(nasdaq: irgi) william blair growth stock conference june 25, 2003
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(NASDAQ: IRGI) William Blair Growth Stock Conference June 25, 2003. Safe Harbor Disclaimer. - PowerPoint PPT PresentationTRANSCRIPT
(NASDAQ: IRGI)
William Blair Growth Stock Conference
June 25, 2003
54787062
Statements contained in this presentation that are forward-looking are based on current expectations that are subject to a number of uncertainties and risks, and actual results may differ materially. Factors that might cause such a difference include, but are not limited to, risks associated with: the reduction in research and development activities by pharmaceutical and biotechnology clients, changes in government regulations, the effects of interest rate and foreign exchange fluctuations, our ability to attract and retain employees, the loss or delay of contracts due to economic uncertainty or other factors, our ability to efficiently manage backlog, our ability to expand our business through strategic acquisitions, competition within the industry and the potential adverse impact of health care reform. Further information about these risks and uncertainties can be found in the information included in the company’s recent filings with the Securities and Exchange Commission, including the company’s Registration Statement on Form S-1 and Form 10-K filed on February 18, 2003.
Safe Harbor Disclaimer
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Building the world’s leading and most profitable drug development
services company
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Strategy for Profitable Growth
Operational Overview
2002 Financial Overview
First Quarter 2003 Financial Overview
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Investment Summary
• Global market presence
• Full-service drug development capability
• Large market opportunity
• Established leadership position in pre-clinical development
• Unique position in clinical development
• Diversified revenue mix and client base
• Proven management team
• Track record of growth and profitability
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Company History
1964 Inveresk performs first pharmacology/toxicology studies (in Edinburgh)
1965 CTBR (Pre-clinical Americas) founded (in Montreal)
1988 Inveresk Clinical Research founded (in Edinburgh)
1989 ClinTrials Research founded (in Nashville)
1996 ClinTrials Research and CTBR merge
2001 Acquisition of ClinTrials by Inveresk Research
2002 NASDAQ listing (“IRGI”)
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Global Market Coverage
Origin of Clients - 2002
USA 56%
Europe 31%
Japan 7%
RoW 6%
Client Type
Pharma 56%
Biotech32%
Other 12%
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Full-service Drug Development Capability
Pre-clinical Testing, Toxicology, Drug Metabolism &
Pharmacokinetic Studies (DMPK)
Final Patent Application
File IND
Marketing Application
Market Approval
DiscoveryResearch
Development ResearchRegulatory
ReviewPost-Mktg
Review
Market segments covered by Inveresk Research
Basic Research
Genomics
Proteomics
Virtual chemistry
Synthesis
Biological testing
Pharmacological screening
Phase I
Phase II
Phase III
Phase IV
Clinical Trials
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Large Market Opportunity
100
110
120
130
140
150
160
170
180
1992 1993 1994 1995 1996 1997 1998 1999 2000 2001
Source: CMR International, IMS Health
Growth in R&D vs. Revenue (Indexed)
R&D Growth
Revenue Growth
8.5
9.811.0
12.5
14.3
16.3
7.6
0.0
2.0
4.0
6.0
8.0
10.0
12.0
14.0
16.0
18.0
20.0
1999 2000 2001 2002F 2003F 2004F 2005F
Market for Outsourced Drug Development Services
($ in billions)
Source: Frost & Sullivan
CAGR – 13.7%
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Pre-clinical Overview
• World #3 in toxicology
• World #1 in speciality toxicology
• Integrated laboratory sciences
• Established over 35 years ago
• 85% repeat business
• Diverse client base
• Focus on quality, value-added
• Clients - USA, Europe and Japan
% of 2002 Net Service Revenue
64%
Revenues - $142.2 million
1,830 Employees
Locations – Edinburgh, Scotland and
Montreal, Canada
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Clinical Overview
% of 2002 Net Service Revenue
36%
Revenues - $80.3 million
720 Employees
Locations – USA, UK, Germany, France, Spain, Italy,
Belgium, Poland, Czech Republic
• Key global capability
• Phase I-IV coverage
• European #4
• World class Phase I - 62 bed clinic with “first-into-man” focus
• ClinTrials integration completed successfully
• Further opportunity for revenue growth and improved profitability
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0.0% 1.0% 2.0% 3.0% 4.0% 5.0% 6.0% 7.0%
Major Pharma
Major Pharma
Biotech
Major Pharma
Major Pharma
Biotech
Major Pharma
Biotech
Biotech
Biotech
Major Pharma
Major Pharma
Major Pharma
Major Pharma
Pharma
Pharma
Biotech
Biotech
Biotech
Biotech
Highly Diversified Client Base
Top client – 5.9%
Top 5 clients – 21.1%
Top 20 clients – 43.2%
Percentage of 2002 Net Service Revenue
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Proven Management Team
Walter Nimmo
President & CEO
(15 years)
Mike Ankcorn
President - CTBR
(24 years)
Brian Bathgate
President - Europe
(12 years)
Pre-clinical
Nick Thornton
Corp. Development
(2 years)
Alastair McEwan President
(7 years)
Clinical
Paul Cowan
CFO (1
year)
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51.658.2 63.9 65.5
180.6
222.5
0.0
50.0
100.0
150.0
200.0
250.0
1997 1998 1999 2000 2001PF 2002
Track Record of Growth and Profitability
Acquisition of ClinTrials – April, 2001
(i) Excludes amortization of goodwill prior to 2002 and exceptional charges related to our IPO in 2002 of $54.6 million.
