monthly study slides tumors of the testesintra-abdominal gonads which grossly resembled testes were...

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* * * * * * * * * * * * * * * * * * ic * * * * * * * * * * * CALIFORNIA TUMOR TISSUE REGISTRY LOS 1\NGEI.ES COllN'l'Y - UNIVERSITY OF SOUTHERN CALIFORNIA MEDICAL CENTER PROTOCOL For MONTHLY STUDY SLIDES MAY 1974 TUMORS OF THE TESTES ic * * * * * * * * * * * * * ic * * * * * -/( * * * * * * * * *

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Page 1: MONTHLY STUDY SLIDES TUMORS OF THE TESTESintra-abdominal gonads which grossly resembled testes were biopsied. Following consultation, it was decided that additional surgery be performed

* * * * * * * * * * * * * * * * * * ic * * * * * * * * * * *

CALIFORNIA TUMOR TISSUE REGISTRY

LOS 1\NGEI.ES COllN'l'Y - UNIVERSITY OF SOUTHERN CALIFORNIA MEDICAL CENTER

PROTOCOL

For

MONTHLY STUDY SLIDES

MAY 1974

TUMORS OF THE TESTES

ic * * * * * * * * * * * * * ic * * * * * -/( * * * * * * * * *

Page 2: MONTHLY STUDY SLIDES TUMORS OF THE TESTESintra-abdominal gonads which grossly resembled testes were biopsied. Following consultation, it was decided that additional surgery be performed

NAME: L. J. G.

AGE: 17 SEX: Female RACE: Unknown

CONTRIBUTOR: Reuben Straus, M.D. St. Joseph Hospital Burbank, California

TISSUE FROM: Intra-abdominal gonads

CLINICAL ABSTRACT:

MAY 1974 - CASE NO. 1

ACCESSION NO. 14446

OUTSIDE NO. 1451-64

This 17 year old female first sought medical attention at the age of 14 for bilateral inguinal hernias which had been present since infancy. At puberty, breast development and pubic hair growth were adequate al­though menstruation was absent. Body contours were distinctly feminine. The vagina was small. Buccal smears revealed Barr bodies in only 2% of cells and a 24 hour urine contained 6 micrograms estrogen (prepubertal normal level) and normal urinary 17 ketogenic steroids. During the herniorrhaphy the uterus and fallopian tubes were noted to be absent. The intra-abdominal gonads which grossly resembled testes were biopsied. Following consultation, it was decided that additional surgery be performed.

SURGERY: (March 1964)

Bilateral gonadectomy and incidental appendectomy were performed,

GROSS PATHOLOGY:

The surface of both gonads were smooth, glistening and pearly grey, The parenchyma consisted of tan tissue resembling testicular tissue,

FOLLOW-UP:

In the years following these procedures, the patient was twice married and divorced.

Page 3: MONTHLY STUDY SLIDES TUMORS OF THE TESTESintra-abdominal gonads which grossly resembled testes were biopsied. Following consultation, it was decided that additional surgery be performed

NAME: H. A. "MAY ·1974 - CASE NO. 2

AGE: 81 SEX: Male RACE: Caucasian ACCESSION NO. 17327

CONTRIBUTOR: E. R. Jennings, M.D. OUTSIDE NO. 5726-66 Memorial Hospital of Long Beach Long Beach, California

TISSUE FROM: Testis

CLINICAL ABSTRACT:

This 81 year old Caucasian male presented with a three week history of painless swelling of the left testicle.

Physical Examination: The mass in the left scrotum was semi-soft and slightly irregular. The right testis was normal and no enlarged inguinal lymph nodes were palpated. Bilateral herniorrhaphy scars were also noted.

Laboratory: A chest radiograph and pyelogram were within normal limits.

SURGERY:

A left orchiectomy was performed.

GROSS PATHOLOGY:

The testis and epididymis were both yellow-tan and uniformly enlarged, measuring up to 3.5 em. and 1.5 em. respectively. The spermatic cor d was grossly normal.

FOLLOW-UP:

The only information available is that the patient expired 5 months later from peritoni tis following surgery for an ulcer.

