nutrition & disease causes & cures · pdf...
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NUTRITION & DISEASE CAUSES & CURES
COPE # 20028 GO
Dr. Steven M. Newman
Board Cer)fied Optometric Physician Board Cer)fied Nutri)on Specialist
Miami Ft. Lauderdale
Hippocrates
“He who does not know food, how can he
understand the diseases of man?”
Hippocrates
“If we could give every individual the right amount of nourishment and exercise, not too liKle and not too much, we would have found
the safest way to health.”
Plato
“We shall eat animals only at our own peril.”
“No other industry holds its customers in such disregard. What we have is a ‘sick care’ system that is reactive to problems. The
integrative approach puts the patient at the center by being preventative, predictive and
personalized.”
Ralph Snyderman, MD Chancellor Emeritus, Duke University School of Medicine
What generaNon are you from?
1900-‐1924 -‐ G.I. GeneraNon 1925-‐1945 -‐ Silent GeneraNon 1946-‐1964 -‐ Baby Boom
1965-‐1979 -‐ GeneraNon X 1980-‐2000 -‐ Millennials or GeneraNon Y
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Latest generaNon?
XXL
Being overweight and obese raise the risk for:
type 2 diabetes high blood pressure high cholesterol levels coronary heart disease congestive heart failure angina pectoris stroke asthma osteoarthritis musculoskeletal disorders gallbladder disease sleep apnea and respiratory problems gout bladder control problems
poor female reproductive health complications of pregnancy menstrual irregularities infertility irregular ovulation erectile dysfunction cancers of the uterus breast prostate kidney liver pancreas esophagus colon and rectum
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In 2006, cardiovascular disease cost the U.S. close to $400 billion in direct and indirect
costs. -‐-‐-‐
Gaziano, Thomas A. "Reducing The Growing Burden Of Cardiovascular Disease In The
Developing World". Health Affairs. Vol. 26, No. 1, pp. 13.
Heart disease, stroke treatment costs to breach $500B in 2010
Cardiovascular Business.com
December 22, 2009
This recent study demonstrated that the cost of treaNng cardiovascular disease could rise by
64% to 84% by 2025.
The Future of Cardiology: UNlizaNon and costs of care". Journal of the American
College of Cardiology . Vol. 35, No. 4, pp. 1092-‐9.
Coronary artery disease accounts for 51% of all heart disease, and if no preventaNve
measures are implemented, is projected to cost the naNon $75.8 billion by 2025, up from
$51.9 billion in 1999
Stroke treatment costs are projected to exceed $2 trillion between 2005 and 2050.
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America’s Answer
Spending on prescripNon drugs is projected to grow 3.5% in 2008-‐-‐a slowdown of 1.4% from 2007-‐-‐and
reach $235.4 billion. Drug spending growth is expected to rebound to 4.5% in 2010-‐-‐climbing to
6.6% by 2013. By 2018 it will reach 8.6%. -‐-‐-‐
Sisko, Andrea, Christopher Truffer, Sheila Smith, Sean Keehan, Jonathan Cylus, John A. Poisal, M. Kent Clemens, and Joseph Lizonitz. "
Health Spending ProjecNons Through 2018: Recession Effects Add Uncertainty to the Outlook". Health Affairs
4 Components of Nutrition
GeneNcs Diet
Exercise NutraceuNcals
Genetics
Metabolic rate and needs Cardiovascular anomalies Other systemic diseases Heritage and body type
Diets: An Overview
No carbohydrate Low carbohydrate
High protein Raw foods
Calorie counNng
No Carbohydrate Diets
Less sugar = Less weight Lowest glycemic index diet
Quick weight loss Onen followed by quick weight gain
Not a sustainable lifestyle
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Low Carbohydrate Diet
Less sugar = less weight Steady release of insulin Moderate rate weight loss
Weight gained back at moderate rate Easily sustainable
High Protein Diet
More than 1g/lb. body weight Needs plenty of exercise Needs plenty of hydraNon Not a good long term diet
Recommended for educated athletes
CALORIE COUNTING
Burn more than you consume Time tested
Success levels vary Body weight focus
FOOD Proteins
Carbohydrates Fats
RAW FOODS
Food source in most natural state Diet rich in fruits and vegetables
Healthy fats via nuts PH levels naturally increase Easier to follow due to access
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FATS
Saturated Unsaturated
Trans
Good Fats
raw nuts olive oil fish oil flax seed avocado unsaturated fats
good fats stay fluid in your body and are
proven to be good for you
Bad Fats
saturated fats pork fat
trans fats
bad fats solidify in your body leading to disease
Severe heart attacks linked to bad fat intake
A diet rich in saturated and trans faKy acids increases the risk of severe heart aKacks
Trans Fats
A 1% increase in the porNon of calories from trans fat resulted in a 1.7 pound weight
gain per year.
