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Issue:ORN-2017-25_______________________________________________________________________________________________________________NJIT Research Newsletter includes recent awards, and announcements of research relatedseminars,webinars, national and federal researchnews related to research funding, andGrantOpportunity Alerts. The Newsletter is posted on the NJIT Research Websitehttp://www.njit.edu/research/.

SpecialAnnouncements:Page1GrantOpportunityAlerts:KeywordIndex:Page2RecentAwards:Page3 IntheNews(Relatedtoresearchfunding):Page5WebinarsandEvents:Page8 GrantOpportunities:Page9IRB/IBCMeetingSchedule:Page32StreamlyneUpdate:Page33

SpecialAnnouncement

InternalCompetitionforNSFInnovationsinGraduateEducation(IGE)Program

Pre-proposals in the following format (maximum 5 pages) should be submitted to respectivedean’s office by September August 25, 2017. Deans are requested to forward up to 2 pre-proposals with their recommendations to the Office of Research at dhawan@njit.edu bySeptember4,2017.Twopre-proposalswillbeselectedafterinstitutionalreviewbySept8,2017.Pre-proposalFormat(maximum5pages):

1. Titleandkeypersonnelwithaffiliation2. ProjectSummary(1-page)3. InternalandExternalCollaboration4. IntellectualMerit:InnovationinGraduateEducation5. BroaderImpact6. PerformanceAssessment/ProjectEvaluation7. TentativeBudgetSummaryandAnyResourcesNeeded

GrantProgram:InnovationsinGraduateEducation(IGE)ProgramAgency:NationalScienceFoundationNSF17-585RFPWebsite:https://www.nsf.gov/pubs/2017/nsf17585/nsf17585.htmBriefDescription:TheInnovationsinGraduateEducation(IGE)programisdesignedtoencouragethedevelopmentand implementationofbold,new,andpotentially transformativeapproaches toSTEMgraduateeducation training.Theprogramseeksproposals that exploreways forgraduatestudents in research-based master's and doctoral degree programs to develop the skills,knowledge,andcompetenciesneededtopursuearangeofSTEMcareers.

IGEfocusesonprojectsaimedatpiloting,testing,andvalidatinginnovativeandpotentiallytransformative approaches to graduate education. IGE projects are intended to generate theknowledgerequiredfortheircustomization,implementation,andbroaderadoption.Theprogramsupports testing of novel models or activities with high potential to enrich and extend theknowledgebaseoneffectivegraduateeducationapproaches.

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Theprogramaddressesbothworkforcedevelopment,emphasizingbroadparticipation,andinstitutional capacity building needs in graduate education. Strategic collaborations with theprivate sector, non-governmental organizations (NGOs), government agencies, nationallaboratories, fieldstations, teachingand learningcenters, informalsciencecenters,andacademicpartnersareencouraged.Awards:StandardGrants.AnticipatedFundingAmount:$4,000,000LimitonNumberofProposalsperOrganization:2AneligibleorganizationmayparticipateintwoInnovationsinGraduateEducationproposalspercompetition.Participationincludesservingasaleadorganizationonanon-collaborativeproposalor as a lead organization, non-lead organization, or subawardee on a collaborativeproposal.Organizations participating solely as evaluators on projects are excluded from thislimitation. Proposals that exceed the institutional eligibility limit (beyond the first twosubmissionsbasedontimestamp)willbereturnedwithoutreviewregardlessoftheinstitution'srole(lead,non-lead,subawardee)inthereturnedproposal..LimitonNumberofProposalsperPIorCo-PI:1An individual may serve as Lead Principal Investigator (PI) or Co-PI on only one proposalsubmitted to the IGE program per annual competition. Proposals that exceed the PI/Co-PIeligibilitylimit(beyondthefirstsubmissionbasedontimestamp)willbereturnedwithoutreviewregardlessoftheindividual'srole(PIorco-PI)inthereturnedproposal.LetterofIntent:NotRequiredProposalSubmissionDueDate:October25,2017Contacts:LauraB.Regassa,telephone:(703)292-2343,email:lregassa@nsf.gov

• TaraL.Smith,telephone:(703)292-7239,email:tsmith@nsf.gov• StephenMulkey,telephone:(703)292-8954,email:smulkey@nsf.gov

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GrantOpportunityAlerts

KeywordsandAreasIncludedintheGrantOpportunityAlertSectionBelowNSF: Innovations inGraduateEducation(IGE)Program;DiscoveryResearchPreK-12(DRK-12);CISE Research Infrastructure (CRI);Division ofMaterials Research: TopicalMaterials ResearchPrograms(DMR-TMRP); Louis Stokes Alliances forMinority Participation (LSAMP); Secure andTrustworthy Cyberspace (SaTC); Advancing Informal STEM Learning (AISL); Information andIntelligentSystems(IIS)NIH:GrantProgram:Exploratory/DevelopmentalInvestigationsonPrimaryImmunodeficiencyDiseases (R21); Synthetic Biology for Engineering Applications (R01); Assay development andscreeningfordiscoveryofchemicalprobesortherapeuticagents(R01);DiscoveryofCell-basedChemicalProbesforNovelBrainTargets(R21);BRAINInitiative:NewConceptsandEarly-StageResearchforLarge-ScaleRecordingandModulationintheNervousSystem(R21);CentralNeuralMechanisms of Age-Related Hearing Loss (R01); Small Grants on Primary ImmunodeficiencyDiseases(R03)Department of Defense/US Army/DARPA/ONR: DoD, Peer Reviewed Alzheimer's Research;FY2018 Basic Research Challenge (BRC) Program; CENTER OF EXCELLENCE: Trusted Human-MachineTeaming;FY2018VannevarBushFacultyFellowshipDepartment of Energy: Advanced Manufacturing Graduate-Level Traineeships; Photovoltaics(PV)InnovationRoadmap;TechnologyDevelopmenttoEnsureEnvironmentallySustainableCO2InjectionOperations

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NASA:ROSES2017:SolarIrradianceScienceTeam;ROSES2017:NewInvestigatorProgramNationalEndowmentofHumanities:SummerStipends;ResearchandDevelopmentGrantsBayer:NovelDrugTargetsSimonFoundation:AlfredP.SloanFoundationGrants

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RecentResearchGrantandContractAwards

Congratulationstofacultyandstaffonreceivingresearchgrantandcontractawards!PI:XinDi(PI),BharatBiswal(Co-PI)andXiaoboLi(Co-PI)Department:BiomedicalEngineeringGrant/Contract Project Title:MultimodalNeuroimagingStudyofSexDifferences inPreschoolChildrenwithAutismFundingAgency:NJDepartmentofHealthDuration:07/01/16-06/30/18PI:ChaseWu(PI)Department:ComputerScienceGrant/ContractProjectTitle:IPAccessGatewayElectronicsFundingAgency:USDepartmentofEnergyDuration:02/20/17-12/31/17PI:KamaleshSirkar(PI)Department:Chemical,BiologicalandPharmaceuticalEngineeringGrant/ContractProjectTitle:NovelNanofiltrationMembranes for IsolationofPharmaceuticalCompounds FundingAgency:CompactMembraneSystems,Inc.Duration:07/01/17-06/30/18PI:GaleSpak(PI)Department:ContinuingProfessionalEducation(CPE) Grant/ContractProjectTitle:AdvancedManufacturingTalentNetworkFundingAgency:NJDeptofLaborandWorkforceDevelopmentDuration:01/01/17-12/31/17PI:GaleSpak(PI)Department:ContinuingProfessionalEducation(CPE) Grant/ContractProjectTitle:Transportation,Logistics,andDistributionTalentNetworkFundingAgency:NJDeptofLaborandWorkforceDevelopmentDuration:01/01/17-12/31/17PI:RaulMercado(PI)Department:PTACGrant/ContractProjectTitle:ProcurementTechnicalAssistanceProgram(PTAP)FundingAgency:DLA-PTAPDuration:08/01/17-07/31/18

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PI:GaleSpak(PI)Department:ContinuingProfessionalEducation(CPE) Grant/ContractProjectTitle:TechnologyTalentNetworkFundingAgency:NJDeptofLaborandWorkforceDevelopmentDuration:01/01/17-12/31/17PI:YassineBoubendir(PI)Department:MathematicalSciencesGrant/ContractProjectTitle:EfficientHighFrequencyIntegralEquationsandIterativeMethodsFundingAgency:NSFDuration:06/01/17-07/31/20PI:WenZhang(PI)Department:CivilandEnvironmentalEngineeringGrant/Contract Project Title: Removal of Polyfluoroalkyl Substances (PFASs) And OtherMicropollutants Using Spiky Sweetgum Seeds as Renewable Bioadsorbents to Support "WasteControlbyWaste"andpoint-of-use(POU)WaterTreatmentDevicesFundingAgency:USGeologicalSurveyDuration:03/30/17-02/28/18PI:BryanPfister(PI)Department:BiomedicalEngineeringGrant/ContractProjectTitle:InVitroPlatformforHighThroughputStudyofInjurytoHumanCorticalProjectionNeuronsFundingAgency:NJDepartmentofHealthDuration:07/01/16-06/30/18PI:BryanPfister(PI)Department:BiomedicalEngineeringGrant/Contract Project Title: A Therapeutic Approach to Reduce Angiotensin II InducedNeurovascularComplicationsinTraumaticBrainInjuryFundingAgency:NJDepartmentofHealthDuration:07/01/16-06/30/18PI:AbdiAli(PI)andMichaelEhrlich(Co-PI)Department:ElectricalandComputerEngineering;MTSchoolofManagementGrant/ContractProjectTitle:PFI:AIR-TT:ANovelVectorAcousticCommunicationTechnologyforHighSpeedUnderwaterModemsFundingAgency:NSFDuration:08/15/15-01/31/18PI:JorgeGolowasch(PI)andHoracioRotstein(Co-PI)Department:BiologicalSciences;MathematicalSciencesGrant/ContractProjectTitle:TheRoleofNeuronalIonicCurrentCorrelationsandLevelSetsinNetworkActivity FundingAgency:NSF Duration:08/01/17-07/31/20

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PI:HyominKim(PI)Department:CenterforSolarTerrestrialResearchGrant/ContractProjectTitle:CollaborativeResearch:GEM-GlobalPropagationCharacteristicsofElectromagneticIonCyclotronWavesFundingAgency:NSF Duration:08/01/17-07/31/20

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IntheNews…

(NationalandFederalNewsRelatedtoResearchFundingandGrantOpportunities)HouseReversesProposedCutToEnergyInnovationHubs:TheU.S.HouseofRepresentativeshasreversedcourseandhasnowdecidedtofundtheDepartmentofEnergy's(DOE’s)five"energyinnovationhubs"infiscalyear2018,whichbegins1October.TheHouseappropriationscommitteehad zeroedout funding for thehubsin theHouse versionof the so-called energy andwaterbill,whichfundsDOE.ButlastnightthefullHousepassedapackageofamendmentstothebill,whichthe House has now rolled together with three other spending bills into a so-called minibusspendingbill.Oneoftheamendments,submittedbyRepresentativeMarkTakano(D–CA),restoresthehubs,eachofwhichiscurrentlyfundedat$25millionperyearorless.TheenergyinnovationhubsarethebrainchildofStevenChu,theNobelPrize–winningphysicistwhoservedasSecretaryofEnergyfrom2009to2013.Theyinclude:

• the Joint Center for Artificial Photosynthesis at the California Institute of Technology inPasadena;

• the Consortium for Advanced Simulation of LightWater Reactors, headquartered at OakRidgeNationalLaboratoryinTennessee;

• the Joint Center for Energy Storage Research at ArgonneNational Laboratory in Lemont,Illinois;

• theCriticalMaterialsInstituteatAmesLaboratoryinIowa;and• ayet-to-besitedhubonlow-energydesalinationofseawater,whichreceiveditsfirstfunds

thisyear.Thechange to theHouseversionofDOE'sproposedbudgetdoesn’tguarantee that thehubswillsurvive.BothchambersofCongressmuststillpasstheirversionsofthebudgetandthenhammerouttheirsubstantialdifferencesonmyriadissues.TheHouse’senergyandwaterbill,forexample,wouldeliminateDOE'sAdvanceResearchProjectsAgency-Energy,whichseekstoquicklytranslatethe best ideas from basic research into new energy technologies,whereas Senate appropriatorswouldbump itsbudgetby8% to$330million.And theHousewould fundDOEOfficeofEnergyEfficiency andRenewable Energy at $1.1 billion,whereas Senate appropriatorswould fund it at$1.9 billion. More information on http://www.sciencemag.org/news/2017/07/house-reverses-proposed-cut-energy-innovation-hubsNSFFY18Budget:TheNationalScienceFoundation'scurrentbudgetwouldshrinkby2.1percent,or$162million,inthebillapprovedbySenateappropriators,JeffMervisreportsinScienceInsider.Thatnumber,andtheproposedcutof$193milliontoNASA’sScienceMissionDirectorate,drewastatement of concernfrom the Association of American Universities. "The university-basedresearch supported by these agencies has kept the United States globally competitive in many

