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    Neurologic TraumaNeurologic Trauma

    Bryan E. Bledsoe, DO, FACEPBryan E. Bledsoe, DO, FACEP

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    Neurologic TraumaNeurologic Trauma

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    Neurologic TraumaNeurologic Trauma

    Suppose you were anidiot. And suppose you

    were a member ofCongress.

    But I repeat myself.

    Mark Twain

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    Traumatic Brain n!ury "TB #Traumatic Brain n!ury "TB #

    De$ined as a %low or !olt to t&e &ead or a'enetrating &eadin!ury t&at disru'tst&e $unction o$ t&e%rain.

    De$ined as a %low or !olt to t&e &ead or a'enetrating &eadin!ury t&at disru'tst&e $unction o$ t&e%rain.

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    (tatistics(tatistics

    ).* million 'eo'lesustain a TB eac& year

    in t&e +nited (tates- , die,/0-, are &os'itali1ed,

    ).) million are treatedand released $rom t&eED.

    ).* million 'eo'lesustain a TB eac& year

    in t&e +nited (tates- , die,/0-, are &os'itali1ed,

    ).) million are treatedand released $rom t&eED.

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    (tatistics(tatistics

    CausesFalls "/23#

    M4Cs "/ 3#(truck %y5against e6ents ")73#Assaults "))3#

    Blasts are t&e leading cause o$ TB $or acti6eduty military 'ersonnel in war 1ones.

    CausesFalls "/23#

    M4Cs "/ 3#(truck %y5against e6ents ")73#Assaults "))3#

    Blasts are t&e leading cause o$ TB $or acti6eduty military 'ersonnel in war 1ones.

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    (tatistics(tatisticsMales are a%out ).-times more likely tosustain a TB as a$emale.

    Males are a%out ).-times more likely tosustain a TB as a$emale.

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    (tatistics(tatistics

    8ig&est risk $or TB9* years

    )-9)7 years

    A$rican Americans&a6e t&e &ig&estdeat& rate $rom TB .

    8ig&est risk $or TB9* years

    )-9)7 years

    A$rican Americans&a6e t&e &ig&estdeat& rate $rom TB .

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    (tatistics(tatistics

    Estimated :; %illionlost $rom TB "medicalcosts and lost'roducti6ity#.uent ty'e o$ TB

    Most common in(u%$rontal corte?Frontal lo%eTem'oral lo%e

    Occi'ital "less common#O$ten associated wit& (A8.

    Cere%ral contusionMost $re>uent ty'e o$ TB

    Most common in(u%$rontal corte?Frontal lo%eTem'oral lo%e

    Occi'ital "less common#O$ten associated wit& (A8.

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    Trauma Ty'esTrauma Ty'es

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    ContusionContusion

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    Trauma Ty'esTrauma Ty'es

    (u%arac&noid&emorr&age

    Disru'tion o$su%arac&noid 6essels.)50 o$ all 'atients wit&moderate to se6ere TB

    &a6e traumatic (A8.

    (u%arac&noid&emorr&age

    Disru'tion o$su%arac&noid 6essels.)50 o$ all 'atients wit&moderate to se6ere TB

    &a6e traumatic (A8.

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    Trauma Ty'esTrauma Ty'es

    E'idural &ematomaCollection o$ %lood %etween t&e dura and t&eskull.Arterial %leed.

    ncidence.-9). 3 o$ all &ead9in!ured 'atients.

    H) 3 o$ &ead9in!ured 'atients w&o are comatose.Almost all associated wit& skull $racture.2 3 will 'rogress to uncal &erniation.

    E'idural &ematomaCollection o$ %lood %etween t&e dura and t&eskull.Arterial %leed.

    ncidence.-9). 3 o$ all &ead9in!ured 'atients.

    H) 3 o$ &ead9in!ured 'atients w&o are comatose.Almost all associated wit& skull $racture.2 3 will 'rogress to uncal &erniation.

