ofclinical pathologytelephone numbers: 0171 383 6209/6154. fax number: 0171 383 6668. they should be...
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JePJOURNALOF CLINICALPATHOLOGYThe journal of the Association of Clinical Pathologists: A Registered Charity
Editor: David LoweAssistant Editor: Helen HolzelTechnical Editor: Andrea HorganEditorial Assistant: Mavis BurrellBMA House, Tavistock Square, London WC1H 9JR; Tel 0171 383 6209
EDITORIALBOAJRD
AL AppletonCC BirdAW BoylstonD BurnettJ Crocker
JD DaviesFV FlynnDJ GoldieJHE HayekFD Lee
JS LilleymanAJ MalcolmJH McCarthyRN PeelMD Penney
RS PereiraGL RidgwayC RobertsDN SlaterRC Spencer
Former Editors
Association ofClinical Pathologists
AG Signy 1944-72 HEM Kay 1972-80 G Slavin 1978-88 J Iilleyman 1986-92
President: Dr WR Timperley; President-Elect: Dr PM Emerson; Vice-Presidents: Dr PJ Fitzpatrick, Dr JD Davies;Chairman ofCouncil: Dr DM Harris; Honorary Secretary: Dr AJ Malcolm; Honorary Treasurer: Dr AC Ames; GeneralSecretary: Mrs JS Tumer, 221 Preston Road, Brighton BN1 6SA; Tel: (01273)561188; Fax: (01273) 541227
Cover illustration:
Visualisation ofimmunoglobulin genes byfluorescence in situhybridisation inphytohaemagglutininstimulated lymphocytes.Triple labelling for interphasenucleus withdiaminophenylindol (DAPI)(blue), a painting library forchromosome 22 (red), and aplasmid Ck probe (green).(See: Carvalho et al. In situvisualisation ofimmunoglobulin genes innormal and malignantlymphoid cells. Y Clin Pathol:MolPathol 1995;48:M1 58-64.)
Published by BMJ
Publishing Group andprinted in England byLatimer Trend & Co.,Plymouth
Information for Authors
Papers should be sent in duplicate to the Editors,Journal of Clinical Pathology, BMJ Publishing Group,BMA House, Tavistock Square, London WC1H 9JR.Telephone numbers: 0171 383 6209/6154. Fax number:0171 383 6668. They should be typewritten with doublespacing on one side of the paper only. The names of theauthors with initials or one forename should be followedby the name of the institution where the work was per-formed. An indication of the position held by each authormust be given in an accompanying letter to the Editors,and this should include the signatures of all authors onpapers with joint authorship. Guidelines on authorship aredetailed in Clin Pathol 1986;39:110. Results should notbe shown as both tables and graphs, and histograms shouldnot be used where tabular information would be moreappropriate.ARTICLES Papers should usually be no more than 2000words long and should report original research of relevanceto the understanding and practice of clinical pathology.They should be written in the standard format with astructured abstract. The abstract should contain the head-ings Aims, Methods, Results and Conclusions and be no morethan 250 words long. The body of the paper should haveseparate sections for the introduction, the methods and theresults, and the discussion. If statistics are used the methodsand confidence intervals should be stated. Authors areurged to seek expert advice if in doubt. Revised manuscriptsshould be submitted as hard copy and on disk. Detailedinstructions will be sent to authors on invitation to revise.Occasional Articles have a less rigid format, being 1500-2000 words in length. They are usually invited by theeditors, though unsolicited submissions will be considered.Single case reports and briefpapers (such as those describingnegative findings) will usually be considered only as ShortReports. The format for these is an unstructured 150 wordsummary, up to 1500 words of text, up to two tables or
figures (or one of each) and no more than 10 references.Letters to the Editor should normally refer to previouslypublished papers or make some point about the practice ofpathology. They are not intended to be a vehicle for thepresentation ofnew data unrelated to earlierJournal articles.
ACKNOWLEDGMENT OF RECEIPT A stamped addressed post-card should be enclosed for return to the author as ack-nowledgment ofreceipt ofthe manuscript. Overseas authorsshould enclose intemational reply paid coupons.
ETHICS The critical assessment of papers submitted willinclude ethical considerations.
ILLUSTRATIONS Diagrams should be reproduced photo-graphically. The legends for illustrations should be typedwith double spacing on a separate sheet. Photographsand photomicrographs must be of high quality in fulltonal scale on glossy paper, and unmounted. Onlysalient detail should be included. Areas without tissue("background") should be as near white as possible.The width of illustrations should be 6-7 cm, 10-2 cm,
13-7 cm or, in exceptional circumstances, 17-4 cm, tofit the column layout of the Journal. Colour reproductionis welcomed and is subsidised by the Journal; for detailsof costs to the author please contact the Journal office.ABBREVIATIONS Abbreviations must be spelt out on firstuse or be accompanied by explanation in the text. The useof non-standard abbreviations and acronyms should beavoided.Symbols and abbreviations should be in the Vancouverstyle.uNIrs All measurements should be given in SI units.REFERENCES The references must be given in the Van-couver style.REPRINTS These may be ordered when the proof is re-turned. Prices for large numbers of reprints available onrequest.
NOTICE TO ADVERTISERS Applications for advertisementspace and for rates should be addressed to the Ad-vertisement Manager, Journal of Clinical Pathology, BMJPublishing Group, BMA House, Tavistock Square, LondonWC1H 9JR.The J'ournal of Clinical Pathology is published monthly.The annual subscription rates (including Clinical MolecularPathology) are £278.00; USA $436.00. Orders should besent to The Subscription Manager, Journal ofClinical Patho-logy, BMJ Publishing Group, BMA House, TavistockSquare, London WC1H 9JR. Subscribers may pay for theirsubscriptions by Access, Visa, or American Express, byquoting on their order the credit or charge card preferred,together with the appropriate personal account number andexpiry date of the card. Orders can also be placed with anyleading subscription agent or bookseller. (For the con-venience of readers in the USA subscription orders, withor without payment, may also be sent to the British MedicalJournal, Box 408, Franklin, MA 02038, USA. All enquiries,however, must be addressed to the publisher in London.)All enquiries regarding air mail rates and single copiesalready published should be addressed to the publisher inLondon.
COPYRIGHT 1995 Journal of Clinical Pathology. Thispublication is copyright under the Berne Convention andthe Intemational Copyright Convention. All rights reserved.Apart from any relaxations permitted under national copy-right laws, no part of this publication may be reproduced,stored in a retrieval system or transmitted in any form or
by any means without the prior permission of the copyrightowners. Permission is not, however, required to copy ab-stracts of papers or of articles on condition that a fullreference to the source is shown. Multiple copying of thecontents of the publication without permission is alwaysillegal.Second class postage paid, at Rahway N. J. Postmaster tosend address changes to: Journal of Clinical Pathology c/oMercury Airfreight International Ltd. Inc., 2323 RandolphAvenue, Avenel, NJ 07001, USA.ISSN 0021-9746.
D TarinDR TurnerDA WmfieldB WoodcockEditor, BMJ
List of assessors
The members of the Editorial Board are indebted to the following for their help with the assessment of papers during the year to September 1995.
B J AddisM C AldridgeR AllakerJ A L AmessM C AndersonT AndersonI D AnsellP P AnthonyN A AthanasouJ BabbB BainS I A BaithunS S BanerjeeJ BellD P BentleyD BerneyP J BerryJ W BradfieldJ BreuerL J R BrownJ BrownC H BuckleyA D BurtE CanningN CaryD CatovskyR CerioH M ChapelT ChardB ChattopadhyayP L ChiodiniD M ClarkB CorrinA CoumbeJ E CrabtreeD CrawfordI A CreeJ CrockerJ CrowM H Cullen0 M CurlingP J DarbyshireS DasJ D DaviesP D DawkinsA DawnayD W DayA R S DeeryU DesselbergerS DillyM F DixonP DomizioL DoyalD DoyleC Du BoulayF P M DunneP DyerC EdwardsI 0 EllisV EmeryA M EmmersonG EvansS J EykynN L K Fagg
I D FarrellP FarthingC FeganC FisherA FleckK A FlemingJ FletcherF V FlynnG M ForbesC S FosterH FoxI M FranklinG L FrenchE GaleP J GallagherK C GatterJ F GeddesR H GeorgeR C GeorgeJ GerdesA T M GhoneimA A M GibsonH M GilmourJ GrangeT A GrayM GreavesD F R GriffithsM H GriffithsK M GrigorR GrunebergW GullickH HambleyP J HamiltonA M HanbyA L HarrisM HarrisI HarrisonC R M HayR J HayD K HenryA HerbertC S HerringtonR E HollimanD HopwoodS HumphreysR IlesJ IronsideP G IsaacsonS M IsmailC IsonA JackV JamesR JarrettI J M JeffreyD J JeffriesS JordanD H M JoynsonI JuhanJ W KeelingJ KeenanC KibblerS E KinseyN KirkhamP KiteG M KonatowiczA S Krajewski
P KyteP L LantosS LeadbeatterR E LeakeF D LeeJ LeeI M LeighD A LevisonJ S LilleymanS N LloydJ S LoweT T MacdonaldS J MachinR N M MacSweenC MakunuraA J MalcolmR R MarplesT MarrsD Y MasonK P McCarthyA C E McCartneyJ McClureJ O'D McGeeP McGooganG McKeeJ E McLaughlinA M McNicolS MedbakA MehtaS MehtarD H MelcherP J MillaP Morgan-CapnerP P MortimerP MossH NielsenA J NortonR T D OliverM G OrmerodR A OwenR J OwenF J ParadinasJ ParkinM C ParkinsonG PasvolR S PereiraL PerryM PignatelliG J PilkingtonA J PinchingT L PittB C PortmanA B PriceJ R QuineyC M QuinnP QuirkeB J RandallD S ReevesM M ReidW A ReidJ T ReillyP A RevellR RiddellG L Ridgway
R A RisdonB E RobertsA J RobertsonS RobinsonW R RocheT RogersP RoseD A RouseG N RuttyG M S ScottN ScottE A SheffieldM SheppardN ShettyM S M ShoushaM P E SlackD N SlaterN G P SlaterJ M SloanR J SokolR C SpencerG StampS G SubbuswamyD M SwirskyM SwornS TabaqchaliD A TabernerI C TalbotG A T TargettD TarinD Taylor-RobinsonJ ThompsonD S TompkinsD R TurnerJ C E UnderwoodA H C UttleyP A van DamP van der ValkP J van DiestP VanezisS VariendD VoakF WalkerR A WalkerB F WarrenR A WhileyW F WhimsterJ A WhittakerH L WhitwellJ WildeD L WilliamsD M WilliamsG T WilliamsP B WilsonA WinderD A WinfieldB E WoodcockA C WotherspoonP A WrightD H WrightJ I WyattA H W WyllieM D Yates
_7 Clin Pathol 1995;48:11 47 1147
I Clin Pathol 1995;48:1148-1151
Volume 48 * Author index
Key: (C) = Correspondence: (E) = Editorial: (L) = Leader
AAbad M, 57Abbas A, 368Abbot NC, 304Abdalla SH, 706Adachi Y, 137, 754Ades AE, 904Agbarakwe AE, 206Aguiar A, 787 (C)Aitola P, 645Al-Jassar AK, 185 (C)Al-Rafaie FN, 110Al Saati T, 826Al-Talib RK, 869Ala FA, 865Alderson D, 129Aleotti A, 553Alguacil-Garcia GF, 579Allen-Mersh TG, 270Allocati N, 1072Alonso MJ, 57Alvisi V, 553Amil Dias J, 787 (C)Anand CM, 214Anderson JR, 597 (L)Anderson SM, 415Andrade L, 53Andrion A, 856Annino L, 955Aqel NM, 185 (C)Arends JW, 408Armstrong C, 596 (C)Armstrong CJ, 689 (C)Asano Y, 115Ashbum D, 64, 689 (C)Athanasou NA, 950Atrah HI, 865Audouin J, 18Aung W, 84Austin EB, 1005Axon ATR, 939Aziza J, 826
BBaak JPA, 620Baatenburg de Jong RJ, 896Baay MFD, 410Babidge WJ, 641Bain B, 1054Bain BJ, 189 (L), 501 (L)Baker A, 1002Balfour AH, 908Ballestin C, 351Banerjee SS, 37, 245Banks RE, 179Barbara L, 1117Bardham KD, 91 (C)Barnett D, 186 (C)Baron DN, 187 (C)Barr JG, 912Barrett SP, 706Barron JL, 463Barry M, 556Bartl R, 477Barton SA, 493Barton SE, 885 (L)Bateman AC, 781Bates CJ, 667Bauer HM, 415Bauters F, 548Baxter KJ, 849Beck JS, 304Beckett GJ, 771Becx MJCM, 250Beer TW, 596 (C)Begg N, 206Bellini C, 519Beltrami CA, 682Benbow EW, 120Bendon RW, 420Bennett JH, 950Bernardi F, 548Bemardi P, 856Bemards AT, 990Betta PG, 856Beuzelin-Yvraut M, 433Bharucha H, 275, 840, 1141Bhatnagar S, 589Biddolph SC, 239Billson V, 1057Birch PJ, 672Birembaut P, 295
Biselli R, 1117Bishop PW, 37Bisset DL, 245, 1059Blondeau JM, 710Boldorini R, 975Bolodeoku J, 463Booker DJ, 602Borg-Grech A, 589Botta M, 856Bouchier Hayes D, 84Bougaran J, 18Bouma G, 346Bourguignat A, 433Bowden SJ, 300Boxman ILA, 896Boyd JF, 883'(C)Brain AN, 1087Breathnach A, 670Bretagne JF, 749Brett M, 785 (C)Bridger JE, 59BrittonJA, 1051Bromley L, 424Broome U, 933Broomhead V, 89Brough WA, 592Brown JS, 300Brown KA, 525Browne RM, 300Buchanan R, 596 (C)Buchanan RC, 387Buchholz RFF, 408Buckley CH, 596 (C)Buist MR, 631Bunce M, 33Bunch C, 260Buntinx F, 408Burger MPM, 410Burke M, 287 (L), 1045BurnieJP, 183, 1130Burns J, 637Burton J, 840Buscher HCJL, 177Butlin SR, 304Buytaert Ph, 147
C
Caballero MD, 223Caballero T, 743Campbell CK, 807Cano D, 571Caracuel MD, 743Carbonell F, 835Carey FA, 616Carey PJ, 545Carneiro F, 787 (C)Carr NJ, 46Carroll SG, 368Carter CJ, 13Cartlidge PHT, 998Caselli M, 553Catovsky D, 189 (L), 835Caul EO, 779Caulet S, 749Cellini L, 1072Chadwick PR, 1068Chambers HM, 420Chan CM, 924Chan KS, 924Chan LC, 861Chan SY, 1022Chant PM, 807Chapel HM, 206, 260Chaperon J, 749Charles AK, 779Chau KY, 578Chau PY, 924Chen S-C, 7 (L)Cheng AFB, 775Cheong S-K, 796Chetty R, 239, 1035Chi DS, 662Chimera JA, 415Chiodini PL, 725Christeff N, 513Christopoulos C, 871Chu C-M, 470Chua A, 133Chui DHK, 861Chung LP, 1022Cimolai N, 488Cinti C, 330
Clark I, 1130Clarke R, 1141Clarke SC, 92 (L)Clarridge JE, 714Clavel C, 295Clemens MR, 291Clutterbuck DJ, 867Coad NAG, 22Coghill G, 304Cohen BJ, 493Cohen-Knafo E, 826Coke AP, 183Colina F, 351Collins BJ, 308Collins N, 611Comley M, 1035Cook HT, 339Cook MG, 689 (C), 1098Cooper K, 393 (C), 786 (C)Copplestone JA, 482Copson ER, 525Corcoran GD, 725Corcuera MT, 57Cordone I, 955Cormican M, 203Cornish JM, 210Cornwell GG, 984 (L)Cosson A, 548Costagliola D, 513Cotton DWK, 398 (L), 497 (L)Covacci A, 41, 967Cowan C, 278Cowling P, 667Craanen ME, 218Crabtree JE, 41, 939, 967Cracknell SE, 1137Crawford DH, 287 (L)Crawford S, 706Creagh T, 59Cree IA, 304Cristina S, 975Crocker J, 539Crook M, 587Cross SS, 402Crouch CF, 652Crusius JBA, 376Cubitt WD, 904Cunningham R, 575Curran T, 7 (L)Cuthbert RJG, 257
DDainelli B, 1072D'Amelio R. 1117Danielsson A, 933Darbyshire PJ, 1051Darmton SJ, 539, 1064Davey KG, 807Davidson AGF, 488Davidson GA, 717Davies DR, 33Davies JD, 737Davies JM, 308Dawson AJ, 998De Angelis C, 519de Angelis ML, 415de Bruijn HWA, 410de Castro S, 223de Koning RW, 250de Maertelaer V, 318de Paco-Moya M, 579De Pauw BE, 474de Roda Husman A-M, 728De Siati L, 519De Silva CE, 110de Sola C, 743De Vuyst P, 318Deans GT, 592DeCarlo L, 553Defize J, 376Delsol G, 826Denton J, 229Denton K, 785 (C)DeRoux SJ, 965Desakorn V, 174Desselberger U, 168, 198Detre S, 876Deville WLJM, 346Dhillon AP, 1070Dickens A, 803Diebold J, 18Diehl V, 1009