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areas of science, technology, and innovation; these cuts imperil our ability to maintain thiscompetitiveness," AAU says. The money provided by the Commerce, Justice, and Sciencesubcommitteewouldnonetheless erasemost of theTrumpcuts atNSF, theNational InstituteofStandards and Technology (NIST), and the National Oceanic and Atmospheric Administration(NOAA). More information on http://www.sciencemag.org/news/2017/07/house-reverses-proposed-cut-energy-innovation-hubsDefense MINIBUS Bill: House Republican leaders are fine-tuning strategy on a spending bill“minibus” that theyplantoput toavoteby theAugustrecess,which isexpectedtocontain fourappropriationsmeasures and items fromothers.HouseGOP leadersplan in the comingweek tobringupaso-calledminibus(seetext)containing:the$658billionFY2018Defensespendingbill;the$37.5Energy-Watermeasure;the$88.8billionMilitaryConstructionandVeteransAffairsbill;and the $3.58 Legislative Branch bill. More on the website https://www.bna.com/defense-minibus-readied-n73014461999/SpaceTechnologyBoost:WhilecuttingNASAScience,Senateappropriatorsprovide$700millionforthespaceagency'stechnologyprograms-adding$13.5millionto2017levels.Amongprioritiesareunmannedaerialsystems,whichget$5million"toconductfurtherresearchinabroadrangeofpublic safety applications over land and maritime environments" at Federal AviationAdministration centers of excellence. Senators also provide current levels of support to NASA'seducationprogram,whichtheadministrationhadproposedtoslash.CleanEnergyandFusion:TheCommitteerecommends$167.5millionforsolar;$72.5millionforwind;and$82millionforwaterpower.Contrarytotheadministration'sshifttoearly-stageR&D,itsays "such an approach will not successfully integrate the results of early-stage research anddevelopment into the U.S. energy system." The panel says it "understands the Department haseitherdelayedordoesnot intendto initiatearenewal fortheBatteriesandEnergyStorageHub,the JointCenter forEnergy StorageResearch [JCESR].TheCommitteedirects theDepartment tomove forwardwith the reviewandrenewalprocess to support thenext5-year charter fornext-generationbatteryandstoragetechnologies"andprovides$24millionforthehub.Whileproviding$232 million for fusion, the panel seeks once again to zero out America's contribution to theInternational Thermonuclear Experimental Reactor being built in France. With House support,ITER has survived in the past. The committee calls on DOE to identify strategic laboratory,university,andindustrypartnershipsthatwouldenhancenationalsecurityandassist industryinaddressing critical threats, including electromagnetic pulse, geomagnetic disturbances, cyber-attacks, and supply chain disruptions. The panel "continues to encourage the Department toestablishuniversitypartnershipstosupportongoingfossilenergyprograms, topromotebroaderresearch intoCCS technologies, and to expand its technology transfer efforts."More informationonhttps://www.congress.gov/115/crpt/srpt125/CRPT-115srpt125.pdfNext Generation Researchers Initiative: NIH has launched the Next Generation ResearchersInitiative tobolstersupport forearly-stageandmid-career investigators toaddress longstandingchallengesfacedbyresearcherstryingtoembarkuponandsustainindependentresearchcareers.NIH and its stakeholder community have for many years been concerned about the long-termstabilityofthebiomedicalresearchenterprise.Toomanyresearchersvyingfor limitedresourceshas led to a hypercompetitive environment. Many highlymeritorious applications go unfunded.This has too often resulted in misaligned incentives and unintended consequences for talented

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researchers at all career stages who are trying to succeed and stay in science. The currentenvironmentisparticularlychallengingformanynew-andmid-careerinvestigators.

Over the last several years, NIH has taken numerous steps to balance, strengthen, andstabilizethebiomedicalresearchworkforce.

• Specialcouncilreviewpolicy• NewInvestigator/EarlyStageInvestigatorPolicies• InitiativesfromtheAdvisoryCounciltotheNIHDirector• Programsforearly-stageinvestigators• Newfundingmechanismsforsustainedresearchfunding(R35)

To ensure the long-termstability and strengthof theU.S. biomedical researchenterprise,thepoolofNIH-fundedresearchersmustbebalancedsuchthatthegreatestnumberofearlystageandmid-careerresearchersareenabledtotackletoughresearchquestionstoimprovethehealthofallAmericans.This conclusion iswidely sharedbothwithinandoutsideofNIH. In fact, the21stCenturyCuresAct,whichbecamelawinDecemberof2016,instructstheNIHDirectortopromotepolicies that will encourage earlier independence and increased funding for new investigators.Moreinformationonthewebsitehttps://grants.nih.gov/ngri.htmAPowerPointpresentationfromthe advisory council is posted on the websitehttps://acd.od.nih.gov/documents/presentations/06082017Tabak.pdfNSF Policy and Awards Update (May 2017): NSF Pilots a New Collaborator and OtherAffiliationsTemplate:LastmonthNSFbeganpilotinganewformatforsubmittingCollaboratorsandOtherAffiliationsInformationinFastLane.Proposersarerequiredtoincludecollaboratorsandother affiliations information for principal investigators (PIs), co-PIs and other senior projectpersonnel. NSF uses this information to manage reviewer selection. The pilot standardizes thecollection of this data across the Foundation and ensures that the information is submitted in asearchableformat.ThisreducestheburdenonNSFprogramstaffwhocurrentlymustspendtimemanipulating non-searchable files. Likewise, for the community, proposers can rest assuredknowing that their format is acceptable to NSF. The new format requires PIs, co-PIs and othersenior project personnel who are identified on the proposal to individually upload theirCollaboratorsandOtherAffiliationsInformationasaSingleCopyDocumentwhichareonlyseenbyNSFstaffandnotbyreviewers.

ProposerswillbedirectedtothenewspreadsheettemplatewhileinFastLane.Thetemplateis fillable, and the content and format requirementsmust not be altered by the user. ProposersshouldnotconvertthefiletoPDFformatpriortosubmittingtheproposaltoNSF,ratheritshouldbe completed and saved in .xlsx or .xls format to ensure preservation of searchable text, anduploaded into FastLane as a Single Copy Document. Using any other file format may delay thetimely processing and review of the proposal. The template has been tested inMicrosoft Excel,Google Sheets and LibreOffice. In addition to benefiting themerit review process, this templateprovides a compliant and reusable format for PIs tomaintain andupdate for use in subsequentproposal submissions toNSF. The newCollaborators andOther Affiliations pilot only applies toFastLane proposal submissions. Grants.gov proposal submissions shall continue to follow theinstructions in the Grants.gov Application Guide, Chapter VI. 2.4. More information onhttps://www.nsf.gov/pubs/2017/nsf17084/nsf17084.pdf?WT.mc_id=USNSF_109

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WebinarandEventsEvent: IEEE Tech Insider Webinar: How Analytics can be used to Drive More EffectiveBusinessDecisionsaroundAdditiveManufacturingWhen:August15,2017;2.00PMWebsite:http://spectrum.ieee.org/webinar/how-analytics-can-be-used-to-drive-more-effective-business-decisions-around-additive-manufacturingAbout the Webinar: The digitalization journey continues. From our foundation presentation“HowDigitalization is transforming theElectronics Industry”,we continue along the connectedjourneytoadoptingadigitalizationstrategy.ManufacturersareincreasinglylookingtodisruptivetechnologieslikeAdditiveManufacturingtoenableondemandproduction,producecomponentsnever before possible and reduce order to cash cycle time. Even though 3D Printers aremoreaccessible thanever,moving fromprototypingtomeaningfulvolumeproductionstillrequiresasignificant investment in capital, process change and retooling of personnel. Going beyond thebasic technology of 3D printing, this session draws from recent collaboration between leadingmanufactureswhoareseekingtofullyunderstandthe“why”toadditivemanufacturingandhowdata analytics can be used to drive more effective business decisions. We believe a new dataanalytics approach to unify, contextualize and present simplified business insights for propercomponent/partselectionhasthepotentialtodramaticallyimprovethereturnfrom3Dprinting.Allbyfocusingvaluablecapitalresourcestoproducetherightpartsattherighttime.Pleasejoinus while we take a deeper dive into some of the new and fascinating areas and technologicaladvancesthataretransformingtheelectronicsindustry.Speaker:JeffSpencerisaPortfolioDevelopmentExecutiveatSiemenswithover22yearsofindustryexperienceinBigDataAnalytics,3DDesignandProductLifecycleManagement.Registerat:AboveURL.Event: IEEE Tech Insider Webinar: Low Current / Ultra-High Resistance MeasurementFundamentalsWhen:August10,2017;1.00PMWebsite:https://event.on24.com/eventRegistration/EventLobbyServlet?target=reg20.jsp&referrer=&eventid=1463381&sessionid=1&key=0E6BDE38E441621A6CDA92B4F8716264&regTag=&sourcepage=registerAbouttheWebinar:Performingcurrentvs.voltagecharacterizationondevicesandmaterialsatverylowcurrent levelspresentsauniquesetofmeasurementchallenges.Normalmeasurementissues such as noise, transient signals and cabling and fixturing parasitics aremuch harder tosolvewhendealingwithcurrentsinthefemtoamprange.Inaddition,manycutting-edgematerialshaveextremelyhighresistancesthatconventionalDMMsandsource/measurementunits(SMUs)cannotmeasure. In this seminarKeysightwill explain themeasurement techniques, tricks andtoolsnecessarytomeasurecurrentsdownto0.01femtoampsandresistancesupto10PetaOhmswithbothhighmeasurementconfidenceandrepeatability.Speaker:AlanWadsworth,MarketingBrandManager,KeysightRegisterat:AboveURL.Event:IEEEWebinar:AdvancedDataAcquisitionandLoggingSystemsWhen:AvailableonDemandWebsite:https://event.on24.com/eventRegistration/EventLobbyServlet?target=reg20.jsp&utm_source=Te

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ch%2BAlert&utm_medium=Email&utm_campaign=TechAlert_07-06-17&eventid=1433462&sessionid=1&key=9BF06E3E1B2B31C7FAE1E9C5CF16298A&regTag=&sourcepage=registerAbouttheWebinar:Itisdifficulttoenvisionanindustrialautomationapplicationthatdoesnotincludeadataacquisitionsystem.Mostapplications includesensordata thatmustbeacquired,analyzed, and logged, using acquisition (DAQ) systems that can be as diverse as the sensorsthemselves.Withtheriseof theInternetofThings,DAQrequirementsarebecomingevenmorestrict,bringingnewchallenges.Today’sdataacquisitionsystemsshouldperformanalysisinrealtime,workwith large amounts of analogdata, andmakedecisionsbasedon those results. Theimportanceofarobust,real-time,decision-making,signal-processingsystemFPGAplatformsthebest fit for many such applications. Designers of DAQ systems need to consider scalability,portability, and stable operation. At this session,wewill explore themain challenges and bestpractices indata-loggingsystemdesign,particularly in theLabVIEWenvironment.Thewebinarexamines the underlying implementation of an object-oriented approach to application design,DAQ tips and tricks for FPGA platforms, and an object-oriented programming architecture forreal-timeandhostapplications.ThesessionalsoexploresseveralcasestudiesofdevelopedDAQsystems,showingthemainchallengesfacedandthesolutionsimplementedintheprojects.Registerat:AboveURL.

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GrantOpportunitiesNationalScienceFoundationGrantProgram:InnovationsinGraduateEducation(IGE)ProgramAgency:NationalScienceFoundationNSF17-585RFPWebsite:https://www.nsf.gov/pubs/2017/nsf17585/nsf17585.htmBriefDescription:TheInnovationsinGraduateEducation(IGE)programisdesignedtoencouragethedevelopmentand implementationofbold,new,andpotentially transformativeapproachestoSTEMgraduateeducation training.Theprogramseeksproposals that exploreways forgraduatestudents in research-based master's and doctoral degree programs to develop the skills,knowledge,andcompetenciesneededtopursuearangeofSTEMcareers.

