Nanotechnolgy and Medicine, together or alone!

Presentation Topic:

Nanomedicine

Seyed Mohammad Motevalli

Prof. Deliang

Spring 2016

Nanotechnology map

What is Nanotechnology ?Nanotechnology is the engineering of functional systems at the molecular scale. In its original sense, 'nanotechnology' refers to the projected ability to construct items from the bottom up, using techniques and tools being developed today to make complete, high performance products

Nanomedicine

Nanomedicine

Biology

ChemistryNanotechnol-ogy

Definition Of Nanomedicine

• Nanomedicine is defined as the monitoring, repair, construction and control of human biological systems at the molecular level, using engineered nanodevices and nanostructures.

• The detection and controlled manipulation of human biological system at the molecular level via engineered nanodevices and/or nanostructures.

“An Engineered Nanodevice”

Why Nanomedicine ?•Diseases are mainly caused by damage at the molecular and cellular level•Today’s surgical tools are huge and imprecise in compari-son

“Today’s surgery and surgical tools”

Goals of NanomedicineEnd goal of nanomedicine is improved diagnostics, treatment and prevention

Goals of NanomedicineUltimate goal is to integrate detection, diagnostics, treatment and prevention of disease into a personalized single platform

Recent and future breakthroughs in medicineNanotechnology holds key to a number of recent and future breakthroughs in medicine

Cancer Treatments• Because of their small size, nanoparticles

can pass through interstitial spaces between necrotic and quiescent cells.

• Tumor cells typically have larger interstitial spaces than healthy cells

• Particles collect in center bringing therapeutics to kill the tumor from inside

Detection of CancerBreast Cancer Cells Healthy Cells

• On the left, cancer cells fluorescence.• On the right, healthy cells show minimal

fluorescence.

Types of contrast agents used for MRI

Drugs and contrast agents

Advantages of Nanomedicine

•Drug delivery to the exact location.•lower side effects.•Molecular targeting by nanoengineered devices•Detection is relatively easy.•No surgery required.•Diseases can be easily cured.

Disadvantages

•Not fully practical yet.•High cost.

Major Areas of Development of Nanomedicine

• Prevention and control• Early detection • Imaging• Multifunctional Therapeutics

Conclusion•Although realization of the full potential of nanomedicine may be years or decades away, recent advances in nanotechnology-related drug delivery, diagnosis, and drug development are going to change the medicine landscape. •Nanotherapies could be, in the long term, much more economical, effective and safe and could greatly reduce the cost of current medical procedures.•So, Nanomedicine is the future of medicine.