Diss TC, 390, 1045Dixon MF, 939Dixon S, 1144Dogan A, 143Donna A, 856Downer CS, 807Dowsett M, 876Drucker DB, 929Dryburgh FJ, 1126Dufty JMK, 901Duk JM, 410Dukers DF, 438Dumortier P, 318Dunne FP, 300Dupond L, 548Durdey P, 272Durlach A, 295Durlach V, 295Duvall E, 616Dworkin MJ, 270Dye R, 616
EEarlam S, 270Echezarreta G, 1035Edwards C, 626Egglestone SI, 101Eichstaedt A, 291Eidt S, 1009El-Agnaf M, 275Elder E, 787 (C)Ellis IO, 981 (L)Elston CW, 981 (L)Erber WN, 308Erickson GA, 466Essed GGM, 408Evans CD, 22Evans DG, 714Evans DJ, 832Evans EGV, 210Evans J, 670Evans MF, 424Evans T, 91 (L)Eykyn SJ, 568
FFabbri M, 330Facchini A, 330Facon T, 548Fagan DG, 763Fahie-Wilson MN, 961Fan X-G, 133Fan X-J, 133Faraggiana T, 955Farina J, 351Farmery SM, 41Farrow M, 545Fasano L, 330Fateh-Moghadam A, 477Fatkenheuer G, 1009Faux JA, 260Fegan C, 105Ferec C, 531Ferguson DA, 662Ferrant A, 679Ferrari A, 955Ferri C, 519Ferry DR, 1064Filby C, 13Finato N, 682Firth JA, 402Fish DE, 59Flavell W, 1070Floretti G, 682Flynn J, 203FogginJJ, 1144Fonk JCM, 346Fonseca K, 214Foot ABM, 210Forbes GM, 308Fordy C, 270Fox H, 678Franqois M, 548Frankton A, 575Franzen C, 1009Fraser A, 908Freemont AJ, 229Frost RWP, 777Fukatsu A, 1093Fukuzawa Y, 1093
1148
Author index
GGaffney EF, 1017Gala JL, 679Galende J, 456Gilenzoski D, 710Gallagher HJ, 84Gallagher PJ, 781, 936Galloway MJ, 1144Galloway PJ, 372, 1126Garcia del Moral R, 743Garcia MA, 456Garcia-Talavera J, 835Gardner F, 584Gasbarrini G, 330Gates A, 257Gatter K, 1035Gatter KC, 239, 447Gaulard P, 18Gazet J-C, 164Gee JMW, 890 (L)Geraghty R, 168, 198Gevenois PA, 318Geyskens M, 147Gharakhanian S, 513Gibb AP, 717 -
Gibson BES, 1051Gilhus NE, 447Gillespie SH, 803Giroux M-A, 531Giubilei E, 955Gledhill A, 939Glennon M, 203Going JJ, 1028Goldin R, 880Goldsmith C, 912Gomez F, 57G6mez-Sanz R, 351Gondo T, 82Gonzalez M, 456Gonzalez-Pina B, 579Gonzalez-Villaron L, 223Goorney B, 658Gorguet B, 826GosneyJR, 1102Gosney MA, 1102Gosselin M, 749G6tz JM, 990Gouerou H, 531Gough D, 865Gough KR, 919Gould SJ, 420Gouldesbrough DR, 181Graham DY, 714Granger V, 186 (C)Gray E, 616Gray JJ, 168, 198, 908Green MA, 1098Greenberg J, 466Greenwald SE, 535Griesmacher A, 1039Griffiths H, 206, 260Grigolo B, 330Grimm M, 1039Groenier KH, 410Gii L, 160Guizzetti S, 975
HHi T, 662Haboubi NY, 226Hachem CY, 714Hagerstrand I, 933Hale RJ, 592Hall J, 545Hallal-Hachem H, 579Hann IM, 1051Hanninen ML, 92 (L)Harach HR, 185 (C)Hardwick RH, 129Hargreaves RM, 260Harmden P, 693 (L)Harris A, 575Harris G, 564Harris M, 37, 245Hashimura M, 1106Hashmi P, 383Hayashi I, 364Hayashi Y, 820Haye KR, 658Heath PK, 771Heatley M, 26, 323, 1031Hellemans P, 147Helmerhorst TJM, 728Hemrika DJ, 815Henry L, 690 (C)Herbrink P, 410Heresbach D, 749Herrington CS, 1 (L), 415Herrmann RP, 308Hiasa Y, 364Higgins G, 168, 198Hill SL, 719Hinchliffe RF, 594, 1137HinnieJ, 1126Ho BSW, 101
Ho C, 383Ho CM, 1022Ho PL, 924Ho-Yen DO, 64, 91 (L), 689 (C)Hoffbrand AV, 110Holt JM, 260Hoogkamp-Korstanje JAA, 474Hopman WPM, 250Hopwood V, 210Horny H-P, 291Horrevorts AM, 474Horstman A, 438Horton VA, 33Hoshii Y, 82Hourihane D, 61Hourihane DO'B, 335How T, 637Howe RA, 667Howie AF, 771Hoyland JA, 229Hrabok D, 710Hruban RH, 218Hubbard R, 1098Hunt CR, 120
Iaru T, 548Ibrahim KMA, 387Iglesias-Osma C, 223Ikeda Y, 137, 754Imbing F, 584Ip M, 775Iqbal A, 257Irving W, 575Isaacson M, 710Isaacson PG, 390, 395 (L), 873,
1045Ishihara T, 82Islam A, 686Itoh H, 820Itoh Y, 115Iwata T, 82Izydorczyk V, 548
JJackson P, 939Jackson PA, 1098Jackson PJ, 689 (C)Jackson SK, 105Jarnerot G, 933Jebakumar SPR, 658Jeffers M, 278Jenner K, 1064Jensen V, 429Jephcott AE, 919Jiwa NM, 438Johnson CP, 637Johnson EM, 210Johnson KH, 984 (L)Johnson PRE, 1005Johnston JI, 372Jones AW, 979 (C)Jones J, 493Jones M, 447Jones TJ, 22Joss AWL, 64, 91 (L), 689 (C)Joyce Wi, 84Juca NT, 351
KKaan JA, 810Kaiserling E, 291Kakumu S, 1093Kamakura T, 137, 754Kamiya M, 1093Kanavaros P, 18Karttunen R, 1111Karttunen T, 1111Kasahara T, 115Kashiwagi T, 82Kasuga M, 820Katoh K, 1093Kawai T, 115Kawashima H, 1093Kay H, 1075 (E)Kazem Y, 648Keeling PWN, 133Kelly C, 616Kenemans P, 631Kennedy GT, 912Kennedy SM, 946Kerbaol M, 749Kerola T, 1111Khan G, 845Khong TY, 420, 494Kinoshita M, 820Kitahori Y, 364Klepetko W, 1039Knottnerus JA, 408Knowles S, 420Knox WF, 120KoYC, 115Kobayashi S, 1093Koerner RJ, 1067Kokkini G, 871
Kolk AHJ, 810Kondratowicz GM, 1074 (C)Konishi N, 364Kopelman PG, 86Kuipers EJ, 376Kumar D, 584Kumar S, 584Kumar U, 880Kupek E, 59Kurban F, 990Kusano E, 115
LLaCorte R, 553Ladekarl M, 429Lagesson V, 979 (C)Lakhani SR, 164, 611Lam KY, 963Lamb D, 616Lambert JR, 969Lambkin HA, 883 (C)Lamers CBHW, 990Lamerz R, 477Lan J, 815Lauwers GY, 965Laws IM, 1070Lawton K, 385Le Berre N, 749Lea JR, 260Leader M, 84Lee AHS, 380Lee ASG, 424Lee D, 1005Lee L, 710Lee M, 260Leigh IM, 1087Leonard MB, 385Leone 0, 267Leung SY, 1022Levi M, 186 (C)Levine T, 496 (C)Lewin JF, 1070Lewis DA, 86Lewis WHP, 101Li C, 662Liang LN, 390Liaw Y-F, 470Lilleyman J, 1075 (E)LilleymanJS, 594, 1051, 1137Limb DI, 1122Lin HY, 75Lin SK, 969Lin YH, 75Linch D, 1045Lindley IJD, 41, 967Link H, 710Lo Y-MD, 33Lock C, 759Lombardi T, 759Loof L, 933Lopez-Berges MC, 456Lopez-Bravo A, 57Lopez-Macedo A, 456Loudon KW, 183Love SB, 849Lowe D, 1075 (E)Lowik CWGM, 896Ludlam CA, 867Lumbreras C, 351Luna A, 124Lunan CB, 278Lusher M, 658Luthra UK, 185 (C)Lye M, 1102Lynch DAF, 939
MMa DFF, 679McAdam KPWJ, 803McAlpine L, 490McBride H, 840McCarthy CJ, 61, 994McClean E, 768McClelland RA, 890 (L)McCluggage WG, 275, 840, 1141McDermott M, 61MacFarlane I, 385McGee JO'D, 415, 424Macgillivray F, 402MacGowan AP, 1067McGregor IL, 737Macheta MP, 181McIlroy J, 1126McIntyre M, 92 (L)McIntyre P, 168, 198McKee TA, 168, 198Mackey H, 768McMahon RFT, 120, 592McMullin MF, 787 (C)McWilliam U, 120Maehara Y, 137Magnani C, 856Mahrle G, 1009Maier U, 314Mainou-Fowler T, 482
Makunura CN, 737Malone M, 535Mandelli F, 955Mann JR, 22Marchini C, 682Mariuzzi L, 682Markey GM, 768Marks CG, 1098Marrano D, 267Martin-Bates E, 59Martin KM, 717Martin N, 18Martinez A, 124Martinez-Albadalejo M, 579Martinez JC, 151Martinez-Salmer6n FJ, 743Masi S, 955Mason CH, 869Mason DY, 18, 796Mateo MS, 151Mathers NJ, 398 (L), 497 (L)Matikainen M, 645Matsuda H, 364Matsumoto K, 364Matsushima K, 115Matthews HR, 539, 1064Mattila A, 645Matutes E, 194 (L), 835Maxwell P, 26, 840, 1031Mead GP, 1138Medina MT, 743Megran DW, 214Meher-Homji N, 368Mehtar S, 1082 (L)Meid JFGM, 474Meijer CJLM, 438, 631, 728, 815Meijer GA, 620Melcher D, 1002Meliconi R, 330Menegatti L, 1117Meroni L, 975Merridew SR, 509Metges J-P, 531Meuwissen SGM, 346, 376Michigishi T, 582Micklem K, 796Middledorp JM, 438Middleton PG, 672Midolo PD, 969Miettinen A, 645Mifsud AJ, 560Miglioli M, 1117Miguel-Garcia A, 835Miguel-Sosa A, 835Millard SH, 641Millis RR, 380Mills MJ, 961Mimori K, 754Minni F, 267Mire-Sluis AR, 525Mizukami Y, 582Moesner J, 878Mojiminiyi OA, 463Molina A, 571Molina Font JA, 571Mollo F, 856Molthoff CFM, 631Monaghan P, 164Monga G, 975Monihan JM, 46Monjardino J, 880Moody AH, 725Mooney EE, 242, 335Moore C, 971Moore CA, 763Moorghen M, 129Morena-Requena J, 579Moreno E, 351Morgan JI, 7 (L)Morgan L, 672Morgan MS, 915Morgan S, 383Mori M, 137, 754Morphopoulos G, 1059Morris AG, 539Morris JA, 929Morris TCM, 768Morrison AE, 867Mortimer PP, 490Morton D, 91 (C)Morton J, 424Mothersill C, 883 (C)Mourits-Andersen T, 878Mowbray MAS, 556Mravunac M, 250Muir KR, 22Mukaida N, 115Mulder AH, 177Mulder S, 810Muller A, 1009Muller MM, 1039Mufioz A, 571Mufioz E, 57Murakata LA, 46Murdoch DA, 1067
1149
Author index
Murphy MJ, 1126Murphy PG, 596 (C)Murphy WG, 717Musich PR, 662Muto S, 115Myers SR, 1087
NNaase MA, 845Nagvekar N, 447Nakamura S, 582Nash JQ, 493Navratil E, 18Navsaria HA, 1087Nduka N, 648Neeson PJ, 387Nelson J, 658Neuhold N, 314Nevado M, 351New NE, 37Newcom SR, 160Newcomb PV, 129Newell A, 885 (L)Newsom-Davis J, 447Ng IOL, 963NgWF, 1061Ng WK, 963, 1061Ni Riain Y, 203Nicholson RI, 890 (L)Nicolaides KH, 368Niemela S, 1111Nijevitch AA, 187 (C)Ninomiya T, 820Nisini R, 1117Niu J, 880Noel H, 679Noell H, 415Noguchi M, 582Nogueras F, 743Nonomura A, 582Noordhoek GT, 810Norton AJ, 883 (C)Norton R, 971Nousbaum J-B, 531Nunez EA, 513Nzeako UC, 46
0Oakhill A, 779, 1051Oakley KL, 1028Oates J, 626Odell EW, 759Offerhaus GJA, 218O'Hare MJ, 164Ohta K, 820Okayasu I, 1106O'Leary G, 946O'Leary JJ, 239Olsson R, 933O'Morain C, 61, 994O'Neill A, 242O'Neill AJ, 1017Ooi K, 1057Oppenheim BA, 1068Orazi A, 884 (C)Orchard G, 1011Orfao A, 151, 456Orradre JL, 151Osinaga E, 433Ostor AG, 1057Osuna E, 124Oudejans JJ, 438Oudkerk Pool M, 346
pPage LA, 525Pals G, 376Pan LX, 390, 1045Papadaki Th, 871Papapoulos SE, 896Parapia LA, 181Parker SP, 904Parkes SE, 22Parkinson MC, 693 (L)Parry JV, 490, 865Patel NR, 662Paz JI, 57Pearson TC, 525Peckham C, 904Pefia AS, 346, 376, 990Pennington TH, 64, 689 (C)Perez-Carceles MD, 124Perrone A, 519Perry S, 41Persaud CA, 568_Pescarmona E, 955Peters M, 98 (L)Pether JVS, 777Phelan L, 1054Phillips E, 433Phillips M, 466Phillips MJ, 186 (C)Pi DW, 13Pignoloni P, 955
Pinder SE, 981 (L)Pinkerton PH, 283 (L)Piris MA, 151Pitt MA, 226, 1059Pitt TL, 174Polak MM, 218Pollock L, 535Pollock LM, 86Ponder BAJ, 789 (L)Porter Hi, 779Porter WH, 179Pouli A, 1098Prentice AG, 482Prescott RJ, 245Prince HM, 387Properzi G, 519Prytz H, 933Puddle B, 950Puglisi F, 682Pulsatelli L, 330Purkis PE, 1087Pye A, 719
QQuirino T, 975
RRaboud JM, 13Radley AS, 545Raha-Chowdhury R, 763Rahimi S, 955Raju GC, 236Ralfkiaer E, 826Ramani P, 390Ramee MP, 749Rampling D, 535Ramsoekh TB, 218Randell J, 86Rappuoli R, 41, 967Rashid A-MH, 678Ratcliffe WA, 300Rattenbury JM, 771Rayner A, 564Raynes JG, 803Reade R, 548Rees A, 556Reeves DS, 1067Rege V, 463Rehman MTA, 229Reid C, 260Reilly JT, 186 (C)Reina J, 683Reynolds GM, 1138Rijs AJMM, 474Riley C, 1057Riley UBG, 706Risse EKJ, 728, 815Robaszkiewicz M, 531Rockett JC, 539Roddy S, 840Rodhain J, 679Rodrigo M, 743Rodrigues FC, 787 (C)Roediger WEW, 641Rogers M, 1054Roldan M, 57Ros MJ, 683Rose DSC, 676Roseto A, 433Rosin D, 880Roth CE, 168, 198Roue-Quintin I, 531Rowlands DC, 1138Rozenbaum W, 513Rubin A, 785 (C)Rubio CA, 1142Ruina M, 553Ruis Peris JM, 242Ruiz C, 571Russell EG, 969Russell NH, 257Russell Jones R, 1011Ryden B-O, 933
SSabas M, 466Saccani Jotti G, 876Saegusa M, 1106Saleh B, 648Salerno A, 689 (C)Salto-Tellez M, 616Salzberger B, 1009Samson J, 759Samson PD, 304San Miguel JF, 223, 456Sanchez-Beato M, 151Santini D, 267Santos M, 787 (C)Santucci A, 519Saul CA, 398 (L), 497 (L)Saunders PWG, 672Savige J, 785 (C)Sayers NM, 929
Scelsi M, 856Schambeck CM, 477Schipper MEI, 815Schlicker HUH, 291Schmitt FC, 53Schrappe M, 1009Schroijen V, 990Schweitzer DH, 896Scott FR, 1070Scott GV, 965Scraggs M, 637Selby PJ, 179Selves J, 826Serra A, 683Shafi MS, 560Shafighian B, 556Shanson D, 490Shaw RJ, 339Sheffield EA, 272Sheikh ZA, 185 (C)Shen-Schwarz S, 420Shepherd NA, 129, 849ShigaJ, 1106Shousha S, 950Shwe KH, 1005Siboni A, 878Side L, 961Sillis M, 493Simak R, 314Simson IW, 733Slater D, 690 (C)Slater DN, 95 (L), 405Slavik T, 733Slavin G, 1075 (E)Sloane JP, 164, 611Smellie WSA, 372, 1126Smith Di, 168, 198Smith JE, 908Smith JP, 466Smith MD, 174, 803Smith PH, 179Smith R, 1002Smith SR, 672Smolka A, 832Snijders PJF, 728So JCC, 861Sobala GM, 939Sobin LH, 46Sokol RJ, 602Soppi E, 645Sousa TR, 787 (C)Speirs GE, 1067Spencer J, 143, 395 (L), 873Spencer RC, 667Spickett GP, 89Stamps R, 602Staples A, 420Start RD, 398 (L), 402, 443, 497
(L)Staunton HA, 70Staunton MJ, 1017Stel HV, 728Stephenson JR, 383Stephenson PM, 936Stevens RF, 1051Stewart JH, 998Stewart M, 37Steyn RS, 1064Stickland JE, 424Stockley RA, 719Stolz E, 410Storey C, 658Stratton MR, 611Su SJ, 75Subedi AMC, 304Sugano M, 820Sugimachi K, 137, 754Suputtamongkol Y, 174Sutehall G, 168, 198Suvama SK, 443Swaminathan R, 587Sweeney E, 994Sweeney EC, 242
TTaberner DA, 901Tagaya T, 1093Tagesson C, 979 (C)Tait RC, 1005Takahashi K, 1093Takahashi M, 82Takano Y, 1106Takazakura E, 582Takiya S, 1093Tarin F, 835Taylor CJ, 771Taylor GM, 339Taylor MB, 904Teerawattanasook N, 174Teh M, 236Teixeira AV, 787 (C)Telfer TP, 380Telford DR, 929Temperton PF, 186 (C)
Teo JGC, 775ter Schegget J, 410Terracini B, 856Theaker JM, 869Thobie N, 513Thomas E, 662Thomas HC, 880Thomas JA, 287 (L)Thomas K, 690 (C)Thomas SM, 556Thurlow PJ, 387Tilanus HW, 177Toghill PJ, 257Tomlinson IPM, 424Tompkins DS, 41, 967Toner P, 26, 1031Toner PG, 275Tosswill J, 865Tovey DG, 725Trendell-Smith NJ, 272Trent R, 689 (C)Trevisani L, 553Trombley C, 488Troncone G, 415Trotta F, 553Turley H, 447Turner A, 919Turner RC, 33Tytgat GNJ, 250
UUberos J, 571Uguccioini M, 330Underwood JCE, 398 (L), 497
(L)
VVaira D, 1117Valenzuela A, 571Vallance DT, 70van Dam PA, 147van de Merwe JP, 346van den Berg FM, 218van den Brule AJC, 815Van der Putten HWHM, 408van der Stoop P, 376van der Valk P, 438van Es JM, 218Van Eyck SL, 415van Krieken JHJM, 896van Lanschot JJB, 177Van Marck E, 147van Oosterom AT, 147van Rensburg EJ, 789 (L)van Zyl H, 733Vazquez L, 223Veenendaal RA, 990Verschoor JSC, 250Verweij PE, 474Veselic M, 990Vidriales MB, 456Vieira DN, 124Ville Y, 368Vincenti AC, 781Vlavianos P, 871Vogl M, 1039Volant A, 531von Blomberg BME, 346Voorhorst Fl, 728Vos W, 438Vujanic GM, 998
WWaghom DJ, 358Wahl SJ, 965Walboomers J, 410Walboomers JMM, 438, 728, 815Walker B, 717Walker J, 335Walker MM, 832Waller JM, 832Wallerstedt S, 933Walsh AL, 174Walshaw L, 710Wang J, 873Wang ZD, 143Wangoo A, 339Warnock DW, 210, 807Warren BF, 272Warter A, 393 (C)Watanabe K, 973Watson ID, 385Watt B, 564, 701 (L)Watts M, 1045Wee A, 236Wehrmann M, 291Weissglas MG, 896Weller RO, 1078 (L)Wells CA, 737Wells S, 245, 1059Westermark P, 984 (L)Westwood NB, 525Wheat PF, 1122Whelan P, 179
1150
Author index
Whetstone R, 168, 198White NJ, 174Whiteside C, 26, 840, 1031Whittaker JA, 105Whyte KF, 91 (L)Wick M, 477Wilcox AH, 463Wilke H, 810Wilkin HJ, 787 (C)Wilkins MJ, 59Willcox N, 447Williams EJ, 509Wilson DV, 509Wilson P, 86Wilson TS, 689 (C)
Wilson Jones E, 1011Wmder AF, 70Wmehouse J, 164Wmstanley TG, 1122Wmter C, 513Wirbel E, 513Witteman EM, 250Wolfaardt M, 733Wong KC, 101Wong LTK, 488Wong MP, 578, 1022Wonke B, 110Worwood M, 763Woyke S, 185 (C)Wreghitt TG, 168, 198, 908
Wu HH, 75Wuthiekanun V, 174Wynne Jones J, 777
x
