New Faculty Orientation

August 13, 2015Overview of ResearchJennifer K. Lodge

Vice Chancellor for ResearchAssociate Dean for Research

Professor of Molecular Microbiology

MissionWashington University School of Medicine will lead in advancing human health through the best clinical care, innovative research and the education of tomorrow’s leaders in biomedicine in a culture that supports diversity, inclusion, critical thinking and creativity. Cultivate excellence and collegiality within an inclusive community Attract and develop a diverse, talented, academic workforce Lead the revolution in biomedicine Enhance our intellectual and technological environment to foster exceptionally

creative research and education Develop and maintain excellent clinical programs to provide outstanding care Observe the highest standards of ethics, integrity and compassionate care Apply advances in research and medicine to the betterment of the human

condition locally and globally

Research Activity Award Dollars (000’s) by School

FY11 FY12 FY13 FY14 FY15

Admin & Other $1,623 $2,416 $2,425 $4,463 $6,925

Arts & Sciences $33,482 $40,578 $43,033 $35,165 $35,236

Engineering $23,284 $23,220 $24,686 $27,913 $27,390

Medicine $545,158 $536,444 $462,507 $449,297 $531,177

Social Work $14,099 $17,750 $16,045 $14,872 $11,852

http://research.wustl.edu/about/AnnualReport/Pages/default.aspx

FY 15 Research Award Funding ($000’s)

to WUSM by Sponsor Type

$396,245

$25,654

$13,620$22,670

$72,734 Federal

Other Gov't

Industry

Founda on

Nonprofit

Disease AreasCancer Cardiovascular, Diabetes and Obesity

Neurosciences, Brain Disorders and Mental Health

Women’s and Children’s Health

Microbes, Infections and Immunity

Transformational Initiatives“Big Data”: Driving Discovery with Information

Bringing Discovery to Prevention and Cure

Developmental and Regenerative Biology

Genomic Medicine and Molecular Phenotyping

Imaging: Molecules to Man

Therapeutics and Diagnostics Development

School of Medicine: Plan for Excellence10-year Strategic Plan, 2008; Updated August 2012

Areas of Emphasis

So you want to do research?

Developing Projects

Understanding compliance

Setting up your program or lab

Finding, Obtaining and managing funding

Faculty Expectations

Each individual conducting research must uphold the highest standards of ethical and professional conduct

Tools and services to help meet that expectation: Policies and Procedures Education Programs and Communication Tools Grant and Contract Services Compliance Oversight

Leadership, Support, Service to WUSTL Promote and support WUSTL investigators

Conduct of world-class research Sharing results through publication and

commercialization for public use & benefit

Elements Operations Policy Compliance Strategy Research Development Ethics/Integrity/Education

http://research.wustl.edu

Visit the OVCR Website

http://research.wustl.edu/Pages/default.aspx

Research Gateway

One stop for all research resources

Common Sign-on (WUSTL Key)

https://research.wustl.edu/Pages/ResearchGateway.aspx

Research GetawayPersonalized Menu

An interactive web-based questionnaire designed to identify the various compliance and educational activities you need to complete.

http://complianceprofile.wustl.edu/

Faculty Compliance Profile

http://research.wustl.edu/COMPLIANCEAREAS/RCR/Pages/default.aspxhttp://research.wustl.edu/Resources/PERCSS/Pages/PERCSS.aspx

Research Integrity & Scientific Misconduct

Research Integrity Policy http://research.wustl.edu/PoliciesGuidelines/Documents/ResearchIntegrityPolicy2010Revisions.pdf

Policy for Authorship on Scientific and Scholarly Publications

http://www.wustl.edu/policies/authorship.html

Responsible Conduct of Research at WUSTL

Program for the Ethical and Responsible Conduct of Science and Scholarship (PERCSS)

Reporting Concerns: Who do I talk to?

Several ways to report concerns: – choose one that works for you

Talk to PI … if you are comfortable; it could be a misunderstanding

Talk to Division or Department head… if you are comfortable

Research Compliance Office: Denise McCartney (747-6253)

VCR: Jennifer Lodge (747-0515) University Compliance Office

Anonymous help line: 362-4998Web

Tools & Services to Help You

Identify Potential Sponsors Find external and internal funding sources:

http://research.wustl.edu/PGC/Pages/IdentifyingFunding.aspx

Funding Coordinator : langton@wustl.edu Private Funding Sources:

http://privatefundingsources.wustl.edu Internal Competitions:

http://internalcompetitions.wustl.edu Award and Contract Negotiation and

Management Office of Sponsored Research Services Other Compliance Office

(see contact info in Research Compliance Guide) Center for Clinical Studies (Industry sponsored

clinical trials )

Internal awards/seed fundingPrivate funding resources Corporate and foundation relations

Customized funding searches

Resources for research funding

http://research.wustl.edu/PGC/Funding/Pages/Funding.aspx

http://research.wustl.edu/Cores/Pages/default.aspx

Resources for research information

Research News is an opt-in listserv to keep the WUSTL research community informed about current topics and issues related to research administration, management, compliance, and grant announcementshttp://research.wustl.edu/researchnews

Other Agency Listservs:NIHDept. of HealthUSDAVAEtc….

