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2210-6007 21 pages

M10/4/BIOLO/HPM/ENG/TZ1/XX+

Monday 17 May 2010 (afternoon)

BiologyHigHer levelPaPer 1

INSTRUCTIONS TO CANDIDATES

• Do not open this examination paper until instructed to do so.• Answer all the questions.• For each question, choose the answer you consider to be the best and indicate your choice on

the answer sheet provided.

1 hour

© International Baccalaureate Organization 2010

2 2 1 0 6 0 0 7

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1. The lengthsofa sampleof tigercaninesweremeasured. 68%of the lengths fellwithina rangebetween15mmand45mm.Themeanwas30mm.Whatisthestandarddeviationofthissample?

A. 5mm

B. 15mm

C. 7.5mm

D. 30mm

2. Whichofthefollowingarefeaturesofprokaryotesandeukaryotes?

70S ribosomes 80S ribosomes Naked DNA DNA associated with proteins

A. prokaryote eukaryote prokaryote eukaryote

B. eukaryote prokaryote eukaryote prokaryote

C. eukaryote prokaryote prokaryote eukaryote

D. prokaryote eukaryote eukaryote prokaryote

3. Whichstatementispartofthecelltheory?

A. Cellsarecomposedoforganicmolecules.

B. CellshaveDNAastheirgeneticmaterial.

C. Cellshavecytoplasmsurroundedbyamembrane.

D. Cellscomefrompre-existingcells.

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4. Whatrouteisusedtoexportproteinsfromthecell?

A. Golgiapparatus→roughendoplasmicreticulum→plasmamembrane

B. Roughendoplasmicreticulum→Golgiapparatus→plasmamembrane

C. Golgiapparatus→lysosome→roughendoplasmicreticulum

D. Roughendoplasmicreticulum→lysosome→Golgiapparatus

5. Whichofthefollowingtake(s)placeduringeitherinterphaseormitosisinanimalcells?

I. Re-formationofnuclearmembranes II. Pairingofhomologouschromosomes III. DNAreplication

A. Ionly

B. IandIIonly

C. IIandIIIonly

D. IandIIIonly

6. Whichsubstanceinprokaryotescontainssulfur?

A. DNA

B. Phospholipids

C. Proteins

D. Antibiotics

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7. Whichdescribesthesemoleculescorrectly?

I.

II.

I II

A. ribose aminoacid

B. glucose aminoacid

C. ribose fattyacid

D. glucose fattyacid

C O

CH2OH

HC

C C

COH

H

H

OH

H

OH

H

OH

O

C

OH

(CH2)nCH3

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8. WhatsequenceofprocessesiscarriedoutbythestructurelabelledXduringtranslation?

X

UACA U G C C G U A C G A U C

A. Combiningwithanaminoacidandthenbindingtoananticodon

B. Bindingtoananticodonandthencombiningwithanaminoacid

C. Bindingtoacodonandthencombiningwithanaminoacid

D. Combiningwithanaminoacidandthenbindingtoacodon

5′ 3′

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9. Thediagrambelowshowsabiochemicalpathwayinayeastcell.Whichofthefollowingcorrectlyidentifiesacompoundinthediagram?

A. Iisfat.

B. IIispyruvate.

C. IIIislactate.

D. IViscarbondioxide.

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10. Whichofthefollowingfactorsinfluence(s)therateofoxygenproductioninphotosynthesis?

I. Temperature II. Wavelengthoflight III. Numberofmitochondria

A. Ionly

B. IandIIonly

C. IIandIIIonly

D. I,IIandIII

11. Insomepeople,hemoglobinalwayscontainstheaminoacidvalineinplaceofaglutamicacidatonepositionintheprotein.Whatisthecauseofthis?

A. Anerrorintranscriptionofthehemoglobingene

B. AnerrorintranslationofthemRNA

C. Lackofglutamicacidinthediet

D. Abasesubstitutioninthehemoglobingene

12. Whatisasuspectedheterozygousindividualcrossedwithinatestcross?

A. Homozygousdominant

B. Homozygousrecessive

C. Heterozygousdominant

D. Heterozygousrecessive

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13. Whichof the followinggenotypes ispossible in theoffspringof ahomozygousmalewithbloodgroupAandafemalewithbloodgroupB?

A. IAIA

B. IAi

C. ii

D. IBi

14. Whattypeofinheritanceisshowninthispedigreechart?

Key:

Affected

Carrier

A. X-linkeddominant

B. Y-linkeddominant

C. X-linkedrecessive

D. Y-linkedrecessive

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15. Whatisacommunity?