Harvard Medical School 8 year study of 41,518 woman
Proteins
Helps build muscle Excess turns to fat Taxes the kidneys
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Carbohydrates
Our Main Fuel Source Whole grain foods
Vegetables Fruits Sugar
Increased whole grain consumption linked to better
weight
An increased intake of wholegrain products in the diet may reduce a person's likelihood of
being overweight or obese, suggests a new study from Holland
New study appear to back up the 2005 Dietary Guidelines to Americans recommendaNon to consume at least three wholegrain servings per
day
More support for whole grains for healthy hearts
An increased intake of wholegrain products, in combination with a
reduced calorie diet, led to weight loss and cut levels of a protein associated with heart disease
American Journal of Clinical Nutrition January 2008, Volume 87, Pages 79-90
Whole-grains breakfasts cut heart failure risks
Consuming at least one serving of whole grains cereal a day could reduce a man's
risk of heart failure by 30 per cent Archives of Intern Medicine
Volume 167, Number 19, Pages 2080-‐2085
"Breakfast Cereals and Risk of Heart Failure in the Physicians' Health Study I"
Pinto beans, beans good for your heart
The childhood favorite of 'beans, beans good for your heart' is backed by science,
according to a new study showing that daily consumpNon of pinto beans may cut
cholesterol Journal of Nutri)on
November 2007, Volume 137, Pages 2391-‐2398 "Pinto Bean Consump)on Changes SCFA Profiles in Fecal Fermenta)ons, Bacterial Popula)ons of the Lower Bowel, and Lipid Profiles in Blood of
Humans"
Natural State
Bread Rice Pasta Fruit Beans
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Exercise
Increases heart rate Improves all systems via blood flow
Increases metabolic rate Proven to decrease risks of CVA’s
Increases moNvaNon to stay on course
Bad Case of Lazy Eyes
Couch potatoes are 70% more likely to develop ARMD
Exercise increases endothelial funcNon of blood vessel muscles (peristalsis)
water
suppresses appetite
relieves fluid retention problems reduces sodium buildup in the body
helps to maintain proper muscle tone helps the body metabolize stored fat
rids the body of waste and toxins relieves constipation
drink to your heart’s content
Resistance Training
Weight lining No longer “No Pain, No Gain”
Light weights Start slowly
Full spectrum in gym environment Importance of technique
Greater demand on blood vessels Increases metabolic rate
YOGA Yoga teaches us to cure what need not be endured and endure what cannot be cured.
B.K.S. Iyengar
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The yoga mat is a good place to turn when talk therapy and anNdepressants aren't enough.
Amy Weintraub
Drug Induced Nutrient Depletion What prescribed medicaNons
deplete your body of Average 55 y.o. American is on 3 Rx drugs
Antacids
Vitamin B12 Folic acid Vitamin D Calcium Iron Zinc
AnNbioNcs
B vitamins Vitamin K
Beneficial intesNnal bacteria Calcium
Magnesium Iron
Vitamin B6 Zinc
AnN-‐DiabeNc Drugs
Co-‐Q-‐10 Vitamin B12 Folic acid
AnN-‐Depressants
C0-‐Q-‐10 Vitamin B12
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AnN-‐Inflammatories
Vitamin C Folic acid
Iron Potassium Vitamin D Calcium
Magnesium Selenium
Zinc
Cardiovascular drugs
Vitamin B6 Co-‐Q-‐10 Melatonin
DiureNcs
Vitamin B1 Vitamin B6 Vitamin C Magnesium Calcium Potassium
Zinc Co=Q-‐10 Sodium
Cholesterol lowering agents
Vitamin A Vitamin B12 Vitamin D Vitamin E Vitamin K Co-‐Q-‐10
Beta-‐Carotene Folic acid
Iron
Ulcer MedicaNons
Vitamin B12 Vitamin D Folic acid Calcium Iron Zinc
Protein
HRT
Vitamin B2 Vitamin B6 Vitamin B12 Vitamin C Folic acid
Magnesium Zinc
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Oral ContracepNves
Vitamin B2 Vitamin B3 Vitamin B6 Vitamin B12 Vitamin C Folic acid
Magnesium Selenium
Zinc
Nutraceuticals
Is there a need? Where do I start?
