPDPALLGALAALGAGFDCASRAEIEAVLALG-VQPRDIVYANPCKPEAHLEYAAEVG

VNLTTYDSEEEVAKVRRCHPACELLLRLKGPDGGGVR------VDLGTKYGAH--ADEVV

PLLRAAQRAGVGVAGVSFHVGSGASI--LAVYSGAIQAARAAFDAAA-ALGMPPMRVLDI

GGGFVSG------PTFDDAAAVINDALAQHFGD-LPC---VEVIGEPGRYFAETAFTLAA

RVIGKRTRGEV---------------REYWIDDGLYGSLNCVIMDHYVPTPRPLAS-PRP

----GDK-------------TYTS---------------------TVFGPTCDSFDTVVT

GYQLP-EMSVGDWLVFDDMGAYTTGAGSNFNGYATSDIKIYVAYSS--------------

-----------------------------------

>Sorghum_bicolor-2

------------------------------------------------------------

-----------------MGEGTDDAMPQTVLSAPGVKDRK---VVSFTTTNDDK------

DD--AVAGLIRSIIA-------TSSPAQRTAFHVFHINTVVDLFSAWRRALPDVRPFYAV

KCNPDPALLGALAALGAGFDCASRAEMEAVLALG-VGVGDLIYANPCKAEPHLEYAAAAG

VALATYDTESEVAKVARCHPNCELLLRLKGPDGGTTVAGGGRGGDLMNKYGAH--ADEVS

PLLRAAQRAGVRVAGVSFHVGSPVSRSRVGVYRGAIESARAAFDAAA-ALGMPPMRVLDI

GGGFSAG------AAFDEAAAVINGALADAFGDLLRCRR-VEVIAEPGRYFAETAFTLAA

RVIGRRARGEA---------------REYWIDDGLYGSLNNVLMDHKVPRPRPLAAGGEE

----KTT-------------THSS---------------------TVFGPTCDSQDQVVT

GYPLP-EMSVGDWLVFDDMGAYSTGAGSKFNGFDISEMKIYVAYSS--------------

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57

-----------------------------------

>Setaria_italica-1

------------------------------------------------------------

-----------------MVGSSP---MQAVLVAPGVKDRK---VLAFERSGALK------

-DKDAATGLVRAILAA--------NPAQRSAFYVFDLAKVIDLFRAWRRALAGVRPCYAV

KCNPDPALLGALAALGAGFDCASRAEIEAVLALG-VHPRDIVYANPCKPEPHLEYAAEVG

VSLATYDSEEEVAKVKRCHPGCELLLRLKGPDGGDVR------VDLGTKYGAH--ADEVV

PLLRAAQRAGVSVAGVSFHVGSGATN--LGVYRGAIQAARAAFDAAA-ALGMPPMRVLDI

GGGFVSG------PTFDDAAAVINDALAQHFGD-LPR---VEVIGEPGRYFAETALTLAA

RVIGKRTRGEV---------------REYWIDDGLYGSLNCIIMDHYVPTPRPLAS-PRP

----GEK-------------TYTS---------------------TVFGPTCDSLDTVVT

GYQLP-EMSVGDWLVFDDMGAYTTGAGSNFNGFATSDIKIYVAYSS--------------

-----------------------------------

>Panicum_virgatum-1

------------------------------------------------------------

-----------------MVGSSP---LQAVLVAPGVKDRK---VLAFERRDALK------

-DKDAASGLLRAVLAS--------NPAQRTAFYAFDLARVADLYWAWRRALAGVRPCYAV

KCNPDPALLGALAALGAGFDCASRAEIEAVLALG-VRPRDIVYANPCKPEPHLEYAAQVG

VNLATYDSEEEVAKVKRCHPDCELLLRLKGPDGGDAR------VDLGTKYGAH--ADEIV

PLLRAAQRAGVTAAGVSFHVGSGASN--LAVYRGAIEAARAAFDAAA-ALGMPPMRVLDI

GGGFVSG------PTFDEAAAVINDALAQHFGD-LPC---VEVIGEPGRYFAETAFTLAA

RVIGKRTRGEV---------------REYWIDDGLYGSLNCVIMDHYVPTPRPLAA-PRP

----GEK-------------TYTS---------------------TVFGPTCDSLDTVVT

GYQLP-EMSVGDWLVFDNMGAYTTGAGSNFNGFATSDIKIYVAYSTS-------------

-----------------------------------

>Panicum_virgatum-2

------------------------------------------------------------

-----------------MVGSSP---LQAMLVAPGVKDRK---VLAFERRDALK------

-DKDAASGLLRAVLAS--------NPAQRTAFYAFDLARAADLYWAWRRALAGVRPCYAV

KCNPDPALLGALAALGAGFDCASRAEIEAVLALG-VRPRDIVYANPCKPEPHLEYAAEVG

VSLATYDSEEEVAKVKRCHPNCELLLRLKGPDGGDAR------VDLGTKYGAH--ADEVV

PLLRAAQCAGVTVAGVSFHVGSGANN--LAVYRGAIEAARAAFDAAA-ALGMPPMRVLDV

GGGFVSG------PTFDEAAAVINDALAQHFGD-LPC---VEVIGEPGRYFAETAFTLAA

RVIGKRTRGEV---------------REYWIDDGLYGSLNCIVMDHYVPTPRPLAT-PRP

----GEK-------------TYTS---------------------TVFGPTCDSLDTVVT

GYQLP-EMSVGDWLVFDNMGAYTTGAGSNFNGFATSDIKIYVAYSS--------------

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58

-----------------------------------

>Oryza_sativa-1

------------------------------------------------------------

--------------------------MQAVLMAPGVKDKK---VLAFKRGKGKD------

-ADAGVTALIRDIVAG----------GARSAFHVFDLAKVVDLHRGWRRALPDVRPCYAV

KCNPDGAMLAALAALGAGFDCASRAEIEAVLALG-VRPATIVYANPCKPEAHLEYAAEVG

VNLTTYDSEEEVAKVRRCHPRCELLLRIKAPDSGDAK------VDLGLKYGAN--PDEVL

PLLRAAQREGVAVAGVSFHVGSGASR--ADVYRGAIEAAREAFDAAA-ALGMPPMRVLDI

GGGFMAG------RTFDEAAAVINRALERHFGD-LPC---VEVIGEPGRYFAETAFTLAA

RVIGKRTRGEL---------------REYWIDDGLYGSLNCILMDHYVPRPRPLAA-AAA

----GEDTTAAT--------THAS---------------------TVFGPTCDSLDTVVT

GYQLP-EMSVGDWLVFDDMGAYTTAAGSNFNGFATSAIKIHLAYSS--------------

-----------------------------------

>Brachypodium_distachyon

------------------------------------------------------------

--------------------------MQAMLTAPGVKDRK---VLAFKR-DALK------

-DKDAVSGLLRSIAAR---------DAVRSAFYVFDLARVVDLHRGWRRALAGVRPCYAV

KCNPEPALLGALAALGAGFDCASRREIEAVLALG-VEPGSIVYANPCKPEAHLEYAASVG

VNLATYDSEEEVAKVKRCHPGCELILRIKGPDGGDVR------VDLGTKYGAH--PEEVV

PLLRAAQRAGLNVAGVSFHVGSGASN--TDVYRGAIEAARGVFDAAA-ALGMPPMRVLDI

GGGFMAG------PAFEEAAAVINGALEKYFGE-LPC---VEVIGEPGRYFAETAFTMAA

RVIGKRTRGEV---------------REYWIDDGLYGTLSCIPMDHYVPRPRPLAA-SRP

----GEK-------------TFTS---------------------TVFGPTCDSLDTVVT

GYQLP-EMSVGDWLVFDDMGAYTTASGSNFNGFSTSDINIYLAYSS--------------

-----------------------------------

>Selaginella_moellendorffii

------------------------------------------------------------

------------------------------------------------------------

-----MDSFIRKKIQSTG---------REDAFYVLDLATVTRLWKIWKSAMPRVHPFYAV

KCNPDPQLLSMLAALGAGFDVASKAELEAVTQLG-VAPRNIIFANPCKLPSHITEAAKAG

VVYTTFDSEGELYKLKKYHPQAEVLLRFRADDTGA-------RCPLGVKYGAE--WDECY

HLLEVAKTLGIKVAGVAFHVGSGASD--VNAFAEGIKAARKLFDMAE-SLGLPRMTMLDI

GGGFVSDG--GAGVKFAAAAYEIGNALEEHFPRETMAD--VRIIGEPGRFFAEEAFSLAV

LVFGCRVRRREEGNKT---------VVEYWINDGIYGSMNCLLYDHATLSVRALPVASSG

-----GGSSGSS-------SGSDCESSSEDEEDDAPLLDVELHPSIIFGPTCDGLDTVLS

DVWLP-RLQCGDWLVFPRMGAYTKSAGSSFNGFAVPDATFYVHCGAAPEM----------

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59

-----------------------------------

>Coccomyxa_subellipsoidea_C-169-1

------------------------------------------------------------

------------------------------------------------------------

--------------------------------------------------MPRVTPFYAV

KCMPDRAMMSTLAALGTGFDCASPAEIDAVLSLG-VPPERIIYAHPVKSPAQIRHAAARR

VAMTTADSSGEMEKLAHWHPTAKVLLRIRADDASA-------LCCLGTKYGAE--VADAP

GILAAAAALGVDIVGVSFHVGSASRD--PKAFEVAIRLARGVFDVGA-SLGLHNMRILDI

GGGLTAQ--VTG---IWDVPGVVNAALDAHFPPGCG----YDIIAEPGRYFAEAVGTLLC

AVNGKR---ERQTPTG--------RSADYWLSDGLYGSFNGILYDHMVPTPVALPINNIP

HH----NEIPKG--------ATTA---------------------SLFGPTCDGADVICR

DVSLP-NLDVGDFVAFPKLGAYSWAGACNFNGFEAIGVHFFYVTT---------------

-----------------------------------

>Coccomyxa_subellipsoidea_C-169-2

------------------------------------------------------------

------------------------------------------------------------

--------------------------------------------------MPRVTPFYAV

KCNNDEAILSALAALGAGFDCASDAELDMVLELG-VPTGRIVFANACKRPRDIRRAAEKQ

ANLTTFDTASELAKLARWHPATRALLRIRADDPAA-------RCQLGNKYGAD--PSEVP

ALLQAAKEMGIEVCGISFHVGSGATN--PDAFSEAIALARTAFDAGT-GLGF-TMDLLDI

GGGFCEG------RVMGDVAVAVNTALALHFPVSSG----VRIIAEPGRYFAESCATFGS

MVFGVRDGRCAKSGAA---------IRDYWITDGIYGSMNSLLYDHATVAPRPLHMMTNE

AVNGATDLTDG--------PMLRG---------------------CVFGPTCDGLDTVLH

DYALP-NLDVGDWLVFRNHGAYTFVGACPFNGMDPAPATFYVFSEN--------------

-----------------------------------

>Saccharomyces_cerevisiae

------------------------------------------------------------

---MSSTQVGNALSSSTTTLVDLSNSTVTQKKQYYKDGETLHNLLLELKNNQDLELLPHE

QAHPKIFQALKARIGRINNETCDP--GEENSFFICDLGEVKRLFNNWVKELPRIKPFYAV

KCNPDTKVLSLLAELGVNFDCASKVEIDRVLSMN-ISPDRIVYANPCKVASFIRYAASKN

VMKSTFDNVEELHKIKKFHPESQLLLRIATDDSTA-------QCRLSTKYGCE--MENVD

VLLKAIKELGLNLAGVSFHVGSGASD--FTSLYKAVRDARTVFDKAANEYGLPPLKILDV

GGGFQFES-------FKESTAVLRLALEEFFPVGCG----VDIIAEPGRYFVATAFTLAS

HVIAKRKLSEN--------------EAMIYTNDGVYGNMNCILFDHQEPHPRTLYHNLEF

HYDDFESTTAVLDSINKTRSEYPYK-------------------VSIWGPTCDGLDCIAK

EYYMKHDVIVGDWFYFPALGAYTSSAATQFNGFEQTADIVYIDSELD-------------

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60

-----------------------------------

>Trypanosoma_brucei

------------------------------------------------------------

--------MTTKSTPSSLSVNCLVAQTEKSMDIVVNDDLSCRFLEG-FNTRD--------

----ALCKKIS-MNTCDE----------GDPFFVADLGDIVRKHETWKKCLPRVTPFYAV

KCNDDWRVLGTLAALGTGFDCASNTEIQRVRGIG-VPPEKIIYANPCKQISHIRYARDSG

VDVMTFDCVDELEKVAKTHPKAKMVLRISTDDSLA-------RCRLSVKFGAK--VEDCR

FILEQAKKLNIDVTGVSFHVGSGSTD--ASTFAQAISDSRFVFDMGT-ELGFN-MHILDI

GGGFPGT--RDAPLKFEEIAGVINNALEKHFPPDLK----LTIVAEPGRYYVASAFTLAV

NVIAKKVTPGVQTDVGAHAESN-AQSFMYYVNDGVYGSFNCILYDHAVVRPLPQ---REP

IP----NEK-----------LYPS---------------------SVWGPTCDGLDQIVE

RYYLP-EMQVGEWLLFEDMGAYTVVGTSSFNGFQSPTIYYVVSGLPDHVVRELK------

--------------SQKS-----------------

>Xenopus_laevis

------------------------------------------------------------

------------------------------MNSFSNDDFDFSFLEEGFSARD--------

----IVEQKINEVSLSDD----------KDAFYVADFGDIVKKHVRWFKALPRVTPFYAV

KCNDGKAIVKTLSILGAGFDCASKTEIQLVQSIG-VSPERIIYANPCKQVSQIKYAASCG

VEKMTFDSEVELMKVARNHPNAKLVLRIATDDSKA-------VCRLSVKFGAT--LKTSR

LLLERAKELNVDIIGVSFHVGSGCTD--PQTYVQAVSDARCVFDMGA-ELGFN-MHLLDI

GGGFPGS--EDVKLKFEEITSVINPALDKYFPADSG----VKIIAEPGRYYVASSFTLAV

NIIAKKVMVNEQSGSDDEEDAANDKTLMYYVNDGVYGSFNCILFDHAHVKPVLT---KKP

KP----DEK-----------FYSS---------------------SIWGPTCDGLDRIVE

RFELP-ELQVGDWMLFENMGAYTVAAASTFNGFQRPTLYYVMSRPHWQLMHDIKEHGILP

EVP--DLSALHVSCAQESGMELAPAVCTAASINV-

>Homo_sapiens

------------------------------------------------------------

------------------------------MNNFGNEEFDCHFLDEGFTAKD--------

----ILDQKINEVSSSDD----------KDAFYVADLGDILKKHLRWLKALPRVTPFYAV

KCNDSKAIVKTLAATGTGFDCASKTEIQLVQSLG-VPPERIIYANPCKQVSQIKYAANNG

VQMMTFDSEVELMKVARAHPKAKLVLRIATDDSKA-------VCRLSVKFGAT--LRTSR

LLLERAKELNIDVVGVSFHVGSGCTD--PETFVQAISDARCVFDMGA-EVGFS-MYLLDI

GGGFPGS--EDVKLKFEEITGVINPALDKYFPSDSG----VRIIAEPGRYYVASAFTLAV

NIIAKKIVLKEQTGSDDEDESS-EQTFMYYVNDGVYGSFNCILYDHAHVKPLLQ---KRP

KP----DEK-----------YYSS---------------------SIWGPTCDGLDRIVE

RCDLP-EMHVGDWMLFENMGAYTVAAASTFNGFQRPTIYYVMSGPAWQLMQQFQNPDFPP

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61

EVEEQDASTLPVSCAWESGMKRHRAACASASINVL

>Nelumbo_nucifera

------------------------------------------------------------

-----------------------------ILSSPGIRGRR---VTSLGASSEATN-----

---QPLLDLIQSIAKRQEQKD---------PFYVLDMGVVLSVWEKWNESLPMVKPYYAV

KCNPDPALVSGLAALGANFDCASRAEIEAVLALG-VSADRIIYANPCKSETHIRYAAGVG

VNLTTFDSKEEVEKLRKLHPRCRLLLRFKAPDDAE------ARCPLGPKYGA--LPEEVV

PLLQAAHAAHLPIVGVSFHVGSGATQ--FGAYSGAIAFARSVFDTAE-GLGLPRMRVLNI

GGGFTFG------PQFADASATIRAALKTHFPAESG----VTVISEPGRFFAETPFTLAT

