Nano-BiomimeticsNano-Biomimetics

Team Team ГГ

Nano-biomimetics?Nano-biomimetics?

What is nano-biomimetics?What is nano-biomimetics? Biological self-assemblyBiological self-assembly Viral assemblyViral assembly Gecko FeetGecko Feet

What is nano-biomimetics?What is nano-biomimetics?

Utilizes biological mechanisms to create Utilizes biological mechanisms to create materialsmaterials Mimicking biological self-assembly processesMimicking biological self-assembly processes Using single biological units as a building block Using single biological units as a building block

along with inorganic materialsalong with inorganic materials Mimics biology at the molecular levelMimics biology at the molecular level

Synthesizing structures that mimic biological Synthesizing structures that mimic biological structuresstructures

Utilizing biological mechanismsUtilizing biological mechanisms

Atom-precise manipulation yields composite Atom-precise manipulation yields composite materials and nano-scale structures with materials and nano-scale structures with desirable propertiesdesirable properties

Parallel self-assembly processes achieve Parallel self-assembly processes achieve precision with high speed and reproducibilityprecision with high speed and reproducibility

Biological self-assemblyBiological self-assembly

Bottom-up fabrication processBottom-up fabrication process Continuing miniaturization of devices in Continuing miniaturization of devices in

nanotechnologynanotechnology Nature already assembles its smallest Nature already assembles its smallest

components into ordered structurescomponents into ordered structures

Biological self-assembly: applicationsBiological self-assembly: applications

Genetically Engineered Proteins for Inorganics Genetically Engineered Proteins for Inorganics (GEPIs)(GEPIs) MethodsMethods BiopatterningBiopatterning

Neuron growth on patterned substratesNeuron growth on patterned substrates

Biological self-assembly: applicationsBiological self-assembly: applications

Viral assembly: biologyViral assembly: biology

Abalone shell mostly Abalone shell mostly chalk, but 3000x chalk, but 3000x stronger because of stronger because of crystal structurecrystal structure

Very difficult to Very difficult to assemble crystals, assemble crystals, requires precise requires precise control in 3-Dcontrol in 3-D

Viral assembly: biomimeticViral assembly: biomimetic

Genetically engineered Genetically engineered virus attaches to virus attaches to molecule of building molecule of building materialmaterial

Viruses orient Viruses orient themselves in solution, themselves in solution, producing well-ordered producing well-ordered liquid crystalliquid crystal

Viral assembly: applicationsViral assembly: applications

Procedure can easily scale upProcedure can easily scale up Multiple applicationsMultiple applications Better materialsBetter materials

Mimicking biological structuresMimicking biological structures

Top-down approach using lithography, Top-down approach using lithography, scanning probes, CVD, sputter coating, and scanning probes, CVD, sputter coating, and many other techniques normally unassociated many other techniques normally unassociated with biologywith biology

Requires very precise manipulationRequires very precise manipulation

Gecko feet: biologyGecko feet: biology

Millions of Millions of hairs called hairs called setaesetae

Fiber radius is Fiber radius is nanometer-scalenanometer-scale

Adhesion due to Adhesion due to van der Waals van der Waals and capillary and capillary forcesforces

Gecko feet: biomimeticGecko feet: biomimetic

Use electron beam Use electron beam lithography and dry lithography and dry etching to create etching to create synthetic polymer hairssynthetic polymer hairs

Attach to flexible baseAttach to flexible base Palm-sized piece can Palm-sized piece can

support a humansupport a humanQuickTime™ and a

TIFF (LZW) decompressorare needed to see this picture.

Gecko feet: applicationsGecko feet: applications

Nano-biomimetics!Nano-biomimetics!

Create materials with novel propertiesCreate materials with novel properties Synthesize existing bio-materials in larger Synthesize existing bio-materials in larger

quantitiesquantities Integrate biomolecules and materials with Integrate biomolecules and materials with

inorganic ones for hybrid systemsinorganic ones for hybrid systems

ReferencesReferences Bio-assemblyBio-assembly

Sarikaya, Mehmet. "Moleucular biomimetics: nanotechnology through biology.“ Nature Materials Sept. 2003.Sarikaya, Mehmet. "Moleucular biomimetics: nanotechnology through biology.“ Nature Materials Sept. 2003. Gyorvary, Erika S. "Biomimetic Nannostructure Fabrication: Nanolithographic Lateral Patterning and Self-Assembly Gyorvary, Erika S. "Biomimetic Nannostructure Fabrication: Nanolithographic Lateral Patterning and Self-Assembly

of Functional Bacterial S-Layers at Silicon Supports." 11 Dec. 2002. Nano Letters. Vol. 3. 2004. 315+of Functional Bacterial S-Layers at Silicon Supports." 11 Dec. 2002. Nano Letters. Vol. 3. 2004. 315+ Zhang, Shuguang. "Fabrication of novel biomaterials through molecular self-assembly." Nature biotechnology Oct. Zhang, Shuguang. "Fabrication of novel biomaterials through molecular self-assembly." Nature biotechnology Oct.

2003.2003. Quinion, Michael. "Turns of Phrase: Biomimetics." World Wide Words. 22 Nov. 1997. Quinion, Michael. "Turns of Phrase: Biomimetics." World Wide Words. 22 Nov. 1997.

<http://www.worldwidewords.org>.<http://www.worldwidewords.org>. Viral Assembly:Viral Assembly:

http://www.sunlandimports.comhttp://www.sunlandimports.com http://www.sciencemag.org/cgi/content/full/296/5569/892http://www.sciencemag.org/cgi/content/full/296/5569/892 http://www.pnas.org/cgi/content/full/100/12/6946http://www.pnas.org/cgi/content/full/100/12/6946 http://web.mit.edu/giving/spectrum/fall05/building_on_nature.htmlhttp://web.mit.edu/giving/spectrum/fall05/building_on_nature.html http://pubs.acs.org/cgi-bin/sample.cgi/nalefd/2004/4/i01/html/nl0347536.htmlhttp://pubs.acs.org/cgi-bin/sample.cgi/nalefd/2004/4/i01/html/nl0347536.html

Gecko foot:Gecko foot: http://www.andrew.cmu.edu/user/gshah/Project_modeling.htmhttp://www.andrew.cmu.edu/user/gshah/Project_modeling.htm http://photos.wildmadagascar.org/images/uroplatus_fimbriatus-0143.shtmlhttp://photos.wildmadagascar.org/images/uroplatus_fimbriatus-0143.shtml http://www.houstonvoice.com/2004/6-18/view/actionalert/action.cfmhttp://www.houstonvoice.com/2004/6-18/view/actionalert/action.cfm http://onnes.ph.man.ac.uk/nano/Publications/Naturemat_2003.pdfhttp://onnes.ph.man.ac.uk/nano/Publications/Naturemat_2003.pdf

Spiderman: http://spiderman.sonypictures.comSpiderman: http://spiderman.sonypictures.com