Page 4: MONTHLY STUDY SLIDES TUMORS OF THE TESTESintra-abdominal gonads which grossly resembled testes were biopsied. Following consultation, it was decided that additional surgery be performed

NAME: M. R. MAY 1974 - CASE NO. 4

AGE: 40 SEX: Male RACE: Caucasian ACCESSION NO. 18679

CONTRIBUTOR: J. Reynolds, M.D •. · OUTSIDE NO. 2541-70 Memorial Hospital of Long Beach Long Beach, California

TISSUE FROM: Testis

CLINICAL ABSTRACT:

This 40 year old Caucasian male presented with a swollen left testis of six months' duration. The lesion o~aured 7 em. in d!~~t€r, did not transilluminate and was not painful or tender.

SURGERY: (April 15, 1970)

A left radical orchiectomy was performed. An abdominal exploration revealed no enlarged lymph nodes.

GROSS PATHOLOGY:

The testis and attachedSl'JM'm.atic cord weighed 145 grams. The testicular capsule was smooth and glistening. The cut surface revealed the parenchyma to be entirely replaced by a uniform bulging soft tan lesion containing small focal areas of necrosis. No cystic areas were seen.

FOLLOW-UP:

The patient r~ceived 2200 r<~ds to the p<lra-oortic, left iliac and lef t supraclavicular nodes. As of April 4, 1973 the patient is alive and well with no evidence of recurrence.

Page 5: MONTHLY STUDY SLIDES TUMORS OF THE TESTESintra-abdominal gonads which grossly resembled testes were biopsied. Following consultation, it was decided that additional surgery be performed

NAME: J. M.

AGE: 39 SEX: Male RACE: Caucasian

CONTRIBUTOR: R. L. Lesonsky. M.D. LAc~usc Medical Center Los Angeles, California

TIS SUE FROM: Testis

CLINICAL ABSTRACT:

MAY 1974 - CASE NO. 5

ACCESSION NO. 15514

OUTSIDE NO. 67-2057

This 39 year old Caucasian male presented with a right scrotal mass of one year's duration.

Physical Examination: The mass measured 8 x 5 em. and did not trans­illuminate. Inguinal lymph nodes were not enlarged and the left testis was normal .

Laboratory: An immunoassay for chorionic gonadotropin was reported as "none detectable".

Radiograph: A metastatic bone survey revealed no abnormalities.

SURGERY: (February 17, 1967)

A right orchiectomy and retroperitoneal lymph node dissection were performed.

GROSS PAnlOLOGY:

The tumor 't-tas well encapsulated and measured 8.5 x 4.5 x 4.0 em. On cut section it was straw colored, soft, hemorrhagic and contained small grey cysts.

Gross and micx:os<> ot ):lc exami.nA.tion of the l ymph nodes di d not reveal any me tastatic tumor.

FOLLOW-UP:

As of Mt~rch 1974 the patient is alive and "not feeling .well".

Page 6: MONTHLY STUDY SLIDES TUMORS OF THE TESTESintra-abdominal gonads which grossly resembled testes were biopsied. Following consultation, it was decided that additional surgery be performed

NAME: W. P.

AGE: 12 SEX: Male RACE: Caucasian

CONTRIBUTOR: Paul Thompson, M.D. St. Luke Hospital Pasadena, California

TISSUE FROM: Testis

CLINICAL ABSTRACT:

MAY 1974 - CASE NO. 6 & 6A

ACCESSION NO. 19786

OUTSIDE NO. SL-948-72 A 2607

This 12 year old Caucasian male presented with a right scrotal mass.

SURGERY: (May 2, 1972)

A right orchiectomy was performed.

GROSS PATHOLOGY: (SL-948-72)

The tumor consisted of pale, gray-white, firm glistening tissue which measured 8 em. x 6 em., and did not involve a normal appearing testis, which measured 3.5 x 2.5 em.

GROSS PA niOLOGY: (A 2607)

The spleen weighed 110 grams. The capsule was completely surrounded by tumor. The parenchyma showed the usual fq1licular and trabecular pattern with no focal lesions.

The pancreas was encased by tumor, but no tumor nodules were present within the parenchyma. The duct was patent and entered the duodenum at the ampulla.

FOLLOW-UP:

The patient died in November 1973 with metastatic tumor involving the peritoneal, pleural and pericardia! surfaces. left kidneys, the pancreas, the spleen, the adrenals and the encased by tumor with only occasional sites of penetration.

massively The right and colon were all

No residual tumor was present in the right scrotum. The left t estis was free of tumor.