TIIGKRVRGEI---------------REYWINDGIYGSMNCLLFDYATITAQPLACWSN-

----RLNPACAG------MRQYTS---------------------TVFGPTCDARDTVLS

EVLLP-DLYVSDWLVFPNMGAYTTAAGSSFNGFSTAAIPTHVAYS---------------

-----------------------------------

>Nuphar_advena

------------------------------------------------------------

-------------------------SLQAILSSPAVKGRR---VTSLIQSHDRR------

---ESMLELIQSIAKKQELSD---------PFYVLDMGVVLNLWEKWHECLPMVPPYYAV

KCNPEPAFLSALAALGANFDCASRAEIEAVFALG-VSADRIIYANPCKSESQIRYAASVG

VNLTTYDSKEEVEKLRKLHPKCSLLLRIKVHDDGT------ARWPLGSKYGA--LSEEVL

PLLQAAHATGLPVVGVSFHVGSGATE--SQAYASAIALARSVFDSAT-RLGMPRMRMLNI

GGGFTSG------LQFEDASSVIRAALKLHFPSDSG----VSFMAEPGQYFAGTAFTLVA

NIIGKRVRGEL---------------REYWINEGIYGSMNFLLHDYATLTVEPLACWSN-

----QANPRCIG------MRQHLS---------------------TVFGQTLDSLDTVQT

GIRLP-ELHVNDWLVFPNMGAYTAAVGSRFNGFDTSAIITYLAYS---------------

-----------------------------------

>Nothotsuga_longibracteata

------------------------------------------------------------

-----------------------------VLATPGVKNRK---VLPLRSRSQ--------

---KAVNEMAQSIIDNDD---------VKDPFYILDLGVVVELWQKWQEALPRVQLFYSV

KCNPEPALLSALATLAAGFECTSAAEIEDILKLG-VSPHRIVYSNPCKAETQLKYAANVG

VNLTTFDSIEEVEKIKKFHPRCALLLTMKVPDEDVRS----ARFPLGSKYGA--LPEEVG

PLLQAAQRGGIAVAGVSFHVGNGVSH--YRVYTSAVAAVRGVFDTAS-RLGLPKLGILNI

GGGFSAG------PQFDEAAGTVRSALETYFPDETA----VSVMGEPGRYFAESAFWLVT

NVIGKRARGEV---------------REYWINDGIYGSMSCLLHDNAVLTALPLACKSR-

----RSNTSCTG------LPKYRS---------------------TVFGQTCTSVDTVLT

DYMLP-ELAVGDWLVFPNMGAYTAATASNFNGFSISAIRTYCA-----------------

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62

-----------------------------------

>Microstrobos_fitzgeraldii

------------------------------------------------------------

-----------------------------VLAAPGVKSRK---VATLRCRSQ--------

---EAINELVQSIIEKEG---------TNEPFYILDIGMVVELLQKWQQSLPLVRPFYAV

KCNPEPALLWALATLGVGFDCASRAEIEAVLAVG-VSSDRIIYANPCKAETQLRYAAKVG

VNLTTFDSTEEVDKIKNSHPRCSLVLRIRAPEDGN------ARCPLGPKYGA--LPEEVA

PLLQAAHRAGLSVAGVSFHVGSGASN--AGVYTGAIAAAKSVFQTAA-RLGLPKLRILNI

GGGFTAG------PRFADAAATVKAALDSYFPD-SSS---VSLIGEPGRYFAESAFTLAT

NVIGKRVRGDL---------------REYWINDGIYGSMNCLLYDHAVITALPLACASR-

----RSNPSCKG------LPKHRS---------------------TVFGPTCDALDTVMT

DHWLP-ELQVGDWLVFPNMGAYTAAAGSNFNGFSTSAIRTYCAAS---------------

-----------------------------------

>Tetraclinis_sp.

------------------------------------------------------------

----------------------------VVMGASRLRGQK---VSTLRSRTQ--------

---DSVNELMQAIIDREG---------SNEAFYVVDLGVVVDLWQKWQEALPGVRPFYAV

KCNPEPLLLNSLAILGAGFDCASRAEIEAVLSLG-VSADRIVYANPCKAESQLKYAAKVG

VNLTTFDSKEEIEKIRSSHPRCEVILRVKGQEDGG------ARCPLGSKYGA--LAEEIG

PLLQAAQRAGLTVAGVSFHVGSGAEH--ARAYTAAINAVKNAFDTAS-KLGLPRLKIVNI

GGGFTAG------PRFTEASAAVRAALSGNFPGNPSG---ISVIAEPGRYFAESAFSLAT

NIIGKRVRGDL---------------REYWINDGIYGSMNCLLYDHAVITALPLACLSR-

----RANPSCNG------LPKYRS---------------------TVFGPTCDALDTVLT

DHWLP-ELQVGDWLVFPNMGAYTAAAGSNFNGFSTSAICTYCAVS---------------

-----------------------------------

>Pinus_radiata

------------------------------------------------------------

-----------------------------VLAAPGMKNRK---VTALKSRSQ--------

---EAVNEMALTIIENGD---------VNSPFYIHDLGVVVDLWQKWQAALPRVQPFYAV

KCNPDPTLLSALATLGSGFDCASRAEIEAILKLG-VSADRIVYANPCKAETQLQYAADVG

VNLTTFDSVDEVEKIRKFHPRCALLLRVKVPEEDAGG----ARCPLGPKYGA--LPEEVG

PLLEAAQSSGLAVSGVSFHVGSGVAR--SRVYATAVGAVRGVFDTAS-RLGLPTLRIINI

GGGFTAG------PTFAEAAGTVRAALKTHFPDETE----VSVIAEPGRYFAESAFTLAT

NVIGKRVRGEL---------------REYWINDGIYGSMNCLLYDHAVITALPLACKSC-

----RSNPSCTG------LPKFRS---------------------TVFGPTCDALDTVLT

DYVLP-ELAVGDWLVFPNMGAYTAAAGSNFNGFSISDIRTYCAAS---------------

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63

-----------------------------------

>Prumnopitys_andina

------------------------------------------------------------

-----------------------------VLAAPGLKTRK---VATLRCRSQ--------

---EAINELAQSLIEKEG---------TNEPFYILDLGMVVELWQKWQQALPRVRAFYAV

KCNPEPVLLWALATLGAGFDCASRAEIEAVLGIG-VTPDRIIYANPCKAETQLKYAAKVG

VNLTTFDSTEEVDKVKNAHPRCSLVLRVRAPEDGD------ARCPLGPKYGA--LPEEVN

GLLQAAQRAGLNVAGVSFHVGSGAAN--ARVYNGAIAAVKGVFQAAA-RLGLPKFRILNI

GGGFTAG------PRFAEAAIMIRAALESYFPD-SSS---VSVIGEPGRYFAESAFTLAT

NVIGKRVRGDL---------------REYWINDGIYGSMNCLLYDHAVISALPLACASR-

----RSNPSCRG------LPKYRS---------------------TVFGPTCDALDTVLT

DHWLP-ELQVGDWLIFPNMGAYTAAAGSNFNGFSTSAISTYCAAS---------------

-----------------------------------

>Pilgerodendron_uviferum

------------------------------------------------------------

----------------------------VVMGAARLKGQK---VSTLRSRTQ--------

---EAVNELMQAIIEREE---------RNEAFYVLDLGVVYDLWQKWQESLPSVRPFYAV

KCNPNPILLNSLAALGAGFDCASRAEIEAVLSLG-VSADRIVYANPCKAETQLKYAAKVG

VNLTTFDSTEEVEKIRNAHPRCEVILRVKAQEDGG------ARCPLGSKYGA--LAEEIA

PLLQAAQRAGLDVAGVSFHVGSGAEH--ARAYTAAINAVKNTFETAS-KLGLPRLRIINI

GGGFTAG------PRFTEASGAVRAALNAYFSGHSTP---ISVIAEPGRYFAESAFSLAT

NIIGKRVRGEV---------------REYWINDGIYGSMNCLLYDHAVITAIPLACSSR-

----RFNPSCIG------IPKFRS---------------------TVFGPTCDALDTVLT

DHWLP-ELHVGDWLVFPNMGAYTAAAGSNFNGF---------------------------

-----------------------------------

>Taxodium_distichum

------------------------------------------------------------

----------------------------VVIGAAKLRGQK---VSTLRSRSQ--------

---EAVNELMQAIIEREG---------GNEAFYVLDLGVVVDLWQKWQEALPGVRPFYAV

KCNPEPVLLSSLATLGAGFDCASRAEIEAVLSLG-VSPDRIVYANPCKAETQLKYAAKVG

VNLTTFDSKEEVEKIRSSHPSCEVLLRVKGQEDGG------ARCPLGSKYGA--LAEEVR

PLLQAAQRADLTVAGVSFHLGSGAEH--ARAYTAAISAVKYVFETAS-SLGLPRLRIVNI

GGGFTAG------PRFTEASAAVRGALNAYFSGGSSG---ISVIAEPGRYFAESAFSLAT

NIIGKRVRGDL---------------REYWINDGIYGSMNCLIYDHAVITALPLACTSR-

----RLNPSCHG------LPKYRS---------------------TVFGPTCDALDTVLT

DHWLP-ELQVGDWLVFPNMGAYTSAAGSSFNGFSTSAICTYCAVS---------------

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64

-----------------------------------

>Diselma_archeri

------------------------------------------------------------

----------------------------VVMGAARLKGQK---VCTLRSRSQ--------

---EAVNELMQAIIERED---------RNEAFYVLDLGVVFNLWQKWQESLPNVRPFYAV

KCNPDPVLLNSLATLGAGFDCASRAEIDAVLSLG-VPAGQIVYANPCKAETQLRYAAKVG

VNLTTFDSAEEVEKIRTAHPRCEVILRVKAQEDGG------ARCPLGSKYGA--LAEEIG

PLLQAAQRAGLTVVGVSFHVGSGAEH--ARAYTAAINAVKNTFETAS-KLGLPRLRIINI

GGGFTAG------PRFTEASAAVRAALNAYFSG--QA---ISVIAEPGRYFAESAFSLAT

NIIGKRVRGDV---------------REYWINDGIYGSMNCLLYDHALITAIPLACSSR-

----PLNPSCHG------VPKFRS---------------------TVFGPTCDALDTVLT

DHWLP-ELHVGDWLVFPNMGAYTAAAGSNFNG----------------------------

-----------------------------------

>Pseudotsuga_menziesii

------------------------------------------------------------

-----------------------------VLAAPVLKSRK---VTVLRSRSQ--------

---EAVNEMAQSIIENED---------MNDPFYIEDVGVVVDLWQKWHEALPRVQPFYAV

KCNPDPILLSALATLGSGFDCASRAEIEAILKLG-VSPDRIVYANPCKAETQLKFAANVG

VNLTTFDSVEEVEKIKKFHPRCVLLLRVKVPEEDAAG----ARCPLGPKYGA--LPEEVG

PLLQAAQLSGLTVAGVSFHAGSGVAR--SRVYAGAVGAVRGIFDSAS-RLGLPQLRILNI

GGGFTAG------PIFTEAAGTVRTALKTYFTDETA----VSVIAEPGRYFAESAFSLAT

NVIGKRVRGEL---------------REYWINDGIYGSMNCLLYDHAVITALPLACKSH-

----RSNPSCTG------MPKYRS---------------------TVFGPTCDALDTVLT

DYFLP-ELAVGDWLVFPNMGAYTAAAGSNFNGFAISDIHTYCAAS---------------

-----------------------------------

>Pinus_ponderosa

------------------------------------------------------------

-----------------------------VLASAEVKSRK---VMALRSRSQ--------

---EAVKEMVQSIIDNDD---------VSDPFYVLDLGVVVDLWHKWQEALPTVCPFYAV

KCNPEPALLSALATLGSGFDCASRVEIEAILKLG-VSPDRIVYANPCKAVTHLKYAASVG

VNLTTFDSIQEVEKIKKFHPRCALLLRVKIPNEKAGG----ARIPLGRKYGA--LPEEVE

PLLQAAQGSGLAVHGVSFHVGSSVSR--SGIYASAIATVRDVFDSAS-RLGMPKLSIVNI

GGGFTAG------QLFAEAAHTVRKCLKTYFPDETK----IFAMGEPGRYFAASAFWLAS

CVIGKRVRGEV---------------REYWINDGIHGSMSCLIHDKAVITAFPLACKSN-

----RSNASCTG------LPRYPS---------------------TVFGPTCDASDIVLI

DYLLP-ELVVGDWLVFPNMGAYAAVIGTNFNGFSVSAIPTYCAAS---------------

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65

-----------------------------------

>Microcachrys_tetragona

------------------------------------------------------------

-----------------------------VLAAPGVKTRK---VSTLRCRSQ--------

---DAINELAQSIIEKEG---------TKEPFYILDFGMVVDLWQKWQEALPRVRPFYAV

KCNPEPALLSALATLGAGFDCASRGEIEAVLGLG-VSPDRIIYANPCKAETQLRYAAKVG

VNMTTFDSTDEVDKIKKSHPRCSLVLRVRAPEDGD------ARCPLGPKYGA--LPEEVT

PLLQAAKRAGLAVAGVSFHVGSGAGN--ARVYTGAIASVKEVFEAAA-RLGLPKLRIVNI

GGGFTAG------LRFAEAAATVRVALDSYFPD-SSS---VSVIGEPGRYFAELAFTLAT

NVIGKRVRGDL---------------REYWINDGIYGSMNCLLYDHAVIGALPLACASR-

----RSNPSCRG------LPKYRS---------------------TVFGPTCDALDTVLT

DHWLP-ELQVGDWLIFPNMGAYTAAAGSNFNGFSTSAICTYCAVS---------------

-----------------------------------

>Taiwania_cryptomerioides

------------------------------------------------------------

----------------------------VVMGAARLRGQK---VSTLRSRSQ--------

---EAVSELMQAIIEKER---------RNEAFYVVDLGVVVDLWHKWQEALPGVRPFYAV

KCNPEPVLLSALATLGAGFDCASQAEIEAVLSLG-VAADRIVYANPCKAETQLKYAAKVG

VNLTTFDSKEEVEKIKSSHPRCEVLLRVKAQEDGG------ARCPLGSKYGA--LPEEIG

PLLQAAHRAGLTVSGVSFHVGSGAEH--ARAYTGTIGTVRSAFETAQ-RLGLPRLRIVNI

GGGFTAG------PRFTEAAATVRAALNSYFPN-HSS---LSLIAEPGRYFAGSAFSLAT

NIIGKRVRGDV---------------REYWINDGIYGSMNCLLYDHAVITALPLACVSR-

----RLNPSCNG------LPKYRS---------------------TVFGPTCDALDTVLT

DFWLP-ELQVGDWLVFPNMGAYTAAAGSNFNGFSTSAICTYCAVS---------------

-----------------------------------

>Retrophyllum_minus

------------------------------------------------------------

-----------------------------VLAAPGLKTRK---VSTLRCRSQ--------

---EAIDELAQSIIEKEG---------IKEPFYILDLGMVVELWKKWQEALPRVRPFYAV

KCNPEPALLWTLATLGAGFDCASRVEIEAVLGLG-VSPDRIIYANPCKAETQLRYAAKVG

VNITTFDSTEEVDKIKKCHPRCSLVLRVRAPEDGE------ARCPLGPKYGA--LPEEII

PLLQAAKRAGLSVTGVSFHVGSGASN--ARVYNGAIKAVKGVFEAAA-RMGLPKLRVVNI

GGGFTAG------PRFSDVAATVQAALQSYFPD-SSS---VSVIGEPGRYFAESAFTLAT

NVIGKRVRGDL---------------REYWINDGIYGSMNCLVYDHAVIAALPLACASR-

----RSNPSCRG------LPKYRS---------------------TVFGPTCDALDTVLT

DHWLP-ELQVRDWLIFPNMGAYTAAAGSNFNGFSTSAICTFCAAS---------------

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-----------------------------------