IGEfocusesonprojectsaimedatpiloting,testing,andvalidatinginnovativeandpotentiallytransformative approaches to graduate education. IGE projects are intended to generate theknowledgerequiredfortheircustomization,implementation,andbroaderadoption.Theprogramsupports testing of novel models or activities with high potential to enrich and extend theknowledgebaseoneffectivegraduateeducationapproaches.

Theprogramaddressesbothworkforcedevelopment,emphasizingbroadparticipation,andinstitutional capacity building needs in graduate education. Strategic collaborations with theprivate sector, non-governmental organizations (NGOs), government agencies, nationallaboratories, fieldstations, teachingand learningcenters, informalsciencecenters,andacademicpartnersareencouraged.Awards:StandardGrants.AnticipatedFundingAmount:$4,000,000LimitonNumberofProposalsperOrganization:2AneligibleorganizationmayparticipateintwoInnovationsinGraduateEducationproposalspercompetition.Participationincludesservingasaleadorganizationonanon-collaborativeproposalor as a lead organization, non-lead organization, or subawardee on a collaborativeproposal.Organizations participating solely as evaluators on projects are excluded from this

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limitation. Proposals that exceed the institutional eligibility limit (beyond the first twosubmissionsbasedontimestamp)willbereturnedwithoutreviewregardlessoftheinstitution'srole(lead,non-lead,subawardee)inthereturnedproposal..LimitonNumberofProposalsperPIorCo-PI:1An individual may serve as Lead Principal Investigator (PI) or Co-PI on only one proposalsubmitted to the IGE program per annual competition. Proposals that exceed the PI/Co-PIeligibilitylimit(beyondthefirstsubmissionbasedontimestamp)willbereturnedwithoutreviewregardlessoftheindividual'srole(PIorco-PI)inthereturnedproposal.Internal Competition for Limited Submission: Pre-proposals in the following format(maximum 5 pages) should be submitted to respective dean’s office by September August 25,2017.Deansarerequestedtoforwardupto2pre-proposalswiththeirrecommendationstotheOfficeofResearchatdhawan@njit.edubySeptember4,2017.Twopre-proposalswillbeselectedafterinstitutionalreviewbySeptember8,2017.Pre-proposalFormat(maximum5pages):

8. Titleandkeypersonnelwithaffiliation9. ProjectSummary(1-page)10. InternalandExternalCollaboration11. IntellectualMerit:InnovationinGraduateEducation12. BroaderImpact13. PerformanceAssessment/ProjectEvaluation14. TentativeBudgetSummaryandAnyResourcesNeeded

LetterofIntent:NotRequiredProposalSubmissionDueDate:October25,2017Contacts:LauraB.Regassa,telephone:(703)292-2343,email:lregassa@nsf.gov

• TaraL.Smith,telephone:(703)292-7239,email:tsmith@nsf.gov• StephenMulkey,telephone:(703)292-8954,email:smulkey@nsf.gov

________________________________________________________________________________________GrantProgram:DiscoveryResearchPreK-12(DRK-12)Agency:NationalScienceFoundationNSF17-584RFPWebsite:https://www.nsf.gov/pubs/2017/nsf17584/nsf17584.htmBrief Description: The Discovery Research PreK-12 program (DRK-12) seeks to significantlyenhancethelearningandteachingofscience,technology,engineering,mathematicsandcomputerscience (STEM) by preK-12 students and teachers, through research and development of STEMeducation innovations and approaches. Projects in the DRK-12 program build on fundamentalresearch inSTEMeducationandpriorresearchanddevelopmentefforts thatprovide theoreticalandempirical justificationforproposedprojects.Projectsshouldresult inresearch-informedandfield-testedoutcomesandproductsthatinformteachingandlearning.Teachersandstudentswhoparticipate in DRK-12 studies are expected to enhance their understanding and use of STEMcontent,practicesandskills.

TheDRK-12program invitesproposals that address immediate challenges that are facingpreK-12 STEM education as well as those that anticipate radically different structures andfunctions of preK-12 teaching and learning. TheDRK-12 programhas threemajor research anddevelopmentstrands:(1)Assessment;(2)Learning;and(3)Teaching.Theprogramrecognizesthesynergyamongthethreestrandsandthatthereissomeoverlapandinterdependenceamongthem.However,proposalsshouldidentifyaclearfocusoftheproposedresearchefforts(i.e.,assessment,learning,orteaching)consistentwiththeproposal'smainobjectivesandresearchquestions.Theprogramsupportsfivetypesofprojects:(1)Exploratory,(2)DesignandDevelopment,(3)Impact,

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(4)ImplementationandImprovement,and(5)ConferencesandSyntheses.AllfivetypesofprojectsapplytoeachofthethreeDRK-12programstrands.Awards:StandardGrants.AnticipatedFundingAmount:$57,000,000LetterofIntent:NotRequiredProposalSubmissionDueDate:November14,2017Contacts:Inquiriescanbemadeto,telephone:(703)292-8620,email:DRLDRK12@nsf.gov

• DavidB.Campbell,telephone:(703)292-5093,email:dcampbel@nsf.gov• JuliaV.Clark,telephone:(703)292-5119,email:jclark@nsf.gov• CatherineEberbach,telephone:(703)292-4960,email:ceberbac@nsf.gov

________________________________________________________________________________________GrantProgram:CISEResearchInfrastructure(CRI)Agency:NationalScienceFoundationNSF17-581RFPWebsite:https://www.nsf.gov/pubs/2017/nsf17581/nsf17581.htmBriefDescription:TheCISEResearchInfrastructure(CRI)programdrivesdiscoveryandlearninginthecoreCISEdisciplinesofthethreeparticipatingCISEdivisionsbysupportingthecreationandenhancementofworld-classresearchinfrastructurethatwillsupportfocusedresearchagendasincomputer and information science and engineering. This infrastructure will enable CISEresearchers to advance the frontiers of CISE research. Further, through the CRI program, CISEseekstoensurethatindividualsfromadiverserangeofacademicinstitutions,includingminority-servingandpredominantlyundergraduateinstitutions,haveaccesstosuchinfrastructure.TheCRIprogramsupportstwoclassesofawards:

• Institutional Infrastructure (II)awards support the creation ofnew (II-NEW)CISEresearch infrastructure or theenhancement (II-EN)of existing CISE researchinfrastructure to enable world-class CISE research opportunities at the awardee andcollaboratinginstitutions.

• Community Infrastructure (CI)awards support theplanning (CI-P)for new CISEcommunity research infrastructure, thecreation of new (CI-NEW) CISE researchinfrastructure, theenhancement (CI-EN) of existing CISE infrastructure, orthesustainment (CI-SUSTAIN) of existing CISE community infrastructureto enableworld-classCISEresearchopportunities forbroad-basedcommunitiesofCISEresearchersthatextendwellbeyondtheawardeeinstitutions.EachCIawardmaysupporttheoperationof such infrastructure, ensuring that theawardee institution(s) is (are)wellpositioned toprovide a high quality of service to CISE community researchers expected to use theinfrastructuretorealizetheirresearchgoals.

Awards:StandardGrants.AnticipatedFundingAmount:$18,000,000LetterofIntent:NotRequiredLimitonNumberofProposalsperOrganization:A university or organization may submit no more than three Institutional Infrastructure (II)proposals per competition. There is no limit on Community Infrastructure (CI) proposals percompetition.These eligibility constraints will be strictly enforced in order to treat everyone fairly andconsistently.Intheeventthataninstitutionororganizationexceedsthislimit,proposalsreceivedwithinthelimitwillbeacceptedbasedontheearliestdateandtimeofproposalsubmission(i.e.,thefirstthreeIIproposalsreceivedwillbeacceptedandtheremainderwillbereturnedwithoutreview).Noexceptionswillbemade.

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InternalLOI:Ifyouareinterestedinsubmittingaproposal,pleasesendaprojectsummarywithIntellectualMerit andBroader Impact to theOffice ofResearch at dhawan@njit.edu as soon aspossiblebutnolaterthanOctober1,2017toensurecomplianceoflimitedsubmission.LimitonNumberofProposalsperPIorCo-PI:2In each annual competition, an individualmay participate in atmost two proposals, across allclasses,asPI,Co-PI,orSeniorPersonnel.These eligibility constraints will be strictly enforced in order to treat everyone fairly andconsistently.Intheeventthatanindividualexceedsthislimit,proposalsreceivedwithinthelimitwill be accepted based on the earliest date and time of proposal submission (i.e., the first twoproposals received will be accepted and the remainder will be returned without review).Noexceptionswillbemade.ProposalSubmissionDueDate:November2,2017Contacts: Harriet G. Taylor, Lead Program Director, 1175, telephone:(703) 292-8950,email:htaylor@nsf.gov

• TaoLi,ProgramDirector,CCF,1115,telephone:(703)292-8238,email:taoli@nsf.gov• Mimi McClure, Associate Program Director, CNS, 1145, telephone:(703) 292-8950,

email:mmcclure@nsf.gov• Wendy Nilsen, Program Director, IIS, 1125, telephone:(703) 292-2568,

email:wnilsen@nsf.gov________________________________________________________________________________________Grant Program: Division of Materials Research: Topical Materials Research Programs(DMR-TMRP)Agency:NationalScienceFoundationNSF17-580RFPWebsite:https://www.nsf.gov/pubs/2017/nsf17580/nsf17580.htmBrief Description:Research supportedby theDivisionofMaterialsResearch (DMR) focusesonadvancing fundamental understanding of materials, materials discovery, design, synthesis,characterization,properties,andmaterials-relatedphenomena.DMRawardsenableunderstandingof the electronic, atomic, and molecular structures, mechanisms, and processes that governnanoscaletomacroscalemorphologyandproperties;manipulationandcontroloftheseproperties;discoveryofemergingphenomenaofmatterandmaterials;andcreationofnoveldesign,synthesis,andprocessingstrategiesthatleadtonewmaterialswithuniquecharacteristics.Thesediscoveriesand advancements transcend traditional scientific and engineering disciplines. The Divisionsupports research and education activities in the United States through funding of individualinvestigators, teams, centers, facilities, and instrumentation. Projects supported by DMR areessential for the development of future technologies and industries thatmeet societal needs, aswellpreparationofthenextgenerationofmaterialsresearchers.

ThissolicitationappliestothefollowingsixDMRTopicalMaterialsResearchProgramsthatfund researchandeducationalprojectsby individual investigatorsor small groups:Biomaterials(BMAT), CondensedMatter Physics (CMP), Electronic andPhotonicMaterials (EPM),Metals andMetallicNanostructures(MMN),Polymers(POL),andSolid-StateandMaterialsChemistry(SSMC).ItdoesnotapplytothefollowingtwoDMRTopicalMaterialsResearchPrograms,whichhavetheirown solicitations: Ceramics (CER) (NSF 16-597) and Condensed Matter and Materials Theory(CMMT)(NSF16-596).Awards:StandardGrants.AnticipatedFundingAmount:$55,000,000LetterofIntent:NotRequiredProposalSubmissionDueDate:October1,2017-November1,2017

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Contacts: Joseph A. Akkara, Biomaterials (BMAT), telephone: (703) 292-4946,email:jakkara@nsf.gov

• Aleksandr L. Simonian, Biomaterials (BMAT), telephone: (703) 292-2191,email:asimonia@nsf.gov

• Tomasz Durakiewicz, Condensed Matter Physics (CMP), telephone: (703) 292-4892,email:tdurakie@nsf.gov

• Paul E. Sokol, Condensed Matter Physics (CMP), telephone: (703) 292-8436,email:psokol@nsf.gov

________________________________________________________________________________________GrantProgram:LouisStokesAlliancesforMinorityParticipation(LSAMP)Agency:NationalScienceFoundationNSF17-579RFPWebsite:https://www.nsf.gov/pubs/2017/nsf17579/nsf17579.htmBriefDescription:TheLouisStokesAlliances forMinorityParticipation(LSAMP)programisanalliance-basedprogram.Theprogram'stheoryisbasedontheTintomodelforstudentretention1.The overall goal of the program is to assist universities and colleges in diversifying thenation'sscience,technology,engineeringandmathematics(STEM)workforcebyincreasingthenumberofSTEMbaccalaureateandgraduatedegreesawardedtopopulationshistoricallyunderrepresentedin these disciplines: African Americans, Hispanic Americans, American Indians, Alaska Natives,Native Hawaiians, and Native Pacific Islanders. The LSAMP program takes a comprehensiveapproach to student development and retention. Particular emphasis is placed on transformingundergraduate STEM education through innovative, evidence-based recruitment and retentionstrategies,andrelevanteducationalexperiencesinsupportofracialandethnicgroupshistoricallyunderrepresentedinSTEMdisciplines.