Page 7: MONTHLY STUDY SLIDES TUMORS OF THE TESTESintra-abdominal gonads which grossly resembled testes were biopsied. Following consultation, it was decided that additional surgery be performed

NAME: H. W ..

AGE: 52 SEX; Male .RAC..E: Caucasian

CONTRIBUTOR: S. H. Choy, M.D. V. A. Hospital San Francisco, California

TISSUE FROM: Testis

CLINICAL ABSTRACT:

MAY 1974 - CASE NO. 7

ACCESSION NO. 17460

OUTSIDE NO. S-1366-67

This 52 y.o. Caucasian male first noted swelling of his left testis nine months before admission. It was originally diagnosed as a hydrocele. A few months prior to resection, however, the lesion began to grow at an alarming rate.

SURGERY: (July 17, 1967)

A left orchiectomy was performed.

GROSS PATHOLOGY:

The tumor weighed 3000 grams and was the size and shape of a football. The tunica albuginea covered the mass except where it invaded the scrotal sac. On cut section it was grey-white, homogeneous and cerebroid with large areas of yellow necrosis.

FOLLOW-UP:

The patient died four months after surgery. At post mortem examination metastatic tumor was found in the lungs, liver, bone, neck and retroperi­toneum.

Page 8: MONTHLY STUDY SLIDES TUMORS OF THE TESTESintra-abdominal gonads which grossly resembled testes were biopsied. Following consultation, it was decided that additional surgery be performed

NAME: D. W.

AGE: 77 SEX: Male RACE: Caucasian

CONTRIBUTOR: J. R. Phillips, M.D. St. Agnes Hospital Fresno, California

TISSUE FROM: Testicle

CLINICAL ABSTRACT:

MAY 1974 - CASE NO. 8

ACCESSION NO. 18882

OUTSIDE NO. S-70-6113

This 77 year old Caucasian male first noted left testicular swelling four years prior to admission. It was diagnosed as a hydrocele and drained. Gradually it slowly refilled with fluid and was re-drained of 16 ounces of fluid three days prior to admission. This time, however, the "hydrocele" refilled rapidly. In addition his physician had diagnosed a left inguinal hernia which extended into the left scrotal sac. Recently he began to develop tender breasts.

Past History: years previously.

A diagnosis of prostatic carcinoma had been made two The patient received Stilbesterol . therapy.

SURGERY: (October 29, 1970)

A left inguinal herniorrhaphy and bilateral orchiectomies were per­formed.

GROSS PATHOLOGY:

The left testis consisted of a 12 em., hemorrhagic, empty sac-like structure. Testicular tissue was evident in one portion of the cyst wall. The proximal spermatic cord was unremarkable. The right testis was atrophic.

FOLLOW-UP:

The patient is alive and well at the present time with some prostatism but no other complaints.

Page 9: MONTHLY STUDY SLIDES TUMORS OF THE TESTESintra-abdominal gonads which grossly resembled testes were biopsied. Following consultation, it was decided that additional surgery be performed

)

NAME: W. J.

AGE: 26 SEX: Male RACE: Caucasian

CONTRIBUTOR: Steven Scholtz, M.D. LAC-USC Medical Center Los Angeles, California

TISSUE FROM: Testis

CLINICAL ABSTRACT:

MAY 1974 - CASE NO. 9

ACCESSION NO. 15001

OUTSIDE NO. 66-7651

This 26 year old Caucasian male presented with headaches and difficulty maintaining his balance.

Physical Examination: · The right testis was stony· hard and enlarged to three ttmes its normal size.

SURGERY: (June 2, 1966)

A right orchiectomy was performed.

GROSS PATHOLOGY:

The testis measured 7.0 x 4.5 x 4.0 em. and weighed 83 grams. It was completely replaced by tumor which had a mottled appearance. There were foci of brown-red tissue and dark-red tissue separated by light tan tra• beculae.

FOLL0\-7-UP:

The patient died one week following surgery. Metastases were present in the brain, lungs, liver and kidneys. No laboratory studies for chorionic gonadotropin were performed.

Page 10: MONTHLY STUDY SLIDES TUMORS OF THE TESTESintra-abdominal gonads which grossly resembled testes were biopsied. Following consultation, it was decided that additional surgery be performed

NAME: K. F.