Xiang Z, 41, 967
yYagihashi N, 973Yagihashi S, 973Yam WC, 924Yamagishi Y, 115Yaschuk Y, 710Yelitcheva ZM, 187 (C)
Yeomans P, 737Yemault J-C, 318Yoon S, 820Young N, 667Yuen KY, 924Yuen ST, 578, 1022Yuoh G, 584
zZaitoun AM, 323Zandecki M, 548Zanelli M, 267Zanen J, 318Zelger B, 1011Zhang YW, 908
1151
Volume 48 * Subject index
AAcute leukaemia, QBEND10 for the diagnosis of
myelodysplastic syndromes in routinely processed bone marrowbiopsy specimens, 291: correspondence, 884
Acute myeloblastic leukaenia, Light scatter characteristicsof blast cells in acute myeloid leukaemia: association withmorphology and immunophenotype, 456
Adenocarcinomac-erbB-2 overexpression in the dysplasia/carcinoma sequence of
Barrett's oesophagus, 129Clear cell adenocarcinoma of the colon, 1142Dieulafoy's disease associated with early gastric cancer, 267Gastric polyposis caused by multiple carcinoids and early
carcinoma, 589OV 632 and MOC 31 in the diagnosis of mesothelioma and
adenocarcinoma: an assessment of their use in formalin fixedand paraffin wax embedded material, 626
Adenoma, Relation between stage, grade, proliferation, andexpression of p53 and CD44 in adenomas and carcinomas ofcolorectum, 1098
Adenomyomatosis, Papillary mucinous adenoma arising inadenomyomatous hyperplasia of the gall bladder, 965
Adenomyomatous hyperplasia, Papillary mucinous adenomaarising in adenomyomatous hyperplasia of the gall bladder, 965
Adenovirus, Fatal adenovirus 32 infection in a bone marrowtransplant recipient, 779
Adhesion molecules, Soluble forms of the adhesion moleculeE-cadherin in urine, 179
Adipose tissue, Immunohistochemical identification of tumoursof adipocytic differentiation using an antibody to aP2 protein,950
Aeromonas sp, Taxonomical and epidemiological investigationsof Aeromonas sp: correspondence, 92
Agar based media, Comparison of agar based media for primaryisolation of Helicobacter pylori, 714
Age, The age related amyloids: a growing family of uniquebiochemical substances, 984
Aggressive angiomyxoma, Angiomyxoid tumour in the renalperipelvic tissues with features of aggressive angiomyxoma, 82
AIDSAcute hepatic and renal failure caused by Pneumocystis carinii
in patients with AIDS, 975Lesser known mycobacteria: leader, 701
Algorithm, Microbiological investigation of polyarthralgia, 777Allograft, Epidermal differentiation and dermal changes in
healing following treatment of surgical wounds with sheets ofcultured allogeneic keratinocytes, 1087
Alpha-fetoprotein, Elevated serum alpha-fetoprotein in a patientwith undifferentiated carcinoma of the gall bladder, 1061
Amniocentesis, Concentration offetal plasma and amniotic fluidinterleukin-1 in pregnancies complicated by preterm prelabouramniorrhexis, 368
Amplityping, IS6110 based amplityping assay and RFLPfingerprinting of clinical isolates of Mycobacterium tuberculosis,924
Amyloid tumour, Amyloid tumour of the colon, 592Amyloids, The age related amyloids: a growing family of unique
biochemical substances, 984Androgens, Differences in androgens of HIV positive patients
with and without Kaposi sarcoma, 513Angiodysplasia, An unusual case of colonic angiodysplasia, 272Angiomyxoma, Angiomyxoid tumour in the renal peripelvic
tissues with features of aggressive angiomyxoma, 82Anogenital cancers, p53 in human papillomavirus associated
anogenital cancers: correspondence, 393Antibody(ies)
Antibodies to human papillomavirus type 16 E7 related toclinicopathological data in patients with cervical carcinoma,410
Leukaemia immunophenotyping: effect of antibody source andfluorochrome on antigen detection: correspondence, 186
Spectrotypic analysis of antibodies to Helicobacter pylori inpatients with antral gastritis and duodenal ulcer, 1117
Use of dried blood spots for the detection and confirmation ofHTLV-1 specific antibodies for epidemiological purposes, 904
AnticoagulantsEvaluation of anticoagulant control in a pharmacist operated
anticoagulant clinic, 545Introduction ofcomputer assisted control oforal anticoagulation
in general practice, 1144Anticomplementary activity, Anticomplementary activity inserum samples from patients with acute parvovirus B 19infection, 493
AntigenDetection of Chlamydia trachomatis antigen by enzymeimmunoassay: importance of confirmatory testing, 214
Latex agglutination for rapid detection of Pseudomonaspseudomallei antigen in urine of patients with melioidosis, 174
Antigen expression, Distribution of OV-TL 3 and MOv18 innormal and malignant ovarian tissue, 631
Antigen test, Use of the Pastorex aspergillus antigen latexagglutination test for the diagnosis of invasive aspergillosis, 210
Antigenaemia, Antigenaemia during acute graft versus hostdisease, 105
Antigliadin antibodies, Antigliadin antibody measurement bychemiluminescence ELISA in the diagnosis of coeliac disease,509
Antimicrobial susceptibility, Quality assessment of MicrobeBase antimicrobial susceptibility data, 1122
Antineutrophil cytoplasmic antibodiesEffect of proctocolectomy on serum antineutrophil cytoplasmic
antibodies in patients with chronic ulcerative colitis, 645Formalin fixation and pattems of antineutrophil cytoplasmic
antibodies, 89Antiserum, Detection of Ki67 antigen by a new sheep polyclonal
antiserum, 1138Antral gastritis, Spectrotypic analysis ofantibodies to Helicobacter
pylon in patients with antral gastritis and duodenal ulcer, 1117Antral mucosa, Early ultrastructural changes of antral mucosa
with aspirin in the absence of Helicobacter pyloni, 994ap2 protein, Immunohistochemical identification of tumours of
adipocytic differentiation using an antibody to aP2 protein, 950API 20C, Evaluation ofthe AUXACOLOR system, a new method
of clinical yeast identification, 807API-Campy System, Evaluation of the API-Campy System in
the biochemical identification of hippurate negativecampylobacter strains isolated from faeces, 683
Apocrine metaplasia, Apocrine adenosis: a precursor ofaggressive breast cancer?, 737
Apolipoprotein E, Rapid and safe determination of humanapolipoprotein E genotypes by miniaturised SDS-PAGE in non-insulin dependent diabetes mellitus, 295
Apolipoproteins, Limited discriminant value of lipoprotein AI,lipoprotein Lp(a) and other lipoprotein particles in patients withand without early onset ischaemic heart disease, 70
ApoptosisApoptosis in the nervous system: new revelations: leader, 7Apoptotic and mitotic indices in malignant melanoma and basal
cell carcinoma, 242Effect of interleukins on the proliferation and survival of B cell
chronic lymphocytic leukaemia cells, 482In situ end-labelling, light microscopic assessment and
ultrastructure of apoptosis in lung carcinoma, 1017Role oftransforming growth factor betal on hepatic regenerationand apoptosis in liver diseases, 1093
Appendix, Combined goblet cell carcinoid and mucinouscystadenoma of the appendix, 869
Arthritis, Acute gonococcal arthritis: an unusual host andpathogen combination, 86
Arthropathy, Anticomplementary activity in serum samples frompatients with acute parvovirus B19 infection, 493
Arthroscopy, Histological changes associated with an artificialanterior cruciate ligament, 556
Artificial RFLP PCR, HLA typing for DR3 and DR4 usingartifical restriction fragment length polymorphism PCR fromarchival DNA, 33
1152 I Clin Pathol 1995;48:1152-1166
Subject index
Aspergillosis, Clinical evaluation and reproducibility of thePastorex Aspergillus antigen latex agglutination test fordiagnosing invasive aspergillosis, 474
Aspergillus"Pseudoclusters" and typing by random amplification ofpolymorphic DNA of Aspergillusfumigatus, 183
Use of the Pastorex aspergillus antigen latex agglutination testfor the diagnosis of invasive aspergillosis, 210
Aspirin, Early ultrastructural changes of antral mucosa withaspirin in the absence of Helicobacter pylon, 994
Atypical ductal hyperplasia, Atypical ductal hyperplasia ofthe breast: clonal proliferation with loss of heterozygosity onchromosomes 16q and 17p, 611
AuditAudit of an emergency biochemistry service, 1126Audit oftumour histopathology reviewed by a regional oncology
centre, 245Audit of tumour pathology reviewed by a regional oncology
centre: correspondence, 690Blood bank audit: leader, 283Can histopathologists diagnose bronchopneumonia?, 120Internal audit in a microbiology laboratory, 560Laboratory turnround time: closing the loop, 372Multifactorial audit of invasive cervical cancer: key lessons for
the National Screening Programme, 405: correspondence, 785Perinatal and infant postmortem examinations: how well are we
doing?, 998Prospective audit of mucosal biopsy specimens of the
gastrointestinal tract, 936Review ofa consultant microbiologist's work practice - an audit:
leader, 1082Autoantibodies, Detection of autoantibodies to neutrophil
cytoplasmic antigens: correspondence, 785Autoimmune haemolytic anaemia, Investigation of patients
with autoimmune haemolytic anaemia and provision of bloodfor transfusion, 602
Automated blood count, Screening criterial for thalassaemiatrait in pregnant women, 1054
Autopsy, Public perceptions of necropsy: leader, 497AUXACOLOR, Evaluation of the AUXACOLOR system, a newmethod of clinical yeast identification, 807
Avidity, Avidity ofspecific IgG antibodies elicited by immunisationagainsts Haemophilus influenzae type b, 206
BB cell leukaemia, Effect of interleukins on the proliferation and
survival of B cell chronic lymphocytic leukaemia cells, 482B cell lymphoma
Clinicopathologic implications of Epstein-Barr virus related Bcell lymphoma in immunocompromised patients: leader, 287
Immunohistochemical analysis ofT cell proliferation in normaltonsil and B cell lymphoma, 873
B cell phenotype, Immunophenotypic analysis of childhoodBurkitt's lymphoma in the West Midlands 1957-1986, 22
BacT/AlertDetection ofbacteraemia by the continuously monitoring BacT/
Alert system, 912Growth and detection of filamentous fungi in the BacT/Alertblood culture system, 670
BacteraemiaBacteraemia caused by Campylobacter spp: correspondence, 596Detection ofbacteraemia by the continuously monitoring BacT/
Alert system, 912Bacteria, Simple method for quantifying viable bacterial numbers
in sputum, 719Barrett's oesophagus, c-erbB-2 overexpression in the dysplasia/
carcinoma sequence of Barrett's oesophagus, 129Basal cell carcinoma, Apoptotic and mitotic indices in malignantmelanoma and basal cell carcinoma, 242
bcl-2 protein expressionExpression of the bcl-2 protein in B cell lymphomas arisingfrom mucosa associated lymphoid tissue, 18
Immunohistochemical detection of p53 and Bcl-2 proteins inHashimoto's thyroiditis and primary thyroid lymphomas, 239
p53, Rb and bcl-2 expression during the cell cycle: a study inphytohaemagglutinin stimulated lymphocytes and microwaveirradiated lymphoid tissue sections, 151
Biochemical variables, Variation in serum electrolytes andenzyme concentrations in patients with sickle cell disease, 648
BiopsyDistribution of cervical intraepithelial neoplasia: are
hysterectomy specimens sampled appropriately?, 323
Prospective audit of mucosal biopsy specimens of thegastrointestinal tract, 936
Sampling variability of percutaneous liver biopsy in primarysclerosing cholangitis, 933
Bladder cancerPseudoangiosarcomatous carcinoma of the genitourinary tract,
1059Soluble forms of the adhesion molecule E-cadherin in urine,
179BloodA new, fast and convenient method for layering blood or bonemarrow over density gradient medium, 686
Rate of growth of Pseudomonasfluorescens in donated blood, 717Blood bank, Blood bank audit: leader, 283Blood cultureDo blood cultures need continuous monitoring so that clinical
action can be taken outside normal working hours?, 1067Documentation of blood culture results, 667Growth and detection of filamentous fungi in the BacT/Alertblood culture system, 670
Blood donors, Management of blood donors whose donationsare repeatedly falsely positive by the HIV antibody screeningtest, 865
Blood rheology, Relationship of blood rheology to lipoproteinprofile during normal pregnancies and those with intrauterinegrowth retardation, 571
Blood for transfusion, Investigation ofpatients with autoimmunehaemolytic anaemia and provision of blood for transfusion, 602
Bone marrowA new, fast and convenient method for layering blood or bonemarrow over density gradient medium, 686
Non-neoplastic glandular structures in bone marrow: a technicalartefact, 1141
QBEND1O for the diagnosis of myelodysplastic syndromes inroutinely processed bone marrow biopsy specimens, 291:correspondence, 884
Bone marrow biopsy, Detection ofmycobacteria in bone marrowbiopsy specimens taken to investigate pyrexia ofunknown origin,706
Bone marrow granulomas, Granulomatous bone marrowinflammation during treatment of chronic myeloid leukaemiawith interferon alpha-2b, 878
Bone marrow studies, Recurrent thrombotic occlusions ofarteries and veins caused by intravascular metastaticadenocarcinoma: correspondence, 186
Bone marrow transplantationFatal adenovirus 32 infection in a bone marrow transplant
recipient, 779Functional hyposplenism following allogeneic bone marrow
transplantation, 257Immunohistochemical changes in sigmoid colon after allogeneicand autologous bone marrow transplantation, 308
Bone marrow trephine biopsyB cell signet-ring cell lymphoma of bone marrow, 275Immunohistochemical staining of plastic embedded bonemarrow trephine biopsy specimens after microwave heating,840
Immunohistochemistry in apparently normal bone marrowtrephine specimens from patients with nodal follicularlymphoma, 1035
Book reviewsBeeching NJ, Cheesbrough JS. Infectious diseases. Illustrated
case histories, 281Dail DH, Hammar SP, editors. Pulmonary pathology, 2nd edn,
281Ehrmann RL. Benign to malignant progression in cervicalsquamous epithelium, 691
Epler GR, ediwr. Diseases of the bronchioles, 884Essex M, Mboup S, Kanki PJ, Kalengayi MR, editors. AIDS in
Africa, 281Gompel C, Silverberg SG, editors. Pathology in gynecology and
obstetrics, 4th edn, 94Heller DS. The endometrium. A clinicopathologic approach,
787Joshi VV. Common problems in pediatric pathology, 691Kaplan CG. Color atlas of gross placental pathology, 691Lack EE. Pathology of adrenal and extra-adrenal paraganglia.
Vol 29 in series Major problems in pathology, 281Leevy CM, Sherlock S, Tygstrum N, Zetterman R, editors.