TheLSAMPprogramalsosupportsknowledgegeneration,knowledgeutilization,programimpactanddisseminationtypeactivities.Theprogramseeksnewlearningandimmediatediffusionof scholarly research into the field. Under this program, funding for STEM educational andbroadening participation research activities could include research to develop new models inSTEMengagement,recruitmentandretentionpracticesforallcriticalpathwaystoSTEMcareersorresearch on interventions such as mentoring, successful learning practices and environments,STEMefficacystudies,andtechnologyuse.

Overall, theLSAMPprogramprovides fundingtoalliancesthat implementcomprehensive,evidence-based, innovative, and sustained strategies that ultimately result in the graduation ofwell-prepared,highly-qualifiedstudentsfrom.Awards:StandardGrants.AnticipatedFundingAmount:$22,300,000LetterofIntent:NotRequiredProposalSubmissionDueDate:November03,2017FirstFridayinNovember,AnnuallyThereafterBridgetotheDoctorate(BD)ActivityNovember17,2017ThirdFridayinNovember,AnnuallyThereafterNewandRenewalLSAMPPre-AlliancePlanning,BridgetotheBaccalaureate(B2B),STEMPathwaysImplementation-OnlyProjectsJanuary26,2018STEMPathwaysandResearchAlliancesJanuary26,2018LastFridayinJanuary,AnnuallyThereafter

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LouisStokesRegionalCentersofExcellenceinBroadeningParticipationNovember16,2018ThirdFridayinNovember,AnnuallyThereafterSTEMPathwaysandResearchAlliancesContacts: LSAMP Program Team, telephone: (703) 292-8640, fax: (703) 292-9018,email:LSAMP_national@nsf.gov

• A. James Hicks, Co-Lead/Program Director, 815 N, telephone: (703) 292-4668,email:ahicks@nsf.gov

• Martha L. James, Co-Lead/Program Director, telephone: (703) 292-7772,email:mjames@nsf.gov

________________________________________________________________________________________GrantProgram:SecureandTrustworthyCyberspace(SaTC)Agency:NationalScienceFoundationNSF17-576RFPWebsite:https://www.nsf.gov/pubs/2017/nsf17576/nsf17576.htmBrief Description: In today's increasingly networked, distributed, and asynchronous world,cybersecurity involves hardware, software, networks, data, people, and integration with thephysicalworld.However,society'soverwhelmingrelianceonthiscomplexcyberspacehasexposeditsfragilityandvulnerabilities:corporations,agencies,nationalinfrastructureandindividualshavebeen victims of cyber-attacks. Achieving a truly secure cyberspace requires addressing bothchallenging scientific and engineering problems involving many components of a system, andvulnerabilities that arise from human behaviors and choices. Examining the fundamentals ofsecurityandprivacyasamultidisciplinarysubjectcanleadtofundamentallynewwaystodesign,build and operate cyber systems, protect existing infrastructure, and motivate and educateindividualsaboutcybersecurity.ThegoalsoftheSecureandTrustworthyCyberspace(SaTC)programarealignedwiththeFederalCybersecurityResearchandDevelopmentStrategicPlan(RDSP)andtheNationalPrivacyResearchStrategy(NPRS)toprotectandpreservethegrowingsocialandeconomicbenefitsofcybersystemswhile ensuring security and privacy. The RDSP identified six areas critical to successfulcybersecurity R&D: (1) scientific foundations; (2) risk management; (3) human aspects; (4)transitioningsuccessfulresearchintopractice;(5)workforcedevelopment;and(6)enhancingtheresearch infrastructure. The NPRS, which complements the RDSP, identifies a framework forprivacy research, anchored in characterizing privacy expectations, understanding privacyviolations, engineering privacy-protecting systems, and recovering from privacy violations. Inalignmentwiththeobjectivesinbothstrategicplans,theSaTCprogramtakesaninterdisciplinary,comprehensiveandholisticapproachtocybersecurityresearch,development,andeducation,andencouragesthetransitionofpromisingresearchideasintopractice.The SaTC program welcomes proposals that address cybersecurity and privacy, and draw onexpertise in one or more of these areas: computing, communication and information sciences;engineering; economics; education; mathematics; statistics; and social and behavioralsciences.Proposals that advance the field of cybersecurity and privacy within a singledisciplineorinterdisciplinaryeffortsthatspanmultipledisciplinesarebothencouraged.Proposalsmaybesubmittedinoneofthefollowingthreeprojectsizeclasses:

• Smallprojects:upto$500,000intotalbudget,withdurationsofuptothreeyears;• Mediumprojects:$500,001to$1,200,000intotalbudget,withdurationsofuptofouryears;• Frontier projects: $5,000,000 to $10,000,000 in total budget,with durations of up to five

years.

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In addition to the project size classes, proposals must be submitted pursuant to one of thefollowing designations, each of which may have additional restrictions and administrativeobligationsasspecifiedinthisprogramsolicitation.

• CORE: This designation is the main focus of the SaTC research program, spanning theinterests of NSF's Directorates for Computer and Information Science and Engineering(CISE), Engineering (ENG), Mathematical and Physical Sciences (MPS), and Social,Behavioral and Economic Sciences (SBE). Interdisciplinary proposals are welcomed toCORE.

• EDU:TheEducation(EDU)designationwillbeusedtolabelproposalsfocusingentirelyoncybersecurityeducation.NotethatproposalsthataredesignatedasEDUhavebudgetslimitedto$300,000anddurationsofuptotwoyears.

• STARSS: The Secure, Trustworthy, Assured and Resilient Semiconductors and Systems(STARSS) designation will be used to label proposals that are submitted to the jointprogram focused on hardware security with the Semiconductor Research Corporation(SRC).The STARSS designationmay only be used for Small proposals. This designation hasadditionaladministrativeobligations.

• TTP:TheTransitiontoPractice(TTP)designationwillbeusedto labelproposals thatarefocused exclusively on transitioning existing research results to practice.The TTPdesignationmayonlybeusedforSmallandMediumproposals.

Awards:StandardGrants.AnticipatedFundingAmount:$68,000,000LetterofIntent:NotRequiredProposalSubmissionDueDate:October03,2017-October10,2017MEDIUMProjectsOctober13,2017-October20,2017FRONTIERProjectsNovember01,2017-November15,2017SMALLProjectsDecember06,2017-December13,2017CYBERSECURITYEDUCATIONProjectsContacts: Nina Amla, Program Director, CISE/CCF, 1110, telephone: (703) 292-8910,email:namla@nsf.gov

• Dan Cosley, Program Director, CISE/IIS, 1125, telephone: (703) 292-8491,email:dcosley@nsf.gov

• Sol Greenspan, Program Director, CISE/CCF, 1115, telephone: (703) 292-8910,email:sgreensp@nsf.gov

• Timothy Hodges, Program Director, MPS/DMS, 1020, telephone: (703) 292-2113,email:thodges@nsf.gov

________________________________________________________________________________________GrantProgram:AdvancingInformalSTEMLearning(AISL)Agency:NationalScienceFoundationNSF17-573RFPWebsite:https://www.nsf.gov/pubs/2017/nsf17573/nsf17573.htmBrief Description: TheAdvancing Informal STEM Learning(AISL) program seeks to advancenew approaches to and evidence-based understanding of the design and development of STEMlearning opportunities for the public in informal environments; provide multiple pathways forbroadeningaccesstoandengagementinSTEMlearningexperiences;advanceinnovativeresearch

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onandassessmentofSTEMlearningininformalenvironments;andengagethepublicofallagesinlearningSTEMininformalenvironments.

The AISL program supports six types of projects: (1) Pilots and Feasibility Studies, (2)Research in Service to Practice, (3) Innovations in Development, (4) Broad Implementation, (5)LiteratureReviews,Syntheses,orMeta-Analyses,and(6)Conferences.Awards:StandardGrants.AnticipatedFundingAmount:$33,000,000LimitonNumberofProposalsperOrganization:3

An institution or organization may serve as lead on no more than three (3) proposalssubmitted to theNovemberdeadline.However, an institutionororganizationmaypartnerasasubawardonotherproposalssubmitted.PleaseinformtheOfficeofViceProvostforResearchatdhawan@njit.edu by September 1, 2017 with a summary including Intellectual Merit andBroaderImpactsectionsifyouintendtosubmitaproposaltothissolicitation.LetterofIntent:NotRequiredProposalSubmissionDueDate:November06,2017Contacts: Address Questions to the Program, telephone: (703)292-8616,email:DRLAISL@nsf.gov________________________________________________________________________________________GrantProgram:InformationandIntelligentSystems(IIS):CoreProgramsAgency:NationalScienceFoundationNSF17-572RFPWebsite:https://www.nsf.gov/pubs/2017/nsf17572/nsf17572.htmBriefDescription:CISE'sDivisionofInformationandIntelligentSystems(IIS)supportsresearchandeducationprojectsthatdevelopnewknowledgeinthreecoreprograms:

• TheCyber-HumanSystems(CHS)program;• TheInformationIntegrationandInformatics(III)program;and• TheRobustIntelligence(RI)program.

Proposalsintheareaofcomputergraphicsandvisualizationmaybesubmittedtoanyofthethreecoreprogramsdescribedabove.Proposersareinvitedtosubmitproposalsinthreeprojectclasses,whicharedefinedasfollows:

• SmallProjects-upto$500,000totalbudgetwithdurationsuptothreeyears;• MediumProjects-$500,001to$1,200,000totalbudgetwithdurationsuptofouryears;and• LargeProjects-$1,200,001to$3,000,000totalbudgetwithdurationsuptofiveyears.

A more complete description of the three project classes can be found in SectionII. ProgramDescriptionofthisdocument.Awards:StandardGrants.AnticipatedFundingAmount:$100,000,000LetterofIntent:NotRequiredProposalSubmissionDueDate:September20,2017-September27,2017MEDIUMProjectsSeptember20,2017-September27,2017LARGEProjectsNovember01,2017-November15,2017SMALLProjectsContacts:WilliamS.Bainbridge,PointofContact,Cyber-HumanSystems(CHS),1125,telephone:(703)292-8930,email:wbainbri@nsf.gov

• JamesDonlon,Pointofcontact,RobustIntelligence(RI),1122,telephone:(703)292-8074,email:jdonlon@nsf.gov

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• EphraimP.Glinert,PointofContact,Cyber-HumanSystems(CHS),1125,telephone:(703)292-8930,email:eglinert@nsf.gov

• TatianaKorelsky,PointofContact,Robust Intelligence (RI),1125, telephone: (703)292-8930,email:tkorelsk@nsf.gov________________________________________________________________________________________________

NationalInstitutesofHealthGrantProgram:Exploratory/DevelopmentalInvestigationsonPrimaryImmunodeficiencyDiseases(R21)Agency:NationalInstitutesofHealthPAR-17-333RFPWebsite:https://grants.nih.gov/grants/guide/pa-files/PAR-17-333.htmlBrief Description: This FOA will support a wide range of innovative, exploratory and/ordevelopmental research on primary immunodeficiency diseases. Research areas supported bythisFOAinclude,butarenotlimitedto:

• Identifyingtheclinical,immunological,geneticandmolecularcharacteristicsofgeneticallydeterminedimmunodeficiencydiseases;

• Identifyingthemolecularbasisofprimaryimmunodeficiencydiseases;• Advancingourunderstandingofhowageneticvariantresultsinimmunodeficiency;• Discovering/developing improved diagnostic/newborn screening tools for primary

immunodeficiencydiseases;• Performingexvivostudieswithhumanspecimens• Discovering/developingnewanimalmodelsforprimaryimmunodeficiencydiseases;and• Analyzing clinical data and samplesmaintained in primary immunodeficiency registries,

consortium databases and repositories to address questions relevant to primaryimmunodeficiencyresearch.

OtherresearchareassupportedbythisFOAincludestudiesofnoveltherapeuticapproachesfortreatmentofprimaryimmunodeficiencydiseasesto:

• Improve and better understand existing treatments of primary immunodeficiencydiseases;

• Understandcomplicationsassociatedwithprimaryimmunodeficiencydiseases;• Define environmental or other triggers that result in complications in individuals with

primaryimmunodeficiencydiseases;and• Identifyandvalidatebiomarkersforprimaryimmunodeficiencydiseases.