Are there differences in brands? How will I know they’re working?
Why do I need to know this?
Sales of anNoxidant supplements have grown from $2B in 1997 to $3B in 2005 and is now
over $4B
PrevenNon is the best form of treatment
Nutraceuticals
Vitamins Supplements
AnNoxidants – ORAC Oxygen Radical Absorbance Capacity
Nutraceuticals
Substance or groups of substances required for humans to conNnue to live in a healthy state
Water or fat soluble Most need food to accompany them for greater
absorpNon
RDA is just that…a recommendaNon
Supplements for over 50s may boost diet deficiency
Researchers wriNng in the Journal of the American DieteNc AssociaNon found that a substanNal porNon of people over 50 years of age do not get enough vitamins and
minerals from their diet alone and the use of supplements is necessary
Journal of the American Diete)c Associa)on 9/18/2007
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Water Soluble Vitamins
B and C Absorbed directly into bloodstream Readily excreted by the kidneys
Fat Soluble Vitamins
A D E & K Must first enter the lymph system before the
bloodstream May require protein carriers for transport
Not easily excreted by the body Can be toxic in high doses
Vitamin A
Fat soluble Responsible for maintaining proper DNA funcNon
EssenNal for growth and reproducNon Maintaining healthy vision
SupporNng protein synthesis and cell differenNaNon Beta-‐carotene serves as on-‐demand precursor
The B’s
Used in the body individually or in combinaNon with enzymes to help release energy from food sources
Crucial to metabolic pathways that generate energy
Controls Homocysteine*
Vitamin B6 may slash colorectal cancer risk
Increased intake of vitamin B6 from dietary and supplements may
reduce the risk of colorectal cancer by over 20 per cent
Cancer Epidemiology Biomarkers & Prevention
1st January 2008, Volume 17, Pages 171-182
Vitamin C
Scavenges free radicals Protects Nssues from oxidaNve stress
Promotes absorpNon of iron Vital co-‐factor to the formaNon of
collagen
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FDA coming around
FDA approves trial for IV vitamin C for anN-‐cancer therapy
Vitamin C linked to lower stroke risk
Increased blood levels of vitamin C may reduce the risk of stroke by
42 per cent
American Journal of Clinical Nutrition January 2008, Volume 87, Pages 5-7
Vitamin D
Fat soluble Necessary for uNlizaNon of calcium and
phosphorus Acts like a hormone
Sources are organic milk and sunlight
I personally take 6200 iu daily
Fish & Vitamin D Protect Eyes
Omega 3’s and vitamin D may reduce the risk of developing ARMD
Archives of Ophthalmology May 2007
Vitamin D may lower MS risk
Vitamin D lowers risk of mulNple sclerosis by as much as 62% depending on demographics
White adults lowered their risk the most
JAMA Dec 2006
Vitamin D, calcium's colon benefits pinpointed
Epidemiological studies supporting vitamin D and calcium for protection
against colorectal cancer may be biochemically and biologically plausible
2008 American Association for Cancer Research Annual Meeting
13 April 2008
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The E’s
Fat soluble AnNoxidant derived from plants
dL = dead last d-‐alpha tocopherol works well alone
Enhanced funcNon with broad spectrum Blood thinning qualiNes
Tocotrienol may protect against DNA damage
Tocotrienols, the less studied form of vitamin E, may reduce DNA damage, considered an important trigger in cancer
development, by about 50%
Nutri)on (Elsevier) 9/24/2007
Higher vitamin E doses produce better results for heart
Increased doses of vitamin E may produce posiNve results for heart health, says a new study from the US that quesNons the 'under-‐dosing' used in
earlier clinical trials
Free Radical Biology and Medicine July 2007
Vitamin K
Fat soluble Helps keep Calcium in the bones Maintain proper blood vessel flow
Vitamin K linked to fewer varicose veins, better vascular
health
InacNvaNon of a vitamin K-‐dependent protein may contribute to the development of varicose veins,
says a new study that highlights the role of supplementaNon for improving vascular health
Journal of Vascular Research 2007
Vitamin K + Coumadin?
Is it safe?