Diseases of the liver and biliary tract: standardization ofnomenclature, diagnostic criteria, and prognosis, 393
1153
Subject index
Marchevsky AM, Bartels PH, editors. Image analysis: a primerfor pathologists, 691
Mason JK, editor. The pathology of trauma, 2nd edn, 93Nonnenmacher TF, Losa GA, Weibel ER, editors. Fractals in
biology and medicine, 93Pneumocystis carinii pneumonia. 2nd edn. Lung biology in healthand disease, 92
Saldana MJ, editor. Pathology of pulmonary disease, 93Scheuer PJ, Lefkowitch JH. Liver biopsy interpretation, 5th
edn. Vol 31 in series Major problems in pathology, 788Sekiguchi S, editor. Clinical application of leukocyte depletion,94
Taylor CR, Cote RJ. Immunomicroscopy: a diagnostic tool forthe surgical pathologist. Vol 19 in series Major problems inpathology, 281
Thatcher N, Spiro S, editors. New perspectives in lung cancer,93
Woodruff JD, Angtuaco TL, Parmley TH. Atlas of gynecologicpathology, 2nd edn, 690
Working party on human tissue chaired by Professor DameRosalinde Hurley. Human tissue: ethical and legal issues,1074
World Health Organisation. IARC Monographs on theevaluation of carcinogenic risks to humans, vol 59, hepatitisviruses, 691
Borderline abnormalities, Pathologist variation in reportingcervical borderline epithelial abnormalities and cervicalintraepithelial neoplasia, 59
Breast cancer (carcinoma)A "quickscore" method for immunohistochemical
semiquantitation: validation for oestrogen receptor in breastcarcinomas, 876
Apocrine adenosis: a precursor of aggressive breast cancer?, 737Atypical ductal hyperplasia of the breast: clonal proliferation
with loss of heterozygosity on chromosomes 16q and 17p,611
Immunohistochemical quantitation of oestrogen receptors andproliferative activity in oestrogen receptor positive breastcancer, 429
Immunohistochemical study of topoisomerase II-alphaexpression in primary ductal carcinoma of the breast, 147
Loss of heterozygosity on chromosome llq in breast cancer,424
Malignant myoepithelioma (myoepithelial carcinoma) of thebreast: a detailed cytokeratin study, 164
Metastatic breast carcinoma with appearance resemblingmicropapillary ductal carcinoma in situ, 380
Prognostic factors in primary breast carcinoma: leader, 981Specimen slice radiography of cancer in breast conserving
excisions, 1028Spectrum of carcinoembryonic antigen immunoreactivity from
isolated ductal hyperplasias to atypical hyperplasias associatedwith infiltrating ductal breast cancer, 53
Breast diseaseCytokeratin intermediate filament expression in benign and
malignant breast disease, 26Paget's disease of the breast: correspondence, 393
Breast-ovarian cancer, Molecular genetics of familial breast-ovarian cancer: leader, 789
Breath isoprene, Origins of breath isoprene: correspondence, 979Breath tests, Volatile organic compounds in the breath ofpatients
with schizophrenia, 466Brenner tumour, Brenner tumour of the vagina, 678Bronchial carcinoma
Orthostatic hypotension and vasodilatory peptides in bronchialcarcinoma, 1102
Osteolytic bone lesions in a patient with idiopathic myelofibrosisand bronchial carcinoma, 867
Bronchopneumonia, Can histopathologists diagnosebronchopneumonia?, 120
Burkholderia cepacia, Selective media for isolation ofBurkholderia (Pseudomonas) cepacia from the respiratorysecretions of patients with cystic fibrosis, 488
Burkitt's lymphoma, Immunophenotypic analysis of childhoodBurkitt's lymphoma in the West Midlands 1957-1986, 22
Cc-erbB-2, c-erbB-2 overexpression in the dysplasia/carcinoma
sequence of Barrett's oesophagus, 129C-polysaccharide, Detection of C-polysaccharide in serum of
patients with Streptococcus pneumoniae bacteraemia, 803
CagAHelicobacter pylori induced interleukin-8 expression in gastric
epithelial cells is associated with CagA positive phenotype,41
Induction of interleukin-8 secretion from gastric epithelial cellsby a cagA negative isogenic mutant of Helicobacter pylon, 967
Calcium binding, Hypercalcaemia due to calcium binding IgMparaprotein in Waldenstrom's macroglobulinaemia, 961
Campylobacter sppBacteraemia caused by Campylobacter spp: correspondence, 596Evaluation of the API-Campy System in the biochemical
identification of hippurate negative campylobacter strainsisolated from faeces, 683
Cancer, Steroid hormone receptors and their clinical significancein cancer: leader, 890
Carcinoembryonic antigen, Spectrum of carcinoembryonicantigen immunoreactivity from isolated ductal hyperplasias toatypical hyperplasias associated with infiltrating ductal breastcancer, 53
Carcinoid, Gastric polyposis caused by multiple carcinoids andearly carcinoma, 589
Carcinoma in situ, Specimen slice radiography of cancer inbreast conserving excisions, 1028
Cardiac myxoma, S100, alpha-smooth muscle actin andcytokeratin 19 immunohistochemistry in odontogenic and softtissue myxomas, 759
CD antigen, Activated phenotype in neutrophils and monocytesfrom patients with primary proliferative polycythaemia, 525
CD3 negative large granular lymphocytes, Longstandingproliferation of CD3 negative large granular lymphocytespreceding the development of high grade non-Hodgkin'slymphoma, 672
CD4, Lymphocyte subset counts in skin puncture and venousblood compared, 1137
CD8, Lymphocyte subset counts in skin puncture and venousblood compared, 1137
CD19, CDl9 and immunophenotype of bone marrow plasmacells in monoclonal gammopathy of undetermined significance,548
CD31, Immunostaining for CD31 and CD34 in Kaposi sarcoma,1011
CD34Immunostaining for CD31 and CD34 in Kaposi sarcoma, 1011QBEND1O for the diagnosis of myelodysplastic syndromes in
routinely processed bone marrow biopsy specimens, 291:correspondence, 884
CD44, Relation between stage, grade, proliferation, and expressionof p53 and CD44 in adenomas and carcinomas of colorectum,1098
Cell death, Apoptosis in the nervous system: new revelations:leader, 7
Cell proliferation, Detection of Ki67 antigen by a new sheeppolyclonal antiserum, 1138
Cellular immediate-early gene response, Apoptosis in thenervous system: new revelations: leader, 7
Central retinal vein thrombosis, Acquired protein S deficiencyin a patient with systemic lupus erythematosus causing centralretinal vein thrombosis, 387
Central venous catheter, Corynebacterium aquaticum septicaemiain a neutropenic patient, 971
Ceroid granuloma, Ceroid granulomas in the female genitalsystem, 1057
Cervical biopsy, Diagnosis of genital infection caused by humanpapillomavirus using in situ hybridisation: the importance ofthe size of the biopsy specimen, 57
Cervical cancerAntibodies to human papillomavirus type 16 E7 related to
clinicopathological data in patients with cervical carcinoma,410
Comparative analysis of human papillomavirus detection byPCR and non-isotopic in situ hybridisation, 415
Human papillomavirus in false negative archival cervical smears:implications for screening for cervical cancer, 728
Cervical cytology, Cervical cytology external and internal qualityassurance: a comparative appraisal: leader, 95
Cervical intraepithelial neoplasiaDistribution of cervical intraepithelial neoplasia: are
hysterectomy specimens sampled appropriately?, 323Pathologist variation in reporting cervical borderline epithelial
abnormalities and cervical intraepithelial neoplasia, 59
1154
Subject index
Cervical neoplasia, Human papillomaviruses and cervicalneoplasia. II. Interaction of HPV with other factors: leader, 1
Cervical screeningComposition of cervical smears in patients with and without a
cervical ectropion, 408Multifactorial audit of invasive cervical cancer: key lessons for
the National Screening Programme, 405: correspondence, 785Role ofre-screening ofcervical smears in internal quality control,
1002Cervix
Ceroid granulomas in the female genital system, 1057Detection of integrated human papillomavirus 16 DNA insquamous cell carcinoma of the cervix: correspondence, 393
Chemiluminescence, Antigliadin antibody measurement bychemiluminescence ELISA in the diagnosis of coeliac disease,509
Chemotherapy, Lack of correlation of P-glycoprotein expressionwith response to MIC chemotherapy in oesophageal cancer,1064
Childhood lymphoblastic leukaemia, Changes incytomorphology of childhood lymphoblastic leukaemia at thetime of disease relapse, 1051
Chinese, Seasonal variation in the necropsy incidence ofpulmonary thromboembolism in Hong Kong, 578
Chlamydia trachomatisChlamydia trachomatis and ectopic pregnancy: retrospective
analysis of salpingectomy specimens, endometrial biopsies,and cervical smears, 815
Detection of Chlamydia trachomatis antigen by enzymeimmunoassay: importance of confirmatory testing, 214
Duplex PCR system for simultaneous detection of Neisseriagonorrhoeae and Chlamydia trachomatis in clinical specimens,101
Value of screening for oro-pharyngeal Chlamydia trachomatisinfection, 658
Chondral damage, Histological changes associated with anartificial anterior cruciate ligament, 556
Chromogranin immunostaining, Chromogranin positive cellsin colorectal carcinoma and transitional mucosa, 754
ChromosomesAtypical ductal hyperplasia of the breast: clonal proliferation
with loss of heterozygosity on chromosomes 16q and 17p,611
Loss of heterozygosity on chromosome llq in breast cancer,424
Chronic lymphocytic leukaemiaEffect of interleukins on the proliferation and survival of B cell
chronic lymphocytic leukaemia cells, 482Renal failure in a patient with chronic lymphocytic leukaemia
treated with fludarabine, 181Cigarette smoking, Free radical activity in young adult cigarette
smokers, 385Cirrhosis, Waterhouse-Friderichsen syndrome complicatingprimary biliary sepsis due to Pasteurella multocida in a patientwith cirrhosis, 775
Clear cells, Clear cell adenocarcinoma of the colon, 1142Clinical virology, Internal quality assurance in a clinical virology
laboratory. I. Internal quality assessment, 168Coagulometer, Effect of thromboplastin and coagulometer
interaction on the precision of the International NormalisedRatio, 13
Coeliac diseaseAntigliadin antibody measurement by chemiluminescenceELISA in the diagnosis of coeliac disease, 509
Lymphocytic gastritis and associated small bowel disease: adiffuse lymphocytic gastroenteropathy?, 939
Pitfalls in diagnosing coeliac disease: correspondence, 787ColonAmyloid tumour of the colon, 592Clear cell adenocarcinoma of the colon, 1142
Colonic angiodysplasia, An unusual case of colonicangiodysplasia, 272
Colonocytes, Thiol methyltransferase activity in colonocytes anderythrocyte membranes, 641
Colorectal adenoma, Quantification of proliferative activity incolorectal adenomas by mitotic counts: relationship to degreeof dysplasia and histological type, 620
Colorectal biopsy specimens, Histological discrimination ofidiopathic inflammatory bowel disease from other types of colitis,749
Colorectal cancer (carcinoma)Amyloid tumour of the colon, 592Chromogranin positive cells in colorectal carcinoma and
transitional mucosa, 754Importance of hepatic artery node involvement in patients with
colorectal liver metastases, 270Relation between stage, grade, proliferation, and expression ofp53 and CD44 in adenomas and carcinomas of colorectum,1098
Commercial media, Enteric media: pre-poured or in-house?,568
Common variable immunodeficiency, Hodgkin's disease in apatient with common variable immunodeficiency, 871
Competitive RT-PCR, Quantitation of hepatitis C viral RNA inliver and serum samples using competitive polymerase chainreaction, 820
Computer assistance, Macroscopic assessment of pulmonaryemphysema by image analysis, 318
Computer assisted guidelines, Managing test demand byclinicians: computer assisted guidelines: leader, 98
Computerised image handling, Computerised image handlingin pathology: leader, 796
Conjunctiva, HPV type 16 in conjunctival and junctionalpapilloma, dysplasia, and squamous cell carcinoma, 1106
Consultant microbiologist, Review of a consultantmicrobiologist's work practice - an audit: leader, 1082
Contamination, Rate of growth of Pseudomonas fluorescens indonated blood, 717
Continuous ambulatory peritoneal dialysis, Specific increasein interleukin-8 concentrations in dialysis fluid of patients withperitonitis receiving continuous ambulatory peritoneal dialysis,115
Continuous monitoringDetection ofbacteraemia by the continuously monitoring BacT/
Alert system, 912Do blood cultures need continuous monitoring so that clinical
action can be taken outside normal working hours?, 1067Core analyses, Laboratory turnround time: closing the loop, 372Coronary artery bypass graft, Limited discriminant value of
lipoprotein AI, lipoprotein Lp(a) and other lipoprotein particlesin patients with and without early onset ischaemic heart disease,70
Coronary artery dissection, Sudden death from coronary arterydissection, 781
Correction, 1074Corynebacterium aquaticum, Corynebacterium aquaticum
septicaemia in a neutropenic patient, 971Crohn's disease
E-cadherin expression in intestinal epithelium, 143Histological discrimination of idiopathic inflammatory bowel
disease from other types of colitis, 749Intraepithelial and lamina propria leucocyte subsets in
inflammatory bowel disease: an immunohistochemical studyof colon and rectal biopsy specimens, 743
Relation of granulomas to lymphatic vessels in Crohn's disease,335
Serological markers to differentiate between ulcerative colitisand Crohn's disease, 346
Cruciate ligament, Histological changes associated with anartificial anterior cruciate ligament, 556
Crystal violet, Contamination of crystal violet in the Gram stainmethod: correspondence, 92
Cult-Dip Plus dip slide, Evaluation of the Cult-Dip Plus dipslide method for urinary tract infection, 710
Culture mediaCommercially available versus home produced egg media for
isolation of mycobacteria, 564Comparison of agar based media for primary isolation of
Helicobacter pylori, 714Culture negative endocarditis, Immunoblotting in the diagnosis
of culture negative endocarditis caused by streptococci andenterococci, 1130
Cyclophosphamide, Idiopathic granulomatous vasculitis:response to immunosuppressive therapy, 579
Cyclosporin A, Tissue polypeptide specific antigen for thedetection of lymphoproliferative diseases induced bycyclosporin, 1039
Cyst antigen, Serological reactivity against cyst and tachyzoiteantigens of Toxoplasma gondii determined by FAST-ELISA, 908
1155
Subject index
Cystic fibrosisSelective media for isolation of Burkholderia (Pseudomonas)
cepacia from the respiratory secretions of patients with cysticfibrosis, 488
Serum glutathione S-transferase B1 activity as an index of liverfunction in cystic fibrosis, 771
Cytodiagnosis, Cytodiagnosis and the necropsy, 443Cytokeratin
Cimentin and cytokeratin expression in nodular hyperplasia andcarcinoma of the prostate, 1031
Cytokeratin intermediate filament expression in benign andmalignant breast disease, 26
Malignant myoepithelioma (myoepithelial carcinoma) of thebreast: a detailed cytokeratin study, 164
Cytokeratin 19, S 100, alpha-smooth muscle actin and cytokeratin19 immunohistochemistry in odontogenic and soft tissuemyxomas, 759
Cytology, The clinical value of urinary cytology: 12 years ofexperience with 615 patients, 314
CytomegalovirusDetection of cytomegalovirus using PCR in serum from renal
transplant recipients, 575Histological diagnosis of cytomegalovirus hepatitis in liver
allografts, 351Cytoskeletal proteins, Cytokeratin intermediate filament
expression in benign and malignant breast disease, 26
D83D4 cancer, Immunocytological analysis of the Tn associated
antigen 83D4 in serous effusions from patients with cancer:comparison with Tn soluble glycoprotein, 433
Data, Quality assessment of Microbe Base antimicrobialsusceptibility data, 1122
Deferiprone, Changes in transferrin saturation after treatmentwith the oral iron chelator deferiprone in patients with ironoverload, 110
Delayed type hypersensitivity, Enhanced expression of type 1procollagen and transforming growth factor-beta in tuberculininduced delayed type hypersensitivity, 339
Density gradient dispenser, A new, fast and convenient methodfor layering blood or bone marrow over density gradientmedium, 686
Desmin, Desmin expression in rhabdomyosarcoma: influence ofthe desmin clone and immunohistochemical method, 535
Diabetes, HLA typing for DR3 and DR4 using artifical restrictionfragment length polymorphism PCR from archival DNA, 33
Dieulafoy's disease, Dieulafoy's disease associated with earlygastric cancer, 267
Dip slide, Evaluation of the Cult-Dip Plus dip slide method forurinary tract infection, 710
Diverticular disease, An unusual case of colonic angiodysplasia,272
DNA cytometry, Interobserver variation in cell selection forDNAimage cytometry, 616
Documentation, Documentation of blood culture results, 667Down syndrome, Transient abnormal myelopoiesis accompaniedby hepatic fibrosis in two infants with Down syndrome, 973
Dried blood spots, Use of dried blood spots for the detection andconfirmation of HTLV-1 specific antibodies for epidemiologicalpurposes, 904
Drug resistance, P-glycoprotein positive, drug resistant invasivelymphoepithelial thymoma: treatment response tochemotherapy with cyclosporin and quinine, 679
Drug therapy, Introduction of computer assisted control of oralanticoagulation in general practice, 1144
Dry latex agglutination test, A practical single sample dry latexagglutination test for Helicobacter pylori antibody detection, 969
Ductal hyperplasia, Spectrum of carcinoembryonic antigenimmunoreactivity from isolated ductal hyperplasias to atypicalhyperplasias associated with infiltrating ductal breast cancer, 53
Duodenal ulcer, Spectrotypic analysis of antibodies toHelicobacter pylori in patients with antral gastritis and duodenalulcer, 1117
Duplex PCR, Duplex PCR system for simultaneous detectionof Neisseria gonorrhoeae and Chlamydia trachomatis in clinicalspecimens, 101
Dyspepsia, Failure to detect Helicobacter pylon in nasal mucus inH. pylori positive dyspeptic patients, 1072
Dysplasialcarcinoma sequence, c-erbB-2 overexpression in thedysplasia/carcinoma sequence of Barrett's oesophagus, 129
EE-cadherin
E-cadherin expression in intestinal epithelium, 143Soluble forms of the adhesion molecule E-cadherin in urine,
179Ectopic pregnancy, Chlamydia trachomatis and ectopic
pregnancy: retrospective analysis of salpingectomy specimens,endometrial biopsies, and cervical smears, 815
Ectopic secretion, Orthostatic hypotension and vasodilatorypeptides in bronchial carcinoma, 1102
Editors, Editors on editors: editorial, 1075Egg media, Commercially available versus home produced eggmedia for isolation of mycobacteria, 564
Electron microscopy, Detection and identification ofgastrointestinal microsporidia using non-invasive techniques,725
Emergency laboratory, Audit of an emergency biochemistryservice, 1126
Endometriosis, Ceroid granulomas in the female genital system,1057
Endometrium, Necrobiotic granulomas of the urogenital system:correspondence, 185
Endothelin, Endothelin-I in idiopathic pulmonary fibrosis, 330Endothelin-1, Circulating endothelin-l concentrations in
patients with chronic hypoxia, 519Endotoxaemia, Antigenaemia during acute graft versus host
disease, 105Enhanced chenmiluinescence, Enzyme immunoassays for IgGand IgM antibodies to Toxoplasma gondii based on enhancedchemiluminescence, 652