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    E'idural 8ematomaE'idural 8ematoma

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    E'idural 8ematomaE'idural 8ematoma

    (igns and (ym'tomsClassis syndrome "H/ 3 o$ cases#

    mmediate =OC.Patient awakens and &as a Llucid inter6al.=oses consciousness as &ematoma e?'ands.

    Most commonly

    Most 'atients eit&er ne6er lose consciousness orne6er regain consciousness.

    (igns and (ym'tomsClassis syndrome "H/ 3 o$ cases#

    mmediate =OC.Patient awakens and &as a Llucid inter6al.=oses consciousness as &ematoma e?'ands.

    Most commonly

    Most 'atients eit&er ne6er lose consciousness orne6er regain consciousness.

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    Trauma Ty'esTrauma Ty'es

    (u%dural &ematomaCollection o$ %lood%etween t&e dura andt&e (AM.4enous %leed.Associated wit&

    sudden accelerationand5or deceleration.Tears %ridging 6eins.

    (u%dural &ematomaCollection o$ %lood%etween t&e dura andt&e (AM.4enous %leed.Associated wit&

    sudden accelerationand5or deceleration.Tears %ridging 6eins.

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    (u%dural 8ematoma(u%dural 8ematoma

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    (u%dural 8ematoma(u%dural 8ematoma

    +sually more %rain 'arenc&ymal in!uryt&an e'idurals.

    Classi$ied asAcute "H 0 days#(u%acute "09)* days#C&ronic "I )* days#

    +sually more %rain 'arenc&ymal in!uryt&an e'idurals.

    Classi$ied asAcute "H 0 days#(u%acute "09)* days#C&ronic "I )* days#

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    Trauma Ty'esTrauma Ty'es

    Di$$use A?onal n!ury "DA #nterru'tion o$ a?onal $i%ers in t&e w&ite

    matter and %rain stem.(&earing $orces "usually deceleration# causein!ury.

    Adults M4Cs

    Ba%ies L(&aken %a%y syndromen!ury occurs immediately and is usually

    irre6ersi%le.

    Di$$use A?onal n!ury "DA #nterru'tion o$ a?onal $i%ers in t&e w&ite

    matter and %rain stem.(&earing $orces "usually deceleration# causein!ury.

    Adults M4Cs

    Ba%ies L(&aken %a%y syndromen!ury occurs immediately and is usually

    irre6ersi%le.

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    Di$$use A?onal n!uryDi$$use A?onal n!ury

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    Trauma Ty'esTrauma Ty'es

    ntracere%ral8emorr&age

    +sually caused %ys&earing $orces.(e6erity de'ends u'onlocation and si1e.

    (econdary in!urycommon.

    ntracere%ral8emorr&age

    +sually caused %ys&earing $orces.(e6erity de'ends u'onlocation and si1e.

    (econdary in!urycommon.

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    Trauma Ty'esTrauma Ty'es

    Pro%a%ly mortal.Pro%a%ly mortal.

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    TB (igns and (ym'tomsTB (igns and (ym'toms

    An?iety5ner6ousnessBe&a6ioral c&anges

    Disin&i%itionm'ulsi6enessna''ro'riate laug&ter rrita%ility

    Di'lo'iaDe'ressionTrou%le concentrating

    An?iety5ner6ousnessBe&a6ioral c&anges

    Disin&i%itionm'ulsi6enessna''ro'riate laug&ter rrita%ility

    Di'lo'iaDe'ressionTrou%le concentrating

    A'&asiaDys'&agiaDi11iness8eadac&e+ncoordination o$mo6ements

    =ig&t&eadednessAta?iaAmnesia

    A'&asiaDys'&agiaDi11iness8eadac&e+ncoordination o$mo6ements

    =ig&t&eadednessAta?iaAmnesia

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    TB (igns and (ym'tomsTB (igns and (ym'toms

