national institute of allergy and infectious diseases, nih
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National Institute of Allergy and Infectious Diseases, NIHNational Institute of Allergy and Infectious Diseases, NIH
Grant Opportunities and Management SymposiumGrant Opportunities and Management SymposiumNational Institute of Allergy and Infectious Diseases, NIHNational Institute of Allergy and Infectious Diseases, NIH
Grant Opportunities and Management SymposiumGrant Opportunities and Management Symposium
Overview & Funding OpportunitiesOverview & Funding Opportunities
Presented byPresented by
Paula S. Strickland, Ph.D., MPHPaula S. Strickland, Ph.D., MPHDirector, Office of International Extramural Activities (OIEA)Director, Office of International Extramural Activities (OIEA)
Division of Extramural ActivitiesDivision of Extramural Activities National Institute of Allergy and Infectious DiseasesNational Institute of Allergy and Infectious Diseases
National Institutes of HealthNational Institutes of HealthDepartment of Health and Human ServicesDepartment of Health and Human Services
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NIAID SymposiumNIAID SymposiumPurpose
• To provide information on funding opportunities;
• Assist researchers and administrators in better understanding NIH funding policies and the peer review process;
• To provide information on grants management.
Purpose
• To provide information on funding opportunities;
• Assist researchers and administrators in better understanding NIH funding policies and the peer review process;
• To provide information on grants management.
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OverviewOverview
About NIH & NIAIDGrant opportunities
& resources
Application process Advice on preparing
your application budget
Program: Scientific areas of interest
Manage NIH grant funds Fundable grant
Peer review process
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NIH Consists of 27 Institutes and CentersMission: To support biomedical and behavioral
research for the public good.
= Extramural only
NEI
NCI
NHLBI
NLM NINDS
NIMH
NIAMS
NINR
NCCAM
CIT
CC
NHGRI
NIANIAAA
NIAIDNICHD
NIDCD
NIDCR
NIDDK
NIDA
NIEHSOD
NIGMS
NCRR
NIBIBNCMHD
FIC
CSR
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NIAID NIAID Mission: “To conduct and support research that
strives to understand, treat, and ultimately prevent the multitude of infectious, immunologic, and allergic diseases that endanger the lives of millions of people nationally and globally.”
NIAID is the lead institute for infectious diseases and immunology research
Budget in FY 2007 is ~$4.3 billion Received a large allocation in FY 2003 for
biodefense research
Mission: “To conduct and support research that strives to understand, treat, and ultimately prevent the multitude of infectious, immunologic, and allergic diseases that endanger the lives of millions of people nationally and globally.”
NIAID is the lead institute for infectious diseases and immunology research
Budget in FY 2007 is ~$4.3 billion Received a large allocation in FY 2003 for
biodefense research
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NIAID PrioritiesNIAID Priorities
To Develop:
• An effective AIDS vaccine• Technologies and medical countermeasures against
Cat A-C agents and emerging infectious diseases• New medical counter measures for influenza• Medical interventions using immune tolerance
strategies• Better capacity in developing countries to support
clinical trials of vaccines and therapeutics for AIDS, malaria, TB, and other important global diseases
To Develop:
• An effective AIDS vaccine• Technologies and medical countermeasures against
Cat A-C agents and emerging infectious diseases• New medical counter measures for influenza• Medical interventions using immune tolerance
strategies• Better capacity in developing countries to support
clinical trials of vaccines and therapeutics for AIDS, malaria, TB, and other important global diseases
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NIAID Global ResearchNIAID Global Research
Research Funded in over Research Funded in over 100 countries100 countries
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Emerging & Re-emerging Infectious Diseases
Emerging & Re-emerging Infectious Diseases
NIAID supported research includes:
• Basic
• Applied
• Clinical
NIAID supported research includes:
• Basic
• Applied
• Clinical
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InfluenzaInfluenza
• Basic research
• Diagnostics
• Therapeutics
• Pre-pandemic and Pandemic vaccines
• Basic research
• Diagnostics
• Therapeutics
• Pre-pandemic and Pandemic vaccines
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Tuberculosis & MalariaTuberculosis & Malaria
• Multi-drug resistant (MDR) forms of Mycobacterium tuberculosis
• Extensively-drug resistant TB (XDR-TB),
• Malaria– Drugs– vaccines
• Multi-drug resistant (MDR) forms of Mycobacterium tuberculosis
