NANOMEDICINE

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OVERVIEW• Statistics

• What is nanomedicine ?

Applications

1) Tumors

2) Nanoinjectors

3) Surgery

4) Neuro-electronic interfaces

Ayman Ibrahim

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STATISTICS

• Nanomedicine is a large industry, with nanomedicine sales reaching 6.8 billion dollars in 2004, and with over 200 companies and 38 products worldwide, a minimum of 3.8 billion dollars in nanotechnology R&D is being invested every yearAyman Ibrahim

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WHAT IS NANOMEDICINE ?

• It is the usage of Nanotechnology for treatment, diagnosis, monitoring, and control of biological systems-“nanomedicine is the medical application of nanotechnology”Ayman Ibrahim

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VIDEO

Ayman Ibrahim

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TUMORDiagnosis• Seek out cancer

cells , targeting and attach to them.(Quantum dots or nanoshells coated with gold.)

Treatment• Kill tumor cells

selectively using specific receptors that attach only to the tumor cells.

Ayman Ibrahim

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VIDEO

Ayman Ibrahim

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NANOINJECTORS•nanoinjector based on a single carbon nanotube that is only 25 nm in diameter.

•This can be inserted into a single cell.

•The material is held in place by a chemical linkage that is sensitive to the cell interior.

•Once the tube is inside the cell, the linkage is broken and the material is released.

•This technique will be of great use to cell biologists, allowing them to overcome many of the limitations of existing microinjection techniques.

Ayman Ibrahim

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SURGERY• At Rice University, a flesh welder

is used to fuse two pieces of chicken meat into a single piece.

• The two pieces of chicken are placed together touching.

• A greenish liquid containing gold-coated nanoshells is dribbled along the seam.

• An infrared laser is traced along the seam, causing the two sides to weld together.

• solve the difficulties and blood leaks caused when the surgeon tries to restitch the arteries and wounds. Ayman Ibrahim

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NEURO-ELECTRONIC INTERFACES

• Neuro-electronic interfacing is the construction of nanodevices that will permit computers to be joined and linked to the nervous system as to control and detect nerve impulses .

Ayman Ibrahim

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NEURO-ELECTRONIC INTERFACES

• The computers will be able to interpret, register, and respond (particpate)to signals the body gives off when it feels sensations. The demand for such structures is huge because many diseases involve the decay of the nervous system .

Ayman Ibrahim

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NEURO-ELECTRONIC INTERFACES

• Also, many injuries and accidents may impair the nervous system resulting in dysfunctional systems and paraplegia.

• If computers could control the nervous system through neuro-electronic interface, problems that impair the system could be controlled so that effects of diseases and injuries could be overcome.

Ayman Ibrahim

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NEURO-ELECTRONIC INTERFACES

• It’s a sort of like a Remote for the body where u could monitor body signals and also send signals to different body organs.

Ayman Ibrahim

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THANKS

Ayman Ibrahim

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REFERENCES• American institute of physics

• Reviews in the journal Nanomedicine.

• Brooks BR, Bruccoleri RE, Olafson BD, States DJ, Swaminathan S, Karplus M (1983). “CHARMM: A program for macromolecular energy, minimization, and dynamics calculations“. J Comp Chem 4: 187–217.

• Brunger et al. “Trypsinogen-Trypsin Transition: A Molecular Dynamics Study of Induced Conformational Change in the Activation Domain”.

• Centre of Relevance and Excellance in NDDS-Pharmacy department

• The M. S. University of Baroda VADODARA.

• http://en.wikipedia.org/wiki/Nanomedicine

Ayman Ibrahim