>Austrocedrus_chilensis

------------------------------------------------------------

----------------------------VVMGAARLKGQK---VSTLRSRTQ--------

---ESVNELMQAIIEREE---------RKEAFYVLDLGVVFDLWQKWQESLPNVRPFYAV

KCNPDPILLNSLATLGAGFDCASRAEIEAVLSLG-VSADRIVYANPCKAETQLKYAAKVG

VNLTTFDSTEEVEKISNAHPRCEVILRVKAQEDGG------ARCPLGSKYGA--LAEEIG

PLLQAAQRAGLTVAGVSFHVGSGAEH--ARAYTGAINAVKNAFETAS-KLGLPRLKIINI

GGGFTAG------PRFTEASAAVRAALNAYFSGHSTA---ISVIAEPGRYFAESAFSLAT

NIIGKRVRGEV---------------REYWINDGIYGSMNCLLYDHAVITAIPLACSSR-

----RLNPSCNG------LPKFRS---------------------TVFGPTCDALDTVLT

DHWLP-ELHVGDWLVFPNMGAYTAAAGSNFNGF---------------------------

-----------------------------------

>Brugmansia_sanguinea

------------------------------------------------------------

--MAGQTIIVSGLNPAAILQSTIGGAPP---AAEAENGHT-RKVIPLSRD----------

----ALQDFMVSIITQKL-QDEKQ------PFYVLDLGEVVSLMDQWNTGLPNIRPFYAV

KCNPEPSFLSMLSAMGSNFDCASRAEIEYVLSLG-ISPDRIVFANPCKPEADIIFAAKVG

VNLTTFDSEDEVYKIRKHHPKCELLLRIKPMDDGN------ARCPMGPKYGA--LPDEVE

PLLRTAQAARLTVSGVSFHIGSGDAD--SKAYLGAIAAAKGVFETAA-RFGMSKMTVLDI

GGGFTSG------RQFTTASVAVRSALEQHFHDDRE----LTIIAEPGRFFAETAFTLAT

TIIGKRARGEL---------------KEYWINDGLYGSMNCVLYDHATVNATPLACMSN-

----RSNLTCGG-----SKT-FPS---------------------TVFGPTCDALDTVLR

DYQLP-ELQVNDWLVFPNMGAYTKAAGSNFNGFNTSAIVTHLAYAYPS------------

-----------------------------------

>Solanum_ptychanthum

------------------------------------------------------------

--MAGQTVIVSGLNPAAILQSTIGGATA---AAAAENGQN-RKIVPLSKD----------

----ALQDFMVSIITQKL-QDDKQ------PFYVLDLGEVVSLMEQWNSALPNIRPFYAV

KCNPEPSFLSMLSAMGSNFDCASRAEIEYVLSLG-ISPDRIIFANPCKPESDIIFAEKVG

VNLTTYDSEEEVYKIRKHHPKCELLLRIKPMNDGN------ARCPMGPKYGA--LPEEIE

PLLRTAQAARLTVSGVSFHIGSGDAD--STAYLGAIAAAKQVFETAN-QLGMPKMTVLDI

GGGFTSG------HQFTTAAPAVKSALETHFQNSSE----LTIIAEPGRFFAETAFTLAT

TIIGKRVRGEL---------------KEYWINDGLYGSMNCVLYDHATVTATPLACMSN-

----RNNLNCGG-----WKT-FPS---------------------TVFGPTCDALDTVLR

DYQLP-ELQVNDWLVFSNMGAYTKAAGSNFNGFNTSAIVTHLAYAYPN------------

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67

-----------------------------------

>Ipomoea_pubescens

------------------------------------------------------------

--MERQPIIVSGLNPGAILRSTVV--------APAEDRKR---FVPLSKD----------

----ALNDFIKSIVLKK--QEAKD------PFYVMDLGEVVSLMDKWTTAFPNVRPFYAV

KCNPEPSFLTVLAAMDCNFDCASRSEIDYVLSLG-VSPDRIVFANPCKPEADVVYAANVG

VNITTFDSEYEVEKIKRFHPTCDLFLRIKPVRDGN------ARCPMGPKYGA--LPEEVE

PLLLAARAARLNVTGVSFHIGSGDAE--AGAYRGAIAAARAVFDTAT-RLGLPKLQVLDI

GGGFTSG------QQFNDAVEAVNQSVQEFFGDEPG----LTIIAEPGRFFAETPFTLAA

TVIGKRVRGEL---------------REYWINDGLYGSMNCILYDHATVIATPLACASNP

----APGSICRE-----SKT-FAS---------------------TVFGPTCDALDTVLR

DYQLP-ELQVNDWLVFPNMGAYTKAAGSNFNGFNTSTILTHMAYAYP-------------

-----------------------------------

>Solanum_dulcamara

------------------------------------------------------------

--MAGQTVLVSGLNPAAILQSTIGGAP-------AENGHA-RKVVPLSRD----------

----ALQDFMVSIITQKL-QDEKQ------PFYVLDLGEVVSLMDQWNTALPNIRPFYAV

KCNPEPSFLSMLSAMGSNFDCASRAEIEYVLSLG-ISPDRIVFANPCKPESDIIFAEKVG

VNLTTYDSEEEVYKIRKHHPKCEVLLRIKPMNDGN------ARCPMGPKYGA--LPEEIE

PLLRTAQAARLTVSGVSFHIGSGDAD--SNAYVGAIAAAKQVFETAN-QLGMSKMTVLDI

GGGFTSG------HQFTIAAPAVKSALEQHFLNFPE----LTIIAEPGRFFAETAFTLAT

TVIGKRVRGEL---------------KEYWINDGLYGSMNCVLYDHAAVTATPLACMSN-

----RNNLNCGG-----SKT-FPS---------------------TVFGPTCDALDTVLR

DYQLP-ELQVNDWLVFPNMGAYTKAAGSNFNGFNTSAIVTHLAYAYPS------------

-----------------------------------

>Datura_metel

------------------------------------------------------------

--MAGQTIIVSGLKPAAILQSTIGGAPP---ASAAENGHT-RKVVPLSRD----------

----ALQDFMVSIITQKL-QDEKQ------PFYVLDLGEVVSLMDQWNTGLPNIRPFYAV

KCNPEPSFLSMLSAMGSNFDCASRAEIEYVLSLG-ISPDRIVFANPCKPEADIIFAAEVG

VNLTTFDSEDEVYKIRKHHPKCELLLRIKPMDDGK------ARCPMGPKYGA--LPDEIE

TLLRTAQAARLNVSGVSFHIGSGDAD--SKAYLGAIAAAKGVFETAA-RFGMSKMTVLDI

GGGFTSG------NQFTNASTAVRSALEQHFHDEQE----LTIIAEPGRFFAETAFTLAT

TIIGKRVRGEL---------------KEYWINDGLYGSMNCVLYDHATVNATPLACMSN-

----RSNLSCGG-----SKT-FPS---------------------TVFGPTCDALDTVLR

DYQLP-ELQVNDWLVFPNMGAYTKAAGSNFNGFNTSAIVTHLAYAYPS------------

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68

-----------------------------------

>Solanum_xanthocarpum

------------------------------------------------------------

--MAGQTVIVSGLNPAAILQSTFGGAP----AAAEENGHN-GKVVPLSRD----------

----ALQDFMVSIITQKL-QDEKQ------PFYVLDLGEVVSLMDQWKAALPNVRPFYAV

KCNPEPSFLSMLSAMGSNFDCASRAEIEYVLALG-ISPDRIVFANPCKPESDIIFAEKVG

VNLTTYDSEDEVYKIRKHHPKCELLLRIKPMNDGN------ARCPMGPKYGA--LPEEIE

PLLRIAQAARLTVSGVSFHIGSGDAD--STAYLGAIAAAKQVFETAA-QLGMPKMTVLDI

GGGFTSG------LQFTSAAPAVKSALETHFQNSPD----LTIIAEPGRFFAETAFTLAT

TIIGKRVRGEL---------------REYWINDGLYGSMNCVLYDHATVTATPLACMSN-

----RNNLNCGG-----SKT-FPS---------------------TVFGPTCDALDTVLR

DYQLP-ELQVNDWLVFPNMGAYTKAAGSNFNGFNTSAIVTHLAYAYPN------------

-----------------------------------

>Lycium_barbarum

------------------------------------------------------------

--MAGQTVIVSGLNPAAILG----GTPP----SVAENGTG--KIVPMSKE----------

----ALQDFMVSIITQKL-QEEKQ------PFYVLDLGEVVSLMEQWNSALPNIRPFYAV

KCNPEPSFLSMLSALGSNFDCASRAEIEYVLSLG-ISPDRIVFANPCKPESDIIFAAKVG

VNLTTYDSEDEVYKIRKHHPKSELLLRIKPMDDGN------ARCPMGPKYGA--LPEEVE

PLLRAAQAARLTVSGVSFHIGSGDAD--SNAYLGAIAAAKKVFATAA-EFGMSKMAVLDI

GGGFTSG------HQFTTAATAVRSALSQHFNEEPE----LTIIAEPGRFFAETAFTLAT

TIIGKRVRREL---------------REYWINDGLYGSMNCVLYDHATVTATPLACMSN-

----RNNLNCGG-----SKT-FPS---------------------TVFGPTCDALDTVLR

GYQLP-ELQVNDWLVFPNMGAYTKAAGSNFNGFNTSAIATHLAYAYPS------------

-----------------------------------

>Nicotiana_sylvestris

------------------------------------------------------------

------------------------------------------------------------

--------------------DEKQ------PFYVLDLGEVVSLMDQWKSALPNIRPFYAV

KCNPEPSFLSILSAMGSNFDCASRAEIEYVLSLG-ISPDRIVFANPCKPESDIIFAAKVG

VNLTTYDSEDEVYKIRKHHPKSELLLRIKPMLDGN------ARCPMGPKYGA--LPEEVD

PLLRAAQAARLTVSGVSFHIGSGDAD--SNAYLGAIAAAKEVFETAA-KLGMSKMTVLDV

GGGFTSG------HQFTTAAVAVKSALKQHFDDEPE----LTIIAEPGRFFAETAFTLAT

TIIGKRVRGEL---------------REYWINDGLYGSMNCVLYDHATVNATPLAVLSN-

----RSNVTCGG-----SKT-FPT---------------------TVFGPTCDALDTVLR

DYQLP-ELQVNDWLVFPNMGAYTKAAGSNFNGFNTSAIVTHLAYAYPS------------

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69

-----------------------------------

>Ipomoea_lindheimeri

------------------------------------------------------------

--MERQPIIVSGLNPAAILRSTVG--------APAEDRKR---FVPLSKD----------

----ALNDFIKSIVLKK--QEAKD------PFYVMDLGEVVSLMDKWTTAFPNVRPFYAV

KCNPEPSFLTVLAAMDCNFDCASRSEIDYVLALG-VSPDRIVFANPCKPEADVVYAANVG

VNITTFDSEYEVEKIKRFHPTCDLLLRIKPVHDGN------ARCPMGPKYGA--LPEEVE

PLLLAARAARLNVTGVSFHIGSGDAD--AGAYRGAIAAARAVFDTAT-RLGLPKLQVLDI

GGGFTSG------QQFNDAVEAVNQSVQEFFGDEPG----LTIIAEPGRFFAETPFTLAA

TVIGKRVRGEL---------------REYWINDGLYGSMNCILYDHATVTATPLGCASN-

-----PGSICRE-----SKT-FTS---------------------TVFGPTCDALDTVLR

DYQLP-ELQVNDWLVFPNMGAYTKAAGSNFNGFNASTILTHMVYAYPN------------

-----------------------------------

>Solanum_sisymbriifolium

------------------------------------------------------------

--MAGQTVIVSGLNPAAILQSTFGGAP-A--AAAEENGHT-RKVVPLSRD----------

----ALQDFMVSIITQKL-QDEKQ------PFYVLDLGEVVSLMDQWKAALPNIRPFYAV

KCNPEPSFLSMLSAMGSNFDCASRAEIEYVLSLG-ISPDRIVFANPCKPESDIIFAEKVG

VNLTTYDSEDEVYKIRKHHPKCELLLRIKPMNDGN------ARCPMGPKYGA--LPEEIE

PLLRTAQAARLTVSGVSFHIGSGDAD--STAYLGAIAAAKQVFETAA-QLGMPKMTVLDI

GGGFTSG------PQFTTAAPAVKSALETHFQNSPD----LTIIAEPGRFFAETAFTLAT

TIIGKRVRGEL---------------REYWINDGLYGSMNCVLYDHATVTATPLACMSN-

----RNNLNCGG-----SKT-FPS---------------------TVFGPTCDALDTVLT

DYQLP-ELQVNDWLVFPNMGAYTKAAGSNFNGFNTSAIVTHLAYAYPS------------

-----------------------------------

>Lycium_sp.

