october 2012 - esco · nowadays, couples struggling with infertility have more and more options to...

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www.escoglobal.com

02 CEO letter03 The New Esco Technology Centre 04 Inside the Facility05 New Products07 New Lowest Noise BSC In The World08 Winning the Big Orders09 Esco’s Global Stocking Locations10 Esco on the Scene

Pictured: Esco's state-of-the-art manufacturing facility

Esco News | October 2012

Building on Esco’s tradition of producing quality laboratory equipment for the global scientific community, the Miri® is the ONLY multi-room incubator in the market featuring a combination of the following:

• Mixed gas NOT required = reduced operating costs• Heating in the lid • Documented UVC decontamination of recirculated gas• MEA tested and documented• 12 x PID regulation system, the most advanced in the world• Built-in temperature validation• Full parameter display visible at a distance• Pressure sensors on external gas

THE LATEST INESCO’S SUITE OFPRODUCTS FOR

IVF LABORATORY

Esco Micro Pte. Ltd. 21 Changi South Street 1 • Singapore 486 777Tel +65 6542 0833 • Fax +65 6542 6920 • [email protected]

Esco Global Offices | Manama, Bahrain | Beijing, China | Chengdu, China | Guangzhou, China Shanghai, China | Bangalore, India | Delhi, India | Mumbai, India | Banten, Indonesia | Osaka, Japan Kuala Lumpur, Malaysia | Melaka, Malaysia | Manila, Philippines | Singapore | Seoul, South Korea Salisbury, UK | Philadelphia, PA, USA | Hanoi, Vietnam

Multi-room CO2 incubator for IVFMiri®

EU MDD Class IIa Medical Device tested and certified!


CEO Letter

Dear Valued Partners,

Although 2012 has been a turbulent year for the global economy, the Esco Group has continued to invest in our sales & service infrastructure, manufacturing capabilities, and new product development.

The Esco Group of Companies is today a global life sciences tools provider with sales in over 100 countries. The group is active in lab equipment, pharma equipment and medical devices. Manufacturing facilities are located in Asia and Europe. R&D is conducted worldwide spanning the US, Europe and Asia. Sales, service and marketing subsidiaries are located in 12 major markets including the US, UK, Singapore, Japan, China and India. Regional distribution centers are located in the US, UK, and Singapore.

In our laboratory equipment business, we are reaping the fruits of our investment in new product development over the last few years. In addition to a world leading portfolio of biological safety cabinets and fume hoods, Esco today manufactures a complete portfolio of temperature controlled equipment, including CO2 incubators and ultra-low temperature freezers.

In our pharmaceutical equipment business, we have secured a few key project wins for isolation systems building on our core engineering competence, Asian manufacturing and proximity to Asian pharmaceutical customers.

In our new medical equipment division, we have launched the first of a complete suite of equipment for the ART/IVF laboratory. The Esco Miri®, manufactured at a new site in the EU, is the first EU Class IIA certified multi-room incubator on the market.

Regionally, we continue to pursue strategic initiatives to expand our business in the Americas, Europe and Asia Pacific. We are focused on growing our sales, marketing and service teams in all 3 geographies.

We are investing in our UK site as a regional base to further expand and develop our European business. Regional positions and warehousing facilities have been added in order to support this initiative.

In Asia, we are investing in our businesses in China, Southeast Asia and Japan. In Aug 2012, we created a Center of Excellence to expand our product development efforts in Shanghai. In Southeast Asia, our core market, we have incorporated subsidiary companies in the Philippines and Indonesia. We incorporated a subsidiary company in Japan in early 2012.

We are also pursuing frontier markets with the incorporation of Esco South Africa earlier this year.

We have also continued to strengthen our core product offering, biological safety cabinets, and have won multiple large new construction bids in the US, Europe and Asia in this category.

As we enter the last quarter of 2012 and begin planning for 2013, I would like to once again thank all Esco team members, suppliers, distributors and business partners for your continued support.