AGE: 25 SEX: Male RACE: Unknown

CONTRIBUTOR: A- E. Laraway, M.D. Glendale Community Hospital Glendale, California

TISSUE FROM: Testis

CLINICAL ABSTRACT:

MAY 1974 - CASE NO. 10

ACCESSION NO. 19377

OUTSIDE NO. G-1239-71

This 25 year old male presented with a one week history of left testicular swelling. There was no history of trauma.

Physical Examination: The right testis was normal. The left testis was hard, nodular and non-tender.

SURGERY: (June 16, 1971)

A left orchiectomy and inguinal dissection were performed.

GROSS PATHOLOGY:

The testis weighed 58.0 grams and measured 6.0 x 4.5 x 3.0 em. A solid, lobulated, grey and pink tumor occupied the upper two-thirds of the testis. Two SUnilar appearing lesions, measuring up to 1.2 em. in dimension, were present in the lower one-third of the testis.

Gross and microscopic examination of the lymph nodes did not reveal any metastatic tumor.

FOLLOW-UP:

In March 1972· the patient also undexwent a left retroperitoneal and deep inguinal lymph node dissection. He is alive and without evidence of any r ecurrent tumor at the present time.

Page 11: MONTHLY STUDY SLIDES TUMORS OF THE TESTESintra-abdominal gonads which grossly resembled testes were biopsied. Following consultation, it was decided that additional surgery be performed

)

NAME: M. W.

AGE: 17 SEX: Na1e RACE: Caucasian

CONTRlEUTOR: Shinichi Hamashige, M.D. St. Jude Hospital Fullerton, California

TISSUE FR011: Testis

CLINICAL ABSTRACT:

MAY 1974 - CASE NO. 11

ACCESSION NO. 18926

OUTSIDE NO. 6318-70

This 17 year old Caucasian male presented with left testicular pain of apparently sudden onset.

SURGERY: (December 4, 1970)

The left testis and 9 em. of spermatic cord ~;ere resected.

GROSS PATHOLOGY:

The testis measured 5 em. in diameter and 8 em. in length. It weighed 110 grams. The capsule was smooth and shiny. On cut section, the testis was completely replaced by light tan tumor which had a mucoid appearance. Irregular light yellowish dry areas were also noted.

FOLLOitl·UP:

As of January 25, 1974 the patient was in good health. Physical examina­tion and radiographs at that time were negative for any abnormalities.

Page 12: MONTHLY STUDY SLIDES TUMORS OF THE TESTESintra-abdominal gonads which grossly resembled testes were biopsied. Following consultation, it was decided that additional surgery be performed

NAME: D. D.

AGE: 10 SEX: Male RACE: Caucasian

CONTRIBUTOR: Ernest Tucker, M.D. El Cajon Valley Hospital El Cajon, California

TISSUE FROM: Testis

CLINICAL ABSTRACT:

MAY 1974 - CASE NO. 12

ACCESSION NO. 18810

OUTSIDE NO. ECV 70-2121

This 10 year old boy presented with an enlarged left testis of two months duration. There was no history of local injury or discomfort. Both testes had been noted to be in the scrotum at birth.

Physical Examination: A firm mass "about the size of a navel orange" was present in the left scrotum. The right testis l~as normal. The prostate gland was unremarkable. No other abnormalities were noted. It was not ' possible to differentiate the epididymis from the mass.

SURGERY:

The left testis and a portion of spermatic cord ·were resected.

GROSS PATHOLOGY:

The testis weighed 180 grams and measured 7.0 em. in greatest dimension. In the region of the epididymis there was focal residual testicular parenchyma. n1e remainder of the testis consisted of soft homogeneous grey-tan tissue which had a fish flesh appearance.

FOLLOW-UP:

Socn after the ~urgery the patient was referred to the Memorial Sloan-Kettering Cancer Center where, on September 30, 1970~a left hemiscrotec­tomy and a left superficial inguinal, para-aortic and pelvic lymph node dissection were performed. Metastatic tumor was present in one lymph node (t here were over 100 lymph nodes identified in the specimen). Consequently the patient received both radiotherapy and chemotherapy (Cytoxan and Vincristine). In November 1970 an abdominal mass was noticed. At laparotomy a large left-sided retroperitoneal tumor was found obstructing the left · ureter. The mass also involved loops of small blm~el and the mesentery, and was not resectable. No further information is available.

