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NANYANG TECHNOLOGICAL UNIVERSITY CV Form for Academic Staff (Part-I)

Name : Kwoh Chee Keong Present Appointment : Assoc Prof School : School of Computer Engineering Division : Division of Information Systems Date of 1st Appointment : 1 Apr 1992 Academic Qualifications: (State Name of University, year of award & class of honours) BEng(Hons) Cl 1 - National University of Singapore - 1987 MSc(IndEng) - National University of Singapore - 1991 DIC PhD - Imperial College of Science, Technology and Medicine, University of London - 1995 PGDIPTHE - Nanyang Technological University – 1999 10 year Long Service Award - 2001 15 year Long Service Award – 2006 20 year Long Service Award – 2011 Professional Qualifications/Memberships: (State date of membership) The Institution of Engineers Singapore, Senior Member 2005 - Present BMERC Fellow 2005 - Present Association for Medical and Bio-Informatics, Singapore, Member 2004 - Present Imperial College Alumni Association of Singapore (ICAAS), Lifetime member 2002 - Present Summary of Working Experience: (with dates)

1 Nov 2006 – 30 Sep 2013; Jan 2002 – Jun 2006

Programme Director, MSc (Bioinformatics)

1 Jan 2007 – 31 Mar 2013; 19 May 1997 - 31 Mar 2003

Deputy Director, Biomedical Engrg Research Centre, NTU

1 Jan 2006 – 31 Dec 2007 Deputy Director, Biomedical & Pharmaceutical Engineering Cluster (BPE) Cluster July 2004 – July 2008 Associate Professor, Div of Bioengineering, School of Chemical and Biomedical

Engineering 1 Jan 2000 - Present Associate Professor, SCE 1 Jan 1999 - 31 Dec 1999 Assistant Professor, NTU 1 Jan 1996 - 31 Dec 1998 Lecturer, NTU 1 Apr 1992 - 31 Dec 1995 Lecturer (ASDS), NTU Jul 1989 - Mar 1992 System Specialist, Singapore Computer Systems Pte Ltd Jul 1988 - Jun 1989 Systems Engineer, Singapore Computer Systems Pte Ltd May 1987 - Jun 1988 Programmer Analyst, Singapore Computer Systems Pte Ltd

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CV Form for Academic Staff (Part-II)

Name: Kwoh Chee Keong School: SCE

Dr. Kwoh Chee Keong is currently in the School of Computer Engineering since 1993. His is the Programme Director, MSc (Bioinformatics) and Deputy Director, Biomedical Engrg Research Centre, NTU. He received his Bachelor degree in Electrical Engineering (1st Class) and Master in Industrial System Engineering from the National University of Singapore in 1987 and 1991 respectively. He received his Ph.D. degrees from the Imperial College of Science, Technology and Medicine, University of London in 1995. His research interests include Data Mining and Soft Computing and Graph-Based inference; applications areas include Bioinformatics and Biomedical Engineering. He has done significant research work his research areas and published many quality international conferences and journal papers. His is in the Editorial Board Members of The International Journal of Data Mining and Bioinformatics; TheScientificWorldJOURNAL; Network Modeling and Analysis in Health Informatics and Bioinformatics (NetMAHIB); Theoretical Biology Insights; and Bioinformation. He has been Guest Editor for many journals such as JMMB; International Journal on Biomedical and Pharmaceutical Engineering and others. He has been often invited as a organizing member or referee and reviewer for a number of premier conferences and journals, including GIW, IEEE BIBM, RECOMB, PRIB, BIBM, ICDM, and iCBBE just to name a few. Dr. Kwoh is a member of The Institution of Engineers Singapore, Association for Medical and Bio-Informatics, Imperial College Alumni Association of Singapore (ICAAS). He has provided many service to professional bodies, and the Singapore and was conferred the Public Service Medal by the President of Singapore in 2008.

A. TEACHING (1) Text-books, book chapters, monograph, software Edited Books

1. Proceeding of 2nd International Conference on Biomedical and Pharmaceutical Engineering 2009 2. Proceeding of International Conference on Biomedical and Pharmaceutical Engineering 2006 3. JMMB special editor on “Moving Technology Towards Better Patient Care.” 2005 4. Proceeding of 1st International Bioengineering Conference, 2004

(2) Development of teaching materials Served the Curriculum Committee in

1. Medical School Curriculum Development And Stimulating Collaboration Group (March 2010 - Present) Curriculum for NTU Medical School (2009 – March 2010): Under the direction of Jan Carlstedt-Duke (Prof), Director of NTU Medical School and Medical Programme, represent CoE to work with TTSH on the curriculum development.

2. Curriculum for MSc in Bioinformatics: From August 2001 to June 2002, I worked with Vice-Dean (Academic) SCE, Head, Natural Science of NIE, Vice-Dean (Academic) of SBS and Professor from MPE and EEE to structure the new MSc in Bioinformatics.

3. Curriculum for BioEngineering, SCBE, CoE: From July 2004 – July 2008, I was holding joint appointment in the School of Chemical and Biomedical Engineering and was working with the Heads on the Biomedical Engineering Degree.

Planed and/or lectured subjects in

1. BI6105 Advanced Biology Update the syllabus on Part II of Biochemistry to focus more on the flux balance analysis in addition to Protein function; Enzymes & enzyme catalysis; Enzyme kinetics; Regulation of enzyme activity; Metabolic pathways; Energetics of metabolism; Control of metabolic pathways; Role of membranes; Metabolic network in higher organisms; Analysis & modeling of metabolic control as a doorway to bioinformatics.

2. BI6102 Introduction to Programming for Bioinformatics Proposed and design the lab component forf BI6128, which is used to introduce and equip the students with the needed skill to operate within the unix and linux environment; write programs in C and Perl scripts. After this course, students should be able to complete a programming assignment and be ready to apply the acquired skill for the remainder of this programme and beyond.

3. BI6192: " Integrative Bioinformatics, Data Analysis and Models in Genomics" work with BII to proposed and design the syllabus.

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4. BI6193 “Special Topics: Current computational methods and databases for protein sequence and structure analysis” work with BII to proposed and design the syllabus.

5. BG2011 Computational Methods in Biomedical Engineering (2004-07): Use of numerical methods to solve problems in science and engineering, with emphasis on biomedical engineering. Linear and non-linear algebraic equations. Optimization. Least-squares regression and interpolation. Numerical differentiation and integration. Numerical solutions of ordinary differential equations (ODE). Applications to statistical analysis. Applications to design of experiments.

6. BI6123 Methods and Tools of Proteomics (2007): Proteomics study and identify protein structure, interactions of protein/protein and protein/DNA and biology of organisms. We will further introduce the newly developed technology for the quantitative analysis of protein expression and function on a genome-wide scale.

7. BI6102 and SC448 Introductory Bioinformatics (2005,06,07,08): Basic bioinformatics concepts. databases, tools and applications.

8. BI6103 Computational Biology (2006,09-10): 9. BG3011 Biocomputing (2005, 06): Introduction the new course of biocomputing for students in SCBE, the

subject is first offered in July 2005; It covers Concepts; Bioinformatics databases; Sequence alignment; Phylogeny and protein structure prediction.

10. BI6104 Biostatistics (2003,04,05): First offered in July 2003, this course equipped the students in MSc with Knowledge of statistics, experimental design and statistical learning.

11. CE307 Computer Peripherals (1996 – 2000): re-design the course to include start-of-the-art techniques such as PRML, USB and Bluetooth.

12. M495 & M6524 Medical Assist Surgery (2000-2002): Co-planed and lectured the final year and MSc elective for Biomedical Engineering.

13. Digital Signal Processing (1992): Planed and lectured the final year elective for the computer engineering. (3) Short courses Planned and develop a workshop for Multi-Media University, Malaysia in “Algorithms in Bioinformatics” over 6 weekends from February - May 2009 Engaged by STEE(T&S) to conduct 4 weeks of Visual Display system module in the “Advanced flight simulator knowledge and Development phase” for Royal Thai Air Force Duration: 28 Jul 2008 to 3 Oct 2008 (4) Teaching Index

09/10 10/11 11/12

Index Sample

Size Index

Sample Size

Index Sample

size Lecture 85.29 49 85.00 41 86.34 77 Tutorial 83.54 17 69.6 19 86.2 48

(5) Service as examiner I have been appointed as examiner for confirmation and thesis.

- Examination of Post-graduate students in 2012 PhD thesis examiner: Liu Qian (SCE) Feng Xuesong (SCBE) Confirmation: Li Shaohua (SCE) - Examination of Post-graduate students in 2011

Confirmation: Wu Pengcheng (SCE) Li Zhenhua (SCE)

- Examination of Post-graduate students in 2010 PhD thesis examiner: Mr Md. Tawhidul Islam (MACQUARIE UNIVERSITY),

Mohammad Asif Khan (NUS) Jia Jia (NUS, Sup: Chen Yu Zong) Nguyen Quang Huy (SCE)

Confirmation: Chiew Wei Ming (SCE) Li Zhenhua (SCE)

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Nai Hong Hwa Francis (SCE) Wee Jing Fai Angela Jean (SCE)

- Examination of Post-graduate students in 2009 PhD thesis examiner: Olivo Miotto (NUS), Rajapakse Menaka Priyadharsani (SCE) Le Minh Nghia

Rajapakse Menaka Priyadharsani (NTU) Confirmation: Le Minh Nghia (SCE), Iti Chaturvedi (SCE), Chen Xianshun (SCE)

- Examination of Post-graduate students in 2008 PhD thesis examiner: Zhang Hailei (NUS)

Rajapakse Menaka Priyadharsani (NTU) Confirmation: FARIDEH FAZAYELI (EEE)

- Examination of Post-graduate students in 2007 PhD thesis examiner: Li Hu (NUS) PhD Confirmation: Gao Xiao Bin - Examination of Post-graduate students in 2006

Examination of Thesis: Du Zhuhua (PhD), Liu Weigo (PhD), Yap Yi-Lwern Kevin (Meng), Liu Weiguo FY confirmation: Mr Chen Hongjun (MPE), Cui Zhanhua, Nguyen Van Hien, Shen Li, Yang Xiao (PhD, SCE),

Yu Yiting - Examiner for PhD 2005: Abdul Wahab Bin Abdul Rahman, Zhao Jianhui - Examination of Post-graduate students in 2004/05

Examination of Thesis: Ho Sy Loi (PhD), Khin Myo Win (PhD) FY confirmation: Mr Chen Hongjun (MPE), Nguyen Van Hien - Examination of Post-graduate students in 2003/04 Examination Of Thesis: Sergey V Izraylit (MSc)

B. RESEARCH (1) Awards

Recognitions Date 1. The Winner of URECA Poster Competition 2011 - Titanium Award 2011 2. Outstanding Paper Award, for the work entitled “Predition of Shared

Regulatory Motifs from Upstream DNA Database for Gallus Gallus.” in The International Conference on Biomedical and Pharmaceutical Engineering 2006 (ICBPE2006) 2006. Singapore.

