opportunities at the alexander von humboldt foundation (avh)
TRANSCRIPT
Opportunities at the Alexander von
Humboldt Foundation (AvH)
Prof. Dr. Alessandra Sussulini
University of Campinas
Institute of Chemistry
Department of Analytical Chemistry
Campinas, September 26th 2016
CAPES-Humboldt Research Fellowship
For Brazilian Researchers: Joint fellowship program
(until 31 July 2017).
Postdoctoral Researchers: If you are at the beginning of
your academic career and completed your doctorate less
than 4 years ago. Duration: 6-24 months.
Experienced Researchers: If you are a scientist (Assistant
Professor or Junior Research Group Leader) and completed
your doctorate less than 12 years ago. Duration: 6-18
months (flexible).
Humboldt Research Fellowship for Postdoctoral Researchers
German course: up to 4 months
prior to the research fellowship
(including accompanying spouse)
My research experience in Germany:
Metallomics in the study of brain
diseases
BrainMet - Bioimaging of Metals in
Brain and Metallomics
Forschungszentrum Jülich - BrainMet
Dr. habil. J. Sabine Becker
What is Metallomics?
Genomics
Transcriptomics
Proteomics
Metabolomics
DNA
RNA
Proteins
Lipids Sugars Amino
acids
Nucleotides
Metallomics Metalloproteins Free elements
Systems biology
Degenerative disorder of the central
nervous system:
Loss of dopamine in substantia nigra
Protein accumulation (Lewy bodies)
in brain cells
Causes:
Genetic or environmental
factors
Diagnosis:
Medical history and
neurological examination
Treatment:
Only management
(levodopa)
http://nihseniorhealth.gov/parkinsonsdisease/
Parkinson’s Disease
Forschungszentrum Jülich in collaboration
with Philipps Universität Marburg
Study of mouse models of Parkinson’s disease induced by
6-hydroxydopamine (6-OHDA):
Only PD induced, n = 6
Treated with L-DOPA (L-3,4-dihydroxyphenylalanine), n = 12
6-OHDA injection
(PD)
Control
(without PD)
Parkinson’s Disease Metallomics
Parkinson’s Disease Metallomics
Animal
experiment
LA-ICP-MS
(Elemental
MS imaging)
Forschungszentrum Jülich in collaboration
with Philipps Universität Marburg
Higher concentration in animals without
L-DOPA treatment (control):
Fe in striatum
Mn in cortex and ventral forebrain nucleus
Zn in agranular insular cortex posterior (AIP)
Cu in hypothalamus and periventricular zone
Parkinson’s Disease Metallomics
Impact of the AvH fellowship in my carreer
During the fellowship period (2011-2012): 2 papers
(Metallomics and Biomedical Spectroscopy & Imaging), 5
conferences (3 in Germany, 1 in Brazil, 1 in the USA).
After the fellowship period: 3 papers: Mass Spectrometry
Reviews (2016), Talanta (2015), and Contrast Media &
Molecular Imaging (2013). Book chapter in progress:
Methods in Molecular Biology (Springer).
Impact of the AvH fellowship in my carreer
“Once a Humboldtian, always a Humboldtian”
AvH Alumni Programs:
Return fellowships (for reintegration at home country)
Book donations (donation of academic literature)
Participation in specialist conferences in Germany
Equipment subsides (purchase of scientific equipments)
And others… Please visit: www.avh.de
Special Thanks
Dr. Sabine Becker