opportunistic infections and aids
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Opportunistic Infections and AIDS
Andy Catanzaro, MD
Infectious Diseases
Unity Health Care, Inc
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Objectives
Recognize the relationship between CD4 and Opportunistic Infections
Recognize common Opportunistic Infections
Understand prophylaxis for Opportunistic Infections
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Clinical Case
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HIV Pathogenesis
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CD4 level and Opportunistic Infections
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Bedside methods to establish CD4 Count
Clincal Case: Thrush, wt loss
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Severe Opportunistic Infections
Most Common
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PCP pneumonia
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Candida Esophagitis
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Cryptococcal Meningitis
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Toxoplasmosis
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CMV Retinitis
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Mycobacterium avium
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Prophylaxis for Opportunistic Infections CD4 <200
PCP pneumonia prophylaxis Trimethoprim/Sulfamethoxasole
(Bactrim/Septra) Dapsone Daily dosing or three times a week
CD4 <100 Mycobacterium Prophylaxis
Zithromax (Azithromcyin) 1200 mg daily
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Clinical Case
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Conclusions
AIDS Opportunistic infections occur as CD4<200
Opportunistic infections occur commonly Prophylaxis for AIDS conditions or
CD4<200 with Bactrim/Septra daily or TIW CD4<100 with Zithromax weekly