Sincerely,

XQ Lin

Group CEO

Lin Xiang Qian, CEO

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Esco Medical® : A Rising Star on the Horizon of the Medical / IVF Industry by: Joseph Angelo Uichanco - Application Specialist, Esco Medical

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Nowadays, couples struggling with infertility have more and more options to be able to have a baby. Most notable of these is in vitro fertilization (IVF). Currently, IVF is a growing industry as more and more people gain access to doctors and clinics that offer fertility treatments that include the latest artificial reproductive technologies (ART).

Infertility is defined as the inability of a heterosexual couple to get pregnant after 1 year of regular attempts to conceive. It is a sensitive problem and it impacts the affected individuals on many levels. Indeed, it brings with it economic, psychological, and social consequences. Moreover, low birth rates are an issue for many.

In vitro fertilization is a highly specialized medical procedure. Briefly, it involves harvesting gametes from the male and female, combining these in the lab, incubating the embryo, and then transferring the embryo to the uterus to progress to full-term pregnancy. IVF, consequently, involves highly specialized trained practitioners and likewise, highly specialized protocols and equipment. To date, thousands of children have already been born since the first IVF baby was born in the 1970s.

The Esco Group of Companies realizes the importance of reproductive health and the importance of reinvigorating the IVF technological market with state-of-the-art and cutting-edge innovation. The company, through Lin Xiang Qian, Esco Group of Companies CEO, recognizes this furthermore as an opportunity to transfer its long-standing expertise in laboratory equipment, clean air, and isothermal technologies to the IVF market. The result is the birth of Esco Medical.

Esco Medical is in large part the brainchild of the acquisition of Thomas Pedersen’s expertise in meeting the exacting requirements of IVF laboratories and clinics. Thomas Pedersen is the EVP for innovation at Esco Medical and here, he leads the development of the product line of IVF laboratory solutions under the brand name. Currently, Esco Medical offers IVF workstations, conventional CO

2 incubators, and benchtop incubators. The Miri® is Launched at ESHRE 2012

While the Esco Medical brand name is relatively new in the IVF market, the new Esco Miri Multi-room Incubator for IVF sets the tone as an impressive introductory product at the recently concluded meeting of the European Society of Human Reproduction and Embryology (ESHRE) in Istanbul, Turkey. The Esco Medical team, composed of XQ Lin, Esco Group CEO; Thomas Pedersen, EVP for Innovation; Joseph Uichanco, Application Specialist; and Owais Yaqub, Regional Manager for MENA, was present and introduced the product line which included the Miri.


The Miri’s reception was very positive. As a benchtop multi-room incubator for IVF, it meets all the requirements expected by the inquiring IVF experts---embryologists, clinicians, and other IVF specialists---who visited the Esco Medical exhibit booth. Miri was described as an exceptionally designed product that allowsusers to use pure gas to control CO2 and O2 concentration, has a full-range of temperature and gas control and validation features, 6 completely isolated chambers, and so much more.

The Miri also boasts extensive certification such as CE markingas an EU MDD Class IIa Medical Device and IEC/EN 60601-1 (3rd edition). Also exhibited at the Esco Medical booth were the Labculture® IVF Workstation and CelCulture® conventional CO2 incubator with Suppressed O2 for IVF.

The governing principle behind the current (and future) products of Esco Medical is that of the Silent Embryo Hypothesis. The hypothesis is that the less disturbed or less stressed cultured embryos are, the less active their metabolism is. Ultimately, this low level metabolic activity means that the embryo does not expend energy to address any stressors or damage and thus maximizes developmental potential of the embryo to progress into a healthy pregnancy. Some common stressors that might be introduced during embryo culture include temperature and gas concentration fluctuation, non-optimal pH levels of the growth medium, biological contaminants, and volatile organic compounds (VOCs).

The current lineup of Esco Medical products are all designed around the aim of minimizing negative issues relating to embryo culture and manipulation. For example, the CO2

incubator employs a high-performance ULPA filter that provides clean air to circulate to the cultures. Suppressed O2 models also allow for provision of lowered oxygen concentrations; recent studies have highlighted the benefit of controlling the oxygen in incubators to around 5% O2.

