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Experience Teaching - 10 Years Research - 10 Years Research Interest Cancer Biology, Clinical Biochemistry Molecular Oncology Lab Dr. V. Manju M.Sc., M.Phil., Ph.D Assistant Professor Department of Biochemistry Periyar University Salem 636011, Tamil Nadu, India

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Page 1: Molecular Oncology Lab - Periyar University,Salem · Biotechnology. 2(1); 11. Google Scholar 0.6 2014 18.24. Molecular docking and bio-availability studies of caffine and caffeic

Experience Teaching - 10 Years

Research - 10 Years

Research Interest Cancer Biology, Clinical Biochemistry

Molecular Oncology Lab

Dr. V. Manju M.Sc., M.Phil., Ph.D

Assistant Professor Department of Biochemistry

Periyar University

Salem – 636011, Tamil Nadu, India

Page 2: Molecular Oncology Lab - Periyar University,Salem · Biotechnology. 2(1); 11. Google Scholar 0.6 2014 18.24. Molecular docking and bio-availability studies of caffine and caffeic

Major Research Projects Completed/ Ongoing

S.No. Title of the Project Name of the funding

agency

Duration Budget

1. Synergistic effects of selected

anti-cancer drugs with vitamin-E against colon carcinogenesis

models

UGC 2012-

2015

13,36,300.00

2. Molecular and biochemical

approach to the anti-carcinogenic effect of

eriodictyol, a dietary flavonoid in DMH induced colon carcinogenesis

DST 2013-

2016

18,90,000.00

3. Pilot studies on microwave conversion of eggshell in to

nanostructured hydroxyapatite for biomedical applications and design and fabrication of

continuous flow microwave reactor for scaling up the

process.

DST

(Co-PI)

2016-2019

54,10,143.00

Page 3: Molecular Oncology Lab - Periyar University,Salem · Biotechnology. 2(1); 11. Google Scholar 0.6 2014 18.24. Molecular docking and bio-availability studies of caffine and caffeic

Students Fellowship

S.

No.

Name of the

Scholar Title of the Research

Fellowships

1. M. Murugesan

Cardioprotective role of the flavonoid

luteolin on biochemical and molecular

biological variables on isoproterenol

induced myocardial infarction in rats

URF

2. R. Revathi

Modulatory influence of umbelliferone

with vitamin C on diethylnitrosamine

induced hepatocellular carcinoma in

rats

ICMR-SRF

3. N. Karthi

Synergistic effects of selected

anticancer drugs with vitamin E

against colon carcinogenesis models

UGC-MRP-

SRF

4. P. Mariyappan

Molecular and biochemical approach

to the anti-carcinogenic effect of

eriodictyol, a dietary flavonoid in

DMH induced colon carcinogenesis

DST-SERB-

SRF

6. M.Venkatachalam

Pilot studies on microwave conversion

of eggshell in to nanostructured

hydroxyapatite for biomedical

applications and design and

fabrication of continuous flow

microwave reactor for scaling up the

process

DST-SRF

7. T. Kalaiyarasu

Molecular mechanism underlying the

anticancer potential of orientin in

colorectal cancer models

URF

8. G. Mydhili

Understanding the biochemical and

molecular mechanism underlying the

anti-cancer effect of Kaempferitrin

against colon carcinogenesis

URF

Page 4: Molecular Oncology Lab - Periyar University,Salem · Biotechnology. 2(1); 11. Google Scholar 0.6 2014 18.24. Molecular docking and bio-availability studies of caffine and caffeic

Details of Publications: In Press/ Accepted/ Published

S.N

o

Title/ Author Index Impact

Factor

Year

1. Orientin, a flavanoid, mitigates 1, 2

dimethylhydrazine-induced colorectal lesions in

Wistar rats fed a high-fat diet.

Kalaiyarasu T, Karthi N, Mariyappan P and

Manju V

Toxicology Reports. (Elsevier) 5 (977-987)

https://doi.org/10.1016/j.toxrep.2018.09.004

SCI

SNIP-

0.808

- 2018

2. Orientin mitigates 1,2-dimethylhydrazine induced

lipid peroxidation, antioxidant and

biotransforming bacterial enzyme alterations in

experimental rats.

Kalaiyarasu T, Karthi N, Kandakumar S,

Mariyappan P and Manju V.

Journal of Cancer Research and Therapeutics.

SCIE 0.84 2018

3. Orientin, a C-glycosyl dietary flavones,

suppresses colonic cell proliferation and mitigates

NF-kB mediated inflammatory response in 1, 2-

dimethyl hydrazine-induced colon carcinogenesis.

Kalaiyarasu T and Manju V

Biomedicine and Pharmacotherapy.

(Elsevier)96; 1253-1266.

SCI 3.457 2017

4. An evaluation of antioxidant potential of flavonoid

eriodictyol in isoproterenol-induced myocardial

infarction in rats.

Preethi H, Mariyappan P and Manju V

Indian Journal of Pharmaceutical Education

and Research. 4 (51) 603-612.

Scopus 0.3 2017

Page 5: Molecular Oncology Lab - Periyar University,Salem · Biotechnology. 2(1); 11. Google Scholar 0.6 2014 18.24. Molecular docking and bio-availability studies of caffine and caffeic

5. 1. Formulation and evaluation of isorhamnetin

loaded poly lactic-co-glycolic acid nanoparticles.

Kandakumar S, Manju V.

2. Asian Journal of Pharmaceutical and Clinical

Research. 10(11); 177-181.

SCI 0.4 2017

6. 3. Pharmacological applications of isorhamnetin: A

short review.

Kandakumar S and Manju V.

4. International Journal of Trend in Scientific

Research and Development. 1(4); 672-678.

Scopus 0.15 2017

7. 5. In silico molecular docking analysis of orientin, A

potent glycoside of luteolin against BCL-2 family

proteins.

6. Kalaiyarasu T, Karthiga A, Karthi N, Shanmugam

R, Ravi C, Sanjeev Kumar S and Manju V.

7. Journal of Chemical and Pharmaceutical

Research. 9(5);65-72

Scopus 0.15 2017

8. 8. Exploration of cell cycle regulation and

modulation of the DNA methylation mechanism of

pelargonidin: Insights from the molecular

modeling approach.