Pilot funding for your projects

Usually announced through Research News

• Bear Cub – up to $75K for commercialization

• URSA program – up to $25K for interdisciplinary projects

• Many centers and institutes offer pilot or seed funding.

Helping you find fundingMonthly email for private funding sources

Pat Gregory, Corporate and Foundation Relations

Internal Selections

• When we can only submit a limited number of applications to a funding agency or program

• A new process was fully implemented in 2015 (Susan Dutcher, Genetics and Erik Herzog, Biology)• Transparency• Informational sessions• Streamlined applications• Mentorship

Helping you find fundingWeekly email for limited competitions

Facilities & Administrative Costs(a.k.a. Indirect or Overhead)

Definition: Costs incurred for common or joint objectives which cannot be specifically identified with a particular project. These are real costs for the institution!

Applied as a percentage of direct costs Federal grants: F&A 52.5% mtdc=on-campus research). WUSTL rates set by

WUSTL negotiation with federal govt, are standard for NIH grants, and are public information

Foundations: Up-front charge. Rates often set by the foundation, may/may not be negotiated by WUSTL by school, WUSTL rate may/may not be public information

Industry: Up-front charge. Rates set by WUSTL by school, WUSTL rate is not public information

THM: Indirects are Complicated! THM: For Non-NIH grants, it is best for faculty to NOT discuss Indirect rates with

sponsors. Leave this to OSRS!! Please!!!!

Facilities & Administrative Costs

NIH Negotiated Rate AdministrativeGeneral AdministrationDepartmental Administration 26.0% (cap)Sponsored Administration

FacilitiesDepreciation - Buildings & Improv. 6.5Depreciation - Moveable Equip. 2.9Interest 1.4 26.5%Operations & Maintenance 13.6Library 1.6

52.5%

What do F&A dollars pay for?

Facilities Heat, Light & A/C Building maintenance Building depreciation Interest on building loans/bonds Equipment depreciation Library

Administrative Presidents, VP’s and Dean’s Offices Human Resources Payroll, Purchasing, etc Research Administration & Accounting Department Administration IRB, ASC, regulatory

How is F&A calculated?

Each party comes to a potential collaboration with different expectations, organizational cultures, motivations, and experiences

Differences in academic vs industry missions and environments must be navigated to establish a successful relationship

Academic-Industry Collaborations

Core academic mission: Education, creation and dissemination of knowledge, outreach

Core industry mission: Create value for investors, provide useful goods and services, expand the state of

the art in a product or service Successful external collaborations must provide compelling benefits and return on

investment in exchange for funding

Mike Kinch, Associate Vice Chancellor and Director, Center for Research Innovation in Business, WUSTL

•For the PI who is new to collaborations with industry partners.

•Lays the foundation for productive institutional-industrial collaboration by providing an overview of differing organizational environments and by discussing issues unique to such research collaborations•For the industrial PI who is new to collaborating with academic institutions.

•Lays the foundation for productive institutional-industrial collaboration by providing an overview of differing organizational environments and by discussing issues unique to such research collaborations

Academic-Industry Collaborations

http://sites.nationalacademies.org/PGA/uidp/PGA_055253

Fundamental expansion of WUSTL academic & research culture

From a culture of: • predominantly federal research funding• primary valued output (“exit strategy”) for new knowledge is publication in high

quality research journals

To a culture of Innovation and Entrepreneurship:• Multiple & diverse sources of highly valued research funding• Multiple valued, non-exclusive outputs (“exit strategies”) for new knowledge,

including IP property creation, protection and commercialization, in addition to publication in high quality research journals

WUSTL RESEARCH INNOVATION & ENTREPRENEURSHIP

Holden Thorp, Provost

Innovation & Discovery

Traditional Knowledge Path

Knowledge & Entrepreneurship Path

Innovation & Discovery

IP create & protect

Commerciali-zation

Innovation, intellectual property, commercialization and entrepreneurship at Washington University

WUSTL I & E cultural

expansion

Dedric Carter, Assoc VC, Innovation & Entrepreneurship

There is a role for academia in commercializable innovation and creating intellectual property.