Net Service Revenue ($ in millions)
8.1 9.4 10.3 11.1
20.9
45.6
0.0
10.0
20.0
30.0
40.0
50.0
60.0
1997 1998 1999 2000 2001PF 2002PF
Acquisition of ClinTrials – April, 2001
Income From Operations(i) ($ in millions)
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Operational Overview
Strategy for Profitable Growth
2002 Financial Overview
First Quarter 2003 Financial Overview
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Response to Market Characteristics
IRGI ResponseKey Market Drivers
Drug Industry Trends:• Huge demand for new therapeutics• Impact of new technologies - genomics• Growth of “biotech” and biotech products• Increased “pharma” competition
Impact on Research & Development:• Increasingly demanding regulation• Escalating R&D expenditures• Need for improved R&D productivity
Industry Response:• Increasing and more focussed R&D• Greater trend to outsourcing• Need for global drug development
Strategic:• Continue focus in earlier development
stages – Pre-clinical, Phase I through early Phase III
• Differentiate through a higher value-added service offering
• Maintain global reach • Concentrate on areas with the highest
barriers to entry – toxicology, lab sciences• Maintain diverse, high quality client base• Provide solutions, not just scienceService Offering:• Focus on quality and responsiveness• Maintain broad based service offering• Address both pharma and biotech • Continue emphasis on speciality services• Leverage Pre-clinical/Clinical cross selling
opportunity
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Financials - Key Growth Drivers
• Maintain revenue growth in Pre-clinical, accelerate in Clinical
• Controlled capacity expansion in Pre-clinical and Phase I – to sustain/enhance operating margins
• Progress margin expansion in Clinical - towards target levels of 15% to 20%
• Continue migration of “old ClinTrials” clinical contracts to higher margin business – to be completed in 2003
• Maintain emphasis on cost control and improved business processes across all business areas
Target bottom line growth of over 20% per annum
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200520042003
Stage 1 - Montreal
Toxicology and Lab Sciences
Stage 1 - Edinburgh
Toxicology
Stage 2 - Edinburgh
Lab Sciences
Stage 2 - Montreal
Toxicology & Lab Sciences
Stage 1 – Clinical Europe
Phase I
Stage 1 – Clinical Americas Phase I
Key Elements for Organic Growth
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Operational Overview
2002 Financial Overview
Strategy For Profitable Growth
First Quarter 2003 Financial Overview
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2002 Key Highlights
• IPO completed in June; 12 million shares sold at $13.00 per share
• Net revenue up 42% to $222.5 million
• Pro forma operating income up 104% to $45.6 million
• Full-year operating margin 20.5%
• 2002 diluted EPS of $0.88, pro forma
• Cash flow from operations $51.3 million(i)
• Stage 1 Montreal pre-clinical expansion completed, on time and within budget, and pre-sold on a multi-year basis
• Reorganization and integration of former loss-making ClinTrials clinical businesses has progressed beyond expectations
(i) Before payment of accumulated shareholder loan interest.
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2002 Segment Results – Pro Forma
(i) Pro forma, excluding amortization in 2001 and exceptional charges in 2002 relating to the Company’s IPO.