    Musclesti$$ness5s'asm(ei1ures(lee' disorders(lurred or sloweds'eec&

    TinglingNum%nessPain

    Musclesti$$ness5s'asm(ei1ures(lee' disorders(lurred or sloweds'eec&

    TinglingNum%nessPain

    4ertigo=ocali1ed weaknessNausea4omitingBody tem'eraturec&anges

    ComaPosturingPu'illary a%normality

    4ertigo=ocali1ed weaknessNausea4omitingBody tem'eraturec&anges

    ComaPosturingPu'illary a%normality

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    TB (igns and (ym'tomsTB (igns and (ym'toms

    ( N( AND ( MPTOM(

    N TBA E E T EME=

    4A AB=E

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    Assessment5TreatmentAssessment5Treatment

    Airway "wit& c9s'ine control#

    Breat&ingCirculationDisa%ility

    E?'osure

    Airway "wit& c9s'ine control#

    Breat&ingCirculationDisa%ility

    E?'osure

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    Assessment5TreatmentAssessment5Treatment

    Pal'ate skull, $acial %ones and neckAssess rate, de't& and >uality o$

    res'irations.Consider tac&y'nea at t&e $ollowing rates asign o$ deterioration

    n$ant * %reat&s 'er minute

    C&ild 0 %reat&s 'er minuteAdult / %reat&s 'er minute

    Pal'ate skull, $acial %ones and neckAssess rate, de't& and >uality o$

    res'irations.Consider tac&y'nea at t&e $ollowing rates asign o$ deterioration

    n$ant * %reat&s 'er minute

    C&ild 0 %reat&s 'er minuteAdult / %reat&s 'er minute

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    Assessment5TreatmentAssessment5Treatment

    Assess 'u'ils care$ullyPu'il si1e

    (ymmetryeacti6ity to lig&t

    Assess 'u'ils care$ullyPu'il si1e(ymmetry

    eacti6ity to lig&t

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    Assessment5TreatmentAssessment5Treatment

    Pu'illary assessmentBilateral symmetry "asymmetric 'u'ils di$$ermore t&an ) mm#.

    eacti6ity to lig&t "a $i?ed 'u'il s&ows H)mmc&ange in res'onse to %rig&t lig&t#.Dilation "greater t&an or e>ual to *mm

    diameter in adults#

    Pu'illary assessmentBilateral symmetry "asymmetric 'u'ils di$$er more t&an ) mm#.

    eacti6ity to lig&t "a $i?ed 'u'il s&ows H)mmc&ange in res'onse to %rig&t lig&t#.Dilation "greater t&an or e>ual to *mm

    diameter in adults#

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    Assessment5TreatmentAssessment5Treatment

    (ingle $i?ed and dilated 'u'il*-3 'oor outcome

    Bilateral $i?ed and dilated 'u'ils2/3 'oor outcome

    (ingle $i?ed and dilated 'u'il*-3 'oor outcome

    Bilateral $i?ed and dilated 'u'ils2/3 'oor outcome

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    Assessment5TreatmentAssessment5Treatment

    Mid9'osition $i?ed anddilated 'u'il

    (uggests %rain stem

    &erniation.ndicati6e o$ mass on

    same side.Treat &y'o?ia and

    &y'otension, i$ 'resent.Treat increased CP 'er'ractice 'arameters.

    Mid9'osition $i?ed anddilated 'u'il

    (uggests %rain stem

    &erniation.ndicati6e o$ mass on

    same side.Treat &y'o?ia and

    &y'otension, i$ 'resent.Treat increased CP 'er'ractice 'arameters.

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    Assessment5TreatmentAssessment5Treatment

    ndications o$ &erniation+nilateral or %ilateral dilated, nonreacti6e'u'ils.Asymmetric 'u'ils.Decere%rate 'osturing.No motor res'onse to 'ain$ul stimuli.

    ndications o$ &erniation+nilateral or %ilateral dilated, nonreacti6e'u'ils.Asymmetric 'u'ils.Decere%rate 'osturing.No motor res'onse to 'ain$ul stimuli.