A. Agroupoforganismslivingandinteractinginthesametrophiclevel

B. Agroupofpopulationslivingandinteractinginafoodchain

C. Agroupoforganismsofthesamespecieslivingandinteractinginanecosystem

D. Agroupofpopulationslivingandinteractinginanarea

16. Whataretheunitsofapyramidofenergy?

A. kJmyr

B. kJmyr

C. Jms

D. Jms

17. Populationsizeisinfluencedbycertainfactors. IfI=immigration,E=emigration,N=natality,M=mortalityand(N+M)=(I+E)=0,which

phaseisthispopulationin?

A. Exponentialphase

B. Transitionalphase

C. Plateauphase

D. Growthphase

18. Ananimalhasradialsymmetry,asac-likebodywithonlyoneopeningandtentacleswithstingingstructures.Towhichphylumdoesthisanimalbelong?

A. Annelida

B. Cnidaria

C. Mollusca

D. Porifera

1−

2−

1−

1−

1−

3−

2 1−

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19. Whichofthefollowingareusedasevidenceforevolution?

I. Homologousstructures II. Selectivebreedingofdomesticatedanimals III. Overproductionofoffspring

A. IandIIonly

B. IandIIIonly

C. IIandIIIonly

D. I,IIandIII

20. Whichofthefollowingiscorrectforlipase?

Substrate Source pH optimum

A. triglycerides pancreas pH=8

B. fattyacids smallintestine pH=7

C. triglycerides smallintestine pH=9

D. fattyacids pancreas pH=9

21. Whatpreventsantibioticsfrombeingeffectiveagainstviruses?

A. Viruseshaveahighrateofmutation.

B. ViruseshavenoRNA.

C. Viruseshavenometabolism.

D. Viruseshaveaproteinshellthatprotectsthem.

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22. Thediagrambelowshowsthehumanheart.WhatstructuresareindicatedbythelabelsX,YandZ?

X

Z

Y

[Source:adaptedfromhttp://whyfiles.org/102spareparts/images/heart2.gif]

X Y Z

A. leftatrium aorta semi-lunarvalve

B. leftatrium aorta atrio-ventricularvalve

C. rightatrium pulmonaryartery atrio-ventricularvalve

D. rightatrium pulmonaryartery semi-lunarvalve

23. Whichmusclescontracttocauseairtopassintothelungsthroughthetrachea?

A. Internalintercostalmusclesanddiaphragm

B. Internalintercostalmusclesandabdomenwallmuscles

C. Externalintercostalmusclesanddiaphragm

D. Externalintercostalmusclesandabdomenwallmuscles

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1

2

24. The diagram below shows the changes in membrane potential during an action potential. Whatoccursatthestageslabelled1and2?

Mem

branepotential/mV

+60

+40

0

–40

–60

–100

Actionpotential

Thresholdpotential

Restingpotential

0 1 2 3 4 5 6 7 8Time/msec

1 2

A. Na+ionsdiffusein;insidebecomesmorepositive

K+ionsdiffuseout;insidebecomesmorenegative

B. K+ionsdiffuseout;insidebecomesmorenegative

Na+ionsdiffusein;insidebecomesmorepositive

C. Na+ionsdiffuseout;insidebecomesmorenegative

K+ionsdiffuseout;insidebecomesmorepositive

D. Na+ionsdiffusein;insidebecomesmorepositive

K+ionsdiffusein;insidebecomesmorenegative

25. Whataretherolesoftestosteroneinmales?

A. StimulationofFSHproductionandgrowthinpuberty

B. Pre-nataldevelopmentofgenitaliaanddevelopmentofsecondarysexualcharacteristics

C. Developmentofgenitaliaandpre-natalsecondarysexualcharacteristics

D. StimulationofFSHproductionandpre-nataldevelopmentofsecondarysexualcharacteristics

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26. WhatisthereasonforOkazakifragmentsbeingformedduringDNAreplication?

A. Toenablereplicationofthe3′→5′(lagging)strand

B. ToformthetemplatefortheRNAprimers

C. Toinitiatereplicationonthe5′→3′(leading)strand

D. TohelptheDNAhelicaseunwindingtheDNAhelix

27. Whichiscorrectforthenon-competitiveinhibitionofenzymes?

Inhibitor resembles substrate

Inhibitor binds to active site

A. yes yes

B. yes no

C. no yes

D. no no

28. WhatisremovedduringtheformationofmatureRNAineukaryotes?

A. Exons

B. Introns

C. Codons

D. Nucleosomes

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29. Duringglycolysisahexosesugarisbrokendowntotwopyruvatemolecules. Whatisthecorrectsequenceofstages?