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Glutathione
Considered by many to be the most important anNoxidant in the body
Low levels have been a contribuNng factor in cataracts, ARMD, OAG and floaters Composed of 3 amino acids
Glycine Cysteine
Glutamic acid
Omega 3 Fatty Acid
Fish Oil AnN-‐inflammatory properNes (DES)
Allows proper blood flow (glaucoma?) Other benefits
Found in cold water marine fish, black currant oil, flaxseed and flaxseed oil as well as
hemp oil
Omega 6 Fatty Acid
Protects cells from degeneraNon Reduces inflammaNon
Found in evening primrose oil, borage oil and black currant oil
Omega 3 to Omega 6 in 3 to 1 raNo
Omega-3 may boost blood vessel elasticity
SupplementaNon with omega-‐3 faKy acids may improve the elasNcity of blood vessels and improve overall cardiovascular health,
reports a new study from China
European Journal of Clinical Nutri)on 9/21/2007
Dosage of Omega 3’s
3500 – 4000mg per day NIH Rx Omacor/Lovaza 4000mg pill
Reliant Pharmaceu)cals
Fish Oil & Dementia
The higher the DHA(docosahexaenoic acid) level, the lower the risk of demenNa and
Alzheimer’s*
Archives of Neurology 11/06
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Omega 3-DHA improves lipid profile
Men with high blood levels of triglycerides, a risk factor for artery hardening, may
benefit from supplements of the omega-‐3 docosahexaenoic acid (DHA)
American Journal of Clinical Nutri)on
August 2007
Fish, Nuts & Olive Oil = ↓ AMD
1 serving of fish per week lowered AMD risk by 31% 1-‐2 servings of raw nuts per week lowered AMD risk by
35% Trans fats was associated with a significant increase in
advancing late stages Olive Oil emerged as protecNve against late stages
Arch of Oph. May, 2009 127(5) 656-‐65
Fish oil boosts bone health
Omega 3 v. Omega 6 supplementaNon
Omega 3 animals demonstrated increased levels of bone formaNon
Nutri)onal Biochemistry June 2007
Anti-cancer support for omega-3
The 2007 study, by researchers from Harvard Medical School and Charité University Medicine, Germany, published in the journal Carcinogenesis, says supplementaNon of omega-‐3 could be more useful at prevenNng colorectal cancer (CRC) than
current drugs
I’ll have some please
Flaxseed, a rich source of plant omega-‐3 and lignans, may reduce the frequency of hot
flashes by almost 60 per cent
Journal of the Society for Integra)ve Oncology July 2007
Maternal omega-3 again linked to children's coordination
Increased intake of the omega-3 DHA during pregnancy could produce improved motor function in the
offspring in later life
The Journal of Pediatrics March 2008, Volume 152, Issue 3, Pages 356-364
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Omega-3 EPA may benefit depressives
Dietary supplements of the omega-3 fatty acid eicosapentaenoic acid (EPA) may
ease symptoms associated with depression
Australian and New Zealand Journal of Psychiatry
07-Apr-2008 Volume 42, Issue 3, Pages 192-198
Coenzyme Q 10
We produce it in our liver Ubiquinone / Ubiquinol Targets the mitochondria
Proper blood flow (glaucoma?) Other benefits
Biotin
Helps the absorpNon of EFAs Good for hair, skin, nails
Bioflavonoids
Neither vitamin or mineral Plant pigment that helps protect the eye
from UV rays QuerceNn and RuNn
Contained in cherries, red onions, red grapes and citrus fruits
Chromium
Helps regulate blood sugar levels Increases circulaNon
Increases fat metabolism Deficiency can cause an increase risk of
floaters eight-‐fold*
Premenopausal Women
Premenopausal women with low Vitamin D levels are at 3 Nmes the risk of developing hypertension compared to women with
normal levels.
American Heart Associa)on’s 63rd High Blood Pressure Research Conference
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Sound Advice
GP exam
Goals and expectaNons
PorNon control
Six small meals Nmed with workout schedule
Sound Advice
Proper carbohydrates Foods consumed in their natural state
Cardiovascular exercise Resistance training NutraceuNcals
Sound Advice
Be educated for your paNent Let your paNents educate you
Keep open mind Subscribe to a newsleKer of choice
Walk the walk Consider BP monitor and digital reNnal camera
Supplements & Cancer Treatment
Why not with chemotherapy? Safe with radiaNon? Pre/Post OperaNve?