• Extensively-drug resistant TB (XDR-TB),
• Malaria– Drugs– vaccines
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HIV/AIDS HIV/AIDS
• Pathogenesis
• Therapy/Care
• Prevention
• Vaccines
• Pathogenesis
• Therapy/Care
• Prevention
• Vaccines
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Biodefense ResearchBiodefense Research
Three areas of focus:• Infrastructure – safely conduct research on
dangerous pathogens• Basic research - microbes and host immune
defenses – foundation for applied research
• Medical countermeasures – targeted, milestone-driven– vaccines, therapeutics, and diagnostics
Three areas of focus:• Infrastructure – safely conduct research on
dangerous pathogens• Basic research - microbes and host immune
defenses – foundation for applied research
• Medical countermeasures – targeted, milestone-driven– vaccines, therapeutics, and diagnostics
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Immune-mediated DiseasesImmune-mediated Diseases
• Autoimmune and allergic diseases, asthma:– Immune Tolerance therapies– Asthma treatment and drug studies
• Autoimmune and allergic diseases, asthma:– Immune Tolerance therapies– Asthma treatment and drug studies
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The Search for Research FundsThe Search for Research Funds
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Funding Information Resource: InternetFunding Information Resource: Internet
• Timely information and updates
• Includes current and relevant information
• Funding opportunities - grants, contracts– policies, and other subjects of interest
to applicants
• Timely information and updates
• Includes current and relevant information
• Funding opportunities - grants, contracts– policies, and other subjects of interest
to applicants
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Search for Funding Sources
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U.S. Grants & Funding OpportunitiesU.S. Grants & Funding Opportunities
Grants.gov website:• Find grant opportunities
– 26 Federal grant-making agencies
• Register– Allows organization to apply for U.S. grants – Process in 3-5 business days (incomplete info
causes delays)
• Apply for grants• Find electronic submission resources• Track your application
Grants.gov website:• Find grant opportunities
– 26 Federal grant-making agencies
• Register– Allows organization to apply for U.S. grants – Process in 3-5 business days (incomplete info
causes delays)
• Apply for grants• Find electronic submission resources• Track your application
19http://www.hhs.gov/grants/index.shtml
DHHS Funding Opportunities
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NIH Funding Opportunities
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Funding OpportunitiesFunding Opportunities
• NIH Guide for Grants and Contracts – official publication listing NIH funding – policy notices
• Published weekly
• List grants and contracts– Request for Applications (RFA)– Program Announcements (PA)– Request for Proposals (RFP)
• NIH Guide for Grants and Contracts – official publication listing NIH funding – policy notices
• Published weekly
• List grants and contracts– Request for Applications (RFA)– Program Announcements (PA)– Request for Proposals (RFP)
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Choose the Appropriate Funding Instrument and Mechanism
Choose the Appropriate Funding Instrument and Mechanism
• Three major funding “instruments” to support extramural research– Grant – researcher decides the research to be
designed and approach
– Contract – government decides the research to fill a specific need
– Cooperative agreement – grant, but the awarding institute has substantial involvement in the project activities
• Three major funding “instruments” to support extramural research– Grant – researcher decides the research to be
designed and approach
– Contract – government decides the research to fill a specific need
– Cooperative agreement – grant, but the awarding institute has substantial involvement in the project activities
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Submission DatesSubmission Dates
Mecha-nism(s)
Program Description
ApplicationForm
Cycle IDue Date
Cycle II Due Date
Cycle IIIDue Date
R01 new Research Grant
SF 424 Feb 5 June 5 Oct 5
U01 new Research Grant
PHS 398 – transition to SF424 (on hold)
Feb 5 June 5 Oct 5
R03, R21 Other research grants
SF 424 Feb 16 June 16 Oct 16
new, renewal, resubmission, revision
AIDS and AIDS-Related Applications
Based on mechanism
May 7 Sept 7 Jan 7
( See NOT-OD-07-053 for change in AIDS receipt dates)
24http://era.nih.gov/ElectronicReceipt/files/Tips_for_International_Applicants.pdf
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NIAID Research Funding OpportunitiesNIAID Research Funding Opportunities
• Most RFA/PA - open to applicants from the private and public sectors, including small businesses.