------------------------------------------------------------

--MAGQTVIVSGLNPAAILG----GTPP----SVAENGTG--KIVPMSKE----------

----ALQDFMVSIITQKL-QEEKQ------PFYVLDLGEVVSLMEQWNSALPNIRPFYAV

KCNPEPSFLSMLSALGSNFDCASRAEIEYVLSLG-ISPDRIVFANPCKPESDIVFAAKVG

VNLTTYDSEDEIYKIRKHHPKSELLLRIKPMDDGN------ARCPMGPKYGA--LPEEVE

PLLRAAHAARLTVSGVSFHIGSGDAD--SNAYLGAIAAAKKVFATAA-EFGMSKMTVLDI

GGGFTSG------HQFTTAATAVRSALSQHFNEEPE----LTIIAEPGRFFAETAFTLAT

TIIGKRVRREL---------------REYWINDGLYGSMNCVLYDHATVTATPLACMSN-

----RNNPNCGG-----SKT-FPS---------------------TVFGPTCDALDTVLR

DYQLP-ELQVNDWLVFPNMGAYTKAAGSNFNGFNTSAIATHLAYAYPS------------

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70

-----------------------------------

>Actinidia_chinensis

------------------------------------------------------------

--------LGSNN--LQTILS-----------AAVVREKS---VTTIHKD----------

----GLMDFIQSIIFNKPEL--------KEPFYVLDMGVVVSLMDTWTRNLPSICPFYAV

KCNPEPAFLGAMAALGAGFDCASQVEIETILSLG-VSPDRIIYANPCKAESHIKYAASVG

VNLTTFDSKEEVEKIRKYHPKCALLIRIKVDDNN-------AKWPLGGKFGA--LPEEFE

PLLLAARIAELAVCGVSFHVGSIVTD--SCTYRAAIAAAKTVFDMAI-RLGMPQLRMLNI

GGGFTVA------PQFEGSATIIKSALQEYFQHELG----LTIIAEPGRFFAETPFTLVA

TIIGKRVRGEL---------------REYWINDGVYGSLNYLLFDHASVDLMPLACTSN-

----SGNPTCQ-----GSR-TYVS---------------------TVFGPTCDAIDTIVR

GHQLP-ELQVNDWLVFKNMGAYTIAVGSNFNGFRASATKTHL------------------

-----------------------------------

>Lycopersicon_cheesmanii-1

------------------------------------------------------------

--MAGQTVIVSGLNPAAVLQSTFGGAPAA--AAAEENGHT-RKVVPLSRD----------

----ALQDFMVSIITQKL-QDEKQ------PFYVLDLGEVVSLMDQWKAALPNIRPFYAV

KCNPEPSFLSMLSAMGSNFDCASRAEIEYVLSLG-ISPDRIVFANPCKPESDIIFAEKVG

VNLTTYDSEDEVYKIRKHHPKCELLLRIKPMNDGN------ARCPMGPKYGA--LPEEIE

PLLRTAQAARLTVSGVSFHIGSGDAD--SSAYLGAIAAAKQVFETAA-QLGMPKMTILDI

GGGFTSG------PQFTTAAPAVKSALETHFQNYPD----LTIIAEPGRFFAETAFTLAT

TIIGKRVRGEL---------------REYWINDGLYGSMNCVLYDHATVTTTPLACMSN-

----RNNLNCGG-----SKT-FPS---------------------TVFGPTCDALDTVLT

DYQLP-ELQVNDWLVFPNMGAYTKAAGSNFNGFNTSAIVTHLAYAYPS------------

-----------------------------------

>Lycopersicon_cheesmanii-2

------------------------------------------------------------

--------------------------------------HT-RKVVPLSKD----------

----ALQDFMVSIITQKL-QDDKQ------PFYVLDLGEVVSLMEQWNSALPNIRPFYAV

KCNPEPSFLSMLSAMGSNFDCASRAEIEYVLSLG-ISPDRIVFANPCKPESDIIFAEKVG

VNLTTYDSEDEVYKIRKHHPKCELLLRIKPMNDGN------ARCPMGPKYGA--LPEEIE

PLLRTAQAARLTVSGVSFHIGSGDAD--SSAYLGAIAAAKQVFETAA-QLGMPKMTILDI

GGGFTSG------PQFTTAAPAVKSALETHFQNYPD----LTIIAEPGRFFAETAFTLAT

TIIGKRVRGEL---------------REYWINDGLYGSMNCVLYDHATVTTTPLACMSN-

----RNNLNCGG-----SKT-FPS---------------------TVFGPTCDALDTVLT

DYQLP-ELQVNDWLVFPNMGAYTKAAGSNFNGFNTSAIVTHLAYAYPS------------

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71

-----------------------------------

>Glycyrrhiza_glabra

------------------------------------------------------------

-----QP-----------------INLKSIFGASGVKGKR---VTTL--SSE--------

--KDGLSDFIQSITKDKTDIDIDIDDV-DTPFSVLDLGVVTALFENWTTKLPGVQPYYAV

KCNPNPSIIGTLAALGSSFDCASRNEIETVLSLG-VSPDRIIYANPCKSESHIRYAASVG

VNVTTYDSVEEIEKIRKWHPQCELLLRIKPAGDSG------ARTCLGLKYGA--LQEEVP

ELLRAADVAGLKVTGVSFHIGSGGGD--TRAYHGAIAMAKGVFETAS-RLGMPKMHVLDI

GGGFTSG------AQFDAAAVKVNAAIKSHFGGEED----LVVIGEPGRYFAETAFTLVT

RVIGKRVRGEM---------------REYWIDDGVYGTLNCIMFDFATVTCTPLRCASK-

----PENPTCRDD----NNKTYPS---------------------TVFGPTCDSLDTVLR

DYQLP-ELQVNDWLVFPNMGAYTTSSGTNFNGFSSSAKHTYLAYSSP-------------

-----------------------------------

>Linum_leonii

------------------------------------------------------------

--------IIT---------------------APGVKGRN---VTSLSNG----------

----GLTDFLRSIIIDKKDPDAGG-----EPFYVLDLGIVASLMDAWSKSLPMVHPFYAV

KCNPDKALLGTLAHLGASFDCASRAEIESVLAVG-VSPDKIVFANPCKPESHIKYAAAAG

VNLTTFDSVDELEKLSRLHPKCALLIRIKPPEDGG------ARCPLGPKYGA--LEDEIE

PLLISAQDLRLPVVGASFHIGSGATE--SGAYRGAIAAARSVFDTAT-RLGLPLMNMLDI

GGGFTSG------SQFEDAASEIRAALNDYFSDEPG----LKVISEPGRFLSESAFTLAA

TIIGKRVRGGE---------------REYWINDGLYGSMNCILYDHATVRCAPLALISN-

----PADPTCEV-----AAT-YSS---------------------TVFGPTCDALDTVFT

GRQLP-ELKVNDWLVFPDMGAYTAAAGSNFNGFNADRILTHLA-----------------

-----------------------------------

>Linum_usitatissimum-stem_region_3

------------------------------------------------------------

-------------------------------------------VTSLPDG----------

----ALTDFLRSIIKD---PDTAG-----EPFYVLDLGIIASLMDVWSKSLPIVQPFYAV

KCNPEKALLGTLAHLGASFDCASRAEIESVLSVG-VSPDKIVFANPCKPESHIRYAAAVG

VNLTTFDAVDELEKLSRLHPKCALLIRIKPPEDGG------ARCPLGPKYGA--LEDEIE

PLLQTAQSLRLPVVGASFHIGSGATE--SGAYRGAIAAARSVFDTAV-RLGMPRMHMLDI

GGGFTSG------SQFEDAATEIRAALDECFSGEPG----LKVISEPGRFFSESAFTLAA

TIIGKRVRGGQ---------------REYWINDGLYGSMNCILYDHATVRCAPLALISN-

----PGDPSCEV-----AAAKYSS---------------------TVFGPTCDALDTVFT

GRLLP-ELKVNDWLVFPDMGAYTAAAGSNFNGFSADRILTHLA-----------------

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72

-----------------------------------

>Thladiantha_villosula

------------------------------------------------------------

----------------------------LLQAAPGIKGST---LASISED----------

----GLLDFLQSIALNDN-EANEP-------FYVCDLAVVVDLMDHWSCSLPMVRPYYAV

KCNPQPALLGTMAALGSNFDCASRAEIQAVLALG-VSPDRIVFANPCKPESHIKYAASVG

VNLTTFDSVEEVDKIRRCHPDSALLLRIKGSDDGG------ARCPLGNKYGA--LPEEII

PLLEAAKAAELSVTGVSFHIGSGATQ--TGAYWATIAAAKGVFETAV-KLGMPPMNVLNI

GGGFTAG------SQFDEAAATVKAALQKYFPNEQN----LNIISEPGRFFAESAFTLAA

NIIGKRVRGEL---------------REYWINDGLYGSMNCILYDHATVTCTPMACTSN-

----RKNPVCGG-----ARK-YSS---------------------TVFGPTCDALDTVLT

GLQLP-ELQVNDWLVFPNMGAYTAAAGSSFNGFSTSAILTHLVYSN--------------

-----------------------------------

>Cannabis_sativa-4_samples_combined

------------------------------------------------------------

----------------------------LISGSPGVRGKK---VTPIDKHNN--------

----GLISFMQTIINDTQLQEQEP-------FYVLDLGVVVNLMDEWTRTLPTVKPFYAV

KCNPDQALLGAMAALGSGFDCASRAEIQTVLGLG-VSPAQIVFANPCKPEAHIKYAATVG

VNLTTFDSKDEVEKIRKWHPKCGLLIRIKAPDDGV------ARCPLGPKYGA--LPDEVE

PLLRAAQAAGLTVCGVSFHIGSGDTH--SGAYRGAIEAAKTVFETAA-RLGFQQMKVLNI

GGGFTSG------ETFEEAASNVRAALRTYFPNSQG----LSIIAEPGRFFGETAFTLAA

NVIGKRVRGDL---------------REYWINDGIYGSMNCLLYDHATLTCVPLACSSK-

----RANPTCEG-----EIT-YDS---------------------TVFGPTCDALDTVLT

GYRLP-ELEVNDWLLFTKMGAYTMAAGSNFNGFNTSAILTYLAYSD--------------

-----------------------------------

>Cannabis_sativa-stem_peel

------------------------------------------------------------

----------------------------LISGSPGVRGKK---VTPIDKHNN--------

----GLISFMQTIINDTQLQEQEP-------FYVLDLGVVVNLMDEWTRTLPTVKPFYAV

KCNPDQALLGAMAALGSGFDCASRAEIQTVLGLG-VSPAQIVFANPCKPEAHIKYAATVG

VNLTTFDSKDEVEKIRKWHPKCGLLIRIKAPDDGV------ARCPLGPKYGA--LPDEVE

PLLRAAQAAGLTVCGVSFHIGSGDTH--SGAYRGAIEAAKTVFETAA-RLGFQQMKVLNI

GGGFTSG------ETFEEAASNVRAALRTYFPNSQG----LSIIAEPGRFFGETAFTLAA

NVIGKRVRGDL---------------REYWINDGIYGSMNCLLYDHATLTCVPLACSSK-

----RANPTCEG-----EIT-YDS---------------------TVFGPTCDALDTVLT

GYRLP-ELEVNDWLLFTKMGAYTMAAGSNFNGFNTSAILTYLAYSD--------------

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73

-----------------------------------

>Linum_lewisii

------------------------------------------------------------

--------IIT---------------------APGVKGRN---VTSLSNG----------

----GLTDFLRSIIIDEKDPDAGG-----EPFYVLDLGIVASLMDAWSKSLPMVHPFYAV

KCNPDKALLGTLAHLGASFDCASRAEIESVLAVG-VSPDKIVFANPCKPESHIKYAAAAG

VNLTTFDSVDELEKLSRLHPKCALLIRIKPPEDGG------ARCPLGPKYGA--LEDEIE

PLLISAQDLRLPVVGASFHIGSGATE--SGAYRGAIAAARSVFDTAT-RLGLPRMNMLDI

GGGFTSG------SQFEDAASEIRAALNDYFSDEPG----LKVISEPGRFLSESAFTLAA

TIIGKRVRGGE---------------REYWINDGLYGSMNCILYDHATVRCAPLALISN-

----PADPTCEV-----AAT-YSS---------------------TVFGPTCDALDTVFT

GRQLP-ELKVNDWLVFPDMGAYTAAAGSNFNGFNADRILTHLA-----------------

-----------------------------------

>Linum_usitatissimum-3_samples_combined

------------------------------------------------------------

--------IIT---------------------APGVKGRT---VTSLPDG----------

----ALTDFLRSIIKD---PDTAG-----EPFYVLDLGIIASLMDVWSKSLPIVQPFYAV

KCNPEKALLGTLAHLGASFDCASRAEIESVLSVG-VSPDKIVFANPCKPESHIRYAAAVG

VNLTTFDAVDELEKLSRLHPKCALLIRIKPPEDGG------ARCPLGPKYGA--LEDEIE

PLLQTAQSLRLPVVGASFHIGSGATE--SGAYRGAIAAARSVFDTAV-RLGMPRMHMLDI

GGGFTSG------SQFEDAATEIRAALDECFSGEPG----LKVISEPGRFFSESAFTLAA

TIIGKRVRGGQ---------------REYWINDGLYGSMNCILYDHATVRCAPLALISN-

----PGDPSCEV-----AAAKYSS---------------------TVFGPTCDALDTVFT

GRLLP-ELKVNDWLVFPDMGAYTAAAGSNFNGFSADRILTHLA-----------------

-----------------------------------

>Cannabis_sativa-stem

------------------------------------------------------------

----------------------------LISGSPGVRGKK---VTPIDKHNN--------

----GLISFMQTIINDTQLQEQEP-------FYVLDLGVVVNLMDEWTRTLPTVKPFYAV

KCNPDQALLGAMAALGSGFDCASRAEIQTVLGLG-VSPAQIVFANPCKPEAHIKYAATVG

VNLTTFDSKDEVEKIRKWHPKCGLLIRIKAPDDGV------ARCPLGPKYGA--LPDEVE

PLLRAAQAAGLTVCGVSFHIGSGDTH--SGAYRGAIEAAKTVFETAA-RLGFQQMKVLNI

GGGFTSG------ETFEEAASNVRAALRTYFPNSQG----LSIIAEPGRFFGETAFTLAA

NVIGKRVRGDL---------------REYWINDGIYGSMNCLLYDHATLTCVPLACSSK-

----RANPTCEG-----EIT-YDS---------------------TVFGPTCDALDTVLT

GYRLP-ELEVNDWLLFTKMGAYTMAAGSNFNGFNTSAILTYLAYSD--------------

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74

-----------------------------------

>Linum_hirsutum

------------------------------------------------------------

--------LIT---------------------TPGVKGRT---VTSLSNG----------

----GLTHFLHSIITDDANSGGGG-----EPFYVLDLGTVASLMAAWSKSLPMVHPFYAV

KCNPEKALLGTLAHLGASFDCASRAEIESVLSVG-VSPDKIVFANPCKPESHIAYAAAAG

VNLTTFDSVDELEKMSRLHPDCALLIRFKPPEGGG------ARCPLGPKYGA--LDDEIE

SLLTTAQSLRLSVVGASFHIGSGATE--SGAYRGAIAAARSVFDAAS-RLGLPEMQKLDI

GGGFTSG------AQFEAAAVEIRAALDDYFPDQPG----LIVIGEPGRFFAESACTLAA

AIIGKRVRGGQ---------------REYWINDGLYGSMNCILYDHATIRCAPLAVVSN-

----PVDPTCEA-----GPT-YSS---------------------TVFGPTCDALDTVFT

GRQLP-ELKVNDWLVFPDMGAYTAAAGSNFNGFNADRISTHLA-----------------

-----------------------------------

>Cannabis_sativa-core

------------------------------------------------------------

----------------------------LISGSPGVRGKK---VTPIDKHNN--------

----GLISFMQTIINDTQLQEQEP-------FYVLDLGVVVNLMDEWTRTLPTVKPFYAV

KCNPDQALLGAMAALGSGFDCASRAEIQTVLGLG-VSPAQIVFANPCKPEAHIKYAATVG

VNLTTFDSKDEVEKIRKWHPKCGLLIRIKAPDDGV------ARCPLGPKYGA--LPDEVE

PLLRAAQAAGLTVCGVSFHIGSGDTH--SGAYRGAIEAAKTVFETAA-RLGFQQMKVLNI

GGGFTSG------ETFEEAASNVRAALRTYFPNSQG----LSIIAEPGRFFGETAFTLAA

NVIGKRVRGDL---------------REYWINDGIYGSMNCLLYDHATLTCVPLACSSK-

----RANPTCEG-----EIT-YDS---------------------TVFGPTCDALDTVLT

GYRLP-ELEVNDWLLFTKMGAYTMAAGSNFNGFNTSAILTYLAYSD--------------

-----------------------------------

>Erythroxylum_coca

------------------------------------------------------------

-----------------MGSNARNLQA--VLGAPGVRGRR---VAALPKD----------

----GLTDFMQSIIMKRN-ESKEP-------FYVLDLGVVSGLMDKWSRTLPMVRPFYAV

KCNPEPALLGSLAAMGANFDCASRAEIEAVLSLG-VSPDRIVYANPCKQESHIKYAASVG

VNLTTFDSKDELEKMRKWHPKCALLLRVKAPEDGG------ARCPLGPKYGA--LPEEVI

PLLQAAQAARLSVVGASFHIGSGATH--FSSYRGAIVEAKKAFETAV-KMGMPRMTMLNI

GGGFTAG------SQFDEAATAIKSALQTYFPNEPG----LTIISEPGRFFAESTFTLAT

NVIGRRVRGEL---------------REYWINDGIYGSMNCILYDHATVTCKPLACTSS-

----RANPMCKG-----ARV-YNS---------------------TVFGPTCDALDTVMA

GHLLP-DLQVSDWLVFPNMGAYTAAAGSSFNGFKTAAILTYLAYSN--------------

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75

-----------------------------------

>Linum_grandiflorum

------------------------------------------------------------

--------IIT---------------------APGVKGRS---VTSLSDG----------

----ALTDFLRSIIKD---SDTGG---EPEPFYVLDLGIVDSLVDAWSKSLPMVHPFYAV

KCNPEKALLGTLAHLGASFDCASRAEIESVLSVG-VSPDKIVFANPCKPESHIQYAAAVG

VNLTTFDSVDELEKLSRLHPKCALLIRIKPPEDGG------ARCPLGPKYGA--LDEEIE

PLLVTAQSLRLPVVGVSFHIGSGATE--SGAYQGAIAAARSVFDTAI-RLGLPRMHMLDI

GGGFTSG------SQFEDAATEIRAALDDYFSEEPG----LKVISEPGRFFSETAFTLAA

TIIGKRVRGGQ---------------REYWINDGLYGSMNCILYDHATVRCAPLAFISN-

----PGDPTCQV-----PAT-YSS---------------------TVFGPTCDALDTVFT

GRLLP-DLKVNDWLVFPDMGAYTAAAGSNFNGFNADRILTHLAYS---------------

-----------------------------------

>Stangeria_eriopus