Red Meat & Breast Cancer
PosiNve link with estrogen receptor status
Archives of Internal Medicine 11/06 Journal of the Na)onal Cancer Ins)tute 2/2004
Resveratrol Fights Breast Cancer
Resveratrol inhibits cell proliferaNon on many different levels Pharmacology May 2007
Japanese Knotweed Grapes Berries Peanuts
Red wine (Pinot Noir)
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Red wine: Good or not?
Resveratrol
Increases insulin sensiNvity Lowers blood sugar
Enhances cell energy (motochondrial) Improves motor funcNon
Bodom line: Red wine protects you from a high
caloric diet
Run your risk down
Those women with no family history of breast cancer that exercised strenuously
(conNnuous perspiraNon) for 6 hours per week cut their risk of invasive breast cancer
by 31% Archives of Internal Medicine
Folate
Increased consumpNon of folate may reduce the risk of breast cancer by 44 per cent
Sources
fruits and vegetables Grain products
legumes, nuts, and seeds American Journal of Clinical Nutri)on
Volume 86
Green tea may stop colon cancer in its tracks
Green tea may stop the growth of colon tumors in their infancy
Source: Carcinogenesis
Kidney Cancer
Excessive consumpNon of refined carbs can increase your risk of kidney cancer
Interna)onal Journal of Cancer
Wonder about White Bread?
Consuming 4 or more slices of white bread doubles your risk of contracNng kidney
cancer All cancers love sugar (PET scan)
High glycemic index foods increase your body’s insulin producNon
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Cinnamon
Makes insulin more efficient at taking glucose out of your blood and converNng it to fuel in
your body.
Richard Anderson, Ph.D. USDA Human Nutri)on Research Center
Cinnamon again linked to beKer blood sugar
Using cinnamon as a funcNonal ingredient may lead to slower emptying of the stomach and reduce the rise in blood sugar aner eaNng, says a new
study.
American Journal of Clinical Nutri)on June 2007
Pumpkin extract may protect against diabetes
An extract from pumpkin (Cucurbita
ficifolia) may improve blood glucose levels in diabetics, and exert antioxidant effects
Chemistry & Industry
9 July 2007
Canola protein shows anti-diabetes potential
Substituting milk proteins for proteins from rapeseed (canola) could delay the onset of insulin resistance and protect
against diabetes
British Journal of Nutrition 14-Apr-2008
Legumes linked to lower diabetes risk
An increased intake of legumes like peanuts and soybeans could reduce the risk of developing
type-2 diabetes by over 40 per cent
American Journal of Clinical Nutrition
January 2008, Volume 87, Number 1, Pages 162-167
Green Tea
Green tea extract lowers blood sugar and decreases blood lipid levels in diabeNc rats
Hold the boiling water, please
Clinical Exp Pharmacological Physiology dec 2006
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Black tea shows blood sugar benefits
10/24/2007 -‐ A one gram drink of black tea may
have the potenNal to sNmulate an insulin response and reduce blood sugar levels, suggests new research from England
Journal of the American College of Nutri)on Volume 26, Number 5, Pages 471-‐477
"The Effect of Consuming Instant Black Tea on Postprandial Plasma Glucose and Insulin Concentra)ons in Healthy Humans"
Ginseng juice eyed as anti-diabetic dietary supplement
An extract from American ginseng berry may reduce blood sugar levels by 30 per cent and aid weight loss, reports a new study
from the University of Chicago
Nuts about Steak
EaNng walnuts with a meal high in saturated fats may limit damage to your arteries
Journal of the American College of Cardiology
AnNoxidant-‐rich almonds may help in blood sugar control
EaNng almonds can have a significant impact in blunNng the glycemic and insulin
responses of the body when fed with a carbohydrate meal
The Journal of Nutri0on
December 1, 2006
Niacin & Cholesterol
Vitamin B 3 aka nicoNnic acid
Increases HDL by 20-‐35% Decreases LDL by 5-‐25%
Decreases triglycerides by 30%
Extended release is safest and causes limited or no hot flashes Journal of the American College of Cardiology 12/86
Journal of Internal Medicine 8/05
Whole Food Sources Serving Niacin
Organic chicken Wild salmon
Organic turkey Organic peanuts or peanut butter
Grass-fed beef Potato Lentils
Lima beans Whole grain bread
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Soy's cholesterol-lowering mechanism identified
The cholesterol-lowering effects of soy protein may by located in the
liver
Journal of Agricultural and Food Chemistry Volume 55, Number 26, Pages 10599-10604
HTN: I have a headache
Hypertension = ED in men
Hypertensive woman are twice as likely to suffer from low desire and trouble reaching
orgasm
American Society of Hypertension
Pomegranate juice may ease erectile dysfunction
A glass of pomegranate juice every day may help manage erecNle dysfuncNon, suggest
results from a randomized, placebo-‐controlled, double-‐blind, crossover pilot
study
Interna)onal Journal of Impotence Research June 2007
Pomegranate = …pril