• Check the Eligibility section to see if Foreign organizations are eligible.
• Read the complete RFA/PA for allowable costs
• NIAID related opportunities– www.niaid.nih.gov/ncn/budget/opps.htm
• Most RFA/PA - open to applicants from the private and public sectors, including small businesses.
• Check the Eligibility section to see if Foreign organizations are eligible.
• Read the complete RFA/PA for allowable costs
• NIAID related opportunities– www.niaid.nih.gov/ncn/budget/opps.htm
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Foundations and Other Funding Sources Foundations and Other Funding Sources
• Grant funding organizations outside of NIH that cover the same areas of science as the NIAID Funding Opportunities List
• www.niaid.nih.gov/ncn/budget/found.htm
• Grant funding organizations outside of NIH that cover the same areas of science as the NIAID Funding Opportunities List
• www.niaid.nih.gov/ncn/budget/found.htm
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NIH Grant Process NIH Grant Process
Peer reviewPeer review
Fundable Score & NIAID portfolioFundable Score & NIAID portfolio
Notice of Award (NoA)•Read NoA carefully
Notice of Award (NoA)•Read NoA carefully
Submit grant application Submit grant application
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SCIENTIFICREVIEW
ADMINISTRATOR
Key People in the ProcessKey People in the Process
PROGRAM OFFICER
OIE
A S
taff
APPLICANT
GRANTS MANAGEMENT
OFFICER
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NIAID International Assistance for Funded Investigators
NIAID International Assistance for Funded Investigators
• Program officers – research questions
• Grants management specialists – budget and allowable cost questions
• NIAID contractor (OIEA managed)– onsite grant and contract financial management information and training.
• Program officers – research questions
• Grants management specialists – budget and allowable cost questions
• NIAID contractor (OIEA managed)– onsite grant and contract financial management information and training.
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New Independent InvestigatorsNew Independent Investigators
Websites
ShorterReview Cycle
K99/R00Award
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New Investigator - Evolving DefinitionNew Investigator - Evolving Definition
Yes:• Small Grant (R03) • Academic Research
Enhancement Award (R15) • Exploratory/Developmental Grant
Phase I (R21) -- except R21/R33 • Shannon Award (R55) • High-Priority, Short-Term Project
(R56-Bridge) • Some career awards (K01, K08,
K22, K23, K25, or K99/R00)
Yes:• Small Grant (R03) • Academic Research
Enhancement Award (R15) • Exploratory/Developmental Grant
Phase I (R21) -- except R21/R33 • Shannon Award (R55) • High-Priority, Short-Term Project
(R56-Bridge) • Some career awards (K01, K08,
K22, K23, K25, or K99/R00)
No:• R01 • R21/R33 • R29 (no longer
awarded) • Other senior career
awards (K02, K06, K24, and K26).
No:• R01 • R21/R33 • R29 (no longer
awarded) • Other senior career
awards (K02, K06, K24, and K26).
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NIH K99/R00 AwardsNIH K99/R00 Awards
NIH K99/R00• Transition award (postdoc-to asst. professor)• Up to 5 years• Up to 2 yr mentored phase ($90K/yr + 8% F&A
costs)• Awardee becomes asst. professor• Up to 3 yr independent R phase ($249K/yr +
50% F&As)
NIH K99/R00• Transition award (postdoc-to asst. professor)• Up to 5 years• Up to 2 yr mentored phase ($90K/yr + 8% F&A
costs)• Awardee becomes asst. professor• Up to 3 yr independent R phase ($249K/yr +
50% F&As)
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NIAID “All About Grants Tutorial” Website
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Websites– http://www.niaid.nih.gov/ncn/grants/int– http://grants1.nih.gov/grants/
choosing_fundInstrument.doc– http://www.hhs.gov/grants/index.shtml
Websites– http://www.niaid.nih.gov/ncn/grants/int– http://grants1.nih.gov/grants/
choosing_fundInstrument.doc– http://www.hhs.gov/grants/index.shtml
For More InformationFor More Information