Page 13: MONTHLY STUDY SLIDES TUMORS OF THE TESTESintra-abdominal gonads which grossly resembled testes were biopsied. Following consultation, it was decided that additional surgery be performed

)

STUDY GROUP CASES

For

~1 1974

CASE NO. 1 ACC. NO. 14446 CONTRIBUTOR: Reuben Straus, M.D.

LOS ANGELES: Testicular feminization syndrome - 15

CENTRAL VALLEY: Immature abdominal testes in an intersex patient, with . conspicuous interstitial cells - 11

OAKLAND: Testicular feminization - 13

WEST LOS ANGELES;. Pseudo-hermaphroditism with testicular feminization - 8

SAN FRANCISCO: Testicular feminization - 14

SAN BERNARDINO: Testicular feminization syndrome - 12

~: Testis with tubular atrophy and interstitial cell hyperplasia - 2

ORANGE: Cryptorchid testes (testicular feminization syndrome) - 4

SACRANENTO: Testicular tissue - 6

ARGENITINA: Prepubertal testis, intra-abdominal (incomplete male pseudo­hermaphrodite)

MINNESOTA; Male pseudo-hermaphrodite - 1

SEATTLE: Testicular feminization (androgen insensitivity) - 11

FILE DI/.GNOSIS:

Testicular feminization syndrome 1869-4648

REFERENCE:

Marshall, Harold K. and Harder, Herbert I.: Testicular Feminizing Syndrome in Male 'Pseudohe-rmaphrooit~. Report of two cas~s in identical twins. Obst. Gyn. Vol. 12, No. 3: 284-293. September 1958.

Page 14: MONTHLY STUDY SLIDES TUMORS OF THE TESTESintra-abdominal gonads which grossly resembled testes were biopsied. Following consultation, it was decided that additional surgery be performed

MAY 1974

CASE NO. 2 ACC. NO. 17327 CONTRIBUTOR: E. R. Jennings, M.D.

LOS ANGELES: Histiocytic sarcoma (reticulum cell sarcoma) - 15

CENTRAL VALLEY: Anaplastic seminoma - 6; interstitial cell tumor, malignant - 2; perhaps lymphoma - 1

embryonal carcinoma - 2; anaplastic undifferentiated metastatic tumor,

OAKLAND: Anaplastic seminoma - 6; histiocytic lymphoma - 5; spermatocytic seminoma - 1; germinal cell tumor - 1

WEST LOS ANGELES: Malignant lymphoma, histiocytic type - 6; anaplastic seminoma - 2

SAN FRANCISCO: Seminoma, anaplastic - 7; histiocytic lymphoma - 7

SAN BERNARDINO: Embryonal carcinoma - 5; anaplastic seminoma- 3; histio­cytic lymphoma - 11

QH!Q: Seminoma with atypical features - 2

ORANGE: Histiocytic lymphoma (reticulum cell sarcoma), testis- 4

SACRAMENTO: Seminoma (anaplastic type) - 6

ARGENTINA: Seminoma, anaplastic

MINNESOTA: Malignant lymphoma, reticulum cell type - 1

SEATTLE: Anaplastic seminoma - 7; histiocytic tumor - 2; spermatocytic seminoma - 1; typical seminoma - 1

FILE DIAGNOSIS:

Malignant lymphoma, histiocytic type 1869-9643

Page 15: MONTHLY STUDY SLIDES TUMORS OF THE TESTESintra-abdominal gonads which grossly resembled testes were biopsied. Following consultation, it was decided that additional surgery be performed

MAY 1974

CASE NO. 4 ACC. NO. 18679 CONTRIBUTOR: J. Re7Dolds, M.D.

LOS ANGELES: Seminoma, NOS - 15

CENTRAL VALLEY: Seminoma - 11

OAKLAND: Seminoma - 11; anaplastic seminoma - 2

'WEST LOS ANGELES: Seminoma - 8

SAN FRANCISCO: Seminoma - 17

SAN BERNARDINO: Seminoma ... 9

~: Seminoma - 2

ORANGE: Seminoma, testis - b,.