The new Miri benchtop incubator furthermore builds on these as it is multi-chambered with smaller effective volumes that minimize or totally prevent temperature and gas concentration fluctuation that usually occurs when the incubator door is opened and cultures are accessed. To that effect, Miri can demonstrate fast recovery of the said culture conditions.

Beyond embryo incubation, embryos and other related biological samples sometimes need to be manipulated. The Labculture IVF Workstations is offered as an ideal solution to provide a sterile work environment with a work surface warmed to physiological temperature. The concept then is a complete setup to be able to perform manipulation while minimizing temperature disruptions to the biological material such as temperature-sensitive embryos in culture. The workstation can further be customized with other relevant features such as integration of microscopes and LCD monitors.

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The temperature-controlled line of equipment is currently Esco’s fastest growing product line, with new products, models, or options launched every quarter. A good number of ULT freezers, CO2 incubators, refrigerated incubators, and general purpose ovens and incubators have been sold and installed all over the world. Now, Esco is providing more options to customers for these world class products.

A stainless steel exterior on laboratory equipment means having a robust construction and a corrosion-resistant surface. This

option is now possible for the Isotherm® Forced Convection Laboratory Ovens and Incubators. Stainless steel exteriors help to meet pharmaceutical and clinical laboratory requirements.

Copper interior option is now available for the CelCulture CO2 incubator. With its anti-microbial properties we’ve known for hundreds of years, 100% pure copper interiors, including copper shelves, offer additional protection for your precious samples. The CelCulture now comes in 3 sizes: 50L, 170L, and 240L.

More Choices with Esco’s Temperature-controlled Products


In April of this year, Esco introduced the Lexicon Ultra-low Temperature Freezer U-Series available in different sizes. To help you choose the freezer you want, here is a guideline for the ordering code.

U-Series

UUS-439B-1

UUS-552B-1

UUS-668B-1

UUS-793B-1

Lexicon ULT Freezers for Sushi RestaurantsAbout 3 months ago, Esco GB received an inquiry for a -86 freezer from someone who is setting up a sushi restaurant. According to him, they require to store fish at this temperature to prevent deterioration and the fish would remain fresh when thawed and cut up, better than normal freezers. Esco GB offered the Lexicon UUS-668A-1 with the S-series controller. Who knows? This could be another new industry for Esco Lexicon ULT Freezers.


PT Esco Utama is OpenEsco had opened its new office in Indonesia, PT Esco Utama, and began operations from their office in Tangerang last July 2. Esco Utama will provide a full range of services to customers in Indonesia, including sales of Esco’s entire product range, servicing of equipment, and providing customer service and technical support. This will be supported by its staff consisting of sales, service, and finance.

PT. Esco UtamaTaman Tekno BSD Blok G3 no.5 BSDSektor IX Serpong, Tangerang 15314Phone: +62-21-75881897Fax: +62-21-75881939

Camfil Farr is Now Esco’s Exclusive Distributor in New ZealandWe are pleased to announce the appointment of Camfil Farr NZ as our new exclusive distributor in New Zealand. Camfil has significant experience of biohazard containment and clean air filtration in labs and industries. Not only can Camfil service, test and commission laminar airflow cabinets, they are also the world leaders in providing quality ULPA filters used in these equipment. Having been trained at Esco’s factory, Camfil NZ can provide sales and technical support for our full range of equipment which includes biological safety cabinets, pharmacy isolators, cleanroom equipment, ovens and incubators, CO2 incubators and Ultra Low Temperature freezers.

‘Our unique position adds extra value for our customer. We understand air-filtration and with this knowledge we can provide the customer with a total supply package incorporating the air-supply systems and maintenance, Esco equipment and final testing and certification for most applications’ - John Brock, General Manager.

