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4th Summer School in Surgical Robotics, Montpellier 2009
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M. Hagen
Center for the Future of SurgeryUniversity of California San Diego
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NOTES????
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NOTES!!!
Natural Orifice Translumenal Endoscopic Surgery:
- Intentional puncture of one of the viscera (e.g., stomach, rectum, vagina, urinary bladder) to access the abdominal cavity
- With an endoscope (flexible or stiff)
- To perform an intraabdominal operation
Pearl JP, Ponsky JL: J Gastrointest Surg. 2007 Dec 5
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NOTES before NOTES I
Dimitri Oskarovich Ott performed the first endoscopic examination of the abdominal cavitythrough a posterior vaginal incision using a headmirror and speculum:
1st VENTROSCOPY
Ott, Ventroscopia. Zhurnal Akusherstva I Zhenskikh Boleznel. 1901;15:1045–1049
1900 1950 1990 2000 2002 2004 2006 2008
1901
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1900 1950 1990 2000 2002 2004 2006 2008
1944
Decker A, Cherry T. Culdoscopy, a new method in diagnosis of pelvicdisease. Amer J Surg. 1944;64:40–44
Culdoscopy
NOTES before NOTES II
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1900 1950 1990 2000 2002 2004 2006 2008
2001
Tsin DA, J Am Assoc Gynecol Laparosc. 2001 Aug;8(3):438-41
Operative Culdolaparoscopy (MA-NOS)
NOTES before NOTES I
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Open surgery
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Operating Theater
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Surgical Instruments
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Development of Laparoscopy
Georg Kelling1st experimental laparoscopy in 1910 in dogs
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Robotic Surgery
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Single Incision Laparoscopy I
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Single Incision Laparoscopy II
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Single Incision Laparoscopy III
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Single Incision Robotic Laparoscopy I
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Single Incision Robotic Laparoscopy II
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Single Incision Robotic Laparoscopy III
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NOTES
Dimension ofNOTES
T
More complex anddetailed lab research
ClinicalNOTES In 1st world
2007/2008
Kalloo`s firstPublication 2004
Basic experiments
First patients: Rao`s AE2004
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Kalloo AN, Gastrointest Endosc. 2004 Jul;60(1):114-7
Acute and survivalmodels in pigs:
- Transgastric access- Peritoneal cavityexploration
- Liver biposy- Gastric closure
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NOTES
Dimension ofNOTES
T
More complex anddetailed lab research
ClinicalNOTES In 1st world
2007/2008
Kalloo`s firstPublication 2004
Basic experiments
First patients: Rao`s AE2004
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NOTES: First PatientsReddy & Rao
« Per oral transgastricendoscopic appendectomy in human. »
45th Annual Conference of the Society of GastrointestinalEndoscopy of India; February, 2004; Jaipur, India.
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NOTES
Dimension ofNOTES
T
More complex anddetailed lab research
ClinicalNOTES In 1st world
2007/2008
Kalloo`s firstPublication 2004
Basic experiments
First patients: Rao`s AE2004
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NOTES: Further Research• Tubal Ligation• Cholecystectomie• Gastrojejunostomie• Oophorectomie• Tubectomie• Splenectomie• Nephrectomie• Pankreatic Resection
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NOTES
Dimension ofNOTES
T
More complex anddetailed lab research
ClinicalNOTES In 1st world
2007/2008
Kalloo`s firstPublication 2004
Basic experiments
First patients: Rao`s AE2004
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UCSD
Research and clinical NOTES in USA
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Why NOTES???
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Rationale for NOTES
- No abdominal wall incisions
- No wound infections and hernias
- Less pain
- Less adhesions
Is NOTES less invasive than any other kind of surgery???
- NO scars perfect cosmetic outcomes
www.noscar.org
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Importance of cosmetics
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Geneva Cosmesis StudyOnsight poll at "day of open wards“ + ongoing interviews
Questionnaire:
- Importance of cosmetic issues in abdominal surgery
- Satisfaction with previous scars
- Favoritism of scarless surgery
- Favoritism of scarless surgery if risks are increased
- Accepted percentage of risk rise
- Importance of further research and investmentsQuestions answered on VAS from 0 to more than 100% or 1 to 10
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Conclusion Geneva cosmesis study- People strongly favor the idea of scarless abdominal surgery
- No differences between genders have been found
- Certain risks are accepted in order to achieve scarless surgery
- Further research and investments seems important
People have a desire for NOTES!!!
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Rationale for NOTES II
The NOTES-concept :
Human ingenuity and technological advance can continue to reduce the trauma and discomfort of effective surgery
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NOTES Today at UCSD
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Cholecystectomy
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Transvaginal Cholecystectomy I
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Gastric Sleeve Resection
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Transvaginal Gastric Sleeve Resection
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Umilical Hernia Repair
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Transvaginal Umbilical Hernia Repair
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Appendectomy
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Transgastric Appendectomy
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Transresctal Surgery I
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Transresctal Surgery II
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NOTES Limitations
• Safe Access• Installation and Maintanance of
Pneumoperitoneum• Unstable Vision & Operating Platform• Insufficient Tools• Limited Retraction• Closure
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NOTES: Access
Conventional laparoscopic trocars
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NOTES: Access without trocars
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NOTES: Access I
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NOTES: Access II
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NOTES: Access III
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NOTES: Access III
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NOTES: Operating Platforms I
USGI, USA
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NOTES: Operating Platforms II
USGI, USA Boston Scientific, USA
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NOTES: Operating Platforms III
D. Scott, USA
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NOTES: Tools I
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NOTES: Tools II
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NOTES: Retraction
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NOTES: Closure I
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NOTES: Closure II
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NOTES: Closure III
• T-tag applier + knotting element
• 2.8 mm channel
• Closure of porcine colon perforation demonstrates equivalency to surgery with advantages for adhesion formation
Ethicon Endosurgery, USA
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BUT:
All instrumentation not designedfor intraabdominal surgery
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Robots for NOTES
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Project "ARAKNES"Array of robots augmenting the Kinematics of Endo-luminal surgery
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The future is hard to predict…
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Does NOTES have a future?NOTES, by addressing “Sources of Invasion”, represents the next logical progression of
surgical development, a key step along the MIS continuum
Sources of Invasion• Abdominal wall incisions• Post-op recovery/RTNA• General anesthesia• Financial burden• Site of care• Infrastructure requirements• Clinician skill level
Open NOTESLaparoscopic/
Sustaining Improvements
“Hybrids”
Endoscopically-Assisted
Laparoscopy
Laparoscopically-Assisted Endoscopy
Intra-lumenal
Non-Invasive
AppendectomyCholecystectomy
Diagnostic Peritoneoscopy
Ventral Hernia
??
??
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“We must not say every mistake is a foolish one”
Cicero (106 BC – 43 BC)
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The effect of NOTES
0
0.5
1
1.5
2
2.5
3
Invasiveness
T
Laparoscopy
Flexible Endoscopy
- Less invasive- New approaches
- More invasive- New, effectiveinstruments forintralumenalmanipulation
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Protecting valuables!
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Thank you very much for your attention!