2006

The grant from 1998 to 2001, titled “Augmented Reality for Prosthesis Cup Placement” which I was the Principle Investigator with Dr. Yeo Seng Jin and Dr. Yung Shing Wai from the Department of Orthopaedic Surgery, Singapore General Hospital as co-PI lead to a report on 7th Feb 2009 in Straits times “SGH to share expertise in computer aided surgery”, A FILM of computer-assisted knee surgery by doctors at the Singapore General Hospital (SGH) will be sent to orthopaedic surgeons in 130 countries. (2) Citations

Research Output Summary Indicate total number and number in last three years (Jan 2009 – Present). For last 3 years, indicate number as first and last authorship Note: • Please ensure LNCS publications

are counted as conference papers.

• Ignore all student authors while counting first and last authorships

Total

count Last 3 Years (Jan’09 – Present)

Count First/Last Author No. of journal papers 56 23 15 / 1 No. of conf. papers 129 31 28 / 3 No. of Book chapters 4 1 0 / 0 No. of Edited books 4 1 1 / 0 No. of Authored books 0 / No. of patents 1 /

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Publication Impact Indicate citation count and H-index (attach citation reports generated by Scopus, Web of Science, and Harzing’s Publish or Perish.

Citation Count H-Index Google Scholar 765 15 Scopus 297 10 Web of Sciences 213 9

Count and List of Refereed Publications and Patents for the Period (Jan 2011 – Present) Include all publications and patents. Indicate number as first and last authorship Note: •

Review period (Jan’11 – Present)

Count First/Last Author No. of journal papers 14 10 / 0 No. of conf. papers 11 11 / 0 No. of Book chapters 1 1 / 0 No. of Edited books 0 / No. of Authored books 0 / No. of patents 1 /

(3) Achievements with local significance

Research Recognition and Other Innovative Achievements List awards, prizes and other noteworthy research achievements for the period Jan 2008 – Present (indicating clearly dates of awards)

Recognitions / Achievements Date 1. Straitstimes reported “SGH is going to share

expertise in computer aided surgery” by my past collaborator, Dr Yeo Seng Jin, who continued the work from MOE grant of

$288K for augmented reality application in orthopaedic surgery

7th Feb 2009

(4) Achievements earning significant publicities for the University

a) Dr. Yeo Seng Jin and Dr. Yung Shing Wai from the Department of Orthopaedic Surgery, Singapore General Hospital continued our initial work from the grant between 1998 to 2001, titled “Augmented Reality for Prosthesis Cup Placement” which I was the Principle Investigator lead to a report on 7th Feb 2009 in Straits times “SGH to share expertise in computer aided surgery”, A FILM of computer-assisted knee surgery by doctors at the Singapore General Hospital (SGH) will be sent to orthopaedic surgeons in 130 countries.

b) Our research group (http://mrcas.mpe.ntu.edu.sg/ ) held the first research open house on 2 Oct 1999 in NTU as part of the event of NSTB Techmonth.

c) Our research group represented NTU in NSTB’s Techmonth Maniafest 99 at Ngee Ann City, Civic Plaza. 11-12 Sept 1999.

d) The project on augmented reality prostate visualisation was featured on the Straits Times on 28 Jan 99. e) ARORA project was featured on 15 Dec 98 in the Lian He Zaobao of Singapore.

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(5) Service as editor and associate editor for international journals Services Period 1 Editorial board of Network Modeling and Analysis in Health

Informatics and Bioinformatics (NetMAHIB) journal to be published by Springer

2012 - present

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Editorial Board Members of The International Journal of Data Mining and Bioinformatics, from Inderscience

June 2011 - present

3 Editorial Board of TheScientificWorldJOURNAL medical sciences, life sciences, and environmental sciences Impact Factor of 1.524.

August 2011 - present

4 Editorial Board, Network Modeling and Analysis in Health Informatics and Bioinformatics (NetMAHIB) Springer

June 2011 to May 2014

5 Guest Editor for JMMB special issue editor 2009 6 Editorial Board of Theoretical Biology Insights March 2008 - Present 7 Editor, International Journal on Biomedical and Pharmaceutical

Engineering Jan 2007 – Present

8. Editor, Bioinformation (indexed by Pubmed) – Journal May 2005 – Present 9. Review Board of International Journal of Medical Robotics

and Computer Assisted Surgery 2006 - Present

10 Editor, Bioinformation (indexed by Pubmed) – Journal May 2005 – Present 11 Guest Editor for JMMB special editor on “Moving Technology

Towards Better Patient Care.” 2005

(6) Service as external examiner for PhD thesis Examiner for PhD: Liu Qian (SCE), 2011 Feng Xuesong (SCBE), 2011

Jia Jia (NUS), 2010 Mr Md. Tawhidul Islam (MACQUARIE UNIVERSITY), 2010 Mohammad Asif Khan (NUS) , 2010 Olivo Miotto (NUS), 2009

Zhang Hailei (NUS), 2008 Li Hu (NUS, DOC), 2007 Li Haiquan (NUS, DOC) 2006 Liu Huiqing (NUS, DOC) 2005 (7) Invited presentations at scientific meetings/workshops

1. Invited speaker for 2012 symposium on Emerging Technologies in Biomedical and Healthcare under NTU-CGU MOU. 10th April 2012

2. Invited speaker for NHG Research Admin Roundtable, “"NTU Research in Bioinformatics" 28th Nov 2011

3. Invited spearker at "Next-Gen Bioinformatics" Session of FAOBMB (Federation of Asian and Oceanian Biochemists And Molecular Biologists) Singapore Conference on 5 to 7 October 2011 at Biopolis Singapore

4. NTU‐CoE Workshop in “Engineering in Medicine”, tilted “Computer Aided Therapy”, 26th November 2009

5. NTU-BII Workshop “Towards Prediction of TCR Recognition of HLA/Peptide Complexes form A Structural Analysis.” 28 Sep 2009.

6. Workshop on Education in Bioinformatics and Computational Biology (WEBCB) (InCob2009) “Bioinformatics Programme at NTU” 7 Sep 2009.

7. NTU-UC Berkeley Workshop Invited Talk, “Computational Discovery of Vaccine Target” 23 and 24 March 2009

8. Plenary talk in the First Singapore Symposium on Computational Biology (SYMBIO 2008), “Machine Learning in Epitope-Based Vaccine Design” 1 Aug 2008.

9. International Conference on Computational Systems Biology, Fudan U, Shanghai, July 22, 2006 10. HP-CAST 2005, “HPC applications in BIRC” May 2005, Krakow Poland 11. BII 2005, “Information Content Based Algorithm for Identification Of Essential Attributes Toward

Discovering Disease-Specific Gene Regulatory Networks.” 12. I2R-KAIST workshop (2005), “Information Content Based Algorithm For Identification Of Eukaryotes

Gene Networks” 13. Bioscience Asia 2002, 'Life Science Initiatives and Milestones of NTU”, Taipei, Taiwan, 2002

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14. Bio-Ed 2002: The S* Bioinformatics Education Symposium, 11 March 2002 ( Monday), “Bioinformatics Programme in the Nanyang Technological University”

15. 2nd A*STAR-NRC Joint Singapore-Canada Workshop (17th –18th March 2003) on The Interface Of Biology With Information Technology, “The SVM Classification of Light Regulated Arabidopsis Genome Expression Profiles”.

(8) Service as a reviewer

For international Journals: Artificial Intelligence in Medicine; Bioinformation; BMC Research Notes; Cellular and Molecular Life Sciences (CMLS); IEEE Transactions on Knowledge and Data Engineering (TKDE) International Journal of Bioinformatics Research and Applications (IJBRA); International Journal of Data Mining and Bioinformatics (IJDMB); International Journal of Information Technology( IJIT); International Journal of Modern Physics B (IJMPB); Journal of Bioinformatics and Computational Biology (JBCB); Journal of Mechanics in Medicine and Biology (JMMB); Journal of Medical Imaging and Health Informatics; Medical Engineering & Physics; Medical Physics; Pattern Recognition Letter; The Journal of Biomedical & Pharmaceutical Engineering (JBPE); Theoretical Biology Insights VLSI –Signal Processing System

:

(9) Session chairman / (special) session organizer in conferences

Services Period 1. ICDM 2012 (http://icdm2012.ua.ac.be/) BioDM workshop on

"Biological Data Mining and its Applications in Healthcare Brussels, Belgium Program Committee

10 December 2012

2. 3rd International Conference on Computational Systems-Biology and Bioinformatics (CSBio2012) Program Chair

3-5 October 2012

3. The International Conference on Bioinformatics (InCoB) 2012 Program committee

3-5 OCT 2012

4. International Symposium on Network Enabled Health Informatics, Bio-Medicine and Bioinformatics (HI-BI-BI 2012, http://hibibi2012.cpsc.ucalgary.ca) Programme Committee

27-28 August 2012 in Istanbul

5. IEEE International Conference Bioinformatics & Biomedicine (BIBM2011) Workshop Chair

12-15 Nov 2011 Atlanta, GA

6. PC committee for our ICDM BioDM workshop 11- 14 Dec 2011 7. The InCoB/ISCB-Asia Joint Conference 2011

Programme Committee 30 Nov- 2 Dec 2011 KL, Malaysia

8. Joint 3rd International Conference on Biomedical & Pharmaceutical Engineering (ICBPE-2011) in conjunction with 2nd International Conference on Computational Systems - Biology and Bioinformatics (CSBio-2011) General Co-Chair

3-5 August 2011 Singapore

9. International Conference on Bioinformatics and Biomedical Engineering (iCBBE 2011), Wuhan, China Technical Program Committee

10-12 May 2011

10. The 4th International Conference on Bioinformatics and Biomedical Engineering (iCBBE 2010)

18th to 20th, 2010 Chengdu, China

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Organizing Committee 11. CoE Workshop on Biomedical Iimaging 4 March 2010

12. BIOSIGNALS - International Conference on Bio-inspired Systems

and Signal Processing (2010) Valencia, Spain International Program Committee

20-23 Jan 2010

13. 2nd International Conference on Biomedical and Pharmaceutical Engineering (2009) General Chair