------------------------------------------------------------

--------------------------------APVVKGRR---VAILKRRSQ--------

---DAVNQLMQSIIEKQGG--------LQDPFYVVDLGVVVDLWEKWQEGLPRVRPFYAV

KCNPEPAFLGALSAMGAGFDCASRAEIEAVLSLG-VSADRIVYANPCKAESQLRYAARVG

VNMTTFDSREEVDKISKCHPRCALLLRVRALQEER------ARCPLGPKYGA--LPEEVS

GLLQSAHQAGLAVAGVSFHVGSGVSQ--SVAYENAIAAVRGVVEAAS-RLGLPPLRVLNI

GGGFTSG------PRFAEAAAVIRSSLQTYFPQEEGGQG-VRVMAEPGRYFAESAFWLAT

TVIGKRVRGEV---------------REYWINDGIYGSMNCLLYDHALITALPLACTSR-

----PHDPSCNG------LPRFPS---------------------TVFGPTCDALDTVLT

DHLLP-DLSVGDWLVFPNMGAYTAAAGSNFNGFSTSAIRTYCAIS---------------

-----------------------------------

>Encephalartos_barteri

------------------------------------------------------------

--------------------------LRRVIAAPVVKGRK---VAALKRRSQ--------

---EAVNQLMQSIIEKQG---------LQDPFYVLDLGVLVNLWEQWQEELPRVRPFYAV

KCNPEPAFLGALSALGAGFDCASRAEIEVVLSLG-VSADRIVYANPCKAETQLKYAARVG

VNMTTFDSKEEVEKIKKSHPRCVLLLRERALEEER------ARCPLGPKYGA--LPDEVS

GLLRCAQQAGLTVAGVSFHVGSGVAV--ASAYDSAIAAVRGVFDTAS-RLGLPRLRILNI

GGGFTSG------LRFAEAAATIRRSLETYFPDEED----VSVMAEPGRYFAESAFSLAT

NVIGKRVRGEV---------------REYWINDGIYGSMNCLVYDHALISALPLACTSH-

----PADPSCNG------LPEFRS---------------------TVFGPTCDALDTVLT

DHFLP-DLSVGDWLVFPNMGAYTVAAGSNFNGFSTSAIRTYCAASMP-------------

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76

-----------------------------------

>Tmesipteris_parva

------------------------------------------------------------

------------------------------------------------------------

-----MDAFIAKKILSSG---------QEDAFYVLNLGVLLCLWNSWKLAMPRVHPFYAV

KCNYDGALLAVLAALGVGFDVASKSEIEMVRKLG-VSHDRIIFANPCKLPSHIATASKYG

IHLTTFDSKMELLKLEKCNPQAELVLRIRVCDAAA-------RCPLGVKYGAE--MDECE

PLLIAAQHFGLQVVGVSFHVGSGALD--AAPFAIAIKQARRVFDMAS-TLGLVPFRLLDI

GGGFVSEG--GNGVKFSVVASVINEALDEYFP--PSMG--VTIIAEPGRFFAEEPFTLVT

QIFGSRIRTKM--GTE---------MAEYWVNDGIYGSMNCIFYDHATLTVRAIPLFSS-

-----VKDRG-D-------SGCKA---------------------TIFGPTCDGLDLIMD

NVSLP-RLQCGDWLLFPRMGAYTKVAGSSFNGFDVED-----------------------

-----------------------------------

>Sceptridium_dissectum

------------------------------------------------------------

------------------------------------------------------------

-----MDAFIRRKILYTG---------AENAFYVMDLGTLFMLWKKWKSTLPRVHPFYAV

KCNSDGVLLALLAALGAGFDVASKMELDTVRSLG-VSGDRIIFANPCKLPSHIADAAKHN

VFLTTFDSEIELFKLRKFNPKAEVVVRIRVCDPGA-------RCPLGIKYGAE--IDECG

NLLEAARKLGFQVVGVSFHVGSGASD--PSSFTEGILQARKVFDIAA-TLGLAPLRLLDI

GGGFVSDG--GNGVNFSAAAAAINEALERYFP--LTTG--VTIIAEPGRFFAEEPFTLAA

QVFGSRARRKE--GLE---------LAEYWVNDGIYGSMNCLLYDHATLSVRALPVTSVK

-----VDDER-M-------DGCQS---------------------IIFGPTCDGLDKIME

NVWLP-RLQWGDWLLFPRLGAYTKAAGSSFNGFDVNDILTSYV-----------------

-----------------------------------

>Psilotum_nudum

------------------------------------------------------------

------------------------------------------------------------

-----MDSFISKKILSSG---------QEDAFYVLNLGVLLHLWKTWKLAMPRVHPFYAV

KCNDDGALLAVLAALGAGFDVASKSEIESVRRLG-VSHDRIIFANPCKLPSHIATASKYG

IHLTTFDSKTELLKLEKCNPQAKLVLRIRVCDAAA-------RCPLGVKYGAE--MDECE

PLLTAAQNFGLQVVGVSFHVGSGALD--AAPFAIAIKQARRVFDMAS-TLGLVPLRLLDI

GGGFVSEG--GNGVTFSVVASVVKEALDEYFP--PSMG--VTIIAEPGRFFAEEPFTLAT

QIFGSRMRMKM--GTE---------MAEYWVNDGIYGSMNCLFYDHATLTVRAIPLCSS-

-----MKERG-D-------GGCKA---------------------TIFGPTCDGLDLIMD

NVSLP-RLQCGDWLLFPRMGAYTKVAGSSFNG----------------------------

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77

-----------------------------------

>Papaver_somniferum-leaf

------------------------------------------------------------

-----------------------------ILGAPGVKGKR---VMNNSSTDG--------

-----VTDFIHSIISTTKQE-------VKDPFYVLDLGKIVTLMDKWNHSLPSVKPFYAV

KCNPEPALLGTLALLGANFDCASKGEIETVLALG-VSPDRIVYANPCKSESHIKYAATVG

VNLTTFDSIDEVEKMRKFHPKCGLLMRIKAPEDEG------ARCPLGDKYGA--LPEEFV

PLLEAANAANLVVHGVSFHVGSGATH--SRAYRAAIAEAKAIFNTAE-KLGIAKMHILNI

GGGFTLG------SQFDDAAITIKNALETYFPDDQE----LMLISEPGRFFAETAFTLVT

DIIGKRVRGEL---------------REYYISDGIYGSMNCLLYDHATVTAKPLAYTSN-

----PEDPNCAG------LKTYTS---------------------TVFGPTCDGLDTLLT

NYQLP-DLKVNDWLVWPDMGAYTASAGSSFNGFNTSAIPTYLAYSIPN------------

-----------------------------------

>Eschscholzia_californica-5_samples_combined

------------------------------------------------------------

-----------------------------ILGAAGVKGRK---VITLSSNED--------

-----FKEFIQSIAISKNQEEV-----NEYPFYVLDLGKVVSLMNQWKSSLPIVRPFYAV

KCNPEPALLGLLALLGAGFDCASKAEIEAVLSLG-VSPDRIVYANPCKHESHIRYAANVG

VNLTTFDSLDEVEKIKKFHPKSALLLRIKAPDDEG------ARCPLGPKYGA--LTHEVT

PLLKAAQNAGLAVHGVSFHVGSGATH--SRAYRAAIEEAKLVFDTGT-KLGMARMHVLNI

GGGFTVG------PQFDEAAITIKTALENHFHGEQG----LMVISEPGRFFSETAFTLVT

TIIGKRIRGDL---------------REYYINDGIYGSMNCLLYDHATIKAMPLACSSN-

----PTNPTCS-------IKSYKS---------------------TVFGPTCDALDTLLI

GYELP-ELEVNDWLVWPSMGAYTAAAGSSFNGFNTSAIPTYLAYSS--------------

-----------------------------------

>Argemone_mexicana-root

------------------------------------------------------------

-----------------------------ILGAPGVKGKR---VMN-TSTDG--------

-----VTDFIQSIISTKKQE-------VKDPFYVLDLGKIVTLMNEWSHSLPNVKPFYAV

KCNPEPALLGTLALLGADFDCASKPEIEAVLSLG-VSPDRIVYANPCKSESHIKFAASVG

VNLTTFDSLEEIEKIRKFHPKCALLLRIKAPDDEG------ARCPLGQKYGA--LPEEVI

PLLKSANAAKLSVHGVSFHVGSGATH--SRAYGGAIAEAKSVFDTAI-ELGMPQMHVLNI

GGGFTVG------SQFDDAAITIKTALETHFPNDKG----LMFISEPGRFFAETAFTLVT

DIIGKRVRGDL---------------REYYISDGIYGSMNCLLYDHATITAKPLAYTSN-

----PSNPNCRG------MKTYTS---------------------TVFGPTCDGLDTLLT

DYELP-DLKVNDWLVWPDMGAYTASAGSNFNGFNTSAIPTYLAYS---------------

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-----------------------------------

>Ceratocapnos_vesicaria

------------------------------------------------------------

------------------------------------------------------------

------------------------------PFYVLDLGKVVSLMDKWYCSLPNVRPYYAV

KCNPDPSLLGTLAVLGANFDCASKAEIEVVLSLG-VSPDRIVYANPCKAESHIRYAAQVG

VNLTTFDSQEEVEKIRSLHPKCALLLRIKAPEDEG------VRCPLGSKYGA--LPEEVI

PLLQAADAAKLAVIGVSFHVGSGATH--SRAYCGAIETAKEVFDTAL-RLNMPPMHVLNI

GGGFTAG------PLFDNAAVTIKTALQAYFPNDQG----LSFISEPGRFFAETAFTLAT

NIIGRRVRNKL---------------REYWINDGIYGSMNCVLYDHATVTSTPLAYSSN-

----QANPTCQG------LKTYPS---------------------TVFGPTCDALDTVLT

DYQLP-ELQVKDWLVFPNMGAYTAAAGSNFNGFNISAISTHIVYSN--------------

-----------------------------------

>Corydalis_linstowiana

------------------------------------------------------------

-------------------------------GVPGVKGRK---VIG-LSKDG--------

-----LVDLLMSIISKNQEL--------QDPFYILDLGKVVSLMDKWFCSLPNVRPYYAV

KCNPDPSLLGTLAVLGANFDCASKAEIEAVLSLG-VSPDRIVYANPCKSEPHIRYAAQVG

VNLTTFDSQGEIEKIRRLHPKCALLLRIKAPEDEG------VRCPLGPKYGA--LPEEVT

PLLQAADEAKLAVVGVSFHVGSGATR--SRAYFGAIETAKEVFDTAL-RLNMPPMHVLNI

GGGFTAG------PLFDDAAVTIRDALQAYFPNDQG----LTFISEPGRFFAETSFTLAT

NIIGKRVRDKL---------------REYWINDGIYGSMNCILYDHATVTATPLAYSSN-

----QANPTCHG------LKTYPS---------------------TVFGPTCDALDTVLT

DYQLP-ELQMNDWLVFPNMGAYTAAAGSNFNGFNISAISTHIAYSN--------------

-----------------------------------

>Chlorokybus_atmophyticus

------------------------------------------------------------

------------------------------------------------------------

------DRFAKSCIVEQD---------LQETFYVMDLGAVERRWAEWTRLLPRVQAYYAV

KCNPDNALLAVLAAQGAGFDVASKAELCKVMQLG-VTSDRIVFSNPCKLPAHIAHAAAAG

VHLMSFDAESELHKVKVSDPNARMLLRIRADDKHA-------RCPLGVKYGAE--LAEVE

HLLRTAQHLGVRVEGVDFHVGSGASD--PGAFSAAIEAARHVFELAE-QLGLPQMTVLDI

GGGFSGGGIADG-LSFADVAHAINVALDLHFP--TSSG--VRVIAEPGRFFAESAAALAS

NIFGTRLRRSNSGER----------VQEYWISDGLYGSMNCLLYDHATLFVRPL-QPHGD

TATG--------------SKLYRS---------------------TVFGPTCDGLDTVLK

DTWLP-QLACEDWLMFSDMGAYTMAAGSNFNGFDSTAAPVFYV-----------------

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-----------------------------------

>Klebsormidium_subtile

------------------------------------------------------------

------------------------------------------------------------

-----VDKYAQNVIKQNG---------QEAPFMMFDLGMVARLYDAWKTTMPRVEPFYAV

KCNGDPALLSVLAALGSGFDCASLAEMQAVAAAG-VAPERIIYANPCKLESHLRHAVSAG

VNLTVFDAEDELYKIKKVHPGTELLLRIRADDVGA-------QCPLGSKYGAE--FDECE

PLLRAAKRLGLKCVGVSFHVGSGAAS--AQSFVEAIKAAKAVFEMAE-ALGMPKMSVLDI

GGGFSVGG----KLTFSAAGAAINKALEKFFP--EEEG--VKVIAEPGRYFAEAPAPLAA

LVFGRRLRGLRHAHTK---------ANEYYINDGVYGSMNCLLYDHATISARPLRVSGGL

-------RLLDE-------KMYRS---------------------TVFGPTCDGLDQVLT

DVWLP-KLEVGDWLLFPNMGAYTLAAGTSFNGFATSDIKTHYV-----------------

-----------------------------------

>Mesostigma_viride

------------------------------------------------------------

------------------------------------------------------------

-----LDQFIADQVEAEG---------LEESFYVCDLGHVVQRYQTWHKNLPRVHAFYAV

KCNPDAALVATLASQGAGFDCASLAEMKQVLSTG-VPPSLIIFANPCKMVSHIAFARDHG

VQYMTFDSVCELKKVKAIHPTAKMVLRIRADDRSA-------RCPLGVKYGAE--DDEHE

RLLQACLDLDVDIVGISFHVGSGSCN--ADAFLHAIRKARHTFDLAE-RLGLPPMTILDL

GGGFSGGGRASGGASFAVVASVINSAIDEYFPQGNADS--VRLIAEPGRFFAESSSHLAC

NVFGRRIRAHSKAERA---------THEYWVSDGMYGSMNCVMYDHSTLFARPIRLPKAL

SADGRRLPATCPS-----GSMHLS---------------------TVFGPTCDGLDQVLS

DYWLP-DLEIGDWLVFTDMGAYTMSAGSNFNGF---------------------------

-----------------------------------

>Spirogyra_sp.

------------------------------------------------------------

------------------------------------------------------------

------DQFIRNVINSSG---------IEDPFYVMDLSNVVQLWNTWKKALPRVRPFYAV

KCNPEPVLLSLLASLGAGFDVASKSEIEAVQPHG-VSPDRMIFANPCKLPSHMKFASSNN

VSLTTFDSESELVKFKNFYPGVNAVLRLRADDRGA-------RCPLGVKYGAE--FEDCQ

RLILLAKDMGINVAGVAFHVGSGASD--PESYVDGILAARSLFDMAV-SYGMPPMWLLDI

GGGFTSSG--GSGASFSLSASVINSALDRYFP--EDME--VSIIGEPGRFFAEAPFTLAT

HVFGTRIRGDS--HEP---------TPEYWINDGLYGSMNCLLYDHAELTVRPLRKNPE-

------DEFLSD-------QNYKS---------------------TVFGPTCDGLDTVMR

DVWLP-RLHCGDWLIFPRMGAYTQAAGSSFNGF---------------------------

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80

-----------------------------------

>Cylindrocystis_brebissonii-M2213

------------------------------------------------------------

------------------------------------------------------------

-----VDKLISTVVRETE---------MEEPFYVFDLGVVARLYRTWVMAMPRVLPFYAV

KCNPDPALLALLASLGTGFDVASKAEMEAVQAIGGVSAERMIYANPCKLPSHISFAAKAN

VRMTTFDSVSELKKLKKHHPSAEAVLRLRADDKGA-------RCPLGVKYGAD--MEECQ

ELLLAAKELGVRVAGVAFHVGSGASD--PSSFADGIEAARSLFEFAT-SLGMARMTLLDI

GGGFTSKG--GGGVQFAAAAAAVNEALDKFFP--EEMG--VRIIGEPGRFFAESPATLAT

HVFGTRFKGKG--PNK---------KGEYWINDGIYGSMNCLLFDHAELSTRPLSAPAKQ

RADGSAATWVGE-------RLYKS---------------------TVFGPTCDGLDTVLR

DIWLP-ELECGDWLVFPRMGAYTQAAGSSFNGFRTDDIRTVYVY----------------

-----------------------------------

>Mesotaenium_endlicherianum

------------------------------------------------------------

------------------------------------------------------------

-----MDACIRKQVTSTG---------AEEPFYVMDLGVVLRLWKTWTSAMPRVQPFYAV

KCNPDPALLSLLAALGAGFDVASKSEITAVVTRG-VSSERMIYANPCKLPSHITAAAKDG

VLRTTFDSESELVKLKKYHPGAHAVLRLRADDRGA-------RCPLGVKYGAE--LEECE

HLLKVAQSLGIHVAGVAFHVGSGAAD--SQSYTDGIETVRSLFDMAE-ALGMAPMTLLDI

GGGFTSKG--GSGMGFAQAATAINEALDEYFP--ESMG--VQIIGEPGRFFAEAPSTLAT

HVFGTRFRGKG--HAR---------KAEYWINDGIYGSMNCLLYDHAELTARPLMVASAG

AGAKGGASWLSQ-------KMLPS---------------------TIFGPTCDGLDTVLR

DVCLP-QLECGDWLVFPRMGAYTQAAGTSFNGFDTKDIRTVYVY----------------

-----------------------------------

>Entransia_fimbriat

------------------------------------------------------------

------------------------------------------------------------

-----IDQLARKFITHQG---------QEAAFMVMDLGLVPQLMAVWKATMPRVKPCYAV

KCNPNPGLLRIMASLGAGFDCASKAEIDMVQELG-VCGSQIIYANPCKLPSHIRHASICG

VDLTVFDSEDELHKLKKLHPLTRLLLRIRADDQGA-------QCPLGVKYGAE--LEECM

HLLQVAHSLGLSCVGVSFHVGSGASD--ARSFMRAIESARGVFDMAE-GLGMPKMTILDL

GGGFSVSG----CLPFGEAGAAINKALARFFP--AEGE--VSVIAEPGRYFAEATSTLAT

LVFGRRLH--PGSHGR---------PNEYYVNDGVYGSMNCILYDHAKVTARTLSRVHGQ

-------SQLEE-------QVYLS---------------------TVFGPTCDGLDTVLS

QVWLP-KLEVGDWLMFPNMGAYTLAAGSSFNGFSTSDIKTLYV-----------------

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81

-----------------------------------

>Mougeotia_sp.