Daily consumpNon of pomegranate juice decreases acNvity of angiotensin conver)ng
enzyme (ACE)
Common ACE inhibitors used today are Monopril, Enalapril, Lisinopril, etc…
Results showed the greatest efficacy when consumed immediately following a
meal
Pomegranate Extract
Pomegranate extract significantly reduces the size and number of cancer tumors in mice
Cancer Research April 2007
Onion compound linked to lower blood pressure
QuerceNn, the compound most commonly associated with onions, may reduce blood pressure by an average of five millimeters of
mercury, indicates new research randomized, double-blind, placebo-
controlled study Journal of Nutri)on
November 2007, Volume 137, Pages 2405-‐2411 "Querce)n Reduces Blood Pressure in Hypertensive Subjects"
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Apples and onions may slash pancreatic cancer risk
A diet rich in flavonols from foods such as onions, apples and berries may cut the risk of developing pancreaNc cancer by about
25 per cent American Journal of Epidemiology 10/1/2007
Lose weight=Lower risk of prostate cancer
Men that lost more than 11 pounds in the decade long study reduced their prostate
cancer risk by 40% Cancer Epidemiology Biomarkers
American Cancer Society
Study backs lycopene against advanced prostate cancer
Increased blood levels of lycopene may reduce the risk of advanced prostate cancer
by 60 per cent
American Journal of Clinical Nutri)on 9/21/2007
Vitamin E ↑ Prostate Cancer Survival
Those study parNcipants that were in the top finh percenNle of Vitamin E levels had a
33% lower risk of dying
Cancer Research May 2009
Broccoli and cauliflower may slash prostate cancer risk
EaNng more than one serving of broccoli and cauliflower a week may reduce the risk of
prostate cancer by up to 45 per cent
Journal of the Na)onal Cancer Ins)tute
Green tea spurs detox chemical production
A new clinical study provided evidence that green tea catechins can sNmulate
producNon of cancer-‐protecNve enzymes in people with low natural levels -‐ the first to demonstrate this effect in humans, say
researchers
Cancer Epidemiology Biomarkers & Preven)on August 2007
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Cocoa-rich diet may boost thymus antioxidant defenses
A diet rich in cocoa flavonoids could boost one's
anNoxidant defenses, parNcularly in the thymus The thymus sNmulates the producNon of certain infecNon-‐fighNng cells. It is of central importance
in the maturaNon of T cells
Journal of Agricultural and Food Chemistry August 2007
Citrus flavanones show neuroprotection potential
Antioxidant compounds in citrus fruit may have a role to play in
protection against neurodegenerative diseases
Journal of Agricultural and Food Chemistry
21/1/2008
Probiotics may offer benefits for alcoholic livers
Supplements of friendly bacteria may restore the immune function of white
blood cells in alcoholics
Journal of Hepatology (Elsevier) 25 March 2008
Lutein, zeaxanthin, vitamin E eyed for cataracts
A higher intake of the carotenoids lutein and zeaxanthin, as well as
vitamin E, could reduce the risk of developing cataracts by about 15 per
cent Archives of Ophthalmology
January 2008, Volume 126, Issue 1, Pages 102-109
Soy isoflavones linked to easier breathing
Four weeks of supplementation with genistein, an isoflavone from soy, may suppress the inflammatory process and ease breathing and
explain previous reports linking the isoflavone to reduced asthma
severity Clinical & Experimental Allergy
January 2008, Volume 38, Issue 1, Pages 103-112
Soy linked to less belly fat in postmenopausal women
A daily soy supplement may prevent abdominal fat increases in post-
menopausal women
Fertility and Sterility (Elsevier)
December 2007, Volume 88, Issue 6, Pages 1609-1617
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Young women's bones also benefit from soy
Habitual consumption of soybeans and isoflavones may increase bone mineral density in young women
Nutrition Research (Elsevier)
Volume 28, Issue 1, January 2008, Pages 25-30
Soy products + Breast Canser
The jury is in! (for now)
Zeaxanthin linked to better mental performance in the
elderly
Increased intake of the carotenoids lycopene and zeaxanthin may improve the mental
performance of the elderly
Journal of Gerontology: Medical Sciences
Blueberry flavonoids could have Alzheimer's
benefits
Blueberries and other phytochemical-rich foods could help in increasing memory
capacity by reversing age-related deficits in memory
Free Radical Biology and Medicine11-Apr-2008
Green tea for sports nutrition
Antioxidant-rich green tea may counter the effects of resistance exercise by reducing the detrimental effects of
oxidative stress Nutrition (Elsevier)
May 2008, Volume 24, Issue 5, Pages 433-442
Eating Disorders
Anorexia Nervosa – unable or unwilling to maintain normal body weight
Bulimia Nervosa – Binge eaNng followed by purging techniques
Binge EaNng – onen associated with obesity aka food addicNon
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OD Diagnosing Eating Disorders?
