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Normal Conduction

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Page 1: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

Normal Conduction

Page 2: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

Normal ECG

Page 3: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

Electrical Activation of the Heart

Page 4: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

Conduction Times Across the Heart

40 ms

80 ms

Page 5: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

Conduction with LBBB

Page 6: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

RBBB

S

R’

Rapid activation

Slow muscle to muscle activation producing a wider deflection

Activation in LBBB

r s

Page 7: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

LBBB Criteria

• QRS duration ≥120 ms

• Q wave absent in lateral leads (exception - aVL)

• R peak time prolonged by >60 ms in V5, V6

• R peak time normal in V1

Page 8: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

LBBB

Page 9: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

LBBB

Page 10: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

Why is the QRS Complex Wide in LBBB?

• Is it because of interventricular septum?

• Or, because of delay of impulse within the left ventricle?

Page 11: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

QRS axis in the Frontal Plane

• Usually no QRS shift

• Superior axis indicates pre-existing LAFB, advanced heart disease and higher mortality

• Right axis is less common (RVH or MI)

Page 12: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

LBBB and Normal Axis

Page 13: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

LBBB and L Axis

Page 14: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

LBBB With Leftward Axis

Page 15: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

LBBB with Right Axis Deviation

Page 16: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

LBBB and Diagnosis of MI

Page 17: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

©2016 MFMER | 3580791-17

Results of Univariate Analysis of Electrocardiographic Criteria

Sgarbossa et al: NEJM 334(8): 481, 1996

Criterion Sensitivity (95% CI)

Specificity (95% CI)

Positive Likelihood ratio

(95% CI)

Negative Likelihood ratio

(95% CI) ST-segment elevation ≥1 mm and concordant with QRS complex

73 (64–80) 92 (86–96) 9.54 (3.1–17.3) 0.30 (0.22–0.39)

ST-segment depression ≥1 mm in lead V1, V2, or V3

25 (18–34) 96 (91–99) 6.58 (2.6–16.1) 0.78 (0.7–0.87)

ST-segment elevation ≥5 mm and discordant with QRS complex

31 (23–39) 92 (85–96) 3.63 (2.0–6.8) 0.75 (0.67–0.86)

Positive T wave in lead V5 or V6

26 (19–34) 92 (86–96) 3.42 (0.18–65) 0.80 (0.72–0.9)

Left-axis deviation 72 (63–79) 48 (39–57) 1.38 (1.13–9.8) 0.59 (0.25–1.39)

Page 18: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

LBBB With Upright T

Page 19: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

LBBB with Upright T (L Axis)

Page 20: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

LVH and LBBB

• S in V2 + R in V6 >4.5 mV

• LAE

• QRS >160 ms

Page 21: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

Criteria for LAFB

• Frontal plane QRS axis -45º to 90º

• QRS ≤120 ms (or 110 ms)

• rS patterns in leads II, III and aVf

Page 22: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

Activation in LAFB

Page 23: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

LAFB and aVR

• QRS complex in aVL and aVR, each end in an R wave

• Peak of the terminal R occurs later in aVR than in aVL (against aVR earlier in inferior MI)

AJC 51:723, 1983

Page 24: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

LAFB - aVR Delay

Page 25: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

Inferior Infarct

Page 26: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

Inferior MI and LAFB

Page 27: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

LAFB and Pseudo infarct

• Commonest cause for pseudoinfarction secondary to poor R wave progression

• A less common is the erroneous diagnosis of septal infarction secondary to small q waves in the right precordial leads

• Record one space below

Page 28: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

LAFB and PRWP

Page 29: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

LAFB

Page 30: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

LAFB

Page 31: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

LAFB, Delay in aVR and PRWP

Page 32: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

LAFB and LVH

• R in aVL may cause false positive LVH

• Highly sensitive and specific criteria is the sum of S in LII and of the largest QRS complex in precordial leads is ≥3.0 mV

Page 33: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

Criteria for LPFB

• Frontal Plane QRS axis ≥120°

• RS in leads I and aVL with qR patterns in inferior leads

• QRS duration <120 ms

• Exclusion of other factors causing right axis deviation (eg, RV overload, lateral infarction)

Page 34: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

LPFB

Page 35: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

LPFB

Page 36: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

RBBB

r

S

R

Rapid activation

Slow muscle to muscle activation producing a wider deflection

Activation in RBBB

Page 37: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

RBBB

Page 38: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

RBBB and LAFB

Page 39: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

RBBB and LAFB

Page 40: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

RBBB and LAFB

Page 41: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

RBBB and LPFB

Page 42: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

RBBB, LAFB and RVH

When R’ is taller than 15mm

Page 43: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

Incomplete RBBB (<120 ms)

• Delayed activation of RVOT

• R1 voltage may correlate with severity of PS

• R1 voltage may disappear after corrective surgery

QRS 116 msec

Page 44: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

Intermittent LBBB

Page 45: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

Anterior MI/RBBB/LAFB

Page 46: No Slide Title€¦ · LBBB with Right Axis Deviation . LBBB and Diagnosis of MI ©2016 MFMER | 3580791-17 Results of Univariate Analysis of ... RBBB and LAFB . RBBB and LAFB . RBBB

LAFB