------------------------------------------------------------

------------------------------------------------------------

-----VDSFISAVVDEWQ---------TEDPFYVMDLGVVLRLWQTWKTAMPRVTPFYAV

KCNPDAALLSLLGALGSGFDVASKAEIEAVLSLG-IESDRMIFANPCKLPSHIRFAGQEG

VNYTTFDSESELIKLKKLNPSAKAVIRLRADDRGA-------RCPLGVKYGAE--FEDCR

ELLMAAKRLQVEVAGVAFHVGSGASD--PCSFADGIEAAKALFDMAE-ELGMPRMNLLDV

GGGFTSNG--GQGVAFSVAAKAINEALDIHFP--EYSG--VRIIGEPGRFFAEAPSTLAT

HVFGTRFRGKG--LNR---------KSEYWINDGLYGSMNCLLYDHAELTTRPLAAPGKQ

RGS-QDKAWLGE-------KLYKS---------------------TVFGPTCDGLDTVLR

DVWLP-ELECGDWLVFPRMGAYTQAAGSSFNGFSTAD-----------------------

-----------------------------------

>Cylindrocystis_cushleckae

------------------------------------------------------------

------------------------------------------------------------

------DKFITAVVDASG---------TEEAFYVVDLGVVLRLWKTWTQAMPRVTPFYAV

KCNPDRALLTLLASLGTGFDVASKAELEAVVELG-VSPDRIIYANPCKLPGHIAAAAREG

VHYTTFDSESELQKLKKINPNAQAVLRLRADDRGA-------RCPLGVKYGAE--LEDCE

ELLLAAKKLGVNVAGIAFHVGSGAAD--PASYADGISAARSLFTLAE-NLGMPTMKLLDI

GGGFTSKG--GHGVGFSAAAAAINDALDEHFP--ESMG--VRIIGEPGRFFAEAPATLAT

HVFGTRFRGKG--LNR---------KCEYWINDGLYGSMNCLLYDHAELTTRPLAAPGKQ

RSA-SGNPWVGE-------KLYQS---------------------TIFGPTCDGLDTVMR

DTWLP-HMEMGDWLVFPRMGAYTQAAGSSFNGFSTADIKTLYVY----------------

-----------------------------------

>Leiosporoceros_dussii

------------------------------------------------------------

------------------------------------------------------------

------DQFIRNIINSSG---------IEDPFYVMDLSNVVQLWNTWKKALPRVRPFYAV

KCNPEPVLLSLLASLGAGFDVASKSEIEAVQPHG-ISPDRMIFANPCKLPSHMKFASSNN

VSLTTFDSESELVKFKNFYPGVNAVLRLRADDRGA-------RCPLGVKYGAE--FEDCQ

RLILLAKDMGINVAGVAFHVGSGASD--PESYVDGILAARSLFDMAV-SYGMPPMWLLDI

GGGFTSSG--GSGASFSLSASVINSALDRYFP--EDME--VSIIGEPGRFFAEAPFTLAT

HVFGTRIRGDS--HEP---------TPEYWINDGLYGSMNCLLYDHAELTVRPLRKNPE-

------DEFLSD-------QNYKS---------------------TVFGPTCDGLDTVMR

------------------------------------------------------------

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82

-----------------------------------

>Anthoceros_formosae

------------------------------------------------------------

------------------------------------------------------------

------DQFIRNVINSSG---------IEDPFYVMDLSNVVQLWNTWKKALPRVRPFYAV

KCNPEPVLLSLLASLGAGFDVASKSEIEAVQPHG-ISPDRMIFANPCKLPSHMKFASSNN

VSLTTFDSESELVKFKNFYPGVNAVLRLRADDRGA-------RCPLGVKYGAE--FEDCQ

RLILLAKDMGINVAGVAFHVGSGASD--PESYVDGILAARSLFDMAV-SYGMPPMWLLDI

GGGFTSSG--GSGASFSLSASVINSALDRYFP--EDME--VSIIGEPGRFFAEAPFTLAT

HVFGTRIRGDS--HEP---------TPEYWINDGLYGSMNCLLYDHAELTVRPLRKNPE-

------DEFLSD-------QNYKS---------------------TVFGPTCDGLDTVMR

DVWLP-RLHCGDWLIFPRMGAYTQAAGSSFNGF---------------------------

-----------------------------------

>Adiantum_tenerum

------------------------------------------------------------

------------------------------------------------------------

-----LDNFIRKKIVRSK---------VEDAFYVMDVGVVLRLWRTWKLAMPRVHPFYAV

KCNSDVSFLALLSSLGAGFDVASKAELDLVRSLG-VGGDRIIFANPCKLPSHILHAANSD

VHLTTFDSEGELFKLHKLNPQAEVVLRIRVCDAGA-------RCPLGVKYGAE--MEDCE

SLLHVAKNLGLKVVGIAFHVGSGASD--PSSFVQGIAEARHLFDVAK-VMGLMSLRLLDI

GGGFVSDG--GLGVLFSAAAASINDAIDKFFP--PSFG--VTIIAEPGRFFAEESFTLAA

QIFGSRIRHRD--GLK---------VSEYWINDGIYGSMNCLLYDHATLSVHGLQMCG-G

-----GDFNSSD-------DGCQS---------------------TIFGPTCDGLDTVMR

NVRLP-PMGCGDWLVFPRMGAYTKAAASSFNGFDI-------------------------

-----------------------------------

>Polypodium_glycyrrhiza

------------------------------------------------------------

------------------------------------------------------------

-----LDEVIKKQILNTR---------TEDAFYVMDIGVLLRLWKKWRFSLPRVHPFYAV

KCNSDRMILAILAALGAGFDVASKVELDMVRDLG-VGGDRIIFANPCKLPSHIQHARNHD

VHLTTFDSESELYKLHRMNPRAEAVLRIRVCDAGA-------RCPLGVKYGAE--MSECE

SLLLVAKGLGLTVVGVAFHVGSGASD--PSSFAQGIYQARQVFEMAR-SMGTHSFRLLDI

GGGFVSDG--GHGVSFSAAADSINDALDRYFP--PCMG--ITVIAEPGRFFAEEIFTLAS

QVFGSRVRSRN--GHE---------VVEYWINDGIYGSMNCLLYDHATLSVRALQLHS--

-----RDTIFEE-------GMSDS---------------------TIFGPTCDGLDTVMQ

NVQLP-HMQCGDWLIFPRMGAYTKAAASSFNGFDVSGAT---------------------

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83

-----------------------------------

>Anemia_tomentosa

------------------------------------------------------------

------------------------------------------------------------

------DDLIRMKILNSK---------SEDAFYVMDIGAVLRLWKTWKLHLPRVHPFYAV

KCNSDGVLLALLSALGAGFDVASKAELDMVSYLG-VGNDRVIFANPCKLPSHIGYAASHN

IHLTTFDSEVELYKLQKMNPKAEVVLRIRVCDPGA-------RCPLGVKYGAE--MEECR

SLLMVARNVGLEVAGVAFHVGSGASD--PSSFAKGITQAREVFDMAT-SMGITSLRLLDI

GGGFVSDG--GHGVNFAAAAASVNDALETFFP--PSMG--VTVIAEPGRFFAEESFTLAA

QIFGSRVRMID--EKK---------KVEYWINDGIYGSMNCLLYDHAIISVRALPVSS-A

-----DNVMPNN-------EERQS---------------------TIFGPTCDGLDTLMQ

NVWLP-QMQCGDWLVFPRMGAYTKAAASSFNGFDISNA----------------------

-----------------------------------

>Cheilanthes_arizonica

------------------------------------------------------------

------------------------------------------------------------

-----LDNLIKKQIVSSK---------GEDAFYVMDVGVILRLWRTWKLLMPRVHPFYAV

KCNSDVPLLALLSTLGSGFDVASKAELDLVRSLG-IGGDRIIFANPCKLPSHITHAANHD

VHLTTFDSEGELYKLHKMNPQAEVVLRIRVCDAGA-------RCPLGVKYGAE--MEDCE

NLLYVAKNLGLKVVGIAFHVGSGASD--PSSFAQGIGQARLLFDMAK-AMGIASLRLLDI

GGGFVSDG--GMGVSFSAAAASINEALEKFFP--SSLG--VTVIAEPGRFFAEESFTLAA

QVFGSRMRQRN--GEK---------VAEYWINDGIYGSMNCLLYDHATLSVRALPICS-G

-----KDLNASS-------DGCQS---------------------TIFGPTCDGLDTVMQ

NVWLP-QMECGDWLVFPRMGAYTKAAASSFNGFDI-------------------------

-----------------------------------

>Thyrsopteris_elegans

------------------------------------------------------------

------------------------------------------------------------

-----MDDMILKRIRRTG---------TEDAFYVMDIGVLLRLWKTWKLAMPRVHPFYAV

KCNGDGMLLALLAALGAGFDVASKAELDTVQNLG-VGGDRIFFSNPCKLPSHVTYAAARD

VHLTTFDSEAELYKIWKLNPQAEVVLRIHICDVGA-------RCPLGVKYGAE--SEECE

GLLSLAKYLGLQVVGVAFHVEGGASD--PMSFANGIAHARKVFDLAR-FLRITSLRLLDI

GGGFVSDG--GHGVSFSAVAAAINSALEKYFP--PSSG--VTVIAETGRFFAEGAFTLAA

QVFGSCVRTRN--GEK---------VAEYWINDGIYGSMICLLYDHAIISVRALLVCSGR

-----DG-IASY-------EGFES---------------------TIFGPTCDGLDTLMQ

NVWLP-HLQVGDWLVFPCMGAYTKAAASSFNGFDIGNMSTAYV-----------------

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84

-----------------------------------

>Deparia_lobato-crenata

------------------------------------------------------------

------------------------------------------------------------

-----IDEVIKKQILSSR---------TEDAFYVMDIGVLLRLWKKWRFSMPRVHPFYAV

KCNSDRMLLAILVALGAGFDVASKLELDIVRDLG-VGGDRIIFANPCKLPSHIQHARNHD

VHLTTFDSETELHKLHKMNPRAEAVLRIRVCDAGA-------RCPLGVKYGAE--MNECE

SLLLVAKGLGLTVVGVAFHVGSGASD--PSSFAQGIAQARQVFDMAK-AMGMHSLRLLDI

GGGFVSDG--GYGVSFSAAAASINDALDRYFP--SCMG--ITVIAEPGRFFAEETFTLAS

QVFGIRVRSRN--GHD---------VVEYWINDGIYGSMNCLLYDHATLSVRALQMCS--

-----KDTVFGE-------EMSES---------------------TIFGPTCDGLDTVMQ

NVWLP-RMQCGDWLVFPRMGAYTKAAASSFNGFDVSGAT---------------------

-----------------------------------

>Pteris_ensigormis

------------------------------------------------------------

------------------------------------------------------------

-----LDNLIKKQIITTK---------AEDAFYIMDVGVLLRLWRLWKLLMPRVHPFYAV

KCNSDVLLLALLSSLGAGFDVASKAELDLVRSLG-VGGDRIIFANPCKLPSHVLHAANYD

VHLTTFDSEGELYKLHKLNPQAEVVLRMRVCDPGA-------RCPLGVKFGAD--MEDCE

SLLHVAKNLGLKVVGIAFHVGSGASD--PSSFAHGIAQARLLFDTAK-KIGLTCLRLLDI

GGGFVSDG--GVGVSFPAAASSINEALEKFFP--PSSG--VTVIAEPGRFFAEESFTLAA

QVFGSRVRQRD--GSK---------VVEYWINDGIYGSMNCVFYDHAVLSVRWLQISS-A

-----KDT-PES-------DGCQS---------------------TIFGPTCDGIDTVMQ

NVWLP-HMDCGDWLVFPRMGAYTKAAASSFNGFDI-------------------------

-----------------------------------

>Myriopteris_eatonii

------------------------------------------------------------

------------------------------------------------------------

-----LDNLIEKQIVSSK---------AEDAFYVMDVGVVLRLWRTWRLSMPRVHPFYAV

KCNSDVPLLALLSTLGAGFDVASKAELDLVNSLG-VGGDRIIFANPCKLPSHIVHAANHG

VHLTTFDSEGELYKLHKLNPQAEVVLRIRVCDAGA-------RCPLGVKYGAE--MEDCE

NLLYVAKNLGLKVIGVAFHVGSGASD--PSSFAHGISQARLLFDMAK-AMGITSLRLLDI

GGGFVSDG--GMGVSFSAAAASINEALEKFFP--SSLG--VTVIAEPGRFFAEESFILAA

QVFGSRVRQRD--GAK---------VAEYWINDGIYGSMNCLLYDHATLSVRALPICS-G

-----KNFNAGN-------DGCSS---------------------TIFGPTCDGLDTVMQ

SVWLP-QMECGDWLVFPRMGAYTKAAASSFNGFDI-------------------------

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85

-----------------------------------

>Gymnocarpium_dryopteris

------------------------------------------------------------

------------------------------------------------------------

-----IDEVIKKQILSTR---------TEDAFYVMDIGVLLRLWKKWIFSMPRVHPFYAV

KCNSDRVLLAILAALGAGFDVASKAELDILRNLG-VGGDRIIFANPCKLPSHIQHARNHN

VHLTTFDSETELYKLHKMNPKAEAVLRIRVCDAGA-------RCPLGVKYGAE--MNELE

SLLLVANGLGLTVVGVAFHVGSGASD--PSSFAQGIAQARQVFDMAK-AMGMHSLRLLDI

GGGFVSDG--GHGVSFSAAAASINDALDRYFP--SCMG--ITVIAEPGRFFAEETFTLAS

QVFGSRARSRN--GHD---------VVEYWINDGIYGSMNCLLYDHATLTVRALQICS--

-----RDTVFGE-------EMSES---------------------TIFGPTCDGLDTVLQ

NVWLP-RLQCGDWLVFPRMGAYTKAAASSFNGFDVSGAT---------------------

-----------------------------------

>Asplenium_platyneuron

------------------------------------------------------------

------------------------------------------------------------

-----IDEVIKQQILSAR---------PEDAFYVMDIGVLLRLWNKWRVSVPRVHPFYAV

KCNSDRVLLAVLAALGAGFDVASKLELDMVKDLG-VGGDRIIFANPCKLPSHIQHARNHG

VHLTTFDSETELYKLHKLNPEAEAVLRIRVSDPGA-------RCPLGVKYGAE--LSECE