Such activity is compatible with the traditional (WUSTL) academic mission.

Innovation, intellectual property, commercialization and entrepreneurship at Washington University

Emre Toker, Director, Skandelaris Center, WUSTL

Innovate VMS

WUSTL Innovation Ecosystem

INDUSTRY

Visit the OTM Website

http://research.wustl.edu/Offices_Committees/OTM/Pages/OTM.aspx

Entrepreneurship

Commercialization

IP: create, protect, license

DiscoveryInnovation/Maturation

OTM MissionTo promote the public utilization of University innovations

created by faculty and employees through the formation and management of commercial partnerships

I & E Mission

Capital: Translational, seed, venture

http://research.wustl.edu/Offices_Committees/OTM/Pages/OTM.aspx

WUSTL IP Commercialization Success Total revenue received by WU over 15 yrs is $113M:

School share = $53M PI share = $49M OTM share = $7M Other 3rd Parties = $4M

14 PIs have generated > $1.0M revenue Dr. Jack Ladenson’s (WUSM) IP has generated >$50M Ladenson chosen as inaugural recipient (2010) of WUSTL

Chancellor’s Award for Innovation and Entrepreneurship Faculty start-ups – 13 in four (4) years

See who can help you get started

GrantsTeri Medley

Office of Sponsored Research Services

Joe Gindhart

Assistant Vice Chancellor for Animal Affairs

Chair, Animal Studies Committee

Dana R. Abendschein, PhD

Research Education/Information

Blake R. Fuhler

Research Ethics & Compliance OfficeJeneane K. Braden

Human Research QA Program

Mary T. Clarke

Vice Chancellor for ResearchJennifer Lodge, PhD

Associate Vice Chancellor for

Research AdministrationDenise A. McCartney

Assistant Vice Chancellor forVeterinary Affairs

Director, Div. of Comparative Medicine

Steven L. Leary, DVM

Director of FacilitiesComparative Medicine

William (Chip) Keys

Executive AssistantAleatha Harris

Funding Support Catherine Determan

Export Control Laura Langton

Joint Research Office for Contracts

Melanie Roewe, JD

Updated 8/2015

Office of the Vice Chancellor for Research

Office of the Vice Chancellor for Research

Sponsored Projects

Accounting

Vice Chancellor for Finance and CFO

Barb FeinerCenter for Clinical

StudiesYi Zhang

OVCR: RESEARCH ADMINISTRATION ORGANIZATIONAL SUMMARYOVCR: RESEARCH ADMINISTRATION ORGANIZATIONAL SUMMARY

Nick MangnallTechnology Coordinator747-1453

@4240 Duncan

Nick MangnallTechnology Coordinator747-1453

@4240 Duncan

Last updated 8.10.2015

Blake FuhlerManager Research

Education & Information747-2941

4240 Duncan

Blake FuhlerManager Research

Education & Information747-2941

4240 Duncan

Teri MedleyDirector, Grants

747.4444 4240 Duncan

Teri MedleyDirector, Grants

747.4444 4240 Duncan

Jeneane BradenManager Research

Ethics & Compliance Office

747-41524240 Duncan

Jeneane BradenManager Research

Ethics & Compliance Office

747-41524240 Duncan

Melanie RoeweExecutive Director,

Joint Research Office of Contracts (JROC)

747-5390@4240 Duncan

Melanie RoeweExecutive Director,

Joint Research Office of Contracts (JROC)

747-5390@4240 Duncan

Joe GindhartInterim Associate Vice Chancellor for

Research AdminstrationOffice of Sponsored Research Services

(OSRS)&

Sponsored Projects Accounting (reports through Finance)

935-7089North Campus

Joe GindhartInterim Associate Vice Chancellor for

Research AdminstrationOffice of Sponsored Research Services

(OSRS)&

Sponsored Projects Accounting (reports through Finance)

935-7089North Campus

ESCROESCRO

CRICRI

COICOI

Denise McCartneyAssociate Vice Chancellor for Research Administration

747.6253@4240 Duncan

Denise McCartneyAssociate Vice Chancellor for Research Administration

747.6253@4240 Duncan

Mickey ClarkeManager Human Research Quality

Assurance Program 747-5526

4240 Duncan

Mickey ClarkeManager Human Research Quality

Assurance Program 747-5526

4240 Duncan

Laura LangtonExport Control

Manager 747-1378@4240 Duncan

Laura LangtonExport Control

Manager 747-1378@4240 Duncan

Catherine DetermanFunding Resources

747-1378@4240 Duncan

Catherine DetermanFunding Resources

747-1378@4240 Duncan

ASCASC

Questions?