December 2008 - December 2009

14. InCoB 2009 Conference Chairs

October 2008 – September 2009

15. 3rd International Conference on Bioinformatics and Biomedical Engineering (iCBBE 2009) Technical Program Committee

May 2008 – June 2009

16. 3rd Virtual Training Workshop on Bioinformatics Organizing committee

Aug 2008 – April 2009

17. RECOMB2008 Committee

30 Mar– 2 April 2008

18. GIW2007, back-to-back with AASBi07 and LBM07 Organizing Committee; Poster committee Session Chair

2-5 December 2007

19. BioDM Workshop on Data Mining for Biomedical Applications (BioDM 2007) in conjunction with the 11th Pacific-Asia Conference on Knowledge Discovery and Data Mining (PAKDD 2007) program committee

May, 2007

20. The 2nd IAPR Workshop on Pattern Recognition in Bioinformatics (PRIB 2007) Singapore program committee

1-2 October 2007

21. 2006 International Conference on Biomedical and Pharmaceutical Engineering, Singapore General Chair

11-14 December 2006

22. ICMMB XVth International Conference on Mechanics in Medicine and Biology Facilities Chair

6-8 December 2006

23. Algorithmic Biology: Algorithmic Techniques in Computational Biology Member

1 Jun - 31 Jul 2006

24. The Third Annual RECOMB Satellite Workshop on Regulatory Genomics Member

17-18 July 2006

25. 2006 IAPR Workshop on Pattern Recognition in Bioinformatics (PRIB’06) Program Committee

August 20, 2006

26. 10th Pacific-Asia Conference on Knowledge Discovery and Data Mining (PAKDD 2006) Workshop Program Committee

9-12 April 2006

27. 7th NTU-SGH Symposium Co-Chairman, NAEC, Singapore

10-12 Aug 2005

28. I2R-KAIST-NTU workshop Jointly organised by, I2R, KAIST and NTU

Feb 2005

29. Bioinformatics week (15-21 January 2005) in conjunction with APBC 2005 Jointly organised by AMBIS, I2R, BII, GIS, NTU and NUS

September 04 – January 05

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30. The Third Asia-Pacific Bioinformatics Conference 2005 APBC2005, Singapore Local organizing committee

January 04 – January 05

31. 1st International Bioengineering Conference in conjunction with 6th Annual NTU-SGH Biomedical Engineering Symposium September 8, 9 and 10, 2004 Marina Mandarin, Singapore. Treasurer

December 03 – September 04

32. 5th NTU-SGH Symposium Co-Chairman,

April 2002

33. 2003 International Conference on CYBERWORLDS Local program committee

June 2002 – December 03

34. International Conference on Bioengineering & Biosciences: The Next Frontiers to be held in MPE, Nanyang Technological University, Singapore, June 24-26, 2003. Local organizing committee

2002 – June 2003

35. BioGrid Computing Symposium Organiser: Asia Pacific Bioinformatics Network (APBioNet) Co-organisers: Nanyang Technological University

26 October 2001

(10) External research funding Research Proposals accepted

Duration (Start - End Date)

Source Amount (in S$1K units)

Involvement (PI, Co-PI, etc)

Description

1. Mar 2012- Feb 2015

MOE Tier-1 $200K Co-PI Methodological Investigation for Automatic Detection of Primary Angle Closure Condition (PAC) and PAC induced Glaucoma

2. Mar 2012- Feb 2014

MOE Tier-1 $150K Co-PI Bioinformatics Algorithms for Detecting Genetic and Epigenetic Determinants of Meiotic Recombination Hotspots from Genomic Data

3. Sept 2011- Sept 2012

MFRC Tier 1 $167,005 Collaborator Whole genome sequencing, single nucleotide polymorphisms, electron microscopy, Acinetobacter baumannii, lipopolysaccharide

4. April 2010 – March 2015

BII / SCE $4,412K 1 of 9 PIs Collaborative Research Programme On Bioinformatics Algorithms And Tools

5. Sep 2009- Aug 2012

IBM and Novaglobal

Pte Ltd

$125K PI Structural Analysis and Characterisation of Protein Complexes

6. Jul 2009- Jun 2011

NMRC S$ 196K Co-PI Genomic analysis and development of a new multilocus variable-number tandem-repeat analysis - scheme for molecular epidemiological typing of Acinetobacter baumannii

7. May 2009- May 2012

MOE Tier-2 S$ 1,000K PI Core-Attachment Based Mining For Protein Complexes & Small molecule Interactions

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8. March 2009-

Feb 2011 MOE Tier-1 S$ 96K Collaborator Characterization of novel extracellular

proteins produced by a newly-isolated strain of Bacillus subtillis.

9. Feb 2009- Jan 2011

Rolls-Royce Plc.

S$226K Co-PI Improved Design via Evolutionary Algorithms

10 11 Dec 2008 - 11 Dec 2011

MOE Tier 2 S$ 730K Collaborator Protein binding hotspots are water-free?

11 March 2008 – Feb 2011

BMERC $10K PI Analysis of Past DRG data for the study of LOS for better utilization of Hospital Resources SGH IRB approval for our research study: "Trends & risk factors for increased hospital length of stay". SGH funded 3 manpower for data collection.

12 October 2005 – Dec 2007

SPF 022-2005 funded by BPE Seed Grant

$5K PI Data Warehousing and Data Mining Analysis on Staphylococcus Aureus

13 Jan 2006 – Dec 2009

RSS by BMERC

$123K PI A novel approach for inter- to intra- network analysis of genetic diseases using high-throughput data

14 Oct 2002- Oct 2005

JT ARC 1/02 Jointly funded by A*Star & MOE

$658K Co-PI Neural Systems modeling with functional MRI

15 July 2004 – June 2007

SCE incubator initiative

$28K Co-PI SCE incubator proposal for “Evolutionary and Complex Systems Lab”

16 July 2002 - June 2006

NMRC: (NMRC/0834/2002)

$ 738,959

Co-PI The Application of ultrasound based augmented reality with the directional vacuum-assisted breast biopsy device in the treatment of breast cancer

17 12 March 2002 – March 2005

Compaq Computer Asia Pte Ltd

$1,500,000 Co-PI Research Grant for Bioinformatics Research Centre (BIRC)

18 March 2002 – March 2007

A-Star: $26,000,000

Co-PI Singapore-University of Washington Alliance (SUWA) in Bioengineering Distributed Diagnosis and Home Healthcare (D2H2)

19 Aug 2000 – March 2002

NTU: (CANES)

$1,500,000 Co-PI Proposal For Bioinformatics Research

20 July 1999 – June 2002

NTU and SGH

$35,000 and $30,000

PI Development of a robotic semi-automated remote handling system for radioiodine dispensing

21 March 1999 – AcRF: RG $121,000 Co-PI Functional MR Time-Series Analysis

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March 2002 45/98 22 December 1998

- May 2001 MOE AcRF: RG 5/98

S$288,532

PI Augmented Reality for Prosthesis Cup Placement

23 November 1998 – October 2003

MOE: ARP 1/98

S$935,029

Co-PI Robotic Skull Based Surgery

24 December 1997 – December 2000

MOE ARC 13/97

S$757,415 Co-PI Cardiovascular and Respiratory Systems' Signal Simulation, Processing and Analysis for ICU, OR and Telemedicine Applications.

25 December 1997 – 2001

JT ARC 17/97

S$ 1,200,000

Co-PI Strategic research: Interventive augmented reality for medical applications.

26 Nov 1994 – 1997

MOE ARC 3/94

S$577,900 Co-PI Surgeon Assistant Robot for Selected urological disorder.

Other funding

Duration Source Amount Remark 1. Dec 2009 Singapore Tourism Board

BE 1682 S$12,000

BE IN SINGAPORE INCENTIVE SCHEME:

CONVENTIONS

(11) Supervision of PhD and Master's Degree Dissertation PHD Students

1. Luay Aswad - A molecular basis of the 5-gene breast tumor aggressiveness grading signature (AGS) and its network – Co-Supervisor (2012 -)

2. Ouyang Xuchang - Accelerate The Protein-Ligand Docking (2010–) Main Supervisor 3. Thidathip Wongsurawat - Computational Analysis and Prediction of Specific Genomic Regions Forming

R-loop Structure and Chromosomal Variations Associated with Cancer - Co-Supervisor (2010 -) 4. Zhang Zhou - Knowledge Discovery In Post Genome-Wide Association Study For Glaucoma (2010-) Main

Supervisor 5. Su Tran To Chinh - Improving Smart Insulin By Structural Modification Of Concanavalin A Using Hidden

Markov Model And Molecular Dynamics Simulation (2010 -) Main Supervisor 6. Yang Peng - Core-Attachment Based Mining For Protein Compleses & Small-Molecule Interactions 7. Zhang Tianyou - Contact Network Based Framework For Infections Disease Intervention (PhD, 2005 - ) Main

Supervisor (2010 -) Main Supervisor 8. Wu Min - Joint Mining Of Coherent Patterns Across Multiple Data Sets (PhD, 2006 -) Main Supervisor 9. Stephanus Daniel Handoko - Multilevel Analysis Of Protein-Protein Interactions (PhD, 2006 -) Main

Supervisor 10. Adrianto Wirawan - Whole-Genome Discovery Of Transcriptional Regulator Binding Sites (PhD, 2005 -2009),

Main supervisor 11. Zhang Guanlan- Computational Epitope-Driven Vaccine Design (PhD, 2004 -2008), Main supervisor 12. Zheng Yun- Design Of Gene Expression Networks From Microarray Data (PhD, 2002-2006), Sole supervisor 13. Zou Qingsong - Object Based Volume Visualisation For Medical Imaging (PhD, 1998 – 2001), Sole supervisor 14. Zhao Jianhui- Human Animation from Motion Recognition, Analysis and Optimisation ( PhD, 2000-2003), Sole

supervisor

Master Student 1. Zhao Ying- Efficient Model And Feature Selection For SVM In Biomedical Data Analysis (M Eng, 2002-2004) ,

Sole supervisor 2. Jia Yiyu- Statistical Analysis Of Intron Phases At The Splice Sites Of Eukaryotic Genes ( M Eng, 2002-2004),

Main supervisor 3. Chen Yintao – Image Processing For Ultrasound Guidance System In Breast Lump Operation (M Eng,

2000 - 2002) 4. Wang Yan - Image-Based Indexing And Retrieval Of Trademark Logos, (M Eng, 1999 – 2001), Sole

supervisor

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5. Veena Mohan Bhajammanavar - Image Processing Of The Digital Mammogram For Segmentation And Characterization Of Microcalcifications, (M Eng, 1999 – 2000), Main supervisor