NLLLVAKGLGLTVVGVAFHVGSGASD--PSSFAEGITQARQVFDIGK-AMGIHSFRLLDI

GGGFVSDG--GHGVSFSAAAAAINNALDRYFP--SCMG--ITVIAEPGRFFAEETFTLAS

QVFGCRVRSRN--GHD---------VVEYWINDGIYGSMNCLLYDHATLSVRALQICS--

-----RDTACGE-------ELSES---------------------TVFGPTCDGLDTVMQ

NVWLP-RMQCGDWLVFPRMGAYTKAAASSFNGFNISGA----------------------

-----------------------------------

>Cystopteris_fragilis

------------------------------------------------------------

------------------------------------------------------------

-----IDEVIKKQILKTL---------PEDAFYVMDIGVLLRLWKKWMFSMPRVHPFYAV

KCNSDHVLLAILAALGAGFDVASKVELDMVRDLG-VGGDRIIFANPCKLPSHIQHARNHD

VHLTTFDSETELYKLLKMNPKAEAVLRIRVCDAGA-------RCPLGVKYGAE--MSECE

SLLLVAKSLGITVVGVAFHVGSGASD--PSSFAQGIAQARQVFDMAK-AMGTHSFRLLDI

GGGFVSDG--GQGVSFSAAAASINDALDRYFP--SCMG--ITVIAEPGRFFAEETFTLAS

QVFGSRARSRN--GHE---------VVEYWINDGIYGSMNCLLYDHATLTVRALQICS--

-----GDTVFGE-------EMYKS------------------------------------

------------------------------------------------------------

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86

-----------------------------------

>Dipteris_conjugata

------------------------------------------------------------

------------------------------------------------------------

-----MDDLICKNIMNTG---------AEDAFYVMDVGFLLRLWKTWKGAMPRVHPFYAV

KCNADGVLLALLAALGAGFDVASKAELDMVRCLG-VGGDRIIFANPCKLPSHIANAASSG

VHLTTFDSEVELYKLRNVNPQAEVVLRIRVCDPGA-------RCPLGVKYGAE--MEECE

SLLMVAKNLGVQVVGVAFHVGSGASD--PSSFAEGIAQSRKVFDMAS-KIGISSLRLLDI

GGGFVSDG--GHGVSFSAAAAAINDALEKFFP--PYCG--VTVIAEPGRFFAEGSFTLAA

QVFGSRMRMTN--GQE---------VAEYWINDGIYGSMNCLLYDHAIISVRPLPICSGK

-----DG-ISQV-------KGCQS---------------------TVFGPTCDGLDTLMQ

NVWLP-YLQCGDWLVFPRMGAYTKAAASSFNGFDISNITTVYVC----------------

-----------------------------------

>Dennstaedtia

------------------------------------------------------------

------------------------------------------------------------

-----IDEVIKKQILSTR---------TEDAFYVMDVGVLLRLWKKWKMLMPRVHPFYAV

KCNSDHVLLALLAALGAGFDVASKVELDMVRDLG-VGGDRIIFANPCKLPSHIQHACNHD

IHLTTFDSETELYKLCKINPKAEAVLRIRVCDAGA-------RCPLGVKYGAE--MDECE

SLLLVAKGLGLAVVGVAFHVGSGASD--PSSFAQGITQARQVFDMAK-GMGIQSFRLLDI

GGGFVSDG--GYGVSFSAAAASINNALEKFFP--SCMG--ITVIAEPGRFFAEETFTLAS

QVFGRRVRSRN--GHD---------VAEYWINDGIYGSMNCLLYDHATLSVRALQVCS--

-----MDT---E-------ETSES---------------------TIFGPTCDGLDTVMQ

SVQLP-RLQCGDWLVFPRMGAYTKAAASSFNGFDV-------------------------

-----------------------------------

>Lindsaea_linearis

------------------------------------------------------------

------------------------------------------------------------

-----LDDLIYKQIVSTK---------AEDAFYVMDVGKVLRLWSTWKLLMPRVHPFYAV

KCNSDLPLLALLSALGAGFDVASKAELDMVRSIG-VRGDRIIFANPCKLPSHISYSAKYD

VHLTTFDSEAELYKLHKVNPKAEVVLRIRVCDSGA-------RCPLGFKYGAE--MEECE

GLLNVANTLGLDVVGIAFHVGSGASD--PLSFAQGIAQARQLFDMAK-AMGMTSLRLLDI

GGGFVSDD--GHGVSFSAAASSINDALEKYFS--PSLG--ITVIAEPGRFFAEEPFTLVT

QVFGSRLRKRN--GGQ---------IAEYWINDGLYGSMNCLVYDHAALSVRGLQVCS-K

-----EEHILED-------NGCES---------------------TIFGPTCDGLDTVMQ

NVWLP-RMQCGDWLVFPRMGAYTKAAASSFNGFDI-------------------------

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87

-----------------------------------

>Davallia_fejeensis

------------------------------------------------------------

------------------------------------------------------------

-----LDDFVRKQIVNTQ---------TEDAFYVMDVGVLLCLWQTWKLSMPRVHPFYAV

KCNSDVLLLSLLSTLGAGFDIASKAELDIVRGLG-VGGDRIIFANPCKMPSHILHAANYD

VHLTTFDSEGELYKLHRLNPQAEVLLRIRVCDAAA-------RCPLGVKYGAE--MEDCE

SLLGVAKNLGLNVVGIAFHVGSGASN--PSSFAHGIAQARVLFDIAK-SLGITTFRLLDI

GGGFVSDG--GLGVSFSVAAASINDALDKYFP--PSLG--LTVIAEPGRYFAEESFTLAA

QVFGSRVRIRN--GLK---------VAEYWINDGIYGSMNCLLYDHATLSVRALQISS-E

-----KDFITGD-------DGCDS---------------------TIFGPTCDGLDTIMQ

NVRLP-HLQCGDWLVFPRMGAYTKAAASTFNGF---------------------------

-----------------------------------

>Lygodium_japonicum

------------------------------------------------------------

------------------------------------------------------------

------DDVIENRIINIG---------AEDAFYVMDIGQLLRLWKTWKLALPRVHPFYAV

KCNADRVLLALLAALGAGFDVASKAELEIVQSLG-VGGDRLIFANPCKLPSHISYAGGRG

IHLTTFDSEAELYKLRKFNPQAEVVLRIRVCDSGA-------RCPLGVKYGAE--MEECE

SLLLTAKILGLQVVGVAFHVGSGASD--PLSFANGIAQARKVFDMAM-LLGLTSLRLLDI

GGGFVSDG--GHGVSFSSAAEAINEALDKFFP--PSMC--VTVLAEPGRFFAEDSFTLAA

QIFGSRMRFRN--GQQ---------VAEYWINDGIYGSMNCLLYDHAVISVRPLPVSSRK

-----DSLLAQH-------AGCHS---------------------TIFGPTCDGLDTLME

NVWLP-YLECGDWLVFPRMGAYTKAAASSFNGFDISNIETIYV-----------------

-----------------------------------

>Pteris_vittata

------------------------------------------------------------

------------------------------------------------------------

-----LDNLIKKQILTTR---------AEDAFYIMDVGVVLRLWRTWKLSMPRVHPFYAV

KCNSDVPLLALLSVLGAGFDVASKAELDLVRSLG-VGGDRIIFANPCKLPSHVVHAANHD

VHLTTFDSEGELYKLHRFNPQAEVVLRIRVCDPGA-------RCPLGVKYGAE--MADSE

SLLYLAKSLGLKVVGIAFHVGSGASD--PSSFAHGIAQARLLFDTAK-TMGLTSLRLLDI

GGGFVSDG--GLGVSFSAAAASINEALEKFFP--PSFG--VTVIAEPGRFFAEESFTLAA

QVFGSRVRQRD--GLK---------LAEYWINDGIYGSMNCLLYDHAVLSVRGLQMSTVV

-----KDSGPES-------DGCQS---------------------TIFGPTCDGLDTVMQ

NVWLP-HMDCGDWLVFPRMGAYTKAAASSFNGFDI-------------------------

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-----------------------------------

>Hymenophyllum_bivalve

------------------------------------------------------------

------------------------------------------------------------

-----MDELIKKKVVNTA---------AEDAFYVMDIGVLLRLWKTWKLALPRVHPFYAV

KCNADKVLLALLAALGAGFDVASKTELDTVMKLG-VGGDRIIFANPCKLPSHITYAAGLG

VHLTTFDSEVELYKVRKVNPQAEVVLRIRICDAGA-------RCPLGAKYGAE--FDECE

SLLLVARNLGLQVVGVAFHVGSGASD--PSSFAEGIAQARKVFDMAI-KMGMTSLRLLDI

GGGFVSDG--GQGVGFFAAASSINDALEKFFP--HCSG--VTVIAEPGRFFAEGSFTLAA

QVFGNRMRMRN--GQE---------VAEYWINDGIYGSMNCLLYDHAVISVRALPVSRRK

-----DG-VNKH-------EGCLS---------------------TIFGPTCDGLDTLMQ

DVWLP-YMQCGDWLVFPRMGAYTKAAASSFNGFDIRESTTVYVC----------------

-----------------------------------

>Didymochlaena_truncatula

------------------------------------------------------------

------------------------------------------------------------

-----LDNFLKKQIVNTQ---------IEDAFYVMDVGVVLRLWQIWKLAMPRVHPFYAV

KCNSDVPFLALLSSLGAGFDVASKAELDIVRGLG-VGADRIIFANPCKLPAHILHATNHD

VHLTTFDSEGELYKIYKGNPQAEVVLRIRVCDPGP-------RCPLGVKYGAE--MEDCE

SLFGVAKNLGLKVVGIAFHVGSGASD--PLSFAHGIAQARLLFDMAK-SLGITTFRLLDI

GGGFVSDG--GLGVSFSAAAASINEALDEYFP--PSLG--ITVIAEPGRYFAEESFTLAT

QVFGSRVHKRN--GLK---------VAEYWINDGVYGSMNCLLYDHATLSVRALQVGC-V

-----KDFMIGD-------DGCES---------------------TIFGPTCDGLDTVMQ

NVWLP-RLQCGDWLVFPRMGAYTKAAASSFNGFDI-------------------------

-----------------------------------

>Cystopteris_reevesiana

------------------------------------------------------------

------------------------------------------------------------

-----IDEVIKKQILKTL---------PEDAFYVMDIGVLLRLWKKWMFSMPRVHPFYAV

KCNSDHVLLAILAALGAGFDVASKVELDMVRDLG-VGGDRVIFANPCKLPSHIQHARNHD

VHLTTFDSETELYKLLKMNPKAEAVLRIRVCDAGA-------RCPLGVKYGAE--MSECE

SLLLVAKSLGLSVVGVAFHVGSGASD--PSSFAQGIAQARQVFDMAK-AMGTHSFRLLDI

GGGFVSDG--GQGVSFSAAAASINDALDRYFP--ACMG--ITVIAEPGRFFAEETFTLAS

QVFGSRARSRN--GHE---------VVEYWINDGIYGSMNCLLYDHATLTVRALQICS--

-----GDTVFGE-------EMCKS---------------------TIFGPTCDGLDTVMQ

NVWLP-RLQCGDWLVFPRMGAYTKAAASSFNGFDVSGAT---------------------

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-----------------------------------

>Vittaria_lineata

------------------------------------------------------------

------------------------------------------------------------

-----LDNLLKKHVVISK---------EEDAFYSMDVGIVLRLWRTWKLAMPRVHPFYAV

KCNSDASLLALLSALGAGFDVASKAELDVVRSLG-IGGDRIIFANPCKLPSHILHAADHN

VLLTTFDSEGELYKLKKLNPQAEVVLRIRVCDAGA-------RCPLGVKYGAE--MEDCE

KLLFLAKSLRLKVVGIAFHVGSGASD--PSSFAQGMAQARILFDKSK-AIGLTSLRLLDI

GGGFVSDG--GMGVSFSAAAVSINDALDKFFP--PSLG--VTVIAEPGRFFAEESFTLAA

QVFGRRVCQRD--GSE---------IAEYWINDGIYGSMNCLLYDHAILSVRPLLICS-A

-----RDLNPSS-------DGCKS---------------------TIFGPTCDGLDTVLK

NIWLP-YLDCGDWLVFPRMGAYTKAAASCFNGFDI-------------------------

-----------------------------------

>Plagiogyria_japonica

------------------------------------------------------------

------------------------------------------------------------

-----IDEMIKKQIVNTR---------TEDAFYVMDIGVVLRLWKTWKLSMPRVHPFYAV

KCNSDRVLLALLSALGAGFDVASKAELDMVRDLG-VGGDRIIFANPCKLPSHILHAANHD

VHLTTFDSEAELYKLLKVNPQAEVVLRIRVCDEGA-------RCPLGVKYGAE--MEECE

SLLLIAKGLGLKVVGVSFHVGSGASD--PSSFAQGISQARKVFDMAK-VMEMTSLRLLDI

GGGFVSDG--GHGVCFSAAAASINDALETFFP--SCMG--VTVIAEPGRFFAEESFTLAA

QVFGSRVRRRN--GQE---------VAEYWINDGIYGSMNCLLYDHAILSVRALRACSM-

-----KDSMVGD-------EGTES---------------------TIFGPTCDGLDTIMQ

NVWLP-RMQCGDWLVFPRMGAYTKAAASNFNGFDISGITTVCVC----------------

-----------------------------------

>Notholaena_montieliae

------------------------------------------------------------

------------------------------------------------------------

-----FDNLLKKQIVSSK---------AEDAFYVMDVGAVLRLWRTWKLSMPRVHPFYAV

KCNSDVPLLALLSTLGAGFDVASKAELDLVRSLG-IGGDRIIFANPCKLPSHIMHAANHD

VHLTTFDSEGELYKLQKLNPQAEVVLRIRVCDAGA-------RCPLGVKYGAE--MEDCE

NLLYIAKNLGLKVVGIAFHVGSGASD--PSSFAHGICQARLLFDMAK-VMGIASLRLLDI

GGGFVSDG--GMGVSFSAAAASINEALEKFFP--PGLG--VTVIAEPGRFFAEESFTLVA

QVFGSRVRQRD--GGK---------VAEYWINDGIYGSMNSLLYDHATLSVRALPIYS-G

-----KDSNASI-------DGCQS---------------------TIFGPTCDGLDTVMQ

NVWLP-QMECGDWLVFPRMGAYTKAAASSFNGFDI-------------------------

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-----------------------------------

