neuroimaging of reading

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Dr. Tony Herdman Michael Smith Scholar Assistant Professor Department of Psychology, SFU Neuroimaging of Reading Supported by: Michael Smith Foundation for Health Research

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Michael Smith Foundation for Health Research. Neuroimaging of Reading. Dr. Tony Herdman Michael Smith Scholar Assistant Professor Department of Psychology, SFU. Supported by:. Overview. Brain Networks Models of Reading and Language Orthographic Processing Letter-Speech Integration. - PowerPoint PPT Presentation

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A love affair with MEG?

Dr. Tony HerdmanMichael Smith ScholarAssistant ProfessorDepartment of Psychology, SFUNeuroimaging of ReadingSupported by:

Michael Smith Foundation forHealth ResearchOverviewBrain Networks Models of Reading and LanguageOrthographic ProcessingLetter-Speech Integration

Networks

OrthographyPhonologySemanticsMotor PlanSpeech Generation

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Classical Reading & Language ModelMotorSpeech GenerationSemanticsPhonologyOrthography

Motor

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Classical Reading & Language Model

MEGBrain Reponses ~ 100-300 femtoTesla (10-15)Earths magnetic field ~ 30-60 microTesla (10-3)

Word ReadingCARSOUPSHOEPENBALLKEY

Speech (Generation)

Sight(orthography)Word ReadingRepeatGenerate(Herdman et al., Cerebral Cortex, 2007)MEG

Sound(phonology)Speech (Generation)

Sight(orthography)Speech ProcessingRepeatGenerate(Herdman et al., Cerebral Cortex, 2007)MEG

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Classical Reading & Language ModelMotorSpeech GenerationSemanticsPhonologyOrthography

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To the uneducated, an A is just three sticks.Winnie the PoohOrthography

To the uneducated, an A is just three sticks.Winnie the PoohOrthographyModel of Reading

(Dehaene, et al., TICS, 2005)inputAPseudoletter ?Letter: A

KAZModel of Reading

Letter Perception Study

Children (12-13 years old)

P1N1

Letter

Psuedoletter7 ms(Herdman et al., submitted)EEGNeural Networks

Neural Networks

PesudoletterLetterinputAPseudoletter ?Letter: A

KAZModel of Reading

Letter-Sound Pair Learning

Letter-Sound Pair Learning

PhonologyOrthography

Letter-Sound Pair Learning

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MotorSpeech GenerationSemanticsPhonologyOrthographyReading Impaired Brain

(Herdman et al., submitted)Reading Impaired BrainMEGBrain performs complex functions in many different regionsLearning modifies brain to make it more efficientReading impairment can be caused by one or more disruptions in the reading networkFindings support a holistic approach to learning and interventionSummaryGene ExpressionCollaborativefor Kids Only

GECKOProject

[email protected]

Experience &BehaviourNeuralSystemCell &SynapseGene &Transcription

GECKOProjectGene ExpressionCollaborativefor Kids Only

[email protected]

GECKOProjectGene ExpressionCollaborativefor Kids Only

[email protected] by:

Michael Smith Foundation forHealth ResearchThank You for Your Attention

Normal Reading Children RhymingDyslexic Reading Children Rhyming Before InterventionDyslexic Reading Children Increase After Intervention(Temple et al., PNAS, 2003)Fast ForWordReading Impaired Brain