ResearchareasNOTappropriateforthisFOAincludestudiesof:• Immunodeficiencyresultingfrominfection(e.g.,HIV);• Immunodeficiency resulting from treatments (e.g., chemotherapy), exposures (e.g.,

radiation),immunosuppressionfollowingtransplantation,orautoimmunedisorders;• Immunodeficiencyresultingfromagingorimmaturity;and• Basic immunologic mechanisms unless related to understanding of primary

immunodeficiencydiseases.Awards:Directcostsarelimitedto$275,000overthetwo-yearprojectperiod,withnomorethan$200,000indirectcostsallowedinanysingleyear.LetterofIntent:NotRequiredDeadline: Standarddatesapply,by5:00PMlocaltimeofapplicantorganization.Alltypesofnon-AIDSapplicationsallowedforthisfundingopportunityannouncementaredueonthesedates.Applicants are encouraged to apply early to allow adequate time to make any corrections toerrorsfoundintheapplicationduringthesubmissionprocessbytheduedate.

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_____________________________________________________________________________________________GrantProgram:SyntheticBiologyforEngineeringApplications(R01)Agency:NationalInstitutesofHealthPAR-17-334RFPWebsite:https://grants.nih.gov/grants/guide/pa-files/PAR-17-334.htmlBrief Description: One of the great challenges in biomedical research is to be able toquantitatively predict, test, and harness the complex dynamics of biological systems. Syntheticbiologyisthedesignandconstructionofnewbiologicalpartsandsystems,andthere-designofexistingandnaturalbiologicalsystemsforspecificpurposes.Incontrasttothetraditionalgeneticengineeringapproach,whichusuallyfocusesonindividualgenesandproteins,syntheticbiologyadopts amore systematic approach targeting entire pathways, networks, andwhole organismswith quantitative control andmodulation. Synthetic biology is arguably the cornerstone of thenext generation of reengineered cells. Gaining new insights into the complex and dynamicbiologicalpathwaysof thesedesigner cells anddeveloping cell-baseddiagnostics and therapiesareatthefrontiersofbiomedicalscience.Enablingthesedenovobiologicalsystemswillrequiretheability todesignandbuildcomplexpathwayswithendogenousornovel functionsandwithpredictable and quantitative responses to endogenous or environmental signals. Achieving thisparadigmwillallowthetestingofhypothesesoncomplexbiologicalsystemsandthedevelopmentof novel therapeutic strategies anddiagnostic capabilities. To improve the reach and impact ofthisparadigmonhumanhealth,anintegrativeresearchplanbasedoncollaborationsofsyntheticbiologistswithcomputational scientists, cellbiologists,engineers,and/orphysicianscientists isstronglyrecommended.SpecificAreasofResearchInterestSynthetic biology for human health is advancing, butmajor challenges, such as the inability toengineerrobustcomplexmetabolicandsignalingnetworksortoproducecellswithreliableandpredicable behavior once in the host, currently limit application. This FOA encourages thedevelopmentoftoolsandtechnologytotacklechallengesinbiomedicalresearchandincell-basedtherapiesanddiagnostics. Specific topicsof interest include,butarenot limited to, those listedbelow.

• Cell-free and cell-based systems for testing and analyzingbiological systemsand for theefficientandscalablesynthesisofcomplexbiologicalproducts

• Cell-free (prototyping genetic circuits, discovering and evolving enzymes, andconductingbiomolecularreactions)

• Cell-based (materials and pharmaceutical production,microbiome reprogramming,diagnostics)

• Natural and engineered biological circuits for implementing regulation and decision-makingstrategiesincells(modeling,analysis,design,anduseofbiologicalcircuits,cell-cellcommunication,generegulation,computationstrategies)

• Expanding biochemical functionality (novel genetic alphabets, changing molecularmachinery of the cell, constructing genomically recoded organisms, genetically encodedreporters)

• Advanced genome editing techniques for manipulating DNA (computational algorithms,zincfingernucleases,TALeffectornucleases,CRISPR-Cas9)

• Design and evolution strategies to construct biological systems (directed evolution,continuousevolution,multiplexedevolution)

NIBIBStatementofInterestTheNationalInstituteofBiomedicalImagingandBioengineering(NIBIB)isinterestedinprojectsfromalloftheaforementionedresearchareas,butwithanemphasisonsupportingthecreationof

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toolsandmethodstoenablesyntheticbiologyapproachesacrossawidespectrumofbiomedicalengineering challenges addressed through broadly applicable diagnostic, therapeutic, andinterventional technologies. Furthermore, NIBIB is interested in supporting projects that usesyntheticbiologyapproaches for thedevelopmentandvalidationof technologieswithpotentialclinicalapplications.Examplesoftechnologiesinclude,butarenotlimitedto,biomaterials,drugand gene delivery systems and devices, molecular imaging probes, immunoengineering,multiscalemodeling,sensors,microsystems,tissuechips,andtissueengineering.AcompletelistofprogrammaticinterestsinNIBIBcanbefoundat:https://www.nibib.nih.gov/research-funding.Furthermore,theNIBIBmissiondoesnotincludethedevelopmentofnewtechnologiestoaddressbasic researchquestions in cellularprocesses, functions, and structure. For research leading tothedevelopmentofsuchtechnologies,applicantsshouldconsulttheNationalInstituteofGeneralMedicalSciences(NIGMS).NCIStatementofInterestThe National Cancer Institute (NCI) supports a broad-based portfolio of cancer research anddevelopment projects encompassing basic, translational, clinical, and epidemiologicalinquiries. This includes support for the development and application of novel enablingtechnologies in a broad range of cancer research. NCI strongly encourages multidisciplinarycollaborations between synthetic biologists and cancer biologists or translational cancerresearchers in developing novel solutions to tackle critical cancer problems. Some generalexamplesthatarerelevanttothisFOAinclude,butarenotlimitedto:

• Developing novel synthetic biology methods and tools relevant to cancer research andcancermanagement

• Using synthetic biology methods to develop novel cell, tissue, and animal based modelsystemstostudythefundamentalmechanismofcancerdevelopment,progression,and/orresponsetotreatment

• Usingsyntheticbiologymethodstodevelopandevaluatenoveldiagnostic,preventive,andtherapeuticapproachesrelevanttohumancancer

NCCIHStatementofInterestNCCIHsupportsadiverseportfolioofnaturalproductsresearch.Thisincludestheuseofsystemsbiologytechnologytobetterunderstandthebiosynthesisofnaturalproducts.NCCIHencouragesapplications to this initiative aimed at elucidating biosynthetic pathways for high value, plantbased, natural products and developing ways to improve their production in either native orheterologoushosts.Inthecontextofthisinitiative,highvalue,plantbased,naturalproductsaredefinedasthosewhichhavewellestablishedtherapeuticpropertiesforhumans.Useofsystemsbiology for theengineeringandproductionof compoundswhicharenotknown fromanaturalsourceareconsideredlowpriorityforNCCIH.ExamplesofresearchofinteresttoNCCIHinclude,butarenotlimitedto:

• Use of synthetic biology tools to identify biosynthetic gene clusters or pathwaysresponsibleforthebiosynthesisofplantbasednaturalproducts

• Useofsyntheticbiologytoolstoimproveproductionofplantbasednaturalproductsfromtheirnativesources

• Useofsyntheticbiology tools toassemblebiosyntheticmachineryandoptimizeyield forplantbasednaturalproductsintoheterologoushosts

Awards:Applicationbudgetsarenotlimitedbutneedtoreflecttheactualneedsoftheproposedproject.LetterofIntent:October8,2017Deadline: Standarddatesapply,by5:00PMlocaltimeofapplicantorganization.Alltypesofnon-AIDSapplicationsallowedforthisfundingopportunityannouncementaredueonthesedates.

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Applicants are encouraged to apply early to allow adequate time to make any corrections toerrorsfoundintheapplicationduringthesubmissionprocessbytheduedate.ThisFOAisbeingissuedwithlimitedduedatestoaccommodatethetransitionfromFORMS-DtoFORMS-Eapplicationpackages.ThisFOAwillbe reissued foradditionalduedate(s)onorafterJanuary25,2018._____________________________________________________________________________________________Grant Program: Assay development and screening for discovery of chemical probes ortherapeuticagents(R01)Agency:NationalInstitutesofHealthPAR-17-438RFPWebsite:https://grants.nih.gov/grants/guide/pa-files/PAR-17-438.htmlBriefDescription:ProjectsforthisFOAmayspanuptothreestagesofdiscoveryresearch:1)assaydevelopment;2)primaryscreenimplementation;and3)hitvalidation.For applications requesting support for more than one stage, demonstration of feasibility isneeded, including strong justification and supportingpreliminarydata for the stagesproposed.AreastobeconsideredforeachstagearedescribedbelowandgiveningreaterdetailinSectionIV(ApplicationandSubmissionInformation,PHS398ResearchPlan).1.AssayDevelopmentThisFOAseekstoapplynewknowledgeandscreeningtechnologiestodevelopassaysfornoveltargetsandpathways.Projectsforassaydevelopmentshouldemphasizethedesignandvalidationofcreativeapproachestoassaybiologicalanddiseaseprocessesthathavepotentialtobeusedforchemical probe or drug discovery. Assays focusing on areas and approaches that have beenextensivelystudiedshouldbeavoidedunlessastrongrationaleisprovidedforadditionalstudiesintheprojectedarea.Targetsassociatedwithrareandneglecteddiseasesareencouraged.ProposedprimaryscreeningassaysshouldberelevanttothescopeoftheresearchwithinatleastoneoftheparticipatingNIHICsfocusingonspecificdiseasesoronrelevantbasicphysiology,cellbiology,ordevelopmentalprocessesthatprovideinsightintoadisease.2.PrimaryScreenImplementationApplicants are encouraged to collaboratewith an experienced screening facility, particularly ifhigh throughput screening (HTS) is planned.The screening facilitymayprovide advice such asidentificationandselectionofcommercialHTSassayreagents,andsuitableHTSassayformatandreadout.Inaddition,thescreeningfacilitymaybeabletoprovideassistanceinadaptingassaystoanHTSformat(e.g.,1536-wellor384-wellmicroplate)andperformingapilotscreenofasmalllibraryofcompounds.Further,theresearchersmightseekadvicefromthescreeninglaboratoryaboutorthogonal assays tovalidate the screeninghits, andabout chemical improvementof theinitialhitsviaastructure-activityrelationship(SAR)studyfollowinghitvalidation.3.HitvalidationHitsfromaprimaryscreenmaybesystematicallyassessedusingacascadeoffollow-upassaystoefficientlyandeffectivelyremovefalsepositives.PrimaryHTSassaystypicallygeneratehundredsto thousands of hits,many ofwhich are false positives or are chemically intractable.Hits fromsmallerscaleprimaryscreensarealsolikelytogeneratefalsepositivesorchemicallyintractablemoleculesthatrequireadditionalscreens.Awards:Applicationbudgetsarenotlimitedbutneedtoreflecttheactualneedsoftheproposedproject.LetterofIntent:30dayspriortotheapplicationduedate

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Deadline: Standarddatesapply,by5:00PMlocaltimeofapplicantorganization.Alltypesofnon-AIDSapplicationsallowedforthisfundingopportunityannouncementaredueonthesedates.Applicants are encouraged to apply early to allow adequate time to make any corrections toerrorsfoundintheapplicationduringthesubmissionprocessbytheduedate._____________________________________________________________________________________________GrantProgram:DiscoveryofCell-basedChemicalProbesforNovelBrainTargets(R21)Agency:NationalInstitutesofHealthPAR-17-335RFPWebsite:https://grants.nih.gov/grants/guide/pa-files/PAR-17-335.htmlBriefDescription:Technologicalinnovationsinchemicalsynthesis,cheminformatics,structuralbiology,andhighthroughputbioactivityanddrugpropertyassayshaveallowedrapiddiscoveryof novel, small-molecule probes for the study of disease-related biological processes andmechanismsinacademicenvironments.Through this funding opportunity NIMH, NIA, NICHD and/or NIDCD encourage applications toadvancethediscoveryofsmallmoleculechemicalprobesforuseincell-basedstudies.ThisFOAaimstostimulateresearchin:1)discoveryanddevelopmentofnovelcell-basedchemicalprobesfor their potential use in understanding biological processes relevant to the missions ofparticipating NIH Institutes; and 2) use of chemical probes to discover and/or validate novelbiologicaltargetsthatwill informstudiesofbraindiseasemechanisms.Emphasiswillbeplacedon the research thatprovidesnew insight into importantdisease-relatedbiological targets andbiological processes. For example, applications may involve emerging therapeutic targets andmechanisms for the discovery of chemical probes that may lead to further development oftherapeuticsorprovideinsightintothebiologyofrelevantdiseases.This program creates an opportunity for integrated research in biology and chemistry onstructure-activity relationships (SAR) of novel compounds through an iterative and paralleloptimization process, to advance successful development of cell-based chemical probes.ApplicantstothisFOAshouldhaveinhandthestartingcompounds(“validatedhits”)forchemicaloptimization and bioassays for testing new analog compounds. The iterative bioassay andchemicaloptimizationcyclesmayencompass:

• Cellularactivity(potencyincellularassays);• Cellular penetration (cellular permeability measured in relevant assays: Caco-2/MDR1-

MDCK/PAMPA);• Aqueoussolubility;• Selectivity(assessmentofon-targetandoff-targeteffectsincells);• Cellulartargetengagement(mechanismofaction)

Theabove-mentionedareasofinvestigationarerepresentativeandnotmeanttobeall-inclusive.ProjectsproposingthedevelopmentofphenotypicchemicalprobesarenotsuitableforthisFOA.ThemainemphasisofprojectssubmittedunderthisFOAshouldbeinthediscoveryofcell-basedchemical probes rather than chemical leads for drug or therapeutic discovery. Applicantsinterested in developingin vivochemical probes may wish to apply using the companion R01mechanism (PAR-17-336. Projects seeking resources for later stage drug development are notsuitableforthisFOA.Awards:Directcostsarelimitedto$275,000overatwo-yearperiod,withnomorethan$200,000indirectcostsallowedinanysingleyear.LetterofIntent:NotrequiredDeadline: Standarddatesapply,by5:00PMlocaltimeofapplicantorganization.Alltypesofnon-AIDSapplicationsallowedforthisfundingopportunityannouncementaredueonthesedates.