Camfil Farr New Zealand is the market’s premier filtration provider with a focus on Clean Air Solutions. Camfil’s range encompasses a vast range of Air-filter products, Dust and Fume collection systems, Odor and gas Control, Clean-air testing and Service. Their Clean Air-testing division has a long history of providing companies with specialist services. The Technical staff is NZ accredited for Clean-air testing and service, this enables Camfil to prove their performance claims. With offices in more than 50 countries and manufacturing plants close to the customer, Camfil is the leading Clean Air Solutions Company.


Esco EventsThe first 3 quarters of the year has already gone by and a lot has transpired over the past months. From exhibitions to sales meetings to end-user seminars, Esco’s global presence continues to grow with the different events and activities undertaken, all of which are essential in building good business relationships between Esco and all its stakeholders.

ANALYTICA 2012 - GERMANY

The Analytica 2012 exhibition in Germany kicked off the stream of international events for the second quarter of the year. The exhibition, which took place in Munich, is held every 2 years and is probably one of the most important shows for laboratory equipment. Here, Esco introduced the eSafe® Microbiological Safety Cabinet (still in prototype stage), a new, state-of-the-art cabinet, which is both energy-efficient and ergonomic, with ECM blowers, low noise level, enlarged display, and an efficientsize for ease of placement in laboratories.

CETA 2012 ANNUAL MEETING - USA

Esco Technologies, Inc. (ETI) took part in the CETA 2012 Annual Meeting, where ETI exhibited the Isoclean® Compounding Aseptic Isolator, HPI-P model, in one of the 30 booths at the show. About 200 certifiers were in attendance as well as controlled environment testing professionals and other manufacturers of BSCs and fume hoods. ETI conducted a series of electrical troubleshooting sessions which received plenty of positive feedback from certifiers. The CETA 2012 examined wide-ranging issues affecting the controlled environment.

DISTRIBUTORS’ PRODUCTS AND SERVICETRAINING - SINGAPORE

The annual Distributors’ Products/Sales and Service Training was held on May 16-25 in Singapore. The products training focused on new BSC models, thermostatic products updates, and PCR thermal cyclers as well as a short refresher on laminar flows, animal handling workstations, and IVF equipment. As in the

previous years, a distributors’ appreciation dinner took place onthe second evening of the training. The products training ended on Saturday, 18 May, with a short factory tour at the new Esco Technology Centre. The service training followed the week after with 16 participants, most of whom attended such training with Esco for the first time and were pleased to have gained more knowledge on troubleshooting and advanced servicing of Esco products.


1ST ANNUAL SALES MEETING - USA

ETI held its first annual sales meeting last June 12-13, 2012. Over 20 sales representatives from across the United States attended. While product training was the main focus of the meeting, representatives learned quite a bit about the history of the company and the many industries that utilize our products. Everyone gathered for an appreciation dinner Tuesday evening where they were able to get to know each other on a more personal basis and put faces with the names they hear and speak to so often. ETI hopes that everyone gained a wealth ofknowledge as to how our products compare to those of other manufacturers and why Esco Technologies products are quickly becoming a leader of innovation in the industry.

ACHEMA WORLD EXHIBITION CONGRESS -GERMANY

Another one of the largest exhibitions in Europe, the ACHEMA World Exhibition Congress, was held on June 18-22 in Frankfurt, Germany. ACHEMA is a world forum for chemical engineering and the process industry. Esco was one of the exhibitors who had the opportunity to meet with its existing partners in Europe and other countries, as well as show off some of its best products. Potential partners also visited the booth. One of the highlights of ACHEMA for Esco was the distributor meeting and dinner held on the 3rd day of the event. The ACHEMA Exhibition occurs every 3 years.

P-MEC – CHINA

Last June 26-28, the Pharmaceutical Machinery & Equipment Convention or P-MEC was held in Shanghai, China, which gave visitors from all over the world the opportunity to meet more than 300 Chinese and international suppliers of pharmaceutical machinery and equipment. P-MEC became an avenue for Esco to launch its new pharmaceutical equipment such as the sterility test isolator, weighing dispense containment isolator, and other lab equipment. Esco received an excellent response and the launch was a complete success for Esco’s pharmaceutical division.