6. Misra Sabita - Time Series Analysis Of Ecg For Detection Of Premature Ventricular Contraction (M Eng, 1999 – 2000), Main supervisor

C. SERVICE (1) Awards

2011PA long Service Award 2008 August

National Day Awards 2008, The Public Service Medal (PBM) http://www.pmo.gov.sg/NationalHonoursandAwards/Pingat+Bakti+Masyarakat+(The+Public+Service+Medal).htm , conferred by the President of Singapore, Mr S R Nathan

2007 November, PAP Awards – Bronze

Long Service Medals – The medals are awarded to Party members for their dedication, loyalty and hard work• Bronze – minimum 10 years of service

(2) Service to the University (appointed by the President)

Date Appointment 1 Jan 2007 – 31 Mar 2013 Deputy Director, Biomedical Engrg Research Centre, NTU 1 Nov 2006 - Present Programme Director, MSc (Bioinformatics) Jan 2006 – Dec 2007 Deputy Director, Biomedical & Pharmaceutical Engineering Cluster (BPE) Cluster July 2004 – June 2008 Associate Professor, Div of Bioengineering Jan 2002 – Jun 2006 Programme Director, MSc (Bioinformatics) 1 Jan 2000 – Present Associate Professor, SCE 1 Jan 1999 - 31 Dec 1999 Assistant Professor, NTU 19 May 1997 - 31 Mar 2003 Deputy Director, Biomedical Engrg Research Centre, NTU 1 Jan 1996 - 31 Dec 1998 Lecturer, NTU 1 Apr 1992 - 31 Dec 1995 Lecturer (ASDS), NTU

(3) Other service to the University

Date Appointment1 Jan 2012 to 31 Dec 2013 Coordinator, SCE-BII Joint Research Programme March 2010 - Present Medical School Curriculum Development And Stimulating Collaboration

Group Jan 2006 – Present NTU-SGH Steering Committee Jan 2005 – Jul 2008 BioE Curriculum Coordinator Oct 2004 – 2005 MSc online web courses- Task Force 2002 – Present Programme Director of MSc in Bioinformatics July 1996 – Present Mentor, SCE & SCBE. 1999 – 2000 Institute of Biomedical Engineering (IMBE) Task Force 2002 – 2003 Committee on Graduate Courses in Engineering Sept 2004 – Oct 2004 Flagship programme proposal for Biomedical Computing March 2003 – March 2004 Work on SMA II proposal for Biomedical Engineering Jan – July 2003 Led the flagship programme for Biomedical Applications in SCE

(4) Public Service

April 2007 – Mar 2011 Chairman of Keat Hong Divison Inter-Racial And Religious Confidence Circle

Appointed by Ministry of Community Development, Youth and Sports

Jan 2007 – Dec 2013 Licensed Solemnizer Appointed by Ministry of Community Development, Youth and Sports

Nov 1999 – Nov 2013 Community Mediator Appointed by Ministry of Law as Community Mediator

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April 2007 – Mar 2011 Management Committee Loving Heart Multi-Service Centre

(Juroug Central) , Appointed by LIM BOON HENG, MINISTER, PRIME MINISTERS’ OFFICE

May 2009 – April 2015 Council Member Southwest Community Development Council

Appointed by Mayor, SW CDC

(5) Service to professional bodies

Services Period 1. External examiner for the Master of Bioinformatics programme at

the University of Malaya 2012-2014

2. Letter Of Appointment To NTU-NHG Innovation Seed Grant Review Committee

15-SEP 2011 to 14 SEP 2013

3. SINGA panel interview for the January 2012 September 2011 4. The Institution of Engineers, Singapore (IES)

Biomedical Engineering Technical Committee

Jan 2007 – Dec 2010

5. Singapore-China Association for Advancement of Science and Technology Deputy Director

Mar 2009 -

6. Judging Panel: The Imperial Alumni Association of Singapore (ICAAS) for Stockholm International Youth Science Seminar (SIYSS) which will be held in December 2008 in Stockholm, Sweden, in conjunction with the Nobel Prize Presentation Ceremony.

Jun – Dec 2008

7. Judging Panel of Singapore Science and Engineering Fair (SSEF)

Jan – March 2008

8 Judging Panel, Ngee Ann Poly webpage design competition Aug-Nov 2007

9. Member, Singapore Biomedical Compute Resource Management Committee (BII)

September 2002 – 2006

10.

Present: Mentors for National Science Scholars for scholar under A-Star

March 2002 –

11.

Reviewer: for I-Award for SPRING Singapore on innovation awards.

Sept 2003

(6) Service to society/local industry

Period of Involvement Name of Organisation Duration

External CONSULTATION/SPECIALIST WORK

UniSIM 26 February 2010 to 30 April 2010

Consultation ON VISUAL DISPLAY SYSTEMS

STEE(T&S) 28 Jul 2008 to 3 Oct 2008

Period of Involvement Name of Organisation Level/Description of Involvement June 2011 – Present Chua Chu Kang Magezine Editorial July 2006 – Present Family Life Champion Chairman Jan 2006 – Present Keat Hong Citizens' Finance Committee Chairman Jan 2006 – Dec 2010 Hong Kah Town Council Chairman, Estate and Amenity

14

Committee Jan 2006 – Present Keat Hong Citizens' Tender Committee Chairman Jan 2006 – Dec 2009 Fuhua Sec School, Parents Support

Group Chairman

July 2004 – Present Keat Hong Citizens' Consultative Committee

Chairman, Emergency Preparedness Group

2002 - Present PAP Keat Hong Branch Executive member, Head of Meet the People Sessions

Jan 2002 – Present Keat Hong Citizens' Consultative Committee

Secretary, Citizens' Consultative Committee

12 Aug 2000 - July 2004 School Advisory committee Choa Chu Kang Primary School

Vice-Chairman (July 2003 - July 2004)

Feb 1999 – Jan 2002 Hong Kah North CCC Secretary June 97 – 2001 PAP Community Foundation (HK North) Executive member, Auditor (child care

centres) June 97 – 2001 PAP Hong Kah North Branch Executive member, Meet the People

Sessions Jan 1998 – 2001 Yong PAP Hong Kah North Branch Vice Chairman, Chief Editor of Branch

Newsletter Feb 1999 – Jan 2002 Hong Kah North CCC Secretary Dec 1997 - Dec 2000 Sembawang - Hong Kah Community

Development Council Council member

Feb 1996 - Feb 1999 Hong Kah North Zone 8 Residents' Committee

Chairman (1998-99); Vice Chairman (1997-98); Assistant Secretary (1996-97)

D. WORKLOAD Teaching load For the academic year 2011/2012 only

Lecture – All Level of Subjects (hrs): 55 Tutorial (hrs): 13 Labs (hrs): 60 DDP/CIDP (hrs): No. of URECA/UROP students: No. of TERP/NRP students: 2 No. of FYP students: 4 No. of IA students: No. of directed reading MSc students: 3 No. of MSc thesis project students: 7

E. PUBLICATIONS Research Output Summary

Patent

1. Patent: "Computerised Boundary Estimation in Medical Images", Taiwan patent no. is 091446, valid from 11 Nov 1997 till 8 May 2017. US patent application no. is USSN 08/821,641, filed on 1 Mar 1996 (96-06116-3, Singapore).

Impact Factor Journal Papers

4.411 1 Zhang T, Fu X, Ma S, Xiao G, Wong L, Kwoh CK, Lees M, Lee GKK, Hung T. Effects of Temporal Factors in Combined Intervention of School Closure and Workforce Shift for Mitigating the Spread of Influenza. PLoS ONE2012.

4.877 2 Liu Q, Hoi SCH, Chinh STT, Li Z, Kwoh C-K, Wong L, Li J. Structural analysis of the hot spots in the binding between H1N1 HA and the 2D1 antibody: do mutations of H1N1 from 1918 to 2009 affect much on this binding? Bioinformatics2012;28(5).

1.866 3 Handoko SD, Ouyang X, Su CTT, Kwoh CK, Ong YS. QuickVina: Accelerating AutoDock Vina Using Gradient-based Heuristics for Global Optimization IEEE/ACM Transactions on Computational Biology and Bioinformatics2012.

1.472 4 Ellabaan MMH, Handoko SD, Ong YS, Kwoh CK, Bahnassy S, Elassawy F, Man HY. A Tree-structured Covalent-bond-driven Molecular Memetic Algorithm for Optimization of Ring-deficient Molecules. Computers and

15

Mathematics with Applications2012.

0.667 5 Baskaran N, Kwoh CK, Hui KM. Comprehensive Detection of Cancer Gene Expression Profiles and Gene Networks are Impacted by the Choice of Pre-Processing Algorithm and Gene-Selection Method. Int J Data Mining and Bioinformatics2012.

1.4 6 Zheng Y, Kwoh CK. A Feature Subset Selection Method Based On High-Dimensional Mutual Information. Entropy2011;13(4):860-901.

1.326* 7 Zhang T, Fu X, Kwoh CK, Xiao G, Wong L, Ma S, Harold Sohe G, Lee KK, Hung T, Lees M. Temporal factors in school closure policy for mitigating the spread of influenza. Journal of Public Health Policy2011.

4.351 8 Yang P, Li X, Wu M, Kwoh C-K, Ng S-K. Inferring Gene-Phenotype Associations via Global Protein Complex Network Propagation PLoS ONE2011 July 25, 2011.

4.926 9 Xie Z, Kwoh CK, Li X-L, Wu M. Construction of co-complex score matrix for protein complex prediction from AP-MS data. Bioinformatics2011 July 1, 2011;27(13):i159-i66.

1.694 10 Wu M, Li X, Kwoh CK, Ng SK, Wong L. Discovery of Protein Complexes with Core-Attachment Structures from TAP Data. Journal of Computational Biology2011;18:1 - 16.

7.836 11 Wongsurawat T, Jenjaroenpun P, Kwoh CK, Kuznetsov V. Quantitative model of R-loop forming structures reveals a novel level of RNA–DNA interactome complexity. Nucleic Acids Research2011.

4.21 12 Toh S, Prathipati P, Motakis E, Kwoh CK, Yenamandra S, Kuznetsov V. A robust tool for discriminative analysis and feature selection in paired samples impacts the identification of the genes essential for reprogramming lung tissue to adenocarcinoma. BMC Genomics2011;12(Suppl 3):S24.