22.3
4.5
22.4
43.5
9.0
45.6
0.0
10.0
20.0
30.0
40.0
50.0
60.0
Pre-clinical Clinical Total
+104%+95%
+100%
Income From Operations (i)
($ in millions)
95.2
61.1
156.3142.2
80.3
222.5
0.0
50.0
100.0
150.0
200.0
250.0
300.0
Pre-clinical Clinical Total
+49%
+31%
+42%
Net Service Revenue
($ in millions)
2001 2002
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Relative Profitability - 2002
0.0%
5.0%
10.0%
15.0%
20.0%
25.0%
30.0%
35.0%
Peer Group - Mean
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Review of Cash Flows
• Net cash provided by operations: $51.3 million, before deducting accumulated interest of $21.5 million on pre-IPO shareholder loans
• Capital expenditure: $25.5 million
• Cash flow (before accumulated shareholder loan interest paid) as a % of Pro forma net income - 155%
• Net DSO’s at year end: 30 (45 at December 30, 2001)
• Cash and equivalents at year end: $19.9 million
• Gross financial debt at year end: $68.0 million
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Operational Overview
First Quarter 2003 Financial Overview
Strategy For Profitable Growth
2002 Financial Overview
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Q1, 2003 Financial Highlights• Net service revenue up 8.5% to $57.7 million ($53.2 million in Q1, 2002)
• Income from operations $8.6 million ($5.2 million in Q1, 2002)
• Pro forma income from operations $9.2 million ($9.8 million in Q1, 2002)
• Significant rebound in activity levels at our Montreal-based pre-clinical operations
• Clinical revenues grew 14.3% year-on-year. Operating margin increased to 10.6% in Q1, 2003, from 4.1% in Q1, 2002
• Diluted EPS of $0.20, compared to a loss per share of $0.02 in 2002
• Pro forma diluted EPS of $0.22, a 22% increase over Q1, 2002
• Cash flow from operations $4.8 million, before capex of $4.3 million
• New business signings $76.6 million in Q1, 2003
• Confirmed backlog - $222 million at March 31, 2003
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Q1, 2003 Financial Results by Segment
10.4
0.8
5.2
9.8
8.8
2.3
8.69.2
0.0
2.0
4.0
6.0
8.0
10.0
12.0
14.0
34.5
18.7
53.2
36.3
21.4
57.7
0.0
10.0
20.0
30.0
40.0
50.0
60.0
70.0
Net Service Revenue ($ millions)
Income from Operations ($ millions)
+5%
+14%
+9%
-6%
+194%
-15%
20032002
Total Reported
Total Pro Forma
+64%
ClinicalPre-clinical
Pre-clinical
Clinical Total Reported
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Key Factors Influencing Q1, 2003 Results
• Volatility in short-term business flows in Montreal-based pre-clinical operations – strong rebound experienced in March/April
• Reduced levels of pass-through costs in European pre-clinical operation deflate revenue, but not profitability
• Continued recovery in clinical business – in terms of growth and profitability
• Transaction exchange losses recorded totaling $1.5 million – now hedged
• Social security costs on employee share option exercises booked in Q1 totaling $0.2 million
• Negative mark-to-market adjustment on interest rate swaps of $0.2 million
• Share offering costs of $0.7 million expensed in quarter
• Positive impact of Canadian and UK tax credits, reduced Canadian corporate tax rates and newly available UK tax deductions for share option expenses
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Moving Annual Total of Signed Contracts
Moving Annual Total of Signed Contracts – cumulative previous twelve months new signed contracts, net of cancellations
242.9
265.1 266.3 262.1271.2 274.4
100
125
150
175
200
225
250
275
300
325
350
Dec 01 Mar 02 Jun 02 Sep 02 Dec 02 Mar 03
$ m
illio
ns
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Confirmed Backlog
148.5165.0 171.8
193.2202.0 206.1 209.8
222.0
0
25
50
75
100
125
150
175
200
225
250
275
300
Jun 01 Sep 01 Dec 01 Mar 02 Jun 02 Sep 02 Dec 02 Mar 03
$ m
illio
ns
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Outlook and Strategy
• Continued strength in new business signings across all operations
• Rebound in Montreal-based pre-clinical operations experienced in March and April
• European pre-clinical operations experiencing continued strong demand for both toxicology and laboratory sciences services
• Clinical businesses continuing strong performance of 2002
• 2003 EPS forecast to total between $1.07 and $1.09, on revenue growth of 11% to 14%
• Continue to service our clients with quality, high value-added services
• Pre-clinical expansion on track, Stage 1 Montreal expansion pre-sold – leveraging our world leading capability
• Diverse revenue and client base, positions IRGI well for the future
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Investment Summary
• Global market presence
• Full-service drug development capability
• Large market opportunity
• Established leadership position in pre-clinical development
• Unique position in clinical development
• Diversified revenue mix and client base
• Proven management team
• Track record of growth and profitability