END-USER SEMINARS – LAOS AND MYANMAR

End-user seminars are one of Esco’s ways of serving its customers and helping to promote safety awareness and best practices in the laboratory, especially when working with equipment such as Esco’s products. Two end-user seminars were conducted last April and May in Laos and Myanmar, respectively.

Despite being a small country, Laos shows huge potential with a lot of areas to be explored. Thanks to the support of our distributor, Europ Continents, Esco was able to organize a seminar on April 4-5 at the Pasteur Institute in Vientiane, the capital of Laos. Pasteur Institute is one of the biggest customers in Laos and this seminar serves as a good break for Esco in the country.

Due to the very good response to the seminar invitation, Esco had to allot 2 days for Myanmar in order to accommodate the huge number of interested end-users. The first session was held on May 10 at Panda Hotel where there was a mix of about 80 participants from the private sector, fish government, OBVC, and other institutions. The second batch of attendees was from the Department of Medical Research where about 60 people were in attendance from the government sector. This session was held the following day, May 11. Thanks to our partner in Myanmar, Nanova, for helping us to organize this event and made it a success.

Esco Offers Hydrogen Peroxide Decon in SingaporeDecontamination of biological safety cabinets is needed for a safer and efficient working process for users as well as to protect samples from contamination. The most common decontamination method is by fumigation with formaldehyde gas. In some countries, however, formaldehyde is banned. Instead, decontamination is done using chlorine dioxide or hydrogen peroxide. Esco now offers decontamination service using Bioquell EBDS Hydrogen Peroxide Vaporizer, which is an environmentally-friendly alternative to formaldehyde gas.

Hydrogen Peroxide or H2O2 decontamination is performed by flash vaporization of an aqueous peroxide mixture, creating a vapor that is distributed throughout the inside of the biosafety cabinet. H2O2 vapor is non-carcinogenic but highly effective against microorganisms. It breaks down under

catalytic action to become air and water, making it safe for the environment and leaving no residue.

Other updates:

• Analis represents Esco for Lexicon Ultra-low Temperature Freezers in Belgium• Esco Technologies in South Africa now covers the following neighboring countries: Botswana, Lesotho, Malawi, Swaziland, Zambia, Zambia, and Zimbabwe.

Esco’s New Staff Appointments

Esco is pleased to announce the new appointments for 2 of Esco’s staff, Olga Nelson of Esco Technologies, Inc. USA and Andiyanto Sutandar of Esco Micro Pte Ltd, Singapore headquarters.

Olga Nelson has been promoted to Director of Operations for Esco Technologies, Inc., USA. In this new appointment, Olga oversees and manages all aspects of the company, which includes, but not limited to, financial management, logistics, procurement, sales and marketing. Olga, originally from Ukraine, migrated to the US in 2004. She earned her Bachelor’s Degree in Linguistics and Philology in Kiev, Ukraine, and went on to complete her Master’s degree in Accounting in New Hampshire. She has 5 years experience in office management before joining Olga Nelson of ETI Andiyanto Sutandar of Esco Micro


ETI. She began working with ETI in 2007 as office manager, responsible for inventory, financial reports, purchasing, sales management, administration, and other duties. She was promoted in 2008 to Operations Manager and took on more responsibilities.

Esco has appointed Andiyanto Sutandar as Product Manager for Biosafety and Laminar Flow Cabinets. Andiyanto, or Andi, is an Indonesian living in Singapore since 1998. He graduated with a degree in Mechanical and Production Engineering from a university in Singapore. He continued to do research

in microbiology leading to a Doctorate degree from the same university.

Prior to joining Esco, Andi managed and delivered biorisk (biosafety and biosecurity) consultancy services for organizations handling biological materials. He has visited and worked with some of the major containment laboratories in the world. His experiences include areas such as risk assessment, commissioning and certification. In addition, he has experience in developing biosafety and infection control training materials.