13 Ouyang X, Handoko SD, Kwoh CK. CScore: A Simple yet Effective Scoring Function for Protein–Ligand Binding Affinity Prediction Using Modified CMAC Learning Architecture. Journal of Bioinformatics and Computational Biology2011;9(1):1-14.

14 Le T-V, Kwoh C-K, Lee K-H, Teo ES. Trend Analysis of Length of Stay Data via Phase-type Models. International Journal of Knowledge Discovery in Bioinformatics (IJKDB)2011.

3.781 15 Wu, M., Li, X., Chua, H. N., Kwoh, C.-K. & Ng, S.-K. Integrating diverse biological and computational sources for reliable protein-protein interactions. BMC Bioinformatics (2010).

4.328 16 Wirawan A, Kwoh CK, Schmidt B. Multi Threaded Vectorized Distance Matrix Computation on the Cell/BE and x86/SSE2 Architectures. Bioinformatics2010 March 26, 2010.

3.93 17 Li X, Wu M, Kwoh C-K, Ng S-K. Computational approaches for detecting protein complexes from protein interaction networks: a survey. BMC Genomics2010;11(Suppl 1):S3.

3.736 18 Handoko SD, Kwoh CK, Ong YS. Feasibility Structure Modeling: An Effective Chaperon for Constrained Memetic Algorithms. IEEE Transactions on Evolutionary Computation2009.

3.781 19 Wu M, Li X, Kwoh C-K, Ng S-K. A core-attachment based method to detect protein complexes in PPI networks. BMC Bioinformatics2009;10(1):169.

1.175 20 Wirawan A, Schmidt B, Zhang H, Kwoh C. High performance protein sequence database scanning on the Cell Broadband Engine. Scientific Programming2009;17(1-2):97-111.

21 Handoko SD, Kwoh CK, Ong YS. Classification-Assisted Memetic Algorithms for Equality-Constrained Optimization Problems. AI 2009: Advances in Artificial Intelligence2009:391-400.

4.589 22 Handoko SD, Kwoh CK, Ong YS. Feasibility Structure Modeling: An Effective Chaperon for Constrained Memetic Algorithms. IEEE Transactions on Evolutionary Computation2009;14(5):740 to 58.

5.895 23 Eisenhaber F, Kwoh C-K, Ng S-K, Sung W-K, Wong. L. Brief Overview of Bioinformatics Activities in Singapore. PLoS Computational Biology2009.

24 Zhou D, He Y, Kwoh CK. Extracting Protein-Protein Interactions from MEDLINE using the Hidden Vector State model. International Journal of Bioinformatics Research and and Applications2008.

3.493 25 Zhang GL, Khan AM, Srinivasan KN, Heiny AT, Lee KX, Kwoh C. Hotspot Hunter: a computational system for large-scale screening and selection of candidate immunological hotspots in pathogen proteomes. BMC Bioinformatics2008.

3.493 26 Wirawan A, Kwoh C, Hieu N, Schmidt B. CBESW: Sequence Alignment on the Playstation 3. BMC Bioinformatics2008;9(1):377.

1.825 27 Zhou D, He Y, Kwoh CK. Semi-supervised learning of the hidden vector state model for extracting protein–protein interactions. Artificial Intelligence In Medicine2007.

1.947 28 Zhang GL, Bozic I, Kwoh CK, August T, Brusic V. Prediction of Supertype-Specific HLA Class I Binding Peptides Using Support Vector Machines. Journal of Immunological Methods2007;320:143-54.

29 Lim C, Kwoh C, Chan Y, Chow P, Lie D, Foo J. Special Report Biomedical & Pharmaceutical Engineering Week (BPE Week) 2006. Journal of Biomedical & Pharmaceutical Engineering2007;1(1).

5.239 30 KWOH CK, NG PY. Network Analysis Approach for Biology. Cellular and Molecular Life Sciences2007.

31 CHAN CF, IRWAN K, LO C, NG I, KWOH CK. VOLUME VISUALIZATION FOR SURGICAL PLANNING SYSTEM Journal of Mechanics in Medicine and Biology2007 March 2007;7(1):55-64.

32 Zheng Y, Kwoh CK. Cancer Classification With MicroRNA Expression Patterns Found By An Information Theory Approach. JOURNAL OF COMPUTERS (JCP)2006 August 2006;1(5):30-9.

33 Zheng Y, Kwoh CK. Informative microRNA expression patterns for cancer classification. Data Mining for Biomedical Applications, Proceedings. Berlin: Springer-Verlag Berlin; 2006. p. 143-54.

0.636 34 Zheng Y, Kwoh CK. Dynamic Algorithm for Inferring Qualitative Models of Gene Regulatory Networks. The International Journal of Data Mining and Bioinformatics2006 September, 2006;1(2).

0.607 35 Zhao Y, Kwoh CK. Fast Leave-one-out Evaluation Guided Dynamic Gene Selection for Microarray Data Analysis. Soft Computing2006 FEB 2006;10(4):346-50.

36 Zhao J, Li L, Keong KC. MOTION RECOVERY BASED ON FEATURE EXTRACTION FROM 2D IMAGES. COMPUTATIONAL IMAGING AND VISION2006.

5.53 37 Zhang GL, Petrovsky N, Kwoh CK, August JT, Brusic V. PREDTAP: a system for prediction of peptide binding to

16

the human transporter associated with antigen processing. Immunome Research2006;2(1):3.

1.107 38 Zhao J, Ling L, Kwoh CK. 3D Posture Reconstruction and Human Animation from 2D Feature Points. Computer Graphics Forum (CGF)2005 (Accepted);24(4).

39 Zhou ZL, Kwoh CK. The Nearest Feature Midpoint - A Novel Approach for Pattern Classification. International Journal of Information Technology (IJIT)2005;11(1):1-15.

40 Zhao J, Ling L, Kwoh CK. Human Posture Reconstruction and Animation from Monocular Images Based on Genetic Algorithms. International Journal of Image and Graphics2005 2005/04;5(2):371-96.

41 Sakharkar KR, Chaturvedi I, Chow VTK, Kwoh CK, Kangueane P, Sakharkar MK. u-Genome: A database on genome design in unicellular genomes. In Silico Biology2005;5.

42 Teo MY, Kwoh CK, Somanesan S, Sundram FX. Development of a Robotic Dispensing System for Radioactive Iodine 131. SGH Proceedings2002;11(1):47-50.

1.066 43 Kassim, W.S.Ng, C.K.Kwoh. Review of locomotion techniques for robotic colonoscopy. IEEE Engineering in Medicine and Biology Magazine2002.

0.523 44 Zou Q, Kwoh CK, Ng W. Convex object based volume visualization: a formal proof and example. Computers & Graphics2001;25(5):857-73.

45 Yeo SJ, Yung SW, Kwoh CK, Wong TS, W.S.Ng, M.Y.Teo. Augmented Reality wtih X-ray Localisation for Total Hip Replacement. SGH Proceedings2001;9(4).

1.622 46 Ho G, Teo MY, Kwoh CK, Ng WS, Cheng WS. Computer- Assisted Transurethral Laser Resection Resection of the Prostate (CALRP):Theoretical and Experimental Motion Plan. IEEE Transactions on Biomedical Engineering2001;48(10):1125-35.

3.084 47 Ho G, Teo MY, Kwoh CK, Ng WS. Fundamental studies of transurethral robotic laser resection of the prostate by means of continuous wave Nd:YAG laser using Lasertrode lightguide. Journal of Biomedical Optics2001;6(2):244-51.

3.084 48 Ho G, Ng WS, Teo MY, Kwoh CK, Cheng WSC. Experimental study of transurethral robotic laser resection of the prostate using the LaserTrode lightguide. Journal of Biomedical Optics2001;6(2):244-51.

1.004 49 Fei B, Ng WS, Chauhan S, Kwoh CK. The safety issues of medical robotics. Reliability Engineering & System Safety2001;73(2):183-92.

2.346 50 Sabita M, Kwoh CK, Krishnan SM. A New Technique for Non-linear Time Series Analysis of ECG signal for Detection of Ventricular Premature Beats. Annals of Biomedical Engineering: The Journal of the Biomedical Engineering Society2000.

0.717 51 Bhajamanavar VM, Kwoh CK, Krishnan SM. Extraction of microcalcifications in a digital mammogram using regional watershed method. Journal of Digital Imaging2000;13(2 Suppl 1):127-30.

1.066 52 Tang SL, Kwoh CK, Teo MY, Ng WS, Ling KV. Augmented Reality Systems for Medical Applications. IEEE Transaction, Engineering in Medicine and Biology1998;17(3):49-58.

53 Kwoh C-K, Gillies DF. Probabilistic reasoning and multiple-expert methodology for correlated objective data. Artificial Intelligence in Engineering1998;12(1-2):21-33.

0.943 54 Kwoh CK, Teo MY, Ng WS, Tan SN, Jones LM. Outline of Prostate Boundary using Harmonics Method. Medical & Biological Engineering & Computing1998;36(6):768-71.

55 Chan C, Zhu C, Kwoh C, Teo M, Ng W, Foo K, Cheng C, Wong Y. Prostate biopsy using augmented reality 3D visualization. Critical Reviews in Biomedical Engineering1998;26(5):415-6.

3.008 56 Kwoh C-K, Gillies DF. Using hidden nodes in Bayesian networks. Artificial Intelligence1996;88(1-2):1-38.

Book Chapters /Thesis

1 Zhang T, Fu X, Goh RSM, Kwoh CK, Lee GKK. A Integrated Approach to Speed up GA-SVM Feature Selection Model", Computational In: Yoel Tenne C-KG, editor. Computational Intelligence in Optimization: Applications and Implementations Springer; 2010.Intelligence in Optimization-Applications and Implementations

2 D. Zhou, Y. He, and C. Kwoh, "From Biomedical Literature to Knowledge: Mining Protein-Protein Interactions," in Computational Intelligence in Biomedicine and Bioinformatics Springer, 2008.

3 S. Krishnan, C. Kwoh, S. Yan, and K. Chan, "ECG Signal Conditioning by Morphological Filters," in Advances in Cardiac Signal Processing: Springer, 2007.

4 C. Kwoh, "Probabilistic reasoning from correlated objective data." vol. PhD: Imperial College, London, 1995.

Conferences papers and other publications

1 Yang P, Wu M, Kwoh CK, Khil PP, Camerini-Otero RD, Przytycka TM, Zheng J. Predicting DNA Sequence Motifs of

Recombination Hotspots by Integrative Visualization and Analysis. 2012 International Symposium on Integrative Bioinformatics; Hangzhou, China2012.

