neuro med7® topical anesthetic review
TRANSCRIPT
NeuroMed7®
Rapid-onset Topical Anesthetic (Lidocaine HCl 4%)
A time saving & cost effective solution
Peak onset begins 15 – 20 minutes after application
Background
Clinicians are increasingly using topical
anesthetics to decrease the pain
associated with minimally invasive
dermatologic, aesthetic, injection,
cannulation and laser procedures (among
others).
Numerous lidocaine-containing products
are available, but comprehensive studies
are lacking regarding their relative safety
and appropriate dermatologic uses.
Concept
Lidocaine-containing products play an
integral role in cutaneous anesthesia by
providing patient comfort with minimal side
effects. Careful attention must be paid to
the particular anatomic location, the total
surface area covered, active ingredient
concentration and the duration of
anesthetic skin contact.
Awareness
Topical anesthetics decrease pain during
superficial cutaneous procedures. As the
number of in-office dermatologic
procedures continues to grow, clinicians
will benefit from awareness of the
indications, pharmacologic mechanisms,
appropriate methods of application, and
safety profiles of the currently available
prescription and over-the-counter (OTC)
topical anesthetics.
Mechanism of Action
Once inside the dermis, ester and amide
anesthetics possess the same mechanism
of action. The anesthetic binds the voltage-
gated sodium ion channel of the free nerve
endings and blocks sodium influx. The
blockade of sodium influx inhibits nerve cell
depolarization and prevents propagation of
nerve cell impulses along the nerve. Meechan
JG. Intraoral topical anesthesia. Periodontal 2000 2008;46:6 - 79
NeuroMed7® OTC Rapid Onset
Topical Anesthetic can be used
for:
• Superficial aesthetic procedures
• Hair and tattoo removal
• Minimally invasive excisions
• Injections
• Cannulation procedures
• Other minimally invasive procedures
and uses as directed by a licensed
physician
Proprietary formulation
• Designed to improve absorption
• Rapid-onset of action – 15 – 20 minutes
• Medium duration of efficacy –
approximately 60 minutes
• Safe and effective
• Patent-pending
Designed to improve absorption
• Rapid-onset – 15 to 20 minutes
• Medium duration – 60 minutes
• Safe and effective
• Easy to apply and remove
• Free of oily or gritty residue
A time saving & cost effective solution
• Save time - peak onset of action – 15 –
20 minutes
• Save money – only $23 per 2.2 ounce
(63 gram) tube – as low as $19 per tube
for bulk orders
• Increase practice revenue – can be
dispensed as a retail item for clinician-
directed, patient self-application – at
high margins
• Increase efficiency– reduced onset of
action time can increase patient flow
efficiency
Proper application
• Clean treatment area with mild cleanser and
damp, clean cloth to remove any dirt, make-
up or other material that may impede
absorption.
• Use approximately a “US quarter
dollar”(or one packet) size amount per
4”x4” area 15 - 20 minutes prior to
procedure (recommended dose – 0.75 –
2.0 grams – or milliliters – per 1”X1”
square area
• Dosage will depend on the skin type,
aggressiveness of procedure, known
patient pain tolerance and surface area.
• Use the least amount of product necessary
to achieve the required amount of local
anesthesia
Proper application – cont’d
• Avoid use on open wounds, broken skin, eyes, ears, in the nostrils andmouth
• With a gloved hand, evenly distribute the cream and rub vigorously in acircular motion for at least 30 – 60 seconds to each area of the treatment surface
• Apply more aggressively to known pain-sensitive “hot spot” areas on the face and body
• The peak action begins in approximately 15 – 20 minutes
Proper application – cont’d
• Some clinicians use an occlusivedressing for an improved efficacy –occlusion should be determined by alicensed physician.
• It is important to note that applying a hot or warm compress to the treatment area prior to application of NeuroMed7® will increase cutaneous absorption. While this method will enhance the effect of the anesthetic, special care should be exercised in recognition of the potential for increased systemic entry of the active ingredient, lidocaine HCL 4%
• Do not exceed 10 grams (milliliters) per application
• Physician should take into account total anesthetic dose when using this product in combination with other anesthetic products
Contact Sambria
Pharmaceuticals or your local
representative
1075 Peachtree Street NE, Suite 3650
Atlanta, Georgia 30309
888.246.6601 | [email protected] |
www.sambriapharma.com
THANK YOU!