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    Assessment5TreatmentAssessment5Treatment

    Monitor ('O / and ETCO / .Maintain ('O / I 7 3

    Maintain ETCO / %etween 0-90@ mm 8gnitiate 4 line wit& salineMaintain adult systolic BP I 7 mm 8g

    Pediatric 6alues are lower.+tili1e lasgow Coma (cale

    Monitor ('O / and ETCO / .Maintain ('O / I 7 3

    Maintain ETCO / %etween 0-90@ mm 8gnitiate 4 line wit& salineMaintain adult systolic BP I 7 mm 8g

    Pediatric 6alues are lower.+tili1e lasgow Coma (cale

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    lasgow Coma (cale "Adult#lasgow Coma (cale "Adult#

    Eye O'ening "E# 4er%al es'onse "4# Motor es'onse "M#O !"# $6

    Or&!'(!) $5 Lo*al&+!# $5

    S,o'(a'!o-# $4 Co'.-#!) $4 /&( )ra # $4

    R!a*(&o' (o S,!!* $3 I'a,,ro,r&a(! /or)# $3 D!*or(&*a(! $3

    R!a*(&o' (o a&' $2 I'*om,r! !'#& l!So-')# $2

    D!*!r! ra(! $2

    No R!#,o'#! $1 No R!#,o'#! $1 No R!#,o'#! $1

    O AL E M

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    lasgow Coma (cale " n$ant#lasgow Coma (cale " n$ant#

    Eye O'ening "E# 4er%al es'onse "4# Motor es'onse "M#O !"# $6

    Coo# Ba l!# $5 Lo*al&+!# $5

    S,o'(a'!o-# $4 Irr&(a l! Cr" $4 /&( )ra # $4

    R!a*(&o' (o S,!!* $3 Cr&!# (o a&' $3 D!*or(&*a(! $3

    R!a*(&o' (o a&' $2 Ma'# r-'(# $2 D!*!r! ra(! $2

    No R!#,o'#! $1 No R!#,o'#! $1 No R!#,o'#! $1

    O AL E M

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    Assessment5TreatmentAssessment5Treatment

    Assess %loodglucose le6el.Assess %loodglucose le6el.

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    Treat AirwayTreat Airway

    Protect C9s'ine alignment, consider$acial trauma.

    Airway su''ort 'er sco'e o$ 'ractice.ntu%ate se6ere TB 'atients.Correct &y'o?ia.

    Protect C9s'ine alignment, consider$acial trauma.

    Airway su''ort 'er sco'e o$ 'ractice.ntu%ate se6ere TB 'atients.Correct &y'o?ia.

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    J&en to ntu%ateJ&en to ntu%ate

    C( H 7 "se6ereTB #.

    All 'atients wit&res'iratory $ailure o$a'nea.

    C( H 7 "se6ereTB #.

    All 'atients wit&res'iratory $ailure o$a'nea.

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    Treat Breat&ingTreat Breat&ing

    O?ygenation.Administer su''lemental o?ygen %y non9re%reat&er or B4M as a''ro'riate.

    4entilation.Assess rate, de't&, >uality, to determine t&ee$$ecti6eness o$ res'irations.As necessary, assist 6entilations wit& B4Mand su''lemental O / .

    O?ygenation.Administer su''lemental o?ygen %y non9re%reat&er or B4M as a''ro'riate.

    4entilation.Assess rate, de't&, >uality, to determine t&ee$$ecti6eness o$ res'irations.

    As necessary, assist 6entilations wit& B4Mand su''lemental O / .

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    Treat Breat&ingTreat Breat&ing

    Adult normal4entilation rate

    ) 9)/ 'er minute

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    8y'er6entilation8y'er6entilation

    8y'er6entilationa'id PaCO /

    Cere%ral 6asoconstrictionDecreased CBF CP

    But, &y'er6entilation can CBF to t&e'oint o$ isc&emia.Monitor ETCO / Q

    8y'er6entilationa'id PaCO /

    Cere%ral 6asoconstrictionDecreased CBF CP

    But, &y'er6entilation can CBF to t&e'oint o$ isc&emia.Monitor ETCO / Q

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    8y'er6entilation8y'er6entilation

    Potential &arm in 'atients wit&oute6idence o$ %rain &erniation.