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Applicants are encouraged to apply early to allow adequate time to make any corrections toerrorsfoundintheapplicationduringthesubmissionprocessbytheduedate._____________________________________________________________________________________________GrantProgram:BRAINInitiative:NewConceptsandEarly-StageResearchforLarge-ScaleRecordingandModulationintheNervousSystem(R21)Agency:NationalInstitutesofHealthRFA-EY-17-002RFPWebsite:https://grants.nih.gov/grants/guide/rfa-files/RFA-EY-17-002.htmlBriefDescription:ThisFOAisrelatedtotherecommendationsinsectionsII.2,II.3,andII.4fromtheBRAIN2025Report.Thesethreerecommendationscall foraccelerateddevelopmentofnewlarge-scale recording technologies and tools for neural circuit manipulation. These newtechnologies and approaches will provide unprecedented opportunities for exploring how thenervoussystemencodes,processes,utilizes,stores,andretrievesvastquantitiesofinformation.Abetterunderstandingofthisdynamicneuralactivitywillenableresearcherstoseeknewwaystodiagnose,treat,andpreventbraindisorders.

Achieving these goals requires the ability to record simultaneously from thousands ortens-of-thousandsofneuronscontributingtothedynamicactivityinaneuralcircuit.Therelevantactivitymaybeinclustersofcellspackedcloselytogetherormaybeinwidelydistributedcircuits.Currentmicroelectrodeand imagingtechnologiesare limited inthenumberofcells fromwhichactivity can be isolated and sampled simultaneously, by the size or location of the area to besampled,bythedepthofpenetration,andbytheinvasivenessofthetechniquethatmightprohibittheir use in human experimentation. Non-invasive technologies suitable for use in humans arecurrentlylimitedinspatialresolutionandtemporaldynamics,aswellasintheirreflectionofon-goingelectricalactivity incircuitelements.ThisFOAseeksentirelynew ideas, conceptsand/orapproaches from physics and engineering, and biology, for how these limitations might beovercome to enable increased recording capabilities on the scale of one or more orders ofmagnitudebeyondthatofcurrenttechnology.ThisFOAalso seeksnovel ideas for technology capableofmanipulating activity in circuits thatovercomethelimitationsofcurrentinvasiveandnon-invasiveapproaches.Dissectingthefunctionof neural circuits requires the ability to manipulate neural activity in order to investigateunderlying mechanisms and demonstrate causality. Current technologies such asmicrostimulationandoptogeneticapproachesare limited inspecificity, temporaldynamics,andbytheinvasivenessofthetechnique.

Applications are expected topropose thedevelopmentof ideas in the earliest stages forentirelynewapproachesforlarge-scaleneuralrecordingand/ormanipulationofneuralactivity.Such ideas could encompass unique and innovative combinations of existing technology thatcreate a synergistic result. An important goal is to stimulate new thinking and concepts foracceleratingdevelopmentofnovel technologies thatbreak currentbarriers toneural recordingand/ormanipulation.Inadditiontoexperimentalapproaches,thisFOAmaysupportearly-stagetestingusingcalculations,simulations,computationalmodels,orothermathematical techniquesfor demonstrating that the signal sources and/or measurement technologies are theoreticallycapable of meeting the demands of large-scale recording ormanipulation of circuit activity inhumans or animalmodels. The supportmight also be used for building and testing phantoms,prototypes, in-vitro or other bench-top models in order to validate underlying theoreticalassumptionsinpreparationforfutureFOAsaimedatproof-ofconcepttestinginanimalmodels.

Applications are expected to propose research that will explore ideas in their earlieststages of development in order to be responsive to goals and objectives of this FOA. Someexamplesofnon-responsiveapplicationsmightbe:i)furtherdevelopmentofexistingtechnology;

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ii)hypothesis-testing;iii)validationand/orrefinementofcurrenttechnology;oriv)developmentof analyticalmethods to be applied to existing technology and/or data. Applications proposingwork that does notmeet the goals of this FOAwill be deemednon-responsive andwill not bereviewed.Awards:Thecombineddirectcostbudgetforthetwo-yearprojectperiodmaynotexceed$300,000.Nomorethan$200,000mayberequestedinanysingleyear.LetterofIntent:NotrequiredDeadline: October26, 2017, by5:00PM local timeof applicant organization.Alltypes of non-AIDSapplicationsallowedforthisfundingopportunityannouncementaredueonthisdate.Applicants are encouraged to apply early to allow adequate time to make any corrections toerrorsfoundintheapplicationduringthesubmissionprocessbytheduedate._____________________________________________________________________________________________GrantProgram:CentralNeuralMechanismsofAge-RelatedHearingLoss(R01)Agency:NationalInstitutesofHealthRFA-AG-18-017RFPWebsite:https://grants.nih.gov/grants/guide/rfa-files/RFA-AG-18-017.htmlBrief Description: This FOA encourages applications investigating the central neuralmechanismsofage-relatedhearingloss.Studiesthatexploretheneuralchangesthatoccurwith‘natural’aging fromthe innerear,along theauditorypathway to theauditorycortexarehighlyencouraged. Investigators may employ a variety of approaches including cellular, molecular,imaging,physiologicalandgenetic toaddress thisareaof research.Applications focusedon thedesignofhearingaidsandhearingassistivetechnologieswillbedeemednon-responsivetothisFOA andwill not proceed to review. Applications proposing clinical trialswill not be acceptedunderthisFOA.Studiesofinterestmayincludebutarenotlimitedtothefollowing:

• Examining the age-related cellular and molecular changes along the central auditorypathwayandtheirimpactonneuralactivity

• Examiningtheeffectsofmanipulatingthebalanceofexcitatory/inhibitoryneuralactivitytostudyneuralcircuitsalongtheauditorypathway

• Usingimagingtechniquestorevealpatternsofneuralreorganizationwithhearinglossandaging

• Investigating the central effects of age-related hearing loss on neural and perceptualprocessing

• Examininggeneexpressionchangesintheagingauditorysystem• Investigating thedegreeofneural activationobtained fromadiminishedauditory signal

andsubsequentchangeincorticalreorganization• Investigatinghownaturalaginginfluencescentralauditoryplasticity

Awards:Applicationbudgetsarelimitedto$500,000indirectcostsperyear.LetterofIntent:October8,2017Deadline: November8,2017,by5:00PMlocal timeofapplicantorganization.Alltypesofnon-AIDSapplicationsallowedforthisfundingopportunityannouncementaredueonthisdate.NolateapplicationswillbeacceptedforthisFundingOpportunityAnnouncement.Applicants are encouraged to apply early to allow adequate time to make any corrections toerrorsfoundintheapplicationduringthesubmissionprocessbytheduedate._____________________________________________________________________________________________GrantProgram:SmallGrantsonPrimaryImmunodeficiencyDiseases(R03)Agency:NationalInstitutesofHealthPAR-17-332

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RFPWebsite:https://grants.nih.gov/grants/guide/pa-files/PAR-17-332.htmlBriefDescription: ThisFOAandthecompanionFOAR21(PAR-17-333)arereissuesoffundingopportunities started in 2007 and renewed in 2010, 2013 and 2016. Numerous R21 and R03projects were awarded through this program covering a large spectrum of research topics inprimary immunodeficiency diseases such as: genetic dissection of these diseases;in vivoandinvitromodeldevelopment;thymicimplantationstrategies;therapeuticanddiagnosticapproaches;RNA interference approaches; induced pluripotent stem cell strategies; studies on immunedysregulation, DNA repair defects, glycosylation defects, and B cell tolerance defects;establishmentofregistriesandrepositories,andothers.ResearchObjectivesandScopeThis FOAwill support awide variety of small grants inprimary immunodeficiency research asoutlinedintheexamplesbelow.ResearchareassupportedbythisFOAinclude,butarenotlimitedto:

• Identifyingtheclinical,immunological,geneticandmolecularcharacteristicsofgeneticallydeterminedimmunodeficiencydiseases;

• Identifyingthemolecularbasisofprimaryimmunodeficiencydiseases;• Advancingourunderstandingofhowageneticvariantresultsinimmunodeficiency;• Discovering/developing improved diagnostic/newborn screening tools for primary

immunodeficiencydiseases;• Performingexvivostudieswithhumanspecimens:• Discovering/developingnewanimalmodelsforprimaryimmunodeficiencydiseases;and• Analyzing clinical data and samplesmaintained in primary immunodeficiency registries,

consortium databases and repositories to address questions relevant to primaryimmunodeficiencyresearch.

OtherresearchareassupportedbythisFOAincludestudiesofnoveltherapeuticapproachesfortreatmentofprimaryimmunodeficiencydiseasesto:

• Improve and better understand existing treatments of primary immunodeficiencydiseases;

• Understandcomplicationsassociatedwithprimaryimmunodeficiencydiseases;• Define environmental or other triggers that result in complications in individuals with

primaryimmunodeficiencydiseases;and• Identifyandvalidatebiomarkersforprimaryimmunodeficiencydiseases.

ResearchareasNOTappropriateforthisFOAincludestudiesof:• Immunodeficiencyresultingfrominfection(e.g.,HIV);• Immunodeficiency resulting from treatments (e.g., chemotherapy), exposures (e.g.,

radiation),ortherapies(e.g.,transplantation,orsurgery);• Immunodeficiencyresultingfromagingorimmaturity;and• Basic immunologic mechanisms unless related to understanding of primary

immunodeficiencydiseasesAwards:Abudgetfordirectcostsofupto$50,000peryearmayberequested(i.e.,amaximumof$100,000overtwoyears).LetterofIntent:NotrequiredDeadline: Standard datesapply), by 5:00 PM local time of applicant organization. Alltypes ofnon-AIDS applicationsallowed for this funding opportunity announcement are due on thesedates.Applicants are encouraged to apply early to allow adequate time to make any corrections toerrorsfoundintheapplicationduringthesubmissionprocessbytheduedate.

_____________________________________________________________________________________________

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DepartmentofDefense/USArmy/DARPA/ONRGrantProgram:DoD,PeerReviewedAlzheimer'sResearchAgency:DepartmentofDefenseW81XWH-17-PRARP-RPA DoDPeerReviewedAlzheimer's,ResearchPartnershipAwardW81XH-17-PRARP-CSRA DoD,PeerReviewedAlzheimer'sW81XWH-17-PRARP-QUAL DoD Peer Reviewed Alzheimer's, Quality of Life Research

AwardW81XWH-17-PRARP-NIRA DoD Peer Reviewed Alzheimer's, New Investigator Research

AwardWebsite:http://cdmrp.army.mil/prarp/defaultBriefDescription:SeveralResearchTopicsinBasicResearch:TheFY17DefenseAppropriationsActprovides$15million(M)totheDepartmentofDefensePeerReviewedAlzheimer'sResearchProgram(PRARP)tosupportresearchwhichaddressesthelong-termconsequencesoftraumaticbraininjury(TBI)astheypertaintoAlzheimer'sdisease(AD)andrelateddementias(ADRD).Theresearchimpactwillbenefitthemilitary,Veteran,andciviliancommunities.ThePRARP’smissionis devoted to (1) understanding the association between traumatic brain injury (TBI) andAlzheimer’s disease (AD)/Alzheimer’s disease-related dementias (ADRD) and (2) reducing theburdenonaffectedindividualsandcaregivers,especiallyinthemilitaryandVeterancommunities.ConsistentwiththePRARP'smissionandvision,theprogramfaces6overarchingchallengesforFY17.Theseoverarchingchallengesrepresentlongstandingresearchgoalsfortheprogram:

• Paucity of Research Resources:The paucity of research resources to examine theinterrelationship between TBI and subsequent AD/ADRD for the military, Veteran, andciviliancommunities.