Enteric media, Enteric media: pre-poured or in-house?, 568Enterobacteria, Lethal synergy between toxins of staphylococciand enterobacteria: implications for sudden infant deathsyndrome, 929
Enterococcus faecium, Neomycin blood agar as a selectivemedium for vancomycin resistant Enterococcus faecium, 1068
Enzyme immunoassay, Detection of Chlamydia trachomatisantigen by enzyme immunoasasay: importance of confirmatorytesting, 214
Enzyme-linked inmmunosorbent assayAntigliadin antibody measurement by chemiluminescenceELISA in the diagnosis of coeliac disease, 509
Diagnosis of Helicobacter pylon infection by specific gastricmucosal IgA and IgG pylori antibodies, 990
Management of blood donors whose donations are repeatedlyfalsely positive by the HIV antibody screening test, 865
Epidermal growth factor receptor, Oncogene proteins andproliferation antigens in thymomas: increased expression ofepidermal growth factor receptor and Ki67 antigen, 447
Epithelial cells, Induction of interleukin-8 secretion from gastricepithelial cells by a cagA negative isogenic mutant of Helicobacterpylon, 967
Epithelial damage, Improvement of gastric inflammation andresolution of epithelial damage one year after eradication ofHelicobacter pylori, 250
Epstein-Barr virusAssociation of Epstein-Barr virus with sinonasal angiocentric T
cell lymphoma, 946Clinicopathologic implications of Epstein-Barr virus related B
cell lymphoma in immunocompromised patients: leader, 287Down-regulation of Epstein-Barr virus nuclear antigen 1 in
Reed-Steinberg cells of Hodgkin's disease, 845Epstein-Barr virus associated lymphoproliferative disorder with
fatal involvement of the gastrointestinal tract in an infant,390
Immunohistochemical demonstration of different latentmembrane protein-1 epitopes of Epstein-Barr virus inlymphoproliferative diseases, 438
Lymphoepithelial carcinoma of the salivary gland: in situdetection of Epstein-Barr virus, 1022
Erythrocyte membranes, Thiol methyltransferase activity incolonocytes and erythrocyte membranes, 641
Escherichia coli, Evaluation of the Cult-Dip Plus dip slidemethod for urinary tract infection, 710
FFAB typing, Changes in cytomorphology of childhood
lymphoblastic leukaemia at the time of disease relapse, 1051Faecal specinens, Detection and identification of
gastrointestinal microsporidia using non-invasive techniques,725
1156
Subject index
Faeces, Evaluation of the API-Campy System in the biochemicalidentification of hippurate negative campylobacter strainsisolated from faeces, 683
Familial breast-ovarian cancer, Molecular genetics of familialbreast-ovarian cancer: leader, 789
FAST-ELISA, Serological reactivity against cyst and tachyzoiteantigens of Toxoplasma gondii determined by FAST-ELISA, 908
Ferrtin, Postmortem blood ferritin concentrations in suddeninfant death syndrome, 763
Fetomaternal haemorrhage, Flow cytometry in diagnosis andmanagement of large fetomaternal haemorrhage, 1005
Filamentous fungi, Growth and detection of filamentous fungiin the BacT/Alert blood culture system, 670
Fine needle aspiration cytology, Occult papillarymicrocarcinoma of the thyroid: a potential pitfall of fine needleaspiration cytology? Is it possible to avoid it?, correspondence,185
Florid granulomatosis, Gold granuloma after accidentalimplantation, 1070
Flow cytometryFlow cytometry in diagnosis and management of large
fetomaternal haemorrhage, 1005Plasma cell proliferation in monoclonal gammopathies:measurement using BU-1 antibody in flow cytometry andmicroscopy: comparison with serum thymidine kinase, 477
Fludarabine, Renal failure in a patient with chronic lymphocyticleukaemia treated with fludarabine, 181
Fluorescence antibody test, Comparison of three methods forculture confirmation of Neisseria gonorrhoeae strains currentlycirculating in the UK, 919
Fluorochrome, Leukaemia immunophenotyping: effect ofantibody source and fluorochrome on antigen detection:correspondence, 186
Follow up, Ten year follow up study of lymphocytic gastritis:further evidence on Helicobacter pylon as a cause of lymphocyticgastritis and corpus gastritis, 1111
Free radical markers, Free radical activity in young adultcigarette smokers, 385
Fungal infection, Iron metabolism and fungal infections inpatients with haematological malignancies, 223
GGalactomannan, Clinical evaluation and reproducibility of the
Pastorex Aspergillus antigen latex agglutination test fordiagnosing invasive aspergillosis, 474
Gall bladder, Papillary mucinous adenoma arising inadenomyomatous hyperplasia of the gall bladder, 965
Gangliocytic paraganglioma, Gastrointestinal haemorrhagefrom a jejunal gangliocytic paraganglioma, 84
Gastric biopsy, Effect of transport medium and transportationtime on culture of Helicobacter pylon from gastric biopsyspecimens: correspondence, 91
Gastric cancer (carcinoma)Absence ofpepsinogen A3 gene expression in the gastric mucosa
of patients with gastric cancer, 376Dieulafoy's disease associated with early gastric cancer, 267Neural invasion in gastric carcinoma, 137Tissue and serum pepsinogen I and II in gastric cancer identified
using immunohistochemistry and rapid ELISA, 364Gastric inflammation, Improvement of gastric inflammationand resolution of epithelial damage one year after eradicationof Helicobacter pylon, 250
Gastric mucosaHistological findings in gastric mucosa in patients treated with
non-steroidal anti-inflammatory drugs, 553Identification of parietal cells in gastric body mucosa withHMFG-2 monoclonal antibody, 832
Gastric polyposis, Gastric polyposis caused by multiplecarcinoids and early carcinoma, 589
Gastric tube ossification, Heterotopic ossification induced byhypoxia in a retrosternal gastric tube following transhiataloesophagectomy, 177
Gastric ulcers, Serosal reaction in chronic gastric ulcers: animmunohistochemical and ultrastructural study, 226
GastritisChemical gastritis induced by naproxen in the absence of
Helicobacter pyloni infection, 61Helicobacter pylori induced interleukin-8 expression in gastric
epithelial cells is associated with CagA positive phenotype,41
Induction of interleukin-8 secretion from gastric epithelial cellsby a cagA negative isogenic mutant of Helicobacter pylori, 967
The prevalence of lymphoid follicles in Helicobacter pyloriassociated gastritis in patients with ulcers and non-ulcerdyspepsia, 325
Gastrointestinal haemorrhage, Gastrointestinal haemorrhagefrom a jejunal gangliocytic paraganglioma, 84
Gastrointestinal tractEpstein-Barr virus associated lymphoproliferative disorder with
fatal involvement of the gastrointestinal tract in an infant, 390Prospective audit of mucosal biopsy specimens of the
gastrointestinal tract, 936Gel electrophoresis, Changes in transferrin saturation after
treatment with the oral iron chelator deferiprone in patientswith iron overload, 110
Gene expression, Absence of pepsinogen A3 gene expression inthe gastric mucosa of patients with gastric cancer, 376
General practice, Introduction of computer assisted control oforal anticoagulation in general practice, 1144
Genes, Apoptosis in the nervous system: new revelations: leader,7
Genitourinary tract, Pseudoangiosarcomatous carcinoma of thegenitourinary tract, 1059
Germ cell tumour, Langerhans' cell histiocytosis: possibleassociation with malignant germ cell tumour, 963
Glutathione S-transferase B1, Serum glutathione S-transferaseB1 activity as an index of liver function in cystic fibrosis, 771
Goblet cell carcinoid, Combined goblet cell carcinoid andmucinous cystadenoma of the appendix, 869
Gold dental alloy, Gold granuloma after accidental implantation,1070
Gonadotrophin releasing hormone analogue, Degenerativechanges in myometrium simulating diffuse leiomyomatosis aftertreatment with gonadotrophin releasing hormone analogue, 278
Graft versus host diseaseAntigenaemia during acute graft versus host disease, 105Immunohistochemical changes in sigmoid colon after allogeneicand autologous bone marrow transplantation, 308
Gram stain method, Contamination of crystal violet in the Gramstain method: correspondence, 92
GranulomaEffects of treatment on the histopathology of leprosy, 304Granulomatous bone marrow inflammation during treatment
of chronic myeloid leukaemia with interferon alpha-2b, 878Relation of granulomas to lymphatic vessels in Crohn's disease,
335Granulomatous synovitis, Histological changes associated withan artificial anterior cruciate ligament, 556
Granulomatous vasculitis, Idiopathic granulomatous vasculitis:response to immunosuppressive therapy, 579
Growth retardation, Relationship of blood rheology tolipoprotein profile during normal pregnancies and those withintrauterine growth retardation, 571
HHaematological malignancies, Iron metabolism and fungal
infections in patients with haematological malignancies, 223Haematological neoplasms, Routine and specialised techniques
in the diagnosis of haematological neoplasms: leader, 501Haemoglobin, Inaccurate haemoglobin estimation inWaldenstrom's macroglobulinaemia: correspondence, 787
Haemoglobin H inclusion bodies, Comparison ofhaemoglobinH inclusion bodies with embryonic , globin in screening foralpha thalassaemia, 861
Haemophilus influenzae, Avidity of specific IgG antibodieselicited by immunisation against Haemophilus influenzae type b,206
Haemopoietic malignancies, Contribution of immuno-phenotype in the diagnosis and classification of haemopoieticmalignancies: leader, 194
Hairy cell leukaemia, Diagnostic relevance of peripheral bloodimmunocytochemistry in hairy cell leukaemia, 955
Hashimoto's thyroiditis, Immunohistochemical detection ofp53 and Bcl-2 proteins in Hashimoto's thyroiditis and primarythyroid lymphomas, 239
Healthcare staff, Testing healthcare staff for infection with HIVand hepatitis: logistic and ethical considerations: leader, 885
Helicobacter pyloriChemical gastritis induced by naproxen in the absence of
Helicobacter pylori infection, 61
1157
Subject index
Comparison of agar based media for primary isolation ofHelicobacter pylori, 714
Diagnosis of Helicobacter pylori infection by specific gastricmucosal IgA and IgG pylori antibodies, 990
Early ultrastructural changes of antral mucosa with aspirin inthe absence of Helicobacter pylori, 994
Effect of transport medium and transportation time on cultureof Helicobacter pylori from gastric biopsy specimens:correspondence, 91
Failure to detect Helicobacter pylori in nasal mucus in H. pyloripositive dyspeptic patients, 1072
Helicobacter pylori induced interleukin-8 expression in gastricepithelial cells is associated with CagA positive phenotype,41
High prevalence of Helicobacter pylori in saliva demonstrated bya novel PCR assay, 662
Histological findings in gastric mucosa in patients treated withnon-steroidal anti-inflammatory drugs, 553
Improvement of gastric inflammation and resolution of epithelialdamage one year after eradication of Helicobacter pylori, 250
Increased gastric production of interleukin-8 and tumournecrosis factor in patients with Helicobacter pylori infection,133
Induction of interleukin-8 secretion from gastric epithelial cellsby a cagA negative isogenic mutant of Helicobacter pylori, 967
Intragastric urea hydrolysis in children infected with Helicobacterpylori: correspondence, 187
Lymphocytic gastritis and associated small bowel disease: adiffuse lymphocytic gastroenteropathy?, 939
Practical single sample dry latex agglutination test forHelicobacter pylori antibody detection, 969
Prevalence of lymphoid follicles in Helicobacterpylori associatedgastritis in patients with ulcers and non-ulcer dyspepsia, 325
Spectrotypic analysis of antibodies to Helicobacter pylori inpatients with antral gastritis and duodenal ulcer, 1117
Ten year follow up study of lymphocytic gastritis: furtherevidence on Helicobacter pylori as a cause of lymphocyticgastritis and corpus gastritis, 1111
Hepatic artery lymph node, Importance of hepatic artery nodeinvolvement in patients with colorectal liver metastases, 270
Hepatic failure, Acute hepatic and renal failure caused byPneumocystis carinii in patients with AIDS, 975
Hepatic fibrosis, Transient abnormal myelopoiesis accompaniedby hepatic fibrosis in two infants with Down syndrome, 973
Hepatic regeneration, Role of transforming growth factor beta 1on hepatic regeneration and apoptosis in liver diseases, 1093
HepatitisHistological diagnosis of cytomegalovirus hepatitis in liver
allografts, 351Testing healthcare staff for infection with HIV and hepatitis:
logistic and ethical considerations: leader, 885Hepatitis B, Membrane staining for hepatitis B surface antigenon hepatocytes: a sensitive and specific marker of active viralreplication in hepatitis B, 470
Hepatitis B surface antigen, Membrane staining for hepatitisB surface antigen on hepatocytes: a sensitive and specific markerof active viral replication in hepatitis B, 470
Hepatitis C virusHepatitis C virus replication in hepatocellular carcinoma, 880Quantitation ofhepatitis C viral RNA in liver and serum samples
using competitive polymerase chain reaction, 820Hepatocellular carcinoma
Hepatitis C virus replication in hepatocellular carcinoma, 880p53 expression in hepatocellular carcinoma in a population in
Singapore with endemic hepatitis B virus infection, 236Herpes simplex virus, Comparative studies of types 1 and 2
herpes simplex virus infection of cultured normal keratinocytes,75
Heterotopic ossification, Heterotopic ossification induced byhypoxia in a retrosternal gastric tube following transhiataloesophagectomy, 177
Histogenesis, Brenner tumour of the vagina, 678Histology
Effects of treatment on the histopathology of leprosy, 304The clinical value of urinary cytology: 12 years of experience
with 615 patients, 314Histomorphometric parameters, Histomorphometric
classification of postmenopausal osteoporosis: implications forthe management of osteoporosis, 229
HistopathologyJob description of MLSOs: correspondence, 1074
Public perception of histopathology: leader, 398HIV
Detection of mycobacteria in bone marrow biopsy specimenstaken to investigate pyrexia of unknown origin, 706
Differences in androgens of HIV positive patients with andwithout Kaposi sarcoma, 513
Lesser known mycobacteria: leader, 701Management of blood donors whose donations are repeatedly
falsely positive by the HIV antibody screening test, 865Retrospective determination of HIV-1 status by a PCR method
on paraffin wax embedded sections, 733Testing healthcare staff for infection with HIV and hepatitis:
logistic and ethical considerations: leader, 885Tissue diagnosis of intestinal microsporidiosis using a
fluorescent stain with Uvitex 2B, 1009HIV screening, False negative results in enzyme linkedimmunosorbent assays using synthetic HIV antigens, 490
HLA antigens, Expression of HIA-ABC, HLA-DR andintercellular adhesion molecule-I in oesophageal carcinoma,539
HLA typing, HLA typing for DR3 and DR4 using artificalrestriction fragment length polymorphism PCR from archivalDNA, 33
HLA-DR, Effects of treatment on the histopathology of leprosy,304
HMFG-2 monoclonal antibody, Identification of parietal cellsin gastric body mucosa with HMFG-2 monoclonal antibody,832
Hodgkin's diseaseDown-regulation of Epstein-Barr virus nuclear antigen 1 in
Reed-Stemnberg cells of Hodgkin's disease, 845Hodgkin's disease in a patient with common variable
immunodeficiency, 871Immunohistochemical demonstration of different latentmembrane protein-I epitopes of Epstein-Barr virus inlymphoproliferative diseases, 438
Transforming growth factor betal messenger RNA inReed-Stemnberg cells in nodular sclerosing Hodgkin's disease,160
HTLV-1, Use of dried blood spots for the detection andconfirmation of HTLV-I specific antibodies for epidemiologicalpurposes, 904
Human papillomavirusAntibodies to human papillomavirus type 16 E7 related to
clinicopathological data in patients with cervical carcinoma,410
Comparative analysis of human papillomavirus detection byPCR and non-isotopic in situ hybridisation, 415
Detection of integrated human papillomavirus 16 DNA insquamous cell carcinoma of the cervix: correspondence, 393
Diagnosis of genital infection caused by human papillomavirususing in situ hybridisation: the importance of the size of thebiopsy specimen, 57
HPV type 16 in conjunctival and junctional papilloma, dysplasia,and squamous cell carcinoma, 1106
Human papillomavirus in false negative archival cervical smears:implications for screening for cervical cancer, 728
Human papillomaviruses and cervical neoplasia. II. Interactionof HPV with other factors: leader, 1
p53 in human papillomavirus associated anogenital cancers:correspondence, 393
Physical state of human papillomavirus using non-isotopic insitu hybridisation: correspondence, 786
Human T cell lymphotropic virus type I, Use of dried bloodspots for the detection and confirmation of HTLV-1 specificantibodies for epidemiological purposes, 904
HypercalcaemiaHypercalcaemia due to calcium binding IgM paraprotein inWaldenstrom's macroglobulinaemia, 961
Parathyroid hormone related protein and interleukin-6 mRNAexpression in larynx and renal cell carcinomas fromnormocalcaemic and hypercalcaemic patients, 896
Hyperlipidaemia, Relationship of blood rheology to lipoproteinprofile during normal pregnancies and those with intrauterinegrowth retardation, 571
Hypobetalipoproteinaemia, Lipoprotein composition andserum Lp(a) lipoprotein in hypobetalipoproteinaemia, 587
Hypogammaglobulinaemia, Hodgkin's disease in a patient withcommon variable immunodeficiency, 871
Hyposplenism, Functional hyposplenism following allogeneicbone marrow transplantation, 257
1158
Subject index
Hypothyroidism, Thyroid autoantibodies and the response tothyrotropin releasing hormone in patients with subclinicalhypothyroidism, 463
HypoxiaCirculating endothelin- 1 concentrations in patients with chronic
hypoxia, 519Heterotopic ossification induced by hypoxia in a retrosternal
gastric tube following transhiatal oesophagectomy, 177Hysterectomy, Distribution of cervical intraepithelial neoplasia:
are hysterectomy specimens sampled appropriately?, 323
IIdiopathic pulmonary fibrosis, Endothelin-1 in idiopathicpulmonary fibrosis, 330
IgA, Diagnosis of Helicobacter pylon infection by specific gastricmucosal IgA and IgG pylori antibodies, 990
IgE, Specificity and usefulness of an IgE immunosorbentagglutination assay for toxoplasmosis, 64
IgG, Diagnosis of Helicobacter pylori infection by specific gastricmucosal IgA and IgG pylori antibodies, 990
IgG antibodies, Avidity of specific IgG antibodies elicited byimmunisation against Haemophilus influenzae type b, 206
IgM paraprotein, Hypercalcaemia due to calcium binding IgMparaprotein in Waldenstr6m's macroglobulinaemia, 961
Image analysis, Interobserver variation in cell selection for DNAimage cytometry, 616
Image handling, Computerised image handling in pathology:leader, 796
Image processing, Macroscopic assessment of pulmonaryemphysema by image analysis, 318
Immunoassay, Enzyme immunoassays for IgG and IgMantibodies to Toxoplasma gondii based on enhancedchemiluminescence, 652
Immunoblotting, Immunoblotting in the diagnosis of culturenegative endocarditis caused by streptococci and enterococci,1130
Immunocompromised patients, Clinicopathologic implicationsof Epstein-Barr virus related B cell lymphoma inimmunocompromised patients: leader, 287