SACRAMENTO: Seminoma, typical - 6

ARGENTINA: Seminoma, typical

MINNESOTA: Seminoma - 1

SEAT1tE: Typical seminoma ... 11

FILE DIAGNOSIS: ·.

Seminoma, testis 1869-9063

Page 16: MONTHLY STUDY SLIDES TUMORS OF THE TESTESintra-abdominal gonads which grossly resembled testes were biopsied. Following consultation, it was decided that additional surgery be performed

MAY 1974

CASE NO. 5 ACC. NO. 15514 CONTRIBUTOR: R. L. Lesonsky, M.D.

LOS ANGELES: Spermatocytic seminoma - 15

CENTRAL VALLEY: Hodgkins' - 1;

Anaplastic seminoma - 5; interstitial cell tumor - 2; undifferentiated carcinoma - 1

OAKLAND: Spermatocytic seminoma - 13

WEST LOS ANGELES: Spermatocytic seminoma - 8

SAN FRANCISCO: Spermatocytic seminoma - 14; seminoma, anaplastic - 3

SAN BERNARDINO: Seminoma - 1; spermatocytic seminoma - 6; anaplastic seminoma - 2

Qtl!Q: Seminoma - 2

ORANGE: Spermatocytic seminoma, testis - 4

SACRAMENTO: Seminoma - 6

ARGENTINA: Seminoma (spermatocytic type)

MINNESOTA: Spermatocytic seminoma - 1

SEATTLE: SpeTmatocytic seminoma - 10; rhabdomyosarcoma - 1

CONSULTATION:

Dr. G. Barry Pierce agrees with this diagnosis.

FILE DIAGNOSIS:

Spermatocytic seminoma, testis · 1869-9063

Page 17: MONTHLY STUDY SLIDES TUMORS OF THE TESTESintra-abdominal gonads which grossly resembled testes were biopsied. Following consultation, it was decided that additional surgery be performed

MAY 1974

CASE NO. 6 ACC. NO. 19786 CONTRIBUTOR; Paul Thompsom, M.D.

LOS ANGELES: Rhabdomyosarcoma - 15

CENTRAL VALLEY: Sarcoma botryoides - 11

OAKLAND: Rhabdomyosarcoma - 13

WEST LOS ANGELES: Rhabdomyosarcoma - 8

SAN FRANCISCO: Rhabdomyosarcoma - 17

SAN BERNARDINO: Rhabdomyosarcoma - 9

Qg!Q: Myosarcoma, probable rhabdomyosarcoma - 2

ORANGE: Rhabdomyosarcoma, spermatic cord - 4

SACRAMENTO: Rhabdomyosarcoma - 6

ARGENTINA: Myosarcoma, multiple sites

MINNESOTA: Juvenile rhabdomyosarcoma - 1

SEATTLE: Rhabdomyosarcoma - 10; malignant mesenchymoma - 1

FILE DIAGNOSIS:

Rhabdomyosarcoma, spermatic cord 1871-8903

Page 18: MONTHLY STUDY SLIDES TUMORS OF THE TESTESintra-abdominal gonads which grossly resembled testes were biopsied. Following consultation, it was decided that additional surgery be performed

MAY 1974

CASE NO. 6A ACC. NO. 19786 CONTRIBUTOR: Paul Thompson, M.D.

LOS ANGELES: Rhabdomyosarcoma - 15

CENTRAL VALLEY: Rhabdomyosarcoma - 11

OAKLAND: Rhabdomyosarcoma - 13

WEST LOS ANGELES: Rhabdomyosarcoma - 8

SAN FRANCISCO: Rhabdomyosarcoma - 17

SAN BERNARDINO: Rhabdomyosarcoma - 9

~: Rhabdomyosarcoma - 2

ORANGE: Metastatic rhabdomyosarcoma, spleen - 4

SACRAMENTO: Rhabdomyosarcoma - 6

ARGENTINA: Myosarcoma, multiple sites

MINNESOTA·: Juvenile rhabdomyosarcoma - 1

SEATTLE: Rhabdomyosarcoma - 10; malignant mesenchymoma - 1

FILE DIAGNOSIS :

Metastatic rhabdomyosarcoma, spleen Metastatic rhabdomyosarcoma, pancreas

1692-8903 1579-8903

Page 19: MONTHLY STUDY SLIDES TUMORS OF THE TESTESintra-abdominal gonads which grossly resembled testes were biopsied. Following consultation, it was decided that additional surgery be performed

MAY 1974

CASE NO. 7 ACC. NO. 17460 CONTRIBUTOR: S. H. Choy, M. D.