2 Zheng Y, Kwoh CK. Improved time complexities for learning Boolean networks. The 4th RECOMB Conference on Regulatory Genomics, Systems Biology, and DREAM Challenges (IDIBELL); October 14-19; Barcelona2011.

3 Zhang Z, Kwoh CK, Liu J, Yin F, Wirawan A, Cheung C, Baskaran M, Aung T, Wong TY. MRMR Optimized Classification for Automatic Glaucoma Diagnosis. International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC'11); August 30 - September 3, 2011.; Boston, USA2011. p.

4 Xie Z, Kwoh C-K, Li X-L, Wu M, editors. Construction of Co-complex Score Matrix for Protein Complex Prediction from AP-MS Data. 19th Annual International Conference on Intelligent Systems for Molecular Biology and 10th European Conference on Computational Biology (ISMB/ECCB 2011); 2011; VIENNA, AUSTRIA.

5 Wu M, Kwoh C-K, Przytycka T, Li J, Zheng J. Prediction of Trans-regulators of Recombination Hotspots in Mouse Genome. IEEE International Conference on Bioinformatics & Biomedicine 12-15 November 2011 Atlanta, GA, USA: IEEE; 2011.

17

6 Toh SH, Prathipati P, Motakis E, Kwoh CK, Yenamandra SP, Thiery J-P, Kuznetsov VA. Discriminative microarray analysis reveals a global reprogramming of transcriptional profile in the human lung adenocarcinoma and predicts diagnostic and prognostic biomarkers. 4th Annual BioPharma IT World Asia 2011; 29-30 March; Singapore2011.

7 Le TV, Kwoh CK, Teo ES, Lee KH. Analyzing trends of hospital length of stay using Phase-type distributions. Workshop on Biological Data Mining and its Applications in Healthcare, Proc IEEE ICDM Workshop; Vancouver, Canada2011.

8 Kwoh CK, Chandrasekaran L, editors. Phylogenetic and mutational analysis of 2008, 2009 & 2010 neuraminidase of H1N1 influenza A. ACM Conference on Bioinformatics, Computational Biology and Biomedicine, ACM-BCB 2011; 2011; Chicago, Illinois, USA.

9 Kwoh CK, Bharija N. Comparative Study of Protein Interaction Networks for Virulence Factors of Co-existing Bacteria responsible for Nosocomial Infections. IEEE Symposium Series in Computational Intelligence 2011; April 2011; Paris (France)2011.

10 Jain D, Kwoh CK, editors. A Ranking-based Method to Predict Protein Function in terms of Gene Ontology. ICBPE2011 / CSBio2011; 2011 August 2011; Singapore.

11 Handoko SD, Kwoh CK, Ong YS. Classification-assisted Memetic Algorithms for Equality-constrained Optimization Problems with Restricted Constraint Function Mapping. IEEE Congress on Evolutionary Computation 2011; June 5-8, 2011; New Orleans2011.

12 Zheng C, C K Kwoh, C. Aquino, J. See, A. Chia, W. Lin, F.C. Ng_Lee, S.H. Ong, T. Aung, Chew PTK. Comparing Machine Learning Classifier for Diagnosing Different Angle Closure Mechanisms from Anterior Segment Optical Coherence Tomography Imaging. ARVO (Association for Research in Vision and Ophthalmology) Annual Meeting; May 2010; USA2010.

13 Zhang Z, Liu J, Kwoh CK, Sim X, Tay WT, Tan Y, Yin F, Wong TY, editors. Learning in Glaucoma Genetic Risk Assessment. Engineering in Medicine and Biology Society (EMBC), 2010 Annual International Conference of the IEEE 2010 Aug. 31 2010-Sept. 4 2010 Buenos Aires

14 Wu M, Li X, Chua H, Kwoh CK, Ng SK. Integrating Diverse Biological and Computational Sources for Reliable Protein-Protein Interactions. Ninth International Conference of Bioinformatics (InCoB2010); 26-28 Sept 2010; Tokyo, Japan2010.

15 Wirawan A, Kwoh CK, Schmidt B. Comparison of Sequence Alignment Tools on Accelerator Technologies. BIRC symposium Singapore2010.

16 Wirawan A, Kwoh CK, Hsu LY, Koh TH. INVERTER: INtegrated Variable numbER Tandem rEpeat findeR. CSBio 2010 : 1st International Conference on Computational Systems and Bioinformatics; Bangkok, Thailand: Springer; 2010. p. 151-64.

17 Toh SH, Yenamandra PS, Prathipati P, Kwoh CK, Kuznetsov VA. DISCRIMINATIVE MICROARRAY ANALYSIS IN PAIRED SAMPLES REVEALS A GLOBAL REPROGRAMMING OF TRANSCRIPTIONAL PROFILE IN THE HUMAN LUNG ADENOCARCINOMA AND PREDICTS EARLY DIAGNOSTICS BIOMARKERS. InCob; Tokyo, Japan2010.

18 Ramadoss R, Kwoh CK. A vaccine strategy for plant allergy by RNA interference - an in silico approach. CSBio 2010 : 1st International Conference on Computational Systems and Bioinformatics; Bangkok, Thailand: Communication in Computer and Information Science; 2010. p. 193-207.

19 Ong AL, Kwoh CK. Bioinformatics Approaches in Tuberculosis Vaccination Strategies by Whole Genome Sequence. IEEE International Conference on Bioinformatics & Biomedicine 18-21 Dec; Hong Kong2010.

20 Handoko SD, Kwoh CK, Ong YS. Feasibility structure modeling: an effective chaperone for constrained memetic algorithms. Evolutionary Computation, IEEE Transactions on2010;14(5):740-58.

21 Handoko SD, Chinh STT, Kwoh CK, Ong YS. Structural Analysis of (TCR–)HLA/peptide Complexes: An Initial Study. IEEE International Conference on Bioinformatics & Biomedicine 18-21 Dec; Hong Kong2010.

22 Chinh STT, Handoko SD, Schoenbach C, Li X, Kwoh CK. A Possible Mutation that Enables H1N1 Influenza A Virus to Escape Antibody Recognition. IEEE International Conference on Bioinformatics & Biomedicine 18-21 Dec; Hong Kong2010.

23 Bharija N, Kwoh CK. Comparative Study of Protein Interaction Networks for Virulence Factors of Co-existing Bacteria responsible for Nosocomial Infections. IEEE Symposium Series in Computational Intelligence 2011; April 11-15, 2011; Paris, France2010.

24 Baskaran N, Kwoh CK, Hui KM. Outcomes of Gene Association Analysis of Cancer Microarray Data are Impacted by Preprocessing Algorithms. IEEE International Conference on Bioinformatics & Biomedicine 18-21 Dec; Hong Kong2010.

25 Otto CN, Handoko SD, Kwoh CK. Identifying Patterns of Conformational Changes in HLA-A*0201-related Immunological Activities. International Conference on Biomedical and Pharmaceutical Engineering (ICBPE2009); Dec 2-4; Singapore2009

26 Kwoh C-K, Lee K-H, Le T-V. Using Survival Models to Analyze the Effects of Social Attributes on Length of Stay of Stroke Patients. International Conference on Biomedical and Pharmaceutical Engineering (ICBPE2009); Dec 2-4; Singapore2009

27 Zhang T, Soh SH, Fu X, Lee KK, Wong L, Ma S, Xiao G, Kwoh CK. HPCgen – A Fast Generator of Contact Networks of Large Urban Cities for Epidemiological Studies. International Conference on Computer Modelling and Simulation (CSSim 2009 - EUROSIM / CSSS); 7 - 9 September 2009; Brno, Czech Republic2009.

28 Zhang T, Fu X, Goh RSM, Kwoh CK, Lee GKK. A GA-SVM Feature Selection Model Based on High Performance Computing Techniques. SMC 2009; 2009.

29 Wirawan A, Schmidt B, Kwoh CK. Pairwise Distance Matrix Computation for Multiple Sequence Alignment on the Cell Broadband Engine. The International Conference on Computational Science 2009 (ICCS 2009); Baton Rouge, Louisiana, USA2009.

30 Lee K, Le T, Chee T, Kwoh C. Effects of Social Attributes on the Length of Stay of Stroke Patients in a Hospital. WONCA 2009 Asia Pacific Regional Conference; 4-7 June; Hong Kong2009.

31 Handoko SD, Kwoh CK, Ong YS. Classification-assisted Memetic Algorithms for Equality-constrained Optimization

18

Problems. The 22nd Australasian Joint Conference on Artificial Intelligence; 1 - 6 June, 2008; Australia2009.

32 Wu M, Li X-L, Kwoh C-K. Algorithms for Detecting Protein Complexes in PPI Networks: An Evaluation Study. Proceedings of Third IAPR International Conference on Pattern Recognition in Bioinformatics (PRIB 2008); Oct 20082008.

33 Wu M, Li X, Kwoh C-K, Ng S-K. Semantic labeling to identify reliable interactions in the protein interaction network. The 2nd International Conference on Bioinformatics and Biomedical Engineering (iCBBE 2008); May 16-18, 2008 Shanghai,China2008.

34 Nim TH, Kwoh CK, Wirawan A, Schmidt B. Applications of Heterogeneous Structure of Cell Broadband Engine Architecture for Biological Database Similarity Search. The 2nd International Conference on Bioinformatics and Biomedical Engineering (iCBBE 2008); May 16-18, 2008 Shanghai,China: IEEE Press; 2008. p. 5-8.

35 Nikhil Prasanna Jayan, Devasia Arun George, Keong KC. A Database for Analysis of SNP-Protein Structure Relationship and Predictive SNP-Metabolic Pathway Interaction for Disease Eradication. . A-Star UK-Spore Joint Symposium; 12 sept 2008; Singaproe2008.

36 Handoko SD, Kwoh CK, Ong YS, Lim MH. A Study on Constrained MA Using GA and SQP: Analytical vs. Finite-Difference Gradients. 2008 IEEE World Congress on Computational Intelligence (WCCI 2008); 1 - 6 June, 2008; Hong Kong2008.

37 Handoko SD, Kwoh CK, Ong YS. Using Classification for Constrained Memetic Algorithm: A New Paradigm. IEEE International Conference on Systems, Man, and Cybernetics 2008; 2008.

38 George DA, Kwoh CK, Jayan NP. PHOSPHORYLATION SITE PREDICTION TOOL FOR. CHANNEL PROTEINS USING STATISTICAL MACHINE. LEARNING TECHNIQUES. GIW; Australia2008.