InmunocytochemistryDiagnostic relevance of peripheral blood immunocytochemistry
in hairy cell leukaemia, 955Immunocytological analysis of the Tn associated antigen 83D4
in serous effusions from patients with cancer: comparisonwith Tn soluble glycoprotein, 433
IrmmunohistochemistryA "quickscore" method for immunohistochemical
semiquantitation: validation for oestrogen receptor in breastcarcinomas, 876
Desmin expression in rhabdomyosarcoma: influence of thedesmin clone and immunohistochemical method, 535
Detection of Ki67 antigen by a new sheep polyclonal antiserum,1138
Immunohistochemical study of topoisomerase II-alphaexpression in primary ductal carcinoma of the breast, 147
Immunohistochemistry in apparently normal bone marrowtrephine specimens from patients with nodal follicularlymphoma, 1035
p53 expression in hepatocellular carcinoma in a population inSingapore with endemic hepatitis B virus infection, 236
Pseudoangiosarcomatous carcinoma of the genitourinary tract,1059
QBEND10 for the diagnosis of myelodysplastic syndromes inroutinely processed bone marrow biopsy specimens, 291:correspondence, 884
Should superheating be used for immunohistochemistry?:correspondence, 883
ImmunophenotypeCD19 and immunophenotype of bone marrow plasma cells inmonoclonal gammopathy of undetermined significance, 548
Contribution of immunophenotype in the diagnosis andclassification of haemopoietic malignancies: leader, 194
Light scatter characteristics of blast cells in acute myeloidleukaemia: association with morphology andimmunophenotype, 456
Splenic lymphoma with circulating villous lymphocytes, 584Inumunophenotypic analysis, Immunophenotypic analysis of
childhood Burkitt's lymphoma in the West Midlands1957-1986, 22
InumunostainingImmunostaining for CD31 and CD34 in Kaposi sarcoma, 1011
Membrane staining for hepatitis B surface antigen onhepatocytes: a sensitive and specific marker of active viralreplication in hepatitis B, 470
In-house media, Enteric media: pre-poured or in-house?, 568In-situ end-labelling, In situ end-labelling, light microscopic
assessment and ultrastructure of apoptosis in lung carcinoma,1017
In situ hybridisationDiagnosis of genital infection caused by human papillomavirus
using in situ hybridisation: the importance of the size of thebiopsy specimen, 57
Fatal adenovirus 32 infection in a bone marrow transplantrecipient, 779
Physical state of human papillomavirus using non-isotopic insitu hybridisation: correspondence, 786
India ink, A rapid and safe method to fix India ink on specimenresection margins: correspondence, 689
Infant, Perinatal and infant postmortem examinations: how wellare we doing?, 998
Infection, Immunological factors and risk of infection in plateauphase myeloma, 260
Infectious disease, Serological testing in a microbiologylaboratory of specimens from patients with suspected infectiousdisease, 358
Inflammatory pseudotumour, Inflammatory pseudotumour oflymph nodes, 37
Intercellular adhesion molecule-1, Expression of HLA-ABC,HLA-DR and intercellular adhesion molecule-i in oesophagealcarcinoma, 539
Interferon, Granulomatous bone marrow inflammation duringtreatment of chronic myeloid leukaemia with interferon alpha-2b, 878
Interferon treatment, Quantitation of hepatitis C viral RNA inliver and serum samples using competitive polymerase chainreaction, 820
Interleukin-1, Concentration of fetal plasma and amniotic fluidinterleukin-1 in pregnancies complicated by preterm prelabouramniorrhexis, 368
Interleukin-6, Parathyroid hormone related protein andinterleukin-6 mRNA expression in larynx and renal cellcarcinomas from normocalcaemic and hypercalcaemic patients,896
Interleukin-8Helicobacter pylori induced interleukin-8 expression in gastric
epithelial cells is associated with CagA positive phenotype,41
Increased gastric production of interleukin-8 and tumournecrosis factor in patients with Helicobacter pylon infection,133
Induction of interleukin-8 secretion from gastric epithelial cellsby a cagA negative isogenic mutant of Helicobacter pylori, 967
Specific increase in interleukin-8 concentrations in dialysis fluidof patients with peritonitis receiving continuous ambulatoryperitoneal dialysis, 115
Interleukins, Effect of interleukins on the proliferation andsurvival of B cell chronic lymphocytic leukaemia cells, 482
Intermediate filament proteins, Cimentin and cytokeratinexpression in nodular hyperplasia and carcinoma of the prostate,1031
Intermediate filaments, Serosal reaction in chronic gastriculcers: an immunohistochemical and ultrastructural study, 226
Internal quality control, Internal quality assurance in a clinicalvirology laboratory. II. Internal quality control, 198
International Normalised Ratio, Effect of thromboplastin andcoagulometer interaction on the precision of the InternationalNormalised Ratio, 13
International Sensitivity Indexes (ISI), An easier alternative toorthogonal regression for calculation of International SensitivityIndexes, 901
Interobserver variationInterobserver variation in cell selection for DNA image
cytometry, 616Malignant mesothelioma of the pleura: interobserver variability,
856Intestinal biopsy, Intraepithelial and lamina propria leucocyte
subsets in inflammatory bowel disease: an immunohistochemicalstudy of colon and rectal biopsy specimens, 743
Intraepithelial lymphocytes, Lymphocytic gastritis andassociated small bowel disease: a diffuse lymphocyticgastroenteropathy?, 939
1159
Subject index
Intrauterine growth retardation, Relationship of bloodrheology to lipoprotein profile during normal pregnancies andthose with intrauterine growth retardation, 571
Intravascular metastatic adenocarcinoma, Recurrentthrombotic occlusions of arteries and veins caused byintravascular metastatic adenocarcinoma: correspondence, 186
Invasive aspergllosis, Use of the Pastorex aspergillus antigenlatex agglutination test for the diagnosis of invasive aspergillosis,210
Invasive thymoma, P-glycoprotein positive, drug resistantinvasive lymphoepithelial thymoma: treatment response tochemotherapy with cyclosporin and quinine, 679
Iron, Postmortem blood ferritin concentrations in sudden infantdeath syndrome, 763
Iron deficiency, Frequency of coincident iron deficiency andbeta-thalassaemia trait in British Asian children, 594
Iron metabolism, Iron metabolism and fungal infections inpatients with haematological malignancies, 223
Iron overload, Changes in transferrin saturation after treatmentwith the oral iron chelator deferiprone in patients with ironoverload, 110
IS6110, IS6110 based amplityping assay and RFLP fingerprintingof clinical isolates of Mycobacterium tuberculosis, 924
Isoprene, Origins of breath isoprene: correspondence, 979
JJejunum, Gastrointestinal haemorrhage from a jejunal
gangliocytic paraganglioma, 84
KK-ATPase, Identification of parietal cells in gastric body mucosa
with HMFG-2 monoclonal antibody, 832K-ras, Molecular markers for diagnostic cytology of neoplasms
in the head region of the pancreas: mutation of K-ras andoverexpression of the p53 protein product, 218
Kaposi sarcomaDifferences in androgens of HIV positive patients with andwithout Kaposi sarcoma, 513
Immunostaining for CD31 and CD34 in Kaposi sarcoma, 1011KBA.62, Production and characterisation of an antimelanomamonoclonal antibody KBA.62 using a new melanoma cell linereactive on paraffin wax embedded sections, 826
KeratinocytesComparative studies of types 1 and 2 herpes simplex virus
infection of cultured normal keratinocytes, 75Epidermal differentiation and dermal changes in healing
following treatment of surgical wounds with sheets of culturedallogeneic keratinocytes, 1087
Keratins, Epidermal differentiation and dermal changes in healingfollowing treatment of surgical wounds with sheets of culturedallogeneic keratinocytes, 1087
Ki67, Circulating Ki67 positive lymphocytes in multiple myelomaand benign monoclonal gammopathy, 835
Ki67 antigenDetection of Ki67 antigen by a new sheep polyclonal antiserum,
1138Oncogene proteins and proliferation antigens in thymomas:
increased expression of epidermal growth factor receptor andKi67 antigen, 447
Kleihauer technique, Flow cytometry in diagnosis andmanagement of large fetomaternal haemorrhage, 1005
LLaboratories
Internal audit in a microbiology laboratory, 560Laboratory turnround time: closing the loop, 372Perceptions of a medical microbiology service: a survey of
laboratory users, 915Laboratory use, Managing test demand by clinicians: computer
assisted guidelines:leader, 98Langerhans' cell histiocytosis, Langerhans' cell histiocytosis:possible association with malignant germ cell tumour, 963
Large intestine, Expression of proliferating cell nuclear antigenin hyperplastic polyps, adenomas and inflammatory cloacogenicpolyps of the large intestine, 46
Larynx cacinoma, Parathyroid hormone related protein andinterleukin-6 mRNA expression in larynx and renal cellcarcinomas from normocalcaemic and hypercalcaemic patients,896
Latent membrane protein-1, Immunohistochemicaldemonstration of different latent membrane protein-i epitopesof Epstein-Barr virus in lymphoproliferative diseases, 438
Latex agglutination, Latex agglutination for rapid detectionof Pseudomonas pseudomallei antigen in urine of patients withmelioidosis, 174
Leiomyomatosis, Degenerative changes in myometriumsimulating diffuse leiomyomatosis after treatment withgonadotrophin releasing hormone analogue, 278
Leprosy, Effects of treatment on the histopathology of leprosy,304
Leucocyte subsets, Intraepithelial and lamina propria leucocytesubsets in inflammatory bowel disease: an immunohistochemicalstudy of colon and rectal biopsy specimens, 743
LeukaemiaChanges in cytomorphology of childhood lymphoblastic
leukaemia at the time of disease relapse, 1051Contribution of immunophenotype in the diagnosis and
classification of haemopoietic malignancies: leader, 194Diagnostic relevance of peripheral blood immunocytochemistry
in hairy cell leukaemia, 955Effect of interleukins on the proliferation and survival of B cell
chronic lymphocytic leukaemia cells, 482Granulomatous bone marrow inflammation during treatment
of chronic myeloid leukaemia with interferon alpha-2b, 878Iron metabolism and fungal infections in patients with
haematological malignancies, 223Light scatter characteristics of blast cells in acute myeloid
leukaemia: association with morphology and immuno-phenotype, 456
QBEND10 for the diagnosis of myelodysplastic syndromes inroutinely processed bone marrow biopsy specimens, 291:correspondence, 884
Routine and specialised techniques in the diagnosis ofhaematological neoplasms: leader, 501
The leukaemic phase of non-Hodgkin's lymphoma: leader, 189Leukaemia immunophenotyping, Leukaemia immunopheno-
typing: effect of antibody source and fluorochrome on antigendetection: correspondence, 186
Light scatter, Light scatter characteristics of blast cells in acutemyeloid leukaemia: association with morphology andimmunophenotype, 456
Lipids, Limited discriminant value of lipoprotein AI, lipoproteinLp(a) and other lipoprotein particles in patients with and withoutearly onset ischaemic heart disease, 70
Lipoblast, Immunohistochemical identification of tumours ofadipocytic differentiation using an antibody to aP2 protein, 950
Lipofuscinosis, Ceroid granulomas in the female genital system,1057
Lipoprotein composition, Lipoprotein composition and serumLp(a) lipoprotein in hypobetalipoproteinaemia, 587
Lipoprotein profile, Relationship of blood rheology tolipoprotein profile during normal pregnancies and those withintrauterine growth retardation, 571
Liposarcoma, Immunohistochemical identification of tumoursof adipocytic differentiation using an antibody to aP2 protein,950
ithium, Histological features of the thyroid gland in a patientwith lithium induced thyrotoxicosis, 582
Liver biopsy, Sampling variability of percutaneous liver biopsyin primary sclerosing cholangitis, 933
Liver diseaseRole oftransforming growth factor betal on hepatic regeneration
and apoptosis in liver diseases, 1093Serum glutathione S-transferase B1 activity as an index of liver
function in cystic fibrosis, 771Liver metastases, Importance of hepatic artery node involvement
in patients with colorectal liver metastases, 270Liver transplant, Histological diagnosis of cytomegalovirus
hepatitis in liver allografts, 351Loss of heterozygosity
Atypical ductal hyperplasia of the breast: clonal proliferationwith loss ofheterozygosity on chromosomes 16q and 17p,611
Loss of heterozygosity on chromosome 11 q in breast cancer,424
Lp(a) lipoprotein, Lipoprotein composition and serum Lp(a)lipoprotein in hypobetalipoproteinaemia, 587
Lung cancer, Interobserver variation in cell selection for DNAimage cytometry, 616
1160
Subject index
Lung carcinoma, In situ end-labelling, light microscopicassessment and ultrastructure of apoptosis in lung carcinoma,-1017Lymph node
Inflammatory pseudotumour of lymph nodes, 37Retrospective determination of HIV-1 status by a PCR methodon paraffin wax embedded sections, 733
Lymphatic vessels, Relation of granulomas to lymphatic vesselsin Crohn's disease, 335
Lymphocyte subsets, Lymphocyte subset counts in skin punctureand venous blood compared, 1137
Lymphocytic gastritisLymphocytic gastritis and associated small bowel disease: a
diffuse lymphocytic gastroenteropathy?, 939Ten year follow up study of lymphocytic gastritis: further
evidence on Helicobacter pylon as a cause of lymphocyticgastritis and corpus gastritis, 1111
Lymphoepithelial carcinoma, Lymphoepithelial carcinoma ofthe salivary gland: in situ detection of Epstein-Barr virus, 1022
Lymphoid follicles, The prevalence of lymphoid follicles inHelicobacter pylori associated gastritis in patients with ulcers andnon-ulcer dyspepsia, 325
Lymphoid tissue, p53, Rb and bcl-2 expression during the cellcycle: a study in phytohaemagglutinin stimulated lymphocytesand microwave irradiated lymphoid tissue sections, 151
LymphomaAssociation of Epstein-Barr virus with sinonasal angiocentric T
cell lymphoma, 946Immunohistochemical analysis ofT cell proliferation in normal
tonsil and B cell lymphoma, 873The biology of low grade MALT lymphoma: leader, 395
Lymphoproliferation, Epstein-Barr virus associatedlymphoproliferative disorder with fatal involvement of thegastrointestinal tract in an infant, 390
Lymphoproliferative disorders, Routine and specialisedtechniques in the diagnosis ofhaematological neoplasms: leader,501
MMalignant mesothelioma, Malignant mesothelioma of the
pleura: interobserver variability, 856MALT lymphoma, Expression of the bcl-2 protein in B celllymphomas arising from mucosa associated lymphoid tissue, 18
Medical microbiology service, Perceptions of a medicalmicrobiology service: a survey of laboratory users, 915
Melanocytic naevi, Nuclear pseudoinclusions in melanocyticnaevi and melanomas, 676
MelanomaApoptotic and mitotic indices in malignant melanoma and basal
cell carcinoma, 242Nuclear pseudoinclusions in melanocytic naevi and melanomas,
676Production and characterisation of an antimelanomamonoclonal antibody KBA.62 using a new melanoma cellline reactive on paraffin wax embedded sections, 826
Melioidosis, Latex agglutination for rapid detection ofPseudomonas pseudomallei antigen in urine of patients withmelioidosis, 174
Mesenchymal tumour, Angiomyxoid tumour in the renalperipelvic tissues with features of aggressive angiomyxoma, 82
MesotheliomaMalignant mesothelioma of the pleura: interobserver variability,856
OV 632 and MOC 31 in the diagnosis of mesothelioma andadenocarcinoma: an assessment of their use in formalin fixedand paraffin wax embedded material, 626
Metastasis, Metastatic breast carcinoma with appearanceresembling micropapillary ductal carcinoma in situ, 380
Methylation, Thiol methyltransferase activity in colonocytes anderythrocyte membranes, 641
MHC class II antigens, Expression of MHC class II antigensby placental villi: no relationship with villitis ofunknown origin,494
MIB-1Immunohistochemical quantitation of oestrogen receptors and
proliferative activity in oestrogen receptor positive breastcancer, 429
Relation between stage, grade, proliferation, and expression ofp53 and CD44 in adenomas and carcinomas of colorectum,1098
Microbe Base data, Quality assessment of Microbe Baseantimicrobial susceptibility data, 1122
Microbiology, Review of a consultant microbiologist's workpractice - an audit: leader, 1082
Microbiology laboratory, Serological testing in a microbiologylaboratory of specimens from patients with suspected infectiousdisease, 358
Microbiology techniques, Internal audit in a microbiologylaboratory, 560
Micropapillary, Metastatic breast carcinoma with appearanceresembling micropapillary ductal carcinoma in situ, 380
Microscopic thymoma, Microscopic thymoma and myastheniagravis, 682
Microscopy, Routine urinalysis in renal transplant patients, 383Microsporidia, Detection and identification of gastrointestinal
microsporidia using non-invasive techniques, 725Microsporidiosis, Tissue diagnosis of intestinal microsporidiosis
using a fluorescent stain with Uvitex 2B, 1009Microwave heating, Immunohistochemical staining of plasticembedded bone marrow trephine biopsy specimens aftermicrowave heating, 840
Mitomycinlifosfamide/cisplatin, Lack of correlation of P-glycoprotein expression with response to MIC chemotherapy inoesophageal cancer, 1064
MitosisApoptotic and mitotic indices in malignant melanoma and basal
cell carcinoma, 242Quantification of proliferative activity in colorectal adenomasby mitotic counts: relationship to degree of dysplasia andhistological type, 620
MLSOs, Job description of MLSOs: correspondence, 1074MOC 31, OV 632 and MOC 31 in the diagnosis of mesotheliomaand adenocarcinoma: an assessment of their use in formalinfixed and paraffin wax embedded material, 626
Molecular genetics, Molecular genetics offamilial breast-ovariancancer: leader, 789
Monoclonal antibody(ies)Comparison of three methods for culture confirmation of
Neisseria gonorrhoeae strains currently circulating in the UK,919
Immunohistochemical demonstration of different latentmembrane protein-i epitopes of Epstein-Barr virus inlymphoproliferative diseases, 438
Monoclonal gammopathyCD19 and immunophenotype of bone marrow plasma cells inmonoclonal gammopathy of undetermined significance, 548
Plasma cell proliferation in monoclonal gammopathies:measurement using BU-1 antibody in flow cytometry andmicroscopy: comparison with serum thymidine kinase, 477
Monoclonal gammopathy of undetermined significance,Circulating Ki67 positive lymphocytes in multiple myeloma andbenign monoclonal gammopathy, 835
Monoclonality, The polymerase chain reaction in thedemonstration of monoclonality in T cell lymphomas, 1045
Monocyte activation, Activated phenotype in neutrophils andmonocytes from patients with primary proliferativepolycythaemia, 525
Monocyte esterase deficiency, Organophosphates andmonocyte esterase deficiency, 768: correction, 1074
MOv18, Distribution of OV-TL 3 and MOv18 in normal andmalignant ovarian tissue, 631
Mucinous adenoma, Papillary mucinous adenoma arising inadenomyomatous hyperplasia of the gall bladder, 965
Mucinous cystadenoma, Combined goblet cell carcinoid andmucinous cystadenoma of the appendix, 869