LOS ANGELES: Yolk sac carcinoma - 15

CENTRAL VALLEY: Embryonal carcinoma - 11

OAKLAND: Embryonal carcinoma - 7; endodermal sinus tumor - 6

t.mST LOS ANGELES: Endodermal sinus tumor - 7; anaplastic carcinoma - 1

SAN FRANCISCO: Yolk sac tumor (carcinoma) - 13; embryonal carcinoma - 4

SAN BERNARDINO: Endodermal sinus tumor - 6; reticular embryonal carcinoma - 3

Qtl!Q: Embryonal carcinoma - 2

ORANGE: Endodermal sinus tumor of Teilum (yolk sac carcinoma},testis - 4

SACRAMENTO: Embryonal carcinoma, epithelial type - 6

ARGENTINA : Embryonal carcinoma, infantile type

MINNESOTA: Embryonal carcinoma - 1

SEATTLE: Embryonal carcinoma, infantile type - 11

FILE DIAGNOSIS:

xolk s~~ carcinoma (embryonal carcinoma, juvenile type} (endodermal sinus tumor}, testis 1869-9073

REFERENCE:

Pierce , G. Barry, Bullock, Weldon K., and Huntington Jr. , Robert W.: Yolk Sac Tumors of the Testis. Cancer 25: 644-658, March 1970 No. 3

Page 20: MONTHLY STUDY SLIDES TUMORS OF THE TESTESintra-abdominal gonads which grossly resembled testes were biopsied. Following consultation, it was decided that additional surgery be performed

MAY 1974

CASE NO. 8 ACC. NO. 18882 CONTRIBUTOR: J. R, Phillips, M.D.

LOS ANGELES: Metastatic carcinoma from prostate - 3; papillary mesothelioma­tO; adenocarcinoma~ primary site unltnown - 2

CENTRAL VALLEY: Papillary adenocarcinoma of rete testis - 8; malignant mesothelioma - 3

OAKLAND: Papillary adenocarcinoma of rete testis - 9; metastatic adeno• carcinoma - 3; carcinosarcoma - 1

viEST LOS ANGELES : epididymis - 1;

Malignant mesothelioma - 6; papillary cystadenoma of papillary adenocarcinoma of rete testis - 1

SAN FRANCISCO: Papillary adenocarcinoma of epididymis - 12; endometrial carcinoma of prostatic utricle - 3; malignant mesothelium - 1

SAN BERNARDINO: Papillary carcinoma of the rete testis - 8; mesothelioma - 1; (Special Tumors of Ovary and Testis~ G. Teilum~ page 406; 1971, Munksgaard Publisher)

OHIO: Mesothelioma - 2

ORANGE: Papillary adenocarcinoma, rete testis - 4

SACRAMENTO: Mesothelioma - 6

ARGENTINA: Embryonal carcinoma (suspected teratocarcinoma with embryonal carcinoma, but did not find cartilage, skin, etc.)

MINNESOTA: Mesothelioma - ·1

SEATTLE: Papillary adenocarcinoma of the rete testis - 10; mesothelioma - 1

FILE DIAGNOSIS:

Mesothelioma, testis X-File: Papillary adenocarcinoma, rete testis

1869-9051 1869-8053

Page 21: MONTHLY STUDY SLIDES TUMORS OF THE TESTESintra-abdominal gonads which grossly resembled testes were biopsied. Following consultation, it was decided that additional surgery be performed

MAY 1974

CASE NO. 9 ACC. NO. 15001 CONTRIBUTOR: Steven Scholtz, M.D.