>Woodsia_scopulina

------------------------------------------------------------

------------------------------------------------------------

-----LDCLIKKQIVSTQ---------TEDAFYVMDVGVVLRLWQTWKLSMPRVHPFYAV

KCNSDVPLLALLSALGAGFDVASKAELDIVRGLG-VGGDRMIFANPCKLPSHILHAANHD

VHLTTFDSEGELHKLYKVNPQAEVVLRIRVCDAGA-------RCPLGVKYGAE--MEDCE

SLLGVAKTLGLKVAGIAFHVGSGASD--PSSFAHGIAQARALFDMAR-SMGITTFRLLDI

GGGFVSDG--GLGVSFSAAAASINEALDKYFP--PSLG--ITVIAEPGRYFAEESFTLAA

QVFGSRVRKRN--GQK---------VAEYWINDGIYGSMNCLLYDHATLSVRALQFGS-V

-----IDFMPGD-------DGCES---------------------TIFGPTCDGLDTIMQ

NVWLP-HLQCGDWLVFPRMGAYTKAAASSFNGFDISGIT---------------------

-----------------------------------

>Polypodium_amorphum

------------------------------------------------------------

------------------------------------------------------------

-----LDDFLRKQIVNTK---------AEDAFYVMDVGVVLRLWQTWKLSMPRVHPFYAV

KCNSDVLLLAILSSLGAGFDIASKAELDIVRGLG-VGGDRIIYANPCKLPSHILHAANYD

VHLTTFDSEGELYKLYKLNPQAEVVLRIRVCDAGA-------RCPLGVKYGAE--MEDCE

SLLGVAKNLGLKVVGVAFHVGSGASD--PSSFAHGIAQARVLFDMAK-SVGITTFRLLDI

GGGFVSDG--GLGVSFSAAAASINEALDKYFP--SSLG--ITVIAEPGRFFAEESFTLAA

QVFGSRVRKRN--GQK---------VAEYWINDGIYGSMNCLLYDHATLSVRAVQVSS-V

-----KDLMLG--------DGCDS---------------------TIFGPTCDGLDTVMQ

NVWLP-HLECGDWLVFPRMGAYTKAAASTFNGFDIGD-----------------------

-----------------------------------

>Sphaerocarpos_texanus

------------------------------------------------------------

------------------------------------------------------------

------DTFIRKKVAGTG---------MESAFYVMDLGAVVRQWKLWVASMPRVKPFYAV

KCNPDVALLALLHKLGAGFDVASKAELMAVTEIG-AVPDNIIFANPCKLPTHIVEAGKFG

VLRTTFDSESELFKLKKHLPHAEVVLRIRADDPTA-------RCPLGIKYGAE--MEECE

QLLKVAKQLDLKVVGVAFHVGSGASD--ASAFAYGIECAKQVFETAA-ALGLNDMKLLDI

GGGFVSSS--SSGVMFSTAAVAINKALEKFFP--VSMG--VTIIAEPGRYFAEDAFTLAT

YVFGSRMRNKG--SGK---------LAEYWVNDGIYGSMNCLLYDHATLSVRALSQNEGG

-----EAEWGATG-----ENVYQS---------------------TIFGPTCDGLDTLMR

DVWLP-QLQCGDWLLFPRMGAYTKAAGSNFNGFNVKDIPTFYVYSCG-------------

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91

-----------------------------------

>Marchantia_paleacea-non_mycorrizal

------------------------------------------------------------

------------------------------------------------------------

------DAFIRKKVNDSE---------LESAFYVMDLGSVLRQWKLWVTALPRVKPFYAV

KCNPDAALLALLHKLGAGFDVASKSELKAVTDLG-AVPENIIFANPCKLPTHITEAGKYG

VLRTTFDSESELYKLKKFLPHAEVILRIRADDPTA-------RCQLGTKYGAE--LEECE

QLLIVAKQLSLKVVGVAFHVGSGASD--ASAFAYGIECAKHVFDVAE-AMGLNGMKILDI

GGGFVSNA--SAGVNFATAATTINKALDKCFP--VSMG--VTVVAEPGRYFAEDAFTLAT

YVFGCRMRKKG--GTK---------QAEYWVNDGIYGSMNCLLYDHAVLSVRALSQDDDA

-----DAEWRDR-------NVYQS---------------------TIFGPTCDGLDTVMR

DIYLP-ELQCGDWLLWPRMGAYTKAAGSNFNGFSVKDIPTSYVY----------------

-----------------------------------

>Marchantia_polymorpha

------------------------------------------------------------

------------------------------------------------------------

------DSFIRKKVNDSE---------LESAFYVMDLGSVLRQWKLWVTALPRVKPFYAV

KCNPDAALLALLHKLGAGFDVASKSELKAVTDIG-AVPENIIFANPCKLPTHITEAGKHG

VLRTTFDSESELYKLKKFLPHAEVVLRIRADDPTA-------RCQLGTKYGAE--LEECE

QLLTVAKQLSLKVVGVAFHVGSGASD--ASAFAYGIECAKYVFGVAE-AMGLNDMKILDI

GGGFVSNA--SAGVNFATAASTINKALDKCFP--VSMG--VTVIAEPGRFFAEDAFTLAT

YVFGCRMRKKG--GTK---------QAEYWVNDGIYGSMNCLLYDHAVLSVRALSQDDDA

-----EEEWRDR-------NVYQS---------------------TIFGPTCDGLDTVMR

DIYLP-ELQCGDWLLWPRMGAYTKAAGSNFNGFNVKDIPTSYVY----------------

-----------------------------------

>Pellia_cf._Epiphylla

------------------------------------------------------------

------------------------------------------------------------

-----LDAYIQSKIFETG---------LEDAFYVMDLGSVVRNWELWKSSMPRVKPFYAV

KCNSDLALLSLLAKLGAGFDVASKAELGAVAGLQ-VSPDRMIFANPCKLPTHIVDAGNHG

VYRTTFDSESELYKLKKYLPQAEVVLRIRADDPSA-------RCPLGVKYGAE--FDECE

HLLRVAKQLHLKVVGVAFHVGSGASD--ASAFEYGILSARRMFDVAA-SLGLGQLNLLDI

GGGFVSTS--GVGVNFSLAATTINDALNKHFP--EGMG--VDIIAEPGRYFAEEAFTLVT

NVFGTRMRNKS--GVK---------TAEYWVNDGIYGSMNCLLYDHATLNVRALPQASND

-----EAKWVDK-------TVHQT---------------------TIFGPTCDGLDTLMK

DIWLP-ELQCGDRLVFMRMGAYTKSAGSSFNGFDVNDITTAYVYSAA-------------

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92

-----------------------------------

>Riccia_berychiana

------------------------------------------------------------

------------------------------------------------------------

------DAFIRKTALDTC---------MESAFYVMDLGSVLKQWKMWVACLPRVKPFYAV

KCNPDVALLATLHKLGAGFDVASKAELKAVSDIG-AAPENMIFANPCKLPTHVVEAGKYG

VLRTTFDSESELHKLKKYLPNAEVILRIKADDPNA-------RCPLGTKYGAE--LDECE

QLLAVVKQLSLKVVGVAFHVGSGASD--PCAFAHGIACARHVFDLAA-AMGLNDMKIVDI

GGGFVSNA--SSGVNFAAAAAAINKALDKHFP--VSTG--VSVIAEPGRFFAEDAFTLAT

YVFGSRMRKKD--GIK---------QAEYWVNDGIYGSMNCLLYDHAVLSVRALSQDRDA

-----EAEWHDK-------NVYPS---------------------TIFGPTCDGLDTLMR

DIYLP-QLQCGDWLVFPRMGAYTKSAGSTFNGFDVKDIPTLYVY----------------

-----------------------------------

>Pallavicinia_lyellii

------------------------------------------------------------

------------------------------------------------------------

-----IDQFIEQKIAATH---------AEDAFYVMDLGLVLRLWRAWENALPRVKPFYAV

KCNTDATLLSLLAKAGAGFDVASKAELAVVRQVG-VVPDRIIFANPCKLPSHIVDAAKHG

VRRTTFDSETELCKLSKYHPKAELVLRIRADDVVA-------RWPLGVKYGAE--LDECE

NLLGGAKKLGLLVVGVAFHVGSGATH--AASFAQGIAFARGVFDLAS-ALGLPPLKLLDI

GGGFVSKG--GVGVRFSSAAAVINKALDEHFP--ESMG--VEVIAEPGRYFAEEAFTLAT

HVFGSRIRYKG--ETK---------TADYWVNDGIYGSMNCLLYDHATLSVRAVSSAAAD

DKPADENQWVEQ------QEVYQS---------------------TVFGPTCDGLDTILR

DIWLP-ELHCGDWLVFPRMGAYTKSAGSNFNGFDLGEIGTFYVY----------------

-----------------------------------

>Huperzia_myrisinites

------------------------------------------------------------

---------------------------------------------------------ITS

SSQEDVDAFIESTIRSNN---------LQDAFYVLDLAVVVQLFNDWIAALPKVKPYYAV

KCNPSPPLLSTLAALGAGFDCASKSELEQIISMG-VSAQRIIFANPCKMLSHIKYASAVG

ANLTTYDSENEVAKVKLHSPNAKLLLRLRADDRSS-------KWPLGVKYGA--LASEVE

HLLMVAANAGVDVVGVSFHIGSGASD--GRAYLDAISAARGVFDKAL-SMGLPAMKILDI

GGGFTVGN--NGELKLAEAAKVINAALHEYFPEEMG----VSVIAEPGRYFAEAPTTLAA

MIYGKRTRGEV---------------REYWINDGIYGTMNCLIHDYAVLSPRPLACVSQ-

----RNNLS-----C-AKLPLHTS---------------------TVFGPTCDSLDTILK

DHPLP-DLVDGDWIVFPNMGAYTHCAGSSFNGFDISAIRT--------------------

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93

-----------------------------------

>Lycopodiella_apressa

------------------------------------------------------------

------------------------------------------------------------

--------FIETIIRSKS---------MQDAFYVLDIAAIVQLFCDWVAALPRVKPFYAV

KCNPSIPLVSTLAALGAGFDCASKSELELVSSIG-VSSQRIIYANPCKMTSHIAYASSIG

VNLTTYDCENEVGKVKRNNPNAQLLLRLRADDLSS-------KWPLGVKYGA--LISEVE

QLLTAAASAKMHVVGVSFHIGSGASD--ARSYLEAIAAARKVFDMAL-TLGLPAMHILDI

GGGFTVGN--NGELKLAEAAIVINAALDQYFPEEMG----VTIIAEPGRYFAEVPTTLAA

MVYGKRVRSEV---------------REYWINDGIYGTMNCLIHDYAVLCPRPLACVSS-

----RNNTS-----C-NGLPKFKS---------------------TVFGPTCDSLDTVLK

EHPLP-DLVDGDWIVFPNMGAYTHCAGSSFNGYDTSAIPT--------------------

-----------------------------------

>Phylloglossum_drummondii

------------------------------------------------------------

---------------------------------------------------------ITS

NSQKDVDGFIDTTIRSKN---------LRDAFYVLDLAVVVQLFNDWVAALPKVKPYYAV

KCNPSPPLVSTLAALGAGFDCASKSELEQIISMG-VSAQRIVFANPCKMVSHIKYASSVG

VSLTTYDSEHEVAKIKLHSPNAKLLLRLRADDRSS-------KWPLGVKYGA--LPSEVD

HLLEVAASAKVEVVGVSFHIGSGASD--GRAYLDAIAAARGVFDKAL-SMGLPGMRILDI

GGGFSVGN--NGELKLAEAAEAINRALDQYFPEELG----VKVIAEPGRYFAETPTTLAA

MVYGKRVREGV---------------REYWINDGIYGTMNCLIHDYAVLCPRPLASASH-

----TTNLS-----C-ANLPLHIS---------------------TVFGPTCDSLDTILQ

EHPLP-DLADGDWIVFPNMGAYTHSAGSSFNGFDTAAIPTY-------------------

-----------------------------------

>Huperzia_selago

------------------------------------------------------------

------------------------------------------------------------

-------------------------------FYVLDLAVVVQLFNDWVAALPKVKPYYAV

KCNPSPPLLSTLAALGAGFDCASKSEVEQIISMG-VSAQRIIFANPCKMLSHIKYASSVG

VNLTTYDSEHEVAKVKLHSPNAKLLLRLRADDRSS-------KWPLGVKYGA--LSSEVE

HLLMVAANAKVDVVGVSFHIGSGASD--GRAYLDAIAAARGVFDKAL-SMGLPAMHILDI

GGGFTVGN--NGELKLAEAAKVINAALHEYFPDELG----VSVIAEPGRYFAEAPTTLAA

MIYGKRMREEV---------------REYWINDGIYGTMNCLIHDYAILCPRPLACVSQ-

----GNNLS-----C-AKLPLHTS---------------------TVFGPTCDSLDTILK

DHPLP-DLVDGDWIVFPNMGAYTHCAGSSFNGFDTSAIRTY-------------------

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94

-----------------------------------

>Huperzia_selago-2_samples_combined

------------------------------------------------------------

------------------------------------------------------------

-------------------------------FYVLDLAVVVQLFNDWVAALPKVKPYYAV

KCNPSPPLLSTLAALGAGFDCASKSEVEQIISMG-VSAQRIIFANPCKMLSHIKYASSVG

VNLTTYDSEHEVAKVKLHSPNAKLLLRLRADDRSS-------KWPLGVKYGA--LSSEVE

HLLMVAANAKVDVVGVSFHIGSGASD--GRAYLDAIAAARGVFDKAL-SMGLPAMHILDI

GGGFTVGN--NGELKLAEAAKVINAALHEYFPDELG----VSVIAEPGRYFAEAPTTLAA

MIYGKRMREEV---------------REYWINDGIYGTMNCLIHDYAILCPRPLACVSQ-

----GNNLS-----C-AKLPLHTS---------------------TVFGPTCDSLDTILK

DHPLP-DLVDGDWIVFPNMGAYTHCAGSSFNGFDTSAIRTY-------------------

-----------------------------------

>Lycopodium_deuterodensum

------------------------------------------------------------

------------------------------------------------------------

----------------------------QDAFYVLNIAAVVQLFYDWVAALPRVRPYYAV

KCNPSPPLLSTMAALGAGFDCASKSELEQVIALG-VSPRRIVFANPCKMPSHIKHASSVG

VNLTTYDCEHEVTKVKLNNPNAKLLLRLRADDPSS-------KWPLGVKYGA--LTHEVE

DLLMAASKAQVDVVGVSFHIGSGASD--ARSYLYAIAAARKVFEKAL-ALGLPAMNVLDI

GGGFTVGN--NGELKLAEAAKAINAALDQYFPEELG----VSIIAEPGRYFAEVPTTLAS

MVYGKRVRDEL---------------REYWINDGIYGTMNCLIHDYAVLCPRPLAFVSQ-

----RNNTS-----C-VGLPVYKS---------------------TVFGPTCDSLDTVLK

DHPLP-DLVDGDWIVFPNMGAYTHCAGSSFNGYDTSAIQT--------------------

-----------------------------------

>Huperzia_squarrosa

------------------------------------------------------------

------------------------------------------------------------

----------------------------QDAFYVLDLAVVVQLFNDWVAALPMVKPYYAV

KCNPSPPLLSTLAALGAGFDCESKSEVELIISMG-VSEQRIIFANPCKMPSHIKYASSVG

VNLTTYDSEHEVAKVKLHSPNAKLLLRLRADDRSS-------KWPLGVKYGA--LSSEVD

HLMMVAAKAKLDVVGVSFHIGSGASD--GRAYADAIAAARAVFDKAL-SMGLPPMHILDI

GGGFTVGN--NGELKLAEAAKVINAALHEYFPEEMG----VSVIAEPGRYFAEAPTTLAA

MIYGKRTRGEV---------------REYWINDGIYGTMTCLIHDYAVLAPRPLACVSQ-

----RNNLS-----C-AKLPLHTS---------------------TVFGPTCDSLDTILK

DHPLP-DLVDGDWIVFPNMGAYTHCAGSSFNGFDISAIRT--------------------

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95

-----------------------------------

>Pseudolycopodiella_caroliniana

------------------------------------------------------------

------------------------------------------------------------

--------FIESIIRSKG---------MQDAFYVLDLAAIVHLFCEWVAVLPRVQPFYAV

KCNPSLPFLSTMAALGAGFDCASKSELELVLSIG-VSSQRIIYANPCKMMSHIAYASSVG

VNLTTYDSENEVIKVKRNNPNAKLLLRLRADDLSS-------KWPLGVKYGA--LMSEVE

QLLTAAADENMHVVGVSFHIGSGASD--ARSYLEAIAAARKVFDIAL-TLGLPALQILDI

GGGFTVGN--NGELKLAEAAIVINAALDQYFPEEMG----VTIIAEPGRYFAEVPTTLAA

MVYGKRVRGEV---------------REYWINDGIYGTMNCLIHDYAVLCPRPLAFVSN-

----ARNVS-----C-TGLPRFKS---------------------TVFGPTCDSLDTVLK

EHPLP-DLVDGDWIVFPNMGAYTHCAGSSFNGYDTSDIPT--------------------

-----------------------------------

>Calycanthus_floridus

------------------------------------------------------------

-----------------------------------VKG-KVVSLGKNSKE----------

----GVIELIQSIISKKH--EVKD------PFYVLDLGVLVGLMGKWYHGLANVRPFYAV

KCNPEPAILSALAALGAGFDCASRAEIEAVLALG-VSASNIVYANPCKAEAQIKYAANVG

VNLTTFDSRDEVEKIRKWHPRCALLLRLKAPDDSG------AQCPLGPKYGA--LPEEVV

PLLQAAHAARLTVAGVSFHVGSGATH--VRAYHGAIAAAKEVFNAAA-RLGMARMHVLNI

GGGFISG------PRFDQATATIKAAIQAYFPNEPG----LKLMAEPGRFFAETALTLAT

NIIGKRVRGDL---------------REYWINDGIYGSMNCILYDHATVTAIPLACNSN-

----RSNPTCRG------LRTYTS---------------------TVFGPTCDALDTVLT

AHQLP-ELYVNDWLIFPNMGAYTASAGSNFNGFSTSAISTHLAYS---------------

-----------------------------------

>Laurelia_sempervirens

------------------------------------------------------------

-----------------------------VMAAPGVKGKKVSSLGKNSKE----------

----GVIDLIQTIISKKQ--DVKD------PFYVLDLGVLVGLMEKWNHGLANVRPFYAV

KCNPDPAFLGALAALRAGFDCASRAEIEAVLAIG-VSPDQIVYANPCKAEAQIKYAGSVG

VNLTTFDSRDEIEKIRKWHPRCELLLRLKAPDDSG------ARCPLGPKYGA--LPEEVA

PLLQAAQAARLNVVGVSFHVGSGATH--AQAYRGAIAAVKAVFDAAS-RLGMPRMRVLNI

GGGFTAG------PQFYEAVSAVKAALQSYFPNEPS----LTLMAEPGRFFAETAFTLAT

NIIGKRVRGNL---------------REYWINDGIYGSMNCILYDHATVTAVPLAVTSN-

----RANPNCRG------LRTYPS---------------------TVFGPTCDALDTVLT

DHQLP-ELQVNDWLVFPNMGAYTASAGSNFNGFSTAAISTHLAYSS--------------

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96

-----------------------------------

>Cinnamomum_camphora

------------------------------------------------------------

-----------------------------VLAAPGVKGKKVSNLGKKSKE----------

----GVIELIQSIINKKQ--EVKD------PFYVLDLGVLVGLMDKWARGLPNVRPFYAV

KCNPEPAILGALAALGAGFDCASRAEIEAVMALG-VPAGQIVYANPCKAEAQIKYAAGVG

VNLTTFDSREEIEKLRRWHPRCALLLRLKAPEDSG------ARCPLGPKYGA--LPEEVI

PLLQAAHTARLVVKGVSFHVGSGAMH--ARAYRVAIAAAKTVFDTAA-RLNMPKMHVLNI

GGGFTAG------PQFDEAATAIKAALQAYFPNEPG----LTLMAEPGRFFAETTFTLAT

NIIGKRVRGDL---------------REYWINDGIYGSMNCILYDHATISAMPLACASN-

----PGNPACRG------LRTYGS---------------------TVFGPTCDALDTVLT

GHQLP-ELQVNDWLVFPNMGAYTASAGSNFNGFCTSAIPTHLACSSSN------------

-----------------------------------

>Atrichum_angustatum

------------------------------------------------------------

------------------------------------------------------------

--------------QKRG---------LQDPFYVLDLGLLIELYQGWIQSIPRVKPFYAV

KCSPDPALLSTLATLGAGFDCASKAEISQVLAIG-VPSERIIFANPCKMHGHIKYAASVG

VNIMTFDCEMEVHKVKSCHPDAVLLLRIRADDRGA-------RCPLGVKYGA--MMCEVE

GLLRVAHECNVPVAGVSFHIGSGATD--ANSFTDAIAAAREVFDIAA-NLCLPAMDILDI

GGGFTAGC--SGGLSFLDAAAAVNSALNTYFPPEMG----VTIIAEPGRYFAESPSTLAT

MVMGKRVRGNL---------------NEYWINDGIYGSMNCLLYDHAVLKYRPFACTSQ-

----ESTGN---FDC-ESLALHNS---------------------TVFGPTCDGLDTVLR

NASLP-NLDVGDWIVFPNMGAYTAAAGSSFNGFATSEIPTFYVLSN--------------

-----------------------------------

>Andreaea_rupestris

------------------------------------------------------------

------------------------------------------------------------

-SQTEVDSFILSIAQKRG---------MEGPFYVLDLGLLVQLFHLWVKALPRVKPFYAV

KCSPDPALLSTLAALGAGFDCASKAEIAQVLALG-VPCERVLFANPCKMPSHVTYAASVG

VNIMTFDCESEVHKVRASHPNAVLLLRIRTDDRGA-------RCPLGVKYGA--LMSEVE

PLLTVAADHGVPVAGVSFHIGSGATD--ALSFTDAIAAAREVFDIAA-RLQLPPMDILDI

GGGFTAGV--SGALTFVDAAAAVNAALEKYFPVDMG----ITIIAEPGRYFAESPSTLAT

MVMSKRVRGSL---------------KEYWINDGIYGSMNCLLYDHALLGYRPLAVASQ-

----EKTAN---VSC-LGLPLHNS---------------------TVFGPTCDGLDTVLR

GALLP-ELAINDWVVFPNMGAYTAAAGSSFNGFATSEIPTFYTFSN--------------

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>Sphagnum_palustre

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-----IDSFIRSTIQKHG---------MGDAFYVLDLGLLVRLFQGWVQAMPRVRPFYAV

KCSPDRALLTTLAALGAGFDCASKAEISQVLDLG-VATDRIVFANPCKMQSHVAYAASVG

VNLTTFDSESEVHKVKAHHPGAVLLLRIRTDDRGA-------RCPLGVKYGA--LMYEVE

HLLRVADNLHVPVAGVSFHIGSGATA--AFSFTDAIAAAREVFDISE-RLGLPKMHILDI

GGGFTSGC--SGSLKFSDAAEAVNDALDSYFPLEMG----VKIIAEPGRYFAETPSTLAT

TVIGKRVRGEV---------------KEYWINDGIYGSMNCLLYDHAVLKYRPLICLAD-

----ESKNNNCHGDC-GSLPTHNS---------------------TVFGPTCDGLDTVLQ

GASLP-DLSIGDWIIFPDMGAYTAAAGSSFNGFSMSDIPTFYVFS---------------

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