Mucosa associated lymphoid tissueExpression of the bcl-2 protein in B cell lymphomas arisingfrom mucosa associated lymphoid tissue, 18
The biology of low grade MALT lymphoma: leader, 395Mucosal biopsy specimens, Prospective audit of mucosal biopsy
specimens of the gastrointestinal tract, 936Multidrug resistanceLack of correlation of P-glycoprotein expression with response
to MIC chemotherapy in oesophageal cancer, 1064P-glycoprotein positive, drug resistant invasive lymphoepithelialthymoma: treatment response to chemotherapy withcyclosporin and quinine, 679
Multiple myelomaCD19 and immunophenotype of bone marrow plasma cells inmonoclonal gammopathy of undetermined significance, 548
1161
Subject index
Circulating Ki67 positive lymphocytes in multiple myeloma andbenign monoclonal gammopathy, 835
Muscular dystrophies, Recent advances in muscular dystrophiesand myopathies: leader, 597
Myasthenia gravisMicroscopic thymoma and myasthenia gravis, 682Oncogene proteins and proliferation antigens in thymomas:
increased expression of epidermal growth factor receptor andKi67 antigen, 447
MycobacteriaCommercially available versus home produced egg media for
isolation of mycobacteria, 564Detection of mycobacteria in bone marrow biopsy specimens
taken to investigate pyrexia of unknown origin, 706Lesser known mycobacteria: leader, 701Multiplex PCR for identifying mycobacterial isolates, 203
Mycobactenium tuberculosisIS6110 based amplityping assay and RFLP fingerprinting of
clinical isolates of Mycobacterium tuberculosis, 924Routine application of the polymerase chain reaction for
detection ofMycobacterium tuberculosis in clinical samples, 810Myelodysplasia, QBEND10 for the diagnosis of myelodysplastic
syndromes in routinely processed bone marrow biopsyspecimens, 291: correspondence, 884
Myelodysplastic syndromes, Routine and specialisedtechniques in the diagnosis of haematological neoplasms: leader,501
MyelofibrosisOsteolytic bone lesions in a patient with idiopathic myelofibrosisand bronchial carcinoma, 867
Transient abnormal myelopoiesis accompanied by hepaticfibrosis in two infants with Down syndrome, 973
Myeloma, Immunological factors and risk of infection in plateauphase myeloma, 260
Myeloproliferative disorders, Routine and specialisedtechniques in the diagnosis of haematological neoplasms: leader,501
Myocardial infarction, Biochemical assessment of acutemyocardial ischaemia, 124
Myoepithelial carcinoma, Malignant myoepithelioma(myoepithelial carcinoma) of the breast: a detailed cytokeratinstudy, 164
Myopathies, Recent advances in muscular dystrophies andmyopathies: leader, 597
Myxomas, S100, alpha-smooth muscle actin and cytokeratin 19immunohistochemistry in odontogenic and soft tissue myxomas,759
NNaproxen, Chemical gastritis induced by naproxen in the absence
of Helicobacter pylori infection, 61Nasal mucus, Failure to detect Helicobacter pylon in nasal mucus
in H. pylori positive dyspeptic patients, 1072Neck movement, A necropsy and histomorphometric study of
abnormalities in the course of the vertebral artery associatedwith ossified stylohyoid ligaments, 637
Necrobiotic granulomasNecrobiotic granulomas of the urogenital system: correspondence,
185, 690NecropsyCan histopathologists diagnose bronchopneumonia?, 120Cytodiagnosis and the necropsy, 443Have declining clinical necropsy rates reduced the contribution
of necropsy to medical research?, 402Perinatal and infant postmortem examinations: how well are we
doing?, 998Public perceptions of necropsy: leader, 497
Needle biopsy, Macroscopic examination of prostatic specimens:leader, 693
Neisseria gonorrhoeaeAcute gonococcal arthritis: an unusual host and pathogen
combination, 86Comparison of three methods for culture confirmation of
Neisseria gonorrhoeae strains currently circulating in the UK,919
Duplex PCR system for simultaneous detection of Neisseriagonorrhoeae and Chlamydia trachomatis in clinical specimens,101
Value of screening for oro-pharyngeal Chlamydia trachomatisinfection, 658
Neomycin blood agar, Neomycin blood agar as a selectivemedium for vancomycin resistant Enterococcus faecium, 1068
Neoplastic disease, Organophosphates and monocyte esterasedeficiency, 768: correction, 1074
Nervous system, Apoptosis in the nervous system: newrevelations: leader, 7
Neural invasion, Neural invasion in gastric carcinoma, 137Neutropenia, Corynebactenium aquaticum septicaemia in a
neutropenic patient, 971Neutrophil activation, Activated phenotype in neutrophils andmonocytes from patients with primary proliferativepolycythaemia, 525
Neutrophil cytoplasmic antigens, Detection of autoantibodiesto neutrophil cytoplasmic antigens: correspondence, 785
Nodal follicular lymphoma, Immunohistochemistry inapparently normal bone marrow trephine specimens frompatients with nodal follicular lymphoma, 1035
Nodular hyperplasia, Cimentin and cytokeratin expression innodular hyperplasia and carcinoma of the prostate, 1031
Non-Hodgkin's lymphomaLongstanding proliferation of CD3 negative large granular
lymphocytes preceding the development of high grade non-Hodgkin's lymphoma, 672
The leukaemic phase of non-Hodgkin's lymphoma: leader, 189Non-insulin dependendent diabetes mellitus, Rapid and safe
determination of human apolipoprotein E genotypes byminiaturised SDS-PAGE in non-insulin dependent diabetesmellitus, 295
Non-isotopic in situ hybridisation, Comparative analysis ofhuman papillomavirus detection by PCR and non-isotopic insitu hybridisation, 415
Non-neoplastic glandular structures, Non-neoplasticglandular structures in bone marrow: a technical artefact, 1141
Non-steroidal anti-inflammatory drugs, Histological findingsin gastric mucosa in patients treated with non-steroidal anti-inflammatory drugs, 553
Non-ulcer dyspepsia, The prevalence of lymphoid follicles inHelicobacter pylon associated gastritis in patients with ulcers andnon-ulcer dyspepsia, 325
Northern blotting, Chromogranin positive cells in colorectalcarcinoma and transitional mucosa, 754
Notices, 94, 187, 282, 394, 496, 596, 692, 788, 884, 980, 1074
0Observer reliability, Observer reliability in assessing placental
maturity by histology, 420Odontogenic myxoma, S100, alpha-smooth muscle actin and
cytokeratin 19 immunohistochemistry in odontogenic and softtissue myxomas, 759
Oesophageal carcinomaExpression of HLA-ABC, HIA-DR and intercellular adhesion
molecule-l in oesophageal carcinoma, 539Lack of correlation of P-glycoprotein expression with response
to MIC chemotherapy in oesophageal cancer, 1064Oesophageal neoplasma, p53 protein accumulation in
oesophageal squamous cell carcinomas and precancerouslesions, 531
Oesophagus, Heterotopic ossification induced by hypoxia in aretrostemal gastric tube following transhiatal oesophagectomy,177
Oestrogen receptorA "quickscore" method for immunohistochemical
semiquantitation: validation for oestrogen receptor in breastcarcinomas, 876
Immunohistochemical quantitation of oestrogen receptors andproliferative activity in oestrogen receptor positive breastcancer, 429
Oncogene expression, Apocrine adenosis: a precursor ofaggressive breast cancer?, 737
Oncogenes, Oncogene proteins and proliferation antigens inthymomas: increased expression of epidermal growth factorreceptor and Ki67 antigen, 447
Oncology centre, Audit of tumour histopathology reviewed bya regional oncology centre, 245
Oral anticoagulant therapy, An easier alternative to orthogonalregression for calculation of International Sensitivity Indexes,901
Oral mucosa, Gold granuloma after accidental implantation,1070
Organophosphates, Organophosphates and monocyte esterasedeficiency, 768: correction, 1074
1162
Subject index
Oro-genital contact, Value of screening for oro-pharyngealChlamydia trachomatis infection, 658
Orthogonal regression, An easier altemative to orthogonalregression for calculation of International Sensitivity Indexes,901
Orthostatic hypotension, Orthostatic hypotension andvasodilatory peptides in bronchial carcinoma, 1102
Ossified stylohyoid ligaments, A necropsy and histo-morphometric study of abnormalities in the course of thevertebral artery associated with ossified stylohyoid ligaments,637
Osteolytic lesions, Osteolytic bone lesions in a patient withidiopathic myelofibrosis and bronchial carcinoma, 867
Osteoporosis, Histomorphometric classification of postmeno-
pausal osteoporosis: implications for the management ofosteoporosis, 229
Out-of-hours service, Do blood cultures need continuousmonitoring so that clinical action can be taken outside normalworking hours?, 1067
OV 632, OV 632 and MOC 31 in the diagnosis of mesotheliomaand adenocarcinoma: an assessment of their use in formalinfixed and paraffin wax embedded material, 626
OV-TL 3, Distribution of OV-TL 3 and MOv18 in normal andmalignant ovarian tissue, 631
Ovarian carcinoma, Distribution of OV-TL 3 and MOv18 innormal and malignant ovarian tissue, 631
pp53
Immunohistochemical detection of p53 and Bcl-2 proteins inHashimoto's thyroiditis and primary thyroid lymphomas, 239
Molecular markers for diagnostic cytology of neoplasms inthe head region of the pancreas: mutation of K-ras andoverexpression of the p53 protein product, 218
p53, Rb and bcl-2 expression during the cell cycle: a study inphytohaemagglutinin stimulated lymphocytes and microwaveirradiated lymphoid tissue sections, 151
p53 expression in hepatocellular carcinoma in a population inSingapore with endemic hepatitis B virus infection, 236
p53 in human papillomavirus associated anogenital cancers:
correspondence, 393p53 protein accumulation in oesophageal squamous cell
carcinomas and precancerous lesions, 531Relation between stage, grade, proliferation, and expression ofp53 and CD44 in adenomas and carcinomas of colorectum,1098
P-glycoproteinLack of correlation of P-glycoprotein expression with response
to MIC chemotherapy in oesophageal cancer, 1064P-glycoprotein positive, drug resistant invasive lymphoepithelialthymoma: treatment response to chemotherapy withcyclosporin and quinine, 679
Paget's disease, Paget's disease of the breast: correspondence, 393Pancreatic cancer, Molecular markers for diagnostic cytology
of neoplasms in the head region of the pancreas: mutation ofK-ras and overexpression of the p53 protein product, 218
Papillary microcarcinoma of the thyroid, Occult papillarymicrocarcinoma of the thyroid: a potential pitfall of fine needleaspiration cytology? Is it possible to avoid it?: correspondence,185
Papilloma, HPV type 16 in conjunctival and junctional papilloma,dysplasia, and squamous cell carcinoma, 1106
Paraffin wax sectionsProduction and characterisation of an antimelanomamonoclonal antibody KBA.62 using a new melanoma cellline reactive on paraffin wax embedded sections, 826
Retrospective determination of HIV-1 status by a PCR methodon paraffin wax embedded sections, 733
Parathyroid hormone related proteinParathyroid hormone related protein and interleukin-6 mRNA
expression in larynx and renal cell carcinomas fromnormocalcaemic and hypercalcaemic patients, 896
Parathyroid hormone related protein in oral squamous cellcarcinomas invading the mandible, 300
Parietal cells, Identification of parietal cells in gastric bodymucosa with HMFG-2 monoclonal antibody, 832
Parvovirus B19, Anticomplementary activity in serum samplesfrom patients with acute parvovirus B19 infection, 493
PasteureUa multocida, Waterhouse-Friderichsen syndromecomplicating primary biliary sepsis due to Pasteurella multocidain a patient with cirrhosis, 775
Pastorex AspergiUus antigen test, Clinical evaluation andreproducibility of the Pastorex Aspergilus antigen latexagglutination test for diagnosing invasive aspergillosis, 474
Pattern recognition, Volatile organic compounds in the breathof patients with schizophrenia, 466
Pelvic recurrence, Influence of local peritoneal involvement onpelvic recurrence and prognosis in rectal cancer, 849
Pepsinogen, Absence of pepsinogen A3 gene expression in thegastric mucosa of patients with gastric cancer, 376
Pepsinogen I and II, Tissue and serum pepsinogen I and II ingastric cancer identified using immunohistochemistry and rapidELISA, 364
Pericardial fluid, Biochemical assessment of acute myocardialischaemia, 124
Perinatal, Perinatal and infant postmortem examinations: howwell are we doing?, 998
Peritoneal dialysis, Specific increase in interleukin-8concentrations in dialysis fluid of patients with peritonitisreceiving continuous ambulatory peritoneal dialysis, 115
Peritoneal involvement, Influence of local peritonealinvolvement on pelvic recurrence and prognosis in rectal cancer,849
Peritonitis, Specific increase in interleukin-8 concentrations indialysis fluid of patients with peritonitis receiving continuousambulatory peritoneal dialysis, 115
Pharmacists, Evaluation of anticoagulant control in a pharmacistoperated anticoagulant clinic, 545
Placental maturity, Observer reliability in assessing placentalmaturity by histology, 420
Placental pathology, Expression of MHC class II antigens byplacental villi: no relationship with villitis of unknown origin,494
Plastic embedding, Immunohistochemical staining of plasticembedded bone marrow trephine biopsy specimens aftermicrowave heating, 840
Plateau phase myeloma, Immunological factors and risk ofinfection in plateau phase myeloma, 260
Pleura, Malignant mesothelioma of the pleura: interobservervariability, 856
Pneumocystis carinii, Acute hepatic and renal failure causedby Pneumocystis carinii in patients with AIDS, 975
Pneumocystis caninii pneumonia, Routine diagnosis ofPneumocystis carinii pneumonia: correspondence, 91
Polyarthralgia, Microbiological investigation of polyarthralgia,777
Polymerase chain reactionAbsence of pepsinogen A3 gene expression in the gastricimucosa
of patients with gastric cancer, 376Chlamydia trachomatis and ectopic pregnancy: retrospective
analysis of salpingectomy specimens, endometrial biopsies,and cervical smears, 815
Comparative analysis of human papillomavirus detection byPCR and non-isotopic in situ hybridisation, 415
Detection of cytomegalovirus using PCR in serum from renaltransplant recipients, 575
Hepatitis C virus replication in hepatocellular carcinoma, 880High prevalence of Helicobacter pylori in saliva demonstrated by
a novel PCR assay, 662Human papillomavirus in false negative archival cervical smears:
implications for screening for cervical cancer, 728IS6 110 based amplityping assay and RFLP fingerprinting of
clinical isolates of Mycobacterium tuberculosis, 924Management of blood donors whose donations are repeatedly
falsely positive by the HIV antibody screening test, 865Molecular markers for diagnostic cytology of neoplasms in
the head region of the pancreas: mutation of K-ras andoverexpression of the p53 protein product, 218
Mulitplex PCR for identifying mycobacterial isolates, 203Quantitation ofhepatitis C viral RNA in liver and serum samples
using competitive polymerase chain reaction, 820Retrospective determination of HIV-1 status by a PCR methodon paraffin wax embedded sections, 733
Routine application of the polymerase chain reaction fordetection ofMycobacterium tuberculosis in clinical samples, 810
The polymerase chain reaction in the demonstration ofmonoclonality in T cell lymphomas, 1045
Value of screening for oro-pharyngeal Chlamydia trachomatisinfection, 658
Polyps, Expression of proliferating cell nuclear antigen inhyperplastic polyps, adenomas and inflammatory cloacogenicpolyps of the large intestine, 46
1163
Subject index
Post-mortem, Public perceptions of necropsy: leader, 497Post-transplant lymphoproliferative disease, Tissue
polypeptide specific antigen for the detection oflymphoproliferative diseases induced by cyclosporin, 1039
Pregnancy, Specificity and usefulness of an IgE immunosorbentagglutination assay for toxoplasmosis, 64
Prenatal diagnosis, Screening criteria for beta thalassaemia traitin pregnant women, 1054
Preterm prelabour amniorrhexis, Concentration of fetalplasma and amniotic fluid interleukin-I in pregnanciescomplicated by preterm prelabour amniorrhexis, 368
Primary polycythaemia, Activated phenotype in neutrophilsand monocytes from patients with primary proliferativepolycythaemia, 525
Primary sclerosing cholangitis, Sampling variability ofpercutaneous liver biopsy in primary sclerosing cholangitis, 933
Procollagen type 1, Enhanced expression of type I procollagenand transforming growth factor-beta in tuberculin induceddelayed type hypersensitivity, 339
Proctocolectomy, Effect of proctocolectomy on serumantineutrophil cytoplasmic antibodies in patients with chroniculcerative colitis, 645
Prognosis, Prognostic factors in primary breast carcinoma: leader,981
Proliferating cell nuclear antigen, Expression of proliferatingcell nuclear antigen in hyperplastic polyps, adenomas andinflammatory cloacogenic polyps of the large intestine, 46
ProliferationAtypical ductal hyperplasia of the breast: clonal proliferation
with loss of heterozygosity on chromosomes 16q andl 17p,611
Effect of interleukins on the proliferation and survival of B cellchronic lymphocytic leukaemia cells, 482
Immunohistochemical analysis ofT cell proliferation in normaltonsil and B cell lymphoma, 873
Longstanding proliferation of CD3 negative large granularlymphocytes preceding the development of high grade non-Hodgkin's lymphoma, 672
Quantification of proliferative activity in colorectal adenomasby mitotic counts: relationship to degree of dysplasia andhistological type, 620
Proliferative activity, Immunohistochemical quantitation ofoestrogen receptors and proliferative activity in oestrogenreceptor positive breast cancer, 42.9
ProstateCimentin and cytokeratin expression in nodular hyperplasia and
carcinoma of the prostate, 1031Macroscopic examination of prostatic specimens: leader, 693
Prosthetic cruciate ligament, Histological changes associatedwith an artificial anterior cruciate ligament, 556
Protein S, Acquired protein S deficiency in a patient with systemiclupus erythematosus causing central retinal vein thrombosis,387
Pseudoanosarcomtous a, Pseudoangiosarcomatouscarcinoma of the genitourinary tract, 1059
Pseudoclusters of infection, "Pseudoclusters" and typing byrandom amplification of polymorphic DNA of Aspergillusfumigatus, 183
Pseudoinclusions, Nuclear pseudoinclusions in melanocyticnaevi and melanomas, 676
Pseudomonas fluorescens, Rate of growth of Pseudomonasfluorescens in donated blood, 717
Pseudomonas pseudomaUei, Latex agglutination for rapiddetection ofPseudomonaspseudomallei antigen in urine ofpatientswith melioidosis, 174
Pulmonary emphysema, Macroscopic assessment ofpulmonaryemphysema by image analysis, 318
Pulmonary thromboembolism, Seasonal variation in thenecropsy incidence of pulmonary thromboembolism:correspondence, 883
Pyrexia ofunknown origin, Detection of mycobacteria in bonemarrow biopsy specimens taken to investigate pyrexia ofunknown origin, 706
QQBEND10, QBEND10 for the diagnosis of myelodysplasticsyndromes in routinely processed bone marrow biopsyspecimens, 291: correspondence, 884
Quality assessment, Internal quality assurance in a clinicalvirology laboratory. I. Internal quality assessment, 168
Quality assurance
Composition of cervical smears in patients with and without acervical ectropion, 408
Intemal audit in a microbiology laboratory, 560Internal quality assurance in a clinical virology laboratory. I.
