multifractal analysis of intracranial eeg in epilepticus rats - springer

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23/12/2014 Multifractal Analysis of Intracranial EEG in Epilepticus Rats Springer http://link.springer.com/chapter/10.1007/9783642249556_42 1/5 Look Inside Get Access Find out how to access previewonly content Neural Information Processing Lecture Notes in Computer Science Volume 7062, 2011, pp 345351 Multifractal Analysis of Intracranial EEG in Epilepticus Rats Abstract Networks of living neurons exhibit diverse patterns of activity, which are always operating far from equilibrium in the mammalian central nervous system. In this study, a blocker of glutamate transporter was employed to detect if nonlinear interactions changed when extra glutamate acted as a potent neurotoxin to neural activity in hippocampus of epileptic Wistar rats. A hypothesis was made that a decrease of complexity of information could be occurred by accumulation of glutamate in hippocampus. An investigation was performed to measure intracranial EEG, which were obtained from two parts of brain in three rat’s groups, by using multifractal detrended fluctuation analysis. The results demonstrate that the change of nonlinear interactions in neural network can be clearly detected by multifractal analysis. Moreover, small fluctuation in activity of network exhibited a decrease in multifractal behavior, suggested that the complexity of information transmitting and storing in brain network was weakened by glutamate accumulation. Article Metrics Citations

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  • 23/12/2014 MultifractalAnalysisofIntracranialEEGinEpilepticusRatsSpringer

    http://link.springer.com/chapter/10.1007/9783642249556_42 1/5

    LookInsideGetAccessFindouthowtoaccesspreviewonlycontentNeuralInformationProcessingLectureNotesinComputerScienceVolume7062,2011,pp345351

    MultifractalAnalysisofIntracranialEEGinEpilepticusRatsAbstractNetworksoflivingneuronsexhibitdiversepatternsofactivity,whicharealwaysoperatingfarfromequilibriuminthemammaliancentralnervoussystem.Inthisstudy,ablockerofglutamatetransporterwasemployedtodetectifnonlinearinteractionschangedwhenextraglutamateactedasapotentneurotoxintoneuralactivityinhippocampusofepilepticWistarrats.Ahypothesiswasmadethatadecreaseofcomplexityofinformationcouldbeoccurredbyaccumulationofglutamateinhippocampus.AninvestigationwasperformedtomeasureintracranialEEG,whichwereobtainedfromtwopartsofbraininthreeratsgroups,byusingmultifractaldetrendedfluctuationanalysis.Theresultsdemonstratethatthechangeofnonlinearinteractionsinneuralnetworkcanbeclearlydetectedbymultifractalanalysis.Moreover,smallfluctuationinactivityofnetworkexhibitedadecreaseinmultifractalbehavior,suggestedthatthecomplexityofinformationtransmittingandstoringinbrainnetworkwasweakenedbyglutamateaccumulation.

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    References(8)

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    AboutthisChapter

    TitleMultifractalAnalysisofIntracranialEEGinEpilepticusRats

    BookTitleNeuralInformationProcessing

    BookSubtitle18thInternationalConference,ICONIP2011,Shanghai,China,November1317,2011,

  • 23/12/2014 MultifractalAnalysisofIntracranialEEGinEpilepticusRatsSpringer

    http://link.springer.com/chapter/10.1007/9783642249556_42 3/5

    Proceedings,PartIPages

    pp345351Copyright

    2011DOI

    10.1007/9783642249556_42PrintISBN

    9783642249549OnlineISBN

    9783642249556SeriesTitle

    LectureNotesinComputerScienceSeriesVolume

    7062SeriesISSN

    03029743Publisher

    SpringerBerlinHeidelbergCopyrightHolder

    SpringerVerlagGmbHBerlinHeidelbergAdditionalLinks

    AboutthisBook

    Topics

    ComputationbyAbstractDevices

    ArtificialIntelligence(incl.Robotics)

    PatternRecognition

    DataMiningandKnowledgeDiscovery

    SimulationandModeling

    ImageProcessingandComputerVision

    Keywords

    multifractaldetrendedfluctuationanalysis

    epilepticrats

    glutamatetransporter

    IndustrySectors

    Electronics

  • 23/12/2014 MultifractalAnalysisofIntracranialEEGinEpilepticusRatsSpringer

    http://link.springer.com/chapter/10.1007/9783642249556_42 4/5

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    eBookPackages

    eBookPackageenglishComputerScience

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    Editors

    BaoLiangLu (16)

    LiqingZhang (16)

    JamesKwok (17)

    EditorAffiliations

    16.DepartmentofComputerScienceandEngineering,ShanghaiJiaoTongUniversity

    17.DepartmentofComputerScienceandEngineering,TheHongKongUniversityofScienceandTechnology

    Authors

    TaoZhang(18)

    KunhanXu(18)

    AuthorAffiliations

    18.CollegeofLifeSciences,NankaiUniversity,Tianjin,PRChina,300071

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