A. Phosphorylation→oxidation→lysis

B. Oxidation→phosphorylation→lysis

C. Phosphorylation→lysis→oxidation

D. Lysis→oxidation→phosphorylation

30. Wherearethelight-dependentandlight-independentreactionstakingplaceinthediagrambelow?

I II

IV III

Light-dependent Light-independent

A. I IV

B. II III

C. III II

D. IV I

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31. Whataredifferencesbetweenmonocotyledonousanddicotyledonousplants?

Monocotyledonous Dicotyledonous

A. parallelvenation;floralorgansinmultiplesof4or5

net-likevenation;floralorgansinmultiplesof3

B. net-likevenation;floralorgansinmultiplesof3

parallelvenation;floralorgansinmultiplesof4or5

C. net-likevenation;floralorgansinmultiplesof4or5

parallelvenation;floralorgansinmultiplesof3

D. parallelvenation;floralorgansinmultiplesof3

net-likevenation;floralorgansinmultiplesof4or5

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32. Thediagrambelowshowspartofthevascularsystemofadicotyledonousplant.Whichprocessisindicatedbythearrows?

[FREEMAN,SCOTT,BIOLOGICALSCIENCE,3rdEdition,copyright2008,p.828.ReprintedbypermissionofPearsonEducation,Inc.,UpperSaddleRiver,NJ]

A. Passivetranslocationinthephloemofsucrosefromthesinktothesource

B. Activetranslocationinthephloemofsucrosefromthesourcetothesink

C. Passivetranslocationinthexylemofsucrosefromthesinktothesource

D. Activetranslocationinthexylemofsucrosefromthesourcetothesink

33. Whatcontrolsthefloweringprocessinlong-dayplants?

A. PfrisconvertedbyredlighttoPrwhichactsasapromoterofflowering.

B. PrisconvertedbyredlighttoPfrwhichactsasaninhibitorofflowering.

C. PrisconvertedbyredlighttoPfrwhichactsasapromoterofflowering.

D. PfrisconvertedbyredlighttoPrwhichactsasaninhibitorofflowering.

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34. Atestcrossresultedintheserecombinants:

tB Tbtb tb

Whichofthefollowingwastheparentaltestcross?

A.TB tb

tb×

tb

B.TB tbtB

×Tb

C.Tb tbtB

×tb

D.TB TB

tb×

tb

35. Whatoccursduringthebloodclottingprocess?

A. Prothrombinisconvertedintothrombinwhichactsonfibrinogen.

B. Prothrombinisconvertedintothrombinwhichactsonfibrin.

C. Fibrinogenisconvertedintofibrinwhichactsonprothrombin.

D. Fibrinogenisconvertedintofibrinwhichactsonthrombin.

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36. WhatisindicatedbythelettersX,YandZ?

X Y Z

A. sarcomere myosinfilaments actinfilaments

B. sarcomere actinfilaments myosinfilaments

C. darkband myosinfilaments actinfilaments

D. darkband actinfilaments myosinfilaments

Z

XY

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37. Thediagrambelowshowssomestagesintheproductionofmonoclonalantibodies.WhatarestagesX,YandZ?

[UsedwiththepermissionofAccessExcellence@theNationalHealthMuseum]

X Y Z

A. injectionofantibody isolationofB-cell fusionbetweenB-cellandtumourcellresultinginplasmacell

B. injectionofantibody isolationofT-cell fusionbetweenT-cellandtumourcellresultinginplasmacell

C. injectionofantigen isolationofT-cell fusionbetweenT-cellandtumourcellresultinginhybridomacell

D. injectionofantigen isolationofB-cell fusionbetweenB-cellandtumourcellresultinginhybridomacell

X

Y

Z

Tumourcells

Tissueculture

Monoclonalantibodiesisolatedforcultivation

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38. Inthediagramofthenephronbelow,whatstructuresareindicatedbythelettersYandZ?

[Source:adaptedfromhttp://ex.susd.org/sjones/SGHL12007files/image005.jpg]

Y Z

A. glomerulus collectingduct

B. Bowman’scapsule collectingduct

C. Bowman’scapsule distalconvolutedtubule

D. glomerulus distalconvolutedtubule

Y

Z

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39. Whataretherolesofthefollowingstructuresintheproductionofsemen?

Epididymis Seminal vesicle Prostate gland

A. production of a fluidcontaining alkalineminerals

productionoffructose maturationofsperm

B. maturationofsperm production of a fluidcontainingcitricacid

productionoffructose

C. maturationofsperm productionoffructose production of a fluidcontaining alkalineminerals

D. production of a fluidcontaining alkalineminerals

maturation of sperm productionoffructose

40. WhatistheroleofHCGinearlypregnancy?

A. Itpreventsthedegenerationofthecorpusluteum.

B. Itinitiatesthedevelopmentoftheuteruslining.

C. Itinhibitstheproductionofestrogen.

D. Itstimulatesthedegenerationofthecorpusluteum.

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