39 Zhou D, He Y, Kwoh CK. Training the Hidden Vector State Model from Un-annotated Corpus. ICCS 2007: LNCS; 2007.

40 Zhou D, He Y, Kwoh CK. Effective Reranking for Extracting Protein-protein Interactions from Biomedical Literature. InCoB - Sixth International Conference on Bioinformatics 2007; Hong Kong2007.

41 Zhou D, He Y, Kwoh C, Wang H. Ant-MST: An Ant-Based Minimum Spanning Tree for Gene Expression Data Clustering. Pattern Recognition in Bioinformatics2007. p. 198-205.

42 Zhou D, He Y, Kwoh C. Semi-supervised Learning of the Hidden Vector State Model for Protein-Protein Interactions Extraction. IEEE Symposium on Computational Intelligence and Data Mining; 2007.

43 Zhang TY, Kwoh CK, Lim CS. A Comparison of Methods for Detection of Horizontal Gene Transfer, with Reference to Resistance Determinant Genes in Staphylococcus aureus Pattern Recognition for Bioinformatics PRIB 2007; 1-2 Oct 2007; Singapore2007.

44 Zhang GL, Khan AM, Srinivasan KN, Heiny A, Lee K, Kwoh CK, August JT, Brusic V. Hotspot Hunter: a computational system for large-scale screening and selection of candidate immunological hotspots in pathogen proteomes. InCoB - Sixth International Conference on Bioinformatics 2007; Aug 2007; Hong Kong2007.

45 Wirawan A, Kwoh CK, B. S. Parallel DNA Sequence Alignment on the Cell Broadband Engine. Parallel Processing and Applied Mathematics 2007; Gdansk, Poland: Lecture Notes of Computer Science; 2007. p. 1249-56.

46 Zhou D, He Y, Kwoh CK. Validating Text Mining Results on Protein-Protein Interactions using Gene Expression Profiles. The International Conference on Biomedical and Pharmaceutical Engineering 2006 (ICBPE2006) Dec 2006; Singapore2006.

47 Zhou D, He Y, Kwoh CK. Extracting Protein-Protein Interactions from the Literature using the Hidden Vector State. International Conference on Computational Science 2006 (ICCS 2006); May 28-31, 2006; University of Reading, UK: Lecture Notes in Computer Science (LNCS); 2006. p. 50-7.

48 Zheng Y, Kwoh CK. Informative MicroRNA Expression Patterns For Cancer Classification. PAKDD2006 BioDM Workshop; 2006.

49 Zhang T, Kwoh CK, Lim C. Studying Genetic Diversity by Mutations for Identification of Methicillin-resistant S.aureus. The First International Conference on Computational Systems Biology; July 20-23, 2006; Shanghai, China2006. p. 223-30.

50 Zhang GL, Tong JC, Zhang ZH, August JT, Zheng Y, Kwoh CK, Brusic V. Computational Models for Identifying Promiscuous HLA-B7 Binders based on Information Theory and Support Vector Machine. The International Conference on Biomedical and Pharmaceutical Engineering 2006 (ICBPE2006) Dec 2006; Singapore2006.

51 Zhang GL, Kwoh CK, August JT, Brusic V. Performance Evaluation of MULTIEPD1 on Prediction of MHC Class I Binders. The International Conference on Biomedical and Pharmaceutical Engineering 2006 (ICBPE2006) Dec 2006; Singapore2006.

52 SEAH SH, KWOH CK, BRUSIC V, SAKHARKAR MK, NG GS. Functional Prediction of Snake Neurotoxins ICARCV 2006; Dec 2006; Singapore2006.

53 Kwoh CK, Tan CH. Predition of Shared Regulatory Motifs from Upstream DNA Database for Gallus Gallus. The International Conference on Biomedical and Pharmaceutical Engineering 2006 (ICBPE2006) Dec 2006; Singapore2006.

54 Handoko SD, Kwoh CK, Ong YS, Zhang GL, Brusic V. Extreme Learning Machine for Predicting Hla-peptide Binding. In: Jacob C, Pilat ML, Bentley PJ, Timmis J, editors. Third International Symposium on Neural Networks (ISNN 2006); May 28-31, 2006; China: Springer; 2006.

55 Zheng YK, Chee Keong. A Feature Vector Selection Method for Cancer Classification. International Joint Conference of InCoB, AASBi and KSBI (BIOINFO2005); 21 Sept - 24 Sept 2005; Pusan, Korea2005. p. 23 -8.

56 Zheng Y, Kwoh CK. Classifying Eukaryotes With The Discrete Function Learning Algorithm. 3rd Asia-Pacific Bioinformatics Conference, APBC 2005; 2005.

57 Zheng Y, Kwoh CK. Identifying Simple Discriminatory Gene Vectors with an Information Theory Approach. IEEE Computational Systems Bioinformatics Conference CSB2005: IEEE Computer Society Press; 2005.

58 Tan SK, Chee Keong. Cytokine Information System and Pathway Visualization. International Joint Conference of InCoB, AASBi and KSBI (BIOINFO2005); 21 Sept - 24 Sept 2005; Pusan, Korea2005. p. 10-4.

19

59 Ong ZX, Tay JC, Kwoh CK. Applying the Clonal Selection Principle to find Flexible Job-Shop Schedules. International Conference for Artificial Immune Systems (ICARIS 2005); 14 ?17th August; Banff, Alberta, Canada2005. p. 442-55.

60 Kwoh CKK, Wui Lim. A Genome-Specific PCR Primer Design Program for Open Reading Frames. International Joint Conference of InCoB, AASBi and KSBI (BIOINFO2005); 21 Sept - 24 Sept 2005; Pusan, Korea2005. p. 147-50.

61 Kwoh CKH, Jing Ming; Loh, Kok Keong. HaBDiT: a Handy Biological Data Integration Tools. International Joint Conference of InCoB, AASBi and KSBI (BIOINFO2005); 21 Sept - 24 Sept 2005; Pusan, Korea2005. p. 470.

62 Devi SSK, Chee Keong; Kolatkar, Prasanna R. Comparison of Protein-Protein Interaction from Geometry and Biochemistry View with Computation-Driven Data. International Joint Conference of InCoB, AASBi and KSBI (BIOINFO2005); 21 Sept - 24 Sept 2005; Pusan, Korea2005. p. 402-6.

63 Chan CFIKCLK, Chee Keong;Ivan Ng. VOLUME VISUALISATION FOR SURGICAL PLANNING SYSTEM. 7TH NTU-SGH SYMPOSIUM 2005; 2005/082005.

64 Adi MZ, Yun; Kwoh, Chee Keong. Development of Correlation Based Feature Selection Method by Predicting the Markov Blanket for Gene Selection Analysis. International Joint Conference of InCoB, AASBi and KSBI (BIOINFO2005); 21 Sept - 24 Sept 2005; Pusan, Korea2005. p. 183-7.

65 Zhou Z, Li J, Kwoh CK. The SVM classification of light regulated Arabidopsis genome expression profiles. Proc of Biotech China 2004 - An International Conference; May; Beijing, China2004.

66 Zhou Z, Kwoh CK. AN EVOLUTIONARY LINEAGE FOR INTRON LOSS/GAIN IN FIVE EUKAYOTIC GENOMES. The Fourth International Conference on Bioinformatics of Genome Regulation and Structure (BGRS'2004); 2004.

67 Zhou Z, C.K.Kwoh. The Pattern Classification Based on the Nearest Feature Midpoints. International Conference on Pattern Recognition (ICPR); 2004.

68 Zheng Y, Kwoh CK. Dynamic Algorithm For Inferring Qualitative Models of Gene Regulatory Networks. IEEE Computational Systems Bioinformatics Conference, CSB2004; 2004.

69 Zheng Y, Kwoh CK. Reconstructing Boolean Networks from Noisy Gene Expression Data. Eighth International Conference on Control, Automation, Robotics and Vision, ICARCV 2004; 2004. p. 1049-54.

70 Zheng Y, Kwoh CK. IMPROVED MDL SCORE FOR LEARNING OF BAYESIAN NETWORKS. AISAT 2004 - International Conference on Artificial Intelligence in Science and Technology; 2004. p. 98-103.

71 Zheng Y, Kwoh CK. IDENTIFYING DECISION LISTS WITH THE DISCRETE FUNCTION LEARNING ALGORITHM. AISAT 2004 - International Conference on Artificial Intelligence in Science and Technology; Australia2004. p. 33-5.

72 Zhao Y, Kwoh CK. Fast Leave-one-out Evaluation and Improvement on Inference for LS-SVMs. International Conference on Pattern Recognition (ICPR); 2004.

73 Zhao J, Li L, Kwoh CK. A Model-based Approach for Human Motion Reconstruction from Monocular Images. 2nd International Conference on Information Technology for Application (ICITA 2004); 2004.

74 Zhao J, Li L, Kwoh CK. Human Motion Recovery Based on Extraction of Feature Points from Monocular Images. ICCVG 2004 - International Conference on Computer Vision and Graphics; 2004.

75 Zhang Y, Liu J, Kwoh CK, Jia Y. The sensitivity and rationality of pairwise linkage disequilibrium measures - a practical analysis. Genomic Signal Processing and Statistics (GENSIPS); 2004.

76 Zhang Y, Jia Y, Kwoh CK, Liu J. Comparison of four algorithms for haplotype inference problem. 2nd RECOMB satellite workshop on computational methods for SNPs and Haplotypes; 2004. p. 113-23.

77 Zhang Y, Jia Y, Kwoh C, Liu J. Application Comparison and Analysis of Computational Methods for Haplotype Inference Problem. RECOMB2004 workshop; USA2004.

78 Shi DM, Ng WS, Ling KV, Shao W, Chen H, Kwoh CK. Augmented Reality Assisted Sinus Surgery. 1st International Bioengineering Conference; 2004.

79 Jia Y, Zhang Y, Kwoh CK, Sundaram MK. INTRON/EXON: Which One Tells Us More About Coding Of Life? ?Evidence From Statistical Analysis Of Length Distribution. Genomic Signal Processing and Statistics (GENSIPS 2004); 2004.

80 Jia Y, Zhang Y, Kwoh CK, Gopalan V. Length Distributions Of Exons And Introns Imply The Evolutionary Constraints For Exon/Intron Length. Conference on Research in Computational Molecular Biology (RECOMB 2004); 2004.

81 Eng Y, Kwoh CK, Zhou Z. ON THE TWO-LEVEL HYBRID CLUSTERING ALGORITHM. AISAT 2004 - International Conference on Artificial Intelligence in Science and Technology, 2004; 2004. p. 138-42.

