Papilloma, floor of mouth.

Papilloma, lateral tongue.

Papilloma

Oral wart, palate.

Oral wart.

wart

Oral wart.

Oral wart. Immunohistochemical stain for common human papillomavirus in an oral wart. Positive, brown-staining nuclei

are seen in upper level keratinocytes.

Condyloma acuminatum.

Focal epithelial hyperplasia of the lip.

Focal epithelial hyperplasia of the buccal mucosa.

Biopsy specimen showing carcinoma in situ.

in situ carcinoma extending into salivary duct.

Squamous cell carcinoma. Small, crusted ulcerof the lower lip vermilion.

Squamous cell carcinoma. Ulcerated mass ofthe lower lip vermilion.

Squamous cell carcinoma of the gingiva.

Squamous cell carcinoma, floor of mouth.

Advanced squamous cell carcinoma of the posterior-lateral tongue.

Squamous cell carcinoma, gingiva.

Squamous cell carcinoma of the lip.

Exophytic squamous cell carcinoma of the lip.

Squamous cell carcinoma of the lateral tongue in a 34-year-old man.

Squamous cell carcinoma of the lateral tongue.

Squamous cell carcinoma of the ventral surface of the tongue.

Early squamous cell carcinoma of the floor of mouth.

Early squamous cell carcinoma of the floor of mouth.

Squamous cell carcinoma of the floor of mouth.

Squamous cell carcinoma of the floor of mouth.

Second primary squamous cell carcinoma of the palate in a 34-year-old man.

Metastasis of squamous cell carcinoma of the tongue to a submandibular lymph node.

Squamous ce ll carcinoma. Metastatic depositswithin cervical lymph nodes present as firm, painless enlargements

as seen in this patient with metastasis to a superior jugular nodefroma posterior lateral tongue carcinoma.

Well-differentiated squamous cell carcinoma.l ow-power photomicrograph showing islands of malignant squamous epithelium invading into the lamina properia.

Well-differentiated squamous cell carcinoma.High-power view showing dysplastic epithelial cells with keratin

pearl formation.

Moderately differentiated squamous cell carcinoma.Although no keratinization is seen in this medium-power

view, these malignant cells are still easily recognizable as being ofsquamous epithelial origin.

Poorly differentiated squamous cell carcinoma.The numerous pleomorphic cells within the lamina properia

represent anaplastic carcinoma.

Verru cous carcinoma. Extensive papillary, whitelesion of the maxillary vestibule.

Verrucous carcinoma. Large, exophytic, papillary mass of the maxillary alveolar ridge.

Verrucous carcinoma. Low-power photomicrographshowing marked epithelial hyperplasia with a rough, papillary

surface and keratin plugging.

Verrucouscarcinoma. High-power view showingbulbous rete ridges without significant dysplasia.

Erythroleukoplakia. Mixed red-an d-white lesionof the lateral borde r of the tongue. Biopsy revealed carcinoma

in situ.

l eu koplakia. Extensive ventra l and lateral tonguelesion containing multiple areas representi ng various possible

pha ses or clinical appearances

Moderate epithelial dysplasia. Dysplast icchanges extend to the midpo int of the ep ithelium and are character

ized by nuclear hyperchromatism. pleomorphism, and ce llularcrowding.

Ductal dysplasia. Salivary gland duct exhibitingsquamous metaplasia and dysplasia t hat originated from an overlying

surface epit helial dysplasia

Basal cell carcinoma.

Basal cell carcinoma. Noduloulcerat ive lesion ofthe upper lip demonstrating telangiectasia and small

ulceration.

Basal cell carcinoma.

Basal cell carcinoma. Pigmented basal cell carcinomaof the cheek.

Basal cell carcinoma.

Basal cell carcinoma. Note solid tumor (left) and nested tumor (right).

Basal cell carcinom a. low- power photomicrographshowing ulceration of the epidermal surface associated with

an invading tumor of hyperchromatic epithelial cells. Inset demonstratesislandsof basophilic epithelium with peripheral palisading.