In an effort to excel in both quality and quantity of its products, Esco has a passion for never-ending improvement and welcoming hands towards high-end technologies. Equipped with the latest laser, punching, bending, and shearing technology, Esco will always strive to fulfill any customer’s requirement with on-time delivery.

With the arrival of the new AMADA HD1303NT Bending machine which was deployed in our lineup of production machines on 29th of March 2012, our production facility has gained a boost in both quality and quantity of output. This huge bison of the processing department has the capacity of 130 tonnage which enables it to bend up to 6 mm thickness of stainless steel sheets and complemented with the automatic BI-S Automatic Angle Sensors that offers ease of operation in getting the desired bending angle.

Regardless of its huge appearance, this machine is surprisingly eco-friendly, with 50% power savings and 60% less hydraulic oil requirement compared to its predecessors. In short, this machine is capable of bending any Esco product parts and it is a very suitable arsenal for a high-productivity manufacturing facility like Esco’s.

New Bending Machine in Esco Technology Centre

Camfil Farr is Esco’s authorized representative in Australia. Earlier this year, they were chosen to supply Esco Class II Biological Safety Cabinets to the Queensland Institute of Medical Research (QIMR). This order, according to Camfil Farr, is the largest they have ever received in Australia.

QIMR is one of the country’s largest and most successful medical research institutes, with more than 700 scientists, students and support staff in six research departments spread over 50 different laboratories. QIMR was established to facilitate further studies on tropical diseases in North Queensland but have later expanded its research to include the genetic and environmental influences of a range of diseases.

Esco BSCs at the Queensland Institute of Medical Research, Australia

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Esco GB was chosen to supply four Frontier Acela Fume Hoods and two Frontier AcelaTM Floor Mounted Fume Hoods to Solid Form Solutions. The units were successfully installed in April, within the client’s specified target schedule for completion. Esco GB engineers worked in parallel with the ventilation contractors to deliver, fully install, commission, and integrate all units within 32 hours on site.

Solid Form Solutions provides Solid State Contract Research Services to the pharmaceutical industry. After establishing a high quality solid-state screening service, Solid Form Solutions Ltd soon expanded into the process development arena, which has seen the company provide the backbone to several successful manufacturing campaigns. The installation of the 6 Acela fume hoods was a part of this expansion.

Esco GB Supplies Acela Fume Hoods to Solid Form Solutions, UK

In Chile, the Ministry of Fuel, Energy, and Electricity has transformed a shipping container into a mobile laboratory. Arquimed, Esco’s distributor in Chile, supplied the entire laboratory set-up, including an Esco 4ft Frontier JuniorTM Fume Hood. The mobile laboratory will be used to monitor contamination and adulteration of fuel, diesel, and petrol used on buses, petrol stations, aviation, and other related uses.

Frontier Fume Hood Installed in a Shipping Container Turned Laboratory, Chile

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Meet Esco at the following events:

LAB Africa 2012Date of Event: 2012-10-11 Until 2012-10-12Location: Durban Exhibition Centre, South Africa

Analytica ChinaDate of Event: 2012-10-16 Until 2012-10-18Location: Shanghai, China

68th ASRM Annual MeetingDate of Event: 2012-10-20 Until 2012-10-24Location: San Diego, California

Medi-Pharm Expo in Hanoi 2012Date of Event: 2012-12-05 Until 2012-12-08Location: Hanoi, Vietnam___________________________________

Esco News is the online publication of Esco Microfor Esco customers, partners, suppliers and team members.

Published by:Esco Micro Pte. Ltd.21 Changi South Street 1, Singapore 486777Phone: +65 6542 0833Fax: +65 6542 6920Email: [email protected]: www.escoglobal.com

Editor / WriterAngel FloresEsco Micro Pte [email protected]

Layout Artist:Abel de RamonEsco Micro Pte [email protected]

october 2012 - esco · nowadays, couples struggling with infertility have more and more options to...

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