• Paucity of Clinical Studies:The paucity of clinical studies to examine theinterrelationship between TBI and subsequent AD/ADRD for the military, Veteran, andcivilian communities. This includes research into risk factors which may predisposeindividualstoAD/ADRDsubsequenttoTBI.

• Diagnostic Technologies, Tests, Biomarkers, or Devices:The need for technologies,tests, or devices to detect or prognose the progression to AD/ADRD subsequent to TBI.This includes research into risk factors whichmay predispose individuals to AD/ADRDsubsequenttoTBI.

• Quality of Life:The need for technologies, assessments, interventions, or devices tobenefitindividualslivingwiththecommonsymptomsordeficitsofTBIandAD/ADRD.

• CaregiverBurden:Theneedfortechnologies,assessments,interventions,ordeviceswiththe goal of reducing burden for caregivers of individuals living with the commonsymptomsordeficitsofTBIandAD/ADRD.

• Epidemiology:Thepaucity of epidemiological research to examine the interrelationshipbetweenTBIandsubsequentAD/ADRDforthemilitary,Veteran,andciviliancommunities.This includes research into risk factors whichmay predispose individuals to AD/ADRDsubsequenttoTBI.

Awards:StandardGrantsProposalDeadline:September20,2017;Mayneedearliersubmissionofwhitepaper.ContactInformation:CDMRPHelpDesk:301-682-5507Email:help@eBRAP.org_______________________________________________________________________________________

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GrantProgram:FY2018BasicResearchChallenge(BRC)ProgramAgency:DepartmentofDefenseONRN00014-17-S-BA13Website: https://www.onr.navy.mil/en/Contracts-Grants/Funding-Opportunities/Broad-Agency-AnnouncementsBriefDescription:SeveralResearchTopicsinBasicResearch:Potentialfundamentalsciencequestions resolved by this BRC would be (1) is quantum wavefunction collapse an objectivefeature of quantum systems?, (2) are quantum models beyond the Schrodinger equationnecessary?,(3)arequantumtranslationalandrotationalfrictionexperimentallyobservable?,(4)arethereshort-rangecorrectionstothegravitationalconstantG?,and(5)howdoestheCasimirforce scale from the nano- to microscale, and how/why does it change from attractive torepulsive?The technologydeveloped to address thesequestionswill have the addedbenefit ofrealizing a variety of novel sensors. Research Concentration Area: (1) quantum foundations –experimentally explore quantum/classical boundary, test for quantum translational androtational friction; (2) quantum information - approaches for leveraging spins and levitatedparticlesforinformationprocessing;(3)precisionmeasurement-interrogategravitycorrectionsandCasimir forces at short length scales; (4) thermodynamics/statisticalmechanics - exquisitecontrol to constrain dynamics and then follow microscopic trajectories to build up ensembleaverages;and(5)materialspectroscopy-levitatingobjectsremovessubstrateinducedeffectsinperforming spectroscopy and microscopy on materials, which is especially crucial fornanomaterials.Alsoincludes:This BRC program requires a multidisciplinary integrated computational, experimental, andmulti-scale characterization effort including, but not limited to, (1) high-throughput CALPHADcomputations of phase equilibria/non-equilibrium solidification; (2) high-throughputexperiments using materials libraries with microstructural gradients; (3) deformation,strengthening modeling and validation; (4) multi-scale microstructural characterization; (5)phase stability/phase transformation kinetics; (6) lattice distortions and dislocations; (7)materialssynthesis/characterization;and(8)multi-scalemechanics.Possibleperformerswouldmost likely be a small research group with interdisciplinary expertise in quantum chemistry,materials science,materials informatics, interfacial and surface science,mechanics, 2D, 3D, and4Datomisticcomputationalsimulationsandmodeling,statisticalmechanics,moleculardynamics,phase-fieldmodeling,non-equilibriumprocessing,CALPHADandmulti-scalethermodynamicandkineticcomputational tools.Thesemulti-scalemodellingeffortswouldbevalidatedandverifiedusingstate-of-the-artatomic-scaleanalyticaltools.Awards:StandardGrantsProposalDeadline:WhitePapers:Friday,18August2017;FullProposals:Friday,17November2017ContactInformation:Dr.ReginaldWilliamsBasicResearchChallenge(BRC)ProgramManagerCode03ROfficeofNavalResearch875NorthRandolphStreetArlingtonVA22203-1995reginald.g.williams@navy.mil_______________________________________________________________________________________GrantProgram:CENTEROFEXCELLENCE:TrustedHuman-MachineTeamingAgency:DepartmentofDefenseAFOSRWebsite:http://www.wpafb.af.mil/Welcome/Fact-Sheets/Display/Article/842050/Brief Description: The Air Force Office of Scientific Research (AFOSR) seeks unclassifiedproposalsfromeducationalinstitutionsintheUnitedStatesforaUniversityCenterofExcellence

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(UCoE) in in Trusted Human-Machine Teaming. Proposals must not contain any proprietaryinformation.ThiscenterisajointprojectbetweentheAirForceOfficeofScientificResearchandthe Air Force Research Laboratory, Airman Systems Directorate (AFRL/RH), referred tocollectively as “we, our, or us” in this announcement. The center will extend the researchcapabilitiesoftheAirForceResearchLaboratory,andprovideopportunitiesforanewgenerationofUnitedStatesscientistsandengineerstoaddressthebasicresearchneedsoftheAirForce.Wewillconsiderproposalsforuptofive(5)yearswithathree-year(3)baseperiodandatwo-year(2)optionperiod.ofInterestacrossthelifespanofanindividualwithASD,areofparticularimportancetotheARP.Awards:Upto$5,000,000ProposalDeadline:August18,2017ContactInformation:DR.BENJAMINKNOTT,AFOSR/RTA2TrustandInfluenceProgramTelephone:(703)696-1142Email:benjamin.knott.2@us.af.milDR.ERICAJOHNSON,AFRL/711HPW/RHCPAppliedNeuroscienceBranchTelephone:(937)938-3569Email:erica.johnson.7@us.af.mil

___________________________________________________________________________________DepartmentofEnergyGrantProgram:AdvancedManufacturingGraduate-LevelTraineeshipsAgency:DepartmentofEnergy DE-FOA-0001790Website:https://eere-exchange.energy.gov/#FoaId365cf14b-d1bc-40f9-9a35-08a8d336d4e7BriefDescription:ThroughthisFundingOpportunityAnnouncement(FOA),DOEintendstofunduniversity-led Traineeship Programs that address workforce training needs in the early-stagetechnology area of advanced materials and process technologies of high importance tomanufacturing. The following objectives guide the Office of Energy Efficiency and RenewableEnergy(EERE)AdvancedManufacturingOffice’s(AMO)traineeshipefforts:

• Advance the DOE mission – Traineeship programs are designed and implemented toadvance specific Science, Technology, Engineering and Math (STEM) workforcecompetencies required for the DOE’s unique mission to ensure America’s security andprosperity by addressing its science and energy challenges, particularly with regard toadvancedmanufacturing.

• Address priority STEM workforce needs and identified gaps in early-stage advancedmanufacturingtechnology–TraineeshipprogramsfocusonadvancingthosecriticalSTEMdisciplines and competencies specifically relevant to theAMOmissionswhereotherU.S.GovernmentoracademicworkforcedevelopmentprogramseitherdonotexistorwhereDOE-relevantearly-stagetechnologyareasarenotbeingleveragedtosupportspecificDOEmissionresponsibilities.

The high priority topic identified in this traineeship program is advanced manufacturing(advancedmaterialsandprocesstechnologiesinmanufacturing).Award: EERE expects tomake approximately $2,500,000 of Federal funding available for newawardsunderthisFOA,subjecttotheavailabilityofappropriatedfunds.EEREanticipatesmaking

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approximately1-2awardsunderthisFOA.EEREmayissueone,multiple,ornoawards.Individualawardsmayvarybetween$1,250,000and$2,500,000.ProposalDeadline:

• ConceptPaperSubmissionDeadline:8/8/20175:00PMET• FullApplicationSubmissionDeadline:9/13/20175:00PMET

ContactInformation:EERE-ExchangeSupport@hq.doe.gov_________________________________________________________________________________________________Grant Program: Technology Development to Ensure Environmentally Sustainable CO2InjectionOperationsAgency:DepartmentofEnergy DE-FOA-0001725Website:https://www.fedconnect.net/FedConnect/PublicPages/PublicSearch/Public_Opportunities.aspxBrief Description: This FOA seeks applications on research to develop techniques, tools, andmethodologies that improve detection and assessment of CO2 stored in the target reservoir.Research products developed under this FOA are expected to include monitoring tools andtechniques, as well as validation of models and modeling techniques. Successful technologiesdevelopedunderthisFOAwilldecreasetheoperator’sfinancialburdenassociatedwithlong-termmonitoringbyprovidingthemthecapabilitytoassessthepositionoftheCO2plumeinthetargetreservoir with greater certainty throughout the life cycle of the project (i.e., active- and post-injection).Award:Upto$2,000,000ProposalDeadline:August11,2017ContactInformation:K.Young412-386-4402bethan.young@netl.doe.gov

_________________________________________________________________________________________________NASAGrantProgram:ROSES2017:SolarIrradianceScienceTeamAgency:NASANNH17ZDA001N-SISTWebsite:https://nspires.nasaprs.com/external/solicitations/summary.do?solId=%7B74B6448A-AF9D-A1F6-9ED7-ABD7FF9C90C8%7D&path=open&method=initBriefDescription:SolarirradiancerepresentstheprimaryexternalforcingthatoperatesontheEarth and contributes to variability and change in the Earth’s climate and atmosphericcomposition.Itcanonlybemeasuredabovetheatmospheregiventhesignificantabsorptionthattakesplacewithinit.TheEarthsystemissensitivetovariationsinboththeTotalSolarIrradiance(TSI), as well as the spectral dependence of any variation, given the fact that differentwavelengthshavetheirgreatestabsorptionatdifferentaltitudesintheatmosphere.VariationsinTSIarequitesmall–thetypicalvariationoverthe11-yearsolarcycleisontheorderof±0.15%.Variations in the solar irradiance as a function of wavelength increase with decreasingwavelength, potentially being of the order of a fewpercent at the shortwavelength ultravioletradiationresponsibleforphotodissociationofoxygenandafactoroforderunityatwavelengthsnearLymanAlpha(121.6nm).Awards:VariousProposalDeadline:

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SIST17NOIsDue Aug04,2017SIST17ProposalsDue Oct06,2017Contact: David B. Considine Earth Science Division Science Mission Directorate NASAHeadquarters Washington, DC 20546-0001 Tel: 202-358-2277 Email:david.b.considine@nasa.gov_________________________________________________________________________________________________GrantProgram:ROSES2017:New(EarlyCareer)InvestigatorProgramAgency:NASANNH17ZDA001N-NIPWebsite:https://nspires.nasaprs.com/external/solicitations/summary.do?method=init&solId={344D6EF1-D56F-60FD-505E-A31035E2B19C}&path=openBrief Description: The New (Early Career) Investigator Program (NIP) in Earth Science isdesigned to support outstanding scientific research and career development of scientists andengineers at the early stage of their professional careers. The program aims to encourageinnovative research initiatives and cultivate scientific leadership in Earth system science. TheEarthScienceDivision(ESD)placesparticularemphasisonthe investigators'abilitytopromoteand increase the use of space-based remote sensing through the proposed research. The NIPsupportsallaspectsofscientificandtechnologicalresearchaimedtoadvanceNASA’smissioninEarth system science (http://science.nasa.gov/about-us/sciencestrategy/). In research andanalysis,thefocusareasare:•CarbonCycleandEcosystems,•ClimateVariabilityandChange,•WaterandEnergyCycle,•AtmosphericComposition,•Weather,and•EarthSurfaceandInterior.In Applied Sciences, the ESD encourages efforts to discover and demonstrate practical uses ofNASA Earth science data, knowledge, and technology (see http://appliedsciences.nasa.gov). Intechnologicalresearch,theESDaimstofosterthecreationandinfusionofnewtechnologiesintospacemissionsinordertoenablenewscientificobservationsoftheEarthsystemorreducethecost of current observations (see http://esto.nasa.gov). The ESD also promotes innovativedevelopment incomputingand informationscienceandengineeringofdirect relevance toESD.SeeAppendixA.1formoredetaileddescriptionsoftheFocusAreas, themesinappliedsciences,andrelatedresearchtopicsofhighprioritytotheESD. The proposed research projectmust be led by a single, eligible (see further descriptionbelowforeligibility)investigatorservingasthePrincipalInvestigator(PI).Indeed,thisindividualmust be the only essential team member; no Co-Investigators (Co-Is), paid or unpaid, arepermitted.TheNIPdoesnotacceptproposalswithCo-PIsnortwotypesofPIs,suchasSciencePIand Institutional PI. Students and postdoctoral fellowsmay participate as paid teammembers.The proposed research may include collaborations. See the Guidebook for Proposers athttp://www.hq.nasa.gov/office/procurement/nraguidebook/ for the definitions of Collaboratorvs.Co-InvestigatoranddescriptionsofChina-relatedrestrictions.TobeeligibleforanNIPaward,proposedPIsmustmeetthefollowingrequirements:1.BeemployedataninstitutionintheU.S.,itsterritories,orpossessions,ortheCommonwealthofPuertoRico,whichawardsabaccalaureateoradvanceddegreeinafieldsupportingtheobjectivesof NASA Earth system studies, or be employed at any nonprofit research institution or othernonprofitorganizationthatperformsasignificantamountofworkinfieldsofresearchsupportingthe objectives of NASA’s Earth Science Program. Such organizations could include museums,observatories,Governmentornonprofitresearchlaboratories,aswellasnonprofitentitiesintheprivatesector.

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2.Beintenure-ornontenure-trackpositionsineitherteachingorresearchorboth,aslongastheemployinginstitutionassumestheresponsibilityofsubmittingtheproposalwiththeindividualastheproposedPI.3.DespitebeingmorethanfiveyearsbeyondthereceiptoftheirPh.D.degrees, individualswhohave interrupted theircareers forreasonssuchas family leaveorserioushealthproblemsmayalsobeeligible.TheseapplicantsshouldmakeawrittenrequestforpriorconcurrencefromNASAbeforetheduedateforNoticesofIntenttopropose.NASAwillprovideawrittenresponsewithinthreeweeks.Suchexceptionisnotintendedforindividualswhohavehadsuccessfulemploymentin technical fields in science and engineering, even though the employment is not a directcontinuationoftheirPh.D.research,norisitintendedforindividualswitharecentPh.D.degreeafter having already established a successful career in Earth system science and relateddisciplines.4. Not hold or have held tenure (or equivalent) on or before the submission deadline of thisprogram.5.NotbeacurrentorformerrecipientoftheNIPorPresidentialEarlyCareerAwardforScientistsandEngineers(PECASE)(seefurtherbelow)award.Awards:ProposalstotheNIPareopenlysolicitedapproximatelyeverytwoyears.Theanticipatedaverage award is $80-90K per year for a period of up to three years, subject to satisfactoryprogressandavailabilityoffunds.ProposalDeadline:NIP17NOIsDue:July31,2017NIP17ProposalsDue:August31,2017Contact:LinChambersEarthScienceDivisionScienceMissionDirectorateNASAHeadquartersWashington,DC20546-0001Telephone:202-358-1667E-mail:lin.h.chambers@nasa.gov

_________________________________________________________________________________________________NationalEndowmentofHumanitiesGrantProgram:SummerAwardsAgency:NationalEndowmentofHumanitiesWebsite:https://www.neh.gov/grants/research/summer-stipendsBriefDescription:SummerStipendssupport individualspursuingadvancedresearchthat isofvaluetohumanitiesscholars,generalaudiences,orboth.Eligibleprojectsusuallyresultinarticles,monographs,books,digitalmaterialsandpublications,archaeologicalsitereports,translations,oreditions. Projects must not result solely in the collection of data; instead they must alsoincorporateanalysisandinterpretation.

SummerStipendssupportcontinuousfull-timeworkonahumanitiesprojectforaperiodoftwoconsecutivemonths.SummerStipendssupportprojectsatanystageofdevelopment.Awards:$6,000stipend.ProposalDeadline:September27,2017forProjectsBeginningMay2018Contact:ContactNEH’sDivisionofResearchProgramsat202-606-8200orstipends@neh.gov.

_________________________________________________________________________________________________

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BurroughsWelcomeFund

GrantProgram:BWF’sCareerAwardsattheScientificInterfaceAgency:BurroughsWelcomeFundWebsite: https://www.bwfund.org/grant-programs/interfaces-science/career-awards-scientific-interfaceBrief Description: These grants are intended to foster the early career development ofresearchers who have transitioned or are transitioning from undergraduate and/or graduatework in the physical/mathematical/computational sciences or engineering into postdoctoralworkinthebiologicalsciences,andwhoarededicatedtopursuingacareerinacademicresearch.Scientific advances such as genomics, quantitative structural biology, imaging techniques, andmodeling of complex systems have created opportunities for exciting research careers at theinterfacebetweenthephysical/computationalsciencesandthebiologicalsciences.Tacklingkeyproblems in biologywill require scientists trained in areas such as chemistry, physics, appliedmathematics,computerscience,andengineering.ApplicationProcess:The competition will employ a two-stage process. Pre-proposals will be reviewed and fullproposalinvitationswillbesentbyNovember14,2017.Allapplicantswillberequiredtocompleteaweb-basedquestionnaireassessingtheireligibilitytoapplyforthisaward.Ifeligibilitycriteriaaremet,applicantswillbeautomaticallydirectedtotheweb-basedpre-proposalapplication.Awards:BWF'sCareerAwardsattheScientificInterface(CASI)provide$500,000overfiveyearstobridgeadvancedpostdoctoraltrainingandthefirstthreeyearsoffacultyservice.Theseawardsare open to U.S. and Canadian citizens or permanent residents as well as to U.S. temporaryresidentsProposalDeadline:Sept.6,2017:Pre-proposaldeadlineNov.14,2017:InvitationssentJan.10,2018:FullproposaldeadlineMar.23,2018:FinalistsnotifiedApr.25-26,2018:In-personinterviewsContact:RustyKelley,Ph.D.,ProgramOfficer,919-991-5120Formoreinformation,pleasealsocontactEricBlitz,AssociateDirectorforDevelopmentCorporateandFoundationRelations,eric.blitz@njit.edu

_________________________________________________________________________________________________

BayerGrants4Targets

GrantProgram:AlfredP.SloanFoundationGrantsAgency:BayerFoundationWebsite:https://grants4targets.bayer.com/home/pharma/BriefDescription:Bayerisofferinggrantsforresearchersinvestigatingnoveldrugtargetsin:·Oncology(Focusononcogenicsignaling)·Gynecology(Focus on novel treatment options for endometriosis, uterine fibroids and polycystic ovarysyndrome(PCOS).·Heart&VascularDiseases

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(Focus onAtrial Fibrillation, ChronicHeart Failure, PeripheralArteryDisease, Cardioprotectivemechanisms.)·SpecialtyLungDiseases(FocusonIdiopathicPulmonaryFibrosis,InterstitialLungDisease,COPD-FrequentExacerbators,ChronicCough,PulmonaryHypertension).·KidneyDiseases(Focus on Hypertensive Nephropathy, Diabetic Kidney Disease, Acute Kidney Injury, ChronicAllograftNephropathy,PolycysticKidneyDisease)·Hemostatic&AcuteOrganDisorders(Focus on Acute Respiratory Distress Syndrome, DIC, SIRS, Acute Coronary Syndrome, StrokePreventioninAtrialFibrillation,VenousThrombosis,HemophiliaA).

• Targetmustbeanucleicacidoraprotein(e.g.anenzyme,areceptor)whoseactivitycanbemodifiedbyadrug(drugcanbeasmall-molecular-weightchemicalcompoundorabiological,suchasanantibodyorarecombinantprotein)

• Targetshouldhaveshowntobeeffective/mechanistically involved in thediseasebyrelevantinvitroorinvivomodels

• Targetisdisease-modifyingand/orhasaprovenfunctioninthepathophysiologyofadisease

Awards:Therearetwotypesofgrants,Supportgrants(€5,000-€10,000)*Fordruggabletargetsthatareataveryearlystageofdiscovery.Focusgrants(€10,000-€125,000)*Formorematureideas,e.g.toaddressspecificaspectsofatargetasafirststeptowardstransferringittothedrugdiscoveryprocess.ProposalDeadline:August31,2017Contact:Formoreinformation,pleasealsocontactEricBlitz,AssociateDirectorforDevelopmentCorporateandFoundationRelations,eric.blitz@njit.edu

_________________________________________________________________________________________________

SimonFoundationGrantProgram:SimonsGrantsforSabbaticalsinMathandTheoreticalPhysicsAgency:SimonFoundationWebsite: https://www.simonsfoundation.org/funding/funding-opportunities/mathematics-physical-sciences/simons-fellow-program/BriefDescription:Grantsawardedwillberestrictedtosabbatical-eligiblefacultywhowishtousethegrantforthepurposeofextendingasingletermsabbaticalleavetoafullacademicyear.ProposalDeadline:September28,2017Contact:Formoreinformation,pleasealsocontactEricBlitz,AssociateDirectorforDevelopmentCorporateandFoundationRelations,eric.blitz@njit.edu

_________________________________________________________________________________________________

2017/2018Institutional Review Board (IRB)Meeting Schedule for Approval of HumanSubjectsinResearchIRBapplicationformsmustbereceivedbytheIRBatleast7businessdaysbeforethemeetingtoensureenoughtimeforaccuratereview.Ifitisreceivedafterthat,itwillreviewedatthefollowingmonth'smeeting.

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• Thursday,August3,2017• Tuesday,September12,2017• Tuesday,October10,2017• Tuesday,November7,2017• Tuesday,December5,2017• Tuesday,February6,2018• Tuesday,March6,2018• Tuesday,April10,2018• Tuesday,May8,2018

More information about IRB forms and process is posted on the research websitehttp://www.njit.edu/research/compliance/review-board/

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2017-2018InstitutionalBiosafetyCommittee(IBC)MeetingScheduleIBC application forms must be submittedat least 10 business daysbefore the next meetingdate.SubmityourformstoIBC@njit.edu.

• Tuesday,September26,2017• Tuesday,November28,2017• Tuesday,February20,2018• Tuesday,April24,2018

More information about IBC forms and process is posted on the research websitehttp://www.njit.edu/research/compliance/biosafety-committee.php

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StreamlyneUpdate

513proposalsweresubmittedinFY17.SinceJanuary17,307proposalsweresubmittedthroughstreamline. Inthe lastquarter(April-July),34proposalsweresubmittedthroughtheSystem-to-System(S2S)Streamlyne-Grants.govmodule.New“HowtoDo”videoshavebeenpostedontheresearchwebsite http://www5.njit.edu/research/streamlyne/. These videos show step-by-stepprocessonthefollowingtasks: ♦HowtoBeginProposalSubmissioninStreamlyne

♦HowtoInputProposalBudget♦HowtoProcessApprovals♦HowtoUploadProposalAttachments

In addition,most Frequently AskedQuestion (FAQs) from PIs are postedwith answers on thesamewebsiteas StreamlyneFAQsFaculty and staff having any questions on proposal submission, may contact their collegerepresentatives, and also followupwith JustinSamolewicz, Associate Director (Pre Award)973-596-3145;justin.m.samolewicz@njit.edu; and Eric Hetherington, Director, SponsoredResearch Programs Administration 973-596-3631;eric.d.hetherington@njit.edu. The collegerepresentativestohelpPIsonproposalsubmissionsare

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JohnMcCarthy,NCEDirectorofResearch(973)596-3247;john.p.mccarthy@njit.eduCristoLeon,CSLADirectorofResearch(973)596-6426;cristo.e.yanezleon@njit.eduNancyHenderson,CCSProjectManager973-596-5687;nancy.henderson@njit.eduIrisPantoja,CoADandSOMProjectManager973-596-4483;irp3@njit.edu__________________________________________________________________________________________