New Generations

Year 10, Pathway C

2012

Outcomes

Identify genetic disorders from too many/ too few body and sex chromosomes

Explain how genetic disorders occur

Genetic Disorders

There are three ways to be born with a genetic disorder:

1. Too many/not enough sex chromosomes

2. Too many body chromosomes 3. Mutation of genes

A normal karyotype

Genetic Disorders

Too many sex chromosomes: Klinefelter’s syndrome (male) Triplo X syndrome (female)

Extra X chromosome Infertility

XXY or XXX

Klinefelter’s Karyotype

Genetic Disorders

Too few sex chromosomes : Turner’s syndrome

Only one sex chromosome (X) Short stature Webbed neck

Turner Syndrome Karyotype

Genetic Disorders

Too many body chromosomes results in down syndrome 47 chromosomes instead of 46 Impairment of learning ability Minor physical abnormalities

Down syndrom karyotype

Genetic Disorders

What causes these?

Let’s investigate

Genetic Disorders

Genetic disorder are caused by mistakes made during meiosis

Genetic Disorders – The cause

Outcomes

Identify genetic disorders from too many/ too few body and sex chromosomes

Explain how genetic disorders occur