Internal quality assessment, 168Internal quality assurance in a clinical virology laboratory. II.
Internal quality control, 198Quality control, Role ofre-screening of cervical smears in internal
quality control, 1002Quaity microbiology service, Perceptions of a medical
microbiology service: a survey of Iaboratory users, 915Quant, A proposed SI unit for number: corespondence, 187Quantification, Simple method for quantifying viable bacterialnumbers in sputum, 719
Quickscore, A "quickscore" method for immunohistochemicalsemiquantitation: validation for oestrogen receptor in breastcarcinomas, 876
RRAPD typing, "Pseudoclusters" and typing by random
amplification of polymorphic DNA of Aspergilusf;nigatus, 183Rb, p53, Rb and bcl-2 expression during the cell cycle: a study
in phytohaemagglutinin stimulated lymphocytes and microwaveirradiated lymphoid tissue sections, 151
Re-screening, Role of re-screening of cervical smears in internalquality control, 1002
Rectal cancer, Influence oflocal peritoneal involvement on pelvicrecurrence and prognosis in rectal cancer, 849
Red cell pits, Functional hyposplenism foHlowing allogeneic bonemarrow transplantation, 257
Reed-Sternberg cellsDown-regulation of Epstein-Barr virus nuclear antigen I in
Reed-Stemnberg cells of Hodgkin's disease, 845Transforming growth factor betal messenger RNA in
Reed-Stemnberg cells in nodular sclerosing Hodgkin's disease,160
Regional oncology centre, Audit of tumour pathology reviewedby a regional oncology centre: correspondence, 690
Renal cell carcinoma, Parathyroid hormone related proteinand interleukin-6 mRNA expression in larynx and renal cellcarcinomas from normocalcaemic and hypercalcaemic patients,896
Renal failureAcute hepatic and renal failure caused by Pneumocystis carinni
in patients with AIDS, 975Renal failure in a patient with chronic lymphocytic leukaemia
treated with fludarabine, 181Renal peripehis, Angiomyxoid tumour in the renal peripelvic
tissues with features of aggressive angiomyxoma, 82Renal transplant, Detection of cytomegalovirus using PCR inserum from renal transplant recipients, 575
Renal transplant screening, Routine urinalysis in renaltransplant patients, 383
Replication, Hepatitis C virus replication in hepatocellularcarcnoma, 880
Research, Have declining clinical necropsy rates reduced thecontribution of necropsy to medical research?, 402
Respirtory disease, Circulating endothelin-l concentrations inpatients with chronic hypoxia, 519
Retropubic prostatectomy, Macroscopic examination ofprostatic specimens: leader, 693
RFLP analysis, IS6110 based amplityping assay and RFLPfingerprinting of clinical isolates of Mycobacterium tuberculosis,924
Rhabdomyosarcoma, Desmin expression in rhabdomyo-sarcoma: influence of the desmin clone andimmunohistochemical method, 535
Risk factors, Immunological factors and risk of infection inplateau phase myeloma, 260
SSaccular aneurysms, Subarachnoid haemorrhage and mythsabout saccular aneurysms: leader, 1078
Saliva, High prevalence of Heicobacter pylon in salivademonstrated by a novel PCR assay, 662
Salivary gland, Lymphoepithelial carcinoma ofthe salivary gland:in situ detection of Epstein-Barr virus, 1022
Sampling variabity, Sampling variability of percutaneous liverbiopsy in primary sclerosing cholangitis, 933
Saudi Arabia, Variation in serum electrolytes and enzymeconcentrations in patients with sickle cell disease, 648
1164
Subject index
Schizophrenia, Volatile organic compounds in the breath ofpatients with schizophrenia, 466
ScreeningHuman papillomavirus in false negative archival cervical smears:
implications for screening for cervical cancer, 728Multifactorial audit of invasive cervical cancer: key lessons for
the National Screening Programme, 405: comspondence, 785Role ofre-screening ofcervical smears in internal quality control,
1002SDS-PAGE, Rapid and safe determination of human
apolipoprotein E genotypes by miniaturised SDS-PAGE in non-insulin dependent diabetes mellitus, 295
Seasonal variationSeasonal variation in the necropsy incidence of pulmonarythromboembolism: correspondence, 883
Seasonal variation in the necropsy incidence of pulmonarythromboembolism in Hong Kong, 578
Semiautomated analysis, Evaluation of the API-Campy Systemin the biochemical identification of hippurate negativecampylobacter strains isolated from faeces, 683
Septicaemia, Corynebacterium aquaticum septicaemia in aneutropenic patient, 971
Serodiagnosis, Immunoblotting in the diagnosis of culturenegative endocarditis caused by streptococci and enterococci,1130
Serological markers, Serological markers to differentiatebetween ulcerative colitis and Crohn's disease, 346
Serological testing, Serological testing in a microbiologylaboratory of specimens from patients with suspected infectiousdisease, 358
Serosa, Serosal reaction in chronic gastric ulcers: animmunohistochemical and ultrastructural study, 226
SI unit, A proposed SI unit for number: correspondence, 187Siclde cell disease, Variation in serum electrolytes and enzyme
concentrations in patients with sickle cell disease, 648Sigmoid colon, Immunohistochemical changes in sigmoid colon
after allogeneic and autologous bone marrow transplantation,308
Signet-ring cell lymphoma, B cell signet-ring cell lymphomaof bone marrow, 275
Simultaneous detection, Duplex PCR system for simultaneousdetection of Neisseria gonorrhoeae and Chlamydia trachomatis inclinical specimens, 101
Sinonasal lymphomas, Association of Epstein-Barr virus withsinonasal angiocentric T cell lymphoma, 946
Skin puncture blood, Lymphocyte subset counts in sldn punctureand venous blood compared, 1137
Slice radiography, Specimen slice radiography ofcancer in breastconserving excisions, 1028
Small intestinal permeability, Lymphocytic gastritis andassociated small bowel disease: a diffuse lymphocyticgastroenteropathy?, 939
Smoking, Free radical activity in young adult cigarette smokers,385
Smooth muscle actin, S100, alpha-smooth muscle actin andcytokeratin 19 immunohistochemistry in odontogenic and softtissue myxomas, 759
Specimen resection margins, A rapid and safe method to fixIndia ink on specimen resection margins: correspondence, 689
Splenic lymphoma, Splenic lymphoma with circulating villouslymphocytes, 584
Sputum, Simple method for quantifing viable bacterial numbersin sputum, 719
Squamous cell carcinomaDetection of integrated human papillomavirus 16 DNA insquamous cell carcinoma of the cervix: correspondence, 393
HPV type 16 in conjunctival and junctional papilloma, dysplasia,and squamous cell carcinoma, 1106
p53 protein accumulation in oesophageal squamous cellcarcinomas and precancerous lesions, 531
Parathyroid hormone related protein and interleukin-6 mRNAexpression in larynx and renal cell carcinomas fromnormocalcaemic and hypercalcaemic patients, 896
Parathyroid hormone related protein in oral squamous cellcarcinomas invading the mandible, 300
Staphylococci, Lethal synergy between toxins of staphylococciand enterobacteria: implications for sudden infant deathsyndrome, 929
Steroid hormone receptors, Steroid hormone receptors andtheir clinical significance in cancer: leader, 890
Streptococcus pneumoniae, Detection of C-polysaccharide inserum of patients with Streptococcus pneumoniae bacteraemia,803
Stromal sarcoma, Uterine stromal sarcoma following tamoxifentreatment: correspondence, 596
Subarachnoid haemorrhage, Subarachnoid haemorrhage andmyths about saccular aneurysms: leader, 1078
Sudden death, Sudden death from coronary artery dissection,781
Sudden infant death syndromeLethal synergy between toxins of staphylococci and
enterobacteria: implications for sudden infant deathsyndrome, 929
Postmortem blood ferritin concentrations in sudden infant deathsyndrome, 763
Superheating, Should superheating be used for immuno-histochemistry?: correspondence, 883
Survey, Perceptions of a medical microbiology service: a surveyof laboratory users, 915
Synergy, Lethal synergy between toxins of staphylococci andenterobacteria: implications for sudden infant death syndrome,929
Synthetic HIV antigens, False negative results in enzyme linkedimmunosorbent assays using synthetic HIV antigens, 490
Systemic lupus erythematosus, Acquired protein S deficiencyin a patient with systemic lupus erythematosus causing centralretinal vein thrombosis, 387
TT cell, Immunohistochemical analysis of T cell proliferation innormal tonsil and B cell lymphoma, 873
T cell lymphoma, The polymerase chain reaction in thedemonstration of monoclonality in T cell lymphomas, 1045
T cell receptor beta and gamma, The polymerase chain reactionin the demonstration of monoclonality in T cell lymphomas,1045
Tachyzoite antigen, Serological reactivity against cyst andtachyzoite antigens of Toxoplasma gondii determined by FAST-ELISA, 908
Tamoxifen, Uterine stromal sarcoma following tamoxifentreatment: correspondence, 596
Targeting, Distribution of OV-TL 3 and MOv18 in normal andmalignant ovarian tissue, 631
Technicon H.2 counter, Screening criteria for beta thalassaemiatrait in pregnant women, 1054
Test demand, Managing test demand by clinicians: computerassisted guidelines: leader, 98
Testicular vasculitis, Isolated testicular vasculitis mimicking atesticular neoplasm: correspondence, 496
Testing regimes, Testing healthcare staff for infection with HIVand hepatitis: logistic and ethical considerations: leader, 885
ThalassaemiaComparison ofhaemoglobin H inclusion bodies with embryonic
F, globin in screening for alpha thalassaemia, 861Frequency of coincident iron deficiency and beta-thalassaemia
trait in British Asian children, 594Thalassaemia trait, Screening criteria for beta thalassaemia trait
in pregnant women, 1054Thiol methyltransferase, Thiol methyltransferase activity in
colonocytes and erythrocyte membranes, 641Thromboembolism, Seasonal variation in the necropsy incidence
of pulmonary thromboembolism in Hong Kong, 578Thromboplastin, Effect of thromboplastin and coagulometer
interaction on the precision of the International NormalisedRatio, 13
Thrombotic occlusions, Recurrent thrombotic occlusions ofarteries and veins caused by intravascular metastaticadenocarcinoma: correspondence, 186
Thymidine kinase, Plasma cell proliferation in monoclonalgammopathies: measurement using BU-1 antibody in flowcytometry and microscopy: comparison with serum thymidinekinase, 477
Thymoma, Oncogene proteins and proliferation antigens inthymomas: increased expression of epidermal growth factorreceptor and Ki67 antigen, 447
Thyroid histology, Histological features of the thyroid gland ina patient with lithium induced thyrotoxicosis, 582
Thyroid lymphomas, Immunohistochemical detection of p53and Bcl-2 proteins in Hashimoto's thyroiditis and primarythyroid lymphomas, 239
1165
Subject index
Thyroid stimulating hormone, Thyroid autoantibodies and theresponse to thyrotropin releasing hormone in patients withsubclinical hypothyroidism, 463
Thyrotoxicosis, Histological features of the thyroid gland in apatient with lithium induced thyrotoxicosis, 582
Thyrotropin releasing hormone, Thyroid autoantibodies andthe response to thyrotropin releasing hormone in patients withsubclinical hypothyroidism, 463
Tissue polypeptide specific antigen, Tissue polypeptide specificantigen for the detection oflymphoproliferative diseases inducedby cyclosporin, 1039
Tissue processing, Distribution of cervical intraepithelialneoplasia: are hysterectomy specimens sampled appropriately?,323
Tn associated antigen, Immunocytological analysis of the Tnassociated antigen 83D4 in serous effusions from patients withcancer: comparison with Tn soluble glycoprotein, 433
Topoisomerase IH-alpha, Immunohistochemical study oftopoisomerase II-alpha expression in primary ductal carcinomaof the breast, 147
Toxins, Lethal synergy between toxins of staphylococci andenterobacteria: implications for sudden infant death syndrome,929
Toxoplasma antibodies, Enzyme immunoassays for IgG andIgM antibodies to Toxoplasma gondii based on enhancedchemiluminescence, 652
Toxoplasma gondii, Serological reactivity against cyst andtachyzoite antigens of Toxoplasma gondii determined by FAST-ELISA, 908
Toxoplasma specific IgA, The value ofToxoplasma specific IgAin diagnosis: correspondence, 689
Toxoplasmosis, Specificity and usefulness of an IgEimmunosorbent agglutination assay for toxoplasmosis, 64
Transferrin, Changes in transferrin saturation after treatmentwith the oral iron chelator deferiprone in patients with ironoverload, 110
Transforming growth factor-beta, Enhanced expression oftype1 procollagen and transforming growth factor-beta in tuberculininduced delayed type hypersensitivity, 339
Transforming growth factor betalRole oftransforming growth factor betal on hepatic regenerationand apoptosis in liver diseases, 1093
Transforming growth factor beta 1 messenger RNA inReed-Stemnberg cells in nodular sclerosing Hodgkin's disease,160
Transient abnormal myelopoiesis, Transient abnormalmyelopoiesis accompanied by hepatic fibrosis in two infantswith Down syndrome, 973
Transplantation, Detection of cytomegalovirus using PCR inserum from renal transplant recipients, 575
Transport medium, Effect of transport medium andtransportation time on culture of Helicobacter pylori from gastricbiopsy specimens: correspondence, 91
Transurethral prostatectomy, Macroscopic examination ofprostatic specimens: leader, 693
Tuberculin, Enhanced expression of type 1 procollagen andtransforming growth factor-beta in tuberculin induced delayedtype hypersensitivity, 339
Tuberculosis, Lesser known mycobacteria: leader, 701Tumour histopathology, Audit of tumour histopathology
reviewed by a regional oncology centre, 245Tumour necrosis factor, Increased gastric production of
interleukin-8 and tumour necrosis factor in patients withHelicobacter pylori infection, 133
Tumour pathology, Audit of tumour pathology reviewed by aregional oncology centre: correspondence, 690
UUlcerative colitis
Effect of proctocolectomy on serum antineutrophil cytoplasmicantibodies in patients with chronic ulcerative colitis, 645
Histological discrimination of idiopathic inflammatory boweldisease from other types of colitis, 749
Intraepithelial and lamina propria leucocyte subsets ininflammatory bowel disease: an immunohistochemical studyof colon and rectal biopsy specimens, 743
Serological markers to differentiate between ulcerative colitisand Crohn's disease, 346
Urea hydrolysis, Intragastric urea hydrolysis in children infectedwith Helicobacter pylon: correspondence, 187
Urinalysis, Routine urinalysis in renal transplant patients, 383Urinary tract infection, Evaluation of the Cult-Dip Plus dip
slide method for urinary tract infection, 710Urogenital system, Necrobiotic granulomas of the urogenital
system: correspondence, 690Urothelial cancer, The clinical value of urinary cytology: 12
years of experience with 615 patients, 314Uterine stromal sarcoma, Uterine stromal sarcoma following
tamoxifen treatment: correspondence, 596Uteroplacental ischaemia, Observer reliability in assessing
placental maturity by histology, 420Uvitex 2B, Tissue diagnosis of intestinal microsporidiosis using
a fluorescent stain with Uvitex 2B, 1009
VVagina, Brenner tumour of the vagina, 678Vancomycin, Systemic absorption of vancomycin: correspondence,689
Vancomycin resistance, Neomycin blood agar as a selectivemedium for vancomycin resistant Enterococcus faecium, 1068
Variation, Pathologist variation in reporting cervical borderlineepithelial abnormalities and cervical intraepithelial neoplasia,59
Vascular anomaly, An unusual case of colonic angiodysplasia,272
VasculitisFormalin fixation and patterns of antineutrophil cytoplasmic
antibodies, 89Isolated testicular vasculitis mimicking a testicular neoplasm:
correspondence, 496Vasodilators, Orthostatic hypotension and vasodilatory peptides
in bronchial carcinoma, 1102Vertebral artery, A necropsy and histomorphometric study of
abnormalities in the course of the vertebral artery associatedwith ossified stylohyoid ligaments, 637
Villitis of unknown aetiology, Expression of MHC class IIantigens by placental villi: no relationship with villitis ofunknown origin, 494
Villous lymphocytes, Splenic lymphoma with circulating villouslymphocytes, 584
Vimentin, Cimentin and cytokeratin expression in nodularhyperplasia and carcinoma of the prostate, 1031
Virology, Internal quality assurance in a clinical virologylaboratory. II. Internal quality control, 198
Visceral giant celi arteritis, Idiopathic granulomatous vasculitis:response to immunosuppressive therapy, 579
Volatile organic compounds, Origins of breath isoprene:correspondence, 979
Vulva, Pseudoangiosarcomatous carcinoma of the genitourinarytract, 1059
wWaldenstrom's macroglobulinaemia
Hypercalcaemia due to calcium binding IgM paraprotein inWaldenstrom's macroglobulinaemia, 961
Inaccurate haemoglobin estimation in Waldenstr6m'smacroglobulinaemia: correspondence, 787
Waldeyer's ring lymphomas, Association of Epstein-Barr viruswith sinonasal angiocentric T cell lymphoma, 946
Waterhouse-Friderichsen syndrome, Waterhouse-Friderichsen syndrome complicating primary biliary sepsis dueto Pasteurella multocida in a patient with cirrhosis, 775
Western blotting, Chromogranin positive cells in colorectalcarcinoma and transitional mucosa, 754
Wound healing, Epidermal differentiation and dermal changesin healing following treatment of surgical wounds with sheetsof cultured allogeneic keratinocytes, 1087
x, chains, Comparison of haemoglobin H inclusion bodies withembryonic globin in screening for alpha thalassaemia, 861
yYeasts, Evaluation of the AUXACOLOR system, a new method
of clinical yeast identification, 807Young adults, Free radical activity in young adult cigarette
smokers, 385
1166
The Journal of the Association of Clinical Patbologists
VOLUME 48 * 1995
Editor: David LoevvAssistant Editor: Heleni HolzelYClchalZ1 Editor: Andrea HorganEditorial Assistant: -Mavis Burrell
EDITORIAL BOARDA L AppletonC C BirdA WV BovlstonD BurnettJ Crocker
J D) DaviesF V FlvnnD J GoldieJ H E HayekF D Lee
J S LllcymanA J MalcolmJ H -McCarthyR N PeelM4 D Penney
R S PereiraGL Ridg-wavC RobertsD N SlaterR C Spencer
D Tarin1) R TurnerD A NWinfieldB WVoodcockEditor. JiA.U
PuNbishingG lJlp