    (&ort9term measure used in s'eci$ic TB'atients "&erniation# until de$initi6ediagnostic or t&era'eutic can %e'ro6ided.

    Potential &arm in 'atients wit&oute6idence o$ %rain &erniation.

    (&ort9term measure used in s'eci$ic TB'atients "&erniation# until de$initi6ediagnostic or t&era'eutic can %e'ro6ided.

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    8y'er6entilation8y'er6entilation

    atesAges 79Adult / %reat&s 'er minute

    "ETCO / K 0- mm 8g#.

    Ages )92 years 0 %reat&s 'er minute"ETCO / K 0/90- mm 8g#.

    Ages H ) year * %reat&s 'er minute"ETCO / K 0/90- mm 8g#.

    atesAges 79Adult / %reat&s 'er minute

    "ETCO / K 0- mm 8g#.

    Ages )92 years 0 %reat&s 'er minute"ETCO / K 0/90- mm 8g#.

    Ages H ) year * %reat&s 'er minute"ETCO / K 0/90- mm 8g#.

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    FluidsFluids

    Fluids to maintain (BPI 7 mm 8g.Normal saline8y'ertonic saline

    Fluids to maintain (BPI 7 mm 8g.Normal saline8y'ertonic saline

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    Brain9Targeted T&era'iesBrain9Targeted T&era'ies

    lucose $or &y'oglycemia(edati6es $or agitation

    Analgesics $or 'ainParalytics $or ET intu%ationContro6ersial

    Mannitol=idocaine8y'ertonic (aline

    lucose $or &y'oglycemia(edati6es $or agitationAnalgesics $or 'ainParalytics $or ET intu%ationContro6ersial

    Mannitol=idocaine8y'ertonic (aline

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    DestinationsDestinations

    Mild " C( )*9)-# Emergency De'artmentModerate " C( 79)0# Trauma Center

    (e6ere " C( H 7# Trauma Center wit&se6ere TB management ca'a%ilities.

    Mild " C( )*9)-# Emergency De'artmentModerate " C( 79)0# Trauma Center

    (e6ere " C( H 7# Trauma Center wit&se6ere TB management ca'a%ilities.

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    Take 8ome MessagesTake 8ome Messages

    Clinical 'ractice s&ould %e e6idence9%ased.

    Do early and re'eated neurologicalassessments.denti$y 'atients wit& se6ere TB " C( H

    7#.

    Clinical 'ractice s&ould %e e6idence9%ased.

    Do early and re'eated neurologicalassessments.denti$y 'atients wit& se6ere TB " C( H

    7#.

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    Take 8ome MessagesTake 8ome Messages

    A6oid &y'o?ia, kee' ('O / I 7 3.A6oid &y'otension, kee' (BP I 7 mm

    8g.8y'er6entilate only $or clinical signs o$&erniation.

    Triage and trans'ort TB to a''ro'riate$acilities %ased on se6erity.

    A6oid &y'o?ia, kee' ('O / I 7 3.A6oid &y'otension, kee' (BP I 7 mm

    8g.8y'er6entilate only $or clinical signs o$&erniation.

    Triage and trans'ort TB to a''ro'riate$acilities %ased on se6erity.

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    T&e FutureT&e Future

    T&era'ies to 'rotect against secondaryin!ury

    8y'ot&ermia.(edati6e9induced coma.Meta%olic t&era'ies.Antio?idant t&era'ies.

    T&era'ies to 'rotect against secondaryin!ury

    8y'ot&ermia.(edati6e9induced coma.Meta%olic t&era'ies.Antio?idant t&era'ies.