LOS ANGELES: Choriocarcinoma - 15

CENTRAL VALLEY: Testicular choriocarcinoma - 11

OAKLAND: Choriocarcinoma - 13

WEST LOS ANGELES: Choriocarcinoma - 8

SAN FRANCISCO: Choriocarcinoma - 17

SAN BERNARDINO: Choriocarcinoma - 9

OHIO: Choriocarcinoma - 2

ORANGE: Choriocarcinoma, testis - 4

SACRAMENTO: Choriocarcinoma - 6

ARGENTINA: Choriocarcinoma

MINNESOTA: Choriocarcinoma - 1

SEATTLE: Choriocarcinoma - 11

FILE DIAGNOSIS :

Choriocarcinoma, testis 1869-9103

Page 22: MONTHLY STUDY SLIDES TUMORS OF THE TESTESintra-abdominal gonads which grossly resembled testes were biopsied. Following consultation, it was decided that additional surgery be performed

)

MAY 1974

CASE NO. 10 ACC. NO~ 19377 CONTRIBUTOR: A. E. Laraway, M.D.

LOS ANGELES: Teratoma, adult type - 15

CENTRAL VALLEY: Teratoma, largely differentiated but with primitive elements - 11

OAKLAND: Mature teratoma - 13

WEST LOS ANGELES: Malignant teratoma, intermediate A - 4; teratoma - 3; immature teratoma - 1

SAN FRANCISCO: Teratoma, adult type - 17

SAN BERNARDINO: Adult teratoma with malignant foci - 9

Q!!IQ.: Teratoma - 2

ORANGE: Mature teratoma, testis - 4 :

SACRAMENTO: Adult teratoma - 6

ARGENTINA: Terat~ma, benign (dermoi6 cyst)

MINNESOTA: Teratoma, mature - 1

SE~TTLE: Teratoma • 11

FILE DIAGNOSIS :.

Teratoma, adult type, testis 1869-9080

Page 23: MONTHLY STUDY SLIDES TUMORS OF THE TESTESintra-abdominal gonads which grossly resembled testes were biopsied. Following consultation, it was decided that additional surgery be performed

MAY 1974

CASE NO. 11 ACC. NO. 18926 CONTRIBUTOR: Shinichi Hamashige, M.D.

LOS ANGELES: Immature teratoma with embryonal carcinoma (teratocarcinoma) - 15

CENTRAL VALLEY: Teratocarcinoma - 11

OAKLAND: Teratoma with embryonal cell carcinoma - 13

WEST LOS ANGELES: Teratocarcinoma - 8

SAN FRANCISCO: Teratocarcinoma with embryonal carcinoma - 17

SAN BERNARDINO: Teratoma with embryonal carcinoma - 9

~: Embryonal carcinoma in teratoma - 2

ORANGE: Teratocarcinoma, testis • 4

SACRAMENTO: Embryonal carcinoma with teratoma - 3; teratocarcinoma - 3

ARGENTINA: Teratocarcinoma (with embryonal carcinoma)

MINNESOTA: Teratoma with embryonal carcinoma - 1

SEATTLE: Teratocarcinoma - 11

FILE DIAGNOSIS:

Immature teratoma with embryonal carcinoma, (teratocarcinoma), testis 1869-9083

Page 24: MONTHLY STUDY SLIDES TUMORS OF THE TESTESintra-abdominal gonads which grossly resembled testes were biopsied. Following consultation, it was decided that additional surgery be performed

)

:t-IAY 1974

CASE NO. 12 ACC. NO. 18810 CONTRIBUTOR: Ernest Tucker, M.D.

LOS ANGELES: Embryonal rhabdomyosarcoma - 15

CENTRAL VALLEY: Malignant lymphoma - 4; stromal sarcoma - three; rhabdo­myosarcoma - 3

OAKLAND: Rhabdomyosarcoma - 13

WEST LOS ANGELES: Rhabdomyosarcoma - 8

SAN FRANCISCO: Embryonal rhabdomyosarcoma - 17

SAN BERNARDINO: Embryonal rhabdomyosarcoma - 8; gonadal stromal tumor - 1

OHIO: Poorly differentiated sarcoma, favor malignant schwannoma ~ 2

ORANGE: Embryonal rhabdomyosarcoma - 4

SACR}~NTO: Rhabdomyosarcoma (juvenile) - 5; lymphoma, stem cell type - 1

ARGENTINA: Embryonal rhabdomyosarcoma

MINNESOTA: Juvenile rhabdomyosarcoma - 1

SEATTLE: Undifferentiated carcinoma - 5; small cell sarcoma - 6

FILE DI!l.GNOSIS~

Embryonal rhabdomyosarcoma, testis 1869-8913