Punctate Keratopathy Primary VasospasNc Syndrome-‐engorged conj vessels, K edema BRVO/CRVO, AION & OAG
Severe DES with ulceraNons
10 Important Blood Tests
CBC FIBRINOGEN HEM A1C DHEA
PSA-‐ PROSTATE SPECIFIC ANTIGEN
HOMOCYSTEINE C-‐REACTIVE PROTEIN TSH-‐THYROID STIMULATING HORMONE
FREE TESTOSTERONE ESTRADIOL
Complete Blood Count
Best overall status report Checks:
Vascular kidney liver blood cells
Fibrinogen
An important contributor to blood clo�ng
High levels are associated with:
Heart disease rheumatoid arthriNs GlomerulonephriNs (inflammaNon of the kidney)
Hemoglobin A1C
Measures a person’s blood sugar control over the last 2-‐3 months
Long-‐term elevaNon is associated with increased risk of heart disease and stroke Chromium, cinnamon and coffee berry extracts help opNmize Hem A1C levels
DHEA
Hormone produced by the adrenal glands Precursor to the sex hormones testosterone and
estrogen Peaks in our 20’s / 20% len by age 80
Supports: Immune system bone density mood libido
healthy body composiNon
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PSA-Prostate Specific Antigen
A protein manufactured by the prostate Elevated levels suggest:
enlarged prostate prostate inflammaNon prostate cancer
May also be used as an indicator for treatment efficacy
Homocysteine
Amino acid formed in the body
High levels associated with: Heart disease/aKacks bone fractures
decreased cogniNve funcNon
C-Reactive Protein
SensiNve marker for systemic inflammaNon
Increased levels associated with: Heart disease diabetes
macular degeneraNon cogniNve decline
Thyroid Stimulating Hormone
Secreted by the pituitary gland, TSH controls thyroid hormone secreNon
Low levels associated with: FaNgue depression cold intolerance dry skin/
mouth/eyes consNpaNon weigh gain
High levels associated with: Weight loss heat intolerance muscle weakness shortness of
breath heart palpitaNons
Free Testosterone
Produced in the testes, ovaries and adrenal glands Less than 2 % typically found in men/women
Unlike bound form, free testosterone can circulate in the brain and effect nerve cells
Low levels in men: Abdominal obesity depression osteoporosis
heart disease Low levels in women:
Decreased libido & well being
Estradiol
Primary circulaNng form of estrogen in men/women
Low levels in women: Decreased bone density increased menopausal
symptoms (hot flashes, irritability & insomnia)
Low levels in men: Increased vertebral fractures osteoporosis skeletal
frailty
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Miracle Cure
Increases
Vital hormone secreNons including sexual potency and ferNlity
Rates of digesNon, metabolism and excreNon
Quality of sleep Awareness and mental faciliNes Mood stabilizaNon Flex of the diaphragm increasing
lung capacity and O2 rates
Decreases
Respiratory rate slowing down respiratory paKerns
Breaths needed per minute Pulse rate by 10-‐15%
Hint-some of you are doing it right now
• Deep breathing
We’re not all the same
What do I eat
What do I take
Some Sources
www.MedOp.com www.FeelMoreAliveNow.com
www.DrSinatra.com
www.DrStevenNewman.com