Karthi N, Karthiga A, Kalaiyarasu T, Stalin A and

Manju V. Computational Biology and

Chemistry. (Elsevier) 70:175-185.

SCI 1.33 2017

9. In silico docking studies on kaempferitrin with

diverse inflammatory and apoptotic proteins

functional approach towards the colon cancer.

Mydhili G, Mariyappan P and Manju V.

International Journal of Pharmacy and

Pharmaceutical Science. 9(9), 99-204.

Scopus 0.45 2017

Page 6: Molecular Oncology Lab - Periyar University,Salem · Biotechnology. 2(1); 11. Google Scholar 0.6 2014 18.24. Molecular docking and bio-availability studies of caffine and caffeic

10. Effect of eriodictyol on preneoplastic lesions,

oxidative stress and bacterial enzymes in 1,2-

dimethyl hydrazine-induced colon carcinogenesis.

Mariyappan P, Kalaiyarasu T and Manju V.

Toxicology Research. (RSC) 6, 678-692.

SCIE 1.969 2017

11. Computational studies on different types of

apoptotic proteins docked with a dietary flavonoid

eriodictyol in colon cancer.

Mariyappan P, Karthi N and Manju V.

Asian Journal of Pharmaceutical and Clinical

Research. 10(1); 223-226.

Scopus 0.48 2017

12. Pelargonidin induces apoptosis and cell cycle

arrest via a mitochondria mediated intrinsic

apoptotic pathway in human colorectal

adenocarcinoma HT29 cells.

Karthi N, Kalaiyarasu T, Kandakumar S,

Mariyappan P and Manju V.

RSC Advances. 6, 45064-45076.

SCIE 3.28 2016

13. 9. In vitro assessment of antioxidant and

antibacterial activity of green synthesized silver

nanoparticles from Digitaria radicosa leaves.

10. Kalaiyarasu T, SharmilaGowri V and Manju V.

11. Asian Journal of Pharmaceutical and Clinical

Research. 9(1); 297-302.

Scopus 0.48 2016

14. 12. Anti-inflammatory and proapoptotic effects of

umbelliferone in colon Carcinogenesis.

13. Ragunath M, Selvaraj N and Manju V.

14. Human and Experimental Toxicology. 35(10);

1041-1054.

PubMed:

MEDLINE

1.84 2016

Page 7: Molecular Oncology Lab - Periyar University,Salem · Biotechnology. 2(1); 11. Google Scholar 0.6 2014 18.24. Molecular docking and bio-availability studies of caffine and caffeic

15 15. Umbelliferone with vitamin C modulates lipid

profile indices in diethylnitrosamine induced

hepatocellular carcinoma.

Revathi R and Manju V.

16. Journal of Biological and Scientific Opinion.

17. 2 (6).

Google

Scholar

- 2014

16. 18. Synthesis and characterization of silver

nanoparticles using hydnocarpus alpina, its

application as a potent antimicrobial and

antioxidant agent – A novel study.

19. Kandakumar S, Sathya V and Manju V.

20. International Journal of ChemTech Research.

6(11); 4770-4776.

Google

Scholar

0.3 2014

17. 21. Synergistic effects of selected anticancer drugs

with vitamin-E against HT-29 human

adenocarcinoma cell lines.

22. Karthi N and Manju V.

23. Indian Journal of Research in Pharmacy and

Biotechnology. 2(1); 11.

Google

Scholar

0.6 2014

18. 24. Molecular docking and bio-availability studies of

caffine and caffeic acid compounds with regulated

proteins.

Nadanasabapathy S and Manju V.

Journal of Biology and Scientific Opinion. 2(1).

Google

Scholar

- 2014

19. 25. Synergistic and individual effects of umbelliferone

with 5-flurouracil on tumor markers and

antioxidant status of rat treated with 1,2-

dimethylhydrazine. Ragunath M and Manju V.

26. Biomedicine and Aging Pathology. (Elsevier)

3(4); 219-227.

SCI 1.1 2013

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20. 27. In vitro free radical scavenging activity and

bioavailability of dietary compounds caffeine,

caffeic acid and their combination.

28. Nadanasabapathy S, Rufia Sherin Mary J and

Manju V.

29. International Food Research Journal. 20(6);

3159-3165.

JCR 0.5 2013

21. 30. Effects of umbelliferone on lipid peroxidation and

antioxidant status in diethylnitrosamine induced

hepatocellular carcinoma.

31. Revathi R and Manju V.

32. Journal of Acute Medicine. (Elsevier) 3(3);

33. 73-82.

SCI 0.3 2013

22. 34. Antiproliferative and apoptotic effects of naringin

on diethylnitrosamine induced hepatocellular

carcinoma in rats.

35. Prabu T and Manju V.

36. Biomedicine and Aging Pathology. (Elsevier)

3(2); 59-64.

SCI 1.1 2013

23. 37. Luteolin promotes mitochondrial protection

during acute and chronic periods of isoproterenol

induced myocardial infarction in rats.

38. Murugesan M and Manju V. The Egyptian Heart

Journal. (Elsevier) 65(4); 319-327.

SNIP-

0.23

0.23 2013

24. 39. Luteolin a dietary flavonoid attenuates

isoproterenol-induced myocardial oxidative stress

in rat myocardium: An in vivo study.

40. Murugesan M and Manju V.

41. Biomedicine and Preventive Nutrition.

(Elsevier) 159-164.

SCI 1.1 2013

Page 9: Molecular Oncology Lab - Periyar University,Salem · Biotechnology. 2(1); 11. Google Scholar 0.6 2014 18.24. Molecular docking and bio-availability studies of caffine and caffeic

25. 42. Synergitic and individual effects of umbelliferone

with 5-flurouracil on the status of lipid

peroxidation and antioxidant defense against 1,

2-dimethylhydrazine induced rat colon

carcinogenesis.

43. Ragunath M, Prabu T, Nadanasabapathy S,

Revathi R and Manju V.

44. Biomedicine and Preventive Nutrition.

(Elsevier) 74-82.

SCI 1.1 2013

26. 45. Antioxidant potential of naringin – a dietary

flavonoid in N-Nitrosodiethylamine induced rat

liver carcinogenesis.

46. Prabu T, Ragunath M and Manju V.

47. Biomedicine and Preventive Nutrition.

(Elsevier) 2(3): 193-202.