82 Zhou Z, Li J, Liew KM, Kwoh CK, Chia TF. The SVM classification of light regulated Arabidopsis genome expression profiles. Joint Singapore-Canada Workshop on "The Interface of Biology with Information Technology"; 2003.

83 Jia Y, Kwoh CK, Sakharkar MK, Kangueane P. Statistical analysis of symmetric exon sets in eukaryotic genes. International Conference on Genome Informatics (GIW 2003); 2003.

84 Zhao JH, Li L, Kwoh CK. Human Posture Reconstruction from Monocular Images. IASTED international Conference Computer, Graphics and Imaging (CGIM2002); 2002.

85 Li L, Zhao JH, Kwoh CK. HIERARCHICAL APPROACH FOR HUMAN ANIMATION. Visualization, Imaging, and Image Processing (VIIP 2002); 2002.

86 Kwoh CK. Life Science Initiatives and Milestones of NTU. Bioscience Asia 2002; 2002.

87 Agusanto K, Chuangui Z, Sing NW, Keong; KC. Photorealistic rendering for augmented reality. The First IEEE International Augmented Reality Toolkit Workshop (ART02); 29 Sept.2002. p. Page(s):2 pp.

88 Zou QS, Kwoh CK, Ng WS, Foo KT, Cheng C. An Internet Based Collaborative Surgical Planning System. 4th annual NTU-SGH Biomedical Engineering Symposium; 2001.

89 Zou QS, Kwoh CK, Ng WS, Chen YT. MRI Head Segmentation for Object Based Volume Visualization. The Seventh Australian and New Zealand Intelligent Information Systems Conference; 2001.

90 Zou QS, Kwoh CK, Ng WS. A Web Based Collaborative Volume Visualization System. Proceedings of 15th European Simulation Multiconference; 2001.

91 Zou QS, Kwoh CK, Ng WS. Interactive Surgical Planning Using Context Based Volume Visualization Techniques. Proceedings of International Workshop on Medical Imaging and Augmented Reality; 2001.

92 Yang KY, Kwoh CK, Seah E, Zhu CG, Yeo SJ, Ng WS. Use of augmented reality in acetabular fixation in total hip arthroplasty. 5th Computer Adided Orthopaedic Surgery (CAOS); 2001.

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93 Xiao d, Kwoh CK, Ng WS, Abeyratne UR. Rectal wall structure delineation and broken layer recognition by multigradient field active contour. The Seventh Australian and New Zealand Intelligent Information Systems Conference (ANZIIS); 2001.

94 Chen YT, Kwoh CK, Wee SB, Zou QS. Adaptive Expanding BSnake Model For Extracting Ultrasound Breast Lump Boundary. The Seventh Australian and New Zealand Intelligent Information Systems Conference (ANZIIS); 2001.

95 Zou QS, Kwoh CK, Ng WS. A Collaborative 3D Volume Visualization Pipeline. IEEE-EMBS Asia-Pacific Conference on Biomedical Engineering; 2000.

96 Wang Y, Kwoh CK, Khan GN, Suliman AH. Boundary Description for Trademark. Sixth International Conference on Control, Automation, Robotics and Vision (ICARCV2000); 2000.

97 Veena, Kwoh CK. Mathematical Morphology based Feature Extraction Technique for Classification of Microcalcifications in a Digital Mammogram. IEEE-EMBS Asia-Pacific Conference on Biomedical Engineering; 2000.

98 Tan EC, Xiao D, Kwoh CK. Area calculation of medical image onscreen. Proceedings of IEEE-EMBS Asia-Pacific Conference on Biomedical Engineering; 2000. p. 280-1.

99 Tan EC, Kwoh CK. Group-access control of E-medicine records. Proceedings of IEEE-EMBS Asia-Pacific Conference on Biomedical Engineering; 2000. p. 95-6.

100 Sabita M, Kwoh CK, Krishnan SM. Complexity measures of ECG signal for detecting a life threatening cardiac arrhythmia. 10th International Conference on Biomedical Engineering (10 ICBME) Biomedical Engineering in the New Millennium: Integration and Breakthroughs; Singapore2000.

101 Sabita M, Kwoh CK, Krishnan SM. A New Approach for Detecting and Delineation of QRS complex for PVC Detection. IEEE-EMBS Asia-Pacific Conference on Biomedical Engineering; 2000.

102 Sabita M, Kwoh CK, Krishnan SM. A New Technique for Non-linear Time Series Analysis of ECG signal. 2000 Annual Fall Meeting of the Biomedical Engineering Society; 2000.

103 Kwoh CK, Yeo SJ, Yung SW. X-RAY LOCALIZATION FOR TOTAL HIP REPLACEMENT. 3rd NTU-SGH Annual Scientific Symposium; 2000.

104 Khan LA, Kwoh CK, Fei BW, Ng WS. The image intensifier (II) distortion calibration method in X-ray localization for total hip replacement (THR). Conference of Society for Computer Applications in Radiology (SCAR); June 3-6; Philadelphia, Pennsylvania2000.

105 Ho G, Teo MY, Kwoh CK, Ng WS, Cheng WSC. Perspectives of transurethral robotic laser resection of the prostate; Vaporization and coagulation effects with the Nd:YAG laser. Proceedings of SPIE - The International Society for Optical Engineering; San Jose, CA, USA: Society of Photo-Optical Instrumentation Engineers; 2000. p. 252-61.

106 Fei BW, Kwoh CK, Ng WS. The hazard identification and safety insurance control (HISIC) for medical robot. World Congress on Medial Physics and Biomedical Engineering, 22nd Annual International Conf Of IEEE EMBS; 2000.

107 Chen YT, Kwoh CK. Lesion Boundary Enhancement using Threshold Directed. IEEE-EMBS Asia-Pacific Conference on Biomedical Engineering; 2000.

108 Chan KL, Kwoh CK, Sabita M, Krishnan SM. Nonlinear Techniques for Processing and Analysis of ECG Signals. Third Annual SGH-NTU Biomedical Engineering Symposium; 2000.

109 Bhajamanavar VM, Kwoh CK, Krishnan SM. Extraction of microcalcifications in a digital mammogram using regional watershed method. Society for Computer Applications in Radiology (SCAR 2000); 2000.

110 Bhajamanavar VM, Kwoh CK, Krishnan SM. Entropy-based thresholding for detection of microcalcifications in a digital Mammogram. 14th international congress and Exhibition Computer Assisted Radiology and Surgery (CARS 2000); 2000.

111 Sabita M, Kwoh CK, Krishnan SM. A quantitative method for ECG analysis for PVC detection. The International Conference on Medical Diagnostic Techniques & Procedures; Dec1999. p. 43-8.

112 Kwoh CK, Khan GN, Gillies DF. Automated Endoscope Navigation and Advisory System from Medical Image. SPIE's Int Conf on Physiology and Function from Multidimensional Images (Medical Imaging 1999); San Diego, California1999. p. 3660-25.

113 Khan LA, Kwoh CK, Fei BW, Ng WS. X-ray localization technique for total hip replacement operation in augmented reality for therapy (ART). 21st IEEE EMBS, 1st EMBS-BMES joint Conference; 1999.

114 Fei BW, Kwoh CK, Ng WS. Software design method for medical robot. 21st IEEE EMBS, 1st EMBS-BMES joint Conference; 1999.

115 Chee CF, Kwoh CK, Teo MY, Ng WS. Prostate Biopsy using Augmented Reality 3D visualisation. 18th Southern Biomedical Conference and the 2nd International Conference on Ethical Issues in Biomedical Engineering; 1999.

116 Chan CF, Kwoh CK, Teo MY, Ng WS. Tessellated surface reconstruction from 2D contours. Medical Image Computation and Computer-Assisted Intervention (MACCAI), 2nd International Conference; 1999. p. 297-308.

117 Chan C, Kwoh C, Teo M, Ng W. Tessellated Surface Reconstruction from 2D Contours. Medical Image Computing and Computer-Assisted Intervention – MICCAI’991999. p. 297-307.

118 Kwoh CK, Teo MY, Tang SL, Ng WS, Ling KV. Augmented Reality for Therapy. Inaugural Biomedical Engineering Symposium of NTU and SGH: Partnering for Healthcare Solutions; 23rd April 1998; Auditorium, College of Medicine Building, Singapore General Hospital1998.

119 Kwoh CK, Teo MY, Ng WS. Evalutation of computerised prostate boundary estimation in ultrasound images. 4th Asian Congress in Urology by Singapore Urological Association and Urological Association of Asia; 1998.

120 Kwoh CK, Teo MY, Mohan RS, Ng WS. Safety guidelines for medical robots. 4th Asian Congress in Urology by Singapore Urological Association and Urological Association of Asia; 1998.

121 Kwoh CK, Ng WS, Teo MY. Computer assisted prostate treatment ?past, present and future. 4th Asian Congress in Urology by Singapore Urological Association and Urological Association of Asia; 1998.

122 Kwoh CK. Radial Bas-relief (RBR) and Parametrically Deformable Model for Ultrasound Contour Determination. 4th Asian congress in Urology, organised by Singapore Urological Association and Urological Association of Asia; 17 Sep 98-20; Mandarin, Singapore1998.

123 Teo TT, Tan EC, Kwoh CK. Implementation of a 4.8 Kbps CELP Speech Coder on a TMS320C44 Processor Board. Proceedings of 1st International Conference on Information, Communications & Signal Processing (ICICS '97); 1997.

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p. 1168-71.

124 Kwoh CK, Ng WS, Teo MY, Jones LM. ROBOTIC TURP AND TREATMENTS OF BPH. International College of Surgeons and New Changi Hospital Combined Scientific Meeting; 1997.

125 Kwoh CK, Ng WS, Teo MY, Jones LM. Image guidance for robotic TURP using ultrasound. International College of Surgeons and New Changi Hospital Combined Scientific Meeting; 1997.

126 Kwoh CK, Ng WS, Teo MY, Jones LM. Interventive Augmented Reality. International College of Surgeons and New Changi Hospital Combined Scientific Meeting; 1997.

127 Kwoh CK, Gillies DF. Choice of error cost function for training unobservable nodes in Bayesian networks. Proceedings of 1st International Conference on Knowledge-based Intelligent Electronic Systems; 1997. p. 565-74.

128 Kwoh CK, Gillies DF. Estimating the Initial Values of Unobservable Variables in Visual Probabilitic Networks. Proceedings of the 6th International Conference, CAIP 95; Prague1995. p. 326-33.

129 Kwoh CK, Gillies DF. Using Fourier Information for the Detection of the Lumaen in Endoscope Images. Proceedings of the IEEE TENCON '94; 1994. p. 981-5.