Cassini pre-op analysis takes the mystery out of managing astigmatism:Identify more patients eligible for astigmatism correction and increase your premium procedure volume

Select the optimal Toric IOL power with confidence based on Cassini’s highly accurate TCA measurement

Place Toric IOLs or Arcuate Incisions for optimal effect with Cassini axis measurement ± 3°*

Your opportunity to expandMost people have astigmatism to some extent. A study of more than 6,000 cataract patients confirms that over 50% of cataract patients have a level of astigmatism that falls within the range correctable by a Toric IOL. That means that a premium IOL is an excellent option for a significant number of your cataract patients.

Source: Hill Distribution Data. Provided courtesy of Dr. Warren Hill.

More than 50% of patients are eligible for astigmatic correction

* Source: Kanellopoulos, Asimellis, Friess. CRSToday 2014

17.1%

11.2%

19.1%

14.8%

12.0%

7.8%

5.5%

3.7%2.9%

1.4%1.3% 0.9%

2.2%

< 0.25 0.25-0.50 0.50-0.75 0.75-1.00 1.00-1.25 1.25-1.50 1.50-1.75 1.75-2.00 2.00-2.25 2.25-2.50 2.50-2.75 2.75-3.00 > 3.00

Perc

enta

ge o

f pat

ient

s

8.7%

47.4%

43.8%

Commonly corrected

Not ideal for astigmatism

correction

Your opportunityto expand

Dioptric intervals in D

17.1%

11.2%

19.1%

14.8%

12.0%

7.8%

5.5%

3.7%2.9%

1.4%1.3% 0.9%

2.2%

< 0.25 0.25-0.50 0.50-0.75 0.75-1.00 1.00-1.25 1.25-1.50 1.50-1.75 1.75-2.00 2.00-2.25 2.25-2.50 2.50-2.75 2.75-3.00 > 3.00

Perc

enta

ge o

f pat

ient

s

8.7%

47.4%

43.8%

Commonly corrected

Not ideal for astigmatism

correction

Your opportunityto expand

Dioptric intervals in D

43.8% Your opportunity

to expand

What top surgeons have to say about Cassini

Getting the Axis right

Source: Kanellopoulos, Asimellis, Friess. CRSToday 2014

“Cassini is a better alternative for toric IOL planning and, as such, stands to pave the way for surgeons who have been hesitant to implant these premium lenses.”Douglas Koch, M.D. Baylor College of Medicine, Houston, TX, USA

“Superior in central corneal measurement to Placido and Scheimpflug in case of high irregularity.“A. John Kanellopoulos, M.D. Laservision Eye Institute, Athens, GreeceNew York University Medical School, New York, USA

”With Cassini preoperative planning, you can confidently treat your patient’s cataract with Toric IOLs and provide precise astigmatism correction in a single procedure.”Jonathan Solomon, M.D. Solomon Eye Associates, Bowie, MD, USA

Axis repeatability15

10

Stee

p A

xis

repe

atab

ility

in d

egre

es

Post-LASIK(n=51)

3.45

Keratoconus(n=95)

3.12

Pre-cataract corneas <1.00D (n=75)

3.03

4

3

2

1

0

Improved patient comfortl The latest version of Cassini provides reduced illumination levels during acquisition for improved patient comfort

Faster acquisitionsl Low illumination levels combined with auto-capture lead to faster acquisitions

Reliable resultsl Trusted point reflection technology

Platform for all future developmentsl The latest version of Cassini will be the platform for all future developments

Total Corneal Astigmatism Cassini uses patented multi - colored LED point - to - point ray tracing to provide a GPS - like analysis of the cornea along with high- resolution images utilized for surgical guidance.

The unique measuring principle enables highly accurate and repeatable measurements of the Total Corneal Astigmatism.

Cassini provides important information to properly select the appropriate astigmatism correction and axis orientation.

CAS

-510

-000

4-C

For more information:Cassini USA - +1 888 660 6965Cassini Global - +31 70 399 31 12info@cassini-technologies.comwww.cassini-technologies.comCassini Technologies BV, Anna van Buerenplein 40A, 2595DA, The Hague, The Netherlands.

l Multicolor LED Ray-Tracing combined with 2nd Purkinje Imaging Technologyl Anterior Axis repeatability within 3 degrees

l Display K-values per zone, with 3mm K-simulation data summaryl Keratometric indices display of Steep, Flat and Average in Diopters and millimeters for Anterior, Posterior and Total Corneal Astigmatism

l Auto and Manual Capturing with joystick positioningl Accuracy verification with Quality Factorsl Auto Photopic pupil size, White-to-White and Pupil Centre Off-set (Angle KAPPA) detectionl Topographic indices: E (Shape factor), e (eccentricity), Q (Asphericity), p (form factor)l Keratoconus screening indices: SAI (Surface Asymmetry Index), SRI (Surface Regularity Index)l Anterior Corneal Aberrations: Individual numeric parameter analysis and total HOA parameter displayl Instantaneous Iris and Scleral registration

l Submicron accuracy due to 679 Multicolor LED’s

l Pupillometry programs - Mesopic & Photopicl External Ocular Photographyl Topographic maps - Axial, Refractive, Tangential, Elevation, High Order Aberrations, Iris Registration and Color Image Registrationl Multiple color keys for topography maps customizationl Incorporated Patient Management programl USB, Various Report printing options, PDF, JPG, PNG

Cassini Specifications

Axis

Magnitude

Capture

Accuracy

Technology

Weight 15 kg/33 lbs

440 mm/17”320 mm/13”

550 mm/22”