SCI 1.1 2012

27. 48. Protective role of black cumin (Nigella sativa) on

isoproterenol induced myocardial infarction in

rats.

Murugesan M, Ragunath M, Prabu T,

Nadanasabapathy S, Sakthivel M and Manju V.

International Journal of Pharmacology and

Clinical Sciences. 1: 45-53.

Google

Scholar

- 2012

28. 49. Effect of luteolin on lipid peroxidation and

antioxidants in acute and chronic periods of

isoproterenol induced myocardial infarction in

rats.

50. Murugesan M and Manju V.

51. Journal of Acute Medicine. (Elsevier) 2(3):

52. 70-76.

53.

SCI 0.3 2012

Page 10: Molecular Oncology Lab - Periyar University,Salem · Biotechnology. 2(1); 11. Google Scholar 0.6 2014 18.24. Molecular docking and bio-availability studies of caffine and caffeic

29. 54. Protective role of fenugreek on isoproterenol

induced myocardial infarction in rats.

55. Murugesan M, Ragunath M, Nadanasabapathy S,

Revathi R and Manju V.

International Research Journal of Pharmacy.

3(2): 211-216.

Scopus 0.75 2012

30. Protection against azaserine induced pancreatic

cancer rats by Phyllanthus amarus: A preliminary

study.

Revathi R, Murugesan M and Manju V

Journal of Biochemical Technology. 3(4):

331-335.

SCI 0.94 2012

31. Cardioprotective effect of fenugreek on

isoproterenol induced myocardial infarction in

rats.

Murugesan M, Revathi R and Manju V.

Indian Journal of Pharmacology. 43(5):

516-519.

SCIE 0.9 2011

32. Cardioprotective effect of black cumin on

isoproterenol induced myocardial infarction in

rats. Ragunath M, Murugesan M, Sakthivel M

and Manju V.

Journal of Pharmacy Research. 4(7):

2040-2044.

Google

Scholar

0.5 2011

33. In vitro antioxidant, antimicrobial, anti-

inflammatory, anthelmintic activity and

phytochemical analysis of Indian medicinal

spices. Manju V, Revathi R and Murugesan M.

Research Journal of Pharmacy and

Technology. 4(4): 596-599.

Scopus 0.21 2011

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34. Effect of ginger on lipid peroxidation and

antioxidant status in 1, 2-dimethylhydrazine

induced experimental colon carcinogenesis.

Manju V and Nalini N.

Journal of Biochemical Technology. 2(2):

161-167.

Thomson

Reuters-

Web of

Science

(ESCI)

0.94 2010

35. Effect of luteolin on glycoproteins metabolism in

1, 2-dimethylhydrazine induced experimental

colon carcinogenesis.

Manju V and Nalini N.

Journal of Biochemical Technology. 1(2):

57-61.

Thomson

Reuters-

Web of

Science

(ESCI)

0.94 2009

36. Protective role of luteolin in 1, 2-

dimethylhydrazine induced experimental colon

carcinogenesis.

Manju V and Nalini N.

Cell Biochemistry and Function. 25(2):

189-194.

SCI 2.186 2007

37. Hypolipidemic effect of ginger in 1,2-dimethyl-

hydrazine-induced experimental colon

carcinogenesis.

Manju V, Viswanathan P and Nalini N.

Toxicology Mechanisms and Methods. 16(8):

461-472.

SCI 1.994 2006

38. Effect of ginger on bacterial enzymes in 1, 2-

dimethylhydrazine induced experimental colon

carcinogenesis.

Manju V and Nalini N.

European Journal of Cancer Prevention. 15(5):

377-383.

JCR 2.886 2006

Page 12: Molecular Oncology Lab - Periyar University,Salem · Biotechnology. 2(1); 11. Google Scholar 0.6 2014 18.24. Molecular docking and bio-availability studies of caffine and caffeic

39. Effect of spices on lipid metabolism in 1, 2-

dimethylhydrazine - induced rat colon

carcinogenesis.

Nalini N, Manju V and Menon VP.

Journal of Medicinal food. 9(2): 237-245.

SCIE 1.954 2006

40. Chemopreventive efficacy of ginger, a naturally

occurring anticarcinogen during the initiation,

post-initiation stages of 1,2-dimethylhydrazine-

induced colon cancer.

Manju V and Nalini N.

Clinica Chimica Acta. (Elsevier) 358(1-2): 60-67.

Elsevier

BIOBASE

2.926 2005

41. Rat colonic lipid peroxidation and antioxidant

status: The effects of dietary luteolin on 1, 2-

dimethylhydrazine challenge.

Manju V, Balasubramaniyan V and Nalini N.

Cellular and Molecular Biology Letters. 10(3):

535-551.

SCIE 1.75 2005

42. Chemopreventive potential of luteolin during

colon carcinogenesis by 1, 2-dimethyl hydrazine.

Manju V and Nalini N.

The Italian Journal of Biochemistry. 54(3-4):

268-275.

Scopus 0.39 2005

43. Effect of coconut cake on the bacterial enzyme

activity in 1, 2-dimethyl hydrazine induced colon

cancer.

Nalini N, Manju V and Menon VP.

Clinica Chimica Acta. (Elsevier) 342(1-2):

203-210.

Elsevier

BIOBASE

2.926 2004

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44. Lipid profile in mice fed a high-fat diet after

exogenous leptin administration.

Kalaivani S and Manju V and Nalini N.

Polish Journal of Pharmacology. 55(5):

763-769.

Scopus 1.25 2003

45. Effect of leptin administration on plasma and

tissue lipids in alcohol induced liver injury.

Balasubramaniyan V and Manju V and Nalini N.

Human and Experimental Toxicology. 22(3):

149-154.

PubMed:

MEDLIN

E

1.84 2003

46. Circulating lipid peroxidation and antioxidant

status in cervical cancer patients: A case-control

study.

Manju V, Kalaivani Sailaja and Nalini N.

Clinical Biochemistry. (Elsevier) 35(8): 621-625.

Elsevier

BIOBASE

2.584 2002

47. Oxidative stress and tumor markers in cervical

cancer patients.

Manju V, Balasubramanian V and Nalini N.

Journal of Biochemistry, Molecular Biology

and Biophysics. 6(6): 387-390.

Pubmed:

Medline

1.09 2002

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International & National Seminars/ Conferences Attended

1. Two days national seminar on Recent Advances in Microbial Technology

for Renewable Energy, Bioremediation, Health and Sustainable

Agriculture (RAMT for REBHSA-2018). Periyar University, Salem, Tamil

Nadu. 24th -25th January 2018.

2. TNSCST-DIT sponsored workshop cum Training Programme on Simplified

and Innovative Technology for the large scale Cultivation of Oyster

Mushrooms. Periyar University, Salem, Tamil Nadu 11th -15th December

2017.

3. National seminar on New Horizons in Plant Biotechnology (NHPB-2017).

Periyar University, Salem, Tamil Nadu 06th December 2017.

4. International Conference on Science, Engineering and Technology.

VIT University. Vellore, Tamilnadu. 06-07 November 2017.

5. Workshop on “Food Safety Regulations for Institutional Food

Establishments”, Department of Food Science and Nutrition, Periyar

University, Salem, Tamilnadu, 22nd December 2016.

6. National conference on “Emerging Trends in Therapeutic Enzymes

production” Indo-American Hybrid seeds (India) PVT. Ltd, Bangalore,

Karnataka, 19th October 2016.

7. International seminar on “Perspectives in Modern Biology” Department of

Zoology, Periyar University, Salem, Tamilnadu, 2nd September 2016.

8. National Conference on “The Role of State Private Universities in

Fulfilling the Aspirations of the Stakeholders: Present and Future”,

Forum of former vice chancellors of Karnataka state universities, Bangalore,

4th June 2016.

9. Internal quality assurance cell (IQAC) sponsored seminar on “World Health

Day”, Periyar University, Salem, Tamilnadu, on 7th April 2016.

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10. Workshop on “Curriculum Enhancement in Higher Education”, IQAC,

Periyar University, Salem, Tamilnadu, 28th-29th March 2016.

11. E=MC2, “Ever mass competitive champions” on Department of Physics,

Periyar University, Salem, Tamilnadu,14th March 2016.

12. IQAC Sponsored Seminar on the “World Wildlife Day”, Periyar University,

Salem, Tamilnadu, 3rd March 2016.

13. Workshop on “RAPD and PCR Techniques”, Department of Biochemistry,

Periyar University, Salem, Tamilnadu, 16th & 17th February 2016.

14. National Conference on “Experimental therapeutics and Clinical

Research”, Department of Biochemistry, Periyar University, Salem,

Tamilnadu, 24th February 2016.

15. Visiting Faculty Programme - A Short Term Course on “Animal

Experimental in Nutrition”, Department of Food Science and Nutrition,

Periyar University, Salem, Tamilnadu, 27th-29th January 2016.

16. National Conference on “New Horizon of Nanotechnology in Bioscience’’,

Department of Biochemistry, Periyar University, Salem, Tamilnadu, 7th & 8th

January 2016.

17. National Workshop on “Nanotechnology for Biologists”, Department of

Zoology, School of Life Sciences, Periyar University, Salem, Tamilnadu,

6th & 8th January 2016.

18. National Seminar on “Food and Nutrition- A challenge to the food

safety”, Garden City College of Science and Management Studies,

Bangalore, Karnataka, 23rd September 2015.

19. National Conference on “New Horizon of Nanotechnology in Bioscience-

2016” (NHNBS-2016), Department of Biochemistry, Periyar University,

Salem, Tamilnadu, 7th_8th January 2015.

20. Workshop on “Exploratory Analysis of Biological Data using

R-Programme”, School of Biosciences, Periyar University, Salem,

Tamilnadu, 17th December 2015.

21. IQAC Seminar on “Modernisation in Higher Education to Address the

Social Needs”, Periyar University, Salem, Tamilnadu, 4th November 2015.

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22. National Conference on “Biosafety for Health Security”, (NCBHS 2015),

Department of Zoology, Periyar Government Arts College, Cuddalore, Tamil

Nadu. 23rd and 24th July 2015.

23. IQAC Sponsored seminar on “Qualitative Enhancement of Teaching and

Learning Process”, Periyar University, Salem, Tamilnadu, 19th October

2015.

24. National Seminar on “Life Science for Nation Building”, Department of

Zoology, School of Life Sciences, Periyar University, Salem, Tamilnadu,

27th & 28th February 2015.

25. Workshop on “Project Writing Skills and Funding Agencies”, Periyar

University, Salem, Tamilnadu, 12th February 2015.

26. National Workshop on “Advanced Characterization Techniques” (ACT-

2015). Department of Chemistry, Periyar University, Salem, Tamilnadu,

29th & 30th January 2015.

27. Faculty Development Programme (FDP) on “Attributes of Holistic

Teaching”, Periyar University, Salem, Tamilnadu, 17th-20th December 2014.

28. International Conference on “Physiology and Medicine”. Periyar University, Periyar Palkalainagar, Salem, Tamilnadu, 15th - 17th October

2014.

29. National workshop on Green Initiatives in Energy and Environment” (GIEE-2014) Periyar University, Periyar Palkalainagar, Salem, Tamilnadu,

11th September 2014.

30. International Seminar on “Nanobiotechnology in Cancer Research” (NCR-

2014), Periyar University, Periyar Palkalainagar, Salem, Tamilnadu, 21st July 2014.

31. National Symposium on “Carbohydrates in Human Health”. Periyar

University, Periyar Palkalainagar, Salem, Tamilnadu, 24th January 2014.

32. National seminar on “Current Zoology”. Periyar University, Periyar Palkalainagar, Salem, Tamilnadu, 21st January 2014.

33. National level seminar on “Current Trends in Biodiversity Conservation and Forest Management” (CTBCFM-2014). Periyar University, Periyar

Palkalainagar, Salem, Tamilnadu, 6th & 7th January 2014.

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34. Seminar on “Trends in Protein Engineering”. Periyar University, Periyar Palkalainagar, Salem, Tamilnadu, 21st November 2013.

35. National seminar on “Tissue Engineering and Regenerative Medicine”. Garden City College, Bangalore. 25th September 2013.

36. National Conference on “Frontiers and Challenges in Biological Organometallic Compounds” M.S. Ramaiah Institute of Technology, Bangalore. 20th & 21st June 2013.

37. National Seminar on “Current Trends in Biotechnology” (CTBBN). Periyar University, Periyar Palkalainagar, Salem, Tamilnadu, 11th March 2013.

38. National conference on “Implications and Interventions of

Phytomedicine in Disease Management” (IIPDM-2013) Periyar University, Periyar Palkalainagar, Salem, Tamilnadu, 18th & 19th February 2013.

39. National seminar on “Biotechnological Intervention in Plant and Microbial Interaction for Crop Sustainability” (BPMCS-2013) Periyar University, Periyar Palkalainagar, Salem, Tamilnadu, 30th & 31st January

2013.

40. International Conference on “Phytochemicals in Health and Disease:

Challenges and Future Opportunities” (ICPHD-2013) Annamalai University, Annamalai Nagar, Chidambaram, Tamilnadu, 23rd to 25th January 2013.

41. National conference on “Food Processing and Technology for Health Progression” (NCFPTH-2013) Periyar University, Periyar Palkalainagar, Salem, Tamilnadu, 9th & 10th January 2013.

42. International conference on “Recent Trends in Atherosclerosis and 25th Annual meeting of ISAR”, Annamalai University, Annamalainagar, 1st-3rd

September 2012.

43. UGC sponsored national seminar on “Current Status and Future Prospectus of Plants Therapeutics and Phyto Medicine” (PTPM 2012),

Periyar University, Periyar Palkalainagar, Salem, Tamilnadu, 13th & 14th February 2012.

44. International workshop on “Advanced Food Analytical Techniques”,

Periyar University, Periyar Palkalainagar, Salem, Tamilnadu, January 2012.

45. National seminar on “Enzymes and Biocatalysis. The Versatile Actors:

Current Trends and Future Prospective” (NSEB 2012). Periyar University, Periyar Palkalainagar, Salem, Tamilnadu, 5th & 6th January 2012.

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46. International Symposium on “Function Foods and Health”. Periyar University, Periyar Palkalainagar, Salem, Tamilnadu, 20th November 2011.

47. National conference on “Biopharmaceuticals and Healthcare”. Sri M. Visvesvaraya Institute of Technology, Bangalore, 4th & 5th November 2011.

48. A seminar on “Emerging Trends in Biotechnological Approaches for

Infectious Disease Management”. Department of Biotechnology, Periyar University, Salem-11. November 2010.

49. International conference on “Antioxidants Free radicals in Health –

Nutrition”. Radioprotectors and IV Annual conference of the Society for free radical Research in India (SFRR) Bangalore, Karnataka and January 2005.

50. UGC sponsored National Conference on “Natural Products, in Health”. Annamalai University, Annamalainagar, Tamilnadu, February 2005.

51. SFRR International Conference on “Natural Products, Free Radicals and

Radio protective in Health” Annamalai University, Annamalainagar, Tamilnadu, January 2004.

52. XIV Annual Scientific Meet of “Society of Biological Chemists” (India) Annamalai University, Annamalainagar, Tamilnadu, February 2004.

53. XIII Annual Scientific Meet of “Society of Biological Chemists” (India)

Annamalai University, Annamalainagar, Tamilnadu, February 2003.

54. XII Annual Scientific Meet of “Society of Biological Chemists” (India). Annamalai University, Annamalainagar, Tamilnadu, February 2002.

55. XV Annual Conference of “Society for Atherosclerosis Research”. Tirupati, October 2002.

56. XI Annual Scientific Meet of “Society of Biological Chemists” (India). Annamalai University, Annamalainagar, Tamilnadu, February 2001.

57. X Annual Scientific Meet of “Society of Biological Chemists” (India).

Annamalai University, Annamalainagar, Tamilnadu, February 2000.

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Paper/Posters Presented

1. Mydhili G and Manju V, Poster presentation on Kaempferitrin causes ROS

overproduction, oxidative damage in DNA leading to cell cycle arrest

and apoptosis in human colon HT-29 cells. International Conference on

Phytomedicine. Bharathiar University, Coimbatore, Tamilnadu, India.

29th -31st August 2018.

2. Vanitha S and Manju V, Paper presentation on Investigation on wound

healing potential of Kleinia grandiflora based topical formulation in

swiss albino mice models. International Conference o Phytomedicine.

Bharathiar University, Coimbatore, Tamilnadu, India. 29th -31st August

2018.

3. Mydhili G, Mariyappan P and Manju V, Paper presentation on

Kaempferitrin induces cell cycle arrest and apoptosis in human colon

adenocarcinoma HT-29 cells via PI3k/AKT pathway. International

Conference on Environmental, Genes, Health and Diseases. Bharathiar

University. Coimbatore, India. 22nd – 24th August 2017.

4. Preethi H, and Manju V, Paper presentation on Eriodictyol attenuates

H2O2-induced oxidative stress in H9C2 cell lines An In vitro analysis

using flow cytometer. International Conference on Recent Advances in

Bioresource Technology. Thiruvalluvar University, Vellore, India. 15th -17th

February 2017.

5. Kalaiyarasu T, Karthi N, Elakkiya M.V, Mydhili G and Manju V, Paper

Presentation on Salvianolic acid loaded nanoparticles: Synthesis,

characterization and In Vitro cytotoxicity against MCF-7 Breast cancer

cell line. 104th Indian Science Congress. Tirupati, India. 3rd-7th January

2017.

6. Vaitheeswari B and Manju V, Paper Presentation on Evaluation of

antibacterial activity of green synthesized copper oxide nanoparticles

using Euphorbia hirta leaves extract. 104th Indian Science Congress.

Tirupati, India. 3rd-7th January 2017.

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7. Mydhili G and Manju V, Poster presentation on Green synthesis and

characterization of graphene oxide and GO-Ag nanoparticles using

plumeria rubra: Its applications in antibacterial properties for water

disinfection. International Conference on Environment and Health in

Changing Climate. Bharathidasan University, Tiruchirappalli, India.

14th -16th September 2016.

8. Kalaiyarasu T, Kandakumar S and Manju V, Poster presentation on

PLGA/Chitosan modified lupeol nanoparticles-synthsis,

characterization and in vitro cytotoxicity. International Symposium on

Current Advances in Radiobiology, Stem Cells and Cancer Research. School

of Life Sciences, Jawaharlal Nehru University (JNU) New Delhi, India.

19th-21st February 2015.

9. Mydhili G, Mariyappan P and Manju V, Poster presentation on Protective

effect of Salvianolic acid B against acetic acid induced ulcerative colitis

in experimental mice. International Symposium on Current Advances in

Radiobiology, Stem Cells and Cancer Research. School of Life Sciences,

Jawaharlal Nehru University (JNU) New Delhi, India. 19th-21st February

2015.

10. Mariyappan P and Manju V, Poster presentation on Eriodictyol a dietary

flavonoid inhibits cell proliferation of human colon adenocarcinoma

HT-29 cells. International Symposium on Current Advances in

Radiobiology, Stem Cells and Cancer Research. School of Life Sciences,

Jawaharlal Nehru University (JNU) New Delhi, India. 19th-21st February

2015.

11. Karthi N and Manju V, Poster presentation on An in vitro study on anti-

carcinogenic effect of pelargonidin by G2M phase arrest in HT29 cell

lines. International Symposium on Current Advances in Radiobiology, Stem

Cells and Cancer Research. School of Life Sciences, Jawaharlal Nehru

University (JNU) New Delhi, India. 19th-21st February 2015.

12. Kandakumar S Kalaiyarasu T and Manju V, Poster presentation on

Encapsulation and in vitro Release of Lupeol Nanoparticles Using PLGA

Biodegradable Polymer. International Symposium on Current Advances in

Radiobiology, Stem Cells and Cancer Research. School of Life Sciences,

Jawaharlal Nehru University (JNU) New Delhi, India. 19th-21st February

2015.

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13. Karthi N and Manju V, Paper presentation on An in vitro study on

anticancer property of Pelargonidin and its mechanism of G2/M arrest

in cell cycle via cyclin and Cdks on HT-29 cell lines. International

Conference on Physiology and Medicine (ICPM-2014), Periyar University,

Periyar Palkalainagar, Salem, Tamilnadu, India. 15th - 17th October 2014.

14. Mariyappan P and Manju V, Poster presentation on Green synthesis of

silver nanoparticles using extracts of Ananas comosus. National Level

Conference on Advances in Drug Design, Discovery and Development. Anna

University, BIT campus Tiruchirappalli, Tamilnadu, India. 24th & 25th July

2014.

15. Kalaiyarasu T and Manju V, Poster presentation on Synthesis,

characterization and in vitro antioxidant potential of green silver

nanoparticles from Digitaria radicosa. National Level Conference on

Advances in Drug Design, Discovery and Development. Anna University, BIT

campus Tiruchirappalli, Tamilnadu, India. 24th & 25th July 2014.

16. Kandakumar S, Sathya V and Manju V, Poster presentation on Synthesis

and characterization of silver nanoparticles using Hydnocarpus alpine,

its application as a potent antimicrobial and antioxidant agent a novel

study. National Level Conference on Advances in Drug Design, Discovery

and Development. Anna University, BIT campus Tiruchirappalli, Tamilnadu,

India. 24th & 25th July 2014.

17. Karthi N and Manju V, Paper presentation on Characterization and

evaluation of anticarcinogenic activity of green synthesized AgSNPs

from Tragia bicolor: an in vitro study. International Conference on

Materials and Characterization Techniques. VIT University, Vellore, India.

10th-12th March 2014.

18. Srivalli T, Priyadharsini M and Manju V, Poster presentation on Evaluation

of combined and individual effects of silver nanoparticles from vitamin

C and luteolin on HeLa cell lines. International Conference on Materials

and Characterization Techniques. VIT University, Vellore, India. 10th-12th

March 2014.

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19. Kalaiyarasu T, Sharmila Gowri V and Manju V, Poster presentation on

Synthesis, characterization and in vitro antioxidant potential of green

silver nanoparticles from Digitaria radicosa. International Conference on

Materials and Characterization Techniques. VIT University, Vellore, India.

10th-12th March 2014.

20. Kandakumar S, Sathya V and Manju V, Poster presentation on Synthesis,

characterization of silver nanoparticles using hydnocarpus alpine, its

application as potent antimicrobial and antioxidant agent. International

Conference on Materials and Characterization Techniques. VIT University,

Vellore, India. 10th-12th March 2014.

21. Mariyappan P and Manju V, Poster presentation on Studies on the

antioxidant and free radical scavenging activities of Quercetin and

vitamin E. National Conference on Frontiers and Challenges in Biological

Organometallic Compounds (FCBOM-2013), M.S. Ramaiah Institute of

Technology, Bangalore, India. 20th & 21st June 2013.

22. Manju V, Paper Presentation on Effects of ginger on bacterial enzymes

in 1, 2 Dimethylhydrazine induced experimental colon carcinogenesis.

International conference on Phytochemicals in Health and Disease:

Challenges and Future Opportunities (ICPHD-2013), Annamalai University,

Annamalainagar, India. 23rd-25th January 2013.

23. Ragunath M and Manju V, Paper presentation on Synergistic and

individual effects of umbelliferone with 5-flurouracil on the status of

lipid peroxidation and antioxidant defense against 1, 2-

dimethylhydrazine induced rat colon carcinogenesis. International

conference on Phytochemicals in Health and Disease: Challenges and

Future Opportunities (ICPHD-2013), Annamalai University,

Annamalainagar, India. 23rd-25th January 2013.

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24. Revathi R and Manju V, Poster presentation on Preventive effect of

umbelliferone against diethyl-nitrosamine induced hepatocellular

carcinoma in male wistar rats. International conference on

Phytochemicals in Health and Disease: Challenges and Future

Opportunities (ICPHD-2013), Annamalai University, Annamalainagar, India.

23rd-25th January 2013.

25. Karthi N and Manju V, Poster presentation on Synergistic effects of

selected anti – cancer drugs with vitamin-E on colon carcinoma: An in

vitro study. International conference on Phytochemicals in Health and

Disease: Challenges and Future Opportunities (ICPHD-2013), Annamalai

University, Annamalainagar, India. 23rd-25th January 2013.

26. Murugesan M and Manju V, Paper presentation on Luteolin a dietary

flavonoid attenuates isoproterenol – induced myocardium: An In vivo

study. International conference on Phytochemicals in Health and Disease:

Challenges and Future Opportunities (ICPHD-2013). Annamalai University,

Annamalainagar, India. 23rd-25th January 2013.

27. Revathi R and Manju V, Paper presentation on Protective activity of

umbelliferone against N- nitrosodiethylamine induced hepatocellular

carcinoma in wistar rats. National conference on Current Scenario and

Emerging Trends in Hepatocellular Diseases (NC-HepCD-2012). Pondicherry

University, Pondicherry, India. 5th -6th October 2012.

28. Prabu T and Manju V, Paper presentation on Antioxidant potential of

naringin – a dietary flavonoid, in N-nitrosodiethylamine induced rat

liver carcinogenesis. National conference on Current Scenario and

Emerging Trends in Hepatocellular Diseases (NC-HepCD-2012). Pondicherry

University, Pondicherry, India. 5th - 6th October 2012.

29. Murugesan M and Manju V, Paper presentation on “Effect of luteolin on

lipid peroxidation and antioxidant in acute and chronic periods of

isoproterenol induced myocardial infarction on rats”. International

Conference on Recent Trends in Artherosclerosis & 25th annual meeting of

ISAR 2012. Annamalai University, Annamalainagar, India. 1st-3rd September

2012.

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30. Prabu T and Manju V, Poster presentation on Antioxidant potential of

narigin-a dietary flavonoid, in N-nitrosodiethlamine induced rat liver

carcinogenesis. International Centre for Intellectual Training and

Empowerment (ORIBIO-2012). Hotel Mascot, Trivandrum, India.

29th February 2012.

31. Murugesan M, Ragunath M, Nadanasabapathy and Manju V, Poster

presentation on Cardioprotective effect of luteolin on isoproterenol

induced myocardial infarction in rats. International Centre for Intellectual

Training and Empowerment (ORIBIO-2012). Hotel Mascot, Trivandrum,

India. 29th February 2012.

32. Karthi N and Manju V, Poster presentation on Efficiency of aqueous

extract of Aigle Marmelos in protecting the CCl4 mediated liver

inflammation in wistar rats. International Centre for Intellectual Training

and Empowerment (ORIBIO-2012). Hotel Mascot, Trivandrum, India.

29th February 2012.

33. Karthi N and Manju V, Paper presentation on Amelorative effect of

thiourea on salt stress induced in maize (ZEA MAYS). National seminar

on ‘Enzymes and Biocatalysis, The Versatile Actors: Current Trends and

Future Perfectives (NSEB 2012) Periyar University, Periyar Palkalainagar,

Salem, Tamilnadu, India. 5th and 6th January 2012.

34. Prabu T, Ragunath M and Manju V, Paper presentation on Antioxidant

effect of Naringin against DEN induced hepatocellular carcinoma.

National Seminar on Current Innovations and Recent Trends in Cancer

Biology (CIRTCB-2011). Periyar University, Salem, Tamilnadu, India.

24th October 2011.

35. Murugesan M, Revathi R and Manju V, Poster presentation on Role of

fenugreek on isoproterenol induced myocardial infarction in rats.

International conference on Food and Nutraceuticals for Nutrition and

Health: Technology and Delivery (ICFAN-2011). Periyar University, Periyar

Palkalainagar, Salem, Tamilnadu, India. 20th-22nd January 2011.

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36. Revathi R, Murugesan M and Manju V, Paper presentation on

Chemopreventive effect of phyllanthusamarus on azaserine induced

pancreatic cancer rats. International conference on Food and

Nutraceuticals for Nutrition and Health: Technology and Delivery ICFAN-

2011. Periyar University, Periyar Palkalainagar, Salem, Tamilnadu, India.

20th-22nd January 2011.

37. Ragunath M and Manju V, Paper presentation on Role of

Cissusquadrangularis in rats fed with hyperlipidemic diet. International

conference on Natural Products and Biomedical Technology (ICNPBT-2011).

Annamalai University, Annamalainagar, Tamilnadu, India.10th-12th January

2011.

38. Murugesan M, Revathi R and Manju V, Paper presentation on Role of

Solanumtrilobatum on cyclosporine A induced oxidative damage in

rats. International conference on Natural Products and Biomedical

Technology ICNPBT-2011. Annamalai University, Annamalainagar,

Tamilnadu, India. 10th-12th January 2011.

39. Murugesan M and Manju V, Paper presentation on Cardioprotective role

of Fenugreek on isoproterenol induced myocardial infarction in rats.

International congress on Nutrition in Cardiovascular Diseases (Healthy

Heart’ 2010). (BPCON-2010). Annamalai University, Annamalainagar,

Tamilnadu, India. 15th - 16th November 2010.

40. Manju V, Paper presentation on Protective role of Black cumin on

isoproterenol induced myocardial infarction in rats. International

congress on Nutrition in Cardiovascular Diseases (Healthy Heart’ 2010).

(BPCON-2010). Annamalai University, Annamalainagar, Tamilnadu,

India.15th - 16th November 2010.

41. Revathi R, Murugesan M and Manju V, Paper presentation on Protection

against azaserine induced pancreatic cancer in rats by a medicinal

plant Phyllanthusamarus: A Preliminary study. National level seminar

on Challenges and Opportunities in Biological Sciences, Muthayammal

college of Arts and Science, (BIOMIC-2010), Rasipuram, Tamilnadu, India.

12th - 13th February 2010.

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42. Murugesan M and Manju V, Paper presentation on Cardioprotective effect

of fenugreek on isoproterenol induced myocardial injury in rats.

National level seminar on Challenges and Opportunities in Biological

Sciences, Muthayammal college of Arts and Science. (BIOMIC-2010),

Rasipuram, Tamilnadu, India. 12th - 13th February 2010.

43. Manju V and Nalini N Poster presentation on Chemo preventive effect of

ginger on circulatory lipid per oxidation and antioxidant status in 1,2-

dimethylhydrazine induced colon cancer. International conference on

Antioxidants and Free Radicals in Health-Nutrition and Radio protectors

and IV Annual conference of the Society for free Radical Research in India

(SFRR), Bangalore, Karnataka, India. 10th-12th January 2005.

44. Manju V and Nalini N, Poster presentation on Oxidative stress and

antioxidant status in cervical cancer patients: A case-control study.

International Conference on Natural Products, Free Radicals and

Radioprotective in Health (NFRH-2004). Annamalai University

Annamalainagar, Tamilnadu, India. 17th-19th January 2004.

45. Manju V and Nalini N, Paper presentation on Circulatory lipid

peroxidation and antioxidant status in cervical cancer patients. XV

Annual Conference of Indian Society for Atherosclerosis Research

(ISARCON-2002). Sri Venkateshwara Institute of Medical Sciences Tirupati,

India. 10th & 11th October 2002.

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Conference Organized

Convener:

Organized the Internal Quality Assurance Cell (IQAC) Sponsored Seminar on

World Cancer Day held on 4th February, 2016 in Periyar University, Salem-

636011.

Organized the National Seminar on Current Innovations and Recent

Trends in Cancer Biology held on 24th October, 2011 in the Department of

Biochemistry, Periyar University, Salem-11.

Organizing Committee member:

National Science Day Celebrations - 2017, Periyar University, Periyar

Palkalainagar, Salem, Tamilnadu, 28th February 2017.

UGC sponsored national seminar on Current status and future prospectus

of plants therapeutics and phyto medicine (PTPM 2012), Periyar

University, Periyar Palkalainagar, Salem, Tamilnadu, 13th & 14th February

2012.

National seminar on Enzymes and Biocatalysis. The Versatile Actors:

Current trends and future prospective (NSEB 2012), Periyar University,

Periyar Palkalainagar, Salem, Tamilnadu, 5th & 6th January 2012.

One day seminar on Biodiversity resources, Management and

Conservation was held on 31st Dec, 2010 at Periyar University, Salem-11.

Special lecture:

Organized the special lecture titled by “Spingolipids on Cancer Biology”

with Dr. P. Thamarai Udhaya Suriyan, Senior scientist, Department of

Biochemistry and Molecular Biology, Hollings cancer center, Medical

University of South Carolina. USA.

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Organized the special lecture titled by “Lysine Specific Demethylase

inhibitors as Epigenetic Modulators” with Dr. P. Boobalan, Post-Doc

Researcher, Department of Drug Discovery and Biomedical Sciences,

Medical University of South Carolina, Charleston, SC, USA.

Life member

Biomedical Engineering Society of India–Manipal Institute

of Technology, Manipal

Society of Biological Chemists, India.

INCITE Science and Technology consortium (ISTC)

SBTI-Cochin University of Science and Technology.

Member for board of studies

Member of PG & Mphil board of studies in Biochemistry at Periyar University, Salem -11.

Member of UG and PG board of studies in Biochemistry (Affiliated colleges) Periyar University, Salem -11.

Member of UG and PG board of studies in Vellalar College for women, Erode-12.

Research Lab Facilities Cell Culture Hood, CO2 Incubator, Deep

Freezer (-20ºC), Blotting Techniques, UV

Spectrophotometer, Micro-refrigerator

centrifuge.

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Examiner for PG/M.Phil

External and Internal examiner for Periyar University examinations for

PG (Both theory and practical) and M.Phil Biochemistry, Periyar

University.

External examiner for PG (practical) for Food science and nutrition,

Periyar University.

External examiner for PG (practical) for Microbiology, Periyar University.

External examiner for conducting M.Phil Microbiology Viva-voce

examinations, Periyar University.

Examiner for evaluating M.Phil thesis for Annamalai University.

External examiner for evaluating M.Phil thesis for Karpagam University.

Examiner for evaluating M.Phil thesis for Bharathiyar University.

External examiner for PG (Practical) for Muthayammal College of arts

and science.

External examiner for PG (Practical) for K.S.R. College of arts and

science.

External examiner and question paper setter for Bharathidhasan

University.

External examiner for evaluating UG theory paper for Vinayaga

Missions University.

Doctoral Committee Member

External doctoral committee member for Ph.D at Vellore Institute of

Technology, Vellore.

External doctoral committee member for Ph.D at Periyar University,

Salem.

External doctoral committee member for Ph.D at Muthayammal College

of arts and science.

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M.Phil/ Ph.D (Completed)

S.

No. M.Phil Ph.D

Registered Submitted

Registered Submitted Awarded

Full

Time

Part

Time

Full

Time

Part

Time

Full

Time

Part

Time

1. 1 29 4 1 - - 8 1

Ph.D. Awarded

S.

No

Name of the Scholar Title of Thesis University Date of

Awarded

1.

T. Prabu Naringin- A flavonone,

attenuates liver carcinogenesis by NF-kB

mediated apoptotic pathway – In vivo and In vitro studies

Periyar 13.11.2013

2. M. Murugesan Cardio Protective role of the flavonoid luteolin on

biochemical and molecular

biological variables in isoproterenol- induced

myocardial infarcted in rats:

An In vivo and In vitro study

Periyar 09.04.2014

3. M. Ragunath Molecular mechanisms underlying chemo preventive

activities of umbelliferone alone and with 5-fluorouracil

on 1,2-Dimethylhydrazine

induced colon carcinogenesis

Periyar 08.08.2014

4. S.Nadanasabapathy Molecular and Biochemical

approach to the anticancer effects of dietary compounds

caffeine, caffeic acid and their combination on oral

squamous cell carcinoma

model

Periyar 27.03.2015

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5. R. Revathi Individual and synergetic

effects of umbelliferone with vitamin-C on N-

Nitrosodiethylamine induced

hepatocellular carcinogenesis- An In vivo and In vitro study

Periyar 26.02.2016

6 N. Karthi

Investigation into the anticancer efficacy of

Pelargonidin on colon carcinogenesis: A molecular

approach

Periyar 06.07.2017

7 P. Mariyappan

Molecular and biochemical approach to the anti-carcinogenic effect of

eriodictyol, a dietary flavonoid in DMH induced colon

carcinogenesis

Periyar 05.03.2018

8 H. Preethi Biochemical and molecular mechanism underlying the

cardio protective role of Eriodictyol in isoproterenol

induced myocardial infarction

Periyar 23.03.2018

9 T. Kalaiyarasu Molecular mechanism underlying the anti- cancer

potential of Orientin